Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Harris County, Texas, funds by Health and Human Services, Department of

Listing $371,323,322.42 in stimulus funds from Health and Human Services, Department of for Harris

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
HOUSTON-GALVESTON AREA COUNCIL, THE $32,245,456 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $214,851,599 allocation. See details
Administration for Children and Families 4/09/2009
BAYLOR COLLEGE OF MEDICINE $18,097,125 Trans-NIH Recovery Act Research Support This research proposal, entitled 'Building on GWAS for NHLBI-diseases: the U.S. CHARGE consortium', will leverage existing population, laboratory and computational resources to identify susceptibility genes underlying genome-wide significant and well-repl
This spending item is part of a $27,554,408 allocation. See details
National Institutes of Health 9/29/2009
TEXAS CHILDREN'S HOSPITAL $14,895,273 National Center for Research Resources, Recovery Act Construction Support DESCRIPTION (provided by applicant): The objective of this proposal is to build out 3 floors (total) in the Jan and Dan Duncan Neurological Research Institute (NRI) to accelerate research in understanding and treating disorders... Show more National Institutes of Health 3/25/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $12,580,753 ARRA - Strategic Health IT Advanced Research Projects (SHARP) This Strategic Health IT Advanced Research Projects (SHARP) Program seeks to support improvements in the quality, safety and efficiency of health care through advanced information technology.
This spending item is part of a $15,000,000 allocation. See details
Health and Human Services, Department of 3/19/2010
BAYLOR COLLEGE OF MEDICINE $11,958,994 The Human Genome Sequencing Center (HGSC) at Baylor College of Medicine is responding to this RFP to produce up to 31.5 terabases (Tb) of DNA sequence, comprising at least 400 and as many as 1000 cases, in 18 months. This will be followed by 3 optional on National Institutes of Health 9/24/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $11,089,034 ARRA - Head Start The Texas State Advisory Council on Early Childhood Education and Care (hereafter referred to as State Advisory Councilor Council) requested this funding to help lead the development of a parent and child focused, high quality, integrated system of early
This spending item is part of a $11,274,474 allocation. See details
Administration for Children and Families 9/14/2010
HOUSTON-GALVESTON AREA COUNCIL, THE $10,765,475 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $214,851,599 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $10,086,380 ARRA - Health Information Technology Extension Program Texas Gulf Coast HITECH Extension Center--This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance and information on best practices to support a... Show more
This spending item is part of a $13,234,318 allocation. See details
Health and Human Services, Department of 3/31/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $7,348,731 Trans-NIH Recovery Act Research Support This research proposal, entitled 'Building on GWAS for NHLBI-diseases: the U.S. CHARGE consortium', will leverage existing population, laboratory and computational resources to identify susceptibility genes underlying genome-wide significant and well-repl
This spending item is part of a $27,554,408 allocation. See details
National Institutes of Health 9/29/2009
GULF COAST COMMUNITY SERVICES ASSOCIATION $7,209,002 ARRA - Community Services Block Grant The CSBG ARRA award is Recovery Act funding for the Community Services Block Grant. The purpose of the program is to provide supplemental funds for job preservation, infrastructure investment, energy efficiency and science, assistance to the unemployed a
This spending item is part of a $48,148,071 allocation. See details
Administration for Children and Families 4/10/2009
BAYLOR COLLEGE OF MEDICINE $6,000,000 Trans-NIH Recovery Act Research Support Statement of Purpose: The Human Genome Sequencing Center (HGSC) will perform three levels of tumor/normal analysis. Abstract: This supplement will support tumor profiling at three levels: (a) Basic Cancer Profiling: to detect copy number variation, mea National Institutes of Health 9/30/2009
ADVANCE INC $5,579,595 ARRA - Early Head Start Award Description: The AVANCE-Housotn, Inc. ARRA Early Head Start Expansion provides for the funding of 208 infants and toddlers and pregnant women with a center based services program option. The Early Head Start (EHS) program is for low-income infan Administration for Children and Families 11/18/2009
BAYLOR COLLEGE OF MEDICINE $5,005,060 Therapeutically Applicable Research to Generate Effective Treatments (TARGET)- project to identify genomic targets in childhood cancers that can be used to develop more effective treatments. The goal is to catalogue somatic DNA changes that are associate
This spending item is part of a $20,000,000 allocation. See details
National Institutes of Health 9/04/2009
BAYLOR COLLEGE OF MEDICINE $5,000,000 Purpose: Translating scientific evidence into products for patients, clinicians and policymakers. Abstract: The gap between research findings and actual medical practice remains a concern for all citizens: -Patients, searching for information on safe Agency for Healthcare Research and Quality 9/24/2009
NEIGHBORHOOD CENTERS INC $3,899,502 ARRA - Early Head Start Under the American Recovery and Reinvestment Act of 2009 Early Head Start Expansion will support NCI in delivering high-quality services to an additional 140 eligible individuals and their families in a flexible array of cener-based, home-based, combinati Administration for Children and Families 11/18/2009
ADVANCE INC $3,314,950 ARRA - Head Start The ARRA Head Start Expansion provides for the funding of 200 children ages 3-4 years for the center based services program option. Head Start promotes the school readiness of low-income children by providing them with comprehensive health, developmenta Administration for Children and Families 9/18/2009
UNIVERSITY OF TEXAS M D ANDERSON $3,301,314 Trans-NIH Recovery Act Research Support HDAC CLASS IIA SPECIFIC PET RADIOTRACERS FOR PET IMAGING OF CNS National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $2,998,515 Trans-NIH Recovery Act Research Support Statement of Purpose (15 words): To identify which genes harbor individual or collections of rare DNA variants predisposing autism. Abstract: We propose a partnership between expert large-scale sequencing centers and a collaborative network of research la National Institutes of Health 9/24/2009
APOCELL, INC. $2,927,037 Phase I/II Clinical Trials and Pharmacodynamics NCIG??s Division of Cancer Treatment and Diagnosis (DCTD), under the umbrella of the American Recovery and Reinvestment Act of 2009 (ARRA), is requesting support for several new and expanded initiatives. The
This spending item is part of a $10,200,000 allocation. See details
National Institutes of Health 2/04/2010
BAYLOR COLLEGE OF MEDICINE $2,482,348 Trans-NIH Recovery Act Research Support Alterations in the epigenome have been shown to be a layer of regulation of gene expression in development and differentiation. Both chromatin modifications and DNA methylation are important in these processes. Relatively little is known about these cha National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $2,456,443 Trans-NIH Recovery Act Research Support This proposal responds to the GO Program 'ARRA Medical Sequencing Discovery Projects' to establish next-generation technologies for medical resequencing in smaller academic laboratories compared to larger facilities like the Genomic Sequencing Centers. In
This spending item is part of a $2,766,567 allocation. See details
National Institutes of Health 9/30/2009
HOUSTON-GALVESTON AREA COUNCIL, THE $2,441,039 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $214,851,599 allocation. See details
Administration for Children and Families 4/09/2009
NEIGHBORHOOD CENTERS INC $2,017,305 ARRA - Head Start The ARRA Head Start Expansion Grant serves an additional 120 preschool-age children and families, including students with disabilities, in both center-based and collaboration programs. There are 1 center based location (Hiram Clarke) and 2 collaboration l Administration for Children and Families 9/17/2009
IONWERKS, INC. $2,000,673 Trans-NIH Recovery Act Research Support Overall Goal:-Obtain maximum molecular information by Mass Spectrometry from a single 10 micron diameter cell. Ionwerks has created new classes of nanoparticulate (NP) matrices which can be localized in submonolayer amounts on or within the first several
This spending item is part of a $2,996,567 allocation. See details
National Institutes of Health 8/23/2010
GREATER HOUSTON HEALTH INFORMATION EXCHANGE $1,975,452 ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health ... Show more
This spending item is part of a $28,810,208 allocation. See details
Health and Human Services, Department of 3/15/2010
BAYLOR COLLEGE OF MEDICINE $1,956,173 Trans-NIH Recovery Act Research Support The comparative effectiveness (CE) of screening endoscopy in patients with GERD symptoms (vs. no screening) or among different surveillance strategies (frequency, intensity) is unclear due to lack of strong evidence-based findings for GERD or Barrett's es National Institutes of Health 9/30/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $1,844,556 Trans-NIH Recovery Act Research Support Preeclampsia (PE) is a dangerous complication of pregnancy characterized by sudden onset hypertension, proteinuria, inflammation, and coagulopathy. The condition affects approximately 7% of first pregnancies and accounts for over 80,000 premature births e National Institutes of Health 9/24/2010
UNIVERSITY OF TEXAS M D ANDERSON $1,738,058 Trans-NIH Recovery Act Research Support TRANSCRIPTOME AND EPIGENOME ANALYSIS OF HELPER T CELL SPECIFICATION AND PLASTICIT
This spending item is part of a $2,759,411 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,735,224 Trans-NIH Recovery Act Research Support Bioethics Initiative For Equity In Health Care And Research At The University Of Texas M. D. Anderson Cancer The overarching goal of the proposed Bioethics Initiative for Equity in Health Care and Research will be to develop a diverse, multidisciplinary, National Institutes of Health 9/27/2009
WILLIAM MARSH RICE UNIVERSITY $1,630,720 Trans-NIH Recovery Act Research Support Rice University is proposing the acquisition of a 24 TeraFLOP Computational Biology Cluster, based on the new Intel Nehalem technology, and equipped with hybrid InfiniBand/GigE interconnect to support both tightly coupled MPI and loosely coupled high-thro National Institutes of Health 8/12/2010
HARRIS COUNTY DEPARTMENT OF EDUCATION $1,624,582 ARRA - Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. HCDE Head Start received Expansion(ARRA) Year 1-2 to provide full day Head Start services to 80 children a Administration for Children and Families 9/18/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $1,514,173 Trans-NIH Recovery Act Research Support The combined threat of cardiovascular disease (CVD) and obesity is arguably the worst major health problem affecting the western world. While there has been progress in reducing CVD mortality, death rates remain unacceptably high. Current approaches to tr
This spending item is part of a $2,921,456 allocation. See details
National Institutes of Health 9/30/2010
BAYLOR COLLEGE OF MEDICINE $1,454,750 Trans-NIH Recovery Act Research Support Newly Independent Faculty Physician Recruit Supplement to study the Epigenetic Changes in Malignancy: Therapeutic Targeting of Aberrant DNA Methylation. The proposed newly independent faculty recruit will perform laboratory research to more fully chara National Institutes of Health 9/23/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,432,787 Recovery Act Comparative Effectiveness Research - AHRQ The Agency for Health Care Research and Quality (AHRQ), through its Effective Health Care Program (http://effectivehealthcare.ahrq. gov), supports the development of comparative effectiveness reviews (CERs), many of which have associated products... Show more
This spending item is part of a $1,497,995 allocation. See details
Agency for Healthcare Research and Quality 9/01/2010
BAYLOR COLLEGE OF MEDICINE $1,386,953 Trans-NIH Recovery Act Research Support 'Preclinical development of a therapeutic methamphetamine conjugate vaccine for substance abuse. ABSTRACT: Immunization against methamphetamine (MA) is potentially valuable in assisting patients in stopping their abuse. Vaccines against both nicotine and National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $1,385,719 Trans-NIH Recovery Act Research Support Very little is known about the genetic alterations contributing o the development and progression of oral cancer. Currently, there are no large scale genomic studies addressing these issues, presumably owing to the cost and difficulties associated with su
This spending item is part of a $2,398,656 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,372,495 Trans-NIH Recovery Act Research Support CYCORE: CYBERINFRASTRUCTURE FOR COMPARATIVE EFFECTIVENESS RESEARCH
This spending item is part of a $3,866,878 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $1,337,736 Trans-NIH Recovery Act Research Support This project addresses the G?Applying Genomics and Other High Throughput TechnologiesG? thematic area. HIV-associated nephropathy (HIVAN) is a unique disease that results from the interplay of environmental factors (HIV), host responses to the virus, and
This spending item is part of a $1,950,000 allocation. See details
National Institutes of Health 9/29/2010
HOUSTON AREA COMMUNITY SERVICES, INC $1,300,000 ARRA Health Center Integrated Services Development Initiative[g1] Houston Area Community Services, Inc. (HACS) is a non-profit, community-based enterprise founded in 1997 that specializes in identifying emerging health and human services needs, and addressing disparities among underserved communities... Show more Health Resources and Services Administration 2/26/2009
MOTHERLAND INC $1,300,000 ARRA Health Center Integrated Services Development Initiative[g1] ARRA-RECOVERY ACT HEALTH CENTER CLUSTER PROGRAM Health Resources and Services Administration 2/26/2009
HOUSTON COMMUNITY COLLEGE, INC. $1,287,568 ARRA - Health Information Technology Professionals in Health Care Pitt Community College Region D Consortium - will seek to rapidly create HIT academic programs at Community Colleges or expand existing ones. Community Colleges are G?institutions of higher educationG? as defined by section 101 of the ... Show more
This spending item is part of a $20,817,547 allocation. See details
Health and Human Services, Department of 4/02/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $1,265,463 ARRA Grants for Training in Primary Care Medicine and Dentistry Training and Enhancement Title: ARRA Postdoctoral Training in General, Pediatric and Public Health Dentistry and Dental Hygiene. The purpose of this grant is to develop and expand a community-linkage general dentistry (AEGD) program in... Show more Health Resources and Services Administration 8/23/2010
BAYLOR COLLEGE OF MEDICINE $1,191,935 Trans-NIH Recovery Act Research Support The major goals of this project are to establish a method for optical analysis of neural circuits. Neuroplasticity is central to fundamental processes in the brain, including learning, recovery after brain injury, and neural circuit changes resulting from
This spending item is part of a $1,220,072 allocation. See details
National Institutes of Health 8/14/2009
BAYLOR COLLEGE OF MEDICINE $1,184,308 Recovery Act Comparative Effectiveness Research - AHRQ SUMMARY PURPOSE: Adapt already-translated products and information from CER reviews for use in schools. ABSTRACT: The Center for Educational Outreach at Baylor College of Medicine (BCM) proposes an innovative, school-based approach to adapting... Show more Agency for Healthcare Research and Quality 8/12/2010
BAYLOR COLLEGE OF MEDICINE $1,156,554 Trans-NIH Recovery Act Research Support PURPOSE: The goal of this project is to determine the developmental fate and gene expression of the head surface ectoderm in the absence of the retina. Identification of these genes and developmental processes will lead to the better understanding of eye National Institutes of Health 9/01/2009
BAYLOR COLLEGE OF MEDICINE $1,149,025 Trans-NIH Recovery Act Research Support We propose to map and deposit a collection of well defined chemically induced mutations in essential genes on the Drosophila melanogaster X chromosome for distribution by the Bloomington Drosophila Stock Center (BDSC) to the fly community. This resource w
This spending item is part of a $1,657,258 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF TEXAS M D ANDERSON $1,127,915 Trans-NIH Recovery Act Research Support The proposed study continues a previously NCI-funded smoking cessation project that used motivational interviewing technique and health-status feedback (respiratory symptoms, lung function, and carbon monoxide in expired air) to induce and accelerate juni
This spending item is part of a $1,331,493 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF HOUSTON SYSTEM $1,125,000 Trans-NIH Recovery Act Research Support Global multiple sequence alignment is the most basic step in the comparative study of molecular sequences. It is also the foundation of numerous subsequent biological analyses, such as phylogenetic reconstruction, gene annotation, and three-dimensional st National Institutes of Health 5/07/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,122,429 Trans-NIH Recovery Act Research Support In this proposal, we build upon an epidemiologic risk model for lung cancer that we recently developed from a lung cancer case-control study of 1851 Caucasian lung cancer patients and 2001 controls, matched to the cases on sex, age (15 years), smoking sta
This spending item is part of a $1,362,331 allocation. See details
National Institutes of Health 8/12/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $1,120,209 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
BAYLOR COLLEGE OF MEDICINE $1,113,035 Trans-NIH Recovery Act Research Support Our plan is to develop a new therapy for heart disease. Abstract: Cardiovascular disease is a major cause of mortality and morbidity and development of therapies that address its underlying causes is an important public health priority. With better ma
This spending item is part of a $1,176,035 allocation. See details
National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $1,084,524 Trans-NIH Recovery Act Research Support The relevance to public health is that the project will enhance our understanding and provide new insights into mechanisms for chromosomal abnormalities that result from nonrecurrent rearrangements. Such genome rearrangements cause gene copy number change National Institutes of Health 7/17/2009
TEXAS HEART INSTITUTE $1,073,030 Trans-NIH Recovery Act Research Support This grant supports a new independent investigator in molecular cardiology research. The new investigator will study genetic and molecular aspects of congenital heart defects (CHDs) with the goal of providing new insights into the mechanisms underlying d National Institutes of Health 9/30/2009
WILLIAM MARSH RICE UNIVERSITY $1,053,241 Trans-NIH Recovery Act Research Support Oral cancer, largely oral squamous cell carcinoma (OSCC), is a global health problem afflicting close to 300,000 people each year. Despite significant advances in surgical procedures and treatment, the long-term prognosis for patients with OSCC remains po
This spending item is part of a $1,955,950 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,051,688 UT-MD Anderson Cancer Center has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of clear cell renal cancer specimens (300 cases). These cases are all National Institutes of Health 4/28/2010
NEIGHBORHOOD CENTERS INC $1,048,411 ARRA - Head Start This award provides for ARRA cost of living adjustment (cola), and Quality Improvement Funding for Head Start and Early Head Start program. The proposed spending in this area is necessary in order to provide our students with facilities that are secure an Administration for Children and Families 6/29/2009
GULF COAST COMMUNITY SERVICES ASSOCIATION $1,039,580 ARRA - Head Start Gulf Coast Community Services Association (GCCSA) is funded to serve 1864 Head Start Children and 84 Early Head Start Children age infant to 5 years and pregnant women in Harris County and in the Fifth Ward area of Houston. The American Recovery and Inve Administration for Children and Families 7/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,030,000 Trans-NIH Recovery Act Research Support The University of Texas M. D. Anderson Cancer Center (MDACC) is a free-standing comprehensive cancer center within the University of Texas system. The mission of the MDACC is to eliminate cancer in Texas, the nation and the world through outstanding integ National Institutes of Health 9/17/2010
UNIVERSITY OF TEXAS M D ANDERSON $1,013,000 Trans-NIH Recovery Act Research Support The Radiation Therapy Oncology Group (RTOG), which is one of the largest and most established cooperative groups in oncology, has developed a recursive partitioning analysis (RPA) model for malignant glioma patients, using primarily clinical and demograph
This spending item is part of a $2,056,531 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,012,937 Trans-NIH Recovery Act Research Support Very little is known about the genetic alterations contributing o the development and progression of oral cancer. Currently, there are no large scale genomic studies addressing these issues, presumably owing to the cost and difficulties associated with su
This spending item is part of a $2,398,656 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $1,000,000 Trans-NIH Recovery Act Research Support In response to: 14-CA-102 Understanding the Heterogeneity of Cancer and its Environment. Assembly and disassembly of stromal architecture in the tumor microenvironment. Frank Marini- UTM.D. Anderson Cancer Center To meet the requirements for rapid tumor g National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $999,983 Trans-NIH Recovery Act Research Support Transplantation of hematopoietic stem cells (HSCs) derived from high-quality sources of tissue-matched bone marrow, mobilized peripheral blood or umbilical cord blood represents the therapeutic option of choice for the treatment of hematological malignanc National Institutes of Health 4/08/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $994,635 Trans-NIH Recovery Act Research Support Cellular transplantation of lung stem/progenitor cells represents a potential therapeutic approach for a variety of inherited lung diseases. Crucial to the success of such a therapeutic strategy is that the transplanted cells and their progeny are correct National Institutes of Health 4/08/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $992,972 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-DK-103: 'Translate discovery of new molecules/pathways in pathogenesis of NIDDK diseases in potential therapies.' We have assembled a team of exper National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $984,128 Trans-NIH Recovery Act Research Support According to the World Health Organization, 15 million people worldwide suffer a stroke every year. Of these, 5 million die and another 5 million are left permanently disabled, placing a heavy burden on families, communities, and governments. While patien
This spending item is part of a $1,550,402 allocation. See details
National Institutes of Health 6/01/2009
ADVANCE INC $970,157 ARRA - Head Start The ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding award is aligned with the requirements of Section 640 (a) (5) of the Head Start Act for the Head Start and Early Head Start programs. The Early Head Start (EHS) program is for lo Administration for Children and Families 7/01/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $962,400 Trans-NIH Recovery Act Research Support People expect their primary care physician to be their point of access to healthcare and to assure that the care they receive within the system is evidence-based, cost-effective, coordinated, and safe. Unfortunately, primary care providers do not have the National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $962,322 Trans-NIH Recovery Act Research Support Applying Genomics and Other High Throughput Technologies is the thematic area that this application addresses. Ovarian cancer is the most lethal gynecologic malignancy. It has a high response rate to initial combined platinum taxane chemotherapy following
This spending item is part of a $3,723,748 allocation. See details
National Institutes of Health 9/27/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $929,537 Trans-NIH Recovery Act Research Support Purpose of Supplement. This administrative supplement complements the goals of the parent PAGE project. It provides funds to genotype additional susceptibility variants in approximately 2,500 African American study participants in CALiCo G?? PAGE. If the
This spending item is part of a $980,581 allocation. See details
National Institutes of Health 9/04/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $925,209 Trans-NIH Recovery Act Research Support Challenge Area and Specific Challenge Topic: This application addresses broad Challenge Area (10) Information Technology for Processing Health Care Data and specific Challenge Topic, 10-RR-101*: Information Technology Demonstration Projects Facilitating S
This spending item is part of a $951,766 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $900,354 Trans-NIH Recovery Act Research Support Very recently channelrhodopsins, light-gated ion channels we found in 2002 to be phototaxis receptors that mediate light-induced membrane depolarization in Chlamydomonas algae, have been intensively used for non-invasive, highly temporally and spatially r National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $900,000 Trans-NIH Recovery Act Research Support The proposed Genome Data Analysis Center B (GDAC B) will work cooperatively with other GDACs funded by The Cancer Genome Atlas (TCGA) project to (i) develop an innovative, integrative pipeline for systems- level analysis of TCGA's molecular profiling data National Institutes of Health 9/23/2010
UNIVERSITY OF TEXAS M D ANDERSON $892,724 Trans-NIH Recovery Act Research Support The MENTORS project will make a crucial contribution to biomedical research and public health by enhancing recruitment of minority and underserved students into scientific and clinical careers. Furthermore, many rural areas in Texas are medically underser National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $879,122 MD Anderson Cancer Center has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of head and neck (300 cases) under delivery order HHSN26100001. These ca National Institutes of Health 6/15/2010
BAYLOR COLLEGE OF MEDICINE $875,882 Trans-NIH Recovery Act Research Support 'The purpose of this grant is to improve the prevention of cardiovascular disease by using recent genetic discoveries to identify who is at risk of developing a heart attack and by improved understanding of the genes that control the levels of fats (trigl
This spending item is part of a $996,476 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $867,523 Trans-NIH Recovery Act Research Support This program is comprised of four highly interactive projects from Baylor College of Medicine (BCM) and M.D. Anderson Cancer Center (MDACC) in the Texas Medical Center (TMC) in Houston that focus on different aspects of the regulation of self-renewal and
This spending item is part of a $1,261,211 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $846,385 Trans-NIH Recovery Act Research Support Tobacco related lung diseases, including chronic obstructive pulmonary disease (COPD) with and without emphysema, are among the major causes of lung-related disability and death worldwide. The immediate cause of emphysema is destruction of lung matrix, es National Institutes of Health 5/30/2009
BAYLOR COLLEGE OF MEDICINE $840,933 Trans-NIH Recovery Act Research Support Statement of Purpose: Identifying novel mechanisms of cell death regulation for stroke, heart disease and cancer National Institutes of Health 8/04/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $828,681 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $2,008,515 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $825,281 Trans-NIH Recovery Act Research Support 'This project is aimed at developing rational strategies for the prevention and treatment of lung diseases such as BPD and ARDS in humans.. Hyperoxia is frequently used in the treatment of pulmonary insufficiency in premature infants. However, hyperox
This spending item is part of a $855,818 allocation. See details
National Institutes of Health 5/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $822,583 Trans-NIH Recovery Act Research Support The Specific Aims of the proposal is modified to reflect a change in scope, according to recommendations from the review panel. The aims of this Phase II continuation proposal are to utilize fully humanized recombinant lactoferrin (rhLF) as an adjuvant
This spending item is part of a $2,977,916 allocation. See details
National Institutes of Health 9/07/2009
UNIVERSITY OF HOUSTON SYSTEM $812,160 Trans-NIH Recovery Act Research Support Dramatic advancements in nanomagnetic sensor technology, driven by the needs of magnetic data storage industry, have now brought us disk drives with magnetic read heads addressing features of less than 80nm across, at a wholesale cost of about
This spending item is part of a $961,864 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $810,394 Trans-NIH Recovery Act Research Support The long-term objective of this Program Project is to perform a systematic analysis of the cellular and molecular mechanisms regulating thymic epithelial cell (TEC) homeostasis and the role of TECs in the involution of the adult thymus. The thymus is the
This spending item is part of a $1,995,177 allocation. See details
National Institutes of Health 8/13/2009
UNIVERSITY OF TEXAS M D ANDERSON $809,702 Trans-NIH Recovery Act Research Support The sympathetic drive emanating from the brain is increased in animal models of hypertension and in patients with hypertension. The paraventricular nucleus (PVN) of the hypothalamus is an important site for the control of sympathetic outflow through its p National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $800,001 Trans-NIH Recovery Act Research Support Generate Shank3 conditional knock-out mice line. This proposal is responsive to RFA-MH-09-170, the Recovery Act Limited Competition: Research to Address the Heterogeneity in Autism Spectrum Disorders (R01). As noted in the RFA, Autism spectrum disorders ( National Institutes of Health 9/25/2009
BAYLOR COLLEGE OF MEDICINE $799,122 Trans-NIH Recovery Act Research Support 'The roles of the V-ATPase at the molecular and physiological level will be investigated. The V0 sector subunit G?aG? has been shown to play important roles in diverse membrane fusion or secretion functions independent of the V-ATPase proton-pumping activ
This spending item is part of a $970,890 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $796,746 Trans-NIH Recovery Act Research Support Diabetic neuropathy is one of the most important complications that afflict people with diabetes. Because chronic pain caused by diabetic neuropathy is not adequately relieved by existing analgesics, it represents an important unmet clinical need. The cho National Institutes of Health 7/17/2009
PHARMAREVIEW CORPORATION $778,908 Trans-NIH Recovery Act Research Support The Specific Aims of the proposal is modified to reflect a change in scope, according to recommendations from the review panel. The aims of this Phase II continuation proposal are to utilize fully humanized recombinant lactoferrin (rhLF) as an adjuvant
This spending item is part of a $2,977,916 allocation. See details
National Institutes of Health 9/07/2009
UNIVERSITY OF TEXAS M D ANDERSON $770,000 Trans-NIH Recovery Act Research Support Aspergillus fumigatus and other species are increasingly the cause of morbidity and mortality among immunocompromised patients. Infections caused by these fungi are most prevalent in neutropenic patients with hematological malignancies. In the past few ye National Institutes of Health 5/06/2009
UNIVERSITY OF TEXAS M D ANDERSON $770,000 Trans-NIH Recovery Act Research Support T cell activation and tolerance are tightly regulated to assure effective elimination of infectious pathogens while maintaining tolerance to self-tissues. T cell immunity vs tolerance decision is, on one hand, determined by the extracellular signals deliv National Institutes of Health 5/15/2009
UNIVERSITY OF TEXAS M D ANDERSON $769,945 Trans-NIH Recovery Act Research Support Mastery of written and oral communication skills is essential for the survival of faculty everywhere. It can be a challenge for scientists from any background, but may be especially difficult for those who are educationally under-prepared or who have had National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $767,500 Trans-NIH Recovery Act Research Support To study the function of the nuclear receptor LRH-1. The orphan receptor LRH-1/NR5A2 is thought to be a key regulator of the complex process of bile acid biosynthesis and potentially other important metabolic pathways in the liver, but there is very littl National Institutes of Health 7/17/2009
BAYLOR COLLEGE OF MEDICINE $767,500 Trans-NIH Recovery Act Research Support The purpose of this grant is to understand how Notch signaling suppresses the differentiaiton of lens fiber cells. Our recent studies indicate that the Notch signaling pathway inhibits lens fiber cell differentiation. We found that Herp2, a transcripti National Institutes of Health 5/21/2009
BAYLOR COLLEGE OF MEDICINE $767,500 Trans-NIH Recovery Act Research Support The goal of this supplement will be to support our studies on the intercellular bridge. Intercellular communication is essential for all multicellular organisms. A unique form of intercellular communication occurs between germ cells; 0.5-3 mm G?channelsG? National Institutes of Health 7/29/2009
BAYLOR COLLEGE OF MEDICINE $767,500 Trans-NIH Recovery Act Research Support Fight quinolone-resistant and multidrug-resistant bacterial infections. Fluoroquinolones are the most frequently prescribed antimicrobial agents in the United States. Fluoroquinolone- and multidrug-resistant bacteria are emerging infectious disease agent National Institutes of Health 7/17/2009
UNIVERSITY OF TEXAS M D ANDERSON $762,867 Trans-NIH Recovery Act Research Support How animals regulate organ size is unknown. Recent studies in Drosophila point towards a novel signaling pathway called hippo as an important regulator of organ growth. Cells that are mutant for components of the hippo signaling pathway exhibit features o National Institutes of Health 7/13/2009
LEGACY COMMUNITY HEALTH SERVICES, INC. $757,745 ARRA Health Center Integrated Services Development Initiative[g1] Grant Name:ARRA - Capital Improvement Program Purpose: Provide funds for information technology so the health center can implement an electronic health records system. Goals: Acquire the information technology equipment needed to sup... Show more Health Resources and Services Administration 6/25/2009
BAYLOR COLLEGE OF MEDICINE $748,233 Trans-NIH Recovery Act Research Support This supplemental award provides support to Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Supplements including: 1) High Risk Acute Lymphoblastic Leukemia (HR-ALL) - Our results establish that we can use comprehensive genom
This spending item is part of a $4,023,579 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $744,411 Trans-NIH Recovery Act Research Support The long term objective of this proposal is to gain insights into the neuron generation potential of the mammalian retinal-ciliary margin as well as the molecular and cellular properties of cells within. This has important implications for the regeneratio National Institutes of Health 7/20/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $741,432 Trans-NIH Recovery Act Research Support Argatroban, a thrombin inhibitor, has been studied in the setting of both coronary perfusion as well as acute ischemic stroke. Since the majority of ischemic stroke patients may not benefit from rt-PA alone, the combination of thrombolytics with anticoagu
This spending item is part of a $1,096,944 allocation. See details
National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $732,684 Trans-NIH Recovery Act Research Support Medication development for substance dependence. abstract:This application addresses broad NIH Challenge Area 04: Clinical Research and specific Challenge Topic 04-DA-101: Evaluation of novel, rationalized poly-pharmacotherapeutic treatment strategies for National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $729,951 Trans-NIH Recovery Act Research Support Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estrogen recept
This spending item is part of a $1,906,255 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $722,753 Trans-NIH Recovery Act Research Support Patient navigation (PN) is a community-centered approach that can potentially reduce health disparities by enhancing access to care at an earlier stage of the disease continuum for underserved populations, such as racial/ethnic minorities or individuals w National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $716,480 Trans-NIH Recovery Act Research Support The overall goal of the program is to identify genes that predispose to childhood cancer, the molecular pathways to tumor development, and the clinical implications. We have focused on two model familial syndromes of childhood and adolescent cancers, sarc National Institutes of Health 9/14/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $715,981 Trans-NIH Recovery Act Research Support Area V4 is a key component of primate visual cortex that is involved in many aspects of 'intermediate' processing including higher-order shape processing, color constancy, and attention. V4 performs more complex computations than lower areas V1 or V2, but National Institutes of Health 6/19/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $699,950 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Over 400,000 Americans have end-stage renal disease (ESRD) requiring dialysis or kidney transplant for survival. ESRD in the US population doubled in the last decade and this increase is driven by diabetes and hyperten National Institutes of Health 9/23/2009
UNIVERSITY OF TEXAS M D ANDERSON $699,669 Trans-NIH Recovery Act Research Support Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estrogen recept
This spending item is part of a $1,906,255 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF HOUSTON SYSTEM $695,388 Trans-NIH Recovery Act Research Support Asthma is characterized by airway obstruction, airway hyperresponsiveness (AHR) and airway inflammation. The medications used for control and acute relief of asthma may vary in effectiveness and produce serious side effects. Also, ~30% of asthma patient
This spending item is part of a $1,036,014 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $693,000 Trans-NIH Recovery Act Research Support Innate immunity plays a crucial role in initiating the immune responses and pathogen clearance upon microbial infection. Using pattern recognition receptors including cell surface receptor such as Toll-like receptors (TLRs) or intracellular receptors such National Institutes of Health 6/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $693,000 Trans-NIH Recovery Act Research Support This application is in response to NOT-OD-09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Different individuals exposed to the same environmental agent often respond differently due to additional factors National Institutes of Health 9/17/2009
BAYLOR COLLEGE OF MEDICINE $692,986 Trans-NIH Recovery Act Research Support 'We propose to enrich the technology infrastructure of our Cryo-EM P41 CenterWe propose to enrich the technology infrastructure of our Cryo-EM P41 Center by 1) automating the cryospecimen preparation with microfluidity and robotics engineering technologie
This spending item is part of a $892,860 allocation. See details
National Institutes of Health 8/13/2009
BAYLOR COLLEGE OF MEDICINE $690,750 Trans-NIH Recovery Act Research Support 'Main goal: Understand the molecular mechanisms that govern the nicotine withdrawal syndrome. Abstract. Nicotine addiction is a major worldwide medical and social problem that continues to escalate. Affective and somatic symptoms associated with nicotine National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $688,775 Trans-NIH Recovery Act Research Support The purpose of this grant is to study the regulation of the ocular surface immune response to desiccating stress.Sj+?grenG??s syndrome causes profound dysfunction of the lacrimal functional unit (LFU) that results in decreased secretion of tear fluid and
This spending item is part of a $782,975 allocation. See details
National Institutes of Health 7/20/2009
BAYLOR COLLEGE OF MEDICINE $676,735 Trans-NIH Recovery Act Research Support The long-term objective of this application is to elucidate the molecular mechanisms underlying TGF+? regulation and functions, and understand the molecular basis of how alterations in TGF+? responses lead to deregulation of growth control in human cancer National Institutes of Health 6/01/2009
UNIVERSITY OF HOUSTON SYSTEM $675,000 Trans-NIH Recovery Act Research Support A specialized population of cells known as podocytes plays a crucial and dynamic role in establishing and maintaining the glomerular filtration barrier. Indeed, mutations in three podocyte proteins that will be studied in this research G?? TRPC6, nephrin National Institutes of Health 9/17/2009
TEXAS HEART INSTITUTE $671,933 Trans-NIH Recovery Act Research Support Adult stem cell based therapies (using a patient's own cells, not embryonic cells) have emerged as a promising approach in regenerative medicine. The ability to track transplanted stem cells after they are injected into the body is a crucial tool because
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $664,402 Trans-NIH Recovery Act Research Support Hypertension affects nearly one-third of adults over age 20 in the United States. While hypertension is found in <10% in adults 20 - 34 years of age, it develops over a period of years, and blood pressure levels in children and adolescents are correlated
This spending item is part of a $860,260 allocation. See details
National Institutes of Health 9/14/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $662,590 Trans-NIH Recovery Act Research Support Hispanic farmworkers and their families suffer a disproportionate number of injuries and illnesses associated with their work and limited personal resources. Over the next two years, we intend to establish a sustainable national farmworker research networ
This spending item is part of a $999,999 allocation. See details
National Institutes of Health 7/07/2010
UNIVERSITY OF TEXAS M D ANDERSON $659,136 Trans-NIH Recovery Act Research Support The Gulf Coast Transdisciplinary Research Recovery Center for Community Health brings together outstanding academic and public health institutions and centers as a Consortium. The Consortium will coordinate new research studies and projects with existing
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $655,500 Trans-NIH Recovery Act Research Support 'The overall goal of the DERC is to promote diabetes research in clinical metabolism and nutrition. Scope of the Overall Project: This Diabetes Endocrinology Research Center (DERC) application was submitted under a P30 grant mechanism in response to a RF
This spending item is part of a $675,500 allocation. See details
National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $646,697 Trans-NIH Recovery Act Research Support This proposal will address core items in Challenge Area 08 (Genomics), specifically targeting Challenge Topic 08-DK-107, Nuclear receptor mediated assembly of functional transcription units. In relation to this application, this Challenge Topic states: -? National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $639,104 Trans-NIH Recovery Act Research Support Multiple myeloma (MM) is still incurable B-cell malignancy affecting more than 14,000 Americans annually. Myeloma tumor cells can survive even the most aggressive treatment available today, leading to disease relapses. The long-term goal of this project i National Institutes of Health 5/15/2009
UNIVERSITY OF TEXAS M D ANDERSON $639,100 Trans-NIH Recovery Act Research Support The long-term goal of this research is to help develop improved chemopreventive interventions for colorectal cancer based on molecular targeting of crucial events in colorectal tumorigenesis. Inflammation contributes to colon carcinogenesis. Prostaglandin National Institutes of Health 6/04/2009
UNIVERSITY OF TEXAS M D ANDERSON $639,100 Trans-NIH Recovery Act Research Support The lack of efficient gene delivery systems is the most important barrier to the use of gene therapy for cancer. There is an urgent need to develop vectors that are capable of selective, efficient, and safe delivery of genes to tumors. Until this need is National Institutes of Health 7/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $639,100 Trans-NIH Recovery Act Research Support Persistence of dormant cancer cells that have resisted chemotherapy is a major barrier to curing ovarian cancer. Our group has developed the first inducible model for tumor dormancy in ovarian cancer using human ovarian cancer xenografts and has discovere National Institutes of Health 7/17/2009
BAYLOR COLLEGE OF MEDICINE $637,028 Trans-NIH Recovery Act Research Support Purpose: Identify virus and host factors important in polyomavirus SV40 infections and cancer development. Abstract: Human cancer viruses establish persistent infections in their hosts. We hypothesize that the risk of viral induced cancer is dependent o National Institutes of Health 5/07/2009
HARRIS COUNTY DEPARTMENT OF EDUCATION $632,544 ARRA - Head Start Head Start ARRA COLA and Quality Improvement Funds The action awards a cost-of-living increase of 1.84% for Head Start staff and approval of funds for minor renovations for two facilities , Sheffield and LaPorte. Administration for Children and Families 7/01/2009
BAYLOR COLLEGE OF MEDICINE $620,694 Trans-NIH Recovery Act Research Support Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant progressive myopathy affecting approximately 25,000 individuals in the United States. It is the third most common muscular dystrophy by incidence with a prevalence near or surpassin
This spending item is part of a $1,933,050 allocation. See details
National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $619,900 Trans-NIH Recovery Act Research Support Herpesviruses are major pathogens in human populations, causing disease in normal and immuno-compromised individuals. Double-stranded DNA (dsDNA) tailed bacterial viruses and herpesviruses share surprising similarities in capsid assembly and organization.
This spending item is part of a $1,011,610 allocation. See details
National Institutes of Health 5/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $616,000 Trans-NIH Recovery Act Research Support This application is submitted in response to the Notice Number (NOT-OD-09-058): NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The overall objective of this Competitive Revision (CR) application is to examine t National Institutes of Health 9/25/2009
BAYLOR COLLEGE OF MEDICINE $614,000 Trans-NIH Recovery Act Research Support Congenital Myotonic Dystrophy 1 (DM1) causes a delay of development in newborn children. There is no cure for this devastating multisystemic, neuro-muscular disease. This project will address the molecular mechanisms delaying development of muscle in pati National Institutes of Health 9/09/2009
BAYLOR COLLEGE OF MEDICINE $614,000 Trans-NIH Recovery Act Research Support Many organelles exist in an equilibrium of fragmentation into smaller units (e.g. during mitosis) and fusion into larger structures. How are size, copy number and shape of an organelle determined and how are the elementary processes of membrane fission an National Institutes of Health 8/14/2009
BAYLOR COLLEGE OF MEDICINE $613,439 Trans-NIH Recovery Act Research Support Purpose: To focus on the molecular mechanisms underlying the termination of TGF-? signaling. Abstract: The TGF-? signaling pathway represents a major growth inhibitory pathway in normal epithelial cells, and paradoxically, it promotes proli National Institutes of Health 7/16/2009
HARRIS COUNTY HOSPITAL DISTRICT $602,625 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Program Performance Narrative As of September 30 2011, the HCHP CIP has spent $569,638.00. In the last quarter, the HCHD IT department created new reports to provide operational oversight although the original repor... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $599,398 Trans-NIH Recovery Act Research Support Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the United States and Europe. Recent progress in our understanding of CLL biology and the development of new therapy such as fludarabine-based regimens has led to improvements of the National Institutes of Health 6/05/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $595,608 Trans-NIH Recovery Act Research Support Our long term objectives are to understand the biochemical mechanisms that cause the feedback inhibition of hormonal or drug stimulation of the 22-adrenergic receptor (22AR) that mediates several important components of the 'fight-or-flight' response thro
This spending item is part of a $835,037 allocation. See details
National Institutes of Health 9/22/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $589,791 Trans-NIH Recovery Act Research Support This is a revised, competitive renewal application for the Genetics of Microangiopathic Brain Injury (GMBI) study, initially funded in 2001 as an ancillary study to the Genetic Epidemiology Network of Arteriopathy (GENOA) and Family Blood Pressure Program
This spending item is part of a $1,666,669 allocation. See details
National Institutes of Health 8/04/2009
UNIVERSITY OF TEXAS M D ANDERSON $582,227 Trans-NIH Recovery Act Research Support For three decades, alterations of protein-coding oncogenes and tumor suppressors genes have been considered as the causes of tumorigenesis. Recent advances proved without doubts that cancer is a complex genetic disease involving structural and expression
This spending item is part of a $650,865 allocation. See details
National Institutes of Health 7/17/2009
UNIVERSITY OF TEXAS M D ANDERSON $581,511 Trans-NIH Recovery Act Research Support Critical issues for improving the treatment of alcoholism are what neurobiological changes are responsible for the transition from non-dependent alcohol use to alcoholism, and what persistent changes mediate relapse. The goals of the present proposal are National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $569,059 Trans-NIH Recovery Act Research Support The proposed Genome Data Analysis Center B (GDAC B) will work cooperatively with other GDACs funded by The Cancer Genome Atlas (TCGA) project to (i) develop an innovative, integrative pipeline for systems- level analysis of TCGA's molecular profiling data
This spending item is part of a $841,344 allocation. See details
National Institutes of Health 9/22/2010
UNIVERSITY OF TEXAS M D ANDERSON $568,179 Trans-NIH Recovery Act Research Support The studies address the problem of relapse of B-lineage acute lymphoblastic leukemia (B-ALL) after umbilical cord blood transplant (UCBT). We hypothesize that the incidence of relapse following allogeneic UCBT can be reduced by targeting post-transplant m National Institutes of Health 9/04/2009
CITY OF HOUSTON $564,210 Aging Congregate Nutrition Services for States ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith-based settings.
This spending item is part of a $4,012,217 allocation. See details
Administration on Aging 3/18/2009
BAYLOR COLLEGE OF MEDICINE $555,980 Trans-NIH Recovery Act Research Support The Gulf Coast Transdisciplinary Research Recovery Center for Community Health brings together outstanding academic and public health institutions and centers as a Consortium. The Consortium will coordinate new research studies and projects with existing
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/30/2009
CITY OF HOUSTON $555,156 ARRA ?Health Information Technology and Public Health The ARRA IT ELC grant is awarded to assist public health agencies in improving surveillance for and response to infectious diseases. The public health system is a key component of our nation?s healthcare system and without such a link to the clini... Show more Centers for Disease Control and Prevention 8/02/2010
TEXAS HEART INSTITUTE $550,000 Trans-NIH Recovery Act Research Support Title: Prostacyclin-secreting Cells as Therapy for Pulmonary Artery Hypertension Description: Pulmonary arterial hypertension is a rare but fatal disease, and current therapies are not curative and are associated with significant drawbacks. As part of a
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/18/2009
BAYLOR COLLEGE OF MEDICINE $549,624 Trans-NIH Recovery Act Research Support We propose to study the in-depth mechanism of this repression, and how this relates to SAFB1G??s role in breast tumorigenesis. We originally cloned SAFB1 as a transcriptional repressor, and it has since been implicated in a number of processes including National Institutes of Health 7/16/2009
CITY OF HOUSTON $547,246 ARRA - Immunization Houston will utilize American Recovery and Reinvestment funds in order to implement several activities that include immunizing vulnerable populations at non-traditional venues such as public health STDs, school-based vaccination events, seasonal influenza Centers for Disease Control and Prevention 9/15/2009
UNIVERSITY OF TEXAS M D ANDERSON $543,645 Trans-NIH Recovery Act Research Support The proposal seeks to develop the first meaningful objective radiographic parameter that correlates with the clinical symptoms of radiation pneumonitis (RP) as an imaging biomarker of RP. RP is the dose limiting toxicity in thoracic radiotherapy for lung National Institutes of Health 6/02/2009
TEXAS SOUTHERN UNIVERSITY (INC) $541,208 ARRA - Scholarships for Disadvantaged Students Scholarships for Disadvantaged Students Health Resources and Services Administration 9/03/2009
UNIVERSITY OF TEXAS M D ANDERSON $539,608 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $2,008,515 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $531,689 Trans-NIH Recovery Act Research Support The goal of this research is to identify novel susceptibility genes for lung cancer using a systematic genome- wide association-based approach. To achieve this goal, we are applying a two-stage design. This proposal builds upon an extensive resource of lu National Institutes of Health 9/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $526,400 Trans-NIH Recovery Act Research Support A strong body of work has implicated the cell surface urokinase receptor (u-PAR) in modulating tumor growth and progression. Elevated u-PAR levels yield increased growth while low u-PAR promotes tumor dormancy the latter protective against microenvironmen National Institutes of Health 6/10/2009
WILLIAM MARSH RICE UNIVERSITY $524,001 Trans-NIH Recovery Act Research Support Influenza A virus causes annual epidemics and is potential threat for widespread pandemics. The genome of influenza A virus consists of eight segments of (-)RNA that are encapsidated in distinct double-helical structures called the ribonucleoprotein (RNP)
This spending item is part of a $766,481 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $512,778 Trans-NIH Recovery Act Research Support This application addresses the Challenge Area 06 of 'Enabling Technologies and Prevention' and the specific Challenge Topic 06-HL-104 of 'enabling technologies involving the development of nanotools for pulmonary medicine, particularly aimed at safer and
This spending item is part of a $999,999 allocation. See details
National Institutes of Health 9/18/2009
BAYLOR COLLEGE OF MEDICINE $500,000 Trans-NIH Recovery Act Research Support Statement of Purpose (15 words): This instrument will help transform the way scientists from a broad range of disciplines conduct research to understand the molecular mechanisms of human diseases, including disease gene cloning, cancer, gene expression, s National Institutes of Health 6/10/2010
WILLIAM MARSH RICE UNIVERSITY $500,000 Trans-NIH Recovery Act Research Support Fluorescent microscopy has revolutionized modern biology. From calcium sensitive dyes that track the exquisite regulation of this second messenger to fluorescent fusion proteins that allow us to pinpoint the subcellular distribution of proteins, our abili National Institutes of Health 5/13/2010
UNIVERSITY OF HOUSTON SYSTEM $495,802 Trans-NIH Recovery Act Research Support The perception of form is one of the most basic functions of the visual system. Because motion and dynamic occlusions are ubiquitous in our environment, understanding how the human visual system computes the form of moving objects in the presence of occl National Institutes of Health 7/17/2009
TEXAS CHILDREN'S HOSPITAL $489,203 ARRA - Immunization Grant funds will provide for active surveillance of acute gastroenteritis in young children who are admitted or seen in the emergency department during the rotavirus season at Texas Children's Hospital. The Department of State Health Services and the hosp
This spending item is part of a $493,255 allocation. See details
Centers for Disease Control and Prevention 9/02/2009
BAYLOR COLLEGE OF MEDICINE $480,749 Trans-NIH Recovery Act Research Support PURPOSE: Enhancement of the capabilities of the NURSA to generate and disseminate nuclear receptor and coregulator datasets and methodologies of a more translational character. ABSTRACT: Define the temporal and spatial physiology of Nuclear Receptors
This spending item is part of a $3,184,099 allocation. See details
National Institutes of Health 9/21/2009
MEMORIAL HERMANN HEALTHCARE SYSTEM $479,550 ARRA - Health Information Technology Extension Program Texas Gulf Coast HITECH Extension Center--This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance and information on best practices to support a... Show more
This spending item is part of a $13,234,318 allocation. See details
Health and Human Services, Department of 3/31/2010
UNIVERSITY OF TEXAS M D ANDERSON $477,665 Trans-NIH Recovery Act Research Support It has been suggested that the small fraction of tumor cells capable of initiating local or distant recurrence exhibit properties of stem cells, and that identification and molecular characterization of putative cancer stem cells will lead to better outco
This spending item is part of a $535,374 allocation. See details
National Institutes of Health 9/15/2009
BAYLOR COLLEGE OF MEDICINE $459,538 Trans-NIH Recovery Act Research Support The current project addresses a key question in osteosarcoma research that has not been addressed before and attempts to develop a new mouse model for aneuploid osteosarcoma. Unstable chromosome number known as aneuploidy is a hallmark of pediatric osteos National Institutes of Health 9/18/2009
SOUTH CNTRL HOU COMM $458,600 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Capital Improvement Program This grant has been used to purchase a new EMR and Patient Management System for our FQHC. We have also purchased equipment needed to run the softwar. Health Resources and Services Administration 6/25/2009
WILLIAM MARSH RICE UNIVERSITY $457,500 Trans-NIH Recovery Act Research Support Coupled electron and proton transfer is recognized as the universal principle of primary energy conservation in respiration. Terminal respiratory oxidases are membrane-bound electron- transfer complexes that catalyze the reduction of oxygen to water and t National Institutes of Health 7/15/2009
GREATER HOUSTON HEALTH INFORMATION EXCHANGE $453,693 ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health ... Show more
This spending item is part of a $28,810,208 allocation. See details
Health and Human Services, Department of 3/15/2010
UNIVERSITY OF TEXAS M D ANDERSON $453,213 Trans-NIH Recovery Act Research Support In collaboration with scientists at the Unversity of Texas MD Anderson Cancer Center, we will test our immunotherapeutic approach to treating HPV related cancers in a non-human primate model. This study fulfills the premises of the Grand Opportunity Grant
This spending item is part of a $980,587 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF HOUSTON SYSTEM $450,000 Trans-NIH Recovery Act Research Support Bacterial resistance to antibiotics is rising at an alarming rate. Of particular concern is the prevalence of multidrug resistant Gram-negative bacteria (e.g., Pseudomonas aeruginosa), for which all available first-line antibiotics are ineffective. The National Institutes of Health 3/29/2010
UNIVERSITY OF HOUSTON SYSTEM $450,000 Trans-NIH Recovery Act Research Support Alcoholism and alcohol abuse is a major cause of death (4.5 percent of the US population) with an economic burden of 184 billion dollars/year in the US. Defining the target(s) and elucidating the molecular mechanism of its action is needed for effective p National Institutes of Health 4/13/2010
UNIVERSITY OF HOUSTON SYSTEM $450,000 Trans-NIH Recovery Act Research Support Title: Prostacyclin-secreting Cells as Therapy for Pulmonary Artery Hypertension Description: Pulmonary arterial hypertension is a rare but fatal disease, and current therapies are not curative and are associated with significant drawbacks. As part of a
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/18/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $449,695 Trans-NIH Recovery Act Research Support Oral cancer, largely oral squamous cell carcinoma (OSCC), is a global health problem afflicting close to 300,000 people each year. Despite significant advances in surgical procedures and treatment, the long-term prognosis for patients with OSCC remains po
This spending item is part of a $1,955,950 allocation. See details
National Institutes of Health 9/25/2009
EL CENTRO DEL CORAZON $447,855 ARRA Health Center Integrated Services Development Initiative[g1] The award was given to enable renovation of a facility to expand services, implementation of EHR and up date of HIT - a CIP grant Health Resources and Services Administration 6/25/2009
EL CENTRO DEL CORAZON $447,855 ARRA Health Center Integrated Services Development Initiative[g1] The award was for the renovation of a building adding 11 exam rooms and for implementation of EHR and HIT update. Health Resources and Services Administration 6/29/2009
WILLIAM MARSH RICE UNIVERSITY $432,302 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $2,008,515 allocation. See details
National Institutes of Health 9/30/2009
CHRISTUS HEALTH $430,000 ARRA - Health Information Technology Extension Program Texas Gulf Coast HITECH Extension Center--This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance and information on best practices to support a... Show more
This spending item is part of a $13,234,318 allocation. See details
Health and Human Services, Department of 3/31/2010
BAYLOR COLLEGE OF MEDICINE INC $429,750 Trans-NIH Recovery Act Research Support Purpose: To aquire state-of-the art flow cytometer. Abstract: Our research at Baylor College of Medicine requiring a four-laser LSRII flow cytometer will specifically study processes within cells allowing us to better understand stem cell therapies, a National Institutes of Health 4/28/2009
BAYLOR COLLEGE OF MEDICINE $428,940 Trans-NIH Recovery Act Research Support TRANSCRIPTOME AND EPIGENOME ANALYSIS OF HELPER T CELL SPECIFICATION AND PLASTICIT
This spending item is part of a $2,759,411 allocation. See details
National Institutes of Health 9/28/2009
FOURTH WARD CLINIC $426,505 ARRA Health Center Integrated Services Development Initiative[g1] To utilize the ARRA grant funds (CIP) for the purpose of purchasing and implementing an electronic medical record with a practice management system. The funds will cover most of the cost of the hardware, software and training needed t... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $423,500 Trans-NIH Recovery Act Research Support Vaccination for protection against sexually transmitted diseases such as acquired immunodeficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) infection should concentrate on inducing strong antigen-specific humoral and cellular immune re National Institutes of Health 5/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $423,036 Trans-NIH Recovery Act Research Support Exposure of men to gonadotoxic cancer therapeutic agents can severely impair spermatogenesis. Many of the radiotherapeutic and chemotherapeutic regimens may result in complete killing of the stem spermatogonia without a chance for endogenous restoration o National Institutes of Health 9/02/2009
BAYLOR COLLEGE OF MEDICINE $422,125 Trans-NIH Recovery Act Research Support This project studies the role of CXCL16 in the development of atherosclerosis. Despite considerable progress in understanding the role of inflammation in atherosclerosis, it remains unclear what mechanisms drive the inflammation and how it is regu National Institutes of Health 6/18/2009
UNIVERSITY OF HOUSTON SYSTEM $422,033 Trans-NIH Recovery Act Research Support The homeostatic balance between proliferation and apoptosis is essential for the intestinal epithelium to function as a physiological and structural barrier. Intestinal epithelial cells have a high rate of cell turnover accompanied by an equally high rate National Institutes of Health 4/11/2011
BAYLOR COLLEGE OF MEDICINE $421,982 Trans-NIH Recovery Act Research Support 'Medication development for MA dependence. abstract:N-acetyl-l-cysteine (NAC) treatment is associated with reduced susceptibility to reinstatement of cocaine-seeking behavior in rats (Baker et al 2002) and with reduced cue-induced craving in cocaine-depen National Institutes of Health 8/10/2009
BAYLOR COLLEGE OF MEDICINE $415,153 Trans-NIH Recovery Act Research Support More than 50% of male cancer patients subjected to cisplatin-based chemotherapy will suffer from long-term infertility. This is a significant concern because many of these patients are young men who survive their cancer and would hope to later reproduce. National Institutes of Health 9/02/2009
BAYLOR COLLEGE OF MEDICINE $413,468 ARRA - Strategic Health IT Advanced Research Projects (SHARP) This Strategic Health IT Advanced Research Projects (SHARP) Program seeks to support improvements in the quality, safety and efficiency of health care through advanced information technology.
This spending item is part of a $15,000,000 allocation. See details
Health and Human Services, Department of 3/19/2010
UNIVERSITY OF TEXAS M D ANDERSON $413,447 Trans-NIH Recovery Act Research Support The difficulty quitting and chronic relapse which characterize the experience of many smokers may be due in large measure to the adaptations in neural mechanisms regulating reward, affect, and goal- directed behavior that have taken place as a consequence
This spending item is part of a $434,487 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF HOUSTON SYSTEM $412,500 Trans-NIH Recovery Act Research Support Bacterial keratitis is a major cause of ocular surface morbidity that often leads to permanently compromised visual function, somethings to an extent that necessitates corneal transplantation to resture adequate vision. Often the bacterial strains that c National Institutes of Health 8/19/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $412,500 Trans-NIH Recovery Act Research Support The objective of this proposal is to produce a panel of stable conformational isomers of human a- synuclein (aSyn) for use as immunogens to develop immunotherapy of Parkinson disease (PD). Human a-Synuclein (a-Syn) is a recognized protein marker for the p National Institutes of Health 5/15/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $412,500 Trans-NIH Recovery Act Research Support We propose to test the hypothesis that catabolic antibodies play an important innate defense role in protecting against Staphylococcus aureus infections. S. aureus is an opportunistic pathogen that colonizes the skin (primarily the anterior nasal vestibul National Institutes of Health 8/11/2009
HOUSTON COMMUNITY HEALTH CENTERS INC $409,635 ARRA Health Center Integrated Services Development Initiative[g1] This is an application for a CIP grant to improve the infrastructure associated with three in-scope facilities that compose Houston Community Health Centers, Inc. (HCHC): Airline Children?s Clinic, Denver Harbor Family Medicine Clinic ... Show more Health Resources and Services Administration 6/25/2009
BAYLOR COLLEGE OF MEDICINE $408,750 Trans-NIH Recovery Act Research Support 'Apoptosis is an orderly process of cellular elimination, which ensures complete disassembly and disappearance of damaged cells. Recently the concept of apoptotic cell elimination was expanded and programmed cell death is no longer viewed as an individual National Institutes of Health 6/15/2009
PASADENA HEALTH CENTER, INC. $405,820 ARRA Health Center Integrated Services Development Initiative[g1] Award Name: Capital Improvement Program grant Purpose: This grant allows funding for projects that include IT/Equipment, Health Information Technology, Dental and Medical X-ray equipment. List the goals of the project and importance ... Show more Health Resources and Services Administration 6/25/2009
LEGACY COMMUNITY HEALTH SERVICES, INC. $405,782 ARRA Health Center Integrated Services Development Initiative[g1] Legacy Community Health Services (Legacy) has provided community based healthcare services to underserved Houstonians for more than 27 years. Legacy?s target population is comprised of uninsured, underinsured and low-income persons see... Show more Health Resources and Services Administration 3/27/2009
TEXAS A&M UNIVERSITY SYSTEM,THE $402,875 Trans-NIH Recovery Act Research Support We recently demonstrated that soon after Bacillus anthracis spores are delivered into mouse lungs significant quantities of these spores are found inside the lung epithelial cells. Here we hypothesize that this intracellular presence plays an important ro National Institutes of Health 5/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $402,590 Trans-NIH Recovery Act Research Support The vast majority of HIV-1 infections occur at mucosal surfaces in the body. There is therefore an immediate need for potent HIV vaccines that can provide barrier protection at mucosal surfaces. While there is this need,most HIV vaccines have been develop
This spending item is part of a $720,202 allocation. See details
National Institutes of Health 9/11/2009
UNIVERSITY OF TEXAS M D ANDERSON $401,940 Trans-NIH Recovery Act Research Support The lymphatic vasculature plays a critical role in the pathogenesis of many diseases including inflammatory disorders, lymphedema, tumor progression, and metastasis. More recently, the important role of lymphatic vessels in disease states such as tumor di National Institutes of Health 8/03/2009
UNIVERSITY OF TEXAS M D ANDERSON $400,400 Trans-NIH Recovery Act Research Support The proposed studies will test the overall hypothesis that TSLP is a master switch for developing and maintaining atopy and asthma. TSLP is a hematopoietic cytokine encoded on the human chromosome 5q22 cluster of Th2 cytokine genes, and in humans is produ
This spending item is part of a $579,499 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $399,090 ARRA - Public Health Traineeship Program This funding was given by HRSA as a supplement for a formula funded Public Health Trainee program award for the purpose of providing additional traineeships and scholarships to both new and currently enrolled students in Public Health. Health Resources and Services Administration 9/03/2009
SPRING BRANCH COMMUNITY HEALTH CENTER $391,855 ARRA Health Center Integrated Services Development Initiative[g1] The Capital Improvement Project funds have been fully utilized and project is complete. Project funds were utilized to renovate our main facility, add a satellite and add Electronic Medical Record system to our operations. Health Resources and Services Administration 6/25/2009
BAYLOR COLLEGE OF MEDICINE $383,750 Trans-NIH Recovery Act Research Support 'Infections associated with indwelling medical devices, particularly catheters account for about half of nosocomial infections in the United States. These infections prolong hospital stay and result in substantial morbidity and mortality. Bacterial coloni National Institutes of Health 6/04/2009
BAYLOR COLLEGE OF MEDICINE $383,750 Trans-NIH Recovery Act Research Support Modulation of conjunctival goblet cell differentiation by immunoregulatory cells: This project will investigate the role of local immunoregulatory pathways on conjunctival epithelial homeostasis and the response of the conjunctival epithelium to the desic National Institutes of Health 8/04/2009
BAYLOR COLLEGE OF MEDICINE $383,750 Trans-NIH Recovery Act Research Support Purpose. To elucidate molecular mechanisms involved in HIV Tat function. Abstract: The HIV-1 Tat protein is essential for viral replication and it acts to activate RNA polymerase II (RNAP II) elongation of the integrated provirus. To a considerable ext National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $380,606 Trans-NIH Recovery Act Research Support 1.0This application Abdominal Symptom Phenotype: Pathways to New Biomarkers (ASPPNB)is in response to RFA-OD-09-004, American Recovery and Reinvestment Act for research and infrastructure. This application is responsive to NINR priorities related to disco
This spending item is part of a $1,869,398 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS M D ANDERSON $376,129 Trans-NIH Recovery Act Research Support A tremendous amount of research energy has been dedicated to demonstrating the importance of genetic influences on developmental psychopathologies in children. To date a convincing argument can be made that all of the developmental psychopathologies are
This spending item is part of a $3,761,304 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $372,680 Trans-NIH Recovery Act Research Support Several randomized controlled trials have demonstrated that exercise can benefit cancer patients in terms of their physical functioning and symptoms. Few studies have included patients with advanced disease, a group that is living longer with their diseas National Institutes of Health 8/14/2009
UNIVERSITY OF TEXAS M D ANDERSON $371,635 Trans-NIH Recovery Act Research Support Pancreatic cancer is a serious health problem. In the United States alone, nearly 35,000 new cases are diagnosed annually and about same number of patients die of the disease. Difficulty in early diagnosis, rapid metastasis and intrinsic resistance to kno National Institutes of Health 5/15/2009
BAYLOR COLLEGE OF MEDICINE $371,470 Trans-NIH Recovery Act Research Support The goal is to develop a novel virus-like particle (VLP) stimulated dendritic cell (DC) immunotherapeutic vaccine for pancreatic cancer. This project is designed to test a central hypothesis that silencing the master immune negative regulator MSK (mitogen National Institutes of Health 5/14/2009
UNIVERSITY OF TEXAS M D ANDERSON $371,171 Trans-NIH Recovery Act Research Support This research will start to identify and break down racial and ethnic communications barriers and will serve as a model that could be implemented at other cancer centers and hospitals nationwide to improve minority participation in clinical trials. While
This spending item is part of a $4,180,489 allocation. See details
National Institutes of Health 9/27/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $370,500 Trans-NIH Recovery Act Research Support Lyme disease is the most prevalent tick-borne infection in North America and Eurasia and can cause long-term infections that affect the skin, joints, heart, and central nervous system. Thebacterium that causes Lyme disease (Borrelia burgdorferi) remains h National Institutes of Health 9/13/2010
UNIVERSITY OF TEXAS M D ANDERSON $369,994 Trans-NIH Recovery Act Research Support The goal of this research is to identify novel susceptibility genes for lung cancer using a systematic genome- wide association-based approach. To achieve this goal, we are applying a two-stage design. This proposal builds upon an extensive resource of lu National Institutes of Health 9/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $364,139 Trans-NIH Recovery Act Research Support Findings from the Human Genome Project highlight the intricacy of interactions between cell regulation, genes and proteins. It is generally understood that biological functions and biological activities are controlled by subsets of genes interacting with National Institutes of Health 9/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $364,000 Trans-NIH Recovery Act Research Support The survival of every species depends on the faithful inheritance of genetic information. Essential to this process are the accurate movement and positioning of chromosomes and plasmids to daughter cells at cell division. The ultimate goal of this proposa National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $355,897 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $354,033 Trans-NIH Recovery Act Research Support Before any cell divides to yield viable daughters, it must first separate its duplicated chromosomes and splitits cytoplasm between them. This fundamentally important event, cytokinesis, must occur at the correcttime, after chromosome segregation, and pla National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $353,442 Trans-NIH Recovery Act Research Support The primary goal of the research proposed in this competitive renewal application is to understand the role of Akt downstream signaling pathways in epithelial carcinogenesis. During the previous funding period, we discovered that Akt activation is an impo National Institutes of Health 5/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $353,156 Trans-NIH Recovery Act Research Support Hepatocellular carcinoma (HCC) develops synergistically in HCV-infected patients with alcoholism, and no treatments are available for this devastating complication. Our study reveals the role of TLR4-dependent Nanog+ cancer stem cells (CSCs) in liver onco
This spending item is part of a $1,946,907 allocation. See details
National Institutes of Health 9/28/2009
HEALTH CARE FOR THE HOMELESS HOUSTON $350,911 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Capital Improvement Program. This award is comprised of two parts. One is the EHR Enhancement and the other is for IT/Equipment only purchase. Healthcare for the Homeless - Houston has three aims 1) to upgrade the quality rep... Show more Health Resources and Services Administration 6/25/2009
HARRIS COUNTY HOSPITAL DISTRICT $346,985 ARRA Health Center Integrated Services Development Initiative[g1] Increased Demand for Services Performance Narrative ARRA G?? Increase Services to Health Centers Quarterly and Final Report April 10, 2011 Project update: Increased health center staff G?? As of March 26, 2011 Health Care For the H... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF TEXAS M D ANDERSON $346,304 Trans-NIH Recovery Act Research Support Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The LCMC member
This spending item is part of a $4,894,665 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $345,794 Trans-NIH Recovery Act Research Support Inappropriate exposure to environmental agents during critical, sensitive periods of development can reprogram target tissues via epigenetic mechanisms to increase the risk for disease later in adult life. The reproductive tract is particularly sensitive National Institutes of Health 8/15/2009
UNIVERSITY OF HOUSTON SYSTEM $341,934 Trans-NIH Recovery Act Research Support Nitric oxide (NO) is a cell signaling molecule that is involved in numerous biological processes. The Principal Investigator (PI) will look at the possible role of NO in fertility. Studies with rats have shown that NO has an effect on both reproduction National Institutes of Health 8/26/2010
UNIVERSITY OF TEXAS M D ANDERSON $340,626 Trans-NIH Recovery Act Research Support Asthma is characterized by airway obstruction, airway hyperresponsiveness (AHR) and airway inflammation. The medications used for control and acute relief of asthma may vary in effectiveness and produce serious side effects. Also, ~30% of asthma patient
This spending item is part of a $1,036,014 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $338,800 Trans-NIH Recovery Act Research Support How does exercise counteract stress-induced tumor growth? Increased physical activity following the diagnosis of cancer has been demonstrated to significantly reduce cancer recurrence. Furthermore, exercise has been demonstrated to have antidepressant eff National Institutes of Health 5/13/2009
UNIVERSITY OF TEXAS M D ANDERSON $333,047 Trans-NIH Recovery Act Research Support Obesity has increased dramatically over the past 30 years in the USA and has been associated with pancreatitis and pancreatic cancer, as well as other cancers. A potential mechanistic link between obesity and cancer susceptibility is insulin-like growth f
This spending item is part of a $693,163 allocation. See details
National Institutes of Health 5/07/2009
UNIVERSITY OF TEXAS M D ANDERSON $332,740 Trans-NIH Recovery Act Research Support The cellular immune system holds much potential for mediating antitumor responses in cancer patients. Melanoma is particularly appealing to study immunotherapy, since several melanoma-specific antigens recognized by T cells have been identified over the p National Institutes of Health 8/01/2009
WILLIAM MARSH RICE UNIVERSITY $328,067 Trans-NIH Recovery Act Research Support Adult stem cell based therapies (using a patient's own cells, not embryonic cells) have emerged as a promising approach in regenerative medicine. The ability to track transplanted stem cells after they are injected into the body is a crucial tool because
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $326,294 Trans-NIH Recovery Act Research Support This component supports a KL2 Scholar to develop special expertise in CER and provides 0.75 protected time, course work, and mentorship while conducting major CER. The candidates are Susan Wootten, M.D., Patricia Evans, M.D., and Claudia Pedroza, M.D. National Institutes of Health 9/23/2010
WILLIAM MARSH RICE UNIVERSITY $324,183 Trans-NIH Recovery Act Research Support Overall Goal:-Obtain maximum molecular information by Mass Spectrometry from a single 10 micron diameter cell. Ionwerks has created new classes of nanoparticulate (NP) matrices which can be localized in submonolayer amounts on or within the first several
This spending item is part of a $2,996,567 allocation. See details
National Institutes of Health 8/23/2010
UNIVERSITY OF TEXAS M D ANDERSON $320,000 Trans-NIH Recovery Act Research Support Near-infrared fluorescence (NIRF)-based optical imaging of human cancers has several advantages over standard imaging techniques in that it is extremely sensitive, inexpensive, and robust; involves no harmful radiation; and allows real-time visualization. National Institutes of Health 9/09/2009
UNIVERSITY OF TEXAS M D ANDERSON $318,098 Trans-NIH Recovery Act Research Support The primary goal of the research in this competitive renewal application is to understand the role of signal transducers and activators of transcription (Stats), particularly Stat3, in epithelial carcinogenesis. During the previous funding period, through National Institutes of Health 5/07/2009
UNIVERSITY OF TEXAS M D ANDERSON $308,380 Trans-NIH Recovery Act Research Support Abstract In reference to NOT-OD-09-058 (Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications), we submit this Competitive Revision to the parent grant entitled 'Tumor metastasis: Biobehavioral mechanisms National Institutes of Health 5/24/2010
UNIVERSITY OF TEXAS M D ANDERSON $308,000 Trans-NIH Recovery Act Research Support Cancer predisposition syndromes are autosomal dominantly inherited conditions in which the affected individuals have a high relative risk for developing cancer. PTEN and neurofibromatosis-2 (NF2) are tumor suppressors that are inactivated in both somatic National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS M D ANDERSON $308,000 Trans-NIH Recovery Act Research Support The University of Texas M. D. Anderson Cancer Center (MDACC) is a free-standing comprehensive cancer center within the University of Texas system. The mission of the MDACC is to eliminate cancer in Texas, the nation and the world through outstanding integ National Institutes of Health 9/22/2009
HOUSTON-GALVESTON AREA COUNCIL, THE $307,857 Aging Congregate Nutrition Services for States ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith-based settings.
This spending item is part of a $4,012,217 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF TEXAS M D ANDERSON $305,756 Trans-NIH Recovery Act Research Support This proposal builds on a rich resource of bladder cancer (BC) cases and controls derived from two ongoing BC studies at the University of Texas M.D. Anderson Cancer Center, and from two large independent U.S. BC studies - the New England BC Study and the National Institutes of Health 9/23/2009
BAYLOR COLLEGE OF MEDICINE $303,492 Trans-NIH Recovery Act Research Support This proposal is requesting funds to purchase a Thermo Electron Delta V Advantage Isotope Ratio Mass Spectrometer with a H/Device, a GasBench II, and the accompanied accessories. The Delta V mass spectrometer system will provide accurate and automated sta National Institutes of Health 4/08/2010
BAYLOR COLLEGE OF MEDICINE $300,000 Trans-NIH Recovery Act Research Support To purchase new equipment to be run by a new-?ly hired technician and provide pilot funds for novel GI-related projects. This AARA Administrative Supplement requests funding to enhance the ability of the Texas Medical Center Digestive Diseases Research Co National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $300,000 ARRA ? Equipment to Enhance Training for Health Professionals This one-year project entitled Enhancing Nurse Anesthesia Education through Simulation for Rural Populations will create model for effectively employing simulation technologies to prepare nurse anesthesia students for the role of safe and ... Show more Health Resources and Services Administration 9/08/2010
LONE STAR COLLEGE SYSTEM $297,499 ARRA ? Equipment to Enhance Training for Health Professionals Grant name: Equipment to Enhance Training for Health Professionals (EETHP) program - ARRA The purpose of this grant is to purchase equipment that will increase the quality of training of healthcare professionals. Lone Star College System... Show more Health Resources and Services Administration 9/03/2010
BAYLOR COLLEGE OF MEDICINE $296,926 Trans-NIH Recovery Act Research Support Purpose:The BCM-Emory Fragile X research center ARRA stimulus funds requested here will accelerate efforts to understand and treat these disorders through the study of patient symptoms and models of the diseases. Abstract: The BCM-Emory Fragile X Researc
This spending item is part of a $399,941 allocation. See details
National Institutes of Health 9/16/2009
BAYLOR COLLEGE OF MEDICINE $291,311 Trans-NIH Recovery Act Research Support We will develop high resolution CGH arrays to detect mutations on mouse chromosome 11 . In our parent grant, we propose to assign function to a number of genes on mouse chromosome 11 National Institutes of Health 8/27/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $290,035 Trans-NIH Recovery Act Research Support Retinopathy of prematurity (ROP) is a potentially blinding disease of premature infants in which retinal blood vessels fail to develop properly. A multicentered clinical trial (CRYO-ROP Study) sponsored by the National Eye Institute demonstrated that peri National Institutes of Health 8/12/2009
BAYLOR COLLEGE OF MEDICINE $289,704 Trans-NIH Recovery Act Research Support The award will provide for continuation of ongoing activities of the PPRU. The Supplemental Funding allows for the continuation and completion of ongoing PPRU projects begun during the past five National Institutes of Health 7/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $288,300 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $286,225 Trans-NIH Recovery Act Research Support The purpose of this award is to create new job and accelerate our research on SRC-1 and breast cancer. Our first task is to use the budget to hire a cancer research scientist with a citizenship of United States who will lose his job in August of 2009 due National Institutes of Health 8/28/2009
BAYLOR COLLEGE OF MEDICINE $281,332 Trans-NIH Recovery Act Research Support Ten to 17% of children between the ages of 4 and 16 years meet the criteria for recurrent abdominal pain (RAP). Of these, up to 68% meet the criteria for irritable bowel syndrome (IBS), which also affects 15 G?? 20% of adults. Up to 66% of RAP children de National Institutes of Health 9/18/2009
IHEALTH TRUST $277,500 ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health ... Show more
This spending item is part of a $28,810,208 allocation. See details
Health and Human Services, Department of 3/15/2010
BAYLOR COLLEGE OF MEDICINE $276,047 Trans-NIH Recovery Act Research Support Double-strand breaks (DSBs) are deleterious DNA lesions that occur spontaneously or are induced by chemicals or irradiation. DNA recombination is an essential process that repairs DSBs. There are two pathways of DSB repair, homologous recombination that u National Institutes of Health 8/13/2009
BAYLOR COLLEGE OF MEDICINE $275,628 Trans-NIH Recovery Act Research Support 'We are developing a casual game played on a cell phone to teach effective food parenting practices using simulated parent-child interaction sequences with feedback and goal setting.
This spending item is part of a $350,147 allocation. See details
National Institutes of Health 5/27/2009
CITY OF HOUSTON $275,384 Aging Home-Delivered Nutrition Services for States ARRA provided funding for Home-Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
This spending item is part of a $1,975,245 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF TEXAS M D ANDERSON $271,044 Trans-NIH Recovery Act Research Support Pancreatic cancer is a lethal disease as manifested by rapid progression and early formation of regional and distant metastasis, and resistance to conventional therapies. The underlying molecular basis of pancreatic cancer progression and metastasis is un National Institutes of Health 6/08/2009
WILLIAM MARSH RICE UNIVERSITY $269,106 Trans-NIH Recovery Act Research Support Cochlear outer hair cells enhance the sensitivity of mammalian hearing through active mechanical feedback powered by the membrane protein prestin. The long-term goal of our research efforts is to understand the mechanism by which prestin interacts with th
This spending item is part of a $296,552 allocation. See details
National Institutes of Health 7/15/2009
IHEALTH TRUST $268,676 ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health ... Show more
This spending item is part of a $28,810,208 allocation. See details
Health and Human Services, Department of 3/15/2010
BAYLOR COLLEGE OF MEDICINE $267,831 Trans-NIH Recovery Act Research Support Despite compelling evidence of the benefits of treatment, hypertension is controlled in less than 1/4th of US citizens. Inadequate blood pressure control results in excess cases of coronary artery disease, congestive heart failure, stroke and other diseas National Institutes of Health 8/10/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $264,000 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $396,000 allocation. See details
National Institutes of Health 9/24/2009
TEXAS SOUTHERN UNIVERSITY $262,336 DEVELOP, IMPLEMENT AND TEST STRATEGIES TO INCREASE THE ADOPTION AND DISSEMINATION OF EXISTING COMPARATIVE EFFECTIVENESS RESEARCH (CER)
This spending item is part of a $1,993,000 allocation. See details
Program Support Center 6/18/2010
BAYLOR COLLEGE OF MEDICINE $262,016 Trans-NIH Recovery Act Research Support This application addresses the NHLBI-RFA-OD-09-004 for Large-scale DNA Sequencing and Molecular Profiling of Well-phenotyped NHLBI Cohorts. We propose to establish a sequencing center to perform the production-level resequencing of exomes from 10,000 geno
This spending item is part of a $25,027,469 allocation. See details
National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $261,638 Trans-NIH Recovery Act Research Support Statement of Purpose (15 words): To enable large RAM genomic sequence analysis and meet the challenge of next-generation DNA sequencing. Abstract: High-throughput, short read DNA sequencing technologies have transformed sequence data production, necess National Institutes of Health 9/01/2010
BAYLOR COLLEGE OF MEDICINE $261,638 Trans-NIH Recovery Act Research Support Statement of Purpose (15 words): To enable large RAM genomic sequence analysis and meet the challenge of next-generation DNA sequencing. Abstract: High-throughput, short read DNA sequencing technologies have transformed sequence data production, necess National Institutes of Health 7/22/2010
UNIVERSITY OF HOUSTON SYSTEM $260,876 Trans-NIH Recovery Act Research Support Beta-adrenergic receptor (beta-AR) stimulation is the primary mechanism to increase the contractility of the heart, however chronic beta-AR stimulation, as occurs in heart failure (HF), results in reduced contractility. In heart cells, beta-AR stimulation National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $260,710 Trans-NIH Recovery Act Research Support Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, with an incidence of about 1 in 8,000 adults. The most common form of the disease, DM1, is caused by an expanded CTG repeat in the 3' UTR of the DMPK gene, and CUG repeat R
This spending item is part of a $2,922,996 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $258,180 The MD Anderson Cancer Center has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial cases. These cases are all primary and untreated. Th National Institutes of Health 4/27/2010
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $258,000 Trans-NIH Recovery Act Research Support Obesity is a major health problem in the United States. It increases the risk of insulin resistance (IR) and metabolic syndrome (MS), a cluster of cardiovascular disease (CVD) risk factors, and leads to additional pathologies, including non-alcoholic stea
This spending item is part of a $488,566 allocation. See details
National Institutes of Health 6/01/2010
WILLIAM MARSH RICE UNIVERSITY $257,379 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $256,481 Trans-NIH Recovery Act Research Support The additional aim will test if litter gender composition affects DNA methylation patterns in promoter regions of targeted genes in brain regions associated with stress responses (hippocampus) and drug reward (NAc; PFC) across the life span. Our hypothes National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $255,640 Trans-NIH Recovery Act Research Support (Also known as serine/threonine kinase 11, STK11) tumor suppressor is mutationally inactivated in Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterized by gastrointestinal polyps, mucocutaneous pigmentation, and a markedly increased r National Institutes of Health 5/08/2009
BAYLOR COLLEGE OF MEDICINE $254,000 Trans-NIH Recovery Act Research Support The current epidemic of Methicillin Resistant Staphylococcus aureus infection is a grand opportunity to apply new genetic methods to understanding this disease. There are multiple outcomes from MRSA infection, ranging from curable localized infection to d
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $253,451 Trans-NIH Recovery Act Research Support This is a competitive R25E renewal application for years 16 to 20 of The University of Texas M. D. Anderson Cancer Center Cancer Prevention Education: Student Research Experiences (the Program, www.cancerpreventiontraining.org). Since the beginning in 199 National Institutes of Health 9/15/2009
PRAIRIE VIEW A & M UNIVERSITY $250,996 ARRA - Scholarships for Disadvantaged Students ARRA - Scholarships for Disadvantaged Students - The focus of this project is to increase the recr... Show more Health Resources and Services Administration 6/14/2010
BAYLOR COLLEGE OF MEDICINE $250,880 Trans-NIH Recovery Act Research Support Comparative analysis of ataxia transcriptomics; ABSTRCT - This administrative supplement application is to carry out a transcriptome analysis of the SCAs models simultaneously to the genetic modifier work proposed in the original application. Specifically National Institutes of Health 9/28/2009
MOTHERLAND INC $250,000 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Capital Improvement Program Health Resources and Services Administration 6/25/2009
HOUSTON AREA COMMUNITY SERVICES, INC $250,000 ARRA Health Center Integrated Services Development Initiative[g1] CIP funds allow HACS to purchase and implement hardware and practice management/electronic health record software. These capabilities reduce non value added steps within the clinical process flow by allow providers and patients to hav... Show more Health Resources and Services Administration 6/25/2009
HOUSTON, CITY OF $250,000 Trans-NIH Recovery Act Research Support The Gulf Coast Transdisciplinary Research Recovery Center for Community Health brings together outstanding academic and public health institutions and centers as a Consortium. The Consortium will coordinate new research studies and projects with existing
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $246,751 Trans-NIH Recovery Act Research Support SPORE IN MELANOMA National Institutes of Health 9/09/2009
UNIVERSITY OF HOUSTON SYSTEM $246,672 Trans-NIH Recovery Act Research Support The objective of this request for an administrative supplement to 2 P50 HD052117-03, Texas Center for Learning Disabilities, to take advantages of unique opportunities to accelerate the tempo of the science of this synergistic, multi-disciplinary research
This spending item is part of a $363,777 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $244,686 Trans-NIH Recovery Act Research Support The ability of individual cells to communicate with each other is a fundamental property that allows them tocoexist in a context of multicellular organisms. Nitric oxide (NO) is one of the signaling molecules used tocommunicate with adjacent cells. A spec National Institutes of Health 7/15/2009
UNIVERSITY OF TEXAS M D ANDERSON $243,158 Trans-NIH Recovery Act Research Support The efficacy of treatment for non-small cell lung cancer (NSCLC) has improved only marginally over the past few decades. Chemoradiotherapy continues to have a narrow therapeutic index, and response rates are unpredictable, even after controlling for the k National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $242,962 Trans-NIH Recovery Act Research Support Special mechanisms of mutation are induced in bacteria and yeasts under growth-limiting stress causing genetic instability, and occasionally, adaptive mutations that may speed evolution. These stress-induced mutation mechanisms may provide superior models National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $240,969 Trans-NIH Recovery Act Research Support 'Statement of Purpose: To incorporate visual aids into science lectures developed by post-docs for undergraduate courses National Institutes of Health 7/31/2009
BAYLOR COLLEGE OF MEDICINE $238,220 Trans-NIH Recovery Act Research Support The purpose of this study is to understand how protein phosphatases regulate functions of blood cells called platelets with the long term goal of discovering new therapeutic targets for anti-thrombotic therapy. In particular, this supplement will examine National Institutes of Health 8/01/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH $237,373 Trans-NIH Recovery Act Research Support NTDs are a group of common, structural malformation that is associated with excess morbidity and mortality. A specific etiologic agent(s) cannot be identified in the majority of individuals with NTDs, and in this group of patients the condition is believe National Institutes of Health 4/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $235,750 Trans-NIH Recovery Act Research Support Cell-based immunotherapies hold great promise for treatment of malignancies, yet they are among the greatest challenges to develop and implement in modern medicine. There are typically no or few markers such as distinct clinical features, specific morphol National Institutes of Health 1/26/2010
WILLIAM MARSH RICE UNIVERSITY $234,951 Trans-NIH Recovery Act Research Support We propose to study membrane-active proteins and peptides that cause configurational changes in cell membranes, including pore formation and membrane fusion. Pore-forming peptides are animals' (including human's) gene-encoded innate antimicrobials that ki National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $233,737 Trans-NIH Recovery Act Research Support AKAPs had originally been thought of as anchoring the cAMP-dependent protein kinase A (PKA), to downstream targets of cAMP/PKA actions. However, in recent studies we have found that several isoforms of the enzyme that produces cAMP, adenylyl cyclase (AC) National Institutes of Health 9/25/2009
WILLIAM MARSH RICE UNIVERSITY $230,916 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
BAYLOR COLLEGE OF MEDICINE $230,250 Trans-NIH Recovery Act Research Support The overall goal of this competitive revision is a rigorous evaluation of the potential of engineered cocaine hydrolases alone and in combination with antibodies to ameliorate cocaine toxicity and cocaine abuse by preventing cocaine access to targets. Our
This spending item is part of a $732,603 allocation. See details
National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $220,647 Trans-NIH Recovery Act Research Support During the funding of the current R-01, our team made 4 discoveries related to human and mouse somatostatin receptor subtype five (hSSTR5, mSSTR5) and pancreatic duodenal homeobox-1 (PDX-1) that are highly translatable for patients suffering with islet ne National Institutes of Health 6/17/2010
TEXAS A&M UNIVERSITY SYSTEM,THE $219,472 Trans-NIH Recovery Act Research Support Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estrogen recept National Institutes of Health 9/01/2009
BAYLOR COLLEGE OF MEDICINE $216,878 Trans-NIH Recovery Act Research Support Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, with an incidence of about 1 in 8,000 adults. The most common form of the disease, DM1, is caused by an expanded CTG repeat in the 3' UTR of the DMPK gene, and CUG repeat R
This spending item is part of a $2,922,996 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $214,286 Trans-NIH Recovery Act Research Support Control of blood flow in the brain by vascular endothelial cells Adenosine triphosphate (ATP) is a potent regulator of vascular tone in the cerebral circulation. This physiological agonist is r National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $213,003 Trans-NIH Recovery Act Research Support Detrmine how Caicua modifies the course of SCA1 and to uncover the molecular functions of Ataxin1. ABSTRACT: Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disorder caused by expansion of a CAG repeat that encodes glutamine in Ataxin-1. Our National Institutes of Health 8/20/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $209,894 Trans-NIH Recovery Act Research Support Patients with acute coronary syndromes (ACS) who are diagnosed with major depression are at greater risk for subsequent major adverse coronary events (MACE). Major depression is associated with increased inflammatory protein levels, but only in certain in National Institutes of Health 7/20/2009
BIOTEX, INC. $208,913 Trans-NIH Recovery Act Research Support The primary project award revolves around an exciting marriage of bioinformatics, molecular biology, and engineering and results in the ability to discriminate (genotype) bacteria (and more recently viruses and fungi) at the species and strain level in a National Institutes of Health 4/19/2010
EL CENTRO DEL CORAZON $208,619 ARRA Health Center Integrated Services Development Initiative[g1] The grant was to increase access to service through expansion of hours and additional provider Health Resources and Services Administration 3/27/2009
FOURTH WARD CLINIC $208,303 ARRA Health Center Integrated Services Development Initiative[g1] Hiring additional Family Medicine Provider and support staff with the intention to provide primary healthcare to the low income/uninsured of our targeted service area. Outcome to be primary care to approximately 1200 patients providing... Show more Health Resources and Services Administration 3/27/2009
BAYLOR COLLEGE OF MEDICINE $208,180 Trans-NIH Recovery Act Research Support The purpose of this grant is to develop a mouse model of pacing-induced chronic AF to elucidate the contribution of calcium channels in chronic atrial fibrillation. Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting about 2.5 millio National Institutes of Health 7/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $207,547 Trans-NIH Recovery Act Research Support The central goal of this GO RC2 application is to leverage the collective resources of three institutions (VCU/Massey Cancer Center, MD Anderson Cancer Center, H. Lee Moffitt Cancer Center) and various associated support mechanisms (i.e., R01, P01, N01, a
This spending item is part of a $1,181,792 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $207,468 Trans-NIH Recovery Act Research Support Among the billions of neurons and glia in the vertebrate central nervous system (CNS) is a rich milieu of extracellular matrix (ECM) proteins. Most CNS cells interact with ECM components via members of the integrin family of cell surface adhesion receptor National Institutes of Health 8/21/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $207,396 Trans-NIH Recovery Act Research Support The Division of Biostatistics at the University of Texas Health Science Center at Houston (UTHSCH) will establish a pre-doctoral training in Biostatistics, by strengthening the links between the PhD degree programs in Biostatistics and the Human Genetics National Institutes of Health 7/31/2009
UNIVERSITY OF TEXAS M D ANDERSON $206,014 Trans-NIH Recovery Act Research Support This program is comprised of four highly interactive projects from Baylor College of Medicine (BCM) and M.D. Anderson Cancer Center (MDACC) in the Texas Medical Center (TMC) in Houston that focus on different aspects of the regulation of self-renewal and
This spending item is part of a $1,261,211 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $204,219 Trans-NIH Recovery Act Research Support Cardiolipin (CL) is an essential phospholipid for normal mitochondrial energy metabolism so that physiological and pathological perturbations in its levels result in alterations in the structure, function and assembly of mitochondria. CL is an integral pa National Institutes of Health 7/31/2009
UNIVERSITY OF TEXAS M D ANDERSON $203,365 Trans-NIH Recovery Act Research Support G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors, and play an important role in regulating cell survival and proliferation. They transduce environmental signals across the cytoplasm membrane through their ability to National Institutes of Health 9/25/2009
PASADENA HEALTH CENTER, INC. $201,419 ARRA Health Center Integrated Services Development Initiative[g1] American Recovery and Reinvestment Act (A.R.R.A.)-Increase Services to Health Centers (I.S.H.C.) Goal: The grant goal is to increase the number of patients seeking medical services from the health center. Purpose: The grant purpose i... Show more Health Resources and Services Administration 3/26/2009
FAIRWAY MEDICAL TECHNOLOGIES, INC. $199,998 Trans-NIH Recovery Act Research Support Project Title: Optoacoustic imaging enhanced by gold nanorods Supplemental funding will accelerate the development and market potential for a laser optoacoustic imaging system with enhanced sensitivity and resolution that uses a novel optoacoustic contras National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $199,884 Trans-NIH Recovery Act Research Support The project entails stereologic validation of a murine model of traumatic brain injury based upon MRI changes in brain-injured children and testing the efficacy of matrix metalloproteinase inhibitor in supporting structural recovery in the animal model.
This spending item is part of a $424,704 allocation. See details
National Institutes of Health 8/04/2009
BAYLOR COLLEGE OF MEDICINE $199,550 Trans-NIH Recovery Act Research Support Study the consequences of loss of MeCP2 function in cholinergic neurons. ABSTRACT: Rett Syndrome (RTT) is a devastating neurological disorder characterized by autistic features, cognitive impairments, motor abnormalities, seizures, and autonomic dysfunct National Institutes of Health 8/14/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $199,047 Recovery Act Comparative Effectiveness Research - AHRQ The STONE study, a multi-center randomized controlled trial (RCT), is a comparative effectiveness trial of three different imaging strategies in patients with suspected urolithiasis (kidney stones), seen in the Emergency Department. The study fo... Show more
This spending item is part of a $9,154,210 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $198,180 Trans-NIH Recovery Act Research Support Almost two million people sustain traumatic brain injury each year in the United States alone, with most reporting deficits in working memory. Working memory involves the 'online' storage of information necessary for performing cognitive operations. The p National Institutes of Health 8/13/2009
BAYLOR COLLEGE OF MEDICINE $198,124 Trans-NIH Recovery Act Research Support EMAN is a software suite for two and three dimensional image processing of transmission electron microscopy data. Its original design was specifically to perform the compuations required for a technique known as single particle reconstruction. This techni National Institutes of Health 9/11/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $197,822 Trans-NIH Recovery Act Research Support In the visual system, the information transmitted from the retina is analyzed and transformed by the visual cortex at multiple stages to construct an internal representation of the environment. It has long been suggested that the visual cortex is a passiv National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M D ANDERSON $197,325 Trans-NIH Recovery Act Research Support Our long term objectives are to understand the biochemical mechanisms that cause the feedback inhibition of hormonal or drug stimulation of the 22-adrenergic receptor (22AR) that mediates several important components of the 'fight-or-flight' response thro
This spending item is part of a $835,037 allocation. See details
National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $194,960 We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr
This spending item is part of a $1,627,009 allocation. See details
National Institutes of Health 9/27/2010
BAYLOR COLLEGE OF MEDICINE $191,800 Trans-NIH Recovery Act Research Support The purpose of this research is to identify a novel signaling pathway down stream of epithelial basolateral junctions that suppresses invasion and metastasis. National Institutes of Health 8/27/2009
HEALTH CARE FOR THE HOMELESS HOUSTON $188,036 ARRA Health Center Integrated Services Development Initiative[g1] In the application for Increased Demand for Services (IDS) funding, Healthcare for the Homeless - Houston (HHH) proposed three strategies for expanding access to primary care services and increased capacity at the Cathedral Clinic: 1)... Show more Health Resources and Services Administration 3/27/2009
BAYLOR COLLEGE OF MEDICINE $186,555 Trans-NIH Recovery Act Research Support This project will accelerate the progress of the funded research, increase the focus on a common vistibular disorder, increase the statistical power for some experiements of the parent grant for some experiments, ask a clinical question that may increase National Institutes of Health 9/17/2009
SOUTH CNTRL HOU COMM $186,262 ARRA Health Center Integrated Services Development Initiative[g1] ARRA-INCREASE SERVICES TO HEALTH CENTERS Health Resources and Services Administration 3/27/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $185,554 Trans-NIH Recovery Act Research Support This funding is provided for immediate hiring of a postdoctoral fellow/research associate trained in computational biology and image processing, 50% support for the current part-time research assistant plus essential equipment for the prime award. This National Institutes of Health 2/24/2010
BAYLOR COLLEGE OF MEDICINE $184,220 Trans-NIH Recovery Act Research Support Adult stem cells are present in many tissues and replenish the cellular constituents of those tissues throughout life. Recently, evidence has accumulated that at least under some conditions, progeny of adult stem cells can generate cells outside their tis National Institutes of Health 9/28/2010
UNIVERSITY OF HOUSTON SYSTEM $181,800 Trans-NIH Recovery Act Research Support The goal of the parent program is to begin development of electromagnetic sensors to detect abnormalities in mitochondrial metabolism that lead to type 2 diabetes and cardiovascular disease in obese patients. The sensors measure the responses (impedance National Institutes of Health 9/03/2009
SPRING BRANCH COMMUNITY HEALTH CENTER $181,501 ARRA Health Center Integrated Services Development Initiative[g1] The IDS funds have enabled the health center to increase the number of services provided to this medically underserved area. Health Resources and Services Administration 3/27/2009
UNIVERSITY OF TEXAS M D ANDERSON $181,006 Trans-NIH Recovery Act Research Support Great effort has been made in developing tumor-targeted gene delivery, but no attention has been given to targeting the therapeutic gene products that are transcribed and translated from genes transfected in normal tissues into tumors. Targeting gene prod National Institutes of Health 7/02/2010
HOUSTON COMMUNITY HEALTH CENTERS INC $181,000 ARRA Health Center Integrated Services Development Initiative[g1] This is an application for an Increased Demand for Services grant for Houston Community Health Centers, Inc. (HCHC). Through this application, HCHC will retain our dentist by utilizing IDS funding to cover all of salary for first twel... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $180,000 Trans-NIH Recovery Act Research Support In the United States alone, approximately 500,000 deaths will result from rupture of plaques considered 'insignificant' on an angiographic evaluation. Available screening and diagnostic methods are insufficient to identify possible victims before the even
This spending item is part of a $1,429,601 allocation. See details
National Institutes of Health 9/15/2009
BAYLOR COLLEGE OF MEDICINE $179,595 Trans-NIH Recovery Act Research Support We are submitting this application in response to the Recovery Act Administrative Supplement (NOT-OD-09-056) to the parent grant RO1 AG032135 entitled G?Epigenetic Regulation of Cell and tissue AgingG? (09/30/2007-08/31/2012. The objective of the parent g National Institutes of Health 9/17/2009
BAYLOR COLLEGE OF MEDICINE $178,420 Trans-NIH Recovery Act Research Support Purpose: To understand and prevent seizure-induced learning and memory deficits in children with severe epilepsy. Abstract: The studies proposed in our original application are based on the premise that recurring seizures in early-life contribute to cog National Institutes of Health 9/25/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $177,992 Trans-NIH Recovery Act Research Support When computerized provider order entry (CPOE) is coupled with real-time computer-based decision support (CDS), medical errors decrease and costs can drop because clinicians can be alerted to potential errors or guided to select lower cost medications and
This spending item is part of a $1,491,183 allocation. See details
National Institutes of Health 9/03/2009
UNIVERSITY OF TEXAS M D ANDERSON $177,832 Trans-NIH Recovery Act Research Support Proteins play major roles as biological effectors and diagnostic markers. One level of its complexity is due to the post-translational modifications that cannot be detected at the genome level, which makes it desirable to measure proteins directly. Recent
This spending item is part of a $382,368 allocation. See details
National Institutes of Health 6/05/2009
BAYLOR COLLEGE OF MEDICINE $176,495 Trans-NIH Recovery Act Research Support This supplement will allow for replacement of aging equipment and purchase of new equipment that will significantly improve the quality of research, and has allowed retention of 2 employees. The main goal of the current P01 proposal, which is in its 28th National Institutes of Health 9/07/2009
BAYLOR COLLEGE OF MEDICINE $173,920 Trans-NIH Recovery Act Research Support The long-term goal of this BRP project is to engineer hematopoietic bone ex vivo to provide synthetic organ based therapies for disorders of both bone and hematopoiesis. Our overarching hypotheses are that the steps that lead to bone formation and the est National Institutes of Health 7/15/2009
BAYLOR COLLEGE OF MEDICINE $173,000 The purpose of this task order is to support various VRC Universal Influenza studies. Specifically,the EMMES Corporation will provide all necessary technical, clinical, and management services in order to support four phase-I clinical trials (2 adult,2 pe
This spending item is part of a $8,654,779 allocation. See details
National Institutes of Health 9/30/2010
BAYLOR COLLEGE OF MEDICINE $168,956 Trans-NIH Recovery Act Research Support This application addresses the NHLBI-RFA-OD-09-004 for Large-scale DNA Sequencing and Molecular Profiling of Well-phenotyped NHLBI Cohorts. We propose to establish a sequencing center to perform the production-level resequencing of exomes from 10,000 geno
This spending item is part of a $25,027,469 allocation. See details
National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $168,823 Trans-NIH Recovery Act Research Support To determine the role of single-strand break repair in CAG repeat instability in human cells and mice. ABSTRACT The overall goal of our studies is to elucidate the mechanisms responsible for repeat expansions in humans. Our basic approach is to combine th National Institutes of Health 8/31/2009
UNIVERSITY OF HOUSTON SYSTEM $168,750 Trans-NIH Recovery Act Research Support The proposed project is designed to uncover the neural correlates of processing two languages as bilinguals transition from novice to intermediate L2 speakers in early childhood. To achieve this, the proposed project will use Near Infrared Spectroscopy ( National Institutes of Health 9/24/2010
UNIVERSITY OF HOUSTON SYSTEM $165,271 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (06) Enabling Technologies and Specific Challenge Topic, 06-AG-101: Neuroscience Blueprint: Development of non-invasive imaging approaches or technologies that directly assess neural activity. As the title o
This spending item is part of a $806,619 allocation. See details
National Institutes of Health 9/24/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $165,077 Trans-NIH Recovery Act Research Support Funds from this administrative supplement are being used to support senior postdoctoral fellow Rongmin Xia, as proposed in the supplement application. Dr. Xia has been trained on the use of the ExAblate 2000 (Insightec, Inc.) to conduct and support studi National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $165,000 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Are (06) Enabling Technologies and Specific Challenge Topic 06-CA-106 Data integration and visualization methods and tools. Prostate cancer is a highly prevalent disease in older men of the Western world, whose i
This spending item is part of a $998,992 allocation. See details
National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $162,354 Trans-NIH Recovery Act Research Support Funding for an administrative supplement is requested to carry out next generation sequencing of regions containing nonsyndromic hearing impairment (NSHI) loci in order to identify the phenotype causing gene. The last specific aim (3) of the parent grant National Institutes of Health 7/17/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $162,098 Trans-NIH Recovery Act Research Support Supplement to a primary grant, this initiative involves multiple institutions & addresses 3 G?bullet pointG? topics specified in the RFA: 1) CER skills for diverse health care researchers; 2) CER methodology skills development by economists, quality impro
This spending item is part of a $164,258 allocation. See details
National Institutes of Health 9/23/2010
BAYLOR COLLEGE OF MEDICINE $161,313 Trans-NIH Recovery Act Research Support This project aims to understand the mechanisms how immune complex-mediated signals modulate immunity and overcome age-associated immune deficiency. The success of this project will lead to a novel vaccination strategy to provide better protection to immun National Institutes of Health 9/13/2010
BAYLOR COLLEGE OF MEDICINE $160,514 Trans-NIH Recovery Act Research Support Two-photon confocal microscopy to study in vivo the biophysical implementation of multiplication and invariance. We propose to construct a two-photon confocal microscope to study synaptic integration in vivo in a visual neuron that detects impending colli National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $160,358 Trans-NIH Recovery Act Research Support Administrative Supplement: The intent of this supplemental request is to enhance the ability of the Dan L. Duncan Cancer Center (DLDCC) clinical investigators to enroll patients in clinical trials at an additional venue and provide support to a post-doct National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $159,817 Trans-NIH Recovery Act Research Support A major problem currently facing pediatric urology involves the diagnosis of disorders in genital and urinary tract development. Alththough much of the current diagnosis is descriptive (i.e. cyptorchidism: a failure of the testis to descend),the molecula National Institutes of Health 11/28/2009
CITY OF HOUSTON $159,215 ARRA - Immunization The Houston Department of Health and Human Services (HDHHS) received onetime funding from the Centers for Disease Control and Prevention for Evaluation of Meningococcal Conjugate Vaccine and other High-Priority Vaccine Preventable Diseases. It is estimate Centers for Disease Control and Prevention 9/03/2009
BAYLOR COLLEGE OF MEDICINE $156,218 Trans-NIH Recovery Act Research Support 1.0This application Abdominal Symptom Phenotype: Pathways to New Biomarkers (ASPPNB)is in response to RFA-OD-09-004, American Recovery and Reinvestment Act for research and infrastructure. This application is responsive to NINR priorities related to disco
This spending item is part of a $1,869,398 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS M D ANDERSON $154,779 Trans-NIH Recovery Act Research Support DNA damage and repair are fundamental to human health and disease. The long-term objectives of this application are to: expand our understanding of the role of DNA helical distortions in DNA damage recognition and processing; determine the factors influen
This spending item is part of a $294,823 allocation. See details
National Institutes of Health 8/10/2009
UNIVERSITY OF TEXAS M D ANDERSON $154,000 Trans-NIH Recovery Act Research Support Layman's abstract: Women with a history of preeclampsia in pregnancy are at reduced risk of breast cancer, especially those who delivered a son, not a daughter, from the pregnancy. Why is this so? We compare hormones in the blood of a group of women who h National Institutes of Health 7/16/2009
UNIVERSITY OF TEXAS M D ANDERSON $154,000 Trans-NIH Recovery Act Research Support Invasive aspergillosis (IA) is an important cause of respiratory and disseminated infection in immunocompromised patients, and the most common cause of infectious pneumonic mortality in recipients of hematopoietic stem cell transplants. Mortality from IA National Institutes of Health 8/01/2009
BAYLOR COLLEGE OF MEDICINE $153,500 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Baylor College of Medicine (Baylor) is applying for a Clinical Trials Unit (CTU) in response to NIH RFA-AI-05-002 Units for HIV/AIDS Clinical Trials Networks. Baylor (presently Pediatric AIDS Clinical Trials Group [PAC National Institutes of Health 9/13/2010
UNIVERSITY OF TEXAS M D ANDERSON $152,360 Trans-NIH Recovery Act Research Support The overall goal of this project is to conduct comparative effectiveness research on breast cancer imaging modalities and strategies to inform evidence gaps on how to optimize breast cancer screening in community practice. The Breast Cancer Surveillance C
This spending item is part of a $3,992,841 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $151,419 Trans-NIH Recovery Act Research Support Signaling transduction pathways and networks have recently proven to be attractive targets for cancer therapy. Gleevac, herceptin (TM), C225, Irressa, and CCI779 have all induced remarkable, non-toxic responses in a subset of patients where abnormalities National Institutes of Health 9/01/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $150,621 Trans-NIH Recovery Act Research Support MITOCHONDRIAL GENETIC DETERMINANTS OF HUMAN PARTURITION AND PRETERM BIRTH The processes underlying human parturition and etiology of preterm birth are not well-understood. There has been an intense focus in recent years on studies of the complex interact
This spending item is part of a $500,001 allocation. See details
National Institutes of Health 9/30/2009
HOUSTON-GALVESTON AREA COUNCIL, THE $150,270 Aging Home-Delivered Nutrition Services for States ARRA provided funding for Home-Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound.
This spending item is part of a $1,975,245 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $150,000 Trans-NIH Recovery Act Research Support Proton magnetic resonance spectroscopic imaging (MRSI) allows the in vivo determination regional distribution of various neurochemicals. The pathologic specificity and inherently quantitative information provided by MRSI should help understand the mechani National Institutes of Health 5/14/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $150,000 Trans-NIH Recovery Act Research Support The primary goal of this project is to reverse-engineer the interplay of gene variation (in candidate genes influencing renal tubular sodium transport and involved in renin-angiotensin-aldosterone system) and other variables contributing to the interindiv National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $150,000 Trans-NIH Recovery Act Research Support The genetic variability and Individual variations in immune status dictate responses to vaccinations, infections, and contribute to disease severity. The sequencing of the human genome and generation of the Haplotype Map now enables a mechanistic understa
This spending item is part of a $4,456,091 allocation. See details
National Institutes of Health 7/12/2010
BAYLOR COLLEGE OF MEDICINE $149,952 Trans-NIH Recovery Act Research Support The Liver Center at Texas Children's Hospital/Baylor College of Medicine (TCH/BCM) has been an active participant in BARC and CLiC, and is excited by the opportunity to continue participation. The overarching aims of this Center are to help advance the cl National Institutes of Health 3/11/2010
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $149,704 Trans-NIH Recovery Act Research Support Dramatic advancements in nanomagnetic sensor technology, driven by the needs of magnetic data storage industry, have now brought us disk drives with magnetic read heads addressing features of less than 80nm across, at a wholesale cost of about
This spending item is part of a $961,864 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $149,562 Trans-NIH Recovery Act Research Support Sequencing of the human genome and those of other organisms has revealed that a large percentage of pre-mRNAs are spliced in multiple patterns to produce mRNAs encoding distinct proteins. Although alternate splicing is widespread and must regulate the exp National Institutes of Health 1/29/2010
WILLIAM MARSH RICE UNIVERSITY $148,578 Trans-NIH Recovery Act Research Support Recent advances in confocal microscopy have demonstrated the potential of optical imaging to provide molecular images with sub-cellular resolution. In this proposal, we extend our work in high resolution confocal microscopy, based on a much simpler altern National Institutes of Health 8/07/2009
APOCELL, INC. $148,500 Phase I/II Clinical Trials and Pharmacodynamics NCIG??s Division of Cancer Treatment and Diagnosis (DCTD), under the umbrella of the American Recovery and Reinvestment Act of 2009 (ARRA), is requesting support for several new and expanded initiatives. The
This spending item is part of a $10,200,000 allocation. See details
National Institutes of Health 2/04/2010
BAYLOR COLLEGE OF MEDICINE $145,768 Trans-NIH Recovery Act Research Support [Role of c-Cbl in IL-12 production in genetically enhanced DCs.] Dendritic cells (DCs) have been used in countless clinical trials for cancer. Nevertheless, clinical responses remain modest, possible National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $145,546 Trans-NIH Recovery Act Research Support The purpose of this project is to define the molecular mechanisms of Cytochrome P4501A1 expression by polyclcyclic aromatic hydrocarbons (PAHs), in relation to carcinogenesis. Polycyclic aromatic hydrocarbons (PAHs) are present in cigarette smoke, particu National Institutes of Health 9/14/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $144,638 Trans-NIH Recovery Act Research Support We propose to develop an integrated computational system to track and analyze neuronal dendrites and spines observed in 3D time-lapse optical microscopy and manage all the data. The proposed work will overcome one barrier in neuroscience research, i.e.,la National Institutes of Health 9/03/2009
UNIVERSITY OF TEXAS M D ANDERSON $144,201 Trans-NIH Recovery Act Research Support Chronic lymphocytic leukemia (CLL) is a malignant B cell lymphoproliferative disorder and is most common in Caucasians, with a lifetime risk of 1 in 200. It has been known for decades that a genetic component affects CLL risk, with the risk of CLL on the
This spending item is part of a $616,035 allocation. See details
National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $141,442 Trans-NIH Recovery Act Research Support We are requesting Recovery Act (ARRA) Administrative Supplement for the parent grant R37 AI36040 under the notice number NOT-OD-09-056. This parent MERIT grant is in its seventh year with 3 more years. The requested supplement is for (1) purchasing an HPL National Institutes of Health 8/30/2010
BAYLOR COLLEGE OF MEDICINE $140,160 Trans-NIH Recovery Act Research Support This project is focused on elucidating molecular mechanisns of skeletal abnormalities in tricho-rhino-phalangeal syndrome.Mutations of the human TRPS1 gene cause a dominantly inherited skeletal dysplasia tricho-rhino-phalangeal syndrome (TRPS). Although National Institutes of Health 6/10/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $139,734 Trans-NIH Recovery Act Research Support One of the major challenges of modern medicine is the development of novel approaches for the efficient delivery of therapeutics and molecular specific treatment of pathology that can be carried out under imaging guidance and monitoring. Recent advances i National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $138,970 Trans-NIH Recovery Act Research Support Purpose: to validate and to measure N-nitroso compound intake in the total US population and by ethnic group and personal factors ABSTRACT: This application is a formative step towards assessing dietary intake of N-nitroso compounds in populations to National Institutes of Health 6/01/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $138,600 Trans-NIH Recovery Act Research Support The capacity for tissue repair is a fundamental property of multicellular organisms that is often critical for survival. Despite its biological and clinical importance, the signals that initiate and terminate epidermal wound closure remain obscure, as do National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $138,541 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $2,008,515 allocation. See details
National Institutes of Health 9/30/2009
BAYLOR COLLEGE OF MEDICINE $137,310 Trans-NIH Recovery Act Research Support Purpose: To test the hypothesis that coactivator posttranslational modifications control the in vivo systems biology of mammals. National Institutes of Health 9/30/2010
BAYLOR COLLEGE OF MEDICINE $136,816 Trans-NIH Recovery Act Research Support This award supports stipends of two graduate students while they pursue their graduate studies in Neuroscience. This application requests continuing support for Predoctoral Training in Systems and Integrative Biology with specific emphasis on Graduate Tr National Institutes of Health 8/03/2009
BAYLOR COLLEGE OF MEDICINE $136,000 Trans-NIH Recovery Act Research Support This application is a request for an administrative supplement from the American Recovery and Reinvestment Act of 2009 (announcement NOT-OD-09-056) for our parent grant, HD33438, G?Analysis of Reproductive Function Using Transgenic MiceG?. Our parent gra National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $134,038 Trans-NIH Recovery Act Research Support The initial and current funding periods of the Nuclear Receptor Signaling Atlas has demonstrated the ability of the Consortium members to pursue the collective goal of generation and validation of high-content datasets and the distribution of these data t
This spending item is part of a $220,057 allocation. See details
National Institutes of Health 3/11/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $133,968 Trans-NIH Recovery Act Research Support This is an administrative supplement, to a parent award which investigates the interaction between genetic variation and modifiable environments in the determination of incident coronary heart disease (CHD). The investigator's percent effort and salary s
This spending item is part of a $533,968 allocation. See details
National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $132,730 Trans-NIH Recovery Act Research Support The main purpose of this supplement were to save jobs and supplement unanticipated expansion. Abstract: The parent grant is focused on the role of the transcription factors ELF4 and KLF4 on the development and maintenance of CD8+ T cell memory. In this su National Institutes of Health 7/09/2010
BAYLOR COLLEGE OF MEDICINE $129,006 Trans-NIH Recovery Act Research Support Discover the switch permitting non-homologous recombination using expression analysis, proteome analysis, cell sorting and biofilm. ABSTRACT - In this extension of our previous Aim 2, Identification of new proteins and role(s) of the starvation/general s National Institutes of Health 9/18/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $128,805 Trans-NIH Recovery Act Research Support Tuberculosis has been declared a global emergency by the WHO and a priority for vaccine development by the NIH. The currently used BCG vaccine offers variable protection against children but not adults. Various sub unit and DNA vaccines and attenuated myc National Institutes of Health 9/27/2009
UNIVERSITY OF HOUSTON SYSTEM $127,599 Trans-NIH Recovery Act Research Support The overall goal of our research is to elucidate the role(s) of antimicrobial peptides such as defensins at the ocular surface. These peptides are likely to particpate in direct antimircrobial killing, regulation of immune responses and wound healing. T National Institutes of Health 9/01/2009
BAYLOR COLLEGE OF MEDICINE $127,421 Trans-NIH Recovery Act Research Support The purpose of this grant is to improve our ability to target drugs to particuliar protein conformations and thereby deliver highly specific drug action. Conformation changes and protein interactions underlie the function of many protiens, but are partic National Institutes of Health 4/22/2010
UNIVERSITY OF TEXAS M D ANDERSON $124,612 Trans-NIH Recovery Act Research Support CML (chronic myeloid leukemia) is unique in that the BCR/ABL oncogene drives disease onset and progression. Therapies inhibiting the BCR/ABL kinase, such as imatinib mesylate, have dramatically altered the treatment of chronic phase disease, but are less National Institutes of Health 9/30/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $120,594 Trans-NIH Recovery Act Research Support 'The purpose of this grant is to improve the prevention of cardiovascular disease by using recent genetic discoveries to identify who is at risk of developing a heart attack and by improved understanding of the genes that control the levels of fats (trigl
This spending item is part of a $996,476 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF HOUSTON SYSTEM $120,000 Trans-NIH Recovery Act Research Support The objective of this request for an administrative supplement to HD 2 P01 HD35946-10 (Spina Bifada: Cognitive and Neurobiological Variability) is to accelerate the rate at which the science of the project can be completed. Specifically, we wish to acce National Institutes of Health 9/16/2009
BAYLOR COLLEGE OF MEDICINE $117,900 Trans-NIH Recovery Act Research Support The purpose of the supplement is to maximize study retention and to amplify the effects of the lifestyle intervention and to retain staff positions. The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS M D ANDERSON $117,418 Trans-NIH Recovery Act Research Support The overall goal of this University of Texas M. D. Anderson Cancer Center Genitourinary SPORE in Bladder Cancer is to facilitate innovative translational research in the prevention, detection, and treatment of this disease leading to the elimination of bl National Institutes of Health 9/15/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $117,105 Trans-NIH Recovery Act Research Support The objective of this request for an administrative supplement to 2 P50 HD052117-03, Texas Center for Learning Disabilities, to take advantages of unique opportunities to accelerate the tempo of the science of this synergistic, multi-disciplinary research
This spending item is part of a $363,777 allocation. See details
National Institutes of Health 9/24/2009
BAYLOR COLLEGE OF MEDICINE $116,416 Trans-NIH Recovery Act Research Support The Ku heterodimer is a high affinity DNA end binding protein that mediates various roles at the telomere, including telomere end protection, telomere length regulation, and telomeric silencing. Specific Aim 1 of 5R01GM077509 is to G?further define struc National Institutes of Health 12/25/2009
UNIVERSITY OF TEXAS M D ANDERSON $115,500 Trans-NIH Recovery Act Research Support The Gcn5 histone acetyltransferase (HAT) is implicated in gene activation in organisms from yeast to humans. Although the structure of Gcn5 and the components of Gcn5-containing complexes (e.g. STAGA/TFTC) are well defined, the functions of Gcn5 in mammal National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $115,125 Trans-NIH Recovery Act Research Support The goal of this supplement is to initiate a new research direction for the PI in iPS field. The RFWD3 protein is originally identified as a putative ATM substrate in response to DNA damage. Subsequent biochemical analysis in our lab revealed that RFWD3 f National Institutes of Health 8/31/2009
BAYLOR COLLEGE OF MEDICINE $110,110 Trans-NIH Recovery Act Research Support Purchase of Biospectrum 600 Imaging System, Stepone Plus RT PCR System and Thermo Nanodrop Spectrophotometer National Institutes of Health 12/04/2009
BAYLOR COLLEGE OF MEDICINE $109,002 Trans-NIH Recovery Act Research Support The purpose of this study is to dissect the role of coactivators in cellular function. Steroid hormones stimulate growth, maturation and the development of new biochemical capacities in their endocrine target organs and are keys to understanding multiple National Institutes of Health 8/04/2010
BAYLOR COLLEGE OF MEDICINE $107,259 Trans-NIH Recovery Act Research Support Clinical Outcomes and Survival in Glioma Patients: The third aim of the parent grant will examine markers of clinical outcome and survival. As discussed below, this analysis is heavily dependent on having detailed treatment and follow-up data for each ca National Institutes of Health 9/17/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $104,898 Trans-NIH Recovery Act Research Support Multiple sclerosis (MS) is a chronic central nervous system disease that affects 2.5 million patients worldwide. Currently, there is no cure for MS, but a number of disease modifying drugs have been either approved by the FDA or undergoing clinical trials National Institutes of Health 8/11/2009
BAYLOR COLLEGE OF MEDICINE $104,733 Trans-NIH Recovery Act Research Support 'The purpose of this grant is to determine the effect of HAART on HPV infection and HPV-related anal dysplasia in HIV-infected individuals.Abstract: HIV-infected individuals have improved survival in the highly active antiretroviral therapy (HAART) era, b National Institutes of Health 9/15/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $103,147 Trans-NIH Recovery Act Research Support Preventing Depression in People with Epilepsy: An Extension of Project UPLIFT Funded by the Centers for Disease Control and Prevention (CDC) as a home-based treatment for depression in people with epilepsy, Project UPLIFT was developed to provide group d
This spending item is part of a $967,019 allocation. See details
National Institutes of Health 9/20/2009
BAYLOR COLLEGE OF MEDICINE $102,335 Trans-NIH Recovery Act Research Support The goal of this project is to understand the mechanism of cell trafficking and inflammatory responses in nonlymphoid tissues in the settings of autoimmune diseases. CXCL16 is the second member of the chemokine family with a transmembrane domain. The rece National Institutes of Health 9/13/2010
BAYLOR COLLEGE OF MEDICINE $101,829 Trans-NIH Recovery Act Research Support Develop technologies for assessment of aortic aneurysms prone to rupture or dissection. Thoracic and abdominal aortic aneurysms (TAA and AAA) are life threatening conditions that comprise the thirteenth leading cause of death in the United States. For bot
This spending item is part of a $829,915 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $101,218 Trans-NIH Recovery Act Research Support My career goal is to become an established researcher in the molecular epidemiology of cancer. This goal builds upon my previous education and training in medicine and epidemiology but requires further training in molecular techniques and genetic epidemio National Institutes of Health 9/15/2009
HOUSTON AREA COMMUNITY SERVICES, INC $101,000 ARRA Health Center Integrated Services Development Initiative[g1] IDS funds allow HACS to expand primary care and behavioral health access to residents in the approved service area in the City of Houston/Harris County. Project completed. Health Resources and Services Administration 3/27/2009
MOTHERLAND INC $101,000 ARRA Health Center Integrated Services Development Initiative[g1] ARRA-INCREASE SERVICES TO HEALTH CENTERS Health Resources and Services Administration 3/23/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $100,568 Trans-NIH Recovery Act Research Support Nonsyndromic cleft lip and palate (NSCLP) is a common birth defect affecting approximately 4,000 newborns each year in the US and a million worldwide. Multidisciplinary approaches have improved the care of these children but long-term problems persist and
This spending item is part of a $200,207 allocation. See details
National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $100,001 Trans-NIH Recovery Act Research Support Muscle wasting is a serious problem for patients with chronic kidney disease (CKD), occurring independently of dietary factors. Muscle protein losses are due to an increase in muscle protein degradation plus a smaller decrease in protein synthesis. We h National Institutes of Health 1/26/2010
BAYLOR COLLEGE OF MEDICINE $100,000 Trans-NIH Recovery Act Research Support The primary aim of the parent grant is to identify and characterize bladder cancer stem cells (CSCs), In this administrative supplement, we propose the procurement of a cutting edge technology (the Fluidigm System) that was developed in Stanford Universi National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $99,940 Trans-NIH Recovery Act Research Support The vascular endothelium functions both as a barrier and as a targeting site during development and metastasis of breast tumors. The hypothesis for studies in our application is that novel nanovectors to capture proteins associated with angiogenic blood v National Institutes of Health 9/01/2009
WILLIAM MARSH RICE UNIVERSITY $99,869 Trans-NIH Recovery Act Research Support MedMyst III will create web-based games to effectively engage middle school students in science and present current NIAID-funded research on infectious diseases. The excitement of doing science and the variety of science career opportunities will be key e National Institutes of Health 1/14/2010
BAYLOR COLLEGE OF MEDICINE $99,859 Trans-NIH Recovery Act Research Support SUMMARY PURPOSE: Involve middle school teachers in biomedical research that they can translate into lessons for their students. ABSTRACT: The Foundations for Student Success Project (PARENT GRANT) is creating a new curriculum for after school programs to National Institutes of Health 7/06/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $99,000 Trans-NIH Recovery Act Research Support Systemic Lupus Erythematosus (SLE) is a heterogeneous disorder characterized by autoimmunity and the development of progressive immune complex renal disease. The pathogenesis of SLE is complex and multi- factorial; substantial clinical and experimental da National Institutes of Health 9/04/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $98,866 Trans-NIH Recovery Act Research Support The long-term goal is to elucidate structure/function relationships in the microbial sensory rhodopsins, a family of visual pigment-like heptahelical photoreceptors, to elucidate principles of membrane receptor photoactivation and receptor interactions wi National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $97,590 Trans-NIH Recovery Act Research Support This supplement is for equipment to support the processing, storage, and analysis of samples collected for the parent grant, Depressive Symptoms and Genetic Influences on Cardiac Outcomes (1R01NR010235). The parent grant focuses on defining the subgroup o National Institutes of Health 5/13/2010
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $97,238 Trans-NIH Recovery Act Research Support My ultimate objective is to conduct effective, independent research in cancer prevention and control, focusing on behavioral science applications for underserved populations, beginning with studying Hispanic cancer survivors. Specifically, I wish to devel National Institutes of Health 9/21/2009
BAYLOR COLLEGE OF MEDICINE $96,118 Trans-NIH Recovery Act Research Support This administrative Support requests funding to replace old equipment needed for all projects of P01 AI 57788. This replacement equipment will enhance progress in research on human noroviruses by providing state of the art systems to quantitate virus loa National Institutes of Health 4/19/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $96,076 Trans-NIH Recovery Act Research Support The purpose of the funding is to increase enrollment in a clinical trial of erythropoietin in TBI patients (Projects 1 and 2), and to purchase equipment for Project 3. Projects 1 and 2 of our grant are a clinical trial of 200 severe TI patients. The goa
This spending item is part of a $120,000 allocation. See details
National Institutes of Health 9/07/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $95,267 Trans-NIH Recovery Act Research Support This award is a Recovery Act Administrative Supplement for the G?NIH Pathway to Indepedence Award SchemeG? (K99/R0O), 4R00A1072961-02. The overall scope of the project is the study of pathogenesis of Enterococcus faecium, one of the most difficult bacteri National Institutes of Health 8/02/2010
BAYLOR COLLEGE OF MEDICINE $93,900 Trans-NIH Recovery Act Research Support Supplementary request for acceleration of the project: As indicated above, we now need to characterize the specific transcription factors and molecular events by which ERK1/2 controls the expression of genes that impact both ovulation (including COC expan National Institutes of Health 8/11/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $91,218 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Austin /Travis County will prevent and reduce tobacco use by working with community partners in schools, worksites, health care settings, faith-based organizations, retail settings, and the media. Key activities include assisting ... Show more
This spending item is part of a $7,473,150 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
BAYLOR COLLEGE OF MEDICINE $89,864 Trans-NIH Recovery Act Research Support To date, one must conclude that the pace of progress in disease control and preservation of functional integrity and quality of life for pediatric brain tumors remains below that of most other major types of childhood cancers. Recent advances in cellular
This spending item is part of a $381,202 allocation. See details
National Institutes of Health 8/20/2009
BAYLOR COLLEGE OF MEDICINE $89,119 Trans-NIH Recovery Act Research Support Congenital diaphragmatic hernia (CDH), a life-threatening birth defect, is a major cause of pediatric mortality and mobility. The pathological anomalies are characterized by the inappropriate protrusion of the abdominal contents, possibly including the st National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $88,510 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): In animals, cells undergoing apoptosis and necrosis are rapidly internalized by other cells via phagocytosis (engulfment) and degraded inside phagocytes. The removal of these dying cells provides a safe means for elimi National Institutes of Health 2/12/2010
BAYLOR COLLEGE OF MEDICINE $86,404 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
BAYLOR COLLEGE OF MEDICINE $84,219 Trans-NIH Recovery Act Research Support Primary care practice-based research networks (PBRNs) often report high participation rates in their studies. The NIH recognizes PBRNs as important vehicles for translational research projects, strongly supporting them through Clinical and Translational S
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/25/2009
BAYLOR COLLEGE OF MEDICINE $82,900 Trans-NIH Recovery Act Research Support This project is focused on elucidating molecular mechanisns of skeletal abnormalities in tricho-rhino-phalangeal syndrome.Mutations of the human TRPS1 gene cause a dominantly inherited skeletal dysplasia tricho-rhino-phalangeal syndrome (TRPS). Although National Institutes of Health 1/28/2010
UNIVERSITY OF TEXAS M D ANDERSON $82,462 Trans-NIH Recovery Act Research Support Patient navigation (PN) is a community-centered approach that can potentially reduce health disparities by enhancing access to care at an earlier stage of the disease continuum for underserved populations, such as racial/ethnic minorities or individuals w
This spending item is part of a $337,850 allocation. See details
National Institutes of Health 8/10/2011
UNIVERSITY OF HOUSTON SYSTEM $82,167 Trans-NIH Recovery Act Research Support The cohort for this project is a group of 400 (111 of the original 118 at the UH site are still active and we expect to examiner 108 in year 11 of the study) ethnically diverse, myopic young adults currently 17-123 years of age with 11 years of standardiz National Institutes of Health 9/14/2009
BAYLOR COLLEGE OF MEDICINE $81,823 Trans-NIH Recovery Act Research Support Purpose: To test the hypothesis that coactivator posttranslational modifications control the in vivo systems biology of mammals.
This spending item is part of a $124,650 allocation. See details
National Institutes of Health 9/30/2010
BAYLOR COLLEGE OF MEDICINE $80,956 Trans-NIH Recovery Act Research Support OVERALL PURPOSE: TODAY is a collaborative group funded by the National Instituate of Diabetes and Digestive and Kidney Diseases (NIDDK) to conduct +B20t a clinical trial of therapies in children with type 2 diabetes (T2D). The TODAY study has enrolled 70
This spending item is part of a $1,102,576 allocation. See details
National Institutes of Health 4/12/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $77,941 Trans-NIH Recovery Act Research Support Cochlear implants are commonly used in young children to treat deafness. This electronic device receives incoming sounds and electrically stimulates the auditory nerve, thereby bypassing the malfunctioning inner ear. Achieving optimal results with a cochl
This spending item is part of a $420,446 allocation. See details
National Institutes of Health 8/01/2010
UNIVERSITY OF HOUSTON SYSTEM $77,698 Trans-NIH Recovery Act Research Support Stroke is the leading cause of serious long-term disability in the United States. Adults who have strokes in the right side of the brain often 'miss the point' of what they hear, read, or see -- a life-altering problem that can have devastating effects o
This spending item is part of a $754,665 allocation. See details
National Institutes of Health 9/02/2009
BAYLOR COLLEGE OF MEDICINE $74,628 The purpose of the contract is to provide services for the planning, implementation, and coordination of Multi-cohort Eating and Activity Study for Understanding Reporting Error (MEASURE). The scope of this project is establishing the MEASURE Coordinatin
This spending item is part of a $2,457,255 allocation. See details
National Institutes of Health 8/30/2010
ARCHIMAGE INC $74,519 Trans-NIH Recovery Act Research Support 'We are developing a casual game played on a cell phone to teach effective food parenting practices using simulated parent-child interaction sequences with feedback and goal setting.
This spending item is part of a $350,147 allocation. See details
National Institutes of Health 5/27/2009
BAYLOR COLLEGE OF MEDICINE $73,918 Trans-NIH Recovery Act Research Support As an observational study that also serves as a resource for ancillary treatment trials, the multicenter NASH Database study provides a unique opportunity to understand the causes of NASH, identify treatments, and facilitate diagnosis. This supplemen
This spending item is part of a $149,038 allocation. See details
National Institutes of Health 1/25/2010
UNIVERSITY OF TEXAS M D ANDERSON $73,785 Recovery Act Comparative Effectiveness Research - AHRQ Prostate cancer is the most common solid tumor and the second leading cause of cancer death among American men. While surgery, radiation and observation have all been deemed appropriate for newly diagnosed men, tremendous uncertainty remains rega... Show more
This spending item is part of a $7,572,695 allocation. See details
Agency for Healthcare Research and Quality 8/12/2010
UNIVERSITY OF HOUSTON SYSTEM $72,407 Trans-NIH Recovery Act Research Support Pathogenic bacteria must assemble and secrete virulence factors to interact with host tissues and cause disease. Gram-negative bacteria have an outer membrane in addition to a cytoplasmic membrane and must secrete virulence factors across both these barri National Institutes of Health 9/30/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $72,003 Trans-NIH Recovery Act Research Support Studies of quantitative image processing for longitudinal neuroimaging followup have been reported for more than two decades. Many algorithms and methods of brain image processing and analysis have been reported, validated and are freely available, but ve National Institutes of Health 9/17/2009
UNIVERSITY OF HOUSTON SYSTEM $71,923 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
WILLIAM MARSH RICE UNIVERSITY $69,383 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $2,008,515 allocation. See details
National Institutes of Health 9/30/2009
TEXAS CHILDREN'S HOSPITAL $68,500 Technical support and administrative/management services: Task Order 6, Antiviral and Immune Plasma Infrastructure Development
This spending item is part of a $12,962,657 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $67,060 Trans-NIH Recovery Act Research Support The purpose of this multi-site, randomized, controlled trial is to determine the optimal frequency of repositioning nursing facility residents with mobility limitations who are at moderate and high risk for pressureulcer development who are cared for on h National Institutes of Health 7/14/2009
BAYLOR COLLEGE OF MEDICINE $66,005 Trans-NIH Recovery Act Research Support The purpose of this grant is to provide summer research experience for a high school teacher under ARRA mechanism. Earlier, we have reported that mitotic regulation and apoptosis are mechanistically linked. Rad21, an integral component of cohesin, is cle National Institutes of Health 6/01/2009
BAYLOR COLLEGE OF MEDICINE $65,208 Recovery Act Comparative Effectiveness Research - AHRQ The Agency for Health Care Research and Quality (AHRQ), through its Effective Health Care Program (http://effectivehealthcare.ahrq. gov), supports the development of comparative effectiveness reviews (CERs), many of which have associated products... Show more
This spending item is part of a $1,497,995 allocation. See details
Agency for Healthcare Research and Quality 9/01/2010
UNIVERSITY OF HOUSTON SYSTEM $62,830 Trans-NIH Recovery Act Research Support Cochlear implants are commonly used in young children to treat deafness. This electronic device receives incoming sounds and electrically stimulates the auditory nerve, thereby bypassing the malfunctioning inner ear. Achieving optimal results with a cochl
This spending item is part of a $420,446 allocation. See details
National Institutes of Health 8/01/2010
BAYLOR COLLEGE OF MEDICINE $61,877 Trans-NIH Recovery Act Research Support Malignant glioma is the most common and lethal primary brain tumor. Despite the improvement of imaging technology and surgical removal of the tumors significantly reduces the mortality of malignant glioma, how to enhance the sensitivity to radiation and c National Institutes of Health 7/27/2011
BAYLOR COLLEGE OF MEDICINE $60,553 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $60,444 Trans-NIH Recovery Act Research Support PURPOSE:Elucidation of the mechanisms through which diet modulates physiology and aging will lead to interventions to reduce the frequency of aging-related diseases. ABSTRACT:Aging is a progressive decline in biological functioncharacterized by increased National Institutes of Health 5/19/2009
UNIVERSITY OF TEXAS M D ANDERSON $60,347 To establish a coordinated process structured to meet previously-identified scientific needs for quantitative imaging biomarkers. The long-term objective is to establish processes and profiles that will lead to acceptance by the imaging community, clinica
This spending item is part of a $2,412,566 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $59,996 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $59,392 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for 4 high school students in health-related scientific research. The goal of this program is to expose trainees at the earliest stage of their career to translational research in cell and gene therapy. Thi National Institutes of Health 5/29/2009
BAYLOR COLLEGE OF MEDICINE $59,392 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for 4 high school students in health-related scientific research. The goal of this program is to expose trainees at the earliest stage of their career to translational research in cell and gene therapy. Thi National Institutes of Health 6/05/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $58,493 Trans-NIH Recovery Act Research Support This award is a supplement to grant R01A1075091-03 is to support the doctoral training of Arely Gonzalez in the laboratory of the P1, Michael Lorenz, in the Program for Microbiology and Molecular Genetics at the University of Texas Graduate School for Bio National Institutes of Health 9/20/2010
UNIVERSITIES SPACE RESEARCH ASSOCIATION $56,574 Trans-NIH Recovery Act Research Support Motion sickness is a debilitating condition that affects a wide range of individuals in both daily life and in pathological conditions. While it is widely seen in many clinical settings, it remains difficult to objectively evaluate and treat. Recent work
This spending item is part of a $374,203 allocation. See details
National Institutes of Health 2/04/2010
BAYLOR COLLEGE OF MEDICINE $56,481 Trans-NIH Recovery Act Research Support This supplement is requesting funding from the American Recovery and Reinvestment Act of 2009 to accelerate the pace of its research. This grant is in its sixth year of funding and has been highly productive. In the first 5 years of funding, the progress National Institutes of Health 7/29/2010
BAYLOR COLLEGE OF MEDICINE $55,594 Trans-NIH Recovery Act Research Support The Prenatal Cytogenetic Diagnosis by Array-Based Copy Number Analysis (aCNA) administrative supplement has goals consistent with ARRA funding guidelines. The supplement will: 1) create new geographically dispersed jobs for the entire 2 year period, 2) a
This spending item is part of a $744,988 allocation. See details
National Institutes of Health 9/29/2009
RADIOMEDIX, INC. $55,434 Trans-NIH Recovery Act Research Support It has been suggested that the small fraction of tumor cells capable of initiating local or distant recurrence exhibit properties of stem cells, and that identification and molecular characterization of putative cancer stem cells will lead to better outco
This spending item is part of a $535,374 allocation. See details
National Institutes of Health 9/15/2009
BAYLOR COLLEGE OF MEDICINE $54,000 Trans-NIH Recovery Act Research Support Purpose: to enhance our understanding of human visual processing and perception. Abstract: The ability to identify and discriminate an endless array of visual objects is a challenge to even the most powerful computers, yet humans can rapidly make these d National Institutes of Health 8/17/2009
UNIVERSITY OF HOUSTON SYSTEM $53,954 Trans-NIH Recovery Act Research Support We have recently shown that Toll-like receptors (TLRs) are involved in regulation of gene expression of drug metabolizing enzymes1, 2. The overall goal of this project is to determine the role of these receptors in the regulation of drug metabolism and to National Institutes of Health 7/31/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $53,464 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE INC $52,949 Trans-NIH Recovery Act Research Support The goals of this supplement are to increase our productivity and reduce environmental waste. This application is a request for an administrative supplement from the American Recovery and Reinvestment Act of 2009 for our parent grant, CA60651, G?Mouse Mod National Institutes of Health 9/02/2009
BAYLOR COLLEGE OF MEDICINE $51,710 Trans-NIH Recovery Act Research Support How do amoebae detect and kill bacteria? Free-living amoebae prey upon diverse species of microbes in nature, including some that infect humans. The antagonistic dynamics of this processG??microbial resistance and amoeba counter-resistanceG??has led to National Institutes of Health 6/18/2009
UNIVERSITY OF TEXAS M D ANDERSON $50,001 Trans-NIH Recovery Act Research Support The University of Texas M. D. Anderson Cancer Center (MDACC) is a free-standing comprehensive cancer center within the University of Texas system. The mission of the MDACC is to eliminate cancer in Texas, the nation and the world through outstanding integ National Institutes of Health 9/23/2009
BAYLOR COLLEGE OF MEDICINE $50,000 Trans-NIH Recovery Act Research Support ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) which is intended to improve the efficiency and effectiveness of the clinical process and reduce clinical trial costs. The Dan L. Duncan Cancer Center (DLDCC) will provide National Institutes of Health 9/22/2009
UNIVERSITY OF TEXAS M D ANDERSON $50,000 Trans-NIH Recovery Act Research Support The primary cause of skin cancer is chronic exposure to ultraviolet (UV) rays from sunlight. A crucial event in the prevention of UV-induced skin cancer is the repair of DNA damage and / or the removal of the damaged cell through apoptotic mechanisms. Fai National Institutes of Health 9/21/2009
UNIVERSITY OF TEXAS M D ANDERSON $49,802 Trans-NIH Recovery Act Research Support In the United States alone, approximately 500,000 deaths will result from rupture of plaques considered 'insignificant' on an angiographic evaluation. Available screening and diagnostic methods are insufficient to identify possible victims before the even
This spending item is part of a $1,429,601 allocation. See details
National Institutes of Health 9/15/2009
BAYLOR COLLEGE OF MEDICINE $48,997 Trans-NIH Recovery Act Research Support Training of summer students for biomedical research. Protein biosynthetic quality control systems orchestrate the elimination of newly synthesized proteins that fail to achieve their correct native structure. Our goal is to elucidate how these systems ar National Institutes of Health 7/16/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $48,963 Trans-NIH Recovery Act Research Support The objective of this career development award is to provide Dr. Sharon Giordano with the experience and knowledge necessary to become an independent health services researcher in the field of breast cancer. Dr. Giordano, who is a medical oncologist and M National Institutes of Health 9/15/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $48,365 Trans-NIH Recovery Act Research Support Genome-wide association (GWA) studies have made great progress in the identification of regions that are likely to contain genetic variants contributing to the risk of cardiovascular, lung and blood diseases. Despite these successes, variants identified t
This spending item is part of a $2,343,137 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF TEXAS M D ANDERSON $48,141 The MD Anderson Cancer Center has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial cases. These cases are all primary and untreated. Th National Institutes of Health 9/21/2010
BAYLOR COLLEGE OF MEDICINE $48,114 Trans-NIH Recovery Act Research Support GLP-2 is an intestinotrophic growth factor that stimulates mucosal growth by increasing crypt cell proliferation and decreasing enterocyte cell apoptosis. GLP-2 also stimulates intestinal blood flow, improves nutrient absorption, and inhibits gut motility National Institutes of Health 9/07/2009
BAYLOR COLLEGE OF MEDICINE $48,046 Trans-NIH Recovery Act Research Support The purpose of this study is to understand retinoid-dependent cardiovascular development and analyze ventricular proliferation in Raldh2 mutants. National Institutes of Health 7/16/2009
COMMUNITY DEVELOPMENT INSTITUTE HEAD START $47,884 ARRA - Head Start ARRA funds for Early Head Start Quality Improvement and Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06. Administration for Children and Families 7/10/2009
BAYLOR COLLEGE OF MEDICINE $47,256 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
WILLIAM MARSH RICE UNIVERSITY $46,118 Trans-NIH Recovery Act Research Support Biological systems universally employ cascades of binding/catalytic events to transmit information regarding environmental and physiological states. This communication network requires that protein function be altered by allosteric mechanisms. The dearth National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $45,999 Trans-NIH Recovery Act Research Support This supplemental award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ANBL0931, which is a Phase III Study of Chimeric Antibody 14.18 in High-Risk Neuroblastoma. The primary objective of study ANBL09
This spending item is part of a $1,981,588 allocation. See details
National Institutes of Health 8/07/2009
GALENA PARK INDEPENDENT SCHOOL DISTRICT $45,242 ARRA - Head Start ARRA Cost of Living (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act - The Galena Park ISD (GPISD) Early Head Start program is seeking to continue the provision of child development services Administration for Children and Families 7/01/2009
BAYLOR COLLEGE OF MEDICINE $45,117 Trans-NIH Recovery Act Research Support This application is a request for an administrative supplement for our parent grant, U01 HD060496, G?Identification of Small Molecule Contraceptives that Target the Male GermlineG? from the Eunice Kennedy Shriver National Institutes of Child Health and Hu National Institutes of Health 9/28/2009
BAYLOR COLLEGE OF MEDICINE $44,573 Trans-NIH Recovery Act Research Support Obesity prevalence in the US and other developed countries has increased dramatically in recent decades. This trend is affecting individuals at every age, including women of child- bearing age. A major concern is that maternal obesity during pregnancy may National Institutes of Health 12/18/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $44,415 Trans-NIH Recovery Act Research Support Heat shock proteins (Hsps) play dual roles in cellular biology; they are the first line of defense against cytotoxic stresses, and are tightly integrated into signaling and regulatory pathways under normal growth conditions. A subset of Hsps, including Hs National Institutes of Health 7/14/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $43,232 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $43,031 Trans-NIH Recovery Act Research Support Ectodomain shedding, the proteolytic cleavage of an integral membrane protein to release the extracellular domain from the host cell, affects a variety of biologically important proteins including growth factor precursors, cytokine receptors, amyloid prec National Institutes of Health 7/15/2009
BAYLOR COLLEGE OF MEDICINE $42,813 Trans-NIH Recovery Act Research Support The long-term objectives of this request for supplemental funding are to define the genetic, epigenetic, nutritional, and environmental factors that impact mammary gland development and function. With this supplemental grant we will use mRNA isolated from National Institutes of Health 9/24/2009
BAYLOR COLLEGE OF MEDICINE $42,104 Trans-NIH Recovery Act Research Support Our long term objectives are to understand the biochemical mechanisms that cause the feedback inhibition of hormonal or drug stimulation of the 22-adrenergic receptor (22AR) that mediates several important components of the 'fight-or-flight' response thro
This spending item is part of a $835,037 allocation. See details
National Institutes of Health 9/22/2009
WILLIAM MARSH RICE UNIVERSITY $41,684 Trans-NIH Recovery Act Research Support The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl
This spending item is part of a $1,878,342 allocation. See details
National Institutes of Health 5/02/2011
BAYLOR COLLEGE OF MEDICINE $41,534 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $41,436 Trans-NIH Recovery Act Research Support In Program Announcement PA-06-183: 'HEALTH DISPARITIES IN NIDDK DISEASES,' The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) seeks research to understand and mitigate issues of health disparities in high priority diseases within National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS M D ANDERSON $41,042 Trans-NIH Recovery Act Research Support This is funding building on a recently completed longitudinal study of smoking patterns in a popluation-based sample of Mexican origin adolescents (the MATCH study). This funding will further explore the genetic/non-genetic underpinnings of smoking and e
This spending item is part of a $47,925 allocation. See details
National Institutes of Health 3/31/2011
UNIVERSITY OF TEXAS M D ANDERSON $39,200 Trans-NIH Recovery Act Research Support In this proposal we will characterize a member of the family of phorbol ester receptors, protein kinase C epsilon (PKC), and its involvement in prostate carcinogenesis. In the previous funding period we have established that phorbol esters, natural compou
This spending item is part of a $631,497 allocation. See details
National Institutes of Health 7/16/2009
BAYLOR COLLEGE OF MEDICINE $38,942 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,747 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,747 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,747 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,747 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,747 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $38,569 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
WYLE LABORATORIES, INC. $38,265 Trans-NIH Recovery Act Research Support Motion sickness is a debilitating condition that affects a wide range of individuals in both daily life and in pathological conditions. While it is widely seen in many clinical settings, it remains difficult to objectively evaluate and treat. Recent work
This spending item is part of a $374,203 allocation. See details
National Institutes of Health 2/04/2010
BAYLOR COLLEGE OF MEDICINE $37,738 Trans-NIH Recovery Act Research Support This proposal is the first step in a major paradigm shift leading to global acceptance of evidence-based protocol-driven care as the optimal approach to treatment of pediatric rheumatic diseases by families, patients, and health care providers. Through th
This spending item is part of a $6,824,989 allocation. See details
National Institutes of Health 9/30/2009
PLX PHARMA INC $37,500 Trans-NIH Recovery Act Research Support PLx Pharma is a pharmaceutical company developing GI safer formulations of proven non-steroidal anti-inflammatory drugs (NSAIDs) including ibuprofen, aspirin and naproxen for prescription and over-the-counter markets. PLx has created novel NSAID formulati National Institutes of Health 1/26/2010
BAYLOR COLLEGE OF MEDICINE $36,858 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $36,858 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
BAYLOR COLLEGE OF MEDICINE $36,858 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
HOUSTON COMMUNITY COLLEGE, INC. $35,686 ARRA - Scholarships for Disadvantaged Students In order to address the nation's need for a pool of qualified registered nurses with ethnically diverse heritages, Houston Community College's Coleman College for Health Sciences will use the HRSA Scholarship for Disadvantaged Nursing Students program to... Show more Health Resources and Services Administration 6/14/2010
BAYLOR COLLEGE OF MEDICINE $35,510 Trans-NIH Recovery Act Research Support The interplay between chromatin structure and transcriptional regulators has an important role in gene regulation throughout development and differentiation. Because the mammary gland develops mostly postnatally and the hormones of puberty and pregnancy t National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $35,309 Trans-NIH Recovery Act Research Support Squire's Quest! was a proven-effective video game that increased children's FJV consumption by 1.0 servings a day; however, total consumption was still below recommended levels, indicating that additional work was needed. Additionally, results revealed th National Institutes of Health 9/29/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $35,160 Trans-NIH Recovery Act Research Support Multiple sclerosis (MS) is a chronic central nervous system disease that affects 2.5 million patients worldwide. Currently, there is no cure for MS, but a number of disease modifying drugs have been either approved by the FDA or undergoing clinical trials National Institutes of Health 5/29/2009
BAYLOR COLLEGE OF MEDICINE $35,000 Trans-NIH Recovery Act Research Support PURPOSE: Equipment Acqusition. A Beckman-Coulter IC-100 High Throughput automated microscope will be acquired from the University of Texas, Southwestern, and moved to Houston for use in the Integrated Microscopy Core and as a resource for our NICHD U National Institutes of Health 9/22/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $35,000 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) and its metabolic derangements substantially affect the well-being of children. In order to define the nature, magnitude, and temporal evolution of the adverse effects of progressive CKD, we propose to extend the follow-up of
This spending item is part of a $329,400 allocation. See details
National Institutes of Health 6/11/2010
UNIVERSITY OF TEXAS M D ANDERSON $34,560 Trans-NIH Recovery Act Research Support This proposed STEER program is intended to support the annual participation of eight academically talented undergraduates in the Environmental Health Sciences Summer Undergraduate Research Program (EHS-SURP). The overall goal of EHS-SURP is to provide an National Institutes of Health 6/17/2009
BAYLOR COLLEGE OF MEDICINE $34,527 Trans-NIH Recovery Act Research Support The vast majority of HIV-1 infections occur at mucosal surfaces in the body. There is therefore an immediate need for potent HIV vaccines that can provide barrier protection at mucosal surfaces. While there is this need,most HIV vaccines have been develop
This spending item is part of a $720,202 allocation. See details
National Institutes of Health 9/11/2009
BAYLOR COLLEGE OF MEDICINE $34,256 Trans-NIH Recovery Act Research Support The purpose was to stimulate progress on the paretnt grant and create/retain reserch positions for undergraduate students. The objective of the parent application is to determine the essential pathways that drive T cell independent B cell activation and I National Institutes of Health 6/04/2009
UNIVERSITY OF TEXAS M D ANDERSON $33,000 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $396,000 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $33,000 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $396,000 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $33,000 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $396,000 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF TEXAS M D ANDERSON $33,000 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $396,000 allocation. See details
National Institutes of Health 9/24/2009
BAYLOR COLLEGE OF MEDICINE $32,793 Trans-NIH Recovery Act Research Support This supplement is requesting funding from the American Recovery and Reinvestment Act of 2009 to accelerate the pace of its research. This grant is in its second year of funding and has been highly productive. During the first year of research funded by R National Institutes of Health 7/29/2010
TEXAS CHILDREN'S HOSPITAL $32,497 Trans-NIH Recovery Act Research Support This award provides funding for establishment of a consortium with the University of Illinois-Chicago, Texas Children's Hospital, & Baylor College of Medicine to obtain samples necessary to complete Phase II validation of novel biomarker profiles in the b
This spending item is part of a $92,740 allocation. See details
National Institutes of Health 9/25/2009
BAYLOR COLLEGE OF MEDICINE $30,492 Trans-NIH Recovery Act Research Support The objective of the proposed work is to understand how the Dmrt1 gene controls development and function of the testis. The testis has two essential functions: production of sperm, the cells that serve as vehicles for the immortality of male germ line DNA
This spending item is part of a $190,464 allocation. See details
National Institutes of Health 8/03/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $30,364 Trans-NIH Recovery Act Research Support For almost two decades, the W. M. Keck Center, which spans six biomedical institutions in the Greater Houston, Texas area, has trained pre- and postdoctoral fellows in biomedical informatics. Here we seek the renewal of one of our training programs (the N
This spending item is part of a $1,033,304 allocation. See details
National Institutes of Health 7/21/2009
New Integrated Beginnings, Inc $30,000 ARRA Strengthening Communities Fund The objectives of the Strengthening Communities Fund (SCF) are to (1) fund entities to provide training, technical assistance, and financial assistance to local faith-based and community organizations enabling them to more fully participate in economic re
This spending item is part of a $764,780 allocation. See details
Administration for Children and Families 9/23/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $29,900 Trans-NIH Recovery Act Research Support This is a continuation of a project, for which the long-term goal is to define T cell effector mechanisms at the level of the small intestinal epithelium, by characterizing the stimulatory and costimulatory signals that drive intestinal intraepithelial ly National Institutes of Health 8/12/2009
UNIVERSITY OF TEXAS M D ANDERSON $29,688 Trans-NIH Recovery Act Research Support My long-term goal is to become an established independent bio-behavioral epidemiologist and to design, implement and analyze studies that combine genetic and non-genetic influences on behaviors that effect cancer and other health outcomes. My proposal bui National Institutes of Health 9/15/2009
HOUSTON COMMUNITY COLLEGE, INC. $29,576 ARRA - Scholarships for Disadvantaged Students The Scholarships for Disadvantaged Students program provides scholarships to financially needy students enrolled in the Nursing Program. Health Resources and Services Administration 9/03/2009
BAYLOR COLLEGE OF MEDICINE $28,796 Trans-NIH Recovery Act Research Support Epileptic seizures during the first weeks of human life are very common and are associated with severe Morbidity and Mortality. Research conducted under the parent grant for this proposed administrative supplement is aimed at the development of new treatm National Institutes of Health 4/29/2011
UNIVERSITY OF TEXAS M D ANDERSON $28,324 Trans-NIH Recovery Act Research Support Purpose: The study will determine the influence of genetic risk factors on radiotherapy sensitivity among childhood cancer survivors, using the existing Childhood Cancer Survivor Study (CCSS) cohort. The Childhood Cancer Survivor Study (CCSS) is a retros
This spending item is part of a $410,944 allocation. See details
National Institutes of Health 7/16/2009
WILLIAM MARSH RICE UNIVERSITY $28,137 Trans-NIH Recovery Act Research Support The major goals of this project are to establish a method for optical analysis of neural circuits. Neuroplasticity is central to fundamental processes in the brain, including learning, recovery after brain injury, and neural circuit changes resulting from
This spending item is part of a $1,220,072 allocation. See details
National Institutes of Health 8/14/2009
HARRIS COUNTY HOSPITAL DISTRICT $27,900 ARRA - Prevention and Wellness--State Territories and Pacific Islands Grant funds to carry out statewide evidence-based initiatives that support obesity prevention and nutrition strategies. Initiative includes promotion of optimal nutrition and obesity prevention by facilitiating the development and... Show more
This spending item is part of a $2,797,900 allocation. See details
Centers for Disease Control and Prevention 2/06/2010
BAYLOR COLLEGE OF MEDICINE $27,446 Trans-NIH Recovery Act Research Support Cochlear outer hair cells enhance the sensitivity of mammalian hearing through active mechanical feedback powered by the membrane protein prestin. The long-term goal of our research efforts is to understand the mechanism by which prestin interacts with th
This spending item is part of a $296,552 allocation. See details
National Institutes of Health 7/15/2009
BAYLOR COLLEGE OF MEDICINE INC $26,806 Trans-NIH Recovery Act Research Support The purpose of this supplement was to support 3 summer students who were interested in careers in research. This was the first experience for 2 of these individuals and 1 was continuing his honors thesis in the lab. Cancer is a major cause of morbidity a National Institutes of Health 6/02/2009
BAYLOR COLLEGE OF MEDICINE $26,000 Trans-NIH Recovery Act Research Support This is an application for supplemental funding to accelerate the pace of the research project described in R21 DK082827-01, entitled ?Pathogenesis of Ketosis-Prone Diabetes?, to purchase an Indirect Calorimeter to pursue the research objectives proposed National Institutes of Health 12/30/2009
BAYLOR COLLEGE OF MEDICINE $25,371 Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C
This spending item is part of a $750,000 allocation. See details
National Institutes of Health 8/13/2009
UNIVERSITY OF TEXAS M D ANDERSON $25,007 Trans-NIH Recovery Act Research Support This supplemental award provides support to Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Supplements including: 1) High Risk Acute Lymphoblastic Leukemia (HR-ALL) - Our results establish that we can use comprehensive genom
This spending item is part of a $4,023,579 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF HOUSTON SYSTEM $24,969 Trans-NIH Recovery Act Research Support The goal of this project is to structurally understand how the thromboxane A2 synthase (TXAS), coordinates (couples) with the upstream cyclooxygenase (COX) isoform-1 (COX-1) vs. isoform-2 (COX-2) in the biosynthesis of TXA2 (a key pro-thrombotic mediator National Institutes of Health 6/01/2009
UNIVERSITY OF HOUSTON SYSTEM $23,907 Trans-NIH Recovery Act Research Support The purpose of the funding is to increase enrollment in a clinical trial of erythropoietin in TBI patients (Projects 1 and 2), and to purchase equipment for Project 3. Projects 1 and 2 of our grant are a clinical trial of 200 severe TI patients. The goa
This spending item is part of a $120,000 allocation. See details
National Institutes of Health 9/07/2009
BAYLOR COLLEGE OF MEDICINE $22,465 Trans-NIH Recovery Act Research Support This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/
This spending item is part of a $1,405,307 allocation. See details
National Institutes of Health 8/12/2009
BAYLOR COLLEGE OF MEDICINE $22,450 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
SIEMENS BUILDING TECHNOLOGIES INC $20,677 UNIV OF TEXAS HEALTH SCIENCE CTR AT HOUSTON - SP UT Professional Building BAU Upgrades Immediate Office of the Secretary of Health and Human Services 7/09/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $20,020 Trans-NIH Recovery Act Research Support Lung cancer is the leading cause of death in the United States. About 213,380 new cases of lung cancer will be diagnosed in 2008 accounting for over 160,390 deaths annually. Despite recent advances in treatment strategies, the overall 5-year survival rate National Institutes of Health 6/16/2009
WILLIAM MARSH RICE UNIVERSITY $20,000 Trans-NIH Recovery Act Research Support 'The overall goal of the DERC is to promote diabetes research in clinical metabolism and nutrition. Scope of the Overall Project: This Diabetes Endocrinology Research Center (DERC) application was submitted under a P30 grant mechanism in response to a RF
This spending item is part of a $675,500 allocation. See details
National Institutes of Health 9/21/2009
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $18,240 Trans-NIH Recovery Act Research Support The goal of this summer program is to offer an intensive laboratory experience for an undergraduate student, and to speed up our research progress in developing nanomedicine. Ms. Catherine Chen, a sophomore major in chemistry from Rice University has work National Institutes of Health 5/29/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $18,086 Trans-NIH Recovery Act Research Support Critical issues for improving the treatment of alcoholism are what neurobiological changes are responsible for the transition from non-dependent alcohol use to alcoholism, and what persistent changes mediate relapse. The goals of the present proposal are National Institutes of Health 7/15/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $17,864 Trans-NIH Recovery Act Research Support Facioscapulohumeral muscular dystrophy (FSHD) is a progressively debilitating syndrome that is the nation's third most common type of dystrophy, yet the development of directed therapies remains hampered by our poor understanding of its molecular basis. R National Institutes of Health 7/19/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $17,073 Trans-NIH Recovery Act Research Support Few studies have examined the relationship with gene on the DNA repair and apoptosis pathways. Our preliminary data support associations with several single nucleotide polymorphism in genes in these pathways but a larger sample size is needed to confirm t
This spending item is part of a $1,563,767 allocation. See details
National Institutes of Health 8/04/2009
BAYLOR COLLEGE OF MEDICINE $15,690 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE $15,400 Trans-NIH Recovery Act Research Support The objective of this study is to elucidate the mechanism by which testosterone inhibits spermatogonial differentiation after toxicant exposure of rats. Radiation will be used as a model toxicant in most studies and the relevance to chemical toxicants wil National Institutes of Health 7/11/2009
BAYLOR COLLEGE OF MEDICINE INC $13,508 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for Mr, SiyuanShen, an undergraduate student at the University of Washington in Seattle, in health-related scientific research.The student applied dimensional reduction techniques to simplify a highly compl National Institutes of Health 5/29/2009
WORLD WIDE TECHNOLOGY, INC $12,982 Cisco Hardware and Support Program Support Center 9/24/2009
BAYLOR COLLEGE OF MEDICINE $12,500 Trans-NIH Recovery Act Research Support This project will take advantage of the existing infrastructure of the PHACS Study which began protocol development in 2005 after successfully competing for funding by the NICHD. This is a multicenter, multidisciplinary and collaborative study. The PHACS
This spending item is part of a $1,012,474 allocation. See details
National Institutes of Health 9/29/2009
BAYLOR COLLEGE OF MEDICINE $12,341 Trans-NIH Recovery Act Research Support The purpose of this project is to define the molecular mechanisms of Cytochrome P4501A1 expression by polyclcyclic aromatic hydrocarbons (PAHs), in relation to carcinogenesis. Polycyclic aromatic hydrocarbons (PAHs) are present in cigarette smoke, particu National Institutes of Health 5/21/2010
BAYLOR COLLEGE OF MEDICINE $12,232 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Type 1 diabetes mellitus (T1DM) is currently managed using modulation of dietary carbohydrates and insulin. Paradoxical post-meal hyperglucagonemia is associated with post-prandial hyperglycemia in T1DM. Glucagon suppr National Institutes of Health 2/26/2010
DIGITAL RECONNAISSANCE, INC $8,235 F-Response Enterprise Edition plus 1 year of Maintenance Program Support Center 6/21/2010
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $7,223 Trans-NIH Recovery Act Research Support Vascular diseases can cause premature deaths. These deaths can be prevented by knowing who is at risk for the disease. The studies proposed are to identify the genes that predispose individuals to a number of vascular diseases. PUBLIC HEALTH RELEVANCE: Th National Institutes of Health 6/04/2009
FISHER SCIENTIFIC COMPANY L.L.C. $6,508 Clinitek Advantus urine Chemistry Analyzer Indian Health Service 9/26/2008
BAYLOR COLLEGE OF MEDICINE $1,799 Trans-NIH Recovery Act Research Support We will study decision-making processes in physicians under controlled experimental conditions, paired with the neuroimaging data. Litt National Institutes of Health 9/21/2010
BAYLOR COLLEGE OF MEDICINE $1,464 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
FISHER SCIENTIFIC COMPANY L.L.C. $248 Gaspack EZ Anaerobe Pouch Health Resources and Services Administration 2/25/2010
FISHER SCIENTIFIC COMPANY L.L.C. $143 Kimwipe SML 4 1/2 x 8 1/2 pack Fund Acct Number 250-11875000000 New England Medical Ctr Centers for Disease Control and Prevention 10/02/2009
FISHER SCIENTIFIC COMPANY L.L.C. $138 Syringe BD 60ML Luer-Lok and 50101128 Cell Scraper 25CM STR Fund Acct 250-10372-11875000000 New England Medical Ctr Centers for Disease Control and Prevention 12/04/2009
FISHER SCIENTIFIC COMPANY L.L.C. $120 Hemacytometer Counting Chamber Agency for Healthcare Research and Quality 6/17/2009
FISHER SCIENTIFIC COMPANY L.L.C. $83 Gaspack EZ Anarobe Pouch 20/PK Fund Acct ARRA R01 Vaccine Acct nbr 250-10372-11875000000 New England Medical Center Centers for Disease Control and Prevention 11/05/2009
FISHER SCIENTIFIC COMPANY L.L.C. $32 Water (RNA Grade) 1 Liter Fund acct number 250-11875000000 New England Medical Ctr Centers for Disease Control and Prevention 9/30/2009
BAYLOR COLLEGE OF MEDICINE $17 Trans-NIH Recovery Act Research Support The purpose of the funding is to increase enrollment in a clinical trial of erythropoietin in TBI patients (Projects 1 and 2), and to purchase equipment for Project 3. Projects 1 and 2 of our grant are a clinical trial of 200 severe TI patients. The goa
This spending item is part of a $120,000 allocation. See details
National Institutes of Health 9/07/2009
FISHER SCIENTIFIC COMPANY L.L.C. $16 Syringe/Needle TB 1CC 25Gauge x 5/8 inch 100/pk Agency for Healthcare Research and Quality 8/17/2009
FISHER SCIENTIFIC COMPANY L.L.C. $3 Kimwipes small 4.5 x 8.5 inch 280/pk Agency for Healthcare Research and Quality 7/20/2009
UNIVERSITY OF TEXAS M D ANDERSON $0 Trans-NIH Recovery Act Research Support Using high resolution comparative genomic hybridization (CGH) array analysis of 235 ovarian cancers, we have narrowed the most frequent region of copy number increase in ovarian cancers to an ~3.2 MB wide region at 3q26.2. Real time PCR of genes within th
This spending item is part of a $677,167 allocation. See details
National Institutes of Health 8/10/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $0 Trans-NIH Recovery Act Research Support The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include
This spending item is part of a $288,300 allocation. See details
National Institutes of Health 9/22/2009
BAYLOR COLLEGE OF MEDICINE $0 Trans-NIH Recovery Act Research Support scientific purpose of this project supplement is to accelerate the pace of discovery of the underlying mechanisms for intracellular calcium?s triggering of plasticity of synaptic connections between nerve cells within the visual cortex. The economic purp National Institutes of Health 1/29/2010
BAYLOR COLLEGE OF MEDICINE $0 National Center for Research Resources, Recovery Act Construction Support DESCRIPTION (provided by applicant): The objective of this proposal is to build out 3 floors (total) in the Jan and Dan Duncan Neurological Research Institute (NRI) to accelerate research in understanding and treating disorders... Show more
This spending item is part of a $14,895,273 allocation. See details
National Institutes of Health 3/25/2010
BAYLOR COLLEGE OF MEDICINE $0 Trans-NIH Recovery Act Research Support Type 1 diabetes is currently managed with diet and insulin therapy. The protocols planned in this trial will target post-prandial hyperglycemia using glucagon suppressors pramlintide and exenatide. This trial will aim to determine a safe and effective dos National Institutes of Health 6/15/2010
WILLIAM MARSH RICE UNIVERSITY $0 Trans-NIH Recovery Act Research Support Individual cells display stochastic variability in their responses to activating stimuli. In cells taking part in the innate immune response this variability seems very important. Cells react differently to the same stimulus, e.g. some proliferate some mo
This spending item is part of a $191,432 allocation. See details
National Institutes of Health 4/09/2010