Recovery Tracker

How Much Stimulus Funding is Going to Your County?

San Diego County, Calif., funds by Health and Human Services, Department of

Listing $414,864,181.97 in stimulus funds from Health and Human Services, Department of for San Diego

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
UNIVERSITY OF CALIFORNIA, SAN DIEGO $13,242,420 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $12,556,085 National Center for Research Resources, Recovery Act Construction Support Funding for in-vivo based research at UCSD has doubled over the past decade while the primary species used (mice) has almost tripled during this same time period. Cleanliness achieved from adequate sanitation and sterilization ... Show more
This spending item is part of a $14,287,680 allocation. See details
National Institutes of Health 3/31/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $11,392,822 Trans-NIH Recovery Act Research Support Our goal is to determine the clinical, cognitive, imaging, genetic, and biochemical biomarker characteristics of the early (pre-dementia) stages of Alzheimer's disease (AD). The project builds on the NIA-funded AD Neuroimaging Initiative (ADNI1) and serve
This spending item is part of a $23,822,294 allocation. See details
National Institutes of Health 9/24/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $11,052,633 Trans-NIH Recovery Act Research Support G?New players in immune function: identification through RNAi and mircor-RNA screensG?: Although all human genes have been identified, the actual functions of most genes are still mysterious. Recently, an experimental technique known as RNAi screening ha
This spending item is part of a $12,579,073 allocation. See details
National Institutes of Health 9/27/2010
CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO, INC. $9,754,515 ARRA Health Center Integrated Services Development Initiative[g1] Add New Service Site: Euclid Family Health Center(EFHC) 950 S Euclid, San Diego, CA 92114-6201. EFHC goals are (1) to increase access to primary care services and (2) decrease health disparities throughout a target population. The EFHC... Show more Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $5,924,730 Recovery Act Comparative Effectiveness Research - AHRQ We will develop a distributed network infrastructure for comparative effectiveness research that provides flexibility to participant sites in the means for data sharing. This flexibility will be implemented by allowing codification of data shar... Show more
This spending item is part of a $8,309,906 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
SAN DIEGO, COUNTY OF $5,366,465 ARRA - Community Services Block Grant The Community Services Block Grant (CSBG) American Recovery and Reinvestment Act (ARRA) funding appropriated $89 million to support the activities provided by 60 California CSBG eligible entities. The CSBG eligible entities are comprised of local governme
This spending item is part of a $89,150,062 allocation. See details
Administration for Children and Families 4/10/2009
SAN DIEGO, COUNTY OF $4,661,632 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $4,429,620 National Center for Research Resources, Recovery Act Construction Support The Salk Institute for Biological Studies focuses on fundamental biomedical discoveries aimed at the improvement of human health. Led by 57 faculty members, the Salk receives ~$58 million annually from the NIH in the form of in... Show more National Institutes of Health 11/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $4,079,399 Trans-NIH Recovery Act Research Support This application is submitted by a group of investigators at 9 sites distributed throughout the U.S. where there are active developmental research programs involving substantial numbers of typically developing children, and neuroimaging investigators with
This spending item is part of a $8,950,690 allocation. See details
National Institutes of Health 9/30/2009
Thunder-Jones Contracting Group, Inc $3,855,686 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $3,622,775 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
SCRIPPS RESEARCH INSTITUTE, THE $3,284,735 Trans-NIH Recovery Act Research Support The majority of human neurological and psychiatric disorders involve impairment in learning and memory. This project will identify all genes in the genome of a model organism that have fundamental roles in the neurobiological processes underlying learning National Institutes of Health 9/30/2010
SCRIPPS RESEARCH INSTITUTE, THE $3,122,468 Trans-NIH Recovery Act Research Support The project will procure, process and analyze knees from 100 humans age 20-90 at autopsy each year. The knees are analyzed macroscopically and by various imaging techniques. Tissues, cells, RNA, DNA and protein are isolated from the knees and distributed
This spending item is part of a $4,245,533 allocation. See details
National Institutes of Health 8/14/2009
SAN DIEGO ASSOCIATION OF GOVERNMENTS $3,078,935 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $3,078,774 Trans-NIH Recovery Act Research Support A critical issue for disaster response is group or collaborative computing in mobile environments. This application describes research to address three critical inter-related problems that inhibit the successful use of information technologies at disaster
This spending item is part of a $3,157,848 allocation. See details
National Institutes of Health 9/17/2009
SAN DIEGO COUNTY OFFICE OF EDUCATION $3,068,306 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
FAMILY HEALTH CENTERS OF SAN DIEGO, INC. $3,000,000 ARRA Health Center Integrated Services Development Initiative[g1] As two of the largest FQHCs in the United States, FHCSD and PMS have strategically partnered to address large challenges for more than two decades. At the start of the AIDS crisis, the CEOs of these FQHCs came together with two others ... Show more Health Resources and Services Administration 6/01/2010
ADVANCED TARGETING SYSTEMS $3,000,000 Trans-NIH Recovery Act Research Support Pain due to cancer is one of the great fears, at times greater than even death, in the progression of the disease. Numerous studies have shown the preponderance of pain in terminal cases. But even worse, many times this pain is refractory to the last stan National Institutes of Health 9/01/2010
LPATH THERAPEUTICS INC. $3,000,000 Trans-NIH Recovery Act Research Support Exudative (or wet) AMD (age-related macular degeneration) is the leading cause of severe vision loss and blindness among older Americans. While Lucentis-? and off-label use of Avastin-??the clear market leaders in wet AMD?improve vision in some patients f National Institutes of Health 7/22/2010
ADVANCED TARGETING SYSTEMS $3,000,000 Pain due to cancer is one of the great fears, at times greater than even death, in the progression of the disease. Numerous studies have shown the preponderance of pain in terminal cases. But even worse, many times this pain is refractory to the last stan National Institutes of Health 9/01/2010
ADVANCED TARGETING SYSTEMS $3,000,000 Trans-NIH Recovery Act Research Support Pain due to cancer is one of the great fears, at times greater than even death, in the progression of the disease. Numerous studies have shown the preponderance of pain in terminal cases. But even worse, many times this pain is refractory to the last stan National Institutes of Health 9/01/2010
SCRIPPS RESEARCH INSTITUTE, THE $2,957,107 Trans-NIH Recovery Act Research Support Tobacco usage remains one of the most prevalent forms of substance abuse and exerts a tremendous cost on the world health and economy. While it is known that nicotine is the major component in tobacco smoke responsible for addiction, we currently have onl National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $2,840,711 Trans-NIH Recovery Act Research Support The 4DB Center's potential impact is on two fronts, the basic research ability to conduct physical sciences experiments on cancer patient samples in a meaningful way and to generate the force and time journey of cancer cells during the metastatic phase. T
This spending item is part of a $3,878,972 allocation. See details
National Institutes of Health 9/29/2009
NEIGHBORHOOD HOUSE ASSOCIATION, THE $2,553,498 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
FAMILY HEALTH CENTERS OF SAN DIEGO, INC. $2,500,000 ARRA Health Center Integrated Services Development Initiative[g1] Family Health Centers of San Diego (FHCSD) will address the communityG??s immediate need for expanded access to affordable healthcare services by relocating and expanding its City Heights Family Health Center (CHFHC). CHFHC is current... Show more Health Resources and Services Administration 6/25/2009
NEIGHBORHOOD HEALTHCARE $2,500,000 ARRA Health Center Integrated Services Development Initiative[g1] The CIP award will provide needed renovation, implement electronic health records, and purchase equipment for Neighborhood Healthcare (NHcare)to meet the needs of the increasing uninsured population. NHcare has provided medical, dental... Show more Health Resources and Services Administration 6/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $2,411,243 Trans-NIH Recovery Act Research Support CYCORE: CYBERINFRASTRUCTURE FOR COMPARATIVE EFFECTIVENESS RESEARCH
This spending item is part of a $3,866,878 allocation. See details
National Institutes of Health 9/30/2009
CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO, INC. $2,366,765 ARRA Health Center Integrated Services Development Initiative[g1] For San Ysidro Health Center(SYHC) -Facility Renovation. The proposed clinic renovation is to re-structure and maximize space by improving patient flow and access. SYHC will expand two clinic areas: 1. Walk-in/Urgent Care Services-by ... Show more Health Resources and Services Administration 6/25/2009
NORTH COUNTY HEALTH PROJECT, INC $2,362,985 ARRA Health Center Integrated Services Development Initiative[g1] North County Health Project, Inc. (NCHS) received funding under the ARRA Capital Improvement Program for 3 projects. The largest project ($2,018,572) was for the selection and purchase of a certified Electronic Health Records (E H R) ... Show more Health Resources and Services Administration 6/25/2009
COMMUNITY CLINICS HEALTH NETWORK $2,294,820 ARRA - Health Information Technology Extension Program Technical assistance services for primary care health providers to support electronic health record adoption. In partnership with the California Primary Care Association (CPCA), the California Medical Association (CMA), and the California Asso... Show more
This spending item is part of a $15,760,570 allocation. See details
Health and Human Services, Department of 2/08/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $2,213,935 Trans-NIH Recovery Act Research Support Primary open angle glaucoma (POAG) is the most common form of glaucoma in the United States and a leading cause of irreversible blindness and visual impairment worldwide, affecting more than 2 million Americans over age 40, and causing blindness in ~100,0 National Institutes of Health 2/01/2010
FAMILY HEALTH CENTERS OF SAN DIEGO, INC. $2,194,615 ARRA Health Center Integrated Services Development Initiative[g1] Family Health Centers of San Diego's (FHCSD) Increased Demand for Services (IDS) grant is funding a number of new positions and service expansions at our network of health centers so that we are able to respond to the increased demand ... Show more Health Resources and Services Administration 3/27/2009
METROPOLITAN AREA ADVISORY COMMITTEE ON ANTI-POVERTY OF SAN DIEGO COUNTY INC $2,177,608 ARRA - Early Head Start MAAC Project was awarded ARRA Early Head Start Expansion funds to provide services to an additional 99 children & pregnant woman. For Early Head Start Expansion including playground, bus, van, madular, and classroom supplies. The purpose of the EHS pro Administration for Children and Families 11/18/2009
VISTA COMMUNITY CLINIC $2,085,505 ARRA Health Center Integrated Services Development Initiative[g1] The CIP ARRA funds have been designated by Vista Community Clinic for the following four projects: 1) Equipment only project -- purchase of equipment necessary to complete the equipping and furnishing of the newly constructed Grapevi... Show more Health Resources and Services Administration 6/25/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $2,061,597 Trans-NIH Recovery Act Research Support The function of the nervous system is dependent on complex interactions between networks of neurons composed of multiple neuron types. Understanding how these networks function both in health and disease is dependent on understanding the precise connectiv
This spending item is part of a $2,829,341 allocation. See details
National Institutes of Health 9/24/2009
FAMILY HEALTH CENTERS OF SAN DIEGO, INC. $1,865,625 ARRA Health Center Integrated Services Development Initiative[g1] This grant will be use to implement Electronic Health Records (WorldVistA) for Family Health Centers of San Diego medical and mental health practices. The grant will be used to equip Family Health Centers of San Diego with the technolo... Show more Health Resources and Services Administration 9/19/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $1,838,410 Trans-NIH Recovery Act Research Support Bipolar disorder (BPD) is a neuropsychiatric condition defined by a lifetime of relapsing & remitting manic & depressive episodes. This mood disorder has been shown to have strong genetic linkage with familial predisposition. A major impediment to proper National Institutes of Health 9/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $1,836,114 Trans-NIH Recovery Act Research Support The ubiquitin system of protein modification permeates every field in biology and is intimately linked to the most prevalent human diseases, including cancer, neurodegeneration, inflammation, and viral infections. With ~30 E2s and an estimated several hun National Institutes of Health 9/29/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $1,779,809 Trans-NIH Recovery Act Research Support Dengue virus (DENV) causes dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), the most prevalent mosquito-borne viral illnesses in humans worldwide. Studies suggest that sub-neutralizing concentrations of DENV-specific antibod National Institutes of Health 9/01/2009
HDR ARCHITECTURE, INC. $1,731,595 National Center for Research Resources, Recovery Act Construction Support Funding for in-vivo based research at UCSD has doubled over the past decade while the primary species used (mice) has almost tripled during this same time period. Cleanliness achieved from adequate sanitation and sterilization ... Show more
This spending item is part of a $14,287,680 allocation. See details
National Institutes of Health 3/31/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,616,361 Trans-NIH Recovery Act Research Support Transcription factors (TF) have a crucial role in controlling gene expression, and exploring their molecular targets, binding partners and mode of regulation is essential to understand any plant biological process. Arabidopsis offers some unique advantage
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,585,466 Trans-NIH Recovery Act Research Support Effective prevention strategies for HIV are critically needed, and an effective HIV vaccine is the best long-range hope to dramatically reduce the rate of new HIV infections. To this goal, our current understanding of the biology and epidemiology of HIV t
This spending item is part of a $2,113,918 allocation. See details
National Institutes of Health 5/03/2010
SCRIPPS RESEARCH INSTITUTE, THE $1,526,440 Trans-NIH Recovery Act Research Support G?New players in immune function: identification through RNAi and mircor-RNA screensG?: Although all human genes have been identified, the actual functions of most genes are still mysterious. Recently, an experimental technique known as RNAi screening ha
This spending item is part of a $12,579,073 allocation. See details
National Institutes of Health 9/27/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,519,725 Trans-NIH Recovery Act Research Support This is an Adminstrative Supplement Award for the recruitment of new faculty in NCI Designated Cancer Center (P30) at the Moores UCSD Cancer Center, Universtiy of California San Diego. The fund is a two-year support to recruit a physician scientist who h National Institutes of Health 9/24/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $1,516,543 Trans-NIH Recovery Act Research Support The impact of antiretroviral therapy represents a major demonstration of the capability and success of modern drug discovery, development, and implementation. Nevertheless, in infected individuals this success lasts only as long as adherence to the regime
This spending item is part of a $1,771,712 allocation. See details
National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,455,686 Trans-NIH Recovery Act Research Support Molecular and Cellular Mechanisms Underlying Function and Dysfunction of Neural Circuits. The overall purpose of this award is to recruit two junior faculty members (principal investigators) to a new Program in Neural Circuits and Behavior. Funds will sup National Institutes of Health 9/15/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,449,022 Trans-NIH Recovery Act Research Support The applicant has been in the forefront of studies of the function of PB1-F2. Studies in cells have shown that PB1-F2 targets the mitochondrial membrane where it interacts with AMT3 and VDAC1 of the permeability transition pore complex causing the release
This spending item is part of a $7,935,507 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,438,166 Recovery Act Comparative Effectiveness Research - AHRQ Comprehensive care models are emerging as the new standard for management of patients with chronic disease. These models typically involve a single source of care, such as a medical home, and coordinate a range of medical and psychosocial service... Show more Agency for Healthcare Research and Quality 9/28/2010
SCRIPPS RESEARCH INSTITUTE, THE $1,437,673 Trans-NIH Recovery Act Research Support We are investigating the regulation of the enzymatic formation 01 reactive oxygen species (ROS) by NAOPH oxidases (Nox). The current goals address two areas; 1) How Rae GTPase binds to and regulates Nox activity; and 2) The regulation of Nox activity by S National Institutes of Health 6/01/2009
WEST TECH CONTRACTING, INC. $1,431,639 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,394,520 ARRA - Prevention and Wellness--State Territories and Pacific Islands At 13.3 percent, California?s adult smoking prevalence ranks second lowest in the nation, yet this percentage represents nearly 3.8 million adult smokers. Current youth (9th to 12th grade) prevalence is 14.6 percent, representing... Show more
This spending item is part of a $2,501,528 allocation. See details
Centers for Disease Control and Prevention 2/06/2010
LA MAESTRA FAMILY CLINIC, INC. $1,374,235 ARRA Health Center Integrated Services Development Initiative[g1] ARRA CIP grant equipment for a new medical facility. The goal was to purchase part of the equipment for this new physical medical facility which is of importance as we did not have sufficient funds for the purchase of this needed equip... Show more Health Resources and Services Administration 6/25/2009
LA MAESTRA FAMILY CLINIC, INC $1,374,225 Equipment for the new physical building under construction to move all medical, dental and mental health services, as well as all enabling services: Pharmacy, Optometry, transportation, community health workers and health education. Will also include some Health Resources and Services Administration 6/25/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $1,343,155 Trans-NIH Recovery Act Research Support Stroke is a major cause of death throughout the world and its prevalence is increasing with increased longevity and obesity-associated vascular disease. There are, however, very few effective therapeutics. During the last few years we have identified a br
This spending item is part of a $1,637,015 allocation. See details
National Institutes of Health 9/07/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,325,206 Trans-NIH Recovery Act Research Support The overall goal of this project is to understand the roles of vascular and innate immune cell PAR signaling in inflammation using mouse genetic models. Proposed experiments on the role of PAR1 signaling in innate immune cells address how thrombin signali National Institutes of Health 9/11/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,311,987 Trans-NIH Recovery Act Research Support The overall objective of the project is to complete preclinical development of a formulated caspase inhibitor for the intraarticular treatment of patients with posttraumatic arthritis and the prevention of chronic osteoarthritis. The first milestone of t National Institutes of Health 9/29/2009
CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO, INC. $1,300,000 ARRA Health Center Integrated Services Development Initiative[g1] To establish a New Access Point(NAP)Clinic in support of a new site and service area originally submitted in response to HRSA-08-077. Health Resources and Services Administration 2/26/2009
FAMILY HEALTH CENTERS OF SAN DIEGO, INC. $1,300,000 ARRA Health Center Integrated Services Development Initiative[g1] Family Health Centers of San Diego received a New Access Point grant from the Health Resources and Services Administration to establish a new community health center in Lemon Grove, CA. By the 3rd year of the Lemon Grove Family Health... Show more Health Resources and Services Administration 2/26/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,285,619 Trans-NIH Recovery Act Research Support This application seeks support for a center of excellence in computational mass spectrometry and a national and international resource in the broad area of proteomics. It proposes to enlarge the current research activities, to branch into previously unexp National Institutes of Health 8/31/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,260,932 Trans-NIH Recovery Act Research Support Our research amis at using chemical synthesis to prepare four classes of anticancer natural products with great potential that have eluded study due to their scarcity in nature and the fact that no solution for their chemical synthesis exists. Practical National Institutes of Health 5/07/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,259,770 Trans-NIH Recovery Act Research Support In this project, we will engineer Morburgvirus glycoprotein GP for high-leve,. homogeneous expression, and crystallizability. Any crystals obtained will be tested for X-ray diffraction, with the ultimate goal of provision of a crystal structure of marburg National Institutes of Health 9/01/2009
SAN DIEGO STATE UNIVERSITY $1,250,869 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $1,247,552 Trans-NIH Recovery Act Research Support Alcoholism (alcohol abuse and dependence) is a common disorder with a peak age of onset in early adulthood and a complex etiology. Twin studies comprised predominantly of participants of European Caucasian ancestry have shown genetic factors contribute 40 National Institutes of Health 9/09/2009
ILLUMINA, INC. $1,228,423 ARRA H1N1 (flu) Large Equipment Request: This requirement will purchase equipment that will support ongoing Influenza projects within the Division of Intramural Research, NIAID (National Institute of Allergy and Infectious Diseases). The deliverables incl National Institutes of Health 9/27/2010
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $1,202,160 Trans-NIH Recovery Act Research Support One of the fundamental unanswered questions of sensory biology is how information provided by individual neurons within the brain is linked into a coherent whole. Individual visually responsive neurons only respond to stimulation over a limited portion of National Institutes of Health 7/17/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $1,169,824 Trans-NIH Recovery Act Research Support The study will provide a significant complement to the parent HCHS/SOL study, to help achieve the goal of examining varied risk and protective factors in Hispanic health and will provide much needed information on the role of SES, sociocultural and psycho
This spending item is part of a $4,710,605 allocation. See details
National Institutes of Health 9/29/2009
COMMUNITY HEALTH SYSTEMS, INC $1,157,760 ARRA Health Center Integrated Services Development Initiative[g1] Alteration/Repair/Renovation of the New Fallbrook Family Health Center. The current facilities are located in 6 separate buildings. This award allows the Fallbrook Family Health Center to provide a single point of access to meet the p... Show more Health Resources and Services Administration 6/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,150,829 Trans-NIH Recovery Act Research Support The major goal of this study is centered on biochemical characterization of molecular mechanisms that regulate thrombin generation and blood clotting pathways with specific aims focused on factor V, HDL and HDL lipids. Once clinical research aim addresse National Institutes of Health 9/15/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,144,741 Trans-NIH Recovery Act Research Support This project seeks to identify Oxytocin and Vasopressin ligands that act via the CNS. It is well documented that such molecules would have potential application in disorders such as the pervasive developmental disorders such as Autism and Asperger's as s National Institutes of Health 5/07/2009
SAN DIEGO, COUNTY OF $1,127,368 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
NEIGHBORHOOD HEALTHCARE $1,111,110 ARRA Health Center Integrated Services Development Initiative[g1] Neighborhood Healthcare Grant Name: ARRA ? Increase Services to Health Centers ARRA Increased Demand for Services (IDS) funding supported the hiring and retention of staff to increase access for underinsured and uninsured to medical ... Show more Health Resources and Services Administration 3/27/2009
SAN DIEGO FAMILY CARE $1,102,250 ARRA Health Center Integrated Services Development Initiative[g1] San Diego Family Care was awarded CIP funds for the purpose of purchasing/implementing a Certified EHR-related system and also for the purpose of purchasing IT Equipment. The funds enabled the conversion of paper medical records to ele... Show more Health Resources and Services Administration 6/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,096,941 Trans-NIH Recovery Act Research Support The proposal brings together the complementary strengths of three labs to develop and test a new set of molecular tools that will globally report on the health of the proteome during aging. These groups form the Proteostasis Aging Sensor Consortium (PASC) National Institutes of Health 9/29/2009
COMMUNITY DEVELOPMENT INSTITUTE HEAD START $1,086,407 ARRA - Head Start This award provides ARRA funds for Head Start and Early Head Start Quality Improvement and Cost of Living Adjustments (COLA) in accordance with FY 2009 Funding guidance ACF-PI-HS-09-06. Head Start promotes the school readiness of low-income children thro Administration for Children and Families 7/11/2009
NORTH COUNTY HEALTH PROJECT, INC $1,086,331 ARRA Health Center Integrated Services Development Initiative[g1] The increased demand for services funds awarded to North County Health Project, Inc, NCHS are part of the ARRA funding to increase access to health care for those in need. These funds enable NCHS to provide services using the federal ... Show more Health Resources and Services Administration 3/27/2009
CENTRO DE SALUD DE LA COMUNIDAD DE SAN YSIDRO, INC. $1,060,645 ARRA Health Center Integrated Services Development Initiative[g1] To support approved application for funds to support Increased Demand for Services. The American Recovery and Reinvestment Act(ARRA) of 2009 included funds for increased services at existing sites, and for spikes in demand to serve uni... Show more Health Resources and Services Administration 3/27/2009
VISTA COMMUNITY CLINIC $1,059,758 ARRA Health Center Integrated Services Development Initiative[g1] The goal of ARRA IDS fund usage is to expand access for our target population through a number of actions, including 1) expansion of clinic hours at existing sites where space is available (medical and dental), 2) expansion of pharmacy... Show more Health Resources and Services Administration 3/27/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $1,050,892 Trans-NIH Recovery Act Research Support The principles of immune system function are derivable from a consideration of its evolutionary origins. The rate of germline evolution of pathogens is vastly more rapid than that of their vertebrate hosts. The solution used by evolution was to couple a s National Institutes of Health 7/16/2009
SCRIPPS HEALTH $1,015,363 Trans-NIH Recovery Act Research Support Circulating endothelial cells (CECs) have been shown to be readily detectable in patients with acute coronary syndromes and appear to be remarkably predictive of an impending arterial catastrophe (heart attack or stroke). Even though these cells were disc
This spending item is part of a $1,991,600 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,011,113 Trans-NIH Recovery Act Research Support This application requests funds to purchase current-generation instrumentation for the performance of state-of- the-art peptide amide hydrogen-deuterium exchange mass spectrometry (DXMS), to replace the obsolete instrumentation presently used in the UCSD National Institutes of Health 4/15/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $1,000,000 Trans-NIH Recovery Act Research Support This project addresses how to develop cell-based therapies for cardiovascular, lung and blood diseases. The specific aims are 1) Assess long term persistence characteristics of Pim-1 engineered stem cells in promotion of myocardial repair and regeneration National Institutes of Health 9/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $1,000,000 Trans-NIH Recovery Act Research Support The overall purpose of this project is to identify defined techniques that facilitate the efficient generation of physiologically relevant neurons and myelinating Schwann cells from human skin precursor (SKP) cells. High throughput, cell based screens of National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $1,000,000 Trans-NIH Recovery Act Research Support Niemann Pick Type C (NPC1) is a rare but lethal pediatric dementia caused by a mutation in NPC1, a housekeeping protein residing in the late endosomal compartment with a putative role in cholesterol transport. The result is a severe lipidosis characterize National Institutes of Health 4/19/2010
SCRIPPS RESEARCH INSTITUTE, THE $999,998 Trans-NIH Recovery Act Research Support Multimeric, polyspecific protein therapeutics are difficult to design and produce. The ability to link binding, effector, and imaging components together in a single molecule would be a significant advantage. We propose to develop unnatural amino acid-oli National Institutes of Health 9/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $999,891 Trans-NIH Recovery Act Research Support The Committee on Adolescent Health Care Services, the National Research Council, and the Institute of Medicine have identified adolescents with chronic disease as one of the ?most vulnerable? groups of adolescents. Studies to date demonstrate poor mental National Institutes of Health 9/24/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $999,203 Trans-NIH Recovery Act Research Support The study will explore the mechanisms within social networks, including social learning variables (including the presence of models of behavior, social support, self efficacy to control drinking, and others), acculturation, and ecological variables and th National Institutes of Health 9/22/2009
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD $998,118 Trans-NIH Recovery Act Research Support This application addresses two Broad Challenge areas (15) Translational Science, including specific Challenge Topics 15-NS-104 (Early-stage therapy development) and 15-NS-103 (Demonstration of 'proof-of-concept') and Broad Challenge area (08) Genomics, sp National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $996,973 Trans-NIH Recovery Act Research Support Psychostimulants such as methylphenidate and amphetamine have become drugs of choice for the treatment of attention deficit hyperactivity disorder (ADHD). Along with falling prices for recreational stimulants like powder cocaine, stimulants are increasing National Institutes of Health 7/16/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $990,017 Trans-NIH Recovery Act Research Support The purpose of this project is to develop and test brief communications of nutrition facts and alcohol contents that a)individuals can effectively use to monitor their consumption, b)can motivate them to drink moderately, and c)could be required within ba National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $985,000 Trans-NIH Recovery Act Research Support PURPOSE: Enhancement of the capabilities of the NURSA to generate and disseminate nuclear receptor and coregulator datasets and methodologies of a more translational character. ABSTRACT: Define the temporal and spatial physiology of Nuclear Receptors
This spending item is part of a $3,184,099 allocation. See details
National Institutes of Health 9/21/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $982,189 Trans-NIH Recovery Act Research Support Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a comprehensive, integrated public health approach to identify and deliver a spectrum of early detection and treatment services for substance use in general medical care settings. The eff National Institutes of Health 9/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $976,237 Trans-NIH Recovery Act Research Support Circulating endothelial cells (CECs) have been shown to be readily detectable in patients with acute coronary syndromes and appear to be remarkably predictive of an impending arterial catastrophe (heart attack or stroke). Even though these cells were disc
This spending item is part of a $1,991,600 allocation. See details
National Institutes of Health 9/24/2009
SCRIPPS RESEARCH INSTITUTE, THE $972,665 Trans-NIH Recovery Act Research Support A new generation of highly selective, protease-specific anticoagulant drugs is entering clinical applications, but we have an incomplete understanding of how these drugs attenuate inflammatory processes in cardiovascular diseases, obesity, autoimmune diso National Institutes of Health 9/21/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $962,011 Trans-NIH Recovery Act Research Support Exposure to trauma, especially when it manifests as Post-Traumatic Stress Disorder, results in numerous negative consequences for patients, families, and society. Some of the most frequent, disturbing, and treatment resistant symptoms of PTSD are nightmar National Institutes of Health 9/23/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $955,000 Trans-NIH Recovery Act Research Support Our overall goal is to create a 3-dimensional tissue culture model amenable to high throughput screening (HTS), and perform a screen on large libraries of chemical agents. We initially carried out proof-of-concept screens with characterized and FDA-approv National Institutes of Health 9/23/2009
BURNHAM INSTITUTE FOR MEDICAL RESEARCH $955,000 Trans-NIH Recovery Act Research Support Specific Aim 1: Determination of functional structure of KS-GAG for corneal ECM organization. We created mutant mice lacking a carbohydrate sulfotransferase that is required for KS sulfation and found that the mutant mice show thinner stromal region and National Institutes of Health 6/05/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $955,000 Trans-NIH Recovery Act Research Support The goal of this grant it to maintain and extend the Fold and Function Assignment System (FFAS) server, which was started in 2000 and pioneered protein profileG??profile algorithms, applying them to protein structure and function prediction. Since then, t National Institutes of Health 9/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $955,000 Trans-NIH Recovery Act Research Support Specific Aim 1: Determination of functional structure of KS-GAG for corneal ECM organization. We created mutant mice lacking a carbohydrate sulfotransferase that is required for KS sulfation and found that the mutant mice show thinner stromal region and National Institutes of Health 6/05/2009
SCRIPPS RESEARCH INSTITUTE, THE $952,010 Trans-NIH Recovery Act Research Support Our major purpose for this project is to identify novel biomarkers of risk for VTE among approximately 3,500 plasma metabolites detected by mass spectrometry based analysis. Work began on this project September 30, 2009 and the expected outcome is to acco National Institutes of Health 9/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support This project applies proteomic methodology to analyze peripheral blood samples from patients with hemolytic anemia. Our focus is on evaluation of younger individuals, or those with a family history of anemia, in order to identify novel genetic causes of c National Institutes of Health 9/17/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support The purpose of this research is to define the structural basis for substrate and inhibitor specificities of lentivirus PRs through comparative studies of FIV and HIV PRs. ARRA funding has allowed the continuation of these studies to prepare and test chime National Institutes of Health 6/04/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support The arenaviruses cause devastating viral hemorrhagic fever (VHF) diseases of humans with high fatality rates. Because there is negligible or at best limited antiviral treatment available for these diseases, especially the Old World Lassa fever virus (LFV) National Institutes of Health 5/14/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support This project will explore the activation of human endogenous retroviruses (HERVI to induce immunity to HIV-1 and prevent or ameliorate infection. Small molecules capable of activating HERV expression will be identified, and their ability to stimulate immu National Institutes of Health 8/13/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support The overall goal of the proposal is to determine the mechanisms responsible for the super agonist activity of cytokine/anti-cytokine mAb complexes. The biological activity of many administered cytokines can be greatly boosted by first binding the cytokine National Institutes of Health 5/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support This project is to define the defect in T cell positive selection Themis (previously known as MG143) knockout mice in terms of signaling pathways that are affected, the interactions with other members of the TCR-signaling cascade, and changes in gene expr National Institutes of Health 5/14/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support The long term goal of these studies is to understand how B lymphocytes capable of making antibodies to self tissue are normally prevented from doing so. One form of regulation is receptor editing, in which such cells are reprogrammed to express non autore National Institutes of Health 5/07/2009
SCRIPPS RESEARCH INSTITUTE, THE $949,500 Trans-NIH Recovery Act Research Support We are creating stem cells from human skin cells (we call these stem cellsinduced pluripotential stem cells or iPSCs). Thus, we are able to make stem cells for individual people. These iPSCs have the potential to become any cell in the body. We are abl
This spending item is part of a $2,696,700 allocation. See details
National Institutes of Health 9/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $948,797 Trans-NIH Recovery Act Research Support Dystroglycan is a widely expressed transmembrane glycoprotein that acts as a high- affinity receptor for both extracellular matrix proteins containing laminin-G domains and certain arenaviruses. Secondary dystroglycanopathies encompass a collection of mus
This spending item is part of a $2,536,301 allocation. See details
National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $941,471 Trans-NIH Recovery Act Research Support Neuroinflammation in the central nervous system (CNS) is an important aspect of CNS injury, disease and neurodegeneratlon. The CNS production of proinflammatory cytokines and other neuroimmune molecules is thought to playa role in cognitive, behavior and National Institutes of Health 6/08/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $941,330 Trans-NIH Recovery Act Research Support Methamphetamine (METH) use is of major public health concern given its prevalence among individuals who are HIV infected and its association with HIV transmission risk behaviors, particularly high-risk sexual behavior. METH use strongly alters brain dopa
This spending item is part of a $1,067,183 allocation. See details
National Institutes of Health 8/14/2009
CAMPO BAND OF MISSIONS INDIANS $934,534 ARRA - IHS Tribal Agreements OLD CAMPO URANIUM TREATMENT Indian Health Service 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $927,000 Trans-NIH Recovery Act Research Support Bicarbonate is a vital component of secretions from exocrine glands such as salivary glands, the pancreas, the duodenum, reproductive organs, sweat glands and the airways. It plays a critical role in numerous physiological functions such as digestion, and National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $924,872 Trans-NIH Recovery Act Research Support This grant mechanism is designed to support the hiring of a newly-recruited faculty member and to develop research projects within the context of Biomedical Core Centers. The award is designed to enhance innovative programs of excellence by providing sci National Institutes of Health 9/29/2009
SCRIPPS RESEARCH INSTITUTE, THE $919,998 Trans-NIH Recovery Act Research Support We will perform deep sequencing of small regulatory RNAs expressed in the lymphoma biopsies from 250 patients with diffuse large Bcell lymphoma (DlBCl) and in lymph node biopsies from SO healthy donors, aiming to identify small regulatory RNAs with diagon
This spending item is part of a $999,998 allocation. See details
National Institutes of Health 9/29/2009
SCRIPPS RESEARCH INSTITUTE, THE $915,338 Trans-NIH Recovery Act Research Support Funding was provided to support the development of Mutagenetix, a database of mutations induced by ENU. Both web programming and illustration are funded. Deliverables include the illustration of molecular pathways and the development of Wiki-like histor National Institutes of Health 7/26/2010
SCRIPPS RESEARCH INSTITUTE, THE $903,087 Trans-NIH Recovery Act Research Support The development of a safe and effective topical microbicide to prevent the sexual transmission of HIV could playa major role in worldwide reduction of the over 14,000 new HIV infections per day, and potentially save millions of lives. The goal of this pro National Institutes of Health 7/17/2009
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES, INC. $900,000 Trans-NIH Recovery Act Research Support Some viruses are able to persist in a latent or inactive form in normal healthy individuals, but can reactivate causing a range of diseases, including cancer, in immunocompromised individuals such as AIDS patients or transplant recipients, who lack effect National Institutes of Health 6/04/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $897,696 Trans-NIH Recovery Act Research Support Enzymes of the ubiquitin proteasome system (UPS) and their substrates are increasingly implicated in fundamental cellular processes, including cell proliferation, differentiation, transcriptional regulation, and stress response, amongst many others. With National Institutes of Health 9/08/2009
SCRIPPS RESEARCH INSTITUTE, THE $888,977 Trans-NIH Recovery Act Research Support The goal of this project is to disseminate the Appion Processing Pipeline to the scientific research community. Appion is a software infrastructure that enables and streamlines the complex set of tasks that are required for reconstructing a 3D density map National Institutes of Health 8/24/2009
SCRIPPS RESEARCH INSTITUTE, THE $888,678 Trans-NIH Recovery Act Research Support This project will characterize and develop the ability to transcriptionally modulate HIV-l latency. We have recently discovered that antisense non-coding RNAs can regulate gene transcription and evidence suggests that HIV-l also utilizes this mechanism to National Institutes of Health 9/23/2009
BORREGO COMMUNITY HEALTH FOUNDATION $886,195 ARRA Health Center Integrated Services Development Initiative[g1] ARRA Funding for Four Capital Improvement Projects - 1 - A/R/R - Borrego Medical Foundation Renovation Project. Renovate the flooring at our Borrego Springs clinic. 2 - Certified EHR-Related purchase - EMR system wide project. Purc... Show more Health Resources and Services Administration 6/25/2009
SAN DIEGO, COUNTY OF $879,689 ARRA - Prevention and Wellness--Communities Putting Prevention to Work The four evaluation projects that will be implemented under this project for enhanced evaluation are: 1.) Implementation of a sustainable community-wide BMI surveillance system through linkage of health care providersG?? EHRs to ... Show more
This spending item is part of a $1,768,581 allocation. See details
Centers for Disease Control and Prevention 9/28/2010
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $876,577 Trans-NIH Recovery Act Research Support Statement of the Challenge Area and the specific Challenge Topic: The broad Challenge Area (04) Clinical Research and the specific Challenge Topic (AA-101) Medication Development for Hepatic Fibrosis will be addressed with our project entitled 'C/EBP beta National Institutes of Health 9/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $872,500 Trans-NIH Recovery Act Research Support Control of Lymphocyte Homeostasis by Foxo Transcription Factors: Hematopoietic cells constantly turn over. Their rates of division and death determine the steady-state number of cells and size of lymphoid organs. In particular, T lymphocytes are held in a National Institutes of Health 5/11/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $870,252 Trans-NIH Recovery Act Research Support The aim of this proposal is to establish zebrafish (Danio rerio) models suitable for in vivo studies of certain processes of atherogenesis. It is widely accepted that hypercholesterolemia leads to lipid accumulation in arteries, which in turn induces vasc National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $869,840 Trans-NIH Recovery Act Research Support This application requests funds for purchase of a two-photon microscopy system with imaging and uncaging capabilities that will constitute a shared facility in the Departments of Neurosciences and Radiology at the University of California, San Diego. Two- National Institutes of Health 5/27/2010
SCRIPPS RESEARCH INSTITUTE, THE $867,370 Trans-NIH Recovery Act Research Support The funds are provided to assist in the development of Mutagenetix, a web site for the display, documentation, and in-house organization of work related to ENU mutagenesis in the mouse. This site has so far been designed without specific financial assista National Institutes of Health 7/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $856,378 Trans-NIH Recovery Act Research Support Project Title: Analysis of Neural Circuits using a Genetically-encoded Silencer. Two postdoctoral students and one research technician will direct their effort to generate the constructs requited to generate these mice and to carry out analysis. The mice National Institutes of Health 9/22/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $854,874 Trans-NIH Recovery Act Research Support The overall goals of this project are to investigate the role(s) of the NG2 proteoglycan in mammary tumor vascularization and progression. For this purpose we will utilize the MMTV-PyMT transgenic mouse model of breast cancer. Preliminary experiments have National Institutes of Health 7/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $854,550 Trans-NIH Recovery Act Research Support Transcriptional dysregulation has emerged as a central pathogenic mechanism in Huntington's disease (HO), which is associated with neuropathological changes predominantly in the striatum. Accordingly, mRNAs of genes showing enriched expression in the stri National Institutes of Health 7/27/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $852,500 Trans-NIH Recovery Act Research Support Emerging and established viral diseases take an enormous toll on human health. Current treatment approaches are unlikely to halt epidemic spread of many viruses, notably HIV-1, due to prohibitive costs of treatment (i.e. access), compliance issues, rapid National Institutes of Health 9/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $849,950 Trans-NIH Recovery Act Research Support The purpose of the project is to understand the role of Cks proteins in the etiology of cancer. Cks proteins are overexpressed in a broad spectrum of human cancers, yet the reason for this is not known. We are therefore investigating the cellular phenotyp National Institutes of Health 5/21/2009
SCRIPPS HEALTH $847,703 Trans-NIH Recovery Act Research Support This application is submitted by a group of investigators at 9 sites distributed throughout the U.S. where there are active developmental research programs involving substantial numbers of typically developing children, and neuroimaging investigators with
This spending item is part of a $8,950,690 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $844,040 ARRA - Preventive Medicine Residency Program The University of California, San Diego (UCSD) and San Diego State University (SDSU) General Preventive Medicine Residency (GPMR) proposes this three-year project ?Preventive Medicine Residency Training.? This residency program has been training physicia... Show more Health Resources and Services Administration 7/01/2010
D. A. WHITACRE CONSTRUCTION, INC. $843,213 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SCRIPPS RESEARCH INSTITUTE, THE $833,029 Trans-NIH Recovery Act Research Support Recent studies indicate that neuroimmune factors are important signaling molecules in the brain and contribute to both normal brain function and cognitive dysfunction associated with a variety of disorders including alcoholism. Our knowledge about the rol National Institutes of Health 9/22/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $830,082 Trans-NIH Recovery Act Research Support This grant will extend our studies on the role of ATF2, a transcription factor and DNA damage response protein, in melanoma development and progression. Our preliminary results point to the function of ATF2 as an oncogene in malignant melanoma. We will ex National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $819,284 Trans-NIH Recovery Act Research Support The NHLBI portfolio of genetic association studies does not currently include a large, well characterized study of South Asians, even though the burden of coronary heart disease (CHD) among South Asians is high and rapidly increasing. We propose that the
This spending item is part of a $7,967,526 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $817,406 Trans-NIH Recovery Act Research Support DESCRIPTION: The National Center for Microscopy and Imaging Research (NCMIR) was established to develop computer aided advanced microscopy for acquisition of structural and functional data in the dimensional range of 1 nm3 to 100 um3. With novel specimen National Institutes of Health 8/13/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $804,296 Trans-NIH Recovery Act Research Support RNA interference (RNAi) is a widespread gene-silencing phenomenon initiated by a double-stranded RNA that is converted into small interfering RNAs (siRNAs). Although the detailed mechanism whereby siRNA silences its target gene expression is not understo
This spending item is part of a $1,034,246 allocation. See details
National Institutes of Health 8/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $800,968 Trans-NIH Recovery Act Research Support Since its introduction over a decade ago, functional magnetic resonance imaging (fMRI) has revolutionized studies of the working human brain. While most fMRI studies measure the blood oxygenation level dependent (BOLD) response to a functional task, there National Institutes of Health 8/17/2009
SCRIPPS RESEARCH INSTITUTE, THE $788,086 Trans-NIH Recovery Act Research Support The overall goal of this grant is to investigate the mechanism of oncogene-induced senescence, an important tumor suppressive cellular response that is disrupted during human cancer development. Our study will focus on a potential tumor suppressor protein National Institutes of Health 5/18/2009
VACCINE RESEARCH INSTITUTE OF SAN DIEGO $780,538 Trans-NIH Recovery Act Research Support Research Grant entitled 'Salmonella Genes Associated with Colonization of Specific Hosts'. The purpose of this research is to identify salmonella genes responsible for the colonization of specific host species.
This spending item is part of a $927,762 allocation. See details
National Institutes of Health 5/14/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $775,855 Trans-NIH Recovery Act Research Support Calcification of the medial layer of arteries is common in patients with chronic kidney disease (CKD) and correlates with cardiovascular events and death. Research in our laboratories has demonstrated that vascular calcification is normally inhibited by e
This spending item is part of a $977,102 allocation. See details
National Institutes of Health 9/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $775,080 Trans-NIH Recovery Act Research Support Malaria causes 1-2 million deaths worldwide each year. Resistance to chloroquine, the major antimalarial drug, has emerged in all malaria subtypes and resistant strains now constitute the majority of new infections. A major cause of chloroquine resistan
This spending item is part of a $1,023,775 allocation. See details
National Institutes of Health 6/21/2010
SCRIPPS RESEARCH INSTITUTE, THE $772,436 Trans-NIH Recovery Act Research Support Of two vaccine candidates tested in rats at the Scripps-based Koob lab one was found to be superior and advanced to the rat self administration studies. This vaccine evoked anti-cocaine titers of about 106 and in a parallel study using locomotor behavior
This spending item is part of a $3,840,375 allocation. See details
National Institutes of Health 9/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $769,386 Trans-NIH Recovery Act Research Support This project will characterize the role of the ubiquitin ligase RNF5 in ER stress response in breast cancer and melanoma tumors, where its expression is elevated. Our preliminary results established a novel link between RNF5, ER stress and key phenotypes National Institutes of Health 7/16/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $766,750 Trans-NIH Recovery Act Research Support PURPOSE: Enhancement of the capabilities of the NURSA to generate and disseminate nuclear receptor and coregulator datasets and methodologies of a more translational character. ABSTRACT: Define the temporal and spatial physiology of Nuclear Receptors
This spending item is part of a $3,184,099 allocation. See details
National Institutes of Health 9/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $760,703 Trans-NIH Recovery Act Research Support The vaccine-induced immune responses that, alone or in combination, will provide optimal protection for a large population of individuals against infection by HIV are still unknown. Nevertheless, many regard the induction of broadly neutralizing antibodie National Institutes of Health 9/30/2010
SCRIPPS RESEARCH INSTITUTE, THE $759,647 Trans-NIH Recovery Act Research Support The diversity of all living organisms is encoded within their DNA, where it is stably maintained through DNA replication, and then retrieved through transcription into RNA and translation into proteins. Thus. the di....ersity of life is limited by the fou National Institutes of Health 7/17/2009
SCRIPPS RESEARCH INSTITUTE, THE $759,600 Trans-NIH Recovery Act Research Support The overall purpose of the award is to conduct a lentiviral shRNA screen in human T cells and identify novel genes that are required for T cell receptor signaling and T cell activation. In year 1, we will conduct the full-scale 15,000 shRNA screen. We hav National Institutes of Health 9/08/2009
SCRIPPS RESEARCH INSTITUTE, THE $759,600 Trans-NIH Recovery Act Research Support The long-term scientific purpose the study is to develop risk-markers for individual susceptibility to alcoholism using brainwave measures. The proposal is derived from the PI's previous event-related brain potential (ERP) studies of familial alcoholism a National Institutes of Health 5/22/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $755,600 Trans-NIH Recovery Act Research Support 4-1BB (CD137), a member of the TNFR superfamily, strongly influences immune cell function in many inflammatory situations. 4-1BB was originally described as a costimulatory molecule and binding to its known ligand, 4-1BBL, a member of the TNF family, is t National Institutes of Health 5/15/2009
ILLUMINA, INC. $752,450 Genetic Analysis Equipment National Institutes of Health 9/24/2010
SCRIPPS RESEARCH INSTITUTE, THE $751,120 Trans-NIH Recovery Act Research Support The overall goal of this project is to characterize antigen loading and presentation by MHC and MHC-lik.e molecules primarily through three-dimensional structure determination using x-ray crystallography. The innate and adaptive immune systems playa funda National Institutes of Health 5/21/2009
Diego Raymond-San Inc $744,475 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SCRIPPS RESEARCH INSTITUTE, THE $744,332 Trans-NIH Recovery Act Research Support The new scientific project described in this administrative supplement application is designed to advance in a complementary fashion the primary objectives of our original U19 award -the discovery and validation of biomarkers for kidney transplantation an National Institutes of Health 9/11/2009
SCRIPPS RESEARCH INSTITUTE, THE $744,332 Trans-NIH Recovery Act Research Support The new scientific project described in this administrative supplement application is designed to advance in a complementary fashion the primary objectives of our original U19 award -the discovery and validation of biomarkers for kidney transplantation an National Institutes of Health 9/07/2010
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $738,240 Trans-NIH Recovery Act Research Support The proposed studies are focused upon identifying and inhibiting the pathogenic process by which a high-fat or western-style, diet evokes Type 2 diabetes, using the mouse model of this common mammalian syndrome. Preliminary work completed supports the hyp
This spending item is part of a $859,500 allocation. See details
National Institutes of Health 7/21/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $719,340 Trans-NIH Recovery Act Research Support Immune tolerance in the therapy of rheumatoid arthritis: These studies seek to unravel the immunological mechanisms which lead to the observed immune deviation and which ultimately determine response to the tolerization treatment with dnaJP1. The hypot National Institutes of Health 6/07/2010
SCRIPPS RESEARCH INSTITUTE, THE $696,125 Trans-NIH Recovery Act Research Support The long-term goal of this project is to generate a detailed understanding of viral meningitis in realtime. Knowledge derived from these studies are expected to foster the development of novel interventions to treat this potentially fatal disorder for whi
This spending item is part of a $941,375 allocation. See details
National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $693,885 Trans-NIH Recovery Act Research Support Children with Autism Spectrum Disorders (ASD) are impaired in their ability to produce and perceive dynamic facial expressions (Adolphs, Sears, and Piven, 2001). Advanced computer vision technologies can now be leveraged in the investigation of issues suc
This spending item is part of a $991,790 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $690,000 Trans-NIH Recovery Act Research Support The Pediatric HIV AIDS Cohort Study addresses two critical research questions: (1) the consequences of fetal and infant exposure to antiretroviral therapy (ART) when used to prevent mother-to-child transmission of HIV-1, and (2) the clinical course of per
This spending item is part of a $1,089,382 allocation. See details
National Institutes of Health 9/01/2010
SAN DIEGO COMMUNITY COLLEGE DISTRICT $689,293 ARRA - Health Information Technology Professionals in Health Care The Western Regional Consortium to Educate Information Technology Professionals is a consortium of 14 community colleges from Arizona, Nevada, California, and Hawaii whose purpose is to implement curricula designed by partnering univer... Show more
This spending item is part of a $10,867,915 allocation. See details
Health and Human Services, Department of 4/02/2010
SCRIPPS RESEARCH INSTITUTE, THE $676,527 Trans-NIH Recovery Act Research Support Transplantation is the ideal therapy for end stage heart and end stage kidney failure, but allograft survival and function remain suboptimal. This CTOT renewal application will build upon the findings resulting from the previous 4 years of studying biomar
This spending item is part of a $9,955,156 allocation. See details
National Institutes of Health 9/13/2010
SAN DIEGO, COUNTY OF $671,500 ARRA - Immunization ARRA-317 Immunization and Vaccines for Children Grants. This award will support efforts to plan, develop, and maintain a public health infrastructure for low income children and adults vaccinated against vaccine-preventable diseases.
This spending item is part of a $10,069,863 allocation. See details
Centers for Disease Control and Prevention 9/15/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $668,500 Trans-NIH Recovery Act Research Support Heparan sulfate plays essential roles in development of various tissues. To understand how heparan sulfate functions during skeletal development is of a great clinical importance. Hereditary multiple exostoses (HME) is one of the most common skeletal dysp National Institutes of Health 9/30/2009
METROPOLITAN AREA ADVISORY COMMITTEE ON ANTI-POVERTY OF SAN DIEGO COUNTY INC $663,574 ARRA - Head Start MAAC Project Head Start/ Early Head Start serves over 2,095 children in Full Day, Part Day, Home Base and Combination Option services in the cities of Carlsbad, Escondido, Fallbrook, Oceanside, Pauma, San Marcos, Valley Center and Vista all located in San Administration for Children and Families 6/30/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $643,173 Trans-NIH Recovery Act Research Support The sansalvamide A (San A) scaffold is a promising structure for the development of novel cancer therapeutics. We have used the San A scaffold to produce 7 compounds that are cytotoxic to pancreatic and colon cancer cell lines at nanomolar concentrations. National Institutes of Health 5/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $641,174 Trans-NIH Recovery Act Research Support The long-term goal of this study is to understand the biological function of protein modification by the ubiquitin like protein ISG15. In recent years our knowledge of protein ubiquitination (ubiquitylation) has expanded rapidly and as a consequence prote National Institutes of Health 6/05/2009
SCRIPPS RESEARCH INSTITUTE, THE $635,455 Trans-NIH Recovery Act Research Support The purpose of this award (of a Revision Application) was to begin fulfilling a need of the NIAAA-funded INIA West consortium to use electrophysiological methods to study the function of gene products suggested by the molecular components (particularly th National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $625,000 Trans-NIH Recovery Act Research Support 1. Accelerating progress on the parent grant, 'Effects of insulin-dependent diabetes resistance alleles on COB tolerance in NOD', by increasing the size of our mouse colonies held at Taconic and at Scripps so that more experiments can be performed in a sh National Institutes of Health 8/01/2009
MOLSOFT L.L.C. $620,544 Trans-NIH Recovery Act Research Support The real-time chemistry of life occurs at the interfaces of proteins and small chemicals present in the cellular environment. For the first time in history, sufficient information on the human proteome and its interacting chemogenome has accumulated in th
This spending item is part of a $2,093,862 allocation. See details
National Institutes of Health 7/16/2010
SCRIPPS RESEARCH INSTITUTE, THE $620,126 Trans-NIH Recovery Act Research Support Our study seeks to develop efficacious new therapeutic agents for the treatment of cancer. We hypothesize that through the combination of chemistry and an immune effector we can prepare a versatile and effective new class of immunotherapeutics, chemically National Institutes of Health 7/17/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $618,656 Trans-NIH Recovery Act Research Support The prevalence of autism spectrum disorders (ASD) is now estimated to be 1 in 150, making it a major burden to society. It has been clearly determined that genes play a major role in the etiology of autism, but previous genetic studies
This spending item is part of a $1,319,038 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $618,047 Trans-NIH Recovery Act Research Support COMPARATIVE EFFECTIVENESS AND OUTCOMES IMPROVEMENT (CEOI) CENTER Despite numerous initiatives over the past three decades to improve healthcare quality and outcomes in the United States, progress remains slow; this is particularly true for chronic diseas
This spending item is part of a $3,855,398 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $618,000 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application is a revised proposal to assess aspects of adrenergic receptor and P2Y purinergic receptor signaling. Our recent, preliminary data for this application include the identification and cloning of five di National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $618,000 Trans-NIH Recovery Act Research Support Program Director/Principal Investigator (Last, First, Middle): Kuhn, Richard J. 2 P01 AI055672-06A1 ABSTRACT The current understanding of alphavirus and flavivirus life cycles at the molecular level is incomplete because we lack a structural foundation fo
This spending item is part of a $3,946,282 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $611,100 Trans-NIH Recovery Act Research Support Angiogenesis, the growth of new blood vessels, promotes tumor growth and metastasis. During the previous grant cycle, we found that the fibronectin receptor integrin a4_1 promotes tumor angiogenesis by distinct endothelial cell- and myeloid cell-mediated National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $595,278 Trans-NIH Recovery Act Research Support The overall purpose of the research project is to develop, using click chemistry approaches, novel antibiotics with improved activity against the major periodontal pathogens, bacteria that cause serious gum disease and tooth loss. Timely and cost-effectiv
This spending item is part of a $961,612 allocation. See details
National Institutes of Health 9/17/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $590,550 Trans-NIH Recovery Act Research Support Sign language provides a means to understand the sensory-motor influences on the neural organization of language. The goals of the present proposal are to uncover the neural basis of sign language using modern lesion-deficit mapping. This will not only an
This spending item is part of a $671,613 allocation. See details
National Institutes of Health 8/14/2009
SCRIPPS RESEARCH INSTITUTE, THE $590,000 Trans-NIH Recovery Act Research Support Motions that contribute to biomolecular recognition occur on all timescales, but in contrast to relatively slow dynamics, which may be characterized by a variety of well developed techniques, there are no techniques thatmay be used to characterizing relat
This spending item is part of a $948,598 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $578,486 Recovery Act Comparative Effectiveness Research - AHRQ The G?Variations in Care: Comparing Heart Failure Care Transition Intervention EffectsG? is a comparative effectiveness project that examines approaches to improve variation in resource use and mortality among the five University of California Me... Show more
This spending item is part of a $9,898,332 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
SCRIPPS RESEARCH INSTITUTE, THE $578,244 Trans-NIH Recovery Act Research Support Chromosomal translocations are highly associated with cancer development. Both Nbs1 (Nijmegen breakage syndrome) and Mrell (ataxia-telangiectasia-like disorder) deficient patients exhibit increased levels of chromosomal translocations and higher risk of d National Institutes of Health 9/21/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $573,000 Trans-NIH Recovery Act Research Support The emerging obesity pandemic is driving an alarming increase in the prevalence of insulin resistant forms of diabetes. The mechanisms whereby obesity leads to insulin resistance remain to be fully elucidated. Chronic caloric excess leads to increased del National Institutes of Health 1/11/2010
SCRIPPS RESEARCH INSTITUTE, THE $570,000 Trans-NIH Recovery Act Research Support We intend to use chemical screening to identify novel inhibitors of infection by influenza virus H1N1 and their cellular or viral targets. Such inhibitors may permit the development of drugs that act in a new way to block influenza broadly, checking the r National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $568,560 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This project aims to develop, improve, and exploit new molecules, mostly genetically targetable, for measuring and/or manipulating neuronal messengers and signals such as calcium, glutamate, GABA, action potentials, su National Institutes of Health 9/28/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $566,581 Trans-NIH Recovery Act Research Support This stage one TRIP application will enable a phase II clinical trial of a new therapy to treat sickle cell disease (SCD) in two years. The basis of our proposal is our recent discovery that invariant NKT (iNKT) cells contribute importantly to tissue infl
This spending item is part of a $1,817,442 allocation. See details
National Institutes of Health 9/28/2009
WHITTIER INSTITUTE FOR DIABETES, THE $565,922 Trans-NIH Recovery Act Research Support Purpose and Expected Outcomes: The goal of this research is to adapt the methods used in the national trial Diabetes Prevention Program, DPP, to the specific needs of high-risk, low-income Latino women with a history of gestational diabetes. We will use
This spending item is part of a $597,109 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $560,363 UC-Irvine's NIDA MTA 14-YR follow-up study modification shall address the following study objectives during the modification period: Sample retention enhancement Strengthen existing MTA subject retention by enhancing the compensation of recruitment practi
This spending item is part of a $1,441,422 allocation. See details
National Institutes of Health 4/26/2010
SCRIPPS RESEARCH INSTITUTE, THE $553,942 Trans-NIH Recovery Act Research Support RhoGDI is a key regulator of both the Rho GTPase GDP/GTP activity cycle and the cytosol/membrane localization cycle. Our current understanding of RhoGDI regulation and the dynamics of its interactions with Rho GTPases during in vivo cell signaling remains
This spending item is part of a $1,114,299 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $553,902 Trans-NIH Recovery Act Research Support Our proposal directly addresses the Program Announcement (RFA-AI-10-003) goals of ?development of broadspectrum (innate immunity) immunotherapeutic that targets NIAID Priority Agents' and establishment of ?collaborations between researchers in different d
This spending item is part of a $703,902 allocation. See details
National Institutes of Health 8/02/2010
Cordan Const. Co, Inc. $548,120 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $546,818 Trans-NIH Recovery Act Research Support The project will procure, process and analyze knees from 100 humans age 20-90 at autopsy each year. The knees are analyzed macroscopically and by various imaging techniques. Tissues, cells, RNA, DNA and protein are isolated from the knees and distributed
This spending item is part of a $4,245,533 allocation. See details
National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $540,654 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We propose to conduct a first-ever comprehensive quantitative investigation of motor function in autism using simultaneous brain and movement imaging. A novel system developed by Co- Investigator Makeig and his colleag National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $538,211 Trans-NIH Recovery Act Research Support This proposal will delineate the structural features of a group o f Eph receptors (EphB2, EphA2, and EphA4) in their apo forms as well as in complex with their cognate ligands and peptides. These receptors are members of the largest receptor tyrosine kina National Institutes of Health 8/03/2009
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD $537,935 Trans-NIH Recovery Act Research Support Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS) are fatal motor neuron disorders for which no significant treatments currently exist. Delivery of a therapeutic agent across the blood brain barrier (BBB) to the central nervous system
This spending item is part of a $3,354,732 allocation. See details
National Institutes of Health 9/23/2009
SAN DIEGO, COUNTY OF $537,626 ARRA - Immunization ARRA-317 Immunization and Vaccines for Children Grants. This award will support efforts to plan, develop, and maintain a public health infrastructure for low income children and adults vaccinated against vaccine-preventable diseases.
This spending item is part of a $10,069,863 allocation. See details
Centers for Disease Control and Prevention 9/15/2009
MOUNTAIN HEALTH & COMMUNITY SERVICES, INC. $536,195 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Program - EHR Implementation - A number of benefits will stem from the realization of an integrated EHR/PMS system. Workflow in nearly every clinic domain will improve: patient registration will occur more quickly, ... Show more Health Resources and Services Administration 6/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $534,966 Trans-NIH Recovery Act Research Support We are studying the mechanism of the catalytic reaction that converts molecular nitrogen into ammonia by the bacterial enzyme nitrogenase. For the catalytically central iron-molybdenum cofactor duster in nitrogenase, we will examine geometric and electron
This spending item is part of a $732,121 allocation. See details
National Institutes of Health 8/18/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $534,149 Trans-NIH Recovery Act Research Support Autism is a lifetime disorder, but surprisingly little is known about the effects it has on the individual's abilities, needs, and experiences as he or she reaches and continues through adulthood. The first descriptions of autism spectrum disorders (ASDs) National Institutes of Health 9/18/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $526,625 Trans-NIH Recovery Act Research Support Host cell pathways are harnessed and inactivated by viruses during productive infection. In vitro replication systems have been useful for studying viral DNA replication mechanisms, but they fail to capture the full complexity of the cellular environment National Institutes of Health 6/18/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $525,250 Trans-NIH Recovery Act Research Support Type 1 diabetes (T1D) develops as control of autoreactive CD4 cells is lost, which occurs in part because of escalating responses of cells that escape regulation and are highly pathogenic. While many cell types contribute to this disease, ameliorating the National Institutes of Health 9/01/2009
SCRIPPS RESEARCH INSTITUTE, THE $522,225 Trans-NIH Recovery Act Research Support Hepatitis C virus (HCV) chronically infects 2-3% of the global population, predisposing the patients to chronic liver diseases and liver cancer. The most effective treatment for HCV infection employs a combination of pegylated interferon-alpha (IFN-a) and National Institutes of Health 5/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $522,225 Trans-NIH Recovery Act Research Support In light of the extreme mortality rates associated with human infection with avian influenza strains, the emergence of a pandemic influenza outbreak is of immense concern. Pandemic strains are thought to occur through the introduction of genetically dive National Institutes of Health 6/04/2009
SCRIPPS RESEARCH INSTITUTE, THE $522,225 Trans-NIH Recovery Act Research Support The overall purpose of the project is to investigate the role of miRNA in the actions of cocaine in the brain. Results obtained so far support the hypothesis of the present application that miRNAs are differentially regulated by cocaine and may play regul National Institutes of Health 5/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $522,225 Trans-NIH Recovery Act Research Support Pseudomonas aeruginosa is a common environmental microorganism; most prominent is the role of P. aeruginosa in patients suffering from cystic fibrosis, as lung defense functions are impaired. Importantly, a molecular mechanism underlies P. aeruginosa path National Institutes of Health 5/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $522,225 Trans-NIH Recovery Act Research Support We aim to develop new chemical tools optimized for structural studies of the HIV co-receptor CXCR4, attempting crystallization and structural determination of the receptors and its complexes. Chemical tools will be designed and optimized for stabilizing, National Institutes of Health 9/25/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $520,850 Trans-NIH Recovery Act Research Support Drug addiction is a major health problem in the U.S. Although there have been significant advances in our understanding the neurochemical changes in addiction, there is a need to develop new approaches and to identify novel targets for elucidating the mol National Institutes of Health 5/07/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $519,475 Trans-NIH Recovery Act Research Support Activation of NKT cells by cytomegalovirus: The innate immune response to pathogens is critical for the control of infection prior to the development of adaptive immunity. NKT cells with an invariant T cell antigen receptor (TCR) ? chain (iNKT cells) are National Institutes of Health 5/15/2009
LA MAESTRA FAMILY CLINIC, INC. $519,028 ARRA Health Center Integrated Services Development Initiative[g1] Increased Demand for Services; Creation of new jobs and increase access to medical and dental services for uninsured patients. The goals were to see 2,417 New Patients, 967 Uninsured patients and retain 5.35 FTE jobs. LMFC provided se... Show more Health Resources and Services Administration 3/27/2009
LA MAESTRA FAMILY CLINIC, INC $518,018 Increase services to extend hours to Saturdays from 9am to 2pm in two medical and two dental clinics. Increase jobs and increase access to uninsured people. Health Resources and Services Administration 3/27/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $517,498 Trans-NIH Recovery Act Research Support The project will procure, process and analyze knees from 100 humans age 20-90 at autopsy each year. The knees are analyzed macroscopically and by various imaging techniques. Tissues, cells, RNA, DNA and protein are isolated from the knees and distributed
This spending item is part of a $4,245,533 allocation. See details
National Institutes of Health 8/14/2009
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. $514,836 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This project applies genomic and high-throughput genetic strategies to the global health emergency of tuberculosis. It creates new resources that will bridge clinic and laboratory, and quicken research for new, cheaper
This spending item is part of a $3,994,132 allocation. See details
National Institutes of Health 9/29/2010
SCRIPPS RESEARCH INSTITUTE, THE $513,235 Trans-NIH Recovery Act Research Support This proposal is to study the biological significance of IgE isoforms in allergic disorders. IgE plays.a major role in allergic disorders, including asthma, atopic dermatitis. We focus on a specific form of IgE believed to be responsible for allergic s National Institutes of Health 5/07/2009
EPISCOPAL COMMUNITY SERVICES $512,799 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
HLN CONSULTING, LLC $501,100 Provide consulting support to the US Department of Health and Human Services, Office of the National Coordinator, State Health Information Exchange (HIE) Technical Assistance Program. Tasks include technical assistance consultations to states, developing
This spending item is part of a $10,615,345 allocation. See details
Program Support Center 3/31/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $501,025 Trans-NIH Recovery Act Research Support Dramatic advances in cancer treatment will depend on identifying new targets for therapeutics. Here we propose as a candidate target a novel phosphoinositide signaling pathway that we have discovered. We have identified a pathway involving the phosphoinos National Institutes of Health 6/01/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $500,000 Trans-NIH Recovery Act Research Support The Salk Institute for Biological Studies is a non-profit research institution devoted to making fundamental discoveries in the life sciences, the improvement of human health and the training of future generations of researchers. Salk is arguably one of t National Institutes of Health 7/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $500,000 Trans-NIH Recovery Act Research Support The overall purpose of the award is to determine whether pharmacological Inositol (1,4,5)Trisphosphate 3-kinase B (ItpkB)-inhibition could provide an avenue towards cost-effectively reducing detrimental T cell function and cytokine storm in swine influenz National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $500,000 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This project will establish a modern environmental SEM platform and automated ultramicrotome system for serial block-face scanning electron microscopy (SBFSEM) at the National Center for Microscopy and Imaging Research National Institutes of Health 12/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $500,000 Trans-NIH Recovery Act Research Support This shared instrumentation grant request funds to partially offset the cost of an upgrade of the current 3 Tesla whole body magnetic resonance imaging (MRI) system at the UCSD Center for Functional MRI (CFMRI). In comparison to our existing system, the u National Institutes of Health 2/18/2010
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $500,000 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (06) Enabling Technologies, and specific Challenge Topics, 06-AG-108 Technologies for obtaining genomic, proteomic, and metabolomic data from individual viable cells in complex tissues, and 06-DK-105 Enablin
This spending item is part of a $998,464 allocation. See details
National Institutes of Health 9/22/2009
SCRIPPS RESEARCH INSTITUTE, THE $499,961 Trans-NIH Recovery Act Research Support These ARRA funds will be used to purchase a special order configuration of the Becton Dickinson (BD) LSR II Flow Cytometer. This configuration of the BD LSR II has five lasers; (Blue laser/Red laser/Yellow-Green laser/Violet laser/UV laser) and the BD Hig National Institutes of Health 1/29/2010
SCRIPPS RESEARCH INSTITUTE, THE $499,950 Trans-NIH Recovery Act Research Support This Sl0 instrumentation award was used to purchase a hybrid linear ion trap-orbitrap mass spectrometer. The instrument will be dedicated to the study of protein dynamics using hydrogen/deuterium exchange (HDX) with a focus on the study of large protein c National Institutes of Health 4/01/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $499,706 Trans-NIH Recovery Act Research Support A group of 27 NIH funded investigators at UCSD requests funds to purchase a FEI Tecnai G2 Spirit BioTWIN transmission electron microscope (TEM) to continue to meet the ongoing and future demands of a variety of researchers within the Department of Cellula National Institutes of Health 1/25/2010
SCRIPPS RESEARCH INSTITUTE, THE $495,430 Trans-NIH Recovery Act Research Support The main objective of this project is to achieve a better understanding of how alcohol addiction and withdrawal affects neuronal communication in the central nervous system at levels of single neurons and neural circuits. Specifically, the collaborating s
This spending item is part of a $980,018 allocation. See details
National Institutes of Health 9/18/2009
SCRIPPS RESEARCH INSTITUTE, THE $495,255 Trans-NIH Recovery Act Research Support The development of the arylomycin class of natural product antibiotics, which kill bacteria via the novel mechanism of inhibiting type I bacterial signal peptidases and protein transport, has been abandoned because these compounds are not sufficiently pot National Institutes of Health 7/17/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $494,850 Trans-NIH Recovery Act Research Support Built in 1978, strategically located at the center of the Health Sciences Region on the campus of the University of California, San Diego, the Medical Teaching Facility vivarium includes 26 mouse housing rooms capable of holding 69 racks and over 11,000 b National Institutes of Health 6/08/2009
CONTROLTEC, INC. $492,512 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
SCRIPPS RESEARCH INSTITUTE, THE $492,101 Trans-NIH Recovery Act Research Support Crystallographic experiments require a reliable in-house X-ray facility for high throughput screening of crystal quality and cryoprotection conditions, and for high resolution data collection from many hundreds of protein crystals. The new equipment is re National Institutes of Health 2/04/2010
IMPERIAL BEACH COMMUNITY CLINIC $488,805 ARRA Health Center Integrated Services Development Initiative[g1] The purpose of this project is the creation of Nestor Community Health Center so that low-income and uninsured residents of Imperial Beach and South San Diego, CA will have increased access to affordable, high quality, primary health c... Show more Health Resources and Services Administration 6/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $486,094 Trans-NIH Recovery Act Research Support This supplement is designed to allow us to mine our recently published database of spatial and temporal gene expression in lymphoid and stomal cells in the thymus. Our goal is to identify new stomal-to-lymphnoid signals that regulate stage-specific devel National Institutes of Health 6/14/2010
SAN DIEGO, COUNTY OF $484,381 Aging Congregate Nutrition Services for States Provides additional funding to Area Agencies on Aging for Elderly Nutrition Congregate Meals Programs to feed seniors in need and to restore nutrition services and local food service positions eliminated due to cost increases and funding losses.
This spending item is part of a $6,585,441 allocation. See details
Administration on Aging 3/18/2009
SCRIPPS RESEARCH INSTITUTE, THE $484,358 Trans-NIH Recovery Act Research Support This application is focused on the design, synthesis and evaluation of potential biological probes and treatment agents for alcohol dependence based on their actions on the nociceptin (NOP) receptor. We seek to identify compounds thai act as partial agoni National Institutes of Health 5/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $480,018 Trans-NIH Recovery Act Research Support The main objective of this project is to achieve a better understanding of how alcohol addiction and withdrawal affects neuronal communication in the central nervous system at levels of single neurons and neural circuits. Specifically, the collaborating s
This spending item is part of a $980,018 allocation. See details
National Institutes of Health 9/18/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $474,750 Trans-NIH Recovery Act Research Support The main goal of the proposed research is to understand the architecture, dynamics, and function of complex assemblies involved in transcriptional activation of human immunodeficiency virus type-1 (HIV-1) gene expression. HIV-1 encodes a transcriptional National Institutes of Health 7/23/2009
SCRIPPS RESEARCH INSTITUTE, THE $474,750 Trans-NIH Recovery Act Research Support The long term goal of these studies is to define the innate host-virus interactions that occur during hepatitis C virus (HCV) infection with the hope that this will lead to novel therapeutic approaches to this disease. Using a robust cell culture model of National Institutes of Health 9/11/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES $473,500 Trans-NIH Recovery Act Research Support Our goal is to understand the induction of HIV-1 transcription by the viral Tat protein, and its connection to other steps needed to process viral mRNAs and facilitate their export out of the nucleus. The HIV-1 Tat protein works with the host cell P-TEFb National Institutes of Health 9/11/2009
SCRIPPS RESEARCH INSTITUTE, THE $472,841 Trans-NIH Recovery Act Research Support The overall objective of this application is to find out which non-protein-coding RNAs are differentially expressed in Alzheimer's disease patients. We will create an inventory of nonprotein-coding RNAs by performing extensive sequencing of RNA samples fr National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $463,500 Trans-NIH Recovery Act Research Support This application responds to RFA-DA-09-016, Behavioral Pharmacology and Genetics: Translating and Targeting Individual Differences, and describes studies that will determine the genetic basis for individual differences in the effects of amphetamine (AMPH) National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $463,500 Trans-NIH Recovery Act Research Support Cognitive and motor impairments seen in methamphetamine (meth) dependence are often unrelated to drug use parameters such as length of abstinence, lifetime consumption, chronicity, mode of delivery, etc. This suggests the possibility of individual differe National Institutes of Health 9/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $460,747 ARRA - Prevention and Wellness--Communities Putting Prevention to Work The four evaluation projects that will be implemented under this project for enhanced evaluation are: 1.) Implementation of a sustainable community-wide BMI surveillance system through linkage of health care providersG?? EHRs to ... Show more
This spending item is part of a $1,768,581 allocation. See details
Centers for Disease Control and Prevention 9/28/2010
SCRIPPS RESEARCH INSTITUTE, THE $459,841 Trans-NIH Recovery Act Research Support We recently developed a unique reagent that combines the functions of an anthrax antitoxin and vaccine in a single compound. This reagent is based on multivalent display of the anthrax toxin receptor, ANTXR2, on the surface of an icosahedral insect virus.
This spending item is part of a $522,226 allocation. See details
National Institutes of Health 5/29/2009
KOCH-ARMSTRONG GENERAL ENGINEERING INC $459,150 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
ILLUMINA, INC. $457,844 Instruments for Genetic Analysis products and use. Health and Human Services, Department of 3/23/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $457,677 Trans-NIH Recovery Act Research Support Overall Purpose: The soil environment constitutes a very complex and competitive ecological niche occupied by numerous species of microbes. Within this niche, filamentous fungi employ a diverse array of bioactive compounds, termed natural products, to me
This spending item is part of a $1,188,187 allocation. See details
National Institutes of Health 8/16/2010
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $457,500 Trans-NIH Recovery Act Research Support Protein deubiquitination in lymphocyte signaling: The long-term goal of this laboratory is to understand the process of ubiquitin conjugation in the regulation of immune responses. Protein ubiquitination is carried out by a cascade of enzymatic reactions National Institutes of Health 5/22/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $457,032 Trans-NIH Recovery Act Research Support Viruses and Autoimmunity: P01: The hypothesis that human enterovirus infections have the potential to accelerate type 1 diabetes (T1D) onset in humans is well supported by both observational and experimental data. However, epidemiological data as well as National Institutes of Health 9/17/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $455,175 Trans-NIH Recovery Act Research Support We seek to identify common factors by which OA initiates and develops following normal loading of abnormal joint tissues (genetic model) or after abnormal loading of normal joints (post-traumatic/surgical model). Goal: To identify common factors by which
This spending item is part of a $4,140,386 allocation. See details
National Institutes of Health 9/16/2010
NORTH COUNTY CLINICAL RESEARCH, INC. $454,813 Trans-NIH Recovery Act Research Support Project Title: A Six-Month, RCT of Probuphine Safety and Efficacy in Opioid Addiction. We are conducting a six-month, randomized, placebo and active-controlled, multicenter clinical trial of Probuphine in patients with opioid dependence for the purpose
This spending item is part of a $7,586,848 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $452,013 Trans-NIH Recovery Act Research Support The approach of this highly collaborative grant is to combine the chemistry program of William Fenical at the Scripps Institution of Oceanography with the antibiotics pharmacology and discovery program of Victor NizetG??s laboratory at the UCSD School of National Institutes of Health 9/23/2009
SCRIPPS RESEARCH INSTITUTE, THE $451,431 Trans-NIH Recovery Act Research Support In the absence of a vaccine, there is an urgent need for the development of safe and effective microbicides. Microbicides are defined as vaginally applied products that prevent transmission of HIV. Recently, we identified a short peptide called Virocide, National Institutes of Health 7/22/2009
Western Foundations & Shoring, Inc. $451,348 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
ILLUMINA, INC. $449,924 PhiX Control and Sequencing Primer (100 Lanes) 5 DGE Small RNA Sample Prep Kit (1002698) ChIP-Seq Sample Preparation Kit 4 PE Sample Prep Kit mRNA-Seq 8 sample prep kit Multiplexing Sample Preparation Oliogonucleotide Kit cBot Paired End cluster Generatio National Institutes of Health 9/24/2010
SCRIPPS RESEARCH INSTITUTE, THE $446,877 Trans-NIH Recovery Act Research Support Renal transplantation is the treatment of choice for patients with renal failure, but acute and chronic allograft failure remains a critical problem for the transplant recipient. Infections are an independent factor that contributes to renal allograft fa
This spending item is part of a $515,033 allocation. See details
National Institutes of Health 6/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $445,329 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Recent developments in two-photon laser scanning microscopy (TPLSM) in combination with improvement of fluorescent calcium indicators have opened an unprecedented possibility for in vivo imaging of neuronal activity. T National Institutes of Health 5/21/2009
SCRIPPS RESEARCH INSTITUTE, THE $441,606 Trans-NIH Recovery Act Research Support Of two vaccine candidates tested in rats at the Scripps-based Koob lab one was found to be superior and advanced to the rat self administration studies. This vaccine evoked anti-cocaine titers of about 106 and in a parallel study using locomotor behavior
This spending item is part of a $3,840,375 allocation. See details
National Institutes of Health 9/30/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $439,920 Trans-NIH Recovery Act Research Support This award is to help support the replacement of an existing older cell sorter instrument within a core facility with a new upgraded model, a MoFlo XDP High Speed Cell Sorter manufactured by Beckman Coulter. The requested new instrument represents much im National Institutes of Health 5/20/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $439,899 Trans-NIH Recovery Act Research Support Peripheral arterial disease (PAD) is a highly prevalent, frequently morbid manifestation of systemic atherosclerosis, but relatively little attention has been paid to the epidemiology and risk factors for PAD. Endothelial dysfunction and its relationship
This spending item is part of a $1,967,319 allocation. See details
National Institutes of Health 8/28/2009
SAN DIEGO FAMILY CARE $439,855 ARRA Health Center Integrated Services Development Initiative[g1] San Diego Family Care has used IDS funding to meet expanding community demand for medical care by uninsured patients. During this past quarter, and throughout the entire grant period, we utilized IDS funds to maintain the two new jobs ... Show more Health Resources and Services Administration 3/27/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $439,814 Trans-NIH Recovery Act Research Support Project Summary: Cortical circuits are composed of a complex network of many neuron types. Their function is dependent on how neurons are interconnected, how the connections function, and how the information delivered to individual neurons is integrated w National Institutes of Health 9/02/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $433,295 Trans-NIH Recovery Act Research Support Title: Pre-clinical and Clinical Studies of Cobinamide, a New Cyanide-Detoxifying Agent This is a supplement to the above research project. The goal of the parent project is to develop cobinamide, a vitamin B12 analog, as a cyanide antidote. Cyanide i National Institutes of Health 9/25/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $430,705 Trans-NIH Recovery Act Research Support MOLECULAR ALGORITHMICS FOR PHARMACOLOGICAL INTERVENTIONS This proposal originates from discussions between scientists from different scientific fields: Drosophila aging physiology, information theory, statistics, bioengineering and systems biology. Biolog National Institutes of Health 7/20/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $430,705 Trans-NIH Recovery Act Research Support Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that form transmembrane, cation-permeable channels which open upon agonist binding. iGluRs are the major mediators of excitatory synaptic transmission in the central nervous system (CNS National Institutes of Health 8/14/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $430,705 Trans-NIH Recovery Act Research Support Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that form transmembrane, cation-permeable channels which open upon agonist binding. iGluRs are the major mediators of excitatory synaptic transmission in the central nervous system (CNS National Institutes of Health 8/14/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $429,750 Trans-NIH Recovery Act Research Support Here we will leverage the biochemical and EM sample preparation protocols to initiate robust acquisition of high-resolution cryo-images of key structural states along the pathway of inflammasome assembly. Achieving this goal will provide the baseline towa National Institutes of Health 7/12/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $426,875 Trans-NIH Recovery Act Research Support Tropical malaria, caused by the parasite Plasmodium falciparum, is responsible for up to three million deaths each year. Since the parasite develops resistance against most clinically available drugs, novel antimalarial drugs are urgently needed. Glucose- National Institutes of Health 8/01/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $425,537 Trans-NIH Recovery Act Research Support ARRA Supplement funds are requested to amplify and accelerate the design, building and testing of the Large Size (3Kx4K pixels) Direct Detection Device (DDD) currently supported by the R01 RR018841 grant by the NCRR titled ?A Completely New Camera System National Institutes of Health 9/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $424,875 Trans-NIH Recovery Act Research Support Congenital infection with human cytomegalovirus (HCMV) occurs in approximately 40,000 infants a year in the United States annually and is the leading viral cause of birth defects. These problems together with the severe disease that HCMV causes in solid o National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $424,875 Trans-NIH Recovery Act Research Support T helper cells in lymphoid tissues adopt multiple cell fates that regulate inflammation. At the G-I mucosa, their dominant phenotype is of Treg cells. Mucosal adjuvants, by overriding the tolerant impact of mucosal Treg cells, are unique tools for dissect National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $424,875 Trans-NIH Recovery Act Research Support Regulation of gene transcription in the gonadotrope is a key regulatory step that determines the levels of gonadotropin hormones and therefore, regulates gonadal function. Gametogenesis and steroidogenesis in both sexes are controlled by these two hormone National Institutes of Health 5/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $424,873 Trans-NIH Recovery Act Research Support Obesity is a burgeoning public health problem that is associated with an adverse metabolic profile and higher levels of morbidity and mortality from multiple causes. Current methods for assessing obesity focus on either nonspecific measures of overall bod National Institutes of Health 9/18/2009
Community Health Improvement $422,782 ARRA - Prevention and Wellness--Communities Putting Prevention to Work To promote improved nutrition, the County of San Diego will address regional food systems and the establishment of a San Diego-based food distribution center, link local food demand to supply, and increase access to healthy foods,... Show more
This spending item is part of a $16,105,299 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $420,206 Trans-NIH Recovery Act Research Support We originally proposed an 14 month, milestone-driven, benchmarked research plan that extends a parent P20 Center grant focusing on bio-therapeutics development. The research was proposed to be executed by 6 newly hired academic research and technical posi National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $420,055 Trans-NIH Recovery Act Research Support Glycoconjugates play crucial roles in many fundamental biological processes, and changes in glycan structure correlate with certain diseases and disorders. The large number of biological activities attributed to glycans is due in part to their interaction National Institutes of Health 4/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $418,908 Trans-NIH Recovery Act Research Support Title: High Content Screens of Neuronal Development for Autism Research. Disrupted neural development is thought to underlie autism and related disorders such as Rett syndrome, but the mechanisms are unknown and possibly highly diverse. This pilot proje National Institutes of Health 9/17/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $418,301 Trans-NIH Recovery Act Research Support This project seeks to expand the scope of a project that is directed at understanding the role of nuclear Abl tyrosine kinase in DNA damage-induced cell death response. DNA damage inducers, i.e., genotoxins, are some of the most effective agents in cancer National Institutes of Health 9/18/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $416,999 Trans-NIH Recovery Act Research Support For Project 1, we plan to block excessive NMDAR activation based on a novel family of NMDAR subunits, the NR3 family. We are developing ligand-binding domain (LBD)-derived screening assays to screen ligands selective for the NR3 subunit of the NMDAR. Thes National Institutes of Health 9/30/2010
SCRIPPS RESEARCH INSTITUTE, THE $410,382 Trans-NIH Recovery Act Research Support The proposed research will investigate the spectrum of changes in gene expression during genotoxic stress. Particular focus will be on genes normally expressed in preparation for DNA replication and repair of DNA damage. This wilt be correlated with the c National Institutes of Health 8/13/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $409,890 Trans-NIH Recovery Act Research Support Heart failure has reached epidemic proportions in the United States and is responsible for nearly 500,000 deaths each year. The majority of heart failure cases is now the result of infarction-induced left ventricular (LV) remodeling. The lack of well-esta
This spending item is part of a $1,552,066 allocation. See details
National Institutes of Health 8/14/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $408,651 Trans-NIH Recovery Act Research Support In the present investigation we will use competitive peptide inhibitiors in an attempt to disrupt the association between ITK and SLP 76 and inhibit the activation of ITK in live cells. This presumably should create a condition that would mimic the situat National Institutes of Health 5/14/2009
SAN DIEGO STATE UNIVERSITY $407,691 ARRA - Prevention and Wellness--Communities Putting Prevention to Work The four evaluation projects that will be implemented under this project for enhanced evaluation are: 1.) Implementation of a sustainable community-wide BMI surveillance system through linkage of health care providersG?? EHRs to ... Show more
This spending item is part of a $1,768,581 allocation. See details
Centers for Disease Control and Prevention 9/28/2010
SAN DIEGO STATE UNIVERSTIY FOUNDATION $406,175 Trans-NIH Recovery Act Research Support Activation of thymus-derived (T) lymphocytes is critical in the immune response to pathogens, autoimmunity, and in allergic responses. Activation of T cells through their anitgen receptors (TCR) involves a complex process of biochemical events critically National Institutes of Health 5/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $402,357 Trans-NIH Recovery Act Research Support Modern electron cryo-microscopy and computer-based, 3D image reconstruction techniques are revolutionizing the way structures of large and complex biomacromolecular machines are studied. These methods provide keys to understanding at the molecular level h National Institutes of Health 5/12/2009
SCRIPPS RESEARCH INSTITUTE, THE $401,025 Trans-NIH Recovery Act Research Support The goal of our program project is to understand the mechanisms of drug resistance in treated HIV infected patients. The work supported by the supplement facilitates these studies in two areas. First it enables us to expand our studies to include the HIV National Institutes of Health 9/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $400,000 Trans-NIH Recovery Act Research Support JCVI will develop a method to measure gene expression in individual cancer cells obtained from human blood. These circulating cancer cells (CTCs) are very rare but can be responsible for the spread of cancer throughout the body by metastasis. With new s
This spending item is part of a $997,969 allocation. See details
National Institutes of Health 9/25/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $395,491 Trans-NIH Recovery Act Research Support The ability to conduct real-time, sequential in viva imaging of small animals is an important extension of animal models developed to study human diseases, and a prerequisite to translation of basic science discoveries to clinical applications. This propo National Institutes of Health 3/11/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $392,520 Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) remains a major unmet medical need despite recent advances in therapy. The pain and loss of function resulting from chronic synovitis are due to a variety of influences, including activated adaptive and innate immune responses. I
This spending item is part of a $893,569 allocation. See details
National Institutes of Health 9/24/2009
MAGNESENSORS, INC. $390,199 Trans-NIH Recovery Act Research Support Nanotechnology based magnetic detection for rare cell assays. This supplement is requested to add a highly experienced scientist to significantly enhance and accelerate our existing Phase II SBIR by bringing the fabrication of the magnetic nanoparticle r National Institutes of Health 9/29/2009
HOWARD'S RUG COMPANY OF SAN DIEGO, INC. $390,080 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $385,942 Trans-NIH Recovery Act Research Support Overall Purpose/Goal: Extreme heat events (EHE) remain the leading cause of weather-related morbidity and mortality in the United States. Goal: To develop for the State of California an analytic framework to: (1) advance knowledge of the relations between
This spending item is part of a $996,394 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $384,820 Trans-NIH Recovery Act Research Support The signal transduction events within endothelial cells (ECs) or macrophages which encode the complex cascade of events required for angiogenesis are poorly understood. The objective of this proposal is to gain insight into the regulatory network in ECs o National Institutes of Health 3/22/2010
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $383,639 Trans-NIH Recovery Act Research Support Transcription factors (TF) have a crucial role in controlling gene expression, and exploring their molecular targets, binding partners and mode of regulation is essential to understand any plant biological process. Arabidopsis offers some unique advantage
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $383,176 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $382,474 Trans-NIH Recovery Act Research Support ParA systems play an important role in chromosome segregation and are responsible for the segregation of many bacterial plasmids. This proposal focuses on the ParA partitioning system of E. coli plasmid F, which consists of the SopA (ParA) ATPase, the So National Institutes of Health 9/24/2009
SCRIPPS RESEARCH INSTITUTE, THE $382,225 Trans-NIH Recovery Act Research Support To address whether small molecules can be identified that inhibit differentiation of hESCs in the absence of growth factors/cytokines for long-term self-renewal of hESCs (in a way conceptually similar to the function/mechanism of pluripotin in mESCs), we
This spending item is part of a $522,225 allocation. See details
National Institutes of Health 9/29/2009
LA JOLLA BIOENGINEERING INSTITUTE $382,064 Trans-NIH Recovery Act Research Support The goal of this supplement project is to add molecular modeling skills and capability at molecular dynamics (MD) and ab initio levels to the research methods of the parent grant. The central hypothesis is that the plasma membrane of endothelial cell a National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $380,719 Trans-NIH Recovery Act Research Support Circadian clocks have evolved in diverse organisms, from bacteria to humans, where they time a host of physiological processes to occur in a coordinated manner throughout the 24-h day. The overall goal of the parent grant is to understand the mechanism by National Institutes of Health 8/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $379,800 Trans-NIH Recovery Act Research Support The applicant has been in the forefront of studies of the function of PB1-F2. Studies in cells have shown that PB1-F2 targets the mitochondrial membrane where it interacts with AMT3 and VDAC1 of the permeability transition pore complex causing the release
This spending item is part of a $7,935,507 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $375,350 Trans-NIH Recovery Act Research Support An underlying viral infection can modulate secondary pathogen encounters in different ways. For instance, virus infections such as HIV or Measles are associated with immunosuppression and enhanced susceptibility to opportunistic infections, resulting in m National Institutes of Health 6/03/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $374,431 Trans-NIH Recovery Act Research Support Individuals with anorexia nervosa (AN) have aberrant feeding behavior, disturbances of emotionality and impulse control, and have high rates of relapse after weight restoration. There is no proven treatment that reverses symptoms. Although imaging studies
This spending item is part of a $424,875 allocation. See details
National Institutes of Health 5/07/2009
SCRIPPS RESEARCH INSTITUTE, THE $366,334 Trans-NIH Recovery Act Research Support The overall purpose of the research project is to develop, using click chemistry approaches, novel antibiotics with improved activity against the major periodontal pathogens, bacteria that cause serious gum disease and tooth loss. Timely and cost-effectiv
This spending item is part of a $961,612 allocation. See details
National Institutes of Health 9/17/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $363,171 Trans-NIH Recovery Act Research Support The purchase of a bioluminescent imaging (BLI) system is requested for the core imaging facility at the University of California San Diego Medical Center (UCSDMC), Hillcrest. While various microscopes, and non-invasive imagers (i.e. magnetic resonance ima National Institutes of Health 2/20/2010
RETROVIROX, INC. $356,280 Trans-NIH Recovery Act Research Support Small-molecule inhibitors of HIV-induced receptor downmodulation These ARRA funds will be utilized to screen a library of 50,000 small-molecules with a flow-cytometry based assay. The assays will be optimize to identify inhibitors of the HIV-induced down National Institutes of Health 4/05/2010
SCRIPPS RESEARCH INSTITUTE, THE $355,550 Trans-NIH Recovery Act Research Support While integrin- and growth factor-mediated signaling pathways are thought to be critical for tumor invasion and metastasis, much remains to be elucidated regarding the specific kinases, phosphatases, proteases, and adaptor proteins that are essential for
This spending item is part of a $651,648 allocation. See details
National Institutes of Health 8/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $354,965 Trans-NIH Recovery Act Research Support Gliomas are the most common type of human brain tumors. Based on clinical and pathological criteria, they can be classified into four grades. The grade III and IV gliomas are malignant tumor. Grade IV glioma is commonly known as glioblastoma, which is one National Institutes of Health 9/08/2009
UNIVERSITY OF SAN DIEGO $353,376 Trans-NIH Recovery Act Research Support The research plan involves the development of the copper-catalyzed diboration of carbonyls and imines. The synthetic utility of the resulting diboration products will be established to provide access to challenging functional group arrays. National Institutes of Health 8/19/2011
UNIVERSITY OF CALIFORNIA, SAN DIEGO $350,000 Trans-NIH Recovery Act Research Support This supplemental award provides funds to support project 2 and to accelerate the tempo of the parent grant. There are two specific tasks: Task 1: Systematically study and optimize the circulation lifetime of drug delivery motherships and nanoparticle pay
This spending item is part of a $500,000 allocation. See details
National Institutes of Health 9/15/2009
SCRIPPS RESEARCH INSTITUTE, THE $344,669 Trans-NIH Recovery Act Research Support The parent grant (R01 CA129484) entitled A Cellular and Molecular Analysis of the Intravasation Step in Tumor Metastasis was dedicated to investigating the overall process of intravasation, the entry of primary tumor cells into the vasculature of the host National Institutes of Health 9/02/2009
SCRIPPS RESEARCH INSTITUTE, THE $342,226 Trans-NIH Recovery Act Research Support A major goal in neurobiology is the identification of functional neuronal pathways. Classical anatomical tracing techniques allow connectivity between brain regions to be determined. Lesion studies and anatomically restricted infusioon of pharmacologica National Institutes of Health 3/15/2010
LA JOLLA BIOENGINEERING INSTITUTE $340,200 Trans-NIH Recovery Act Research Support During the parent grant-related activities, we showed that administration of the calcium channel blocker nimodipine in combination with the antimalarial drug artemether to mice with cerebral malaria (CM) doubles the survival rates. This revision will addr National Institutes of Health 8/01/2009
ST. VINCENT DE PAUL VILLAGE, INC. $338,410 ARRA Health Center Integrated Services Development Initiative[g1] ARRA-Capital Improvement Program. This project involves the renovation of the current lobby of the Village Family Health Center (VFHC) at St. Vincent de Paul Village to allow for better patient flow and increased visits. One additional... Show more Health Resources and Services Administration 6/25/2009
SAN DIEGO STATE UNIVERSITY $327,773 Trans-NIH Recovery Act Research Support It is the over all goal of this project to develop a novel chemotherapeutic agent based on the San A scaffold. It is our hypothesis that analogs of San A with even greater potency and selectively can be synthesized by modifying key structural features ide National Institutes of Health 5/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $327,576 ARRA - Strategic Health IT Advanced Research Projects (SHARP) We propose research that will generate a framework of open source services that can be dynamically configured to transform HER data into standards-conforming, comparable information suitable for large-scale analyses, inferencing, and integ... Show more
This spending item is part of a $15,000,000 allocation. See details
Health and Human Services, Department of 3/19/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $324,820 Trans-NIH Recovery Act Research Support Medical decision support tools are increasingly available on the Internet and are being used by lay persons as well as health care professionals. The goal of some of these tools is to provide an individualized prediction of future health care related even National Institutes of Health 9/10/2010
SAN DIEGO STATE UNIVERSTIY FOUNDATION $319,248 Trans-NIH Recovery Act Research Support The overall goal of the SDSU IMSD Program is to increase the number of SDSU underrepresented minority students who will enter Ph.D. programs in the biomedical sciences. Through year-round research training, mentoring and academic and professional developm National Institutes of Health 7/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $313,600 Trans-NIH Recovery Act Research Support The goal of this proposal is to elucidate the eukaryotic DNA damage response through an integrated experimental/computational approach leading to in-silico models of signaling and regulatory networks. Comparative modeling of the networks induced by differ National Institutes of Health 9/03/2009
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES, INC. $313,200 Trans-NIH Recovery Act Research Support This study develops novel approaches based on the p14ARF tumor suppressor and Spermidine-CoA-based inhibitors of histone acetylation to improve cellular responses to topoisomerase I-targeted chemotherapies and reverse therapy resistance, a major obstacle National Institutes of Health 9/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $312,755 Trans-NIH Recovery Act Research Support Cardiac ultrasonography continues to be used frequently in experimental medicine for certifying in vivo the physiologic and anatomic characteristics of the cardiovascular system. Advances in ultrasound technologies now provide, both for embryos and small National Institutes of Health 1/27/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $310,149 Trans-NIH Recovery Act Research Support Function and Regulation of the Human Splicing Factor SC35 was designed to study the role of SR proteins in regulated RNA processing, focusing on the following 3 specific aims: 1. Analyze the splicing program during heart development 2. Determine the funct National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $309,000 Trans-NIH Recovery Act Research Support The purpose of this Supplement to the Comprehensive SDSU-UCSD Cancer Center Partnership (U54 CA132379) is to achieve objectives that are an extension of the parent grant. This Supplement Community Health Educator Administrative Supplement directly address National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $309,000 Trans-NIH Recovery Act Research Support The human DISC1 gene has been proposed to be one of the most compelling susceptibility genes for schizophrenia, a chronic, severe mental disorder imposing a high financial burden on the quality of life of the patients, their families and communities. Rece National Institutes of Health 6/02/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $305,174 Trans-NIH Recovery Act Research Support This award seeks acquisition of a TOF mass spectrometer coupled with an HPLC for accurate mass determination of small molecules such as natural products, organometallic compounds, nucleic acids and non-polar organic synthetic intermediates that are genera National Institutes of Health 4/22/2010
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $302,864 Trans-NIH Recovery Act Research Support This program project examines the structure, biosynthesis, and roles of carbohydrates in cell-cell interaction. The proposed projects were borne-out from our strong collaborative research activities in the previous funding period. This program project i
This spending item is part of a $331,124 allocation. See details
National Institutes of Health 9/10/2009
SCRIPPS RESEARCH INSTITUTE, THE $300,775 Trans-NIH Recovery Act Research Support This project will determine the HIV-l envelope changes necessary for the virus to use different cell surface molecules for entry. Recent progress has shown HIV-l subtype-specific preference for alternative coreceptors, and suggests different target cell p National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $299,750 ARRA ? Equipment to Enhance Training for Health Professionals The UCSD-SDSU General Preventive Medicine Residency (PMR) proposes this one-year project in response to the ?Equipment to Enhance Training for Health Professionals? (EETHP) initiative. Our residency has been fully accredited to train physi... Show more Health Resources and Services Administration 9/03/2010
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $299,348 Trans-NIH Recovery Act Research Support This administrative supplement is a request for personnel to increase the tempo of research on the R01 grant 'HIV-1 Vpu and BST-2/CD317' by maintaining and increasing the current level of technical support and employment on this project. Specifically, our National Institutes of Health 9/12/2009
BORREGO COMMUNITY HEALTH FOUNDATION $299,210 ARRA Health Center Integrated Services Development Initiative[g1] Increased Demand for Services. The funds in this gratn were used for the hiring of two new employees to do outreach and eligibilty services for our patients. We hope to reach as many people and as possible and provide them with healt... Show more Health Resources and Services Administration 3/27/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $299,000 Trans-NIH Recovery Act Research Support The purpose of this ARRA Administrative Supplement is to plan for the development of a Minority Biospecimens/Biobanking Geographic Management Program (BMaP) hub for Region 6. First, a project coordinator and a graduate student research assistant will be h National Institutes of Health 9/23/2009
AMERGROUP INC., THE $298,094 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $298,075 ARRA - Scholarships for Disadvantaged Students The UCSD Health Sciences Financial Aid Office will award SDS funding to disadvantaged medical and pharmacy students for whom the cost of attendance would constitute a severe financial hardship. There are no former recipients of EFN and FADHPS funding at... Show more Health Resources and Services Administration 6/14/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $296,098 Trans-NIH Recovery Act Research Support While integrin- and growth factor-mediated signaling pathways are thought to be critical for tumor invasion and metastasis, much remains to be elucidated regarding the specific kinases, phosphatases, proteases, and adaptor proteins that are essential for
This spending item is part of a $651,648 allocation. See details
National Institutes of Health 8/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $294,889 Trans-NIH Recovery Act Research Support To investigate the therapeutic implications of the current paradigm that autoimmune disease can result from defects in the clearance of dying/apoptotic cells, we have conducted preliminary studies that have shown that infusions of a natural antibody deriv National Institutes of Health 8/01/2009
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $294,797 Trans-NIH Recovery Act Research Support Project Summary/Abstract for more than 30 years, there has been a nationwide effort to encourage students from underrepresented ethnic minorities to pursue careers I nthe sciences. Despite widespread intervention programs, there remains a significant une National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $291,116 Trans-NIH Recovery Act Research Support Atrial fibrillation (AF) is the most common heart rhythm disorder, affecting 2.2 million individuals in the United States alone, and is a major cause of morbidity and mortality. Current methods to eliminate AF with anti-arrhythmic drugs and ablation remai National Institutes of Health 7/16/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $290,636 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $289,516 Trans-NIH Recovery Act Research Support This is an administrative supplement to an active R01 grant (1 R01 HL090975-01) funded by the NHLBI. The parent grant investigates the role of adiposity on vascular inflammation, immune cell activation, and neuroendocrine responses in 200 prehypertensive National Institutes of Health 7/16/2009
ALPHA KAPPA ALPHA HEADSTART PROGRAM INC $288,801 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $285,389 Trans-NIH Recovery Act Research Support Somatic stem cells appear to have their greatest impact on stroke therapeutics not by literally replacing cells but by protecting host neural cells & circuitry from progressive damage as well as catalyzing endogenous host regenerative responses. When such
This spending item is part of a $532,889 allocation. See details
National Institutes of Health 6/12/2009
SCRIPPS RESEARCH INSTITUTE, THE $284,850 Trans-NIH Recovery Act Research Support This competitive revision application extends from MH051699, Receptor-mediated lysophosphatidic acid (LPA) signaling in cortical development that is focused on LPA signaling as a novel, lipid influence on cerebral cortical development. It is responsive to National Institutes of Health 9/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $284,527 Trans-NIH Recovery Act Research Support This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Plasmodium vivax malaria, a leading health proble National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $284,525 Trans-NIH Recovery Act Research Support The main approach outlined in the original application was to enhance the specificity of tumor targeting by designing mechanisms to amplify the targeting. We believe that this is still an approach unique to us in the nanobiotechnology research arena. This
This spending item is part of a $569,049 allocation. See details
National Institutes of Health 8/31/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $284,525 Trans-NIH Recovery Act Research Support The main approach outlined in the original application was to enhance the specificity of tumor targeting by designing mechanisms to amplify the targeting. We believe that this is still an approach unique to us in the nanobiotechnology research arena. This
This spending item is part of a $569,049 allocation. See details
National Institutes of Health 8/31/2009
SYNERGY CLINICAL RESEARCH CENTER $282,916 Trans-NIH Recovery Act Research Support Project Title: A Six-Month, RCT of Probuphine Safety and Efficacy in Opioid Addiction. We are conducting a six-month, randomized, placebo and active-controlled, multicenter clinical trial of Probuphine in patients with opioid dependence for the purpose
This spending item is part of a $7,586,848 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $282,787 Trans-NIH Recovery Act Research Support Chronic Viral infections represent a major health problem and have been associated with deficient CD8 T cells responses. We recently found that attenuation of TGF?+? signaling during chronic Lymphocytic choriomeningitis virus infection results in increase National Institutes of Health 9/29/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $281,814 Trans-NIH Recovery Act Research Support For two years, four investigators will each hire a new full-time employee to identify and validate a novel therapeutic strategy for a group of rare inherited metabolic disorders, the Congenital Disorders of Glycosylation-Type I (CDG-I). These disorders re
This spending item is part of a $999,141 allocation. See details
National Institutes of Health 9/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $280,114 Trans-NIH Recovery Act Research Support The proposed work will establish national networking of scientists by providing a new software system (VIVO) and support for scientists using VIVO. Scientists using VIVO will be able to find other scientists and their work. Conversely, scientists using
This spending item is part of a $12,201,380 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $278,100 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The long-term goal of this proposal is to understand the molecular and cellular mechanisms of signal termination mediated by the novel phosphatase PHLPP (PH domain Leucine-rich repeat Protein Phosphatase; pronounced 'f National Institutes of Health 8/10/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $277,711 Trans-NIH Recovery Act Research Support The long-term goal of our research program is to understand the functional role of taste receptors (TRs) in pancreatic ?-cells. We have found that a novel class of nutrient-binding G-protein coupled receptors, TRs, is expressed in pancreatic ?-cells. We d National Institutes of Health 6/28/2010
SCRIPPS RESEARCH INSTITUTE, THE $277,100 Trans-NIH Recovery Act Research Support Hsp70 chaperones occur in all organisms and essentially all cellular compartments. Among their wide array of essential cellular functions, they facilitate folding of newly synthesized proteins; protect cells from damage such as aggregation that can occur
This spending item is part of a $351,081 allocation. See details
National Institutes of Health 9/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $275,846 Trans-NIH Recovery Act Research Support The overall goal of the parental grant (GM61905) is to understand the molecular basis of transport and selective inhibition of the lipid ABC flippase MsbA. We request supplemental funds for two post-doc associates (US citizens) and a Beckman (USA) JA-?26X National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $273,541 Trans-NIH Recovery Act Research Support The major goal of this Administrative Supplement to parent grant R01 CA94900 is to accelerate the tempo of scientific research by allowing us to appoint additional personnel to the project. The parent grant, which will remain active throughout the propose National Institutes of Health 8/27/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $269,726 Trans-NIH Recovery Act Research Support Real time quantitative multiplex analysis of cell-cell interactions, Award number: R21CA128718-01-A2, The objective of this award is the development of a platform for the parallel and time dependent analysis of cell-cell communication. The device will pro National Institutes of Health 9/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $269,294 Trans-NIH Recovery Act Research Support The major goals of this project are to elucidate the function and regulation of protein phosphorylation in the control of cell growth, differentiation, survival, and metabolism in response to various growth factors. We will particularly focus on the mamma National Institutes of Health 8/03/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $264,045 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Despite impressive advances in understanding cancer etiology and the development of novel therapeutic approaches, the most effective therapies for solid malignancies (carcinomas) remain surgery and radiotherapy. Althou National Institutes of Health 9/01/2009
SCRIPPS RESEARCH INSTITUTE, THE $261,113 Trans-NIH Recovery Act Research Support This project will help improve a method to genetically alter human embryonic stem cells in order to faithfully and easily measure the activity of several heart specific genes. This method, called gene targeting, will greatly facilitate development of pr
This spending item is part of a $492,990 allocation. See details
National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $258,534 Trans-NIH Recovery Act Research Support Type I interferons (IFNa/p) represent a group of cytokines that finds widespread clinical application in the treatment of autoimmune disorders such as multiple sclerosis, however; the mechanisms by which IFNa/p exert their beneficial effects remain elusiv National Institutes of Health 7/20/2010
SCRIPPS RESEARCH INSTITUTE, THE $258,302 Trans-NIH Recovery Act Research Support This project aims at determining the histamine receptor subtypes as well as of the A-type voltage-gated potassium channels present in preoptic and interior hypothalamic neurons involved int thermoregulation. National Institutes of Health 8/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $256,544 Trans-NIH Recovery Act Research Support Despite the great effort and resources that visual neuroscientists have dedicated to establishing a model for the organization of the human visual cortex, information on the histological characteristics of cortical areas is very limited. A web-based sea National Institutes of Health 9/30/2009
INDIAN HEALTH COUNCIL $255,980 ARRA - IHS Tribal Agreements This project will add solar panels to the facility of the main clinic. The project includes installing a 20-30kw Photo Voltaic system. Cost savings (15%-25%) will be immediately demonstrated through reduction of resources used for electricity. This will a Indian Health Service 1/25/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $253,194 Trans-NIH Recovery Act Research Support We propose to combine the best proven aspects of SBS with streamlined methods for DNA amplification and high-speed fluorescence imaging to develop and implement a platform for rapid and inexpensive genome resequencing and de novo sequencing. Our platform National Institutes of Health 9/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $252,120 Trans-NIH Recovery Act Research Support Vitamin A is clearly an essential nutrient, but its actions in the body are not clearly understood. Retinoic acid (RA) is a signaling molecule derived from vitamin A that regulates gene expression, thus providing a powerful mechanism through which vitami National Institutes of Health 9/18/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $251,186 Trans-NIH Recovery Act Research Support CRCNS: Integrated Empirical and Multiscale Modeling of Human Sleep Spindles. The overall goal of the proposed research is to determine how brain events at the biophysical level in the human brain influence the macroscopic recordings outside the skull. The National Institutes of Health 8/31/2009
CHILDREN OF THE RAINBOW HEAD START LLC $250,250 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $250,000 The purpose of the proposed modification is to facilitate discovery and use of resources relevant to drug abuse research by accelerating and increasing enhancements to the NIF system. Specifically, the following enhancements will be delivered: A)-?-? 10 National Institutes of Health 9/01/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $249,465 Trans-NIH Recovery Act Research Support The funds will be used to complete the HLA-typing of DNA specimens obtained from children participating in Pediatric AIDS Clinical Trials Group / International Maternal Pediatric Adolescent AIDS Clinical Trials Group protocols which will provide data to d
This spending item is part of a $255,702 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $248,220 Trans-NIH Recovery Act Research Support In the last decade collaborative networks of providers and experts have arisen to address health issues from Africa to Asia, the Caribbean to South America. This is highlighted by the global response to the earthquake in Haiti, where web-based groups prov National Institutes of Health 9/26/2010
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES, INC. $247,500 Trans-NIH Recovery Act Research Support Somatic stem cells appear to have their greatest impact on stroke therapeutics not by literally replacing cells but by protecting host neural cells & circuitry from progressive damage as well as catalyzing endogenous host regenerative responses. When such
This spending item is part of a $532,889 allocation. See details
National Institutes of Health 6/12/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $246,665 Trans-NIH Recovery Act Research Support The prevalence of non-alcoholic fatty liver disease (NAFLD) and its severe phenotype, non-alcoholic steatohepatitis (NASH), are increasing significantly in the United States in the adult and pediatric population. NAFLD is associated with obesity and meta
This spending item is part of a $361,206 allocation. See details
National Institutes of Health 9/30/2010
SALK INSTITUTE FOR BLOGICAL STUDIES $246,590 Trans-NIH Recovery Act Research Support The long-term goal of this work is to understand the molecular genetic mechanisms that underlie developmental complexity. Multicellularity has evolved multiple times in the history of life and has led to an explosion of eukaryotic diversity, including nov National Institutes of Health 7/17/2009
APERIO TECHNOLOGIES, INC. $245,707 ARRA Intramural Research Equipment: This requirement provides consolidated equipment for the NIAID (National Institute of Allergy and Infectious Diseases) Intramural Research Program for influenza studies. The deliverables include: 1 (one) ScanScope XT di National Institutes of Health 9/28/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $244,282 Trans-NIH Recovery Act Research Support Autism spectrum disorders (ASD) are pervasive developmental disorders characterized by abnormalities in a variety of social, communicative, and emotional behaviors, which occur in 0.67 percent of the population (Centers for Disease Control and Prevention, National Institutes of Health 8/25/2010
UNIVERSITY OF SAN DIEGO $241,159 ARRA - Nurse Faculty Loan Program 00 Health Resources and Services Administration 8/10/2009
SCRIPPS RESEARCH INSTITUTE, THE $239,179 Trans-NIH Recovery Act Research Support Our original proposal involved analyzing changes in transthyretin structure with aging and how the liver, its site of production, protected both itself and distant organs from damage produced by the misfolded molecule and the effects of transthyretin depo National Institutes of Health 9/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $238,920 Trans-NIH Recovery Act Research Support This proposal for an administrative supplement will allow completion of pediatric pharmacology studies performed as part of the Pediatric Pharmacology Research Network (PPRU) Network and hasten the acquisition of scientific knowledge that can be applied t National Institutes of Health 1/01/2008
UNIVERSITY OF CALIFORNIA, SAN DIEGO $238,605 Trans-NIH Recovery Act Research Support Cardiac remodeling is triggered in response to mechanical stress and various neurohumoral factors. We have recently discovered that protein kinase D (PKD), which has been scarcely studied in cardiomyocytes, plays a significant role to regulate cardiac hyp National Institutes of Health 7/16/2009
SAN DIEGO, COUNTY OF $238,465 Aging Home-Delivered Nutrition Services for States Provides additional funding to Area Agencies on Aging for Elderly Nutrition Home Delivered Meals Programs to feed seniors in need and to restore nutrition services and local food service positions eliminated due to cost increses and funding losses.
This spending item is part of a $3,242,063 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $237,970 Trans-NIH Recovery Act Research Support Oxidative modification of LDL is an important, if not obligatory, step that mediates the atherogenicity ofLDL. Many pathological conditions and environmental factors promote LDL oxidation, especially formation of early forms of oxidized LDL,termed minimal National Institutes of Health 7/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $234,019 Trans-NIH Recovery Act Research Support The overall scientific purpose of the award was to isolate and characterize aggressive and nonaggressive human pancreatic tumor cells. We expect that highly valuable cell variants will be characterized and that potential therapeutic targets for pancreatic National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $233,612 Trans-NIH Recovery Act Research Support There are resident populations of T cells in human epidermis and dermis, but the role of these T cells in wound healing has not been examined. We will determine the mechanisms of skin T cell function in wound healing and if these functions are unique to s National Institutes of Health 7/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $232,118 Trans-NIH Recovery Act Research Support This award is an administrative supplement for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group, specifically to provide supplemental funding for the Immune Activation Project; HIV-1 Project, P1032 and Ancestry Markers
This spending item is part of a $1,204,584 allocation. See details
National Institutes of Health 9/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $231,750 Trans-NIH Recovery Act Research Support The overall mission of the UCLA-UCSD DERC is to foster research in the prevention and treatment of diabetes and its complications and ultimately to improve the lives of patients with diabetes. This unique Center crossed institutional boundaries to harness National Institutes of Health 12/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $231,750 Trans-NIH Recovery Act Research Support Functional brain imaging using scalp-recorded electroencephalography (EEG) can be low cost, non-invasive, and highly mobile, with fine time resolution. The principal obstacle to its more widespread medical use has been the lack of adequate software to ext National Institutes of Health 9/29/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $231,575 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Understanding the cellular and molecular mechanisms of hazardous chemicals in our environment is a critical national objective. The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) was est National Institutes of Health 9/06/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $231,132 Trans-NIH Recovery Act Research Support In the skeletally mature individual, hyaline articular cartilage does not heal effectively when injured and the natural progression of acquired articular cartilage defects is predictably poor, commonly culminating in joint arthrosis. Physician and patient National Institutes of Health 9/22/2009
SCRIPPS RESEARCH INSTITUTE, THE $226,876 Trans-NIH Recovery Act Research Support Our goal is to understand the assembly of a model, non enveloped virus that is extremely accessible to the methods of biophysics and molecular genetics. Specifically we are interested in how the viral genome is replicated with the enzyme that the virus en National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $225,202 Trans-NIH Recovery Act Research Support Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a genetic form of cardiomyopathy, which is typically characterized by right but also recently left ventricular dysfunction, fibrotic/fatty replacement of the ventricle and ventricular a National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $224,035 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of California at San Diego (UCSD) and San Diego State University (SDSU) propose to continue a successful institutional research and academic career development award (IRACDA) program for postdoctoral sch
This spending item is part of a $279,875 allocation. See details
National Institutes of Health 9/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $220,740 Trans-NIH Recovery Act Research Support Despite being dependent on the same set of cytokines (IL-+7 and IL-15) for their survival, memory CD4-+ T cells generally display a shorter lifespan than memory coa' T cells. We will test the hypothesis that a reduced competitiveness of memory CD4-+ T cel National Institutes of Health 7/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $218,818 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Herpes simplex virus type 2 (HSV-2) is a medically important pathogen worldwide, with a prevalence rate of over 20% in the US. The physical pain and psychosocial stress due to recurrent herpetic genital lesions have pr National Institutes of Health 9/11/2009
SAN DIEGO HOSPICE AND PALLIATIVE CORPORATION $218,760 Trans-NIH Recovery Act Research Support Palliative care, a relatively new subspecialty, needs to build its evidence base supporting clinical practice. The Institute of Medicine has identified palliative care as a comparative effectiveness research priority, but increased scientific productivity
This spending item is part of a $7,175,320 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $216,883 Trans-NIH Recovery Act Research Support The CFAR Network of Integrated Clinical Systems (CNICS), headquartered at UAB, was funded in September 2006 via the R24 mechanism. This supplement is to fund increased capacity for sample repositorys at UAB and each of the designated CNICS sites through
This spending item is part of a $1,825,789 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $216,300 Trans-NIH Recovery Act Research Support Caveolae, mitochondria, and cardiac protection. The series of experiments proposed in the ARRA supplement request will determine if localized expression caveolin to mitochondria can serve as a novel therapeutic target for protecting the heart from ischemi National Institutes of Health 7/16/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $214,856 Trans-NIH Recovery Act Research Support Our parent grant proposal has two aims: (1) To identify the regions in the actomyosin complex involved in transforming the biochemical energy into directed mechanical movement and (2) to determine the structural correlates that contribute to the biochemic National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $214,414 Trans-NIH Recovery Act Research Support Williams syndrome (WS) is a neurodevelopmental condition that is caused by a hemizygous deletion of roughly 1.5-1.8 megabases, a region of chromosome band 7q11.23 that contains about 28 genes. Found in 1 in 7500-20,000 live births, persons with WS have ch
This spending item is part of a $245,038 allocation. See details
National Institutes of Health 9/07/2010
SALK INSTITUTE FOR BLOGICAL STUDIES $213,997 Trans-NIH Recovery Act Research Support This is a competitive continuation proposal to support three new aims of the project entitled Tertiary structures of potassium channel domains. This renewal proposal expands the scope and direction to a newer level by focusing on molecular working of 6 tr National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $211,147 Trans-NIH Recovery Act Research Support The long term goal of this study is to understand how biological membranes control their structural integrity, dynamical response, and physiological performance. Here we specifically study the erythrocyte membrane which has a protein network coupled to a National Institutes of Health 8/01/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $208,400 Trans-NIH Recovery Act Research Support This grant provides support to use phage evolution of a bacteriophage peptide expression library to identify peptides that can a) bind to the tympanic membrane; b) be internalized by tympanic membrane cells and 3) transit from within the tympanic membrane National Institutes of Health 7/17/2009
MCBRIDE DOOR & HARDWARE, INC. $208,049 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $207,044 Trans-NIH Recovery Act Research Support How IL-10R blockade can resolve persistent viral infections: The ARRA funded diversity supplement to R01 AI068818-01A2 has been awarded to directly support the work of Dr. Baca Jones in the von Herrath laboratory. The diversity supplement was designed to National Institutes of Health 9/17/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $205,450 Trans-NIH Recovery Act Research Support Autophagy is a process that is involved in degradation of long-lived proteins and removal of damaged organelles. Autophagy is generally thought of as a survival process that is upregulated by the cells during periods of starvations, but recent studies ha National Institutes of Health 1/28/2010
ALLIANT INTERNATIONAL UNIVERSITY $205,216 ARRA - Scholarships for Disadvantaged Students ARRA - Scholarship for Disadvantaged Students Health Resources and Services Administration 9/03/2009
Apex Pacific, Inc. $203,474 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
EPISCOPAL COMMUNITY SERVICES $202,478 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $202,155 Trans-NIH Recovery Act Research Support The Human Microbiome Project (HMP) is an NIH Roadmap program that will produce unprecedented amounts of information about the microbial communities living on and within humans. The objective of our current work is to provide a Data Analysis and Coordinati
This spending item is part of a $1,147,846 allocation. See details
National Institutes of Health 9/10/2009
SCRIPPS RESEARCH INSTITUTE, THE $201,769 Trans-NIH Recovery Act Research Support The objective of the parent grant is to identify the pheromone ligands, responding sensory neurons, and necessary neuronal circuits that mediate a defined social behavior in the mouse. Social behavior in rodents, like humans, is plastic; the age and gende National Institutes of Health 9/03/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $201,680 Trans-NIH Recovery Act Research Support The development of new technologies for the detection of copy number variation (CNV) in the human genome has had a major impact on the field of human genetics. In our ongoing efforts to characterize patterns of structrual variation in human populations, National Institutes of Health 7/14/2010
IMPERIAL BEACH COMMUNITY CLINIC $201,332 ARRA Health Center Integrated Services Development Initiative[g1] Increased demand for services at health centers: Imperial Beach Community Clinic received an ARRA Increased Demand for Services grant to increase access to primary health care for low-income and uninsured individuals in the city of Imp... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $200,000 Trans-NIH Recovery Act Research Support The overall objective of this proposal is to identify and characterize putative stem/progenitor cells in the adult pancreas. The identification of such cells would facilitate the development of a cell replacement therapy for patients with diabetes. Such t National Institutes of Health 12/07/2009
INSILICOMED, INC. $200,000 Trans-NIH Recovery Act Research Support Cardiac resynchronization therapy (CRT) is currently used extensively for treatment of congestive heart failure patients with underlying electrical conduction defects. Up to 30% of patients receiving CRT do not respond to the therapy for unknown reasons. National Institutes of Health 4/29/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $199,990 ARRA ? Equipment to Enhance Training for Health Professionals The objective of the Basic Science Methodology Laboratory Flow Cytometer Request from the University of California, San Diego is to add the necessary equipment, a BD FACSCanto II Flow cytometer, to the Basic Science Methodology Training La... Show more Health Resources and Services Administration 9/04/2010
MISSION VALLEY LANDSCAPE CO, INC $199,625 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $199,200 Trans-NIH Recovery Act Research Support Biology is increasingly becoming an information-driven science. There is an enormous demand for biologists who are trained in mathematics and computer science and can think quantitatively. However, current disciplinary graduate training programs are not d National Institutes of Health 8/03/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $198,240 Trans-NIH Recovery Act Research Support Caveolae and Anesthetic Induced Cardiac Protection. The series of experiments proposed in the ARRA supplement request will determine a novel role for Cav-3 expression in delayed preconditioning. Cav-3 may serve as a novel therapeutic target for protecting National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $197,266 Trans-NIH Recovery Act Research Support The principal aim of the previous grant was to use a combination of biophysical and computational techniques to evaluate the key features in the folding/misfolding of the 17 KD beta protein interleukin-1beta (IL-1beta). We have established that the slow f National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $196,847 Trans-NIH Recovery Act Research Support HMG-CoA reductase (HMGR) is the rate-limiting enzyme of sterol synthesis. HMGR is an integral membrane protein that undergoes regulated degradation by ER-associated degradation, or ERAD, in response to changing cellular demand for sterols. We originally s National Institutes of Health 12/21/2009
AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC. $195,997 Trans-NIH Recovery Act Research Support Grant Title: Development of protease inhibitor drugs to treat Alzheimer's disease. The ARRA grant allows a postdoctoral hire to synthesize inhibitor drugs that may lead to potential Alzheimer's disease drugs. National Institutes of Health 9/29/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $195,378 Trans-NIH Recovery Act Research Support Phage lambda Integrase (Int) is the prototype of a large family of tyrosine recombinases that performs site-specific recombination. The family includes bacterial, phage, conjugative transposon, integron and yeast plasmid enzymes. Many of these elements co National Institutes of Health 12/11/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $194,670 Trans-NIH Recovery Act Research Support Free radicals, or more specifically, reactive oxygen species (ROS), have been proposed as critical mediators of dysfunction and disease for a large number of disorders, including many in the brain related to Alzheimer's disease, accelerated aging, other n
This spending item is part of a $994,872 allocation. See details
National Institutes of Health 9/24/2009
GT LIFE SCIENCES, INC. $194,459 Trans-NIH Recovery Act Research Support Title: Model-driven Media and Process Optimization in Mammalian Cell Lines. Description: The overall goal of the project is to develop and validate a metabolic model-based platform for rational media and process optimization that significantly improves th National Institutes of Health 9/29/2009
SCRIPPS RESEARCH INSTITUTE, THE $192,897 Trans-NIH Recovery Act Research Support The award supports studies on the structure and function of human drug metabolizing enzymes that determine the clearance for many therapeutic drugs. X-ray crystallography is employed to characterize the structures of these P450 monooxygenases in complex w National Institutes of Health 9/18/2009
COUNCIL OF COMMUNITY CLINICS $191,250 ARRA Health Center Integrated Services Development Initiative[g1] The overall goal of the Connecting for Care project is to increase access to clinical data at the point of care. The CCC will build off of its existing HIT infrastructure and expertise to enhance its data warehouse and work with clinic... Show more Health Resources and Services Administration 9/14/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $191,000 Trans-NIH Recovery Act Research Support This Administrative Supplement is intended to accelerate the pace of discovery of Specific Aim 3 of the parent grant. A major focus of the parent grant was on the function of a protein, PRC1, which is important to cell cleavage. In the Specific Aim (refe National Institutes of Health 9/30/2009
MOUNTAIN HEALTH & COMMUNITY SERVICES, INC. $189,088 ARRA Health Center Integrated Services Development Initiative[g1] Increase Services to Health Centers - Mountain Health & Community Services, Inc. (MHCS) is using the funds allocated under the Increased Demand for Services initiative to hire a Family Practice physician and add new HIV and prenatal ca... Show more Health Resources and Services Administration 3/27/2009
Kone Inc. $187,739 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SCRIPPS RESEARCH INSTITUTE, THE $185,209 Trans-NIH Recovery Act Research Support The specific aims of the grant are to determine the role of visual experience in the development of the retinotectal system. We have used in VIVO 2 photon imaging and electrophysiology to address these questions and now propose to significantly enhance th National Institutes of Health 7/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $184,957 Trans-NIH Recovery Act Research Support This award is a supplement to a NIH-NCRR Science Education Partnership Award (SEPA) grant, which is designed to teach high school students about clinical research. As part of the parent grant, a partnership was formed between the University of California
This spending item is part of a $292,249 allocation. See details
National Institutes of Health 7/31/2009
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO $184,808 Trans-NIH Recovery Act Research Support A major challenge in vaccinology is that the efficacy of a vaccine can only be ascertained retrospectively, upon infection. The identification of molecular signatures induced rapidly after vaccination, which correlate with and predict, the later developme
This spending item is part of a $3,213,142 allocation. See details
National Institutes of Health 7/12/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $184,564 Trans-NIH Recovery Act Research Support In recent years, there has been a growing appreciation for the complex roles that small regulatory RNA (sRNA) can play in coordinating gene activities in both prokaryotes and eukaryotes. There exists by now a basic understanding of the molecular componen National Institutes of Health 9/08/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $184,162 Trans-NIH Recovery Act Research Support The goal of this proposal is to perform the integrated multi-disciplinary large animal studies needed to advance clinical treatment and assessment of articular cartilage injury and degeneration in the United States. Microfracture, a simple and minimally i
This spending item is part of a $1,730,845 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $184,000 Trans-NIH Recovery Act Research Support The requested supplement is to further address selected Hypotheses and Aims of the parent grant. This will be done by analyzing in more detail samples of bovine and equine SF that have already been procured and that have been, or are being, analyzed under National Institutes of Health 9/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $183,084 Trans-NIH Recovery Act Research Support This program will train Ph.D. students at The Scripps Research Institute in the principles of evolutionary mechanisms in biological systems, and in the application of those principles in the laboratory to problems of biomedical science. ARRA funding will National Institutes of Health 8/03/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $180,224 Trans-NIH Recovery Act Research Support The goal of this proposal is to perform the integrated multi-disciplinary large animal studies needed to advance clinical treatment and assessment of articular cartilage injury and degeneration in the United States. Microfracture, a simple and minimally i
This spending item is part of a $1,730,845 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $175,049 Trans-NIH Recovery Act Research Support Chronic viral infections afflict more than 500 million people worldwide. Loss of T cell function has been noticed for long time during persistent viral infections but the underlying factors are not completely understood. By using in vivo chronic lymphocyt National Institutes of Health 9/11/2009
ZACHARON PHARMACEUTICALS, INC. $175,000 Trans-NIH Recovery Act Research Support The purpose of the supplement is to accelarate our anticancer compounds toward clinical testing. These novel compounds are the first pharmacologically relevant inhibtiors of gangliosides; a class of lipid-linked glycans known to be key melanoma and neur National Institutes of Health 9/09/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $174,559 Trans-NIH Recovery Act Research Support The purpose of this grant is to study the function of the annealing helicase HARP in Drosophila melanogaster. In research funded by the parental grant (NIH R01 GM058272), we discovered that human HARP protein has a novel reverse (annealing) helicase activ National Institutes of Health 7/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $174,290 Trans-NIH Recovery Act Research Support The goal of this project is use rat lines selected for high and low stress responses to investigate the neurobiological bases of individual differences in vulnerability to stress by gene espression profiling coupled with a systems biology gene network ana National Institutes of Health 1/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $172,529 Trans-NIH Recovery Act Research Support This Administrative Supplement meets the overarching objectives of the ARRA Administrative Supplement by accelerating the tempo and enhancing the parent R01 project ?Development of the Functional Neural Systems for Face Expertise? (R01 HD060595; PI: Frank National Institutes of Health 7/27/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $171,728 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Understanding the cellular and molecular mechanisms of hazardous chemicals in our environment is a critical national objective. The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) was est
This spending item is part of a $231,728 allocation. See details
National Institutes of Health 9/10/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $171,423 Trans-NIH Recovery Act Research Support The goal of the proposed research is to understand at a molecular level, how chemokines and their receptors control cellular migration and activation. These proteins are part of a surveillance system that protects the host from pathogens, abnormal cell gr National Institutes of Health 7/06/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $170,636 Trans-NIH Recovery Act Research Support Molecular Imaging of G-Protein Coupled Receptors for Drug Development Supplemental support is requested that will enable the research on structural studies of G-protein-coupled receptors to be accelerated and improved. The support for a postdoc National Institutes of Health 8/11/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $169,332 Trans-NIH Recovery Act Research Support Transport systems provide essential functions for all living cells. Their importance to medicine cannot be overemphasized as (1) they provide a basis for multidrug resistance in pathogenic bacteria, fungi and protozoans as well as in tumor cells, (2) they National Institutes of Health 8/11/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $168,845 Trans-NIH Recovery Act Research Support This fund is an ARRA diversity administrative supplement to Parent Fund #54862C entitled, 'M-RISP at SDSU.' This supplemental funding will provide a two-year full-time research employment opportunity for a postdoctoral student. The candidate will gain va National Institutes of Health 7/21/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $166,962 Trans-NIH Recovery Act Research Support The goal of the SDSU Bridges program is to train 18 students a year from the three partnering colleges to complete their bachelors degree training, despite high GPA requirements for transfer and entry into the impacted biology major at SDSU. The outcome o National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $166,752 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The low-affinity Na+/dicarboxylate cotransporter NaDC1 is found on the apical membrane of the renal proximal tubular epithelium, where it plays an important role in the reabsorption of citric acid cycle intermediates, National Institutes of Health 9/29/2009
SAN DIEGO UNIFIED SCHOOL DISTRICT $166,404 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $166,157 Trans-NIH Recovery Act Research Support Protein synthesis is a fundamental process in all living organisms. During the elongation phase of protein synthesis, the ribosome accurately selects the aminoacyl-tRNA corresponding to the mRNA codon. The long-term objective of this proposal is to study National Institutes of Health 9/08/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $165,779 Trans-NIH Recovery Act Research Support Effective prevention strategies for HIV are critically needed, and an effective HIV vaccine is the best long-range hope to dramatically reduce the rate of new HIV infections. To this goal, our current understanding of the biology and epidemiology of HIV t National Institutes of Health 9/11/2009
LUDWIG INSTITUTE FOR CANCER RESEARCH $165,600 Trans-NIH Recovery Act Research Support Centrioles perform two critical functions in eukaryotes: (1) they direct the accumulation of microtubule nucleating/anchoring material to form centrosomes that play a critical role during cell division, and (2) they serve as basal bodies that direct the f National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $165,554 Trans-NIH Recovery Act Research Support Mitogen activated protein kinases (MAPKs) are serine/threonine kinases that mediate signal transduction and orchestrate cellular responses to environmental stress. In mammalian cells, three principle MARK pathways have been identified, including extracell National Institutes of Health 6/28/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $165,402 Trans-NIH Recovery Act Research Support Comparisons of the genomes from humans and lower organisms reveal that the complexity in humans is achieved not by a dramatic increase in the number of genes but by alternative splicing events that stitch together different portions of genes to generate d National Institutes of Health 9/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $165,157 Trans-NIH Recovery Act Research Support This is a proposal for an Administrative Supplement for parent grant NS012601-34 entitled Signal Transduction at Neuronal Nicotinic Synapses?. It examines the interactions of nicotinic and GABAergic signaling pathways, the effects of nicotinic input on s National Institutes of Health 8/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $164,827 Trans-NIH Recovery Act Research Support Medical decision support tools are increasingly available on the Internet and are being used by lay persons as well as health care professionals. The goal of some of these tools is to provide an individualized prediction of future health care related even National Institutes of Health 9/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $164,827 Trans-NIH Recovery Act Research Support Medical decision support tools are increasingly available on the Internet and are being used by lay persons as well as health care professionals. The goal of some of these tools is to provide an individualized prediction of future health care related even National Institutes of Health 9/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $164,501 Trans-NIH Recovery Act Research Support Development of new chemical transformations useful for drug discovery and for interrogation of biological systems is the main goal of this project. Olefins provide a most efficient entry to organic compounds with diverse and controllable functionality. T National Institutes of Health 12/31/2009
SCRIPPS RESEARCH INSTITUTE, THE $163,243 Trans-NIH Recovery Act Research Support The overall goal of this project is to study translation initiation in eukaryotes. The goal of the work funded by this award is to investigate the scope and physiological relevance of mRNA-rRNA base pairing interactions during translation initiation by us National Institutes of Health 12/25/2009
LUDWIG INSTITUTE FOR CANCER $162,658 Trans-NIH Recovery Act Research Support The essential function of mitosis is the delivery of a complete set of chromosomes to each daughter cell. This requires attachment of spindle microtubules to kinetochores, specialized structures formed at centromeres. Kinetochores are more than just struc National Institutes of Health 9/30/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $161,875 Trans-NIH Recovery Act Research Support This is an administrative ARRA supplement. The parent grant for this supplement is part of the Collaborative Initative on Fetal Alcohol Spectrum Disorders (CIFASD). The primary aim of the parent project is to determine whether a neurobehavioral phenotyp
This spending item is part of a $305,875 allocation. See details
National Institutes of Health 7/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $161,140 ARRA ? Equipment to Enhance Training for Health Professionals All the requested equipment has been purchased by the UCSD RMTL: (3) Recording spectrophotometers; (2) High Speed Refrigerated Centrifuge/2-rotors; (1) Refrigerator: 24.4 cu ft isotemp -86 -?C Ultralow temperature; (1) Freeze-Dry Maniford ... Show more
This spending item is part of a $228,291 allocation. See details
Health Resources and Services Administration 9/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $159,408 Trans-NIH Recovery Act Research Support The proposed research will accelerate the development of new classes of therapeutics for CNS and eye diseases, as identified in the parent project (EY018479). Measured against a quarterly progress schedule, this concerted and dedicated effort by 1 new res National Institutes of Health 1/01/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $159,268 Trans-NIH Recovery Act Research Support Cardiovascular disease remains the leading cause of death in the United States and vascular calcification and diabetes are both independent risk factors for incident cardiovascular disease. Fetuin-A is a hepatic secretory protein found in high concentrati National Institutes of Health 7/31/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $158,561 Trans-NIH Recovery Act Research Support This ARRA-funded award is a research supplement to support two students: pre-doctoral trainee Ms. Nafissatou Cisse and post-doctoral student Ms. Claudia Carrizosa. They will be mentored by leaders within the research community -- including the principal National Institutes of Health 9/29/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $157,724 Trans-NIH Recovery Act Research Support This project will focus on the question of whether Bax and Bid are recruited to mitochondria before or after the MPTP opens. We hypothesize that Bid recruitment follows MPTP opening because of exposure of cardiolipin. Accordingly, we will prepare recombin National Institutes of Health 7/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $157,504 Trans-NIH Recovery Act Research Support The 4DB Center's potential impact is on two fronts, the basic research ability to conduct physical sciences experiments on cancer patient samples in a meaningful way and to generate the force and time journey of cancer cells during the metastatic phase. T
This spending item is part of a $3,878,972 allocation. See details
National Institutes of Health 9/29/2009
SOUTHERN INDIAN HEALTH COUNCIL $155,374 ARRA - IHS Tribal Agreements Concrete/Asphalt Paving Parking Area Indian Health Service 10/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,525 Trans-NIH Recovery Act Research Support Despite significant advances in our understanding of how trinucleotide repeats cause disease, mechanisms underlying their unique property of genetic instability remain ill-defined. Of all CAG/polyglutamine diseases, spinocerebellar ataxia type 7 (SCA7) di National Institutes of Health 11/26/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,500 Trans-NIH Recovery Act Research Support The pituitary gland is an endocrine organ that secretes hormones to control various vital processes throughout the body, including growth during childhood, the stress response, sexuality, reproduction, metabolic homeostasis, and lactation. It dynamically National Institutes of Health 4/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,500 Trans-NIH Recovery Act Research Support Tobacco smoke is the single most preventable risk of cancer and is responsible for lung cancer being the highest in incidence worldwide. Research on the association between tobacco and cancer relied on questionnaire data for tobacco exposure assessment wh National Institutes of Health 7/13/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,444 Trans-NIH Recovery Act Research Support PROJECT SUMMARY: The parent grant, R01GM0578089, provides for continued efforts in the expansion of the scope and depth of computational models of E. coli. Crucial to this area of work are high-throughput experiments which test model predictions and lea National Institutes of Health 12/21/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,288 Trans-NIH Recovery Act Research Support Our requests for supplemental funding will allow us to accelerate our progress in several areas, and each of these requests are driven by technological advances in parallel with an enhanced understanding of the increasingly complex signaling networks that National Institutes of Health 12/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $154,166 Trans-NIH Recovery Act Research Support The overall goal of our research is to elucidate the pathogenesis of primary open-angle glaucoma (POAG) making it possible to implement effective screening and prevention strategies and to develop novel therapies. The primary aim of this proposal is to id
This spending item is part of a $503,839 allocation. See details
National Institutes of Health 6/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $153,687 Trans-NIH Recovery Act Research Support We are requesting an Administrative Supplement to our Grant ?Neurotoxins from Marine Algae and Cyanobacteria? (NS053398) so as to increase the pace and tempo of the research on aims previously approved in peer review. The broad, long term objectives of National Institutes of Health 8/10/2009
ST. VINCENT DE PAUL VILLAGE, INC. $152,674 ARRA Health Center Integrated Services Development Initiative[g1] San Diego's Regional Task Force on the Homeless reports the number of homeless has increased 9% since last count and the proportion of homeless living on the street increased from 44% to 51%. As the largest provider of homeless service... Show more Health Resources and Services Administration 3/27/2009
SIALIX, INC. $152,526 Trans-NIH Recovery Act Research Support Possible development of diagnostic products for Rheumatoid Arthritis. Specifically, these diagnostics will identify patients who have disease exacerbations due to Neu5Gc accumulation in joints from dietary sources combined with certain anitNeu5Gc antibodi National Institutes of Health 9/25/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $150,410 Trans-NIH Recovery Act Research Support Visual perception is mediated by complex interactions amongst neurons in the retina, visual cortex, and subcortical brain structures. The importance of vision to humans and other primates is reflected in the enormous percentage of cerebral cortex devoted National Institutes of Health 1/29/2010
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $146,350 Trans-NIH Recovery Act Research Support This supplement awarded under the American Recovery and Reinvestment Act will fund the purchase of an ECL imager to carry out all the western blotting required in this project. It will also allow for a postdoctoral fellow to remain supplied and funded on National Institutes of Health 6/28/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $146,322 Trans-NIH Recovery Act Research Support The 3D-Structure of the Immunoglobulin Heavy Chain Locus In recent studies it has become clear that the CTCF proteins act as a ?weaver of the genome?. Specifically, the CTCF proteins functions as anchors of loops that organize the chromatin fiber into ro National Institutes of Health 8/09/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $146,062 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The objectives and aims of this application are for San Diego to become the first western United States clinical site in the Pelvic Floor Disorders Network (PFDN). The San Diego Clinical Site is a collaboration of thr
This spending item is part of a $252,370 allocation. See details
National Institutes of Health 9/29/2009
ALLIANT INTERNATIONAL UNIVERSITY $144,096 ARRA - Scholarships for Disadvantaged Students Scholarship for Disadvantaged students to promote completion of their educational program and work within the high need, low income clinics. Health Resources and Services Administration 6/14/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $142,919 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This proposal is for a 5 year renewal (years 16-20) of the Alzheimer's Disease Cooperative Study (ADCS). This consortium of 34 members' sites and 46-56 participating sites is proposing both continued instrument develop National Institutes of Health 9/11/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $142,050 Trans-NIH Recovery Act Research Support The overarching goal of this program project is to build bridges across disciplines, linking higher cognitive functions to their underlying neurobiological bases and their molecular genetic underpinnings using a specific genetic disorder, Williams syndrom National Institutes of Health 9/17/2009
LA JOLLA INFECTIOUS DISEASE INSTITUTE $141,934 Trans-NIH Recovery Act Research Support In contrast to the well studied role of intrinsic factors in tumorigenesis, knowledge regarding the mechanism(s) whereby extrinsic factors, such as the stromal/matrix microenvironment, influence an initiated cell with permanent genetic alterations to tran
This spending item is part of a $591,082 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $140,835 ARRA - Scholarships for Disadvantaged Students ARRA - Scholarships for Disadvantaged Students Health Resources and Services Administration 9/03/2009
SCRIPPS HEALTH $138,970 Trans-NIH Recovery Act Research Support The 4DB Center's potential impact is on two fronts, the basic research ability to conduct physical sciences experiments on cancer patient samples in a meaningful way and to generate the force and time journey of cancer cells during the metastatic phase. T
This spending item is part of a $3,878,972 allocation. See details
National Institutes of Health 9/29/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $137,388 Trans-NIH Recovery Act Research Support The parent grant of this supplement application targets the development of computational tools for determining the structures of large protein complexes by combining atomic models of components with electron microscopy reconstructions in the resolution ra National Institutes of Health 2/24/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $135,714 Trans-NIH Recovery Act Research Support CD-HIT is a computer program for clustering and comparing large sets of protein or nucleotide sequences. It helps to significantly reduce the computational and manual efforts in various sequence analysis tasks and aids in understanding the data structure National Institutes of Health 8/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $134,000 Trans-NIH Recovery Act Research Support The UCSD Digestive Diseases Research Development Center was awarded an ARRA supplement of $134,000. The Center has purchased, consistent with the proposal, a Cell ZScope (Biometrology), a Wire Monograph System (DMT), an AD Instruments ML870/P PowerLab wit National Institutes of Health 7/21/2009
ELI WIENER-AVNEAR $132,100 Trans-NIH Recovery Act Research Support The objective of the recovery award is to allow LEEOAT Company to develop, design, theoretical model, fabricate and test our innovative volumetric imagers, to support noninvasive real-time guiding of medical catheters during clinical therapeutic procedure National Institutes of Health 8/10/2009
CHILDREN OF THE RAINBOW HEAD START LLC $131,560 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $131,325 Trans-NIH Recovery Act Research Support Many commonly prescribed anionic drugs (eg. antibiotics, diuretics, ACE inhibitors, NSAIDs) as well as disease-associated metabolites are organic anions that are excreted as a result of transport by the proximal tubule of the kidney. The rate limiting gen National Institutes of Health 7/09/2010
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $130,890 Trans-NIH Recovery Act Research Support A major goal of the CSUSM MARC Phase II Curriculum Improvement grant is to integrate quantitative and computational knowledge and skills throughout the entire undergraduate biology curriculum. Calculus is potentially an important tool for many science co National Institutes of Health 7/14/2009
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $130,890 Trans-NIH Recovery Act Research Support A major goal of the CSUSM MARC Phase II Curriculum Improvement grant is to integrate quantitative and computational knowledge and skills throughout the entire undergraduate biology curriculum. Calculus is potentially an important tool for many science co National Institutes of Health 7/14/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $130,368 Trans-NIH Recovery Act Research Support The joint doctoral program (JDP) in Public Health offered by SDSU's Graduate School of Public Health and the UCSD's School of Medicine is an ideal setting for training future investigators who may bridge the two disciplines: behavioral and biological/biom National Institutes of Health 8/13/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $130,030 Trans-NIH Recovery Act Research Support The goal of the Center for Reproductive Science and Medicine at UCSD is to develop understanding of the mechanisms that govern normal and disordered function of the hypothalamic-pituitary-ovarian axis. This application represents our renewal for years 29- National Institutes of Health 8/26/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $129,090 Trans-NIH Recovery Act Research Support This ARRA supplement under the parent U01 grant was funded to expand the original parent U01 scope of work. Based on our earlier meetings with NIMH and the US Army, the focus of this study was expanded in five ways: (i) the range of outcomes assessed; (i
This spending item is part of a $10,000,000 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $128,779 Trans-NIH Recovery Act Research Support TITLE: Mechanisms of Tissue Morphogenesis in C. elegans DESCRIPTION/PURPOSE: This supplemental project will develop and implement new software for automatic cell identificaiton and tracking in C. elegans embryos. Work from the parent project has ca National Institutes of Health 9/15/2009
SCRIPPS RESEARCH INSTITUTE, THE $127,463 Trans-NIH Recovery Act Research Support The nuclear factor kappa B (NF-kB) family of transcription factors controls inter- and intracellular signaling, cellular stress responses, cell growth, survival, and apoptosis. In resting cells, NF-kB dimers with transcription activation potential are seq National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $126,586 Trans-NIH Recovery Act Research Support Data for this study comes from CNICS, which is a multi-center collaborative project to create and maintain the CFAR Network of Integrated Clinical Systems (CNICS), a clinical cohort for longitudinal studies in HIV.The CNICS Network provides anonymized dem
This spending item is part of a $138,211 allocation. See details
National Institutes of Health 9/07/2010
SCRIPPS RESEARCH INSTITUTE, THE $125,853 Trans-NIH Recovery Act Research Support Methamphetamine (METH) use is of major public health concern given its prevalence among individuals who are HIV infected and its association with HIV transmission risk behaviors, particularly high-risk sexual behavior. METH use strongly alters brain dopa
This spending item is part of a $1,067,183 allocation. See details
National Institutes of Health 8/14/2009
SALK INSTITUTE FOR BLOGICAL STUDIES $125,800 Trans-NIH Recovery Act Research Support During fasting, elevations in circulating pancreatic glucagon promote hepatic glucose output through induction of the gluconeogenic program by the CREB coactivator TORC2. Sequestered in the cytoplasm during feeding, TORC2 translocates to the nucleus in re National Institutes of Health 4/09/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $125,568 Trans-NIH Recovery Act Research Support This supplement will advance our scientific discovery by accelerating data analyses on a funded-study involving approximately 620 adolescents, assessed in infancy, 3 to 5 years and 10 years as part of a NIH-supported cohort study of the behavioral and dev National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $124,428 ARRA - Immunization Childrens Health Systems Inc., the foundation established by leadership of the American Academy of Pediatrics- California, has been awarded ARRA funding to develop vaccine safety communication materials and curriculum for medical residents. Targeted train
This spending item is part of a $370,506 allocation. See details
Centers for Disease Control and Prevention 9/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $123,435 Trans-NIH Recovery Act Research Support The project is directed toward the development of technology for cloning mice from fibroblasts. This will permit us to recover mice that die as a result of conditionally lethal phenotypes, such as hypersensitivity to lPS. The deliverables are cloned mice National Institutes of Health 8/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $123,319 Trans-NIH Recovery Act Research Support Our current understanding of cutaneous innate immunity states that the skin initially protects against infection by establishing physical and chemical barriers to microbes. These include the stratum corneum, antimicrobial peptides, reactive oxygen species National Institutes of Health 8/14/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $122,618 Trans-NIH Recovery Act Research Support The long-term goal of this project is to elucidate the mechanisms by which erbB2 regulates mammalian development. The erbB signaling network has been established as a key regulator of multiple developmental and physiological processes, including synaptic National Institutes of Health 6/22/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $120,491 Trans-NIH Recovery Act Research Support This supplemental application for the UAB-UCSD O'Brien Core Center for Acute Kidney Injury (AKI)(1P30 DK079337) in response to NIDDK FY2009 Program for Administrative Supplements Utilizing Recovery Act Fund (NOT-OD-09-056) is designed to facilitate new an
This spending item is part of a $363,337 allocation. See details
National Institutes of Health 8/10/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $120,488 Trans-NIH Recovery Act Research Support The prospect of prophylactov treatment of a large number of people with small pox antiviral agents raises the possibility of a significant degree of toxicity to the kidney and other organs. Since the basolateral Oast and other apical multispecific transpo National Institutes of Health 9/29/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $119,956 Trans-NIH Recovery Act Research Support Our parent R01 grant (5R01CA109345-05), which will end on June 30, 2009, proposes to investigate the molecular mechanism by which retinoid X receptor-alpha (RXR?) acts in the cytoplasm in response to 15-Deoxy-?12,14-prostaglandin J2 (15d-PGJ2) and analogs National Institutes of Health 9/15/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $119,217 Trans-NIH Recovery Act Research Support The aims of the supplement are to support the goals of the parent grant by 1) increasing the efficiency of creating transgenic lines of Drosophila melanogaster expressing myosin heavy chain, 2) improving the expression of levels of transgenic myosin genes National Institutes of Health 1/21/2010
SCRIPPS RESEARCH INSTITUTE, THE $119,136 Trans-NIH Recovery Act Research Support The overall goal of this project is to provide a novel representation of the flexibility of biological macromolecules that is computationally tractable and usable in simulations such as automated docking. The approach is based on the development of a hier National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $119,030 Trans-NIH Recovery Act Research Support A complex interaction of different processes play a critical role in the development of hematopoietic lineages, and among the most important are the controls of hematopoietic stem cell (HSC) commitment. Understanding this process is critical to understand
This spending item is part of a $250,000 allocation. See details
National Institutes of Health 9/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $118,621 Trans-NIH Recovery Act Research Support The VETSA Longitudinal Twin Study of Cognition and Aging is a unique project that provides a comprehensive prospective examination of genetic and environmental influences on cognitive and brain aging with extensive data from neurocognitive, health/medical National Institutes of Health 9/24/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $118,250 Trans-NIH Recovery Act Research Support The overall goal of the UCLA Center for Gene Environment Studies in Parkinson Disease (UCLA CGEP), one of 3 CNS supported by NIEHS, is to determine the mechanisms by which pesticides that have been shown in epidemiological studies of the Center to increas
This spending item is part of a $195,250 allocation. See details
National Institutes of Health 7/16/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $118,206 Trans-NIH Recovery Act Research Support X-linked spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) is an inherited neuromuscular disorder characterized by lower motor neuron degeneration. SBMA is caused by CAG/polyglutamine (polyQ) repeat expansions in the human androgen receptor (A National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $116,538 Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-GM-101: Anesthesiology Clinical Pharmacology Sepsis Trauma, Burn, and Peri-operative Injury Wound Healing. Traumatic brain injury
This spending item is part of a $980,750 allocation. See details
National Institutes of Health 9/30/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $116,232 Trans-NIH Recovery Act Research Support Our 'metagenome' is a composite of H. sapiens genes and genes present in the genomes of the trillions of microbes that colonize our adult bodies. 'Our' microbial genomes (microbiome) encode metabolic functions we have not had to evolve on our own, but rem
This spending item is part of a $300,001 allocation. See details
National Institutes of Health 9/18/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $116,176 Trans-NIH Recovery Act Research Support The administrative supplemental studies are in support of the active NIH research grant, 5 R01 AG026727 ('Dendritic cells of the aged'). The goal of the studies is to elucidate the role of alveolar macrophages in the increased inflammatory milieu in the National Institutes of Health 9/18/2009
ZOOLOGICAL SOCIETY OF SAN DIEGO $115,212 Trans-NIH Recovery Act Research Support Most behavioral traits have complex bases and are the result of interactions between multiple genes and/or environments. Therefore, advancing our knowledge of human behavior will require an understanding of the genetic, epigenetic, and environmental bases
This spending item is part of a $629,968 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $114,633 Trans-NIH Recovery Act Research Support Malaria continues to expand as a major public health threat throughout the world. The spread of drug resistant malaria and the lack of an effective vaccine make alternative and complementary approaches to malaria control increasingly important. The overal National Institutes of Health 8/03/2009
ALPHA KAPPA ALPHA HEADSTART PROGRAM INC $114,033 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
GENE THERAPY SYSTEMS, INC. $113,728 The Parent award is entitled Screening Complete TB Proteome for Protective Antigens. As part of this research, we have identified a number of candidate antigens that would also serve as a diagnostic test for TB. One concern going forward is whether our National Institutes of Health 4/26/2010
GENE THERAPY SYSTEMS, INC. $113,728 Trans-NIH Recovery Act Research Support The Parent award is entitled Screening Complete TB Proteome for Protective Antigens. As part of this research, we have identified a number of candidate antigens that would also serve as a diagnostic test for TB. One concern going forward is whether our National Institutes of Health 4/26/2010
Acoustics I Heartland $113,478 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $111,377 Trans-NIH Recovery Act Research Support Nonhuman primates (NHPs) provide powerful animal models for exploring the pathogenesis of infectious and noninfectious diseases, and for testing of new therapies and vaccines that cannot be evaluated in rodents. Over the past decade, the number of NIH gra
This spending item is part of a $347,988 allocation. See details
National Institutes of Health 9/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $110,890 Trans-NIH Recovery Act Research Support The project (ROI DK075718) is designed to evaluate the role of innate immunity in renal ischemia reperfusion injury and is focused primarily on the role of innate immune activation in acute kidney injury. Three aims were proposed in the original grant to National Institutes of Health 8/31/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $109,997 Trans-NIH Recovery Act Research Support This ARRA administrative supplement will fund pre-clinical work that will lead up to a human clinical trial for HIV-associated cognitive decline testing the peptide cytokines erythropoietin in conjunction with insulin-like growth factor-I. We have previo National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $109,877 Trans-NIH Recovery Act Research Support Mutations in rhodopsin are the most common causes of hereditary forms of Retinitis Pigmentosa (RP). Many of these mutations lead to misfolding of rhodopsin protein and retention within the endoplasmic reticulum (ER). The molecular pathways that link rhodo National Institutes of Health 8/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $109,017 Trans-NIH Recovery Act Research Support The Kissi gene encodes proteins called kisspeptins, v^rhich bind to the G-protein coupled receptor GPR54. Kissl is expressed in discrete brain regions that regulate reproductioa and in mammals, induding humans, kisspeptins stimulate the secretion of gonad National Institutes of Health 8/18/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $108,150 Trans-NIH Recovery Act Research Support This supplement's aim is to increase our understanding of the mechanism by which airway inflammation may contribute to airway remodeling in asthma. Studies will focus on the role of the airway epithelium and T cells in contributing to airway remodeling u
This spending item is part of a $344,400 allocation. See details
National Institutes of Health 7/26/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $108,000 Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes symmetric polyarthritis and joint destruction. Considerable work in the pathogenesis of RA has implicated multiple signaling pathways that regulate the production of pro-inflammatory National Institutes of Health 9/18/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $108,000 Trans-NIH Recovery Act Research Support This project builds upon our Fogarty Framework Partnership between the University of California San Diego (UCSD) and San Diego State University (SDSU) (R25TW0075) to develop a Center of Expertise in Migration and Health (COEMH) in collaboration with other National Institutes of Health 9/03/2009
SCRIPPS RESEARCH INSTITUTE, THE $107,673 Trans-NIH Recovery Act Research Support The goal of this project is to determine the catalytic mechanism of the glmS ribozyme, which is an important RNA enzyme that regulates bacterial metabolism. The approach is to use 8-azapurine fluorescence to monitor the protonation states of G33, an essen National Institutes of Health 1/21/2010
Helix High School $107,292 Trans-NIH Recovery Act Research Support This award is a supplement to a NIH-NCRR Science Education Partnership Award (SEPA) grant, which is designed to teach high school students about clinical research. As part of the parent grant, a partnership was formed between the University of California
This spending item is part of a $292,249 allocation. See details
National Institutes of Health 7/31/2009
SHARP HEALTHCARE FOUNDATION $106,300 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $106,033 Trans-NIH Recovery Act Research Support This administrative supplement will satisfy the requirements of the program in that the additional personnel and scientific activities performed accelerates the tempo of scientific research in achieving specific aims and advance the objective of the Recov National Institutes of Health 9/21/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $104,260 Trans-NIH Recovery Act Research Support The overall goal of the project is to characterize the structures and interactions of the BCL-2 family proteins, the principal regulators of the mitochondrion-dependent pathway for programmed cell death or apoptosis. Their opposing pro- or anti-apoptotic National Institutes of Health 7/17/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $103,640 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This is the third competitive renewal of our Program Project Grant. We have modified the name to reflect the refinement in focus, Antibody Targeted Radiation and Immunotherapy for the Treatment of Solid Tumors. There a
This spending item is part of a $1,999,788 allocation. See details
National Institutes of Health 9/29/2010
WOLFPACK, INC. $102,450 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $102,208 Trans-NIH Recovery Act Research Support Influenza A nonstructural gene, NS1, promotes infection and viral maturation by suppressing the host immune system. Our goal is to explore cellular targets of NS1 and determine how they are affected during infection. In addition, since current treatments National Institutes of Health 6/03/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $102,023 Trans-NIH Recovery Act Research Support The long-range objective of this proposal is to gain insight into the mechanism of heparan sulfate proteoglycan assembly and its regulation. Heparan sulfate proteoglycans participate in a variety of physiological processes by binding, activation or immobi National Institutes of Health 1/29/2010
SCRIPPS RESEARCH INSTITUTE, THE $101,797 Trans-NIH Recovery Act Research Support The overall purpose of the award is to determine whether pharmacological Inositol (1 ,4,5) Trisphosphate 3-kinase B (ItpkB)-inhibition could provide an avenue towards cost effectively reducing detrimental T cell function and cytokine storm in swine influe National Institutes of Health 8/13/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,491 Trans-NIH Recovery Act Research Support The central theme of the Program Project Is focused on mechanisms that determine innate and acquired immune responses in the intestinal mucosa to enteric microbes and microbial products, and the consequent mucosal protective immune and inflammatory respon National Institutes of Health 2/18/2010
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $100,328 Trans-NIH Recovery Act Research Support Obesity is now at epidemic proportions and is a risk factor for several debilitating illnesses such as Type II diabetes, hypertension and cardiovascular disease. The beta-adrenergic receptors (beta-ARs) are key regulators of adipose tissue metabolism to c National Institutes of Health 7/23/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,057 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The Specialized Program of Translational Research in Acute Stroke (SPOTRIAS) at the University of California San Diego (UCSD) Stroke Center currently applies the resources of 4 Cores to conduct 3 interrelated clinical
This spending item is part of a $140,237 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support The long-term goal of this research-training proposal is to understand how transcriptional feedback circuits regulate phenotype in mammalian systems. The specific goal is to understand how the transcriptional circuitry of human cytomegalovirus (CMV), a he National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support Mitochondria are membrane-bound organelle found in animal and plant cells, providing the power source for cellular activities. Disorders of mitochondrial function lead to a number of diseases, such as obesity and diabetes. Reversible modification of prote National Institutes of Health 3/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support We propose here to focus on the parent Grant Specific Aim obtaining broader, ?genome-wide? insight into the three dimensional regulation of nuclear architecture. Specifically, we are in a position to explore new approaches to several unexpected aspects of National Institutes of Health 3/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support Diabetes is a major health care problem that has reached crisis proportions. The disease accounts for >14% of total national health care expenditures in the US, untold losses of precious human resources, and new therapies are urgently needed. We are devel National Institutes of Health 3/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support Central goal is to elucidate the role of a MAP3K known as MLK3 (mixed lineage kinase-3) in inducing beta cell death. The rationale behind our studies is the demonstration that both cytokines and lipids, like ceramide, act as specific agonists of MLK3, su National Institutes of Health 2/01/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $100,000 Trans-NIH Recovery Act Research Support The purpose of this proposal is to refine magnetic resonance (MR) imaging and spectroscopy to provide a comprehensive non-invasive assessment of patients with non-alcoholic fatty liver disease (NAFLD). The specific aims are to implement and develop MR met National Institutes of Health 2/16/2010
INDIAN HEALTH COUNCIL $100,000 ARRA - IHS Tribal Agreements The funded amount of $100,000 is to develop interfaces that will enable non-Resource and Patient Management System users to electronically report data to the Indian Health Service. Indian Health Service 8/16/2010
RESCUE SOCIAL CHANGE GROUP, LLC $100,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work MEDIA Objective 1: By December 2011, develop hard-hitting counter marketing media campaign to target high risk youth. G?? Secure media contractor G?? Select youth input and youth-driven products Anticipated Outcomes G?? Reduc... Show more
This spending item is part of a $7,593,110 allocation. See details
Centers for Disease Control and Prevention 3/18/2010
ARRAYOMICS INC $99,999 Trans-NIH Recovery Act Research Support High Multiplexing Liquid Array Assay Platform The aim of this project is to expand the capabilities of a novel liquid array platform, based on Encoded Sortable Particle (ESP) technology to make it cost and performance compatible with high multiplex assays National Institutes of Health 7/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,999 Trans-NIH Recovery Act Research Support Hematopoietic stem cells (HSCs) both self-renew and generate all blood cell lineages for life. HSCs are born in the embryo, but relatively little is known regarding their ontogeny and early function. This is due, in large part, to these events occurring i National Institutes of Health 1/18/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,960 Trans-NIH Recovery Act Research Support The kidney collecting system arises through branching morphogenesis of the ureteric bud (UB), a process that we have been able to replicate in vitro by culturing the isolated UB in the presence of a metanephric mesenchyme cell conditioned medium. Our puri National Institutes of Health 12/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,958 Trans-NIH Recovery Act Research Support Gene regulatory networks lay at the foundation of biological function and are responsible for driving the diverse cellular tasks required to sustain life. Developing a comprehensive description of cellular function in healthy and diseased states will req National Institutes of Health 4/16/2010
SCRIPPS RESEARCH INSTITUTE, THE $99,955 Trans-NIH Recovery Act Research Support Source MdX has built an integrated molecular medicine tracking system, called TheraTrax?, to provide high-precision tracking of disease and response to therapy. The Source TheraTrax? system is based on high-precision measurements of gene expression, a gro
This spending item is part of a $215,000 allocation. See details
National Institutes of Health 6/10/2010
SCRIPPS RESEARCH INSTITUTE, THE $99,927 Trans-NIH Recovery Act Research Support The overall purpose of the administrative supplement is to test the hypothesis that type 2 Ucns and CRF2 receptors are part of the integrated homeostatic system that normally regulates energy balance to oppose excess weight gain. To expedite this project, National Institutes of Health 2/03/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,900 Trans-NIH Recovery Act Research Support In our parent grant, we propose a unique academic-industrial partnership between investigators at the University of California San Diego (Academic Partner) and AntiCancer, Inc. (Industrial Partner) to develop and validate color-coded fluorescent imaging s National Institutes of Health 8/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,870 Trans-NIH Recovery Act Research Support We have made excellent progress with the parent grant project, elucidating the identity of Mtm pathway core components that regulate and respond to specific phosphoinositides important for cellular remodeling in vivo. Our ongoing research continues to pur National Institutes of Health 1/08/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,839 Trans-NIH Recovery Act Research Support This is an administrative supplement request in support of NCI award R37-CA44848-23. This application requests funds for the purchase of a new large-scale autoclave to replace an old unit that is barely functional. The new unit will allow the large-sca National Institutes of Health 7/08/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,445 Trans-NIH Recovery Act Research Support This grant provided summer research experiences for two teachers, one graduate student, and two undergraduate students in health-related scientific research. Project NCE (no Cost Extension)ended 11/30/10. National Institutes of Health 7/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $99,233 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This proposal aims to improve and exploit fluorescent proteins (FPs); quantum dots (QDs), methods for delivery of nanoparticles such as QDs to cytoplasmic targets, and techniques for correlative optical/electron micros National Institutes of Health 9/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $99,000 Trans-NIH Recovery Act Research Support Glucagon initiates the gluconeogenic program in hepatocytes by activating the cAMP signaling pathway, while insulin inhibits hepatic gluconeogenesis. A key regulator of this process is TORC2 (also known as CRTC2), which functions as a molecular switch in National Institutes of Health 2/19/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $98,726 Trans-NIH Recovery Act Research Support SUMMARY: Natural Inhibitors of Carcinogenesis (P01 CA48122) is uniquely designed discovery new cancer chemopreventive agents from deep ocean sediment-derived microorganisms, and promote these discoveries to the level of structurally- and mechanistically-
This spending item is part of a $477,847 allocation. See details
National Institutes of Health 8/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $98,000 Trans-NIH Recovery Act Research Support Whether it be the aroma of our morning coffee or the scent of a lover, the sense of smell is a critical feature of daily life. The long-term objective of our research is to understand how olfactory information is processed in the mammalian brain. To addre National Institutes of Health 7/17/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES $97,715 Trans-NIH Recovery Act Research Support Stem cells provide for the maintenance and regeneration of organs and tissues throughout life, and loss of the regenerative capacity of tissues such as blood and muscle has been attributed to decreased stem cell activity. The ability of stem cells to cont National Institutes of Health 9/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $97,684 Trans-NIH Recovery Act Research Support Title: T cell Survival and Metabolic Fitness in Inflammation and Infection Purpose:Postdoctoral Fellowship. This funding mechanism is to (1) support the training of scientists at the postdoctoral level, and (2) to advance scientific knowledge of the pr National Institutes of Health 6/17/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $97,684 Trans-NIH Recovery Act Research Support Genetic analysis of the NKT cell response to Streptococcus pneumoniae: Invariant (I) natural killer (NK)T cells are a unique T lymphocyte subset that expresses an invariant T cell antigen receptor (TCR) alpha chain that is conserved between mice and huma National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $97,684 Trans-NIH Recovery Act Research Support Viral infection significantly impacts all forms of life. Since every virus and bacteriophage requires correct organization of its capsid proteins (CPs), the mechanisms by which these CPs assemble must ultimately be determined in order to devise efficaciou National Institutes of Health 6/04/2009
SCRIPPS RESEARCH INSTITUTE, THE $97,684 Trans-NIH Recovery Act Research Support Giardiasis is an important cause of waterborne illness resulting from a one-celled microscopic parasite, Giardia intestinalis (also known as Giardia lamblia). The pathogenic cyst form is protected by an outer shell and can survive outside the body in the National Institutes of Health 6/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $97,441 Trans-NIH Recovery Act Research Support Chemotaxis, or directed cell movement toward a small molecule ligand, plays a key role in many cellular and physiological responses, including metastasis of cancer cells, movement of neutrophils and macrophage in immunity, migration of embryonic cells dur National Institutes of Health 12/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $96,400 Trans-NIH Recovery Act Research Support During the first phase of the AMDCC our group at TJU studied the decorin KO diabetic mouse. Our hypothesis was that decorin acts as an endogenous protective factor by inhibiting active TGF-b. We found that decorin is indeed protective, as decorin KO mice National Institutes of Health 9/07/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $96,379 Trans-NIH Recovery Act Research Support Toll-like receptors (TLRs) are the key sensors of microbes in innate immune cells. TLR activation is central for host defense; nevertheless dysregulation of TLR activation might lead to acute or chronic inflammatory diseases. Thus, the extent and duration National Institutes of Health 7/30/2009
WINDCO PAINTING INC $96,064 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
TEL TECH PLUS, INC. $95,972 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $95,769 Trans-NIH Recovery Act Research Support G protein-coupled receptors (GPCRs) comprise the largest family of cell surface signaling receptors in the mammalian genome, mediate cellular responses to diverse stimuli and control a vast physiological responses. Dysregulated GPCR signaling has been imp National Institutes of Health 6/11/2010
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $94,775 Trans-NIH Recovery Act Research Support A central goal of our current North San Diego Bridges to the Future program is to enhance the academic achievement of underrepresented science majors. Our program does this by providing Supplemental Instruction (SI) for gatekeeper courses in math and the National Institutes of Health 2/19/2010
VALA SCIENCES INC. $94,761 Trans-NIH Recovery Act Research Support These funds were awarded to Vala Sciences Inc (VSI) as a Recovery Act Administrative Supplement to grant 3R41DK082087 Automated quantification of lipid droplets in fatty liver tissue sections. The purpose of the supplement is to fund the purchase of an National Institutes of Health 3/16/2010
VACCINE RESEARCH INSTITUTE OF SAN DIEGO $94,750 Trans-NIH Recovery Act Research Support Non-typhoidal Salmonella, including serotype Typhimurium (STm) are food-borne bacterial pathogens that cause ~1.4 million cases of diarrheal disease annually in the United States and hundreds of millions of cases worldwide. In the intestine, STm induces a
This spending item is part of a $436,000 allocation. See details
National Institutes of Health 8/11/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $94,712 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Gap junctions (GJ) are defined as clusters of closely packed membrane channels containing the connexin protein, connecting two adjoining cells. The channel is composed of two hexamers from each cell and contains oligom National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $93,656 Trans-NIH Recovery Act Research Support One of insulin's major biologic effects is stimulation of glucose transport, and detailed knowledge of the molecular events which mediate this bioeffect will lead to improved understanding of mechanisms of insulin action as well as disease states characte National Institutes of Health 1/15/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $93,577 Trans-NIH Recovery Act Research Support p38-mediated defense pathway against pore-forming toxins. The purpose of the award is to determine which genes are involved in immune protection against pore-forming toxins. Pore-forming toxins (PFTs) are the largest class of protein toxins secreted by National Institutes of Health 7/15/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES $92,265 Trans-NIH Recovery Act Research Support The parent grant focuses on the role of the CRF family peptides, their cognate receptors, and CRF-binding protein on the modulation of endocrine responses to challenge. This work has identified Ucn 2 as a paracrine inhibitor of insulin-induced skeletal m
This spending item is part of a $129,680 allocation. See details
National Institutes of Health 12/04/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $91,041 Trans-NIH Recovery Act Research Support Over the past granting period we have for the first time obtained crystal structures of holoenzyme complexes of PKA. These complexes of the catalytic subunit bound to RI1, RII1 and RII have not only allowed us to understand how the catalytic subunit is in National Institutes of Health 9/30/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $90,900 Trans-NIH Recovery Act Research Support This supplement's aim is to increase our understanding of the mechanism by which airway inflammation may contribute to airway remodeling in asthma. Studies will focus on the role of the airway epithelium and T cells in contributing to airway remodeling u
This spending item is part of a $344,400 allocation. See details
National Institutes of Health 7/26/2010
HLN CONSULTING, LLC $90,000 ARRA - Preventing Healthcare-Associated Infections The ELC program will coordinate and implement HAI prevention activities and report on progress toward reductions in two or more HHS Action Plan Targets. This will include: State HAI Plan coordinator idenitified. Multidisciplinary group convened. ... Show more
This spending item is part of a $737,551 allocation. See details
Centers for Disease Control and Prevention 8/28/2009
SCRIPPS RESEARCH INSTITUTE, THE $89,622 Trans-NIH Recovery Act Research Support The long-term goal of my laboratory is to elucidate the mechanisms that control mechanotransduction in hair cells, and the defects in this process that cause deafness. We propose here to use electrophysiological recordings to determine the extent to which National Institutes of Health 7/17/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $86,776 Trans-NIH Recovery Act Research Support This administrative supplement is a request for personnel to increase the tempo of research on the R01 grant HIV-1 Vpu and BST-2/CD317, by increasing the current level of research/technical support and employment on this project. Specifically, our studies National Institutes of Health 6/01/2010
ELECTRONIC BIOSCIENCES $86,323 Trans-NIH Recovery Act Research Support The goal of this NIH Phase II SBIR Administrative Supplement program is to further develop and demonstrate the capabilities of Electronic Bio Sciences' low noise ion channel measurement system. The system will be further modified from the version develop
This spending item is part of a $198,083 allocation. See details
National Institutes of Health 9/30/2009
ELECTRONIC BIOSCIENCES, INC. $86,323 Trans-NIH Recovery Act Research Support The goal of this NIH Phase II SBIR Administrative Supplement program is to further develop and demonstrate the capabilities of Electronic Bio Sciences' low noise ion channel measurement system. The system will be further modified from the version develop
This spending item is part of a $198,083 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $85,729 Trans-NIH Recovery Act Research Support Nonhuman primates (NHPs) provide powerful animal models for exploring the pathogenesis of infectious and noninfectious diseases, and for testing of new therapies and vaccines that cannot be evaluated in rodents. Over the past decade, the number of NIH gra
This spending item is part of a $376,171 allocation. See details
National Institutes of Health 9/16/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $84,913 Trans-NIH Recovery Act Research Support This project concerns the death of cells through the process called ?apoptosis?, which is critical both for normal physiology and development. Apoptosis is also important for the origin and treatment of various diseases, including cancer, AIDS, and disord National Institutes of Health 6/11/2010
SAN DIEGO UNIFIED SCHOOL DISTRICT $83,333 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $83,179 Trans-NIH Recovery Act Research Support Lesch Nyhan Disease (LND) represents an ideal model human disease in which to study the mechanisms by which even single gene defects produce very complex disruptions of normal genomic, proteomic, biochemical and metabolomic changes function. LND is a thor National Institutes of Health 12/25/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $82,759 The Systolic Blood pressure Intervention Trial, (SPRINT) contractor will conduct a multicenter, randomized clinical trial to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease.
This spending item is part of a $2,491,798 allocation. See details
National Institutes of Health 9/24/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $80,584 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by the applicant) In women, one function most adversely affected by the age-related decrease in ovary reserve is decreased fecundity. The basis for this age-related change is the failure of dominant follicles to release eggs that can National Institutes of Health 9/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $80,584 Trans-NIH Recovery Act Research Support The goal of this renewal grant is to translate our pioneering studies on the biology of bone morphogenetic protein-15 (BMP-15) in rodents to the human. The rationale underpinning the grant is that mutations in the bmp15 gene cause infertility in women due National Institutes of Health 7/29/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $80,436 Trans-NIH Recovery Act Research Support I requested supplemental funding for my grant entitled Foveal and parafoveal codes in reading (HD26765). The goal of the funding request was to enable us to pursue potentially interesting work dealing with reading in deaf readers and older readers. The National Institutes of Health 7/29/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $79,997 Trans-NIH Recovery Act Research Support Group B Streptococcus (GBS), the leading cause of invasive bacterial infections in human newborns, and a common cause of ascending placental infection triggering premature delivery or spontaneous abortion. In studies published in Blood (2009), we showed National Institutes of Health 9/22/2009
LUDWIG INSTITUTE FOR CANCER RESEARCH LTD $79,750 Trans-NIH Recovery Act Research Support Eukaryotic chromosome segregation requires kinetochores, organelles that assemble on condensing chromosomes to form dynamic attachment sites for spindle microtubules. Errors in kinetochore function contribute to chromosomal instability during tumorigenesi National Institutes of Health 1/28/2010
SCRIPPS RESEARCH INSTITUTE, THE $79,595 Trans-NIH Recovery Act Research Support Signaling from G protein-coupled chemoanraetant receptors to the various functional responses of human leukocytes involves Rho small GTPases. P21activated kinases (PAKs) are important downstream mediators of Rho GTPase signaling that regulate crosstalk be National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $78,625 Trans-NIH Recovery Act Research Support Human diseases often arise from excessive or deficient transcription of particular genes in an organism. Proteins known as transcription factors (TF) regulate transcription of a gene through binding specific sites on DNA known as TF binding sites (TFBS). National Institutes of Health 4/23/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $78,152 Trans-NIH Recovery Act Research Support In the post-genome era, it is critical to organize genes and proteins into functional biological networks. Our long-term goal is to dissect the transcriptional regulatory networks that regulate every biological process in the cell, understand the regulato National Institutes of Health 8/11/2009
SCRIPPS RESEARCH INSTITUTE, THE $77,735 Trans-NIH Recovery Act Research Support The overall aim of this research is to investigate the mechanisms by which the CCCH zinc finger protein muscleblind (MBNL), a developmentally programmed regulator of alternative pre-mRNA splicing, recognizes specific regulatory sites in single stranded RN National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $77,250 Trans-NIH Recovery Act Research Support Our research focuses on innate immunity in a model organism, the fruit fly Drosophila. By analyzing immune defenses across species representing diverse habitats, we hope to build a predictive model for innate immune gene expression. Such a model would all National Institutes of Health 9/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $77,250 Trans-NIH Recovery Act Research Support Perceptual disorders are often measured through the inability to rapidly identify visual objects such as faces or words, but these deficits may reflect a change in the certainty associated with potential responses rather than a deficit in the underlying p National Institutes of Health 9/28/2010
SOUND TECHNOLOGIES INC $76,700 Tru-DR Digital Radiograp Detector, Tru-DR a'Cappella, Tru-DR Workstation,Monitor,Generator,Training and shipping National Institutes of Health 3/18/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $76,527 Trans-NIH Recovery Act Research Support There are two major goals for this project: 1) confirm the role of Msr1 during inflammation. 2) Map additional genes that regulate the inflammatory process in a more clinically relevant murine model of sepsis: cecal ligation and puncture. In addition, National Institutes of Health 8/01/2009
SCRIPPS RESEARCH INSTITUTE, THE $75,794 Trans-NIH Recovery Act Research Support This administrative supplement to R01 AI074074 was for acquisition of an item of equipment, a Li-COR Odyssey infrared imaging system. This allows accurate protein quantification of western immunoblots, and 'in-cell' or 'on-cell' westerns. This instrument National Institutes of Health 9/25/2009
EPISCOPAL COMMUNITY SERVICES $75,775 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
SCRIPPS RESEARCH INSTITUTE, THE $75,060 Trans-NIH Recovery Act Research Support Effective treatment of serious mental and cognitive conditions associated with early life and excessive drinking, which afflict growing numbers of humanity. demands greater scientific understanding of the impact that alcohol wields on brain function. The National Institutes of Health 8/03/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $72,860 Trans-NIH Recovery Act Research Support The purpose of this supplement is to create new jobs for our current project that will help to accelerate the analysis of our data and accelerate the publication and translation into policy of results from our research. Our goal in the overall project is National Institutes of Health 9/29/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $69,850 Trans-NIH Recovery Act Research Support This supplement's aim is to increase our understanding of the mechanism by which airway inflammation may contribute to airway remodeling in asthma. Studies will focus on the role of the airway epithelium and T cells in contributing to airway remodeling u
This spending item is part of a $344,400 allocation. See details
National Institutes of Health 7/26/2010
Buccola Engineering Inc $69,825 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $69,588 Trans-NIH Recovery Act Research Support The cerebellum is critical for motor coordination and cognitive function. Granule neurons are a key component of cerebellar circuitry and are thought to represent the cell of origin for the pediatric brain tumor medulloblastoma. Although the development National Institutes of Health 6/21/2011
SCRIPPS HEALTH $68,156 Trans-NIH Recovery Act Research Support Renal transplantation is the treatment of choice for patients with renal failure, but acute and chronic allograft failure remains a critical problem for the transplant recipient. Infections are an independent factor that contributes to renal allograft fa
This spending item is part of a $515,033 allocation. See details
National Institutes of Health 6/04/2010
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $67,216 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The purpose of this application for an ARRA Non-competitive Administrative Supplement is to purchase a single piece of equipment, a SpectraMax M5 multi-mode (absorbance/fluorescence/luminescence) microplate reader. Thi National Institutes of Health 8/31/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $67,151 ARRA ? Equipment to Enhance Training for Health Professionals All the requested equipment has been purchased by the UCSD RMTL: (3) Recording spectrophotometers; (2) High Speed Refrigerated Centrifuge/2-rotors; (1) Refrigerator: 24.4 cu ft isotemp -86 -?C Ultralow temperature; (1) Freeze-Dry Maniford ... Show more
This spending item is part of a $228,291 allocation. See details
Health Resources and Services Administration 9/04/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $66,540 Trans-NIH Recovery Act Research Support Comparative interaction mapping resolves protein complexes and signaling pathways on the basis of their conservation across different species or types of interaction network. It is an emerging methodology which, like comparative genomics, provides a power National Institutes of Health 1/15/2010
SCRIPPS RESEARCH INSTITUTE, THE $66,465 Trans-NIH Recovery Act Research Support The overall purpose of the project is to examine how kinesin motors interact with microtubules. This work will contribute to our understanding how healthy and cancer cells divide. The findings may suggest new approaches for developing novel chemotherapeut National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $66,172 Trans-NIH Recovery Act Research Support Schizophrenia is a common profoundly disabling disorder that carries a heavy burden for patients and families and is the subject of intensive genetic studies. The study of epigenetic variation is an essential complement to conventional genetic disease stu National Institutes of Health 9/30/2009
SAN DIEGO STATE UNIVERSTIY FOUNDATION $65,714 ARRA - Public Health Traineeship Program The mission of the Graduate School of Public Health (GSPH) at San Diego State University (SDSU) is to approach population and individual health by integrating a variety of disciplines to study biomedical, genetic, psychosocial, cultural, environmental, so Health Resources and Services Administration 9/03/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $65,000 Trans-NIH Recovery Act Research Support This supplemental award provides funds to support project 2 and to accelerate the tempo of the parent grant. There are two specific tasks: Task 1: Systematically study and optimize the circulation lifetime of drug delivery motherships and nanoparticle pay
This spending item is part of a $500,000 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $64,804 Trans-NIH Recovery Act Research Support Many NLP applications have been successfully developed to extract information from text. Most of the applications have focused on identifying individual clinical conditions in textual records, which is the first step in making the conditions available to National Institutes of Health 5/02/2011
ZOOLOGICAL SOCIETY OF SAN DIEGO $64,746 Trans-NIH Recovery Act Research Support Most behavioral traits have complex bases and are the result of interactions between multiple genes and/or environments. Therefore, advancing our knowledge of human behavior will require an understanding of the genetic, epigenetic, and environmental bases
This spending item is part of a $309,853 allocation. See details
National Institutes of Health 8/30/2010
Minegar Contracting Inc. $64,490 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SCRIPPS RESEARCH INSTITUTE, THE $63,396 Trans-NIH Recovery Act Research Support The purpose of the proposed study is to identify novel mechanisms regulating the transcriptional activity of Estrogen Related Receptor beta (ERRb). Using a variety of approaches, we expect to identify protein regulators of ERRb and elucidate the specific National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $63,000 Trans-NIH Recovery Act Research Support The Coordinating and Bioinformatics Unit (CBU) for the Animal Models of Diabetic Complications Consortium (AMDCC) and the Mouse Metabolic Phenotyping Centers (MMPC) is responsible for creating and maintaining the administrative, scientific and informatics
This spending item is part of a $1,819,749 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $62,385 Trans-NIH Recovery Act Research Support We recently developed a unique reagent that combines the functions of an anthrax antitoxin and vaccine in a single compound. This reagent is based on multivalent display of the anthrax toxin receptor, ANTXR2, on the surface of an icosahedral insect virus.
This spending item is part of a $522,226 allocation. See details
National Institutes of Health 5/29/2009
SAN DIEGO, COUNTY OF $62,000 Trans-NIH Recovery Act Research Support One potential result of climate change in the United States is increased frequency and intensity of wildland fires. These wildfire fires have the potential to destroy large amounts of public and private property, as was seen during the summer of 2003 and
This spending item is part of a $800,721 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $61,684 Trans-NIH Recovery Act Research Support Neuroimaging studies have identified both macrostructural and microstructural evidence of white matter (WM) tissue maturation continuing through adolescence and into young adulthood. WM development is important for smooth and efficient communication betwe National Institutes of Health 5/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $60,045 Trans-NIH Recovery Act Research Support Gametogenesis in females is controlled by follicle-stimulating hormone (FSH) from the pituitary, which is, in turn, regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH regulates FSH synthesis through induction of the immediate e National Institutes of Health 8/11/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $59,848 Trans-NIH Recovery Act Research Support This R01 revision application answers RFA NOT-OD-09-058 (Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications). This is a revision application for the R01 grant GM076330, titled ?The Ketoreduction and Cy
This spending item is part of a $126,345 allocation. See details
National Institutes of Health 8/27/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $59,785 Trans-NIH Recovery Act Research Support Autophagy is a process that is involved in degradation of long-lived proteins and removal of damaged organelles. Autophagy is generally thought of as a survival process that is upregulated by the cells during periods of starvations, but recent studies ha National Institutes of Health 7/16/2009
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY $59,509 Trans-NIH Recovery Act Research Support The equipment supplement awarded under the American Recovery and Reinvestment Act funded the purchase of an Agilent Bravo robotic device for the Bottini lab and a used SpectraMax Gemini XS Microplate reader, used Beckman J2MI centrifuge and a used GelDoc-
This spending item is part of a $84,744 allocation. See details
National Institutes of Health 1/30/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $58,749 Trans-NIH Recovery Act Research Support The project will procure, process and analyze knees from 100 humans age 20-90 at autopsy each year. The knees are analyzed macroscopically and by various imaging techniques. Tissues, cells, RNA, DNA and protein are isolated from the knees and distributed
This spending item is part of a $4,245,533 allocation. See details
National Institutes of Health 8/14/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $58,393 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Delivery of neurotrophic factors to sites of spinal cord injury (SCI) has been shown to induce axonal growth from different neuronal populations. While cellular growth factor gene delivery is a potent means of promotin National Institutes of Health 8/19/2009
QUAILTY CHILDRENS SERVICES $57,333 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
Dan M Long $56,679 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $55,995 Trans-NIH Recovery Act Research Support Despite the growing number of evidence-based mental health treatments for youth being developed, few are effectively practiced routinely in community settings. One reason may be the lack of attention paid to how these treatments are implemented in the con
This spending item is part of a $454,805 allocation. See details
National Institutes of Health 9/14/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $55,840 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The University of California at San Diego (UCSD) and San Diego State University (SDSU) propose to continue a successful institutional research and academic career development award (IRACDA) program for postdoctoral sch
This spending item is part of a $279,875 allocation. See details
National Institutes of Health 9/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $55,502 Trans-NIH Recovery Act Research Support The goals of this research are to elucidate the complex interactions between the transcriptional coactivators CBPjp300, the tumor suppressor p53, and adenovirus ElA. CBP and p300 regulate most transcriptional process in human cells and are essential for c National Institutes of Health 8/31/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $54,616 Trans-NIH Recovery Act Research Support This project launches a collaborative effort to advance adoption within the HMO Cancer Research Network (CRN) of G?industrial-strengthG? natural language processing (NLP) systems useful for mining valuable, research-grade information from unstructured cli
This spending item is part of a $992,334 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $54,161 Trans-NIH Recovery Act Research Support Obesity has become a widespread health problem reaching an epidemic level in our society, with the affected individuals having a high risk for diabetes, heart disease, hypertension and cancer. The adipocyte- derived hormone leptin regulates energy balance National Institutes of Health 3/19/2010
LUDWIG INSTITUTE FOR CANCER $53,471 Trans-NIH Recovery Act Research Support DNA mismatch repair (MMR) plays a number of critical roles in eukaryotic cells including: 1) suppression of mutations that result from misincorportation errors during DNA replication as well as chemical damage to DNA and DNA precursors; 2) repair of mispa National Institutes of Health 7/17/2009
SCRIPPS RESEARCH INSTITUTE, THE $52,625 Trans-NIH Recovery Act Research Support We received funds to enable hiring of a University of California (UCSD) and a Harvard undergraduate student (both US citizens) for full time summer research experience. One student has been working part time in my lab, unpaid, for course credit during th National Institutes of Health 5/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $52,023 Trans-NIH Recovery Act Research Support Twin studies have provided insights into multiple disease and developmental endpoints. Because their genetic and environmental similarities are easily understood, twins can elucidate the contributions of genetic and environmental factors to illness and he
This spending item is part of a $7,654,551 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $51,910 Trans-NIH Recovery Act Research Support Urinary Incontinence Treatment Network (UITN): ValUE: Value of Urodynamic Evaluation The primary aim of this randomized clinical trial is to determine if women desiring surgery for diagnosed, uncomplicated predominant stress urinary incontinence (UI) who National Institutes of Health 1/25/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $51,807 Trans-NIH Recovery Act Research Support Twin studies have provided insights into multiple disease and developmental endpoints. Because their genetic and environmental similarities are easily understood, twins can elucidate the contributions of genetic and environmental factors to illness and he
This spending item is part of a $7,654,551 allocation. See details
National Institutes of Health 9/29/2009
SCRIPPS RESEARCH INSTITUTE, THE $51,710 Trans-NIH Recovery Act Research Support Under normal conditions, most T lymphocytes are made in the thymus. However, the thymus degenerates with age, beginning around puberty. Because output of new Tcells from the thymus is proportional to its mass, age-related thymic atrophy results in a prog National Institutes of Health 6/04/2009
SCRIPPS RESEARCH INSTITUTE, THE $51,710 Trans-NIH Recovery Act Research Support Coxsackievirus B (CVB) infection is the most common infectious cause of heart inflammation and can lead to chronic disease and cardiac failure. I have found that CVB3 induces minimal T cell responses in a murine model of infection and this may be associat National Institutes of Health 7/22/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $51,635 Trans-NIH Recovery Act Research Support The main focus of this project is to further understand the laminar circuitry of the cerebral cortex that underlies the enhanced visual sensory processing due to attentional selection. The neural circuitry that is embedded within layered structure of the National Institutes of Health 7/21/2009
SCRIPPS HEALTH $51,016 Trans-NIH Recovery Act Research Support The 4DB Center's potential impact is on two fronts, the basic research ability to conduct physical sciences experiments on cancer patient samples in a meaningful way and to generate the force and time journey of cancer cells during the metastatic phase. T
This spending item is part of a $3,878,972 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $50,770 Trans-NIH Recovery Act Research Support Despite the large number of pregnant women and neonates infected with HIV receiving long-term treatment with antiretroviral agents, little is understood about the handling of these drugs in utero and in the neonatal kidney. Although the drugs are generall National Institutes of Health 12/07/2009
SCRIPPS RESEARCH INSTITUTE, THE $50,325 Trans-NIH Recovery Act Research Support The overreaching goal of this project is to determine the structure and mechanism of the human RISC-loading complex (RLC). The RLC catalyzes the initiation of the microRNA pathway, which is linked to many forms of human disease, and is the intracellular t National Institutes of Health 9/30/2009
HLN CONSULTING, LLC $50,000 ARRA - Health Information Technology - Beacon Communities The San Diego Beacon Community Collaborative proposes to advance the existing health information technology (IT) infrastructure in our region. Our goal is to foster data exchange, interoperability, and clinical integration for meaningful use a... Show more
This spending item is part of a $15,275,115 allocation. See details
Health and Human Services, Department of 5/04/2010
UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION $48,237 Trans-NIH Recovery Act Research Support A central goal of our current North San Diego Bridges to the Future program is to enhance the academic achievement of underrepresented science majors. Our grant accomplishes this by providing Supplemental Instruction (SI) for courses in mathematics and National Institutes of Health 7/13/2009
SCRIPPS RESEARCH INSTITUTE, THE $48,121 Trans-NIH Recovery Act Research Support The 2 summer students that were employed under ARRA subcontract, Pial Hossain and Doug Jacobs, were both pre-med students at UCSD and Brown University, respectively. Each of them was assigned to a particular subtopic of our ongoing grant that aims at unde National Institutes of Health 6/04/2009
EDUCATIONAL ENRICHMENT SYSTEMS, INC. $47,333 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $46,868 Trans-NIH Recovery Act Research Support The advent of ultrashort laser light pulses as a laboratory tool provides an opportunity to probe and manipulate anatomy and function in nervous systems. Ultrashort pulses are the essential means to drive the nonlinear absorption of light by biomolecules,
This spending item is part of a $94,948 allocation. See details
National Institutes of Health 8/28/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $45,999 Trans-NIH Recovery Act Research Support This supplemental award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ANBL0931, which is a Phase III Study of Chimeric Antibody 14.18 in High-Risk Neuroblastoma. The primary objective of study ANBL09
This spending item is part of a $1,981,588 allocation. See details
National Institutes of Health 8/07/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $45,839 Trans-NIH Recovery Act Research Support The goal of this project is to decipher molecular signaling mechanisms for control of insulin biosynthesis and secretion, and the immediate focus is on dissecting the function of Shp2 tyrosine phosphatase in orchestrating signaling cascades in ( cells. Al National Institutes of Health 6/17/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $45,162 Trans-NIH Recovery Act Research Support A summer supplement for university students is requested under the American Recovery and Reinvestment Act. This will provide scientific instruction and temporary employment for four talented individuals. They will be trained in protein biochemistry, cryst National Institutes of Health 5/19/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $45,162 Trans-NIH Recovery Act Research Support A summer supplement for university students is requested under the American Recovery and Reinvestment Act. This will provide scientific instruction and temporary employment for four talented individuals. They will be trained in protein biochemistry, cryst National Institutes of Health 5/19/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $45,095 Trans-NIH Recovery Act Research Support This fund is an ARRA administrative supplement to Fund #50437N entitled, 'Behavioral and MRI Evaluation of Prenatal Alcohol Exposure.' The supplement will provide support for an undergraduate college student who will support the research efforts of the pa National Institutes of Health 6/17/2009
SCRIPPS RESEARCH INSTITUTE, THE $44,748 Trans-NIH Recovery Act Research Support Both naive CD4+ and COB+ T cells are dependent on two types of signaling, from contact with IL-7 and self-MHC/peptide ligands, for their continued survival under normal conditions and to undergo homeostatic proliferation in response to lymphopenia. Naive National Institutes of Health 7/15/2009
SCRIPPS RESEARCH INSTITUTE, THE $44,170 Trans-NIH Recovery Act Research Support The present supplement application seeks support for summer research experiences at The Scripps Research Institute for two talented high school interns in the San Diego area. The work to be performed by the interns is directly relevant to the studies and National Institutes of Health 8/03/2009
INDIAN HEALTH COUNCIL $44,000 ARRA - IHS Tribal Agreements Funding will be used for medical equipment to improve the provision of health care at IHC. The protable imaging system, vacuum and air delivery, and tablet/capsule counting machine will be used by Indian Health Council. Indian Health Service 3/12/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $43,536 Trans-NIH Recovery Act Research Support The Fetal Alcohol Effects and Choline Intervention project examines the potential of choline, an essential nutrient, to reduce the severity of neuropathology and behavioral alterations associated with developmental alcohol exposure. Using an animal model National Institutes of Health 9/03/2010
Alcal/Arcade Contracting, Inc. $42,344 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $41,973 Trans-NIH Recovery Act Research Support Abstract In the fields of biomaterials and tissue engineering, the ability to modulate cell behavior on surfaces is essential, particularly when attempting to direct cell growth and differentiation, both for in vitro engineered tissue and generating cell National Institutes of Health 8/07/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $40,803 Trans-NIH Recovery Act Research Support This fund is an ARRA administrative supplement to 53311E entitled, 'A Multisite Neurobehavioral Assessment of Fetal Alcohol Spectrum Disorders.' The supplement will be used to hire undergraduate college students who will support the research efforts of th National Institutes of Health 7/10/2009
SCRIPPS RESEARCH INSTITUTE, THE $40,109 Trans-NIH Recovery Act Research Support Our Center for the Structural Biology of Cellular Host Elements in Egress, Trafficking, and Assembly of HIV CHEETAH studies the structural biology of HIV/Host interactions involved in viral trafficking and assembly. Here, we request funds that will enabl
This spending item is part of a $467,025 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $39,862 Trans-NIH Recovery Act Research Support The overall aim of this Mentored Research Scientist Career Development (K01) Award is for the candidate to gain new skills so that she may become an independent researcher in the area of neuroimaging, particularly with respect to understanding the neurobe National Institutes of Health 9/24/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $38,625 Trans-NIH Recovery Act Research Support Localization of mRNAs with subsequent translation into new proteins provides a means to geographically regulate neuronal protein composition in distinct subcellular regions. In axons, this localized protein synthesis is needed for growth cone guidance and
This spending item is part of a $332,375 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $38,625 Trans-NIH Recovery Act Research Support The real-time chemistry of life occurs at the interfaces of proteins and small chemicals present in the cellular environment. For the first time in history, sufficient information on the human proteome and its interacting chemogenome has accumulated in th
This spending item is part of a $2,093,862 allocation. See details
National Institutes of Health 7/16/2010
ACCELRYS, INC. $38,500 Procure through purchase/license new commercial off the shelf (COTS) software to integrate with the Cambridge Soft software utilized for the collection of all data generated on Chemical Biology Consortium projects that are conducted within the NCI, at SAI
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 11/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $37,614 Trans-NIH Recovery Act Research Support The recognition of the hierarchies of genetic pathways coordinating heart development remains incomplete, in part because of the difficulties to identify the critical cis-acting sequences that are required for the regionalized expression of genes during c
This spending item is part of a $843,762 allocation. See details
National Institutes of Health 6/01/2009
SCRIPPS RESEARCH INSTITUTE, THE $37,415 Trans-NIH Recovery Act Research Support The parent grant focuses on the role of the CRF family peptides, their cognate receptors, and CRF-binding protein on the modulation of endocrine responses to challenge. This work has identified Ucn 2 as a paracrine inhibitor of insulin-induced skeletal m
This spending item is part of a $129,680 allocation. See details
National Institutes of Health 12/04/2009
VALA SCIENCES INC. $37,200 Trans-NIH Recovery Act Research Support The purpose of the ARRA Administrative Supplement Providing Summer Research Experiences, which was awarded to Vala Sciences Inc, was to support the research being conducted at Vala for the NIH SBIR project 3R44DK074333 HT Image Assay of Lipid Droplet Form National Institutes of Health 7/13/2009
Scott Fences $36,800 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $36,734 Trans-NIH Recovery Act Research Support In the skeletally mature individual, hyaline articular cartilage does not heal effectively when injured and the natural progression of acquired articular cartilage defects is predictably poor, commonly culminating in joint arthrosis. Physician and patient National Institutes of Health 5/27/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $36,734 Trans-NIH Recovery Act Research Support Articular cartilage is one of a number of tissues in the body that bears load and slides relative to an apposing tissue surface with remarkable tribological propertieslow friction, low wear, and multiple modes of lubrication acting to lower friction and/o National Institutes of Health 5/26/2010
RINCON BAND OF LUISENO MISSION INDIANS OF THE RINCON RESERVATION CALIFORNIA $34,851 ARRA - Head Start Quality improvement of Head Start program and cost of living adjustment for Head Start staff in accordance with the FY 2009 Funding Guidance ACF-PI-HS-09-06 dated April 2, 2009 Administration for Children and Families 7/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $34,708 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Reading the literature on any neurodegenerative condition quickly leads to a bewildering array of facts, some contradictory, regarding the correlations between known pathological and clinical features of the disease. T National Institutes of Health 7/26/2009
SIALIX, INC. $34,344 Trans-NIH Recovery Act Research Support Gc-Free, Inc. is currently funded under STTR, 1R41GM080959-01A1, has obtained a 2-year no cost extension, and has received a supplement grant funded under the NIH American Recovery and Reinvestment Act appropriation. The research funded under this supple National Institutes of Health 9/25/2009
SCRIPPS RESEARCH INSTITUTE, THE $33,932 Trans-NIH Recovery Act Research Support The present supplement application seeks support for a 2 summers of paid research experience at The Scripps Research Institute for an undergraduate with very high potential for a biomedical research career, a current junior at the University of San Diego. National Institutes of Health 8/03/2009
PROGRESSIVE INVESTMENTS, INC. $33,800 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $33,638 Trans-NIH Recovery Act Research Support The Fetal Alcohol Effects and Choline Intervention project examines the potential of choline, an essential nutrient, to reduce the severity of neuropathology and behavioral alterations associated with developmental alcohol exposure. Using an animal model National Institutes of Health 6/17/2009
SAN DIEGO STATE UNIVERSITY FOUNDATION $33,010 Trans-NIH Recovery Act Research Support Chemosensory Perception and Psychophysics in the Aged- Administrative Supplement to parent grant 55736A 'Chemosensory Perception and Psychophysics in the Aged. Funding is provided under ARRA supplement to support undergraduate research assistants to prom National Institutes of Health 6/22/2009
CAREFUSION SOLUTIONS, LLC $31,987 Purchase of Alaris Equipment National Institutes of Health 7/19/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $31,851 Trans-NIH Recovery Act Research Support Temporomandibular joint disorders (TMJD), including osteoarthritis and internal derangement, have a high prevalence in the adult population and often cause pain and limited jaw function. Severe deterioration of the articular cartilage of the mandibular co National Institutes of Health 5/01/2009
CAMPO BAND OF MISSIONS INDIANS $31,765 ARRA Child Care and Development Block Grant Title: ARRA SSupplemental Funding for the Child Care and Development Fund (CCDF; Description: The CCDF ARRA funds will be used to provide child care financial assistance to low-income working families and funcd activities to improvber the quality of child Administration for Children and Families 4/09/2009
TARGESON LLC $31,500 Trans-NIH Recovery Act Research Support This supplement award was used to support salary for a full-time laboratory technician to work on a previously-awarded SBIR grant. This award enabled Targeson to hire one technican, who had been working part-time for the Company on an hourly basis, at ful National Institutes of Health 5/21/2010
SCRIPPS RESEARCH INSTITUTE, THE $31,500 Trans-NIH Recovery Act Research Support Cell motility is a basic process that contributes to both normal (e.g. wound healing) and pathological (e.g. metastasis) cell behavior. Underlying the migratory abilities of cells are the dynamics of actin at the leading edge, regulated in response to Rho National Institutes of Health 8/13/2010
SCRIPPS RESEARCH INSTITUTE, THE $31,187 Trans-NIH Recovery Act Research Support Purpose and Expected Outcomes: The goal of this research is to adapt the methods used in the national trial Diabetes Prevention Program, DPP, to the specific needs of high-risk, low-income Latino women with a history of gestational diabetes. We will use
This spending item is part of a $597,109 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $30,900 Trans-NIH Recovery Act Research Support Our overall goals are to: (1) coordinate investigations of South Pacific organisms as pharmaceutical resources for treating diseases of importance in the Pacific Islands and United States and for novel bioenergy applications (2) support sustainable uses o National Institutes of Health 9/09/2009
SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE $30,624 Trans-NIH Recovery Act Research Support Williams syndrome (WS) is a neurodevelopmental condition that is caused by a hemizygous deletion of roughly 1.5-1.8 megabases, a region of chromosome band 7q11.23 that contains about 28 genes. Found in 1 in 7500-20,000 live births, persons with WS have ch
This spending item is part of a $245,038 allocation. See details
National Institutes of Health 9/07/2010
UNIVERSITY OF CALIFORNIA, SAN DIEGO $30,000 Trans-NIH Recovery Act Research Support We are requesting a supplement to the parent grant to purchase of equipment necessary to allow us to quantify mRNA in our oligodendrocyte cell cultures. We will initially measure mRNA of proteins known to be induced in oligodendrocytes by diabetes that National Institutes of Health 12/21/2009
CHILDREN OF THE RAINBOW HEAD START LLC $28,633 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $28,428 Trans-NIH Recovery Act Research Support The long-term objective of this proposal is to advance research in the area of physical activity promotion for persons with multiple sclerosis (MS) by implementing and evaluating a multifaceted intervention that can be translated into public health and re
This spending item is part of a $93,468 allocation. See details
National Institutes of Health 9/13/2010
EPISCOPAL COMMUNITY SERVICES $27,555 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $26,557 Trans-NIH Recovery Act Research Support Summary of the parent grant: The parent grant (R01 EB006200-04) proposed the development of a Continuous-Imaging HT Screening Instrument that would allow a 10-fold speed increase over the current Beckman Coulter IC-100 instrument. This increase would be g National Institutes of Health 6/16/2009
SCRIPPS RESEARCH INSTITUTE, THE $26,000 Trans-NIH Recovery Act Research Support The present administrative supplement is for the purchase of an alcohol vapor inhalation system to expose mice 10 intermittent alcohol vapors to induce alcohol dependence as proposed in the original application. This request is motivated by the limited ca National Institutes of Health 9/16/2009
A.E.L. CONSTRUCTION, INC. $25,593 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $25,000 Trans-NIH Recovery Act Research Support The scope of the parent grant (1R03HD059717-01) is the Screening of Human Milk Oligosaccharides that Protect Infants from HIV Infections. Breast-feeding is the predominant transmission route for HIV-1 infection in children. However, the vast majority of b National Institutes of Health 9/01/2010
ACCELRYS, INC. $25,000 Procure through purchase/license new commercial off the shelf (COTS) software to integrate with the Cambridge Soft software utilized for the collection of all data generated on Chemical Biology Consortium projects that are conducted within the NCI, at SAI
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 11/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $23,787 Trans-NIH Recovery Act Research Support This award supported three college students to work in the laboratory over 11 weeks in the summer of 2009 and gain hands on experience at the bench so that they might consider a career in science. During their time in the laboratory, the students were g National Institutes of Health 6/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $23,642 Trans-NIH Recovery Act Research Support In patients with chronic thromboembolic pulmonary hypertension (CTEPH), elevated pulmonary vascular resistance (PVR) is caused by obstruction of proximal and distal pulmonary arteries with thromboemboli, and by pulmonary vascular remodeling due to excessi National Institutes of Health 6/05/2009
NORTH COUNTY COMMUNITY SERVICES $22,588 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $22,450 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $21,778 Trans-NIH Recovery Act Research Support Asthma incidence is increasing and warrants investigation of distinct immune mechanisms. Innate, non- antigen-dependent immunity has been shown to play a role in allergic responses. Our data suggest that the innate immune collectin, surfactant (SP-)-D, ca National Institutes of Health 7/14/2009
CAJON VALLEY UNION SCHOOL DIST. $21,667 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
DARYL GRIFFIS ACOUSTICS, INC. $21,400 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $20,629 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Relevance: Alcohol and other drug use are common among U.S. adolescents. Our prior studies found that adolescents with alcohol use disorders (AUD) show abnormalities on indices .of brain functioning, including neuropsy National Institutes of Health 7/14/2009
SAN DIEGO COUNTY OFFICE OF EDUCATION $20,454 ARRA - Prevention and Wellness--Communities Putting Prevention to Work The four evaluation projects that will be implemented under this project for enhanced evaluation are: 1.) Implementation of a sustainable community-wide BMI surveillance system through linkage of health care providersG?? EHRs to ... Show more
This spending item is part of a $1,768,581 allocation. See details
Centers for Disease Control and Prevention 9/28/2010
ILLUMINA, INC. $18,788 Purchase Order# HHSN311200900249P was issued from National Institute of Health/NIA to Illumina Inc. in the amount of $18,788.00 for sequencing reagents. National Institutes of Health 6/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $18,367 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Proteolytic processing of proenkephalin (PE) is required to produce active enkephalin opioid peptides that regulate analgesia, behavior, and immune cell function. It is, therefore, critical to define the multi-step pro National Institutes of Health 6/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $17,604 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for one college student in health related scientific research. National Institutes of Health 7/27/2009
CHICANO FEDERATION OF SAN DIEGO COUNTY $16,667 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
OCEANSIDE UNIFIED SCHOOL DISTRICT $16,500 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
VOLUNTEERS OF AMERICA, INC. $16,385 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $15,690 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
CHILDREN OF THE RAINBOW HEAD START LLC $15,053 ARRA - Head Start Name of Project: Head Start Head Start promotes the school readiness of low-income children through the provision of comprehensive health, developmental and family services. The program serves 7,759 children between the ages of 3-5 years. Name of Projec
This spending item is part of a $4,366,839 allocation. See details
Administration for Children and Families 6/30/2009
Best Maintenance Inc $14,712 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
CUSTOM INTERIORS BY YIGAEL, INC. $14,700 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $14,015 Trans-NIH Recovery Act Research Support Administrative Supplement - The purpose of the supplement is to pursue the knockdown of Siglec-5 in chimpanzee T cells using small interfering RNA. The student will work an experienced postdoc in the lab to optimize this knockdown first in model cells, National Institutes of Health 6/08/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $13,625 Trans-NIH Recovery Act Research Support The overall goal of the parent grant is to develop accurate methods for computing noncovalent binding affinities and thereby speed the discovery of new medications and targeted molecules for other biomedical applications.-? This Administrative Supplement
This spending item is part of a $39,620 allocation. See details
National Institutes of Health 6/18/2010
Fallbrook Child Development Center Inc $13,244 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
SUPERIOR DOOR SYSTEMS INC $13,210 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $12,165 Trans-NIH Recovery Act Research Support The overall goals of the project are: 1) to further elucidate how S-nitrosylation and subsequent oxidation can mimic genetic mutations involved in familial PD to cause protein misfolding, abnormal signaling, and eventually neuronal cell injury and death; National Institutes of Health 5/28/2010
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $12,000 Trans-NIH Recovery Act Research Support Participants at last year's CNS meeting in RTP discussed the meeting venue for 2010 and investigators reached consensus that a West Coast location would be preferable, as two of the CNS programs are located on the West Coast. The Catamaran Resort Hotel a National Institutes of Health 7/17/2010
SEACOAST SCIENCE, INC. $11,376 Trans-NIH Recovery Act Research Support Summer Intern support for NIEHS program developing w-cost chemical sensors for detecting and monitoring environmental clean-up, remediation, and decommissioning processes where groundwater may be contaminated. National Institutes of Health 7/10/2009
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $11,000 Trans-NIH Recovery Act Research Support Cholesterol is a critical nutrient that is required as a structural component of cell membranes and is a precursor in the biosynthesis of steroid hormones and bile acids. It is important that cholesterol levels are properly regulated because aberrant meta National Institutes of Health 9/29/2010
Benchmark Landscape, Inc. $10,936 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SAN DIEGO STATE UNIVERSITY $10,872 Trans-NIH Recovery Act Research Support This fund is an ARRA administrative supplement to 54066D entitled, 'Language, Modality and the Brain.' The supplement provides summer research experience for students and science educators and will investigate: a) the neural substrates underlying percepti National Institutes of Health 6/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $10,185 Trans-NIH Recovery Act Research Support Title: Regulation of Synapse Specificity in the Developing CNS. This award supports undergraduate research in the laboratory by providing them with paid employment during the summer and fall. Three undergraduate students will work on this project to gener National Institutes of Health 7/21/2009
PALA BAND OF MISSION INDIANS $8,930 Aging Nutrition Services for Native Americans 2009 T6_ARRA Administration on Aging 3/30/2009
SOUTHERN INDIAN HEALTH COUNCIL, INC $8,930 Aging Nutrition Services for Native Americans 2009 T6_ARRA Administration on Aging 3/30/2009
SOUTHERN INDIAN HEALTH COUNCIL, INC $8,930 Aging Nutrition Services for Native Americans 2009 T6_ARRA Administration on Aging 3/30/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $7,000 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) in children is a devastating illness. The prevalence of patients aged 0 ? 19 years with ESRD has grown 32% since 1990 and the mortality rate for children with ESRD receiving dialysis therapy is between 30 and 150 times that o
This spending item is part of a $525,000 allocation. See details
National Institutes of Health 9/27/2009
VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO $6,868 Trans-NIH Recovery Act Research Support This is a Diversity supplement to support an undergraduate student Yen Phan for a summer research project July 1 to August 31, 2009. A summer research project will introduce Yen Phan to biomedical research which will help her in her future career. National Institutes of Health 7/13/2009
GROSSMONT-CUYAMACA COMMUNITY COLLEGE DISTRICT $6,667 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
JAMUL-DULZURA UNION SCHOOL DISTRICT $6,667 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
METROPOLITAN AREA ADVISORY COMMITTEE ON ANTI-POVERTY OF SAN DIEGO COUNTY INC $6,581 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
BOYS & GIRLS CLUBS OF GREATER SAN DIEGO $6,500 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
Yingst TV & Appliance $6,325 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
NORTH COUNTY SERENITY HOUSE, INC. $6,213 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
ESCONDIDO COMMUNITY CHILD DEVELOPMENT CENTER $5,533 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $5,124 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
Casper's Concrete Cutting, Inc. $4,871 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
SCRIPPS RESEARCH INSTITUTE, THE $4,570 Trans-NIH Recovery Act Research Support The main objective of this project is to achieve a better understanding of how alcohol addiction and withdrawal affects neuronal communication in the central nervous system at levels of single neurons and neural circuits. Specifically, the collaborating s
This spending item is part of a $980,018 allocation. See details
National Institutes of Health 9/18/2009
San Diego Glass Coatings $3,279 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009
VISTA UNIFIED SCHOOL DISTRICT $2,837 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
SAN MARCOS UNIFIED SCHOOL DISTRICT $1,200 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
GROSSMONT-CUYAMACA COMMUNITY COLLEGE DISTRICT $764 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
GROSSMONT UNION HIGH SCHOOL DISTRICT SCHOOL FACILITIES CORPORATION $655 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
SAN DIEGO COMMUNITY COLLEGE DISTRICT $596 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
ESCONDIDO UNION HIGH SCHOOL DISTRICT $480 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
SAN DIEGO UNIFIED SCHOOL DISTRICT $462 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
OCEANSIDE UNIFIED SCHOOL DISTRICT $437 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
CARLSBAD UNIFIED SCHOOL DISTRICT $218 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
PALOMAR COMMUNITY COLLEGE DISTRICT FINANCING CORPORATION $131 ARRA Child Care and Development Block Grant Title: ARRA Supplemental Funding for Child Care and Development Fund (CCDF); Description: Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $220,273,864 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $0 Trans-NIH Recovery Act Research Support The Hepatitis C Virus (HCV) E2 glycoprotein is a novel kinase that initiates signal transduction mechanisms modulating the following pathways: 1.) Clathrin-mediated endocytosis, through a site-specific phosphorylation of the clathrin adaptor protein-50 (A
This spending item is part of a $45,413 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $0 Trans-NIH Recovery Act Research Support The nuclear factor kappa B (NF-kB) family of transcription factors controls inter- and intracellular signaling, cellular stress responses, cell growth, survival, and apoptosis. In resting cells, NF-kB dimers with transcription activation potential are seq
This spending item is part of a $127,463 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CALIFORNIA, SAN DIEGO $0 Trans-NIH Recovery Act Research Support This application for renewal of the California NeuroAIDS Tissue Network (CNTN) responds to RFA-MH-08-021. The CNTN is part of the National NeuroAIDS Tissue Consortium (NNTC) which includes sites at the Mt. Sinai School of Medicine, UCLA, and University of National Institutes of Health 8/28/2009
VISTA COMMUNITY CLINIC $0 ARRA Health Center Integrated Services Development Initiative[g1] The Vista Community Clinic FIP project is the expansion of its system's flagship service site, Vale Terrace, to accommodate 12,200 new, low-income, unduplicated users across 42,760 visits annually, and expanding enabling services. The... Show more
This spending item is part of a $11,473,212 allocation. See details
Health Resources and Services Administration 10/19/2009