Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Jefferson County, Ala., funds by Health and Human Services, Department of

Listing $117,484,360.45 in stimulus funds from Health and Human Services, Department of for Jefferson

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
UNITED WAY OF CENTRAL ALABAMA, INC. $6,322,686 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Jefferson County Department of Health, Alabama $13.3 Million (Obesity $6.3 Million, Tobacco $7 Million) Jefferson County's tobacco use prevention and cessation initiative will promote changes in policies to reduce smoking oppor... Show more
This spending item is part of a $6,972,663 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNITED WAY OF CENTRAL ALABAMA, INC. $5,807,234 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Jefferson County Department of Health, Alabama $13.3 Million (Obesity $6.3 Million, Tobacco $7 Million) Alabama ranks as the third unhealthiest state and the second most obese state in the nation. The Jefferson County project is... Show more
This spending item is part of a $6,285,057 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $3,860,410 Trans-NIH Recovery Act Research Support This study integrates three research programs and unique sources of female genital specimens to investigate the mucosal and systemic immune processes that impact the acquisition and progression of HIV-1 infection in women.
This spending item is part of a $3,982,810 allocation. See details
National Institutes of Health 9/25/2009
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY $3,249,114 ARRA - Early Head Start Award Title: JCCEO ARRA Early Head Start Expansion Award Description and Purpose: The JCCEO ARRA Early Head Start (EHS) Expansion Award provided funding to serve an additional 100 eligible children and families in Jefferson County, Alabama. This expansio Administration for Children and Families 11/23/2009
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY $2,487,742 ARRA - Community Services Block Grant The Community Services Block Grant American Recovery and Reinvestment Act of 2009 (Recovery Act) funds will be used to provide services to low-income individuals and families to assist in removing obstacles and solving problems that impede the achievement
This spending item is part of a $18,335,466 allocation. See details
Administration for Children and Families 4/10/2009
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY $2,244,868 ARRA - Head Start Award Title: JCCEO ARRA Head Start Expansion Award Description and Purpose: The JCCEO ARRA Head Start Expansion Award provided funding to serve an additional 120 eligible children and families In Jefferson County, Alabama in a newly established Head Start Administration for Children and Families 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $2,111,642 Recovery Act Comparative Effectiveness Research - AHRQ We propose a UAB K12 program in Comparative Effectiveness Research (CER) to support 4 CER Scholars. This K12 training will be facilitated by the UAB AHRQ-funded Center for Education and Research on Therapeutics (CERTs), AHRQ-funded T32 in Health ... Show more Agency for Healthcare Research and Quality 7/01/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $2,026,322 Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) is the most common type of inflammatory arthritis; while there are now many effective medications to treat it, these drugs vary greatly in cost (up to $15,000/year) and side effects and there is no way to predict which drug is be
This spending item is part of a $3,344,252 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,820,000 ARRA - Health Information Technology Professionals in Health Care This project will develop instructional materials on four key topics areas designed to provide skills to an expanded workforce for HIT implementation. We will develop course materials on the following topics: Terminology in Health Care... Show more Health and Human Services, Department of 4/02/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,748,851 Trans-NIH Recovery Act Research Support This research will start to identify and break down racial and ethnic communications barriers and will serve as a model that could be implemented at other cancer centers and hospitals nationwide to improve minority participation in clinical trials. While
This spending item is part of a $4,180,489 allocation. See details
National Institutes of Health 9/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,497,848 Recovery Act Comparative Effectiveness Research - AHRQ Comparative effectiveness research results, such as AHRQ's Comparative Effectiveness Reviews (CER), should reach all Americans, even hard-to-reach vulnerable groups. We propose a study in the Alabama Black Belt, which includes mostly African Amer... Show more Agency for Healthcare Research and Quality 9/28/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,484,852 Trans-NIH Recovery Act Research Support The increasing value of medical imaging has resulted in an exponential rise in its use for patient care. Unfortunately, there has been no effective concomitant rise of means to share and communicate these data, resulting in inadequate patient service, co
This spending item is part of a $1,612,462 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,434,100 ARRA - Systolic Blood Pressure Intervention Trial (SPRINT) - Senior
This spending item is part of a $2,708,560 allocation. See details
National Institutes of Health 9/24/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,375,775 Trans-NIH Recovery Act Research Support Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome affecting 5-10% of women of reproductive age. It is characterized by elevated circulating insulin, reduced insulin sensitivity, infertility, hyperandrogenism, and a multitude of symptoms that r National Institutes of Health 9/22/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,368,146 Trans-NIH Recovery Act Research Support The goal of this Administrative Supplement to the UAB Comprehensive Cancer Center Core Support Grant (2P30 CA 13148-38) is to provide funding for the recruitment of a clinical investigator who is early in his/her career and evinces a strong commitment to National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,337,427 Trans-NIH Recovery Act Research Support End stage renal disease (ESRD), one of the most serious and costly complications of systemic lupus erythematosus (SLE), occurs in a sub-set of patients with SLE-related renal involvement. Factors predisposing to ESRD presumably include both genetics and
This spending item is part of a $3,350,000 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,334,969 Trans-NIH Recovery Act Research Support Specific aims: 1) Establish a diverse coalition of policy makers, community members, and representatives and stakeholders from multiple systems and sectorseconomic development, business, education, labor, housing, transportation, environment, agriculture, National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,330,840 Trans-NIH Recovery Act Research Support This application is from the School of Dentistry (SOD) at the University of Alabama at Birmingham (UAB) in response to the NIDCR RFA-OD-09-005 titled Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources throug National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,303,696 Trans-NIH Recovery Act Research Support The UAB Comprehensive Cancer Center is the hub for cancer research activities at UAB and requests funding from the NCI through this mechanism to facilitate recruitment of two early stage investigators as part of the Center's membership. In particular we a National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,302,250 Trans-NIH Recovery Act Research Support Over the past two decades the importance of glial cells in normal brain development has become increasingly appreciated. In addition to their well recognized role in normal brain function, dysfunction of glial cells are now recognized to be of critical im National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,197,834 Trans-NIH Recovery Act Research Support The majority of diseases potentially amenable to gene-based therapeutic approaches will likely require systemic vector administration, especially those with vascular involvement such as metastatic cancer, pulmonary arterial hypertension (PAH) and various National Institutes of Health 5/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,139,067 The objective of this project is to study fetal growth patterns in pregnant women of various race/ethnic backgrounds in a longitudinal study and to examine factors that affect healthy pregnancy, fetal growth and perinatal outcomes. The primary goals of t
This spending item is part of a $2,414,063 allocation. See details
National Institutes of Health 9/24/2010
JEFFERSON COUNTY CHILD DEVELOPMENT COUNCIL $1,122,144 ARRA - Early Head Start Name of Project: Early Head Start Program Expansion; Number of Children to be served: 36 infants/toddlers and 6 Pregnant women; Program options offered: Family Child Care and Home Based; Cities or Counties served: Jefferson County, AL; Purpose: To Imple Administration for Children and Families 12/03/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,112,475 Trans-NIH Recovery Act Research Support Epidemiologic studies have demonstrated that exposure to tobacco products is an important risk factor in the progression of chronic kidney disease (CKD). Among the numerous harmful substances found in tobacco, nicotine is one of the highly active compound
This spending item is part of a $1,140,410 allocation. See details
National Institutes of Health 9/17/2009
BIRMINGHAM HEALTH CARE INC $1,081,880 ARRA Health Center Integrated Services Development Initiative[g1] The CIP will allow BHC to make renovations to our buildings, such that equipment, HIT and facility improvements will be evident, as well as allow for additional parking and advanced medical equipment capabilities. These services will ... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,080,321 ARRA Grants for Training in Primary Care Medicine and Dentistry Training and Enhancement Specific Aim 1 : To increase the number of PA graduates capable of providing high- quality health care to individuals with HIV disease and other STDs. Objective 1: To increase the knowledge, comfort and skill of... Show more Health Resources and Services Administration 9/03/2010
SOUTHERN RESEARCH INSTITUTE $1,060,371 The Chemical Biology Consortium (CBC) will identify a cadre of members with the biological expertise and capability to rapidly develop sufficient information both in vitro and in vivo to determine the potential of novel discoveries, from the Cancer Genome
This spending item is part of a $5,000,000 allocation. See details
National Institutes of Health 12/22/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,044,000 Trans-NIH Recovery Act Research Support The Alabama Neuroscience Blueprint Core Center (NS057098) was established in 2006 to provide neuroscience investigators at the University of Alabama at Birmingham (UAB) and participating institutions in the Southern United States access to state-of-the-ar National Institutes of Health 9/13/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,044,000 Trans-NIH Recovery Act Research Support The Alabama Neuroscience Blueprint Core Center (NS057098) was established in 2006 to provide neuroscience investigators at the University of Alabama at Birmingham (UAB) and participating institutions in the Southern United States access to state-of-the-ar National Institutes of Health 9/13/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,000,000 Trans-NIH Recovery Act Research Support This application is in response to NIMH Challenge Area (08) Genomics, Challenge Topic 08-MH-102, Schizophrenia Interactome. Schizophrenia is a devastating mental illness affecting millions in the US and worldwide, with profound human and economic costs. National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $998,903 Trans-NIH Recovery Act Research Support The purpose of this project is to develop and implement fout culturally adaptive distance education courses that can enhance productivity and quality of active U.S.-international research and research training collaborations. The courses are being offere National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $981,624 Trans-NIH Recovery Act Research Support A partnership between the UAB Center for Clinical and Translational Science (CCTS) and 7 other CTSAs to develop a network of networks of practice-based physicians for conducting large-scale simple trials (LSTs) of therapeutics for chronic diseases using l National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $979,412 Trans-NIH Recovery Act Research Support This revision proposes to establish a Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) to: 1) conduct research on the comparative effectiveness of health care delivery strategies within health disparities (HD)
This spending item is part of a $1,400,000 allocation. See details
National Institutes of Health 9/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $930,000 Trans-NIH Recovery Act Research Support In response to the NIH Notice NOT-RR-10-001, the UAB Comprehensive Cancer Center requests an administrative supplement of $895,762 to consolidate its two geographically separated NMR shared facilities of the Cancer Center Support Grant (CCSG) to form a H National Institutes of Health 9/28/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $915,476 Trans-NIH Recovery Act Research Support There are ~5 million heart failure patients in the United States. Over half are estimated to have diastolic heart failure or heart failure with normal or near normal left ventricular ejection fraction. Most diastolic heart failure patients are older adult National Institutes of Health 8/31/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $890,346 Trans-NIH Recovery Act Research Support This two-year study will utilize a randomized design with the active interventions running for 18 months. We have 26 active US sites (27 approved sites with one having to drop out due to lack of indirect cost recovery to pay IRB costs). The 26 sites will
This spending item is part of a $1,349,862 allocation. See details
National Institutes of Health 8/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $866,489 Trans-NIH Recovery Act Research Support The majority of diseases potentially amenable to gene-based therapeutic approaches will likely require systemic vector administration, especially those with vascular involvement such as metastatic cancer, pulmonary arterial hypertension (PAH) and various National Institutes of Health 5/30/2009
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY $851,148 ARRA - Head Start The Head Start Quality Improvement and COLA ARRA funds will provide a 1.84% COLA to staff, improve lighting in some classrooms and pave parking lot at our Fairmont center. Tuition for students taking college courses to obtain their degree will also be pa Administration for Children and Families 6/09/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $823,054 Trans-NIH Recovery Act Research Support In this proposal, we describe a new pathway signaling PMN influx and damage to the airways that may play a role as an initiator or cofactor for chronic obstructive pulmonary disease (COPD). Specifically, chemical or enzymatic breakdown of collagen releas National Institutes of Health 8/07/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $805,521 Trans-NIH Recovery Act Research Support Many acid-base transporters contribute to intracellular and extracellular pH regulation in brain. Electrogenic Na/Bicarbonate Cotransporters (NBCs) are particularly important because they alter pH in response to neuronal activity. While the physiologic si National Institutes of Health 8/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $786,000 Trans-NIH Recovery Act Research Support The proposal is for an administrative supplement to P60 DK-079626 entitled UAB Diabetes Research and Training Center. This research program has been funded by NIDDK since April 1, 2008, and will continue until February 28, 2013. The scope of the administ National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $748,482 Trans-NIH Recovery Act Research Support The proposed program of research will address conservative therapies for OAB and urge incontinence in men. We will plan a 2-stage, randomized clinical trial to examine the effectiveness of behavioral treatment, drug therapy, and combined behavioral and dr
This spending item is part of a $1,064,142 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $741,172 Trans-NIH Recovery Act Research Support The goal of this proposal is to elucidate the molecular mechanisms that control lineage-specific expression or repression of the Ifng locus as a model for understanding factors regulating effector T cell lineage specification. Th1, Th2, and Th17 cells, t National Institutes of Health 6/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $732,292 Trans-NIH Recovery Act Research Support The use of Bacillus anthracis as a bioweapon depends on dispersal of its spores in the environment, entrance into the body, spore uptake by the human host cells, germination of the spores in the host and the pathological consequences of the host response National Institutes of Health 8/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $732,292 Trans-NIH Recovery Act Research Support This proposal has the objective to develop a rational treatment approach for patients with malignant glial-derived brain tumors (glioma). Gliomas and are among the most difficult cancers to treat and typical symptoms include intractable headaches and epil National Institutes of Health 8/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $732,188 Trans-NIH Recovery Act Research Support Tuberculosis (TB) is a severe global health threat and the emergence of multiple drug resistant Mycobacterium tuberculosis (Mtb) strains elevates the threat to a truly alarming state. One third of the world is latently infected with Mtb and the organism National Institutes of Health 7/22/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $732,083 Trans-NIH Recovery Act Research Support Our data indicates that the Dectin-1 beta-glucan receptor is essential for defense against Aspergillus fumigatus, the etiological agent of invasive pulmonary aspergillosis (IPA). We will uncover innate anti-fungal mechanisms mediated by Dectin-1 expressin National Institutes of Health 6/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $732,083 Trans-NIH Recovery Act Research Support During aging, an increasing proportion of total lens proteins becomes water insoluble (WI) either due to aggregation and/or cross-linking. The increased sizes of cross-linked multimers of crystallins become so large that they finally become water insolubl National Institutes of Health 5/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $728,317 Trans-NIH Recovery Act Research Support The Alphavirus genus in the Togaviridae family contains a number of significant human and animal pathogens that are widely distributed on all continents, excluding the Antarctic regions. Some of the alphaviruses, e.g., the Venezuelan, eastern and western National Institutes of Health 5/06/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $684,431 Trans-NIH Recovery Act Research Support Cardiovascular disease (CVD) is the leading cause of death in the western world. However, why some individuals with identical risk factor profiles will go on to develop CVD, whereas others will not, is simply not understood. One explanation is that CVD is
This spending item is part of a $837,468 allocation. See details
National Institutes of Health 8/31/2009
SOUTHERN RESEARCH INSTITUTE $673,602 Trans-NIH Recovery Act Research Support Orthopoxviruses (Smallpox, Monkeypox, etc.) have the potential for causing serious human health problems. Although Smallpox has been eradicated from the wild, it is feared that there may be rogue stockpiles that have the potential to be used as weapons o
This spending item is part of a $2,365,512 allocation. See details
National Institutes of Health 8/01/2009
SOUTHERN RESEARCH INSTITUTE $662,147 Trans-NIH Recovery Act Research Support Highly drug resistant forms of tuberculosis termed multidrug resistant (MDR) and extensively drug resistant (XDR) tuberculosis are on the rise worldwide raising the specter that this disease may once again become virtually incurable.
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/25/2009
JEFFERSON, COUNTY OF $649,977 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Jefferson County Department of Health, Alabama $13.3 Million (Obesity $6.3 Million, Tobacco $7 Million) Jefferson County's tobacco use prevention and cessation initiative will promote changes in policies to reduce smoking oppor... Show more
This spending item is part of a $6,972,663 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $629,011 Trans-NIH Recovery Act Research Support The CFAR Network of Integrated Clinical Systems (CNICS), headquartered at UAB, was funded in September 2006 via the R24 mechanism. This supplement is to fund increased capacity for sample repositorys at UAB and each of the designated CNICS sites through
This spending item is part of a $1,825,789 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $616,291 Trans-NIH Recovery Act Research Support The overall goal of the proposed research is to understand how ErbB signaling regulates Abl/Arg and Src to control cell morphology, adhesion and movements during vertebrate development. Xenopus gastrulation will be used as the model system. ErbB signali National Institutes of Health 8/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $614,565 Trans-NIH Recovery Act Research Support The ARRA grant provides an opportunity to execute a core consolidation that will have enormous benefits for our user-base on a day-to-day basis. This funding allows for purchased of a new peice of major equipment, major upgrades to an exisiting peice, ove National Institutes of Health 7/26/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $592,030 Trans-NIH Recovery Act Research Support The RELIVE (Renal and Lung Living Donors Evaluation) Study is a National Institute of Allergy and Infectious Diseases (NIAID) funded, multi-site effort to determine the long-term risks of live donor nephrectomy 5-50 years later for donors at Mayo Clinic a
This spending item is part of a $861,615 allocation. See details
National Institutes of Health 6/28/2010
SOUTHERN RESEARCH INSTITUTE $587,584 The Chemical Biology Consortium (CBC) will identify a cadre of members with the biological expertise and capability to rapidly develop sufficient information both in vitro and in vivo to determine the potential of novel discoveries, from the Cancer Genome
This spending item is part of a $5,000,000 allocation. See details
National Institutes of Health 12/22/2009
BIRMINGHAM HEALTH CARE INC $580,497 ARRA Health Center Integrated Services Development Initiative[g1] Birmingham Health Care, Inc. will increase our capacity to treat children through the addition of a Pediatrician. The addition of a Pediatrician will result in twice as many children being provided with pediatric health care. Also, B... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $563,672 Recovery Act Comparative Effectiveness Research - AHRQ We propose a UAB T32 program in Comparative Effectiveness Research (CER) to support 4 CER Trainees (2 cohorts of 2 trainees each). This T32 training will be an extension of our very successful T32 in Health Services & Outcomes Research and will b... Show more Agency for Healthcare Research and Quality 7/01/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $556,483 Trans-NIH Recovery Act Research Support Despite many studies that have aimed to alleviate the effects of periodontal and endodontic disease there is still an urgent need to improve the oral health of those suffering from oral infectious or inflammatory diseases. Such translational application o
This spending item is part of a $592,990 allocation. See details
National Institutes of Health 4/28/2011
UNIVERSITY OF ALABAMA AT BIRMINGHAM $528,558 Trans-NIH Recovery Act Research Support The Hemodialysis Fistula Maturation Consortium (HFMC) will conduct a prospective multi-center observational cohort study investigating factors associated with the failure of arteriovenous fistulas (AVFs) to mature. The Data Coordinating Center (DCC) will
This spending item is part of a $542,808 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $520,000 Trans-NIH Recovery Act Research Support The Center for Nanoscale Materials and Biointegration (CNMB) was formally approved by the University of Alabama Board of Trustees in February 2006 as an interdisciplinary research and student-training center focusing (i) on the synthesis and characterizat National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $518,212 Trans-NIH Recovery Act Research Support The AMCRS is a component of the UAB NIH-funded Clinical Trials Unit (CTU). As an MTN site, the AMCRS has been an active participant in Phase 1 and 2 clinical trials assessing candidate vaginal microbicides. The MTN-008 trial will allow the AMCRS to partne National Institutes of Health 8/02/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $516,704 Trans-NIH Recovery Act Research Support The purpose of this project is to develop a multifocal optical coherence microscope (OCM). The proposed OCM will allow noninvasive imaging of unstained biological specimens, with millisecond temporal resolution and sub-cellular spatial resolution in three National Institutes of Health 8/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $500,859 Trans-NIH Recovery Act Research Support The probability of becoming infected upon exposure to HIV varies greatly from one individual to another, so does the rate of disease progression after infection. Determinants of such variable phenotypes include HLA class I (HLA-I) genes that mediate cytot National Institutes of Health 9/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $500,000 Trans-NIH Recovery Act Research Support This award was used to purchase and install 4 pieces of essential equipment in the UAB Fermentation Facility. Three new fermentors have been installed. 1) A BioFlo 415 Fermentor with working volumes of 9.5L - 15.5 L working volume limits will cover the National Institutes of Health 6/10/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $499,105 Trans-NIH Recovery Act Research Support Vital biomedical research and integrity of scientific data depend on excellent animal care. The University of Alabama at Birmingham (UAB) Animal Care and Use Program is committed to the long-term goals of providing and maintaining consistently high qualit National Institutes of Health 8/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $498,939 Trans-NIH Recovery Act Research Support The new NIH Toolbox is an assessment battery developed to standardize evaluations in specific clinical populations for investigations of neurological development and change, disease recovery, and therapeutic interventions. The Toolbox integrates a wide v National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $488,768 Trans-NIH Recovery Act Research Support African-Americans have an approximately 30% to 60% increased incidence of venous thromboembolism (VTE) for unknown reasons.-? The main limitation to studying this disparity is the paucity of African-Americans in most large-scale epidemiological studies.-?
This spending item is part of a $996,126 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $488,236 Trans-NIH Recovery Act Research Support This award is an administrative supplement for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group, specifically to provide supplemental funding for the Immune Activation Project; HIV-1 Project, P1032 and Ancestry Markers
This spending item is part of a $1,204,584 allocation. See details
National Institutes of Health 9/15/2010
JEFFERSON, COUNTY OF $477,823 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Jefferson County Department of Health, Alabama $13.3 Million (Obesity $6.3 Million, Tobacco $7 Million) Alabama ranks as the third unhealthiest state and the second most obese state in the nation. The Jefferson County project is... Show more
This spending item is part of a $6,285,057 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $471,384 Trans-NIH Recovery Act Research Support LKB1 (liver kinase B1) is a serine/threonine kinase that is mutationally inactivated in Peutz-Jeghers syndrome and many cancers. It is estimated that 93% of PJS patients will develop a malignant tumor at an average age of 43 years. LKB1 mutations have als National Institutes of Health 6/17/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $469,212 Trans-NIH Recovery Act Research Support This is an application for an ABI-Sciex 5500 Qtrap to support research by 10 named NIH investigators who are carrying out research on biological pathways, protein complexes, protein post-translational modifications and small biologically active peptides i National Institutes of Health 7/15/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $449,148 Trans-NIH Recovery Act Research Support In contrast to the well studied role of intrinsic factors in tumorigenesis, knowledge regarding the mechanism(s) whereby extrinsic factors, such as the stromal/matrix microenvironment, influence an initiated cell with permanent genetic alterations to tran
This spending item is part of a $591,082 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $442,271 Trans-NIH Recovery Act Research Support Transplantation is the ideal therapy for end stage heart and end stage kidney failure, but allograft survival and function remain suboptimal. This CTOT renewal application will build upon the findings resulting from the previous 4 years of studying biomar
This spending item is part of a $9,955,156 allocation. See details
National Institutes of Health 9/13/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $437,409 Trans-NIH Recovery Act Research Support Bacillus anthracis, the causative agent of anthrax, is a highly pathogenic bacterium considered to be a serious threat as an agent of bioterrorism. The recent use of this bacterium as a terrorist weapon in the United States exposed the need for a more ef National Institutes of Health 6/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $432,156 Trans-NIH Recovery Act Research Support Bacillus anthracis, the causative agent of anthrax, is a highly pathogenic bacterium considered to be a serious threat as an agent of bioterrorism. The recent use of this bacterium as a terrorist weapon in the United States exposed the need for a more ef National Institutes of Health 7/22/2009
County of Jefferson $418,869 Recovery Act Comparative Effectiveness Research - AHRQ StoryGuides: Making Comparative Effectiveness Useful for Vulnerable Patients will culturally adapt the AHRQ Comparative Effectiveness Patient Guides (the Guides) through storytelling (narrative communication), test their use in a randomized tri... Show more
This spending item is part of a $1,487,683 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
UNITED WAY OF CENTRAL ALABAMA, INC. $417,584 ARRA Strengthening Communities Fund ARRA Strengthening Communities Fund Nonprofits Capacity Building Program The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helping low-inco
This spending item is part of a $973,584 allocation. See details
Administration for Children and Families 9/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $410,200 Trans-NIH Recovery Act Research Support The proposed competitive revision represents the natural extension of R01 DE017954 entitled 'Glycosylation and Function of an Oral Streptococcal Adhesin'. This parent grant studies an important streptococcal adhesin Fap1 of Streptococcus parasanguinis we National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $402,719 Trans-NIH Recovery Act Research Support Removal of regional metastasis in head and neck squamous cell carcinoma (HNSCC) requires an extensive procedure with significant morbidity. Current imaging techniques cannot provide real-time information to clinicians or surgeons during diagnostic and the National Institutes of Health 9/01/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $402,625 Trans-NIH Recovery Act Research Support This R21 2-year grant will test our hypothesis that the urine proteome of IgAN patients contains disease-specific biomarkers. We aim to develop a non-invasive procedure for screening and monitoring patients with IgA nephropathy by identifying urinary poly National Institutes of Health 7/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $402,625 Trans-NIH Recovery Act Research Support The immunological of the mucosal extracellular matrix, or stroma, in innate and adaptive immunity has not been critically evaluated and is poorly understood. In view of the newly appreciated importance of the stroma in immunological cross-talk and regula National Institutes of Health 6/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $401,855 Trans-NIH Recovery Act Research Support This program will use several recent findings from clinical research to determine whether progressive multiple sclerosis (MS) significantly responds to a specific form of controlled physical therapy by increasing (1) real-world functional abilities for ex National Institutes of Health 8/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $400,855 Trans-NIH Recovery Act Research Support Mycoplasma pneumoniae is major cause of respiratory infections including community acquired pneumonia, and the organism is an established cause of extrapulmonary complications such as encephalitis. At present three classes of drugs are used to treat M. p National Institutes of Health 7/22/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $394,602 Trans-NIH Recovery Act Research Support The long term goal of this research program is to define the role of the Origin Recognition Complex (ORC) during the cell cycle in eukaryotes. ORC, a heteromeric six-subunit protein complex, is essential for DNA replication, however, its functions extend National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $385,147 Trans-NIH Recovery Act Research Support This proposal will use the interferon-gamma binding protein from ectromelia virus (IFN-gBPECTV) to design new cytokine antagonists and improved research reagents with broad applications to many disciplines. Preliminary structural studies on IFN-gBPECTV h
This spending item is part of a $414,486 allocation. See details
National Institutes of Health 6/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $381,769 Trans-NIH Recovery Act Research Support This supplement accelerates the tempo of research on the three specific aims of the grant by 1) hiring a new research technician who will help work on all three specific aims to move more quickly; 2) hiring a PhD graduate student whose dissertation projec National Institutes of Health 8/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $380,141 Trans-NIH Recovery Act Research Support The overall goal of this study is to understand the mechanism underlying transcription factors specifying osteoclast lineage commitment and differentiation. This proposal is highly significant since elucidating osteoclast lineage commitment and differenti National Institutes of Health 8/08/2011
UNIVERSITY OF ALABAMA AT BIRMINGHAM $366,250 Trans-NIH Recovery Act Research Support The overarching aims of the REGARDS project are to advance the understanding of the causes for the excess stroke mortality among residents of the Southeastern Stroke Belt (SB) and among African Americans (AA) regardless of residence. To accomplish these a National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $366,250 Trans-NIH Recovery Act Research Support The incidence of Juvenile Diabetes, more commonly known as Type 1 Diabetes (T1D), along with other auto-immune related diseases, such as Asthma, are increasing in western-style societies. Of multiple human infectious diseases thought to be associated with National Institutes of Health 6/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $366,146 Trans-NIH Recovery Act Research Support M. tuberculosis (Mtb) is one of the leading causes of death worldwide and claims millions of lives annually. Approximately ~1.7 billion people worldwide are asymptomatically infected with the tubercle bacillus and constitute a major impediment to worldwid National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $364,688 Trans-NIH Recovery Act Research Support Defining the kinetics of molecular interactions between biomolecules has become an essential application for fundamental microbiology and immunology research and translational drug discovery. This shared instrumentation grant requests funding to purchase National Institutes of Health 1/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $364,660 Trans-NIH Recovery Act Research Support This R01 supplement will focus and elaborate on the scientific objective of the parent grant, `Suppression of pathogenic autoantibodies in lupus by inhibition of Activation Induced Cytidine Deaminase, to understand how IL-17 promotes development of autore National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $364,163 Trans-NIH Recovery Act Research Support The UAB Comprehensive Cancer Center is requesting equipment to support a new caBIG compatible Clinical Trials Management System (CTMS). The equipment requested is manufactured by companies, Dell Inc. and Buffalo Technologies Inc., with U.S. headquarters. National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $357,045 Trans-NIH Recovery Act Research Support Chikungunya virus (CHIKV) is an emerging, mosquito-borne alphavirus and potential biological weapon that has caused debilitating, chronic arthralgia in at least 2 million persons in Asia and Africa since 2005. CHIKV was recently placed on the National In
This spending item is part of a $1,933,570 allocation. See details
National Institutes of Health 7/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $349,231 Trans-NIH Recovery Act Research Support While Fc receptors (FcRs) for switched immunoglobulin isotypes have been extensively characterized, an FcR for IgM (Fc-?R) has defied genetic identification. By retroviral expression and functional cloning, we have recently identified a cDNA encoding a National Institutes of Health 7/26/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $341,418 Trans-NIH Recovery Act Research Support This is an application for competitive revision of the currently active RO1 grant Short-Chain Dehydrogenases (SDRs) in Retinol/Sterol Metabolism submitted in response to the Notice NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Co National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $340,686 Trans-NIH Recovery Act Research Support Malignant glioma is the most aggressive and deadly brain tumor in adults. Despite the improvement of imaging technology and surgical removal of the tumors significantly reduces the mortality of malignant glioma, how to enhance the sensitivity to radiation National Institutes of Health 5/15/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $332,781 Trans-NIH Recovery Act Research Support Over-anticoagulation is a strong modifiable risk factor for hemorrhage among warfarin users. To avoid the higher risk of hemorrhage, the American College of Chest Physicians has established guidelines including omission of warfarin doses and administering National Institutes of Health 8/01/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $318,487 Trans-NIH Recovery Act Research Support Driving of the personal vehicle is the primary and preferred mode of travel for older adults in the U.S. More than fulfilling the critically important getting around or mobility function, driving in older adults profoundly impacts health status and thus h National Institutes of Health 9/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $308,264 Trans-NIH Recovery Act Research Support In our currently funded project (R01 AG033906), we propose to: 1) characterize ethnic differences in experimental pain sensitivity, endogenous pain inhibition, clinical pain and pain-related disability among older African Americans and non-Hispanic whites
This spending item is part of a $712,744 allocation. See details
National Institutes of Health 9/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $308,264 Trans-NIH Recovery Act Research Support This proposal expands the research scope of the parent grant (R01 AG033906) by investigating biological markers reflecting predisposing factors for and the stress-related consequences of chronic pain. Consistent with the OppNet priorities, this proposal t National Institutes of Health 9/01/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $305,825 Trans-NIH Recovery Act Research Support Palliative care, a relatively new subspecialty, needs to build its evidence base supporting clinical practice. The Institute of Medicine has identified palliative care as a comparative effectiveness research priority, but increased scientific productivity
This spending item is part of a $7,175,320 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $299,008 Trans-NIH Recovery Act Research Support UAB's Clinical Nutrition Research Unit (CNRU) was inaugurated through NIH funding in 2000 and is also supported by UAB's formal system of University-wide Interdisciplinary Research Centers. Our CNRU fosters multidisciplinary, collaborative approaches to b National Institutes of Health 7/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $296,523 Trans-NIH Recovery Act Research Support Bladder cancer is one of the commonly diagnosed malignancies in both males and females. One approach to control bladder cancer is growth inhibition wherein the disease is prevented, slowed, or reversed significantly by the administration of naturally occu
This spending item is part of a $400,875 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $295,606 Trans-NIH Recovery Act Research Support Tuberculosis is endemic among patients with AIDS and follows an aggressive course with poor localization of myobacteria into granuloma and widespread infection. Granulomas are monocyte rich collections of cells which derive from the circulating periphera National Institutes of Health 2/24/2011
UNIVERSITY OF ALABAMA AT BIRMINGHAM $293,000 Trans-NIH Recovery Act Research Support The Transdisciplinary Geographic Management Program (GMaP) for Region 3, henceforth to be known as the GMaP-3 is designed to develop a systematic and comprehensive strategy for building a state-of-the-art network for the support and efficient management o National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $293,000 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by investigator): This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-HL-104: Assess genetic variation in African Americans and determine its effect on disease. Genome-wide association studi
This spending item is part of a $966,490 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $291,756 Trans-NIH Recovery Act Research Support This administrative supplement request under ARRA is to support additional research assistants for the REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction Study, R01HL080477. The R01 will end April 30, 2011, and is thus eligible National Institutes of Health 8/10/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $274,940 Trans-NIH Recovery Act Research Support We propose the acquisition of Bioptigen, Inc. 840 nm SDOCT Optical Coherence Tomography (OCT) bundled with Phoenix Research Laboratories, Inc. Micron III Retinal Imaging Microscope package (total cost $274,940) for use with both humans and other animals. National Institutes of Health 11/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $267,433 Trans-NIH Recovery Act Research Support This award enhances the original aims set forth in the NIAMS Multidisciplinary Clinical Research Center proposal entitled, Genetic and Molecular Markers of Methotrexate Efficacy and Toxicity in Early RA (Donna K. Arnett, PhD, Principal Investigator), defi National Institutes of Health 9/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $258,762 Trans-NIH Recovery Act Research Support The goal of our studies is to determine the functional role of Runx2 expressed by vascular smooth muscle cells in regulating vascular calcification. In the parent grant, we have designed complementary studies using cultured vascular smooth muscle cells in National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $256,499 Trans-NIH Recovery Act Research Support The goal of this supplemental proposal is to expand the experiments in R01 NS064025A1 entitled, 'Newborn Neurons in the Adult Hippocampal Network' by incorporating new techniques into the study of the survival of adult-generated granule cell (GC) neurons. National Institutes of Health 8/17/2009
SOUTHERN RESEARCH INSTITUTE $252,729 Trans-NIH Recovery Act Research Support Non-muscle invading bladder cancer, due to its extra-systemic and easily accessible location (i.e., surface of the bladder cavity) and its early diagnosis, is one of the least lethal cancers. However, recurrence is common and is sometimes accompanied by p
This spending item is part of a $400,000 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $251,908 Trans-NIH Recovery Act Research Support High density lipoprotein (HDL) and its major protein component apolipoprotein (apo) A-1 exert prominent anti-inflammatory and anti-oxidant effects. Preliminary data presented in the parent application show that the apoA-1 mimetic peptide 4F, whose struct National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $250,000 Trans-NIH Recovery Act Research Support Purchase of the MicroCal AutoITC System to support NIH-funded projects from PIs across the UAB campus and Emory who require a quantitative and complete thermodynamic evaluation of the molecular interactions of biological macromolecules. National Institutes of Health 11/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $246,417 Trans-NIH Recovery Act Research Support This ARRA award encompasses two separate requests that were funded in support of the UAB SPORE in Neurological Cancer, P50CA097247. A $146,417 request was awarded to fund basic and translational research efforts and a $100,000 request was awarded to purc National Institutes of Health 9/09/2009
JEFFERSON COUNTY COMMITTEE FOR ECONOMIC OPPORTUNITY $225,000 ARRA - Early Head Start Award Title: JCCEO ARRA Early Learning Mentor Coach Project Award Description and Purpose: The JCCEO ARRA Early Learning Mentor Coach grant award provides funding to assist Head Start educational leadership and support staff who currently are in the posit Administration for Children and Families 9/16/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $224,936 Trans-NIH Recovery Act Research Support Idiopathic pulmonary fibrosis (IPF) is characterized by fibroblast and myofibroblastic foci, and has excessive extracellular matrix protein accumulation. Focal-adhesion-kinase-related-non-kinase (FRNK) mediates integrin-mediated cell migration. This propo National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $220,849 Trans-NIH Recovery Act Research Support This supplement will augment the activities and aims supported by the parent grant (5U10HD041261). The University of Alabama at Birmingham (UAB) has been a clinical site for 9 years in the Pelvic Floor Disorders Network (PFDN), a clinical research network National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $219,750 Trans-NIH Recovery Act Research Support This one year ARRA award provided us with bridge funding to continue a project that has been ongoing in our laboratory for over 10 years. The main goals of this project have been to: determine how the CFTR channel (i.e., the ion channel that is defective National Institutes of Health 1/11/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $219,750 Trans-NIH Recovery Act Research Support Growth hormone (GH) regulates postnatal growth and metabolism in humans and other vertebrates. GH signaling begins with its interaction with cell surface GH receptor (GHR), a transmembrane glycoprotein cytokine receptor family member. GHR encodes no int National Institutes of Health 4/12/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $219,719 Trans-NIH Recovery Act Research Support This award is a supplement 3R01GM033143-22S1 ARRA, which is entitled Long Range DNA Interactions in Mu and Bacterial DNA. The start date is 09/30/2009 and this project will end on 08/31/2011. The full amount to be distributed over 2 years is $219,719. National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $212,846 Trans-NIH Recovery Act Research Support This supplemental application for the UAB-UCSD O'Brien Core Center for Acute Kidney Injury (AKI)(1P30 DK079337) in response to NIDDK FY2009 Program for Administrative Supplements Utilizing Recovery Act Fund (NOT-OD-09-056) is designed to facilitate new an
This spending item is part of a $363,337 allocation. See details
National Institutes of Health 8/10/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $211,300 Trans-NIH Recovery Act Research Support In order to make these studies possible, the scientific community will require the repeated participation of a large numbers of normal subjects who carry polymorphisms of interest and are willing to be studied. This proposal will make such a population re
This spending item is part of a $2,490,569 allocation. See details
National Institutes of Health 9/30/2009
SAMFORD UNIVERSITY $206,120 ARRA - Nurse Faculty Loan Program Samford University utilizes the American Recovery Reinvestment Act (ARRA) funds available to the Nursing Faculty Loan Program (NFLP) to support students enrolled in the Ida V. Moffet School of Nursing's advanced education nursing programs: MSN (Educator T Health Resources and Services Administration 8/10/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $205,740 Trans-NIH Recovery Act Research Support The Transgenic Mouse Facility (TMF) was established in 1991 as a centralized core for the efficient production of transgenic animal models for UAB investigators. The shared facility is supported primarily by P30 Grants maintained by University Centers (Co National Institutes of Health 3/11/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $204,869 Trans-NIH Recovery Act Research Support The University of Alabama at Birmingham (UAB) is Alabama's largest employer, with more than 18,000 faculty and staff at the university and in the health system, and is responsible for 52,900 full-time equivalent jobs within the university and community National Institutes of Health 8/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $204,401 Trans-NIH Recovery Act Research Support Monitoring is a periodic measurement that guides the management of a chronic or recurrent condition. It aims to detect departure from the conditions baseline, establish the response to treatment, and detect the need to adjust treatment. Our goal is to ide National Institutes of Health 9/11/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $202,813 Trans-NIH Recovery Act Research Support Posttranslational histone modifications play important roles in regulating chromatin structure and function. In my RO1 GM081489 grant, we propose to thoroughly characterize the H2A deubiquitinase Ubp-M, with goals of determining the roles and elucidating National Institutes of Health 8/31/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $202,406 Trans-NIH Recovery Act Research Support This request for an Administrative supplement under the Recovery Act will generate a new position for a mid-career Research Associate who is an expert in Ca2+= imaging in glial cells. This hire will allow us to extend the originally proposed studies on th National Institutes of Health 8/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $201,173 Trans-NIH Recovery Act Research Support The overall goal of the ongoing studies is to define the structure/function relationships of a family of paired Ig-like receptors of activating (PIR-A) and inhibitory (PIR-B) isoforms that we identified in mice. The hypothesis that PIR-A and PIR-B play r National Institutes of Health 8/09/2010
DISCOVERYBIOMED, INC. $200,000 Trans-NIH Recovery Act Research Support This Phase 1 SBIR award was a Catalyst award under ARRA. This award was garnered based upon a program to discover novel botanical or phytochemical-derived chemicals that will be developed an future anti-inflammatory drugs for a series of chronic respirato National Institutes of Health 4/01/2010
BIRMINGHAM HEALTH CARE INC $191,250 ARRA Health Center Integrated Services Development Initiative[g1] The purpose of the HCCN Alabama HIT Smart Card Innovation Project is to implement a Health Technology Innovation for the most vulnerable residents in the state of Alabama by way of the Smart Card. The Smart Card stores the patient's Me... Show more Health Resources and Services Administration 9/14/2009
SOUTHERN RESEARCH INSTITUTE $188,036 Trans-NIH Recovery Act Research Support Orthopoxviruses (Smallpox, Monkeypox, etc.) have the potential for causing serious human health problems. Although Smallpox has been eradicated from the wild, it is feared that there may be rogue stockpiles that have the potential to be used as weapons o
This spending item is part of a $2,365,512 allocation. See details
National Institutes of Health 8/01/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $187,428 Trans-NIH Recovery Act Research Support This is an application in response to notice NOT-OD-09-056, requesting a supplement to grant 5R01AG031722-32, which focuses on the role of epigenetic mechanisms in A-betas effects on plasticity and memory formation. This supplement application requests s National Institutes of Health 9/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $187,373 Trans-NIH Recovery Act Research Support We intend to enhance and expand the U54 UAB Community Outreach Program entitled Increasing Minority Participation in Clinical Trials (IMPaCT) by providing the opportunity for AA patients at Cooper Green Mercy Hospital, a safety-net county hospital treatin
This spending item is part of a $267,359 allocation. See details
National Institutes of Health 8/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $184,843 Trans-NIH Recovery Act Research Support The purpose of the American Recovery and Reinvestment Act (ARRA) funded Administrative Supplement is to hire one new research staff member to advance research supported by the parent grant 5R01HL085561-04 (Heart Failure, Chronic Kidney Disease, and Renin National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $184,627 We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr
This spending item is part of a $2,725,275 allocation. See details
National Institutes of Health 9/27/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $184,147 Trans-NIH Recovery Act Research Support Protein translocations across mitochondria membranes play critical roles in mitochondria biogenesis. The protein transports from the cell cytosol to the mitochondria matrix are carried out by the translocase of the outer membrane (TOM) complex and the tra National Institutes of Health 3/10/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $183,868 Trans-NIH Recovery Act Research Support Common variable immunodeficiency (CVID) is a clinical diagnosis given to patients who suffer with am unexplained deficiency of serum immunoglobulins. The presenting complaint for most CVID patients is recurrent sinopulmonary infections. Among our clinic National Institutes of Health 7/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $180,117 Trans-NIH Recovery Act Research Support We are establishing C. elegans as a model for studying prostaglandin metabolism, genetic regulation, and biological functions. Using a combination of genetic analyses, in vivo bioactivity assays, and liquid chromatography-tandem mass spectrometry, we hav National Institutes of Health 7/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $177,568 Trans-NIH Recovery Act Research Support The overarching study was initiated because the adverse neural consequences of abnormal vision have been well researched, but under-detection of risk factors for amblyopia is still common. Gaps in screening in the medical home are due to children missing National Institutes of Health 8/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $170,176 Trans-NIH Recovery Act Research Support Onchocerciasis is a debilitating disease caused by infection with the parasite Onchocerca volvulus. The public health importance of onchocerciasis has been recognized by the international community, which has sponsored several programs whose goal (dependi
This spending item is part of a $800,000 allocation. See details
National Institutes of Health 8/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $169,579 Trans-NIH Recovery Act Research Support This is an application for administrative supplement to my currently active RO1 grant Short-Chain Dehydrogenases (SDRs) in Retinol/Sterol metabolism. The overall goal of this project is to understand the mechanisms that regulate the steady-state levels of National Institutes of Health 7/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $165,251 Trans-NIH Recovery Act Research Support This revised competing renewal application continues research aimed at understanding resolution processes in problem drinkers and promoting resolution efforts in the community. The research is guided by behavioral economics, which provides a powerful fram National Institutes of Health 7/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $164,631 Trans-NIH Recovery Act Research Support North American AIDS Cohorts Collaboration on Research and Design A disturbing increase in the incidence of non-AIDS-defining conditions including renal disease, metabolic and cardiovascular disease, and malignancies has been observed in recent years, and
This spending item is part of a $7,312,062 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $164,032 Trans-NIH Recovery Act Research Support The significant contribution of the Administrative Supplement would be to provide for the long-term hiring of a Research Assistant at UAB which will allow us to increase the rate at which we record using fMRI and electrophysiology in this study. This will
This spending item is part of a $252,134 allocation. See details
National Institutes of Health 9/30/2009
COMMUNITY ACTION ASSOCIATION $160,000 ARRA - Community Services Block Grant The project activities for the two year period were designed to: (1) Develop a CSBG Recovery Act Statewide Strategic Plan, (2) Advance a Statewide ARRA Communication Plan, (3) Create an electronic, publically accessible Alabama ARRA Report, and (4) Co-con Administration for Children and Families 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $158,059 Recovery Act Comparative Effectiveness Research - AHRQ Patients with critical conditions such as cardiac arrest or major trauma often depend on prehospital emergency medical services (EMS) for life-saving care. Nevertheless, the evidence base for that care, particularly as it relates to transitions b... Show more
This spending item is part of a $1,397,861 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $154,223 Trans-NIH Recovery Act Research Support UAB is one of Americas premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earning more than $360 million per year in contract and grant support, with more than $250 million per year of extramural National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $153,922 Trans-NIH Recovery Act Research Support Linkage disequilibrium (LD, the non-random association of alleles at two or more loci) provides valuable information for detecting genetic variations that are responsible for complex human diseases such as hypertension, diabetes, obesity, and stroke. Hapl National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $150,705 Trans-NIH Recovery Act Research Support Argatroban, a thrombin inhibitor, has been studied in the setting of both coronary perfusion as well as acute ischemic stroke. Since the majority of ischemic stroke patients may not benefit from rt-PA alone, the combination of thrombolytics with anticoagu
This spending item is part of a $1,096,944 allocation. See details
National Institutes of Health 9/22/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $149,894 Trans-NIH Recovery Act Research Support Under SEPA funding, we created a very effective school year experience for about 3,000 Birmingham area middle school students each year. Our programs are reaching underserved populations because most (98%) of the students in the Birmingham City School sy National Institutes of Health 9/07/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $148,326 Recovery Act Comparative Effectiveness Research - AHRQ Bipolar is a severe and lifelong illness affecting 4.5% of the population ? about 14 million people in the U.S. It is one of the top 10 most disabling medical conditions worldwide according to the World Health Organization. Traditionally, the moo... Show more
This spending item is part of a $9,784,863 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $147,589 Trans-NIH Recovery Act Research Support This supplement will streamline our laboratory protein production and protein analysis pipelines that are currently impeding scientific progress on our parent grant: AI43700-08 entitled Structure Studies on Proteins that Modulate IL-10 Action. The centra National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $147,016 Trans-NIH Recovery Act Research Support Fulfilling ARRA goals we recruit two scientists to boost University of Alabama at Birmingham important health related research and to make a positive impact on the local economy. Hiring two senior scientists in order to boost our research to achive specif National Institutes of Health 8/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $146,458 Trans-NIH Recovery Act Research Support Currently 5FU/LV/oxaliplatin (FOLFOX) is the most commonly used therapeutic agent for colorectal cancer (CRC) treatment (Rx). The anti-tumor activity of FOLFOX depends on its ability to induce apoptosis by damaging the DNA and by altering the expression o National Institutes of Health 7/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $146,447 Trans-NIH Recovery Act Research Support DESCRIPTION: Spinal cord injury (SCI) leads to a profound reduction in physical activity, resulting in a low exercise capacity and increased risk of mortality. Of note, physical inactivity is approaching tobacco as the leading actual cause of death in the National Institutes of Health 8/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $146,438 Trans-NIH Recovery Act Research Support Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder resulting in progressive respiratory insufficiency and lung fibrosis with fatal outcome. The pathogenesis of IPF remains unclear. Focal-adhesion-kinase-related non-kinase (FRNK) is an endogeno National Institutes of Health 5/08/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $146,438 Trans-NIH Recovery Act Research Support Idiopathic Pulmonary Fibrosis (IPF) is a deadly disease without a clearly-defined etiology. Because the incidence increases with age, it is plausible that environmental effects may be important. Recent data indicate re-expression of developmental gene sig National Institutes of Health 5/08/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $146,417 Trans-NIH Recovery Act Research Support Complement is important part of the innate immune system and is arguably best known for its ability to lyse bacteria, enveloped viruses and eukaryotic cells through a macro-molecular structure known as the membrane attack complex (MAC). The MAC is compos National Institutes of Health 6/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $138,285 Trans-NIH Recovery Act Research Support This administrative supplement to our UAB Infectious Diseases Training grant will expand and enhance our ability to train investigators in Comparative Effectiveness Research (CER). The UAB ID division has been a leader in CER in HIV, STD, and Opportunisti National Institutes of Health 6/21/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $136,311 Trans-NIH Recovery Act Research Support We have advanced the development of an imaging method for CRAds based upon capsid incorporation of imaging motifs. This capacity allowed assessments of CRAd parameters in vivo related to viral persistence. On the basis of these findings, we sought to exp National Institutes of Health 8/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $133,734 ARRA - Nurse Faculty Loan Program $133,734 plus 9% matching from institution given to doctotal nursing completing degrees with course work on instruction, curriculum development and evaluation. Health Resources and Services Administration 6/14/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $133,415 Trans-NIH Recovery Act Research Support This request for an administrative supplement for grant number R21 AT004661-01 is to accelerate progress in the evaluation of putative urinary peptide biomarkers of puberty discovered by initial proteomics analysis of urines obtained from the GRLS study i National Institutes of Health 9/11/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $132,624 Trans-NIH Recovery Act Research Support We plan a multi-center study to accurately describe the natural history of late kidney transplant failure, and to dissect out individual entities leading to late deterioration of function and to graft loss. Previous studies, and the current literature, at
This spending item is part of a $1,128,568 allocation. See details
National Institutes of Health 6/28/2010
County of Jefferson $130,136 Trans-NIH Recovery Act Research Support This revision proposes to establish a Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) to: 1) conduct research on the comparative effectiveness of health care delivery strategies within health disparities (HD)
This spending item is part of a $1,400,000 allocation. See details
National Institutes of Health 9/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $128,755 Trans-NIH Recovery Act Research Support The aim overall of this application is to enhance capacity to perform early developmental interventions and neurodevelopmental assessments in order to conduct collaborative research that will evaluate a program of early developmental intervention to reduc
This spending item is part of a $222,039 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $127,193 Trans-NIH Recovery Act Research Support On behalf of the Reproductive Medicine Network (RMN), we, as the Data Coordination Center, submit this request in response to NIH announcement NOT-OD-09-056 for a Recovery Act administrative supplement. We will use the supplement to field a comparative ef
This spending item is part of a $7,565,277 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $126,153 Trans-NIH Recovery Act Research Support This supplement request involves molecular biology, protein purification and crystallization training for high school and undergraduate students plus one high school science teacher. Participants will work under the guidance of university investigators ( National Institutes of Health 7/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $125,159 Trans-NIH Recovery Act Research Support This study seeks to determine the molecular basis of regulation of the JAK/STAT pathway in glial cells, to better understand the circuitry that goes awry in neuroinflammatory disorders such as Multiple Sclerosis. One Specific Aim is proposed in this Admi National Institutes of Health 9/15/2009
JEFFERSON COUNTY CHILD DEVELOPMENT COUNCIL $124,324 ARRA - Head Start Head Sart ARRA COLA & Quality Improvement Administration for Children and Families 7/02/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $123,480 Trans-NIH Recovery Act Research Support Several messages can use an alternative mechanism of initiating translation when cap-dependent translation is down regulated. These messages contain internal ribosome entry sites within their 5'untranslated region. The mRNAs that contain IRESs encode pr National Institutes of Health 1/15/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $120,294 Trans-NIH Recovery Act Research Support While the African-American population has large differences in various neoplastic disease processes especially in neoplastic disease of the breast and prostate, very few African-Americans have been recruited into graduate programs for the Doctor of Philos National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $116,041 ARRA - Public Health Traineeship Program Traineeship funding is requested to enhance the school's ability to recruit, retain and prepare with graduate degrees in public health, the highest quality students for career positions in those fields in short supply of professionals including biostatist Health Resources and Services Administration 9/03/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $114,953 Trans-NIH Recovery Act Research Support The overall goal of the 3-years parent R01 grant, which ended Aug 31st, 2009 and currently in a first year unfunded extension , is a better understanding of the neural substrate of primate eye movements in depth, which require unequal rotations of the two National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $110,316 Trans-NIH Recovery Act Research Support The Epilepsy Phenome/Genome Project is investigating how genes influence the phenotypes of common and rare epilepsies and has proposed to accelerate collection of phenotypic information by hiring a research assistant at each clinical center.
This spending item is part of a $1,558,189 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $110,050 Trans-NIH Recovery Act Research Support The current project is to collect data from young adults with normal eyes, to enhance analysis of data from the existing COMET/COSMICC cohort, a group of ethnically diverse, myopic young adults with 12 years of standardized, reliable measurements of refra National Institutes of Health 9/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $109,447 Trans-NIH Recovery Act Research Support Regulation of mRNA stability plays a critical role in the control of gene expression. Dysregulated mRNA turnover has been implicated in various pathological processes. Understanding the regulation of mRNA decay should provide insights into the pathogenesi National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $108,000 Trans-NIH Recovery Act Research Support The career objective of the K23 candidate is to become a rheumatic disease epidemiologist. In the context of mentored research, Dr. Curtis will examine the incidence, risk factors, and outcomes related to osteoporosis, with an emphasis on African American National Institutes of Health 9/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $108,000 Trans-NIH Recovery Act Research Support This application proposes a training plan to develop Laura E. Dreer, PhD into an independent patient-oriented researcher specializing in investigations of psychological-based treatment interventions for persons with low vision. Dr. Dreer is a licensed cli National Institutes of Health 9/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $107,239 Trans-NIH Recovery Act Research Support The science of this proposal is well aligned with a focus topic identified by the NIMH; enhancing risk prediction through secondary data analysis. The risk prediction rule developed through K23MH082641 will be derived and internally validated at a single National Institutes of Health 7/16/2009
SOUTHERN RESEARCH INSTITUTE $104,352 Trans-NIH Recovery Act Research Support Bladder cancer is one of the commonly diagnosed malignancies in both males and females. One approach to control bladder cancer is growth inhibition wherein the disease is prevented, slowed, or reversed significantly by the administration of naturally occu
This spending item is part of a $400,875 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $100,402 Trans-NIH Recovery Act Research Support The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $100,000 Trans-NIH Recovery Act Research Support The long-term goal of this project is to understand the molecular mechanisms responsible for the regulation of mitochondrial pyruvate dehydrogenase complex. The reaction catalyzed by pyruvate dehydrogenase complex plays a central role in general metabolis National Institutes of Health 12/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $100,000 Trans-NIH Recovery Act Research Support The overall goal of the parent grant is to define the role of Erythroid Krupple-Like Factor (EKLF) in globin gene switching during development. We have deleted the 50 bp upstream enhancer of the EKLF gene in ES cells and demonstrated that fetal globin ge National Institutes of Health 1/18/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $99,999 Trans-NIH Recovery Act Research Support The University of Alabama at Birmingham (UAB) has been a clinical site for 7 years in the Urinary Incontinence Treatment Network (UITN), a clinical research network, including nine clinical centers (CC) and a data coordinating center (DCC), established by National Institutes of Health 2/26/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $99,870 Trans-NIH Recovery Act Research Support B lymphocytes are required for host defense against infectious pathogens but abnormal activation of B cells can lead to autoimmunity. Thus, B cells are important in a wide range of physiologic and pathophysiologic processes. Mature B cells in the spleen e National Institutes of Health 6/29/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $99,592 Trans-NIH Recovery Act Research Support CAMUS is an 11 site placebo controlled clinical trial testing the efficacy of saw palmetto in the treatment of benign prostatic hyperplasia. The CAMUS Data Coordinating Center (DCC) provides infrastructure support and is responsible for: 1. Coordinating t National Institutes of Health 8/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $99,547 Trans-NIH Recovery Act Research Support Growth hormone (GH) regulates postnatal growth and metabolism in vertebrates in an endocrine fashion. In addition, recent studies suggest roles for autocrine-derived GH and for an intact GH axis in formation and behavior of cancers in animals. GH receptor National Institutes of Health 12/03/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $98,944 Trans-NIH Recovery Act Research Support Amerindians in Chile likely migrated from Asia thousands of years ago, and East Asian strains of H. pylori produce a more pathogenic CagA motif than European strains. A substantial portion of Amerindians live in isolated, relatively less hygienic rural c National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $95,800 Trans-NIH Recovery Act Research Support 'Several projects were funded under this award. Project #1 - To evaluate and qualify new assays for infant diagnosis and viral load monitoring of HIV under standard laboratory conditions prior to field testing. Outputs: 1 or 2 manuscripts Delivera
This spending item is part of a $721,615 allocation. See details
National Institutes of Health 7/20/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $95,800 Trans-NIH Recovery Act Research Support 'Several projects were funded under this award. Project #1 - To evaluate and qualify new assays for infant diagnosis and viral load monitoring of HIV under standard laboratory conditions prior to field testing. Outputs: 1 or 2 manuscripts Delivera
This spending item is part of a $721,615 allocation. See details
National Institutes of Health 7/20/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $95,113 Trans-NIH Recovery Act Research Support The Pediatric HIV/AIDS Cohort Study (PHACS) was established to evaluate 2 critical areas in pediatric HIV research: the long-term safety of fetal and infant exposure to prophylactic antiretroviral (ART) chemotherapy, and the effects of prenatally acquired
This spending item is part of a $1,888,985 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $95,029 Trans-NIH Recovery Act Research Support This award will support a Health Services Administration PhD candidate at UAB. With support from NHLBI Recovery Act Funds, the candidate will defend her dissertation and obtain her PhD within the next 12 months, and then she will work with the PI as a po National Institutes of Health 8/10/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $94,450 Trans-NIH Recovery Act Research Support Kidney failure is a major cause of morbidity and mortality in the United States and worldwide. Transcriptional regulation of podocyte diseases is not as yet well understood. Our long term goal is to define the precise mechanisms of proteinuria and glomeru National Institutes of Health 11/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $94,259 ARRA - Nurse Faculty Loan Program $94,259.00 plus 9% cost share all to be given to doctoral students completing degrees. Health Resources and Services Administration 8/10/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $93,602 Trans-NIH Recovery Act Research Support Huntington's Disease (HD) is an autosomal dominant neurological disorder caused by the inheritance of a CAG repeat greater than 36 in length in exon 1 of a gene of unknown function, huntingting. There is no known cure for this lethal neurological disorde National Institutes of Health 8/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $93,365 Trans-NIH Recovery Act Research Support This supplemental request complements the parent grant in that the supplement proposes to create a CRAd that has greater oncolytic potency than the CRAd that was previously considered for imaging modification in the parent grant. The oncolytic potency of
This spending item is part of a $344,729 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $89,940 Trans-NIH Recovery Act Research Support Cellular adhesion molecules (CAMs) may play a key role in atherosclerotic development. Soluble intracellular adhesion molecule (ICAM)-1 relates to clinical coronary heart disease in older people, mostly in case-control designs. Plausible pathways have bee
This spending item is part of a $1,537,979 allocation. See details
National Institutes of Health 6/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $88,366 Trans-NIH Recovery Act Research Support This K08 Award focuses on the role of Extracellular matrix metalloprotease inducer (EMMPRIN or CD147) as a tumor cell surface molecule that promotes tumor-stromal interactions in head and neck squamous cell carcinoma (HNSCC). As outlined in the first two National Institutes of Health 9/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $85,908 Trans-NIH Recovery Act Research Support The overall goal of the original R01 application (CA098932-06) is to identify potential prognostic markers of CRCs. The specific objectives of this funded grant were to develop strategies in assessing the clinical outcome of CRCs based on the underlying h National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $85,000 Trans-NIH Recovery Act Research Support Heat-shock protein 40 (Hsp40) plays essential roles in cell physiology since it cooperates with Hsp70 and Hsp90 to facilitate protein folding. The goal of the parent grant is to carry out X-ray crystallographic studies on Hsp40 to uncover the mechanisms b National Institutes of Health 12/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $84,511 Trans-NIH Recovery Act Research Support We submitted this administrative supplement in response to the request for administrative supplements through the American Recovery and Reinvestment Act (ARRA). With the funds we are:1. Accelerating science by adding comparative effectiveness implementa
This spending item is part of a $317,255 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $83,140 Trans-NIH Recovery Act Research Support CYCORE: CYBERINFRASTRUCTURE FOR COMPARATIVE EFFECTIVENESS RESEARCH
This spending item is part of a $3,866,878 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $83,089 Trans-NIH Recovery Act Research Support This study seeks to elucidate the mechanistic basis of immune responses to factor VIII (FVIII) in some but not all hemophilia A (HA) patients and the increased risk of HA patients with black African ancestry for developing that complication following ther
This spending item is part of a $6,507,463 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $82,033 Trans-NIH Recovery Act Research Support Silent Cerebral Infarct (SCI) is the most common cause of severe neurological disease in children with sickle cell anemia, occurring in 22% of this population prior to their 18th birthday. The overall goal of this trial is to determine whether blood trans
This spending item is part of a $1,571,661 allocation. See details
National Institutes of Health 9/07/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $81,713 Trans-NIH Recovery Act Research Support This Administrative Supplement for Summer Research Experiences for Students and Science Educators supports undergraduate students for the Summers of 2009, 2010, 2011, and 2012. The parent grant seeks to determine the role of Suppressor Of Cytokine Signal National Institutes of Health 7/19/2009
County of Jefferson $79,986 Trans-NIH Recovery Act Research Support We intend to enhance and expand the U54 UAB Community Outreach Program entitled Increasing Minority Participation in Clinical Trials (IMPaCT) by providing the opportunity for AA patients at Cooper Green Mercy Hospital, a safety-net county hospital treatin
This spending item is part of a $267,359 allocation. See details
National Institutes of Health 8/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $79,814 Trans-NIH Recovery Act Research Support HIV infection in the US occurs disproportionately among racial/ethnic minority youth in urban areas. The Adolescent Trials Network for HIV/AIDS Interventions (ATN) has developed a community-based primary HIV prevention infrastructure in 13 cities anchored
This spending item is part of a $6,833,921 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $78,643 Trans-NIH Recovery Act Research Support The University of Alabama at Birmingham (UAB) is Alabamas largest employer, with more than 18,000 faculty and staff at the university and in the health system, and is responsible for 52,900 full-time equivalent jobs within the university and the communit National Institutes of Health 7/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $75,084 Trans-NIH Recovery Act Research Support This project is designed to complete the scientific planning and administrative activities that are required to conduct a clinical trial on the efficacy of lifestyle intervention to treat obese men with erectile dysfunction (ED). ED is a significant publ
This spending item is part of a $726,805 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $74,070 Trans-NIH Recovery Act Research Support The proposal is for an administrative supplement to R01 DK-038765 (PI: Garvey) entitled Mechanisms of Human Resistance. This program has been continuously funded by NIDDK since 7/1/1988, and the current competitive renewal extends from 7/1/2006 to 6/ National Institutes of Health 12/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $73,250 Trans-NIH Recovery Act Research Support This Administrative Supplement will accelerate the tempo of scientific research by providing funds that will allow us to capitalize on recent data acquired and published by our laboratory. The observation that Hck/Fgr/Lyn-/- mice were better at clearing P National Institutes of Health 7/16/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $73,249 Trans-NIH Recovery Act Research Support The study of epigenetic variation is an essential complement to conventional genetic disease studies, since the phenotypic consequence of DNA sequence depends on its epigenetic context. Unlike sequence variation, epigenetic marks, i.e. chemical modificati National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $71,200 Trans-NIH Recovery Act Research Support Despite significant advances in the treatment of cancer over the past several decades, there are no longterm effective therapies for glioblastoma multiforme GBM. The aims of the project have focused on the use of expanded/activated T cells as adjuvant im National Institutes of Health 8/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $64,409 ARRA - Head Start The ARRA funds were awarded to the UAB Early Head Start Program to help retain staff and enhance the program. The UAB Early Head Start Program was funded in 1998 to serve 88 infants and toddlers and their families or women who are pregnant, who are chall Administration for Children and Families 7/15/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $62,500 Trans-NIH Recovery Act Research Support The overall goal of this grant is to assess how disruption of the cilium results in hyperphagia induced obesity. We proposed three aims in the parent proposal. The first is to analyze the obesity phenotype associated with cilia mutant mice. The goal of t National Institutes of Health 12/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $56,603 Trans-NIH Recovery Act Research Support Aim 1: Define mechanisms by which TLR2 activation modulates endothelial cell (EC) expression of coagulation pathway factors in vitro. We defined the role of MAP kinases and NF-kB in EC TLR2 signaling to inflammatory mediators and PAI-1. Notable findings w
This spending item is part of a $687,893 allocation. See details
National Institutes of Health 6/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $56,420 Trans-NIH Recovery Act Research Support This proposal is submitted in response to RFA-DK-06-501 for continuation of the Urinary Incontinence Treatment Network (UITN) Clinical Center at University of Maryland Baltimore (UMB). Phase II will focus on conduct of the Trial of Mid-Urethral Slings (TO
This spending item is part of a $190,000 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $56,299 Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation. See details
National Institutes of Health 9/14/2009
American Cancer Society, Mid-South Division, Inc. $55,655 Trans-NIH Recovery Act Research Support We propose to conduct a genome-wide association study to identify loci involved in endometrial cancer causation. We plan to utilize studies with available biospecimens, 6 cohorts from the NCI Cohort Consortium and 7 case-control studies, within the NCI Ep
This spending item is part of a $4,309,389 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $53,826 Trans-NIH Recovery Act Research Support This administrative supplement will enhance the activities and aims approved by the parent grant (5 K24 DK068389). It will allow us to continue research initiatives, as well as the clinical care offered through the UAB Genitorectal Disorders clinic. The a National Institutes of Health 12/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $52,396 Trans-NIH Recovery Act Research Support Purchase of three items of equipment necessary to studies pertaining to the mechanism of action of PspA and related pneumococcal virulence proteins currently funded by NIH project AI21548. The equipment will not only enhance our ability to reach the goal National Institutes of Health 9/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $50,000 Trans-NIH Recovery Act Research Support This project is to participate in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) by providing appropriate clinical and informatics expertise in scheduled mee National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $50,000 Trans-NIH Recovery Act Research Support We requested funds to purchase an Ultra High Performance Liquid Chormatography (UHPLC), one of the newest analytical tools in liquid chromatography used for drug quantitation. The overall scope of the parent grant is to determine whether fluctuations in s National Institutes of Health 9/17/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $50,000 Trans-NIH Recovery Act Research Support In accordance with the objectives of the American Recovery and Reinvestment Act of 2009 (ARRA) Administrative Supplements, this supplement application will: 1) promote new job creation, and 2) accelerate both the tempo and the achievement of research. Sup National Institutes of Health 9/11/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $50,000 Trans-NIH Recovery Act Research Support In accordance with the objectives of the American Recovery and Reinvestment Act of 2009 (ARRA) Administrative Supplements, this supplement application will: 1) promote new job creation, and 2) accelerate both the tempo and the achievement of research. Sup National Institutes of Health 8/30/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $49,998 Trans-NIH Recovery Act Research Support This administrative supplement award began in year 4 of the parent project (K02 AI076123). The funds will contribute to: (i) the hiring of a new graduate assistant for data management and data analyses, (ii) the retention of a newly hired, full-time rese National Institutes of Health 8/09/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $49,431 Trans-NIH Recovery Act Research Support Initially funded for a one-year period, the administrative supplement award, K02-AI076123-S1, has received a 6-month no-cost extension that started on July 1, 2010. Despite a modest budget ($49,431 in total costs), this award has contributed to: a) the p National Institutes of Health 9/11/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $49,392 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
MAIN STREET BIRMINGHAM, INC. $49,000 ARRA Strengthening Communities Fund ARRA Strengthening Communities Fund Nonprofits Capacity Building Program The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helping low-inco
This spending item is part of a $973,584 allocation. See details
Administration for Children and Families 9/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $48,352 Trans-NIH Recovery Act Research Support The goal of this project is to determine the functional adaptation and consequences of salt intake on endothelial cell function in the vasculature and the kidney. By defining the signal transduction pathway in endothelial cells, this application will prov National Institutes of Health 9/07/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $46,444 Trans-NIH Recovery Act Research Support The University of Alabama at Birmingham (UAB) is Alabama's largest employer. Eight in every 100 jobs in the Birmingham area, and 2.8 jobs in every 100 jobs in Alabama, are related to UAB. UAB's overall economic impact in the Birmingham metro area exceeds National Institutes of Health 12/08/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $46,176 Trans-NIH Recovery Act Research Support Research to be conducted under the ARRA mechanism will accelerate the scientific tempo of a trial designed to understand the efficacy, mechanisms, and cost-effectiveness of alternative resuscitation strategies for septic shock. Trial recruitment will be e
This spending item is part of a $2,314,994 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $45,727 Trans-NIH Recovery Act Research Support The award will be used to purchase equipment necessary to read ELISAs, as well as BCA assays for Western blotting, as part of the biochemical analyses proposed in Specific Aims 3 and 4 of the parent grant. National Institutes of Health 1/18/2010
HISPANIC INTEREST COALITION OF AL $45,000 ARRA Strengthening Communities Fund ARRA Strengthening Communities Fund Nonprofits Capacity Building Program The goal of this program is to build the capacity of our nonprofit partners in order to address the broad economic recovery issues present our community, including helping low-inco
This spending item is part of a $973,584 allocation. See details
Administration for Children and Families 9/19/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $44,804 Trans-NIH Recovery Act Research Support The requested supplement includes funds for the purchase of a critical research instrument (an FPLC system) and stable istopes, and will accelerate the pace of scientific research on the interaction of HIV-1 capsid protein with human cyclophilin A. The pu National Institutes of Health 6/01/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $43,798 Trans-NIH Recovery Act Research Support Translation termination is the final stage of protein synthesis. It includes at least two essential functions, stop codon recognition and polypeptide chain release. In eukaryotic organisms, the class I release factor eRF1 recognizes each of the three term National Institutes of Health 12/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $42,675 Trans-NIH Recovery Act Research Support The B1a (CD5+) B-cells are the primary producers of natural antibodies that are self-reactive and polyreactive but usually non-pathogenic. However, in some circumstances, B1a B-cells contribute substantially to the immunopathogenesis of chronic systemic a National Institutes of Health 6/29/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $42,413 Trans-NIH Recovery Act Research Support This administrative supplement is concerned with the optimization and reduction to practice of an assay for a biomarker, PGP, that appears diagnostic and perhaps prognostic for COPD. Although it is currently possible to measure elevated PGP levels in COP National Institutes of Health 5/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $42,400 ARRA - Health Information Technology Extension Program USA'S CENTER FOR STRATEGIC HEALTH INNOVATION HAS FORMED A CONSORTIUM OF PARTNERS INCLUDING ALABAMA MEDICAID AGENCY, UNIVERSITY OF ALABAMA AT BIRMINGHAM, AUBURN UNIVERSITY AND THE ALABAMA PRIMARY HEALTHCARE ASSOCIATION TO SERVE AS THE ALABAMA REGI... Show more
This spending item is part of a $9,042,318 allocation. See details
Health and Human Services, Department of 4/06/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $40,810 Trans-NIH Recovery Act Research Support The overall objective of the parent grant (HD056030) is to understand how disruption of cilia alters the hedgehog signaling pathway and subsequently results in severe birth defects and disease states. The purpose of this supplement was to request funds t National Institutes of Health 7/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $40,180 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The Specialized Program of Translational Research in Acute Stroke (SPOTRIAS) at the University of California San Diego (UCSD) Stroke Center currently applies the resources of 4 Cores to conduct 3 interrelated clinical
This spending item is part of a $140,237 allocation. See details
National Institutes of Health 9/25/2009
JEFFERSON STATE COMMUNITY COLLEGE $40,148 ARRA - Scholarships for Disadvantaged Students ARRA-SDS funding assists Jefferson State Community College's efforts to increase shortages of primary health care practitioners and other health professionals by providing financial assistance to ensure students from disadvantaged backgrounds will have v... Show more Health Resources and Services Administration 6/14/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $39,335 Trans-NIH Recovery Act Research Support This application is submitted in response to NOT-OD-09-056 for an Administrative Supplement to R01 HD 059140 (Morrow, PI; Schibler, co-PI), G?Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.G? This grant was awarded in January
This spending item is part of a $59,916 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $39,335 Trans-NIH Recovery Act Research Support This project is to support the establishment of a Center of Excellence for conducting Comparative Effectiveness Research for Eliminating Disparaties (CERED). The USF Moffitt CERED will conduct a comparative effectiveness research project regarding inform
This spending item is part of a $1,400,000 allocation. See details
National Institutes of Health 7/31/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $38,907 Trans-NIH Recovery Act Research Support Alexander disease is a rare and typically fatal neurodegenerative disease that results from heterozygous mutations in the gene encoding the type III intermediate filament protein GFAP. The pathological signature of the disorder is the Rosenthal fiber, a c National Institutes of Health 9/24/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $36,369 Trans-NIH Recovery Act Research Support A supplement was requested to hire a research assistant to analyze samples collected through the parent grant. The research assistant hired through supplemental funds will oversee three major tasks: 1) establishing the laboratory and managing daily opera National Institutes of Health 8/09/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $35,000 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) in children is a devastating illness. The prevalence of patients aged 0 ? 19 years with ESRD has grown 32% since 1990 and the mortality rate for children with ESRD receiving dialysis therapy is between 30 and 150 times that o
This spending item is part of a $525,000 allocation. See details
National Institutes of Health 9/27/2009
County of Jefferson $34,230 Trans-NIH Recovery Act Research Support The increasing value of medical imaging has resulted in an exponential rise in its use for patient care. Unfortunately, there has been no effective concomitant rise of means to share and communicate these data, resulting in inadequate patient service, co
This spending item is part of a $1,612,462 allocation. See details
National Institutes of Health 9/28/2009
JEFFERSON STATE COMMUNITY COLLEGE $33,802 ARRA - Scholarships for Disadvantaged Students ARRA-SDS funding assists Jefferson State Community College?s efforts to increase shortages of primary health care practitioners and other health professionals by providing financial assistance to ensure students from disadvantaged backgrounds will have v... Show more Health Resources and Services Administration 9/03/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $33,007 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $31,058 Trans-NIH Recovery Act Research Support University of Alabama at Birmingham (UAB) is one of America's premier research universities, ranking among the top 20 in funding from the NIH and earns more than $610 million per year in contract and grant support from federal agencies. Research enterpri National Institutes of Health 8/05/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $30,739 Trans-NIH Recovery Act Research Support This is a request for supplementary funds to the parent grant DK080981, Stress-Induced Bladder Hyperalgesia: A Potential Mediator, to procure a FluoSTAR microplate reader ($30,000.00; BMG Labtech, Durham, NC.) and a Dell computer ($640.00) and printer ($9 National Institutes of Health 12/08/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $30,000 Trans-NIH Recovery Act Research Support This application responds to broad Challenge Area (05): Comparative Effectiveness Research (CER), and specific Challenge Topic 05-AR-101: Comparative Effectiveness of Biologics in Autoimmune Rheumatic and Skin Diseases, with emphasis on five diseases: rhe
This spending item is part of a $999,370 allocation. See details
National Institutes of Health 9/28/2009
CHILDREN'S HOSPITAL OF ALABAMA, THE $29,380 Trans-NIH Recovery Act Research Support The increasing value of medical imaging has resulted in an exponential rise in its use for patient care. Unfortunately, there has been no effective concomitant rise of means to share and communicate these data, resulting in inadequate patient service, co
This spending item is part of a $1,612,462 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $27,521 Trans-NIH Recovery Act Research Support R01 NS064025; PI Linda Overstreet-Wadiche, PhD; Adult neurogenesis is a mechanism that links experiences with structural plasticity and regeneration of the adult brain. Despite the extensive literature supporting experience-dependent regulation of adult National Institutes of Health 7/20/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $25,371 Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C
This spending item is part of a $750,000 allocation. See details
National Institutes of Health 8/13/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $24,539 Trans-NIH Recovery Act Research Support This administrative supplement request under ARRA is to support summer students in 2009 and in 2010 for the REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction Study, R01HL080477. The parent R01 will end April 30, 2011, and is th National Institutes of Health 5/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $22,465 Trans-NIH Recovery Act Research Support This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/
This spending item is part of a $1,405,307 allocation. See details
National Institutes of Health 8/12/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $18,158 Trans-NIH Recovery Act Research Support The award is a supplement to a NIH-supported project. This fund allows us to provide a research opportunity in the biomedical area for a college student or college graduate. The study will generate novel insights on how Ebolavirus replicates. Ebolavirus i National Institutes of Health 7/14/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $18,134 Trans-NIH Recovery Act Research Support Fibroblasts mediate the abnormal tissue repair characteristic of fibrosis, but their origin in fibrotic lung remains unclear. Many of the fibrogenic characteristics of lung fibroblasts are regulated by expression of Thy-1, an outer membrane leaflet surfac National Institutes of Health 6/05/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $16,936 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for two college studnets, science educators in health-related sceintific research. The major task of this administrative supplemental grant application is to provide basic research training opportunity by h National Institutes of Health 6/04/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $16,936 Trans-NIH Recovery Act Research Support The University of Alabama at Birmingham (UAB) is one of America's premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earning more than $360 million per year in contract and grant support, with mor National Institutes of Health 5/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $16,936 Trans-NIH Recovery Act Research Support This grant provided a summer research experiences for two college students in health-related scientific research. UAB is one of America's premier research universities, ranking among the top 20 in funding from the National Institutes of Health and earnin National Institutes of Health 6/02/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $16,687 Trans-NIH Recovery Act Research Support Summer experience for high school science teacher and undergraduate student considering career in research. Worked on studies funded by primary grant. They participated in whole animal research, didactic lectures related to scientific method, project fo National Institutes of Health 7/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $15,777 Trans-NIH Recovery Act Research Support The challenges of warfarin therapy are significantly greater among patients with chronic kidney disease (CKD) and ESRD compared to that among patients with normal renal function. CKD can significantly reduce non-renal clearance and alter the bioavailabili National Institutes of Health 6/01/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $14,644 Trans-NIH Recovery Act Research Support This grant is exploring the role of cell volume changes associated with the unique biology of malignant gliomas. The overarching hypothesis posits that well orchestrated cell volume changes accompany cell invasion, glioma cell proliferation and programmed National Institutes of Health 7/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $14,644 Trans-NIH Recovery Act Research Support 5R01NS040593-09; P.I. Lucas Pozzo-Miller, PhD; This grant is focused on the immediate actions of the neurotrophin BDNF on membrane currents and intracellular Ca2+ levels in hippocampal neurons. BDNF has recently emerged as a potent modulator of activity National Institutes of Health 7/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $14,644 Trans-NIH Recovery Act Research Support This grant is exploring the role of intracellular Ca2+ in the migration/invasion of normal and malignant glial cells. Specifically we are examining the role of Ca2+-activated K+ channels (KCa), a super-family of ion channels that have the unique ability t National Institutes of Health 7/21/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $13,998 Trans-NIH Recovery Act Research Support This award provides funding for establishment of a consortium with the University of Illinois-Chicago, Texas Children's Hospital, & Baylor College of Medicine to obtain samples necessary to complete Phase II validation of novel biomarker profiles in the b
This spending item is part of a $92,740 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $12,969 Trans-NIH Recovery Act Research Support The funding for this award was used to purchase an electronic component to upgrade a mass spectrometer in the University Mass Spectrometry Center. National Institutes of Health 8/27/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $12,500 Trans-NIH Recovery Act Research Support This project will take advantage of the existing infrastructure of the PHACS Study which began protocol development in 2005 after successfully competing for funding by the NICHD. This is a multicenter, multidisciplinary and collaborative study. The PHACS
This spending item is part of a $1,012,474 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $12,235 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $12,000 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Primary vesicoureteral reflux (VUR) is a common problem, occurring [sic] in 8-50% of children with urinary tract infection (UTI). It has the potential for causing irreparable renal damage, particularly [sic] in younge
This spending item is part of a $267,999 allocation. See details
National Institutes of Health 8/18/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $11,625 Trans-NIH Recovery Act Research Support Data for this study comes from CNICS, which is a multi-center collaborative project to create and maintain the CFAR Network of Integrated Clinical Systems (CNICS), a clinical cohort for longitudinal studies in HIV.The CNICS Network provides anonymized dem
This spending item is part of a $138,211 allocation. See details
National Institutes of Health 9/07/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $10,460 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $10,152 Trans-NIH Recovery Act Research Support Chikungunya virus (CHIKV) is an emerging, mosquito-borne alphavirus and potential biological weapon that has caused debilitating, chronic arthralgia in at least 2 million persons in Asia and Africa since 2005. CHIKV was recently placed on the National In
This spending item is part of a $1,933,570 allocation. See details
National Institutes of Health 7/30/2009
VISTA ENGINEERING, INC. $10,000 Trans-NIH Recovery Act Research Support Temporomandibular Disorders (TMD) usually represent a collection of medical and dental conditions affecting the temporomandibular joint (TMJ) and/or the muscles of mastication, as well as contiguous tissue structures. For some patients with severe TMJ deg National Institutes of Health 6/03/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $9,083 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for 1 college student in health-related scientific research. It supplements 5R01HD058573-02, Using Virtual Reality to Train Children in Pedestrian Safety, a Randomized Controlled Trial research project des National Institutes of Health 5/03/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $9,059 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for 1 college students in health-related scientific research. This award supplements 5R01HD058573-02, Using Virtual Reality to Train Children in Pedestrian Safety, a Randomized Controlled Trial research pr National Institutes of Health 7/15/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $8,473 Trans-NIH Recovery Act Research Support The approved summer student project seeks to investigate the role of TGF-+? in intestinal macrophage differentiation in transgenic mice that lack TGF-+? signaling. We had designed a set of sequential studies to investigate the hypothesis that the absence National Institutes of Health 7/15/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $8,468 Trans-NIH Recovery Act Research Support Administrative supplement to R21 parent grant. The parent study aimed to (1) characterize the longitudinal rate of paramedic endotracheal intubation (ETI) experience accumulation, (2) determine the diseases of patients receiving paramedic ETI and (3) iden National Institutes of Health 6/05/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $8,030 Trans-NIH Recovery Act Research Support This grant provided summer research experiences for two undergraduate college students from UAB and Duke Universities to do health-related leukemia and stem cell research. National Institutes of Health 6/01/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $7,325 Trans-NIH Recovery Act Research Support The B1a (CD5+) B-cells are the primary producers of natural antibodies that are self-reactive and polyreactive but usually non-pathogenic. However, in some circumstances, B1a B-cells contribute substantially to the immunopathogenesis of chronic systemic a National Institutes of Health 5/24/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $1,464 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $0 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to elucidate the mechanisms by which lung tumor exosomes promote an inflammatory response, namely the activation of macrophages, and promote the progression and growth of lung tumors. Our preliminary data iandicate th National Institutes of Health 7/31/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $0 Trans-NIH Recovery Act Research Support This is a proposal for an administrative supplement of $286,500 (direct costs) to my grant U01 AI069569-07 to accelerate the pace of generation of a vaccine product for the proposed phase I clincial studies. By supplementing the funding of this grant to
This spending item is part of a $286,500 allocation. See details
National Institutes of Health 6/14/2010