Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Baltimore (City) County, Md., funds by Health and Human Services, Department of

Listing $2,514,102,550.89 in stimulus funds from Health and Human Services, Department of for Baltimore (City)

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $240,215,546 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2011 QUARTER 1 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 12/30/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $215,392,884 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2010 QUARTER 2 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 5/20/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $209,787,521 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2010 QUARTER 1 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 3/11/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $200,117,281 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2009 QUARTER 4 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 11/30/2009
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $186,194,028 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2010 QUARTER 4 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 9/10/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $179,267,087 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2011 QUARTER 2 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 4/26/2011
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $177,717,945 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2010 QUARTER 3 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 9/10/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $166,036,000 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2009 QUARTER 3 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 4/03/2009
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $147,577,488 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2011 QUARTER 3 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 7/19/2011
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $138,518,372 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2009 QUARTER 2 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 2/24/2009
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $136,990,226 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2009 QUARTER 1 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 2/24/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $37,355,585 ARRA -+ Emergency Contingency Fund for Temporary Assistance for Needy Families (TANF) State Program 2010 TANFS Administration for Children and Families 8/24/2010
MD ST DEPARTMENT OF HUMAN RESOURCES $35,921,239 Child Support Enforcement 2011 OCSE Administration for Children and Families 1/24/2011
MD ST DEPARTMENT OF HUMAN RESOURCES $30,449,541 ARRA -+ Emergency Contingency Fund for Temporary Assistance for Needy Families (TANF) State Program 2009 TANFS Administration for Children and Families 8/24/2010
EDUCATION, MARYLAND DEPARTMENT OF $23,294,651 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $24,040,405 allocation. See details
Administration for Children and Families 4/09/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $18,228,963 Child Support Enforcement 2010 OCSE Administration for Children and Families 11/23/2009
JOHNS HOPKINS UNIVERSITY, THE $14,984,116 National Center for Research Resources, Recovery Act Construction Support This proposal is for an infrastructure upgrade and modernization of the laboratory facilities housed in the North Wing of the principal building of the Johns Hopkins Bloomberg School of Public Health (JHSPH). The JHSPH, founded... Show more National Institutes of Health 3/04/2010
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $12,726,000 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2012 QUARTER 2 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 1/01/2012
UNIVERSITY OF MARYLAND $7,994,900 Trans-NIH Recovery Act Research Support NIH-funded principal investigators at the University of Maryland, Baltimore (UMB), the University of Maryland, Baltimore County (UMBC), and the University of Maryland, College Park (UMCP) have scientific need for a state-of-the-art shielded 950 MHz NMR be National Institutes of Health 5/27/2010
UNIVERSITY OF MARYLAND $7,329,060 Trans-NIH Recovery Act Research Support The University of Maryland School of Medicine (UMSOM) proposes to renovate 27,000 gross square feet of lab, office, and conference space on the sixth and seventh floors of the Frank C. Bressler Research Building (BRB). The proposed renovation project will National Institutes of Health 3/18/2010
Dome Corporation $7,000,028 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We request funds to develop a Translational Molecular Imaging Center (TMIC) on the Johns Hopkins Bayview (JHB) medical campus. There is currently no such center at the Johns Hopkins Medical Institutions (JHMI) and few, National Institutes of Health 3/31/2010
MD ST DEPARTMENT OF HUMAN RESOURCES $6,365,727 Foster Care_Title IV-E FY 2009 FOSTER CARE Administration for Children and Families 7/06/2009
JOHNS HOPKINS UNIVERSITY, THE $6,052,279 Trans-NIH Recovery Act Research Support Schizophrenia is a common profoundly disabling disorder that carries a heavy burden for patients and families and is the subject of intensive genetic studies. The study of epigenetic variation is an essential complement to conventional genetic disease stu
This spending item is part of a $6,354,022 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $5,280,448 The goal of this funding initiative on ?Comprehensive Comparative Effectiveness Reviews for Effective Health Care? is to improve understanding of the comparative effectiveness and safety of medications, procedures, tests, and management strategies for pat Agency for Healthcare Research and Quality 10/27/2009
UNIVERSITY OF MARYLAND $5,000,000 National Center for Research Resources, Recovery Act Construction Support With the assistance of the National Center of Research Resources, National Institutes of Health, Department of Health and Human Services and funds awarded under the American Recovery Act Limited Competition: Extramural Research... Show more National Institutes of Health 1/29/2010
BALTIMORE, CITY OF $4,606,217 ARRA - Community Services Block Grant Community Services Block Grant ARRA funding provides economic stimulus while furthering the mission under CSBG to promote the economic and social well-being of children, youth, families and communities. The funding is used for activities that contribute t
This spending item is part of a $13,719,817 allocation. See details
Administration for Children and Families 4/10/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $4,350,268 Foster Care_Title IV-E FY 2010 FOSTER CARE Administration for Children and Families 1/03/2010
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $4,234,000 Trans-NIH Recovery Act Research Support We propose to purchase an 11.7T animal research Magnetic resonance imaging (MRI) and spectroscopy (MRS) scanner for the F.M. Kirby Research Center at Kennedy Krieger Institute (KKI). This scanner will be equipped with the latest coil technology (mouse cry National Institutes of Health 4/08/2010
MD ST DEPARTMENT OF HUMAN RESOURCES $4,156,450 Child Support Enforcement 2009 OCSE Administration for Children and Families 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $3,844,473 The Partnership in Applied Comparative Effectiveness Science (PACES) is an initiative that seeks to advance the science for comparative effectiveness research by leveraging available clinical trial data held by the Food and Drug Administration (FDA). The
This spending item is part of a $4,662,128 allocation. See details
Food and Drug Administration 9/19/2010
JOHNS HOPKINS UNIVERSITY, THE $3,752,512 ARRA - Health Information Technology Professionals in Health Care This funding opportunity is for Information Technology Professionals in Health Care: Program of Assistance for University-Based Training grants to be funded under section 3016 of the Public Health Service Act, as added by the American ... Show more Health and Human Services, Department of 4/02/2010
JOHNS HOPKINS UNIVERSITY, THE $3,342,484 End Stage Renal Disease (ESRD) is a growing public health burden. Cardiovascular disease (CVD) is a major source of morbidity and mortality in patients with ESRD, but optimal strategies for reducing CVD related morbidity and mortality are not fully explor
This spending item is part of a $4,556,778 allocation. See details
Agency for Healthcare Research and Quality 7/14/2010
JOHNS HOPKINS UNIVERSITY, THE $3,239,259 Trans-NIH Recovery Act Research Support North American AIDS Cohorts Collaboration on Research and Design A disturbing increase in the incidence of non-AIDS-defining conditions including renal disease, metabolic and cardiovascular disease, and malignancies has been observed in recent years, and
This spending item is part of a $7,312,062 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $3,147,857 Trans-NIH Recovery Act Research Support Recruitment of New Faculty in NCI Designated Cancer Centers (P30). Two awards were given:1 in the Division of Immunology(Dung Le) and the other in Radiation Oncology(Russel Hales) National Institutes of Health 9/18/2009
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $2,751,347 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2011 QUARTER 4 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 9/01/2011
MD ST DEPARTMENT OF HUMAN RESOURCES $2,681,732 Adoption Assistance FY 2009 ADOPTION ASSISTANCE Administration for Children and Families 7/01/2009
JOHNS HOPKINS UNIVERSITY, THE $2,483,116 Trans-NIH Recovery Act Research Support For this ARRA RFA-OD-09-004 GO application, we propose to perform an integrated genome-wide mutational analysis of oral cancers using high throughput sequence analysis of coding genes combined with analyses of copy number, gene expression, and methylation National Institutes of Health 9/24/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $2,468,351 Adoption Assistance FY 2010 ADOPTION ASSISTANCE Administration for Children and Families 1/15/2010
ENVIRONMENTAL & DEMOLITION SERVICES, INC. $2,423,338 Construction Manager as Constructor at Risk services to renovation Building 10, F Wing in two phases: Phase A of the F Wing Renovation: Pre construction, construction, activation/occupancy and closeout; to convert 64,000 gsf of former patient care units o
This spending item is part of a $131,640,100 allocation. See details
National Institutes of Health 7/30/2010
UNIVERSITY OF MARYLAND $2,348,664 To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders.
This spending item is part of a $10,496,230 allocation. See details
National Institutes of Health 7/13/2009
JOHNS HOPKINS UNIVERSITY, THE $2,144,292 Trans-NIH Recovery Act Research Support iPS Cells As Models of ALS: To gain an understanding of the mechanisms underlying any given disease requires access to relevant cell classes on the same genetic background. Although ALS research has seen significant advances over recent years, this precon
This spending item is part of a $3,782,000 allocation. See details
National Institutes of Health 9/28/2009
American Medical Association $2,087,617 ARRA - Health Information Technology Extension Program This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance and information on best practices to support and accelerate health care providersG?? eff... Show more
This spending item is part of a $6,874,318 allocation. See details
Health and Human Services, Department of 3/30/2010
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $2,000,000 Trans-NIH Recovery Act Research Support We propose to acquire a 16.4 Tesla wide-bore vertical magnetic resonance (MR) small- animal scanner equipped with multi-coil receive capability. The overall goal is to upgrade the F.M. Kirby Research Center at the Kennedy Krieger Institute (KKI) to a st National Institutes of Health 4/28/2009
JOHNS HOPKINS UNIVERSITY, THE $1,976,376 Trans-NIH Recovery Act Research Support Project objective: This project will perform annual cognitive evaluations on subjects previously enrolled in the Alzheimer's Disease Anti-Inflammatory Protection Trial (ADAPT). The purpose of these evaluations is to extend observations on the ADAPT outc
This spending item is part of a $5,985,586 allocation. See details
National Institutes of Health 8/12/2009
JOHNS HOPKINS UNIVERSITY, THE $1,962,887 Trans-NIH Recovery Act Research Support This application is in response to RFA number RFA-OD-10-005 and addresses thematic area 1: Applying genomics and other high throughput technologies. Retrotransposons are an often-overlooked source of inter-individual genomic variation in mammals. The prim
This spending item is part of a $2,078,635 allocation. See details
National Institutes of Health 9/27/2010
MD ST DEPARTMENT OF HUMAN RESOURCES $1,943,884 Foster Care_Title IV-E FY 2011 FOSTER CARE Administration for Children and Families 1/01/2011
UNIVERSITY OF MARYLAND $1,937,551 Trans-NIH Recovery Act Research Support Overweight is a serious public health problem that begins as early as toddlerhood, and has negative health and developmental consequences throughout life. Although caregiver-child interaction patterns influence children's growth, most overweight preventio
This spending item is part of a $2,010,457 allocation. See details
National Institutes of Health 9/30/2009
BALTIMORE CITY HEAD START $1,914,720 ARRA - Head Start 1) American Recovery and Reinvestment Act (ARRA). The award provides for a 3.06% permanent COLA and 1.84% temporary COLA as well as for quality improvement funding. Baltimore City Head Start's ?Quality Improvement? (QI) funds address three areas that w Administration for Children and Families 6/23/2009
JOHNS HOPKINS UNIVERSITY, THE $1,820,000 ARRA - Health Information Technology Professionals in Health Care ARRA Health Information Technology Professionals in Health Care: Curriculum Development Centers. This award will fund the development of six to 12 month informatics curriculum for deployment at Community Colleges throughout the U.S. Th... Show more Health and Human Services, Department of 4/02/2010
BALTIMORE MEDICAL SYSTEM, INC. $1,806,360 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Captial Improvement Program:Our 4 projects will increase service capacity, effectiveness, efficiency, quality of care, and patient outcomes: a Renovation project (pharmacy space), a Construction project (expansion of a health ce... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF MARYLAND $1,720,671 Trans-NIH Recovery Act Research Support The muscular dystrophies are complex genetic diseases characterized by inherited or sporadic defects in genes that encode muscle proteins. Although Duchenne (DMD), Becker, limb girdle, congenital, facioscapulohumeral, myotonic, oculopharyngeal, distal, an
This spending item is part of a $2,204,914 allocation. See details
National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $1,698,862 Trans-NIH Recovery Act Research Support High-throughput screen for FDA approved drugs that amplify Beta-cell mass in vivo The aim of the project proposed here is to identify drugs that will be therapeutic in the treatment of Diabetes. Type I (or Juvenile) Diabetes is caused by a chronic loss of
This spending item is part of a $2,524,394 allocation. See details
National Institutes of Health 9/30/2010
UNIVERSITY OF MARYLAND $1,692,864 Trans-NIH Recovery Act Research Support This application addresses the National Center on Minority Health and Health Disparities' (NCMHD's) Social Determinants of Health Initiative high priority area for funding under the NIH Research and Research Infrastructure Grand Opportunity. The project i
This spending item is part of a $2,488,503 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $1,641,434 Trans-NIH Recovery Act Research Support 'The Study to Help the AIDS Research Effort (SHARE) was funded by NIAID and NCI in 1983 to study the natural history of infection with human immunodeficiency virus, type 1 (HIV). SHARE, along with similar sites in Chicago, Pittsburgh, and Los Angeles, for National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $1,632,174 Trans-NIH Recovery Act Research Support This Faculty Development Research Core will recruit Dr. Julius Birnbaum and Dr. Ami Shah to the tenure track faculty as Assistant Professors in the Division of Rheumatology at Johns Hopkins University. The Division of Rheumatology at Johns Hopkins is a hi National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $1,602,344 Trans-NIH Recovery Act Research Support Identification of Genes Causing Familial Crohn?s Disease. Nearly 500,000 Americans, both children and adults, have Crohn?s disease, and in approximately one-quarter of those affected, two or more family members have the disease. People of Jewish ancestry
This spending item is part of a $1,640,420 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $1,591,641 Trans-NIH Recovery Act Research Support Persons with abdominal obesity have a high prevalence of endothelial dysfunction, arterial stiffness, and left ventricular diastolic function, each an early marker of cardiovascular disease (CVD). Though diet and exercise are primary treatments for obesit National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $1,549,856 Trans-NIH Recovery Act Research Support Sickle cell disease (SCD) is one of the most common inherited diseases in the United States. Vasocclusion, resulting in acute, debilitating pain, is the hallmark of SCD often necessitating hospitalization. In part due to SCD patients? need for narcotic me National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $1,502,938 Trans-NIH Recovery Act Research Support The University of Maryland Baltimore is submitting this application to establish a Bioethics Center under the NCMHD ARRA Scientific priority area 'Bioethics Research Infrastructure Initiative' through 'GO' grants RFA-OD-09-004. This Bioethics Center's pro
This spending item is part of a $2,425,363 allocation. See details
National Institutes of Health 9/27/2009
UNIVERSITY OF MARYLAND $1,500,000 Trans-NIH Recovery Act Research Support The mission of the University of Maryland Marlene and Stewart Greenebaum Cancer Center is to undertake innovative basic and clinical research which will impact the understanding and treatment of cancer around the world and to provide state-of-the-art clin National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $1,435,514 Trans-NIH Recovery Act Research Support Genetic Determinants of Premature Vascular Dysfunction in Families: This is a study to find the genes responsible for prematurely stiff and unresponsive arteries. The study is done in families with a risk of early heart attacks. National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $1,430,723 Trans-NIH Recovery Act Research Support The award 'Predicting pancreatic cancer responses for a Parp inhibitor-based clinical trial' is part of a larger effort by our group to identify the genetic basis of pancreatic cancer and to use that information to develop personalized therapies to fight
This spending item is part of a $1,912,026 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $1,428,909 Trans-NIH Recovery Act Research Support Improving our understanding of gene-environment interaction (GxE) as an etiologic mechanism in autism has been identified as a research priority in the NIH Inter-Agency Autism Coordinating Committee's (IACC's) Strategic Plan for Autism Spectrum National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $1,423,454 Trans-NIH Recovery Act Research Support ARRA: BIOMARKER PREDICTION OF GLEASON UPGRADING Over treatment of prostate cancer (treatment that does not extend lifespan) has increased dramatically with the advent of PSA testing. Active surveillance (AS) is an approach to reduce over treatment by care
This spending item is part of a $1,956,421 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $1,413,300 Trans-NIH Recovery Act Research Support The Johns Hopkins University AIDS Clinical Trials Unit (CTU) will bring together three independently funded HIV clinical research groups that perform (1) adult and (2) pediatric treatment trials, and (3) HIV prevention research. These three groups will fo National Institutes of Health 9/01/2009
JOHNS HOPKINS UNIVERSITY, THE $1,410,090 Trans-NIH Recovery Act Research Support The leading causes of Type 2 diabetes and prediabetes are being overweight or obese and being sedentary. Diabetes and prediabetes have adverse effects on parameters of cardiac and peripheral vascular structure and function that precede clinical manifestat National Institutes of Health 6/21/2009
JOHNS HOPKINS UNIVERSITY, THE $1,386,779 Recovery Act Comparative Effectiveness Research - AHRQ In this project we seek to utilize our successful experience in computer-assisted patient education in order to develop a comprehensive informatics framework for rapid adaptation and dissemination of Comparative Effectiveness Research (CER) produ... Show more Agency for Healthcare Research and Quality 8/31/2010
JOHNS HOPKINS UNIVERSITY, THE $1,383,412 Trans-NIH Recovery Act Research Support The project titled ?Alcohol sensitivity and PET derived measures of opioid activity? investigates whether differences in opioid activity may contribute to individual differences in alcohol sensitivity and ultimately to development of alcohol use disorders National Institutes of Health 9/03/2009
JOHNS HOPKINS UNIVERSITY, THE $1,369,510 Trans-NIH Recovery Act Research Support Hearing plays an important role in the normal development of brain structure and function. Previous work supported by this grant has shown that hereditary congenital deafness in cats results in abnormal synaptic structure in auditory nerve terminals, and National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $1,364,612 Trans-NIH Recovery Act Research Support Increasing amounts of sequence data are being generated in multiple biomedical research disciplines, particularly through the application of next-generation sequencing technologies to the genomic analysis of humans and their associated microbiome. However National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $1,313,450 ARRA - Strategic Health IT Advanced Research Projects (SHARP) The Strategic Healthcare IT Advanced Research Projects on Security (SHARPS) project will advance the sophistication, development, and deployment of security and privacy for Health Information Technology (HIT) through long-term research tha... Show more
This spending item is part of a $15,000,000 allocation. See details
Health and Human Services, Department of 3/19/2010
UNIVERSITY OF MARYLAND $1,298,153 Trans-NIH Recovery Act Research Support In the current year more than 1.5 million new cancer cases will be diagnosed (American Cancer Society, 2008) and nearly 11 million Americans have a history of cancer. The annual costs for medical care for patients with cancer was an estimated $219 billion National Institutes of Health 8/16/2010
UNIVERSITY OF MARYLAND $1,285,578 Trans-NIH Recovery Act Research Support We propose to determine on a genome-wide and population-wide scale genetic variations across all major diarrheal and extra-intestinal E. coli pathotypes, with the analysis of positive selection footprints in genes shared by multiple strains. The main fo
This spending item is part of a $4,030,115 allocation. See details
National Institutes of Health 9/29/2010
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $1,258,613 ARRA - Preventing Healthcare-Associated Infections The ELC program will coordinate and implement HAI prevention activities and report on progress toward reductions in two or more HHS Action Plan Targets. This will include: G?? State HAI Plan coordinator identified; G?? Multidisciplinary group convene... Show more Centers for Disease Control and Prevention 8/28/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $1,258,613 ARRA - Preventing Healthcare-Associated Infections The ELC program will coordinate and implement HAI prevention activities and report on progress toward reductions in two or more HHS Action Plan Targets. This will include: G?? State HAI Plan coordinator identified; G?? Multidisciplinary group convene... Show more Centers for Disease Control and Prevention 8/28/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $1,209,764 Adoption Assistance FY 2011 ADOPTION ASSISTANCE Administration for Children and Families 3/25/2011
JOHNS HOPKINS UNIVERSITY, THE $1,190,461 Trans-NIH Recovery Act Research Support This is a two-year AARA grant application that is aimed to develop, construct, and evaluate a prototype SPECT/MRI system for simultaneous high-resolution molecular SPECT/MR imaging of small animals, with the potential of further development into a human b National Institutes of Health 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $1,182,171 Trans-NIH Recovery Act Research Support Pathogenesis of glaucomatous optic nerve damage is the funded project title. The project studies how the disease glaucoma causes blindness in human eyes and uses animal models in rats and mice to study both how the disease damages the eye's tissues a National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $1,179,721 Trans-NIH Recovery Act Research Support Understanding Disparities In Obesity and Its Comorbidities In the U.S: The study is a systematic investigation to understand the individual-, family-, and community-level causes of ethnic/SES disparities in obesity and its comorbidities including type 2 d National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $1,156,662 Trans-NIH Recovery Act Research Support The long term objectives of this research are to identify the mechanisms of neuromechanical (NM) impairments underlying postural balance dysfunction in older people, and to establish a scientifically grounded therapeutic program for enhancing balance func National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $1,150,015 Trans-NIH Recovery Act Research Support Malaria kills over one million people each year. Most malaria deaths occur in Africa and most of the victims are children under five. An effective, affordable vaccine would greatly reduce the morbidity, mortality, and economic burden imposed by malaria. W National Institutes of Health 5/29/2009
TOTAL HEALTH CARE, INC. $1,126,540 Project 1: Alteration/Repair/Renovation, with/ without IT Equipment DENTAL CONSTRUCTION The current Dental Suite will expand by approximately 550 square feet to 2,665 square feet total. The additional space will be recouped by relocating three (3) ad Health Resources and Services Administration 6/25/2009
TOTAL HEALTH CARE, INC. $1,126,540 ARRA Health Center Integrated Services Development Initiative[g1] Narrative Summary Project 1: Alteration/Repair/Renovation, with/ without IT Equipment DENTAL CONSTRUCTION The current Dental Suite will expand by approximately 550 square feet to 2,665 square feet total. The additional space will... Show more Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS UNIVERSITY, THE $1,103,855 ARRA - Preventive Medicine Residency Program ARRA-Preventive Medicine Residency Program - This project will set its objectives to meet the goals of the Bureau of Health Professions (BHPr) of HRSA which are: I) To improve access to quality health care through appropriate preparation, composition, and... Show more Health Resources and Services Administration 7/01/2010
JOHNS HOPKINS UNIVERSITY, THE $1,045,498 Trans-NIH Recovery Act Research Support The Go grant award funded a 2-year research project investigating a new modality of therapy directed at memory impairment in the elderly. Aging is often associated with cognitive deficits, especially decline in memory functions that depend on the structur
This spending item is part of a $1,332,400 allocation. See details
National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $1,043,591 Trans-NIH Recovery Act Research Support The supplement has funded the establishment of an SIV/Macaque Research Core which will provide the expertise to evaluate novel therapeutics and surrogate markers to develop new therapies for HIV-associated neurocognitive disorders. The investigators have National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $1,000,000 Trans-NIH Recovery Act Research Support Our project is entitled 'Comparison of Novel Technologies to Improve Early Identification of Preclinical Coronary Atherosclerosis in High Risk Families.' Its prime purpose is to compare an innovative coronary artery imaging technology with a standard imag National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $999,974 Millions of patients will be treated for cancer this year. Physicians require a mechanism through which the efficacy of chemotherapeutic treatment can be monitored. While measuring tumor size is important, size may change more slowly than tumor functional National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $999,956 Trans-NIH Recovery Act Research Support The overarching goal of this proposal is to characterize the mechanisms through which SDB may lead to alterations in glucose metabolism and determine the putative role of ET-1. To accomplish our goals, we will employ a combination of unique observational National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $999,578 Trans-NIH Recovery Act Research Support Development of low cost and broadly protective human papillomavirus vaccines. HIV+ patients exhibit more severe and progressive human papillomavirus (HPV) infections than HIV- individuals, and consequently cervical cancer has been designated an HIV-associ National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $998,214 Trans-NIH Recovery Act Research Support This application addresses the development of technologies for assessment of aortic aneurysms prone to rupture or dissection In the current proposal we address a clinically relevant and pressing need to elucidate the mechanisms that (i) would enable us to National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $997,851 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (07) Enhancing Clinical Trials and specific Challenge Topic, 07-DK-103: Support for Registries. Live donor kidney transplantation is the best treatment for kidney failure, doubling life expectancy and signif National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $997,753 Trans-NIH Recovery Act Research Support This grant addresses Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic, 03-HL-101 and is entitled, ?Biomarkers of Sudden Death and Progressive Heart Failure?. More than 5 million people in the United States alone have adv National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $997,006 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic 06-HG-103: Methods to sequence highly variable, repeat-rich regions of complex genomes. A remarkable 45% of our genome consists of repetitive elements National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $995,182 Trans-NIH Recovery Act Research Support This project, entitled ?Epidemiology and Mechanisms of Accelerated Aging in HIV Infection,? addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-AI-101: Accelerated Aging in Treated vs. Untreated HIV/AIDS National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $993,692 Trans-NIH Recovery Act Research Support Although the AIDS epidemic is nearly 30 years old, and HIV infection can generally be held in check with modern drug cocktails, Kaposi?s Sarcoma (KS), one of the original AIDS-defining opportunistic infections, is now the leading cancer reported in Southe National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $985,802 Trans-NIH Recovery Act Research Support This proposal is called: A Vision of Hope: Integration of Palliative Care in Chronic Pediatric Disease. The project is directly responsive to the specific challenge topic, Methods to Enhance Palliative Care and End-of-Life Research. It is designed to impr National Institutes of Health 9/23/2009
UNIVERSITY OF MARYLAND $984,910 Trans-NIH Recovery Act Research Support Lymphocytes bearing high levels of FasL are known to suppress cell-mediated immunity and destroy the efficacy of DNA vaccines. Their ability to kill the antigen-presenting cells can be eliminated by several different mechanisms and we are exploring a numb National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $984,000 Trans-NIH Recovery Act Research Support Alzheimer?s Disease (AD), the most common cause of dementia in the elderly, is characterized by the deposition of amyloid plaque and neurofibrillary tangles in the brain. Despite significant advances made toward our understanding of the pathogenesis of AD National Institutes of Health 8/04/2009
JOHNS HOPKINS UNIVERSITY, THE $983,640 Trans-NIH Recovery Act Research Support Improving Care Continuity in Drug Abuse Treatment Drug users generally benefit from continuing treatment in an outpatient program following their stay in a residential treatment setting. This project will set up linkages between residential and outpatient National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $982,190 Trans-NIH Recovery Act Research Support We submit this proposal in response to RFA-OD-09-004 'Grand Opportunities (GO)' and NHLBI requests for applications to one of its 9 selected high-priority topics, 'Characterizing Differentiated Heart, Lung, and Blood Cells Derived by Reprogramming Human E
This spending item is part of a $1,251,292 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $978,862 Trans-NIH Recovery Act Research Support Needle biopsy is a regularly performed procedure required for diagnosing prostate cancer (PC). An estimated 1.3 million biopsies are performed yearly in the US at a healthcare cost of $2.6 billion. Biopsies are typically triggered by elevated prostate spe National Institutes of Health 9/24/2009
FRIENDS RESEARCH INSTITUTE, INC $977,169 Trans-NIH Recovery Act Research Support With greater availability of evidence-based practices in the drug abuse field, specifically, for offender clients, it is crucial that we develop strategies that allow for the adoption, implementation and sustaining of aids to effective clinical practice. National Institutes of Health 7/14/2009
UNIVERSITY OF MARYLAND $971,364 Trans-NIH Recovery Act Research Support The purpose of the proposed studies is to evaluate a novel combination treatment in experimental traumatic brain injury (TBI). Traditional treatment strategies for TBI aim to prevent delayed neuronal cell death by inhibiting one proposed cell death mechan National Institutes of Health 11/19/2009
JOHNS HOPKINS UNIVERSITY, THE $961,655 Trans-NIH Recovery Act Research Support Maximizing Effectiveness of Integrated Treatment Approaches. The present study uses behavioral reinforcement to motivate opioid dependent patients with any co-occurring psychiatric disorder to attend scheduled psychiatric appointments and mental health co National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $958,863 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (05): Comparative Effectiveness Research and specific Challenge Topic 05-DA-102: Treatment of Substance Abuse and Related Health Consequences Using Web-Based Technologies. Web-based videoconferencing technol National Institutes of Health 9/30/2009
FRIENDS RESEARCH INSTITUTE, INC $945,541 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (05): Comparative Effectiveness Research, and specific Challenge Topic (05-DA-104): Comparing Drug Treatment Effectiveness in Ethnic Minority Populations Background: Although there is relatively little diffe
This spending item is part of a $990,091 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $930,338 Trans-NIH Recovery Act Research Support The development of hormone resistance in breast cancer is a significant clinical problem. The enhanced expression of the ErbB2/3 heterodimer leads to the ability of breast cancer cells to bypass normal endocrine responsiveness. However, the use of ErbB2 t National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $924,643 Trans-NIH Recovery Act Research Support Idiopathic (primary) pulmonary artery hypertension in children or adults (IPAH) is a progressive and fatal disease characterized by sustained elevations of pulmonary artery pressure of unknown etiology. Vasodilators are the mainstay of therapy, however 20 National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $918,199 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics Topic: 08-DE-103: Epigenomics and Epigenetics of Oral Health and Disease. The standard paradigm for characterization of genome wide epigenetic alteration in human cancers has been focused on di National Institutes of Health 9/22/2009
UNIVERSITY OF MARYLAND $908,409 Trans-NIH Recovery Act Research Support Essential hypertension is a major threat to public health, affecting over a billion people in the world and contributing to kidney and cardiovascular mortality and morbidity in 5 million people annually. Like other complex disorders, multiple genes with v
This spending item is part of a $999,876 allocation. See details
National Institutes of Health 9/25/2009
MARYLAND STATE DEPARTMENT OF HEALTH & MENTAL $906,007 Medical Assistance Program MEDICAID ENTITLEMENT FOR MARYLAND - FY 2012 QUARTER 1 - T19 Health Care Financing Admin. (was Medicare and Medicaid Serv.) 12/27/2011
JOHNS HOPKINS UNIVERSITY, THE $901,280 Trans-NIH Recovery Act Research Support Comparative effectiveness research is an evaluation of the effectiveness and harms of treatment options available for a given health condition. Multiple treatment comparison (MTC) meta-analysis is a meta-analysis technique attracting growing interest beca National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $892,864 Trans-NIH Recovery Act Research Support Notch signaling in mammalian neural progenitors, this work will contribute to the treatment of nervous system disorders, including brain cancer and neurodegenerative diseases, and to the treatment of traumatic brain injury. National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $891,083 Trans-NIH Recovery Act Research Support In this two-year AARA grant application, we propose to continue our investigation into 4D image reconstruction methods to further improve the quality and quantitative accuracy of 4D gated myocardial perfusion (GMP) emission computed tomography (ECT) inclu National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $889,637 Trans-NIH Recovery Act Research Support Poor adherence to medication regimens is associated with worsening of disease, death and increased health care costs in the United States. The few studies conducted in the emergency department (ED) setting suggest that between 7 to 45 percent of patients
This spending item is part of a $959,827 allocation. See details
National Institutes of Health 8/19/2010
JOHNS HOPKINS UNIVERSITY, THE $888,930 Trans-NIH Recovery Act Research Support Research and Treatment in Comparative Effectiveness, Quality Improvement (QI) and Investigational New Drugs (IND) Research examines the research-treatment interface in the context of traditional clinical trials, comparative effectiveness research, and qua
This spending item is part of a $971,784 allocation. See details
National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $884,760 Trans-NIH Recovery Act Research Support Apathy in Alzheimer's dementia (AD) is a significant public health problem with serious adverse consequences for patients and caregivers. Apathy affects approximately 70% of AD patients, making it one of the most common neuropsychiatric symptoms (M. S. Me
This spending item is part of a $1,449,988 allocation. See details
National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $865,647 Recovery Act Comparative Effectiveness Research - AHRQ The program will prepare doctorally-trained individuals, including physicians, for academic careers of scholarship in CER targeted for quality improvement, patient/family-centered care, and health/health care disparities, focusing on the needs of... Show more Agency for Healthcare Research and Quality 9/01/2010
UNIVERSITY OF MARYLAND $860,237 Trans-NIH Recovery Act Research Support This application addresses broad the Challenge Area (06) Enabling Technologies and Specific Challenge Topic 06-GM-106; subcellular imaging of metal ions. Methods to improve spatial resolution are complex and not always compatible with cell imaging. For ex National Institutes of Health 9/28/2009
UNIVERSITY OF MARYLAND $850,866 Trans-NIH Recovery Act Research Support The long-term goal of this project is to identify novel monoclonal antibodies (mAbs) that broadly recognize the HIV-1 envelope glycoprotein (Env) and block infection in vitro to guide vaccine development. This goal will be pursued in a cohort of HIV-1 inf National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $838,278 Trans-NIH Recovery Act Research Support Abstract The purpose of this application is to enhance both the process and benefits of clinical and translational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying o National Institutes of Health 9/09/2009
JOHNS HOPKINS UNIVERSITY, THE $836,133 Trans-NIH Recovery Act Research Support The Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to characterize the natural history of the different phenotypes of nonalcoholic fatty liver National Institutes of Health 9/30/2010
JOHNS HOPKINS UNIVERSITY, THE $835,745 Trans-NIH Recovery Act Research Support Progression of Dementia: A Population Study (R01AG21136) The Cache County Dementia Progression Study (DPS; R01AG21136) has been funded from NIA since 2002, and with the current ARRA award, will be extended through 2012, a one-year no cost extension. This
This spending item is part of a $2,993,593 allocation. See details
National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $833,417 Trans-NIH Recovery Act Research Support Schizophrenia is a devastating psychiatric illness arising in part from subtle defects in brain development. The Disrupted-In-Schizophrenia-1 (DISC1) gene is an example of a strong candidate gene for studying the pathogenesis of schizophrenia and associat National Institutes of Health 5/15/2009
JOHNS HOPKINS UNIVERSITY, THE $832,418 Trans-NIH Recovery Act Research Support Recovery Act funds have been awarded for the study of 'Effects of sex and fat distribution on sleep disordered breathing'. This award will support two additional senior faculty members (total of 25% effort ), two new junior faculty (30% effort) and techni National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $831,106 Trans-NIH Recovery Act Research Support Recovery Act funds have been awarded for the study of ?Angiogenesis in the Lung?. This award continues to partially supports two full time faculty members. The work is focused on determining mechanisms of neovascularization in the lung. Excessive systemic National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $823,369 Technical support and administrative/management services: Task Order 6, Antiviral and Immune Plasma Infrastructure Development
This spending item is part of a $12,962,657 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $822,913 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic (04-HL- 103): Assess the role of leukocyte interactions with platelets, erythrocytes, and endothelium in the pathogenesis of heart, lung, and blood disease National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $820,000 Trans-NIH Recovery Act Research Support We previously described a naturally occurring mutation (Nuc1) in the Sprague-Dawley rat with a novel and unusual eye phenotype. Nuc1 is inherited as a single Mendelian locus with viable homozygotes and an intermediate phenotype in heterozygotes. The mutat National Institutes of Health 6/19/2009
JOHNS HOPKINS UNIVERSITY, THE $811,834 Trans-NIH Recovery Act Research Support With the increase in obesity and diabetes, other chronic diseases are also increasing. Nonalcoholic fatty liver disease (NAFLD) is one such disease that has potentially enormous public health consequences. NAFLD is a leading cause of chronic liver disease National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $810,357 Trans-NIH Recovery Act Research Support The overall propose is to understand the initial steps in stem cell differentiation. The expected outcome is to learn more information that will allow us to i) develop new markers to allow us to classify and purify unique populations of stem cell, ii) ide National Institutes of Health 6/08/2009
JOHNS HOPKINS UNIVERSITY, THE $810,001 Trans-NIH Recovery Act Research Support It is clear that the tissue microenvironment plays a critical role in regulating inflammation and tissue destruction. Chronic inflammation and tissue fibrosis lead not only to increased turnover of the extracellular matrix but also to an increase in infla National Institutes of Health 5/30/2009
FAMILY HEALTH CENTERS OF BALTIMORE $808,985 ARRA Health Center Integrated Services Development Initiative[g1] A construction project will re-locate the Brooklyn satellite office to a larger more centrally located facility that is now an empty furniture store, in the middle of the Brooklyn community and on a bus line. The proposed site is more... Show more Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS UNIVERSITY, THE $807,497 Trans-NIH Recovery Act Research Support This project is to investigate the mechanism of activation of the interferon regulatory factor (particularly IRF-3) following virus infection.-? The activation of IRFs, which is triggered by the phosphorylation of certain Ser/Thr residues, results in its National Institutes of Health 5/07/2009
JOHNS HOPKINS UNIVERSITY, THE $805,604 Trans-NIH Recovery Act Research Support This award funds the project titled: ?Chronic hypoxia and pulmonary vascular smooth muscle?. The funded activity includes conducting experiments aimed at characterizing the effects of prolonged exposure to hypoxia on pulmonary arterial smooth muscle cells National Institutes of Health 5/30/2009
JOHNS HOPKINS UNIVERSITY, THE $804,640 Trans-NIH Recovery Act Research Support Mosquitoes utilize a variety of strategies to combat pathogens, including viruses. The long term_ goal of the PIs research is to elucidate, at the molecular level, the immune responses of the mosquito vector Aedes aegypti to infection with a range of vira National Institutes of Health 8/14/2009
UNIVERSITY OF MARYLAND $802,606 Trans-NIH Recovery Act Research Support The motor cortex of all mammalian species, including humans, contains a gross somatotopic representation of the major divisions of the body, such as hindlimb, forelimb, and face. Within each body part, there are multiple, non-contiguous, partially overlap National Institutes of Health 7/20/2009
JOHNS HOPKINS UNIVERSITY, THE $802,169 Trans-NIH Recovery Act Research Support The title of this project is Improving Childhood Immunization Compliance Using Electronic Health Records. This application addresses broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-LM-103: Improving Compliance National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $799,884 Trans-NIH Recovery Act Research Support Asthma affects over 17 million people in the United States, and is a significant cause of morbidity. Development of novel therapies to reduce asthma burden is a major priority of the scientific community, yet such studies are often hampered by the limited
This spending item is part of a $8,346,809 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF MARYLAND $799,496 Trans-NIH Recovery Act Research Support We propose an innovative approach to designing and conducting randomized clinical trials (RCTs) for comparative effectiveness research (CER). Evidence from 'pragmatic' RCTs can inform real-world decisions by comparing clinically relevant alternatives acro
This spending item is part of a $1,499,866 allocation. See details
National Institutes of Health 9/23/2010
JOHNS HOPKINS UNIVERSITY, THE $798,135 Trans-NIH Recovery Act Research Support This award was funded to support our ongoing effort to develop MRI image analysis software, called DtiStudio/MriStudio. This is a family of software to analyze MR images. The software was developed through collaboration between Drs. Mori and Miller and it National Institutes of Health 7/20/2009
JOHNS HOPKINS UNIVERSITY, THE $793,510 Trans-NIH Recovery Act Research Support ?Redox signaling in axon guidance: Structure and activity of MICAL? During neural development, axons are guided to their final destination by a large number of molecular cues?attractive and repulsive signals that instruct the cytoskeleton to redirect the National Institutes of Health 6/15/2009
PARK WEST HEALTH SYSTEMS INCORPORATED $790,575 ARRA Health Center Integrated Services Development Initiative[g1] The grant award received by Park West Health Systems, grant number C81CS1380,is being utilized to implement Electronic Medical Records (EMR) at each of the organization's four locations. Implementing EMR allows Park West to serve their... Show more Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS UNIVERSITY, THE $780,538 Trans-NIH Recovery Act Research Support The overarching goal of this Competitive Revision [Notice Number (NOT-OD-09-058) and Notice Title (?NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications?)] is to expand the scope of our current grant, ?In-Home Prevent National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $780,310 Trans-NIH Recovery Act Research Support HIV infection in the US occurs disproportionately among racial/ethnic minority youth in urban areas. The Adolescent Trials Network for HIV/AIDS Interventions (ATN) has developed a community-based primary HIV prevention infrastructure in 13 cities anchored
This spending item is part of a $6,833,921 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $776,646 Trans-NIH Recovery Act Research Support Project objective: This project will perform annual cognitive evaluations on subjects previously enrolled in the Alzheimer's Disease Anti-Inflammatory Protection Trial (ADAPT). The purpose of these evaluations is to extend observations on the ADAPT outc
This spending item is part of a $5,985,586 allocation. See details
National Institutes of Health 8/12/2009
EDUCATION, MARYLAND DEPARTMENT OF $773,757 ARRA - Head Start The Early Childhood Advisory Council is on track with progress toward the goals of the Council's Action Plan, Year Two. Here are some of the activities and outcomes for this reporting period: G?? Completed the Early Childhood Task Force on Transition:
This spending item is part of a $1,060,163 allocation. See details
Administration for Children and Families 8/24/2010
TOTAL CHILD HEALTH, INC. $767,637 Trans-NIH Recovery Act Research Support The study's purpose is a cost-effectiveness study taking advantage of data from a large cohort derived from universal school screening for symptoms of ADHD collected by a web-based decision support system. Said system, called CHADIS, collects data from pa
This spending item is part of a $998,780 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF MARYLAND $750,780 Trans-NIH Recovery Act Research Support Human ether a go-go-related gene 1a (HERG1a, Kv11.1) K+ channels play a critical role in maintaining the fundamental cardiac rhythm. The significance of HERG1a channels is that they are the central component of the rapid delayed-rectifier K+ channel (IKr) National Institutes of Health 6/21/2009
UNIVERSITY OF MARYLAND $750,000 Trans-NIH Recovery Act Research Support Associative learning is supported by the ability to recognize errors between expected and actual outcomes. Evidence from primate and rat recording studies suggests that dopaminergic neurons in substantia nigra and the ventral tegmental area (VTA) signal s National Institutes of Health 6/08/2009
UNIVERSITY OF MARYLAND $750,000 Trans-NIH Recovery Act Research Support Pathogenic bacteria require iron for their survival and ability to cause infection. Heme comprises 90% of the iron available within the host and plays a significant role in the colonization and virulence of many bacterial pathogens. Shigella spp. and ente National Institutes of Health 8/01/2009
UNIVERSITY OF MARYLAND $750,000 Trans-NIH Recovery Act Research Support Insults to the brain and spinal cord result not only in debilitating motor, sensory and cognitive deficits, but also in chronic, excruciating and relentless pain that is largely resistant to treatment. In most patients, pain starts weeks or months after t National Institutes of Health 9/20/2009
UNIVERSITY OF MARYLAND $750,000 Trans-NIH Recovery Act Research Support Type 1 interferons (IFNs) were discovered as mediators of host antiviral functions, and were recently shown to play essential roles in the innate immune response to nonviral pathogens. Established effectors of IFN antiviral action may thus serve previousl National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $749,337 Trans-NIH Recovery Act Research Support This application responds to NHLBI Participation in Research and Research Infrastructure 'Grand Opportunities' (RC2) (RFA-OD-09-004) for Large-scale DNA Sequencing and Molecular Profiling of Well-Phenotyped NHLBI Cohorts. The major goal of this proposal
This spending item is part of a $5,155,213 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $737,205 Trans-NIH Recovery Act Research Support Three randomized trials, including one which is the basis for this proposal, and numerous observational studies demonstrate that male circumcision reduces male HIV acquisition. We conducted an NIH-funded trial of male circumcision for HIV prevention in ru National Institutes of Health 9/21/2009
TOTAL CHILD HEALTH, INC. $736,462 Trans-NIH Recovery Act Research Support The study's purpose is a cost-effectiveness study taking advantage of data from a large cohort derived from universal school screening for symptoms of ADHD collected by a web-based decision support system. Said system, called CHADIS, collects data from pa
This spending item is part of a $998,780 allocation. See details
National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $732,880 Trans-NIH Recovery Act Research Support Glaucoma is the second leading cause of blindness in the United States. Understanding how retinal ganglion cell (RGC) susceptibility to degeneration is modulated by the major risk factor, elevation of intraocular pressure (IOP), as well as other factors, National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $720,369 Trans-NIH Recovery Act Research Support Obesity is a major public health concern: the prevalence of obesity in the US has increased dramatically, reaching rates greater than 30%. Although lifestyle and pharmacological therapies are successful in the short term, subsequent regain of lost weight National Institutes of Health 7/28/2010
UNIVERSITY OF MARYLAND $702,919 Trans-NIH Recovery Act Research Support This NIH Challenge Grant application addresses the specific Challenge Area (05): Comparative Effectiveness Research, and the specific Challenge Topic, 05-CA-104: Comparative Effectiveness Research in Cancer Treatment. This study will examine patterns of t
This spending item is part of a $773,678 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $688,765 Trans-NIH Recovery Act Research Support This application addresses Grand Opportunity: Phase 2 Clinical Trials Program of Novel Therapies for HLB Diseases. Obstructive sleep apnea (OSA) afflicts > 5% of adults and is associated with a 2 to 4-fold increased risk of cardiovascular disease (CVD). D
This spending item is part of a $3,126,139 allocation. See details
National Institutes of Health 9/07/2010
UNIVERSITY OF MARYLAND $688,151 Trans-NIH Recovery Act Research Support Alcoholism and anxiety frequently co-occur in humans; however, it has been difficult to find a single treatment which is effective against both conditions. Substantial evidence suggests that the motivational aspects of alcohol withdrawal (e.g., increased
This spending item is part of a $753,174 allocation. See details
National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $680,600 Trans-NIH Recovery Act Research Support The Role of MicroRNA Alterations in Barrett?s Carcinogenesis: Patients with Barrett?s esophagus (BE) are at increased risk of developing esophageal adenocarcinoma (EAC), one of the most rapidly increasing cancers in developed nations. The molecular geneti National Institutes of Health 8/11/2009
UNIVERSITY OF MARYLAND $675,000 Trans-NIH Recovery Act Research Support The serine proteases are the pivotal regulators of a variety of cellular processes critical for normal homeostasis. In the gut, host intestinal serine proteases not only control digestion, but their unregulated activities contribute to the pathogenesis of National Institutes of Health 7/20/2009
PEOPLE'S COMMUNITY HEALTH CENTER, INC., THE $664,785 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Project. Expansion of service capacity through renovation of two PCHC practice locations: 5517 Ritchie Highway, Anne Arundel County, MD 21225 and 1111 Washington Boulevard, Baltimore, MD 21230. The Capital Impro... Show more Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS UNIVERSITY, THE $664,660 Trans-NIH Recovery Act Research Support Mucus Penetrating Nanoparticles for Early Stage Cervical Cancer: Drugs administered systemically typically reach the cervicovaginal (CV) tract in very low concentrations. As a result, drug therapies for diseases that affect the CV tract typically suffer f National Institutes of Health 5/21/2009
HEALTH CARE FOR THE HOMELESS, INC. $660,585 ARRA Health Center Integrated Services Development Initiative[g1] ARRA Capital Improvement Program: Health Care for the Homeless submitted a bi-partite proposal for CIP funds. Construction/Equipment funds were requested to purchase an emergency back-up generator and signage for our new building. The... Show more Health Resources and Services Administration 6/29/2009
JOHNS HOPKINS UNIVERSITY, THE $656,000 Trans-NIH Recovery Act Research Support During early development of the mammalian eye, there is a transient network of blood vessels arising from the area of the optic nerve, extending through the vitreous, and surrounding the developing lens. Called the fetal vasculature, these blood vessels n National Institutes of Health 9/16/2009
CHASE BREXTON HEALTH SERVICES, INC $654,005 ARRA Health Center Integrated Services Development Initiative[g1] Chase Brexton Health Services received an ARRA-Capital Improvement Program grant to support the following activities/projects:1) expand and renovate the existing pharmacy, as well as purchase additional equipment to support pharmacy op... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF MARYLAND $643,330 Trans-NIH Recovery Act Research Support Costameres are structures at the surface of striated muscle that align the sarcolemma regularly with nearby myofibrils and transmit contractile force laterally, through the membrane to the extracellular matrix. Costameres must therefore be linked to nearb
This spending item is part of a $758,231 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $641,500 Trans-NIH Recovery Act Research Support This proposal requested funds for an Ibis T6000 Biosensor System that incorporates broad-range PCR followed by electrospray ionization time-of-flight (ESI-TOF) mass spectrometric analysis to determine the precise base composition of the PCR amplicons. The National Institutes of Health 7/01/2010
UNIVERSITY OF MARYLAND $635,234 Trans-NIH Recovery Act Research Support The Human Microbiome Project (HMP) is an NIH Roadmap program that will produce unprecedented amounts of information about the microbial communities living on and within humans. The objective of our current work is to provide a Data Analysis and Coordinati
This spending item is part of a $1,147,846 allocation. See details
National Institutes of Health 9/10/2009
JOHNS HOPKINS UNIVERSITY, THE $635,046 Trans-NIH Recovery Act Research Support Our work under the parent grant addresses the functions of the recently discovered melanopsin light-signaling system. The overall goal is to understand the light-response properties and biophysics of the melanopsin-expressing retinal ganglion cells (the i National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $632,421 Trans-NIH Recovery Act Research Support WE are isolating and characterizing human mobile element polymorphisms, specifically L1s and Alus. These polymorphisms are called RIPs or retrotransposon insertion polymorphisms. WE plan to produce a microarray that is specific for the detection of these National Institutes of Health 8/10/2010
UNIVERSITY OF MARYLAND $628,633 Trans-NIH Recovery Act Research Support Hot flushes pose a significant public health concern world-wide. These perimenopausal symptoms are the primary reason that women seek medical care during the menopausal transition. Hot flushes often negatively impact the quality of life of women because t
This spending item is part of a $705,517 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $622,500 Trans-NIH Recovery Act Research Support Solid tumors are complex tissues containing both neoplastic tumor cells and non-neoplastic cell types (e.g., vascular endothelial cells (EC), fibroblasts and macrophages) and the interactions between these cells can regulate tumor progression. For example National Institutes of Health 5/07/2009
JOHNS HOPKINS UNIVERSITY, THE $600,000 Trans-NIH Recovery Act Research Support This proposal entitled 'Dynamic Regulation of shank3 and ASD' examines the molecular mechanisms that link human mutations of shank3 with Autism Spectrum Disorder (ASD). Mutations of the open reading frame of shank3 have been identified in multiple cases o National Institutes of Health 9/25/2009
AGING, MARYLAND DEPARTMENT OF $600,000 ARRA - Communities Putting Prevention to Work: Chronic Disease Self-Manage In collaboration with the ARRA-funded Communities Putting Prevention to Work (CPPW) program, this ARRA funding will support the deployment of evidence-based chronic disease self-management programs (CDSMP) that empower older p... Show more Administration on Aging 3/31/2010
JOHNS HOPKINS UNIVERSITY, THE $586,940 Trans-NIH Recovery Act Research Support DiffeProper transgene expression is essential to achieve therapeutic effect and ensure safety in many gene therapy strategies. Current regulation systems for controlling transgene expression typically require use of a special promoter and co-delivery of a
This spending item is part of a $1,621,296 allocation. See details
National Institutes of Health 6/03/2009
JOHNS HOPKINS UNIVERSITY, THE $580,088 Trans-NIH Recovery Act Research Support The grant entitled ?How does a4b1 integrin regulate cell migration? proposes to investigate a novel association between the cytoplasmic tail of a4 integrin and non-muscle myosin IIA (MIIA). Two aims are proposed to study this association: (1) characterize National Institutes of Health 8/10/2009
JOHNS HOPKINS UNIVERSITY, THE $572,797 Trans-NIH Recovery Act Research Support This application is to evaluate promising new therapies for patients with malignant disease in a clinically efficient, regulatory-compliant, and scientifically rigorous research environment. Phase I clinical studies of new anti-cancer therapies continue t National Institutes of Health 9/28/2009
BALTIMORE MEDICAL SYSTEM, INC. $572,742 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Increased Demand for Services: This Grant provides funding for the retention of 4.3 Healthcare providers and support staff that were scheduled for a reduction in force action due to lack of funds to support their salaries and be... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF MARYLAND $570,000 Trans-NIH Recovery Act Research Support Spermatogenesis is regulated by a cascade of regulatory events involving activation of a robust transcription program in spermatocytes. Understanding the mechanisms that control this program is critical for identification of generic defects that disrupt s National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $569,328 Trans-NIH Recovery Act Research Support OVERALL PURPOSE: TODAY is a collaborative group funded by the National Instituate of Diabetes and Digestive and Kidney Diseases (NIDDK) to conduct +B20t a clinical trial of therapies in children with type 2 diabetes (T2D). The TODAY study has enrolled 70
This spending item is part of a $1,102,576 allocation. See details
National Institutes of Health 4/12/2010
JOHNS HOPKINS UNIVERSITY, THE $558,471 Trans-NIH Recovery Act Research Support Understanding the neural mechanisms of tinnitus. The grant supports personnel and equipment needed to carry out an investigation into the neural activity in the brain that may underly tinnitus. Tinnitus is a phantom sound percept that occurs in many older National Institutes of Health 9/17/2009
UNIVERSITY OF MARYLAND $548,803 The Contractor shall provide services to the National Institute of Biomedical Imaging and Bioengineering (NIBIB) in the design, development, and launch of an Internet-based network for patient-controlled medical image sharing built upon the Integrating th
This spending item is part of a $4,697,377 allocation. See details
National Institutes of Health 9/30/2009
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $548,064 Trans-NIH Recovery Act Research Support This application is submitted by a group of investigators at 9 sites distributed throughout the U.S. where there are active developmental research programs involving substantial numbers of typically developing children, and neuroimaging investigators with
This spending item is part of a $8,950,690 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $546,484 Trans-NIH Recovery Act Research Support Head and Neck Squamous Cell Carcinoma (HNSCC) is a disease with significant morbidity and mortality, and without reliable indicators for prognosis, local recurrence, or presence of premalignant disease. This project is focused on validation of epigenetic, National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $533,053 Trans-NIH Recovery Act Research Support The purpose of this application is to enhance both the process and benefits of clinical andtranslational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying out scienti National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $528,962 Trans-NIH Recovery Act Research Support We have developed a plan for a NINDS research organization/consortium to develop, characterize and study iPS cell lines for Parkinson's disease (PD). The overall goal of this consortium of multiple- Pis (see leadership plan) is to organize the rapidly exp
This spending item is part of a $3,700,091 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF MARYLAND $525,000 Trans-NIH Recovery Act Research Support The research project focuses on the development of efficient chemoenzymatic methods for synthesizing N-glycopeptides and N-glycoproteins of biomedical significance. N-linked glycosylation is a major posttranslational modification of proteins in eukaryotes National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $523,967 Trans-NIH Recovery Act Research Support Cancer Genome Characterization Center at Johns Hopkins: In the past two decades, it has become clear that cancer arises not only as a consequence of genetic events, such as mutations, copy number alterations, and sequence rearrangements, but also as a res National Institutes of Health 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $521,658 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This project applies genomic and high-throughput genetic strategies to the global health emergency of tuberculosis. It creates new resources that will bridge clinic and laboratory, and quicken research for new, cheaper
This spending item is part of a $3,994,132 allocation. See details
National Institutes of Health 9/29/2010
JOHNS HOPKINS UNIVERSITY, THE $521,186 Trans-NIH Recovery Act Research Support Parkinson's disease (PD) is a neurodegenerative disorder characterized by death of substantia nigra (SN) dopamine neurons (DANs), dopamine deficiency within the striatum and a clinical movement disorder. Most PD is sporadic/idiopathic that may arise from
This spending item is part of a $3,907,801 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $517,939 Trans-NIH Recovery Act Research Support Specific aims of the supplement: Specific Aim 1: To enhance the activities of the CITAD clinical trial by increasing the tempo of participant recruitment by providing $10,000 for two years in direct costs to all study sites. This will result in an earlier
This spending item is part of a $581,127 allocation. See details
National Institutes of Health 9/04/2009
JOHNS HOPKINS UNIVERSITY, THE $510,450 Trans-NIH Recovery Act Research Support A mechanistic understanding of cancer rests heavily upon the mutated genes. Mutated genes include the dominant oncogenes and recessive suppressor genes that are mutated somatically to drive tumorigenesis. Pancreatic cancer has historically been an unusual National Institutes of Health 5/13/2009
JOHNS HOPKINS UNIVERSITY, THE $506,124 Trans-NIH Recovery Act Research Support Comparative phenotypic, functional, and molecular analysis of pluripotent stem cells arguably the most significant challenge in stem cell biology today is determining whether human induced pluripotent stem cells (hiPSC) are truly equivalent to human embry
This spending item is part of a $3,432,177 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $503,200 Trans-NIH Recovery Act Research Support Statistical Methods for Population Health Research on Chemical Mixtures. PI has moved to Harvard; grant to be transferred to Harvard. National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $500,000 Trans-NIH Recovery Act Research Support This award will provide partial funding for renovation of Bldg 12 at the JHU farm to provide space for the expansion of an NIH supported colony of pigtailed macaques. These animals are used in NIH funded programs at Johns Hopkins and other institutions in National Institutes of Health 7/15/2009
JOHNS HOPKINS UNIVERSITY, THE $498,683 Trans-NIH Recovery Act Research Support This project focuses on the production to MRM assays for the quantification of one or more protein in clinical sample sets. A group of very experienced investigators with targeted studies to address key clinical questions will use the dual liquid chromato National Institutes of Health 4/08/2010
JOHNS HOPKINS UNIVERSITY, THE $498,474 Trans-NIH Recovery Act Research Support This award will be used to obtain a new multiphoton microscope to study the physiology and pathophysiology of intestinal tissue, a pancreas and a heart using whole animal models. The instument will be used mainly by four NIH funded investigators, the memb National Institutes of Health 5/06/2010
UNIVERSITY OF MARYLAND $497,557 Trans-NIH Recovery Act Research Support The human body encounters most pathogens through mucosal sites. Two main portals are the lung and gut, where pathogens are encountered through the aerodigestive tract mucosa and oral ingestion. While both of these organs harbor resident immune cells for p National Institutes of Health 9/27/2010
UNIVERSITY OF MARYLAND $496,600 Trans-NIH Recovery Act Research Support The goal of the proposed project is to develop a community driven, open source Disease Ontology (DO) that can be used to link disparate datasets through disease concepts. We will provide a computable structure of inheritable, environmental and infectious
This spending item is part of a $991,237 allocation. See details
National Institutes of Health 7/14/2009
JOHNS HOPKINS UNIVERSITY, THE $495,330 Trans-NIH Recovery Act Research Support This award is for the purchase of a high accuracy quadrupole time-of-flight (QTOF) mass spectrometer with high resolution, high sensitivity and fast duty cycle to assist a productive group of investigators at Johns Hopkins University School of Medicine an National Institutes of Health 5/27/2010
JOHNS HOPKINS UNIVERSITY, THE $495,155 Trans-NIH Recovery Act Research Support This award responds to RFA-CA-08-504 which is intended to continue support for Phase 1 and 2 treatment studies in adults with primary central nervous system cancers and to continue the activities that were funded initially under RFA CA-04-001. This single
This spending item is part of a $742,737 allocation. See details
National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $492,599 Trans-NIH Recovery Act Research Support The Multicenter AIDS Cohort Study (MACS), a comprehensive cohort study ongoing since 1984, has contributed to the understanding of the natural history of HIV infection and the impact of highly active antiretroviral therapies (HAART). Combining genetic, vi National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $492,000 Trans-NIH Recovery Act Research Support Description remains unchanged. Diabetes is a leading cause of cardiovascular disease, end-stage renal disease, blindness and debilitating neuropathies. Hyperglycemia is the root cause of these maladies, but the mechanisms of glucose toxicity are unclear. National Institutes of Health 4/05/2010
UNIVERSITY OF MARYLAND $491,628 Trans-NIH Recovery Act Research Support Following the anthrax bioterror attacks in the US in 2001, awareness of the potentially devastating effects of attack with a bioweapon led to recognition of the need to take action and prepare against possible future nefarious events. F. tularensis was pl
This spending item is part of a $1,137,892 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $485,968 Trans-NIH Recovery Act Research Support This award responds to RFA-CA-08-504 which is intended to continue support for Phase 1 and 2 treatment studies in adults with primary central nervous system cancers and to continue the activities that were funded initially under RFA CA-04-001. This single
This spending item is part of a $885,989 allocation. See details
National Institutes of Health 7/17/2009
TKC GLOBAL SOLUTIONS LLC $474,769 Exercised second option year for software licenes and maintenance - partially funded by ARRA. Health Care Financing Admin. (was Medicare and Medicaid Serv.) 12/30/2011
JOHNS HOPKINS UNIVERSITY, THE $474,383 Trans-NIH Recovery Act Research Support Defining of Neurodevelopmental Pathways Regulated by Neuregulin- DISC1 Interactions Determining if neuregulin 1 (NRG1) signaling modulated DISC1 expression in the developing brain is a goal of this project. Towards this goal, we found that NRG signaling
This spending item is part of a $932,912 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $474,030 Trans-NIH Recovery Act Research Support We are requesting funds to purchase an Alba fluorescence lifetime imaging microscopy (FLIM) that will be housed in the University of Maryland-Baltimore Center for Fluorescence Spectroscopy (CFS), a campus-wide resource. The FLIM is a highly advanced spect National Institutes of Health 4/22/2010
JOHNS HOPKINS UNIVERSITY, THE $469,986 Trans-NIH Recovery Act Research Support This S10 Shared Instrumentation Grant application seeks funding in support of confocal live imaging resources for the Johns Hopkin University's Center for Functional Investigation in Zebrafish, also known as FinZ Center. FinZ Center was established i National Institutes of Health 7/08/2010
CARPET FOR PENNIES INC $465,982 Construction Manager as Constructor at Risk services to renovation Building 10, F Wing in two phases: Phase A of the F Wing Renovation: Pre construction, construction, activation/occupancy and closeout; to convert 64,000 gsf of former patient care units o
This spending item is part of a $131,640,100 allocation. See details
National Institutes of Health 7/30/2010
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $465,558 Trans-NIH Recovery Act Research Support This is a proposal to extend our image analysis technologies developed in the parent grant to translational researches. In the parent grant, we developed cutting-edge atlas-based automated brain segmentation and user-interface software for dissemination.
This spending item is part of a $894,666 allocation. See details
National Institutes of Health 8/28/2009
UNIVERSITY OF MARYLAND $465,554 Trans-NIH Recovery Act Research Support This is a competing renewal application. The overall thrust of the project is to develop novel fluorescent sensing and imaging technology for understanding the biology of zinc, with a view to developing novel and improved diagnostics and therapies for hum
This spending item is part of a $750,886 allocation. See details
National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support A. phagocytophilum and NF-kB signaling. This project will investigate how Anaplasma phagocytophilum influences proinflammatory cellular mechanisms by impacting NF-kB activation. The specific pre-nuclear mechanisms targeted in the generation of active NF-k National Institutes of Health 8/01/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support The aim of the study is to examine racial differences in sexual partner characteristics and determine whether neighborhood drug markets influence sex partner characteristics and sexually transmitted infections (STI) status of non-illicit drug using Africa National Institutes of Health 6/01/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support This award is supporting a single project concerning drug abuse, risky decision-making and HIV/AIDS. In addition to the sharing of intravenous injection equipment, another major contribution of drug dependence to HIV risk involves the association of cocai National Institutes of Health 5/21/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support The HIV-1 virion infectivity factor (Vif) is an essential regulatory protein required for HIV-1 replication in natural target cells such as CD4+ T-cells and macrophages. Recent studies from our group and others have demonstrated that Vif is a critical vir National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support The major functions of the gut epithelial compartment in a complex organism is to provide a protective barrier from pathogenic organisms that gain entry through the GI tract as well as facilitate the absorption and distribution of needed nutrients. These National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support We received 2 years of funding from ARRA funds, with the first year allocation of $ 205,000, for an application to the NIMH originally submitted as an R21, entitled 'Neurons from pluripotent stem cells derived from schizophrenia patient fibroblasts'.-? Th National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $451,000 Trans-NIH Recovery Act Research Support Mechanisms of schizophrenia-like phenotypes in BACE 1 knockout mice. Schizophrenia is known to have a genetic basis but genome-wide association studies have revealed highly inconsistent findings. One gene that has been repeatedly linked to schizophrenia i National Institutes of Health 5/05/2009
JOHNS HOPKINS UNIVERSITY, THE $449,458 Trans-NIH Recovery Act Research Support Age-related macular degeneration (AMD), the leading cause of irreversible blindness among elderly people in the developed countries, is a complex disease caused by multiple genetic and environmental factors, and currently 1.75 million people are suffering National Institutes of Health 8/19/2009
JOHNS HOPKINS UNIVERSITY, THE $446,782 Trans-NIH Recovery Act Research Support The project is aimed at developing new image analysis techniques to characterize brain atrophy in the R6/2 mouse line, a mouse model of Huntington's disease (HD). Atrophy of specific brain structures is known to be an important marker of HD and other National Institutes of Health 7/15/2009
JOHNS HOPKINS UNIVERSITY, THE $444,600 Trans-NIH Recovery Act Research Support Gender factors influencing susceptibility to influenza: The overarching aim of this proposal is to develop an animal model that enables us to test the hypothesis that gender differences in susceptibility to influenza virus infection reflect differential r National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $443,832 Trans-NIH Recovery Act Research Support The major goal of this one-year project is to provide a firm foundation for the mechanistic analysis of pathology development in Wilson?s disease (WD). WD is a severe human disorder of copper homeostasis. The gene mutated in WD encodes a copper-transporti
This spending item is part of a $505,233 allocation. See details
National Institutes of Health 8/23/2010
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $442,750 Trans-NIH Recovery Act Research Support Relationship of MRI to ASIA Impairment Scale in Chronic Spinal Cord Injury. The objective of this investigation is two-fold: 1) to add to the classification value of the American Spinal Injury Association (ASIA) Impairment Scale by establishing imaging c National Institutes of Health 4/30/2009
JOHNS HOPKINS UNIVERSITY, THE $441,065 Trans-NIH Recovery Act Research Support This supplemental award provides support to Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Supplements including: 1) High Risk Acute Lymphoblastic Leukemia (HR-ALL) - Our results establish that we can use comprehensive genom
This spending item is part of a $4,023,579 allocation. See details
National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $440,877 Trans-NIH Recovery Act Research Support This award funded by the National Institute of Neurological Disorders and Stroke is entitled, ?Common-Path OCT for Real Time Imaging in Minimally Invasive Neurosurgery.? The main objective of the award is to develop and test ?laser-guided? smart neurosurg National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $437,021 Trans-NIH Recovery Act Research Support The central element in allergic diseases such as asthma, rhinitis and eczema, is the presence of IgE antibody. While there is general acceptance of the central role for IgE in these diseases, there remains only a poor understanding of the quantitative req National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $432,440 Trans-NIH Recovery Act Research Support This is a two year award to analyze the methylcitrate cycle in Candida glabrata, an important human pathogen. This cycle is a fungal specific cycle important in detoxification of propionyl-CoA by C. glabrata. Propionyl-CoA is a byproduct of fatty acid ?-o National Institutes of Health 8/11/2009
JOHNS HOPKINS UNIVERSITY, THE $431,855 Trans-NIH Recovery Act Research Support IMAGING VARENICLINE EFFECTS ON NICOTINE & DOPAMINE: GENE MODULATION Nicotine dependence (ND) is a complex behavior governed by genetic and environmental determinants. In fact specific variations in the genes that influence nicotinic receptors have been as National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $429,108 Trans-NIH Recovery Act Research Support This is a proposal to extend our image analysis technologies developed in the parent grant to translational researches. In the parent grant, we developed cutting-edge atlas-based automated brain segmentation and user-interface software for dissemination.
This spending item is part of a $894,666 allocation. See details
National Institutes of Health 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $428,606 Trans-NIH Recovery Act Research Support Title: UPLC with tandem MS for sensitive quantitative analysis of small molecules The ability to quantify drugs and their metabolites in cells, plasma, and tissues with high sensitivity and selectivity is an essential need of research projects that aim to National Institutes of Health 4/22/2010
MARYLAND MEDICAL RESEARCH INSTITUTE, INC. $423,600 Trans-NIH Recovery Act Research Support Silent Cerebral Infarct Multi-Center Clinical Trial - SCC National Institutes of Health 8/18/2009
JOHNS HOPKINS UNIVERSITY, THE $416,674 Trans-NIH Recovery Act Research Support These investigations will further define potential roles for new visual function tests and ocular imaging measures as potential outcomes for MS clinical trials, and will apply paradigms from MS vision research to acute ON as a more specific model for asse
This spending item is part of a $1,296,171 allocation. See details
National Institutes of Health 6/03/2009
UNIVERSITY OF MARYLAND $412,500 Trans-NIH Recovery Act Research Support One-fifth of the genome codes for secretory proteins; a small subset of these proteins represent peptide hormone signaling molecules. This proposal addresses the identification of novel secretory molecules involved in the control of metabolic function. Si National Institutes of Health 5/26/2009
UNIVERSITY OF MARYLAND $412,500 Trans-NIH Recovery Act Research Support The combined lifetime population incidence of mood disorders, including bipolar disorder and unipolar depression, is over 15%. Many of these individuals do not receive optimized pharmacological treatment, which is influenced by the fact that the ability t National Institutes of Health 5/07/2009
UNIVERSITY OF MARYLAND $412,500 Trans-NIH Recovery Act Research Support Allergic asthma is characterized by exaggerated Th2 inflammation resulting from interaction between DC and T cells. Molecules acting in this interaction, regulating cell activation and differentiation are desirable therapeutic targets. This proposal aims National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $410,000 Trans-NIH Recovery Act Research Support Masses of the pituitary gland (sellar masses) are common, representing approximately 15% of all intracranial masses. About half of the sellar masses are caused by a hormone-secreting adenoma and more easily diagnosed because of classical signs and symptom National Institutes of Health 5/11/2009
UNIVERSITY OF MARYLAND $410,000 Trans-NIH Recovery Act Research Support The parent award describes a series of experiments based on the hypothesis that more effective control of pathogenic costimulation pathway activation will prevent alloantibody elaboration and cardiac allograft vasculopathy (CAV) following heart transplant National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $410,000 Trans-NIH Recovery Act Research Support Malaria is responsible for more mortality than any parasitic disease. Malaria parasite species that infect humans, must first take up residence in liver cells before invading red blood cells which instigates the pathology associated with malaria. We are s National Institutes of Health 8/02/2010
JOHNS HOPKINS UNIVERSITY, THE $410,000 Trans-NIH Recovery Act Research Support The major goals of this project are to determine the signal transduction pathways utilized by human herpesvirus 8 (HHV-8)-encoded chemokine receptor (vGPCR) to promote survival of and virus productive replication in HHV-8 infected cells. The originally pr National Institutes of Health 7/26/2010
JOHNS HOPKINS UNIVERSITY, THE $404,880 Trans-NIH Recovery Act Research Support Malaria parasites, worldwide are responsible for 300-500 million new infections and 1-2 million deaths each year. An effective vaccine, however, remains elusive, partly due to antigenic diversity and the immune evasion strategies of the parasite. Recombin National Institutes of Health 6/04/2009
UNIVERSITY OF MARYLAND $399,129 Trans-NIH Recovery Act Research Support This effort requires the development of new therapies that target the provirus residing within infected cells in a status of non-productive infection. Advances toward that goal will require a quantum leap in our knowledge and understanding of the biology
This spending item is part of a $421,129 allocation. See details
National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $397,762 ARRA - Immunization The Maryland Emerging Infections Program (EIP) will use these funds to support the ?13-valent Pneumococcal Conjugate Vaccine Effectiveness Study (PCV13)? and the on-going ?Quadrivalent Meningococcal Conjugate Vaccine Effectiveness Study (MCV4)?. The PCV1
This spending item is part of a $449,422 allocation. See details
Centers for Disease Control and Prevention 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $396,880 Trans-NIH Recovery Act Research Support With completion of the genome sequence and the estimated 20-25,000 genes comprising its entirety, it has become clear to investigators that the complexity of humans cannot be fully explained by so few genes. Alternative splicing of mRNA provides an intric National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $396,880 Trans-NIH Recovery Act Research Support Title: 'Manipulation of Kinase Activity by KSHV LANA' Kaposi's sarcoma associated herpesvirus (KSHV) is a herpesvirus that is associated with the blood vessel lesion Kaposi's sarcoma and the B cell malignancies primary effusion lymphoma and mult National Institutes of Health 5/21/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $394,129 ARRA - Preventing Healthcare-Associated Infections The Maryland Emerging Infections Program (EIP) will use these funds to support G?Evaluation of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Non-Hospital SettingsG? and G?Innovations in Surveillance through the National Health Safe... Show more Centers for Disease Control and Prevention 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $393,600 Trans-NIH Recovery Act Research Support Sjogren?s syndrome is a systemic autoimmune disease with significant associated morbidity. Defining pathways of therapeutic potential will enable the development of rational therapy for the treatment of Sjogren?s syndrome. The overall goal of this project National Institutes of Health 9/01/2009
JOHNS HOPKINS UNIVERSITY, THE $390,967 Trans-NIH Recovery Act Research Support We are conducting an economic evaluation of a depression intervention Beat the Blues (BTB). Beat the Blues is being tested in a randomized trial funded by NIMH (R01 MH079814). The intervention involves up to 10 sessions (combination of home and telephone
This spending item is part of a $455,083 allocation. See details
National Institutes of Health 6/20/2011
JOHNS HOPKINS UNIVERSITY, THE $387,803 Trans-NIH Recovery Act Research Support This submission is in response to NOT-OD-09-058, entitled 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.' Enzymatic targeting of a radiopharmaceutical for the treatment of EBV-associated tumors is a novel stra National Institutes of Health 9/17/2009
UNIVERSITY OF MARYLAND $385,740 Trans-NIH Recovery Act Research Support T cell responses against dominant tumor antigens (TA) can kill tumor cells but are less effective against poorly immunogenic (subdominant) TAs. Therefore, strategies are needed to induce potent and long-lasting T cell responses against dominant and subdom National Institutes of Health 9/17/2010
FRIENDS RESEARCH INSTITUTE, INC $384,953 To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders.
This spending item is part of a $16,872,951 allocation. See details
National Institutes of Health 7/13/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $383,953 The Partnership in Applied Comparative Effectiveness Science (PACES) is an initiative that seeks to advance the science for comparative effectiveness research by leveraging available clinical trial data held by the Food and Drug Administration (FDA). The
This spending item is part of a $4,662,128 allocation. See details
Food and Drug Administration 9/19/2010
JOHNS HOPKINS UNIVERSITY, THE $380,541 Trans-NIH Recovery Act Research Support Myostatin (MSTN) is a secreted protein that normally acts to suppress muscle growth. Mice genetically engineered to lack MSTN activity have dramatic increases in muscle mass as a result of a combination of muscle fiber hypertrophy and increased fiber numb National Institutes of Health 5/15/2009
MARYLAND FAMILY NETWORK, INC. $379,323 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $24,040,405 allocation. See details
Administration for Children and Families 4/09/2009
UNIVERSITY OF MARYLAND $375,000 Trans-NIH Recovery Act Research Support Cystic fibrosis (CF) is an inherited lung disease characterized by mucus hypersecretion, reduced mucociliary clearance of inhaled bacteria, particularly Pseudomonas aeruginosa (PA), and chronic airway inflammation. While the exact molecular mechanisms lea National Institutes of Health 7/22/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $370,000 The Agency for Healthcare Research and Quality (AHRQ) has awarded a contract to American Institutes for Research. The contract is entitled Community Forum. The contract was awarded in the amount of $9,999,742. The purpose of this contract is to establish
This spending item is part of a $9,999,742 allocation. See details
Agency for Healthcare Research and Quality 8/11/2010
UNIVERSITY OF MARYLAND $369,937 Trans-NIH Recovery Act Research Support Seven million people suffer bone fractures annually in the U.S. Musculoskeletal conditions cost $215 billion/year. These numbers are increasing dramatically as the population ages. This project will develop the first injectable, moderate load-bearing, mac
This spending item is part of a $416,624 allocation. See details
National Institutes of Health 9/23/2009
MARYLAND FAMILY NETWORK, INC. $366,431 ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF): Provide child care financial assistance to low-income working families and fund activities to improve the quality of child care.
This spending item is part of a $24,040,405 allocation. See details
Administration for Children and Families 4/09/2009
JOHNS HOPKINS UNIVERSITY, THE $365,476 Trans-NIH Recovery Act Research Support Aging is a prominent and independent risk factor for a wide spectrum of diseases including organ failure, cancer, dementia, hypertension, diabetes and arthritis. During the past 50 years, the number of Americans age 65 years or older has nearly tripled fr National Institutes of Health 5/05/2009
JOHNS HOPKINS UNIVERSITY, THE $363,919 Trans-NIH Recovery Act Research Support The title of this project is, Oxidative damage and cone cell death in RP. The project is an administrative supplement to EY05951. Published studies from the parent grant have demonstrated that in retinitis pigmentosa (RP), after rod photoreceptors die, co National Institutes of Health 8/04/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $362,038 Trans-NIH Recovery Act Research Support Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $361,241 Trans-NIH Recovery Act Research Support Patient Outcomes 6 and 12 Months After ALTA, OMEGA and EDEN ARDS Network Trials: (1) Acelerating the pace and achievement of the parent grant via maximizing recruitment and retention of study participants, and (2) adding value to the parent grant via new National Institutes of Health 7/16/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $357,404 ARRA - Prevention and Wellness--State Territories and Pacific Islands To address the alarming trend in cigar use by youth, CHP will focus on initiatives reducing access to and raising awareness of the dangers of cigar use. CHP will work with youth, young adult, and Statewide supporters, along with ... Show more
This spending item is part of a $863,360 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
JOHNS HOPKINS UNIVERSITY, THE $355,465 Trans-NIH Recovery Act Research Support The overarching goal of this Program is to understand the molecular mechanisms that regulate cell activation. Activation of lymphocytes through specific recognition of antigen poses narrowly balanced benefits and risks, and hence is subject to tight regul National Institutes of Health 9/16/2009
JOHNS HOPKINS UNIVERSITY, THE $355,000 Trans-NIH Recovery Act Research Support This research will start to identify and break down racial and ethnic communications barriers and will serve as a model that could be implemented at other cancer centers and hospitals nationwide to improve minority participation in clinical trials. While
This spending item is part of a $4,180,489 allocation. See details
National Institutes of Health 9/27/2009
JOHNS HOPKINS UNIVERSITY, THE $350,350 Trans-NIH Recovery Act Research Support HIV/AIDS, tuberculosis (TB), malaria and trypanosomiasis are infectious diseases of major importance to international health causing tremendous disease burdens on populations globally. HIV, the greatest cause of death internationally, is pandemic with fat National Institutes of Health 5/20/2010
UNIVERSITY OF MARYLAND $349,914 Trans-NIH Recovery Act Research Support Skin cancer is an important health problem and is a major cause of cancer worldwide. Skin cancer chemoprevention by diet-derived agents is an important area of study. In the present proposal we study the ability of green tea polyphenols to regulate epi National Institutes of Health 9/25/2009
TOTAL HEALTH CARE, INC. $349,817 ARRA Health Center Integrated Services Development Initiative[g1] ARRA Increase in Demand for Services Proposed Initiatives 1. Facilitates access to Primary Care, by offering a medical home for insured and uninsured, at Total Health Care, Inc. 2. Expand existing services to include walk in/same day ... Show more Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $348,766 Trans-NIH Recovery Act Research Support The central element in allergic diseases such as asthma, rhinitis and eczema, is the presence of IgE antibody. While there is general acceptance of the central role for IgE in these diseases, there remains only a poor understanding of the quantitative req National Institutes of Health 8/02/2010
JOHNS HOPKINS UNIVERSITY, THE $346,500 Trans-NIH Recovery Act Research Support We have completed this single center randomized trial to test the effectiveness of daily supplementation of omega-3 fatty acids (3.6 g DHA/EPA) over 3 months in 31 adults with diabetes and proteinuria, on urine protein excretion. National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $344,086 Trans-NIH Recovery Act Research Support This application responds to NHLBI Participation in Research and Research Infrastructure 'Grand Opportunities' (RC2) (RFA-OD-09-004) for Large-scale DNA Sequencing and Molecular Profiling of Well-Phenotyped NHLBI Cohorts. The major goal of this proposal
This spending item is part of a $5,155,213 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $342,468 Trans-NIH Recovery Act Research Support The long-term objective of this proposal is to understand the role of the RNA polymerase II C-terminal repeat domain (CTD) in transcription regulation during cell growth and quiescence. Understanding this regulatory process will be important in understand National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $342,342 Trans-NIH Recovery Act Research Support This award is an administrative supplement for the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Group, specifically, it provides supplemental funding for the HIV-1 Infection & Transmission Project.
This spending item is part of a $350,901 allocation. See details
National Institutes of Health 9/27/2010
JOHNS HOPKINS UNIVERSITY, THE $341,558 Trans-NIH Recovery Act Research Support This award will be used to study the intestinal pathology caused by shiga toxin producing strains of E. coli bacteria with overall goal to develop new approaches to treat shiga toxin-induced intestinal and systemic diseases. Intestinal pathology caused by
This spending item is part of a $410,002 allocation. See details
National Institutes of Health 9/17/2009
UNIVERSITY OF MARYLAND $340,001 Trans-NIH Recovery Act Research Support Antibodies directed at various targets (especially Gal al,3Gal) and complement are pivotal mediators of hyperacute rejection of the heart, lung, and other organs. However in pig-to-human and pig-to-non-human primate models, we have consistently found that National Institutes of Health 9/01/2009
UNIVERSITY OF MARYLAND $339,284 Trans-NIH Recovery Act Research Support Cancers of the large intestine cause more deaths in the United States than those arising in any other organ but the lung. Despite tremendous progress, the factors that initiate and promote the progression of neoplasia in the colon are incompletely underst
This spending item is part of a $349,844 allocation. See details
National Institutes of Health 5/21/2009
JOHNS HOPKINS UNIVERSITY, THE $336,250 Trans-NIH Recovery Act Research Support The purpose of this application is to enhance both the process and benefits of clinical andtranslational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying out scienti
This spending item is part of a $400,000 allocation. See details
National Institutes of Health 9/07/2009
JOHNS HOPKINS UNIVERSITY, THE $336,200 Trans-NIH Recovery Act Research Support Title: Ancillary Studies to the AD Neuroimaging Initiative (R21). This award is for ancillary studies to the Alzheimer ?s Disease Neuroimaging Initiative (ADNI), a multi-site, longitudinal, prospective, naturalistic study of normal cognitive aging, mild c National Institutes of Health 5/18/2009
UNIVERSITY OF MARYLAND $333,782 Trans-NIH Recovery Act Research Support Cesarean section (CS) is currently used at over twice the rate recommended by the World Health Organization (CDC, 2006); use of the procedure has almost doubled in the last two decades for reasons that are as yet poorly understood. Overutilization results
This spending item is part of a $425,314 allocation. See details
National Institutes of Health 9/15/2009
UNIVERSITY OF MARYLAND $332,174 Trans-NIH Recovery Act Research Support We hypothesize that addictive drugs alter cellular lipid pathways in brain and peripheral tissues, and that such alterations influence the transition to compulsive drug use. A corollary of this idea is that peripheral lipid alterations might be used as bi
This spending item is part of a $1,090,736 allocation. See details
National Institutes of Health 9/30/2009
HEALTH CARE FOR THE HOMELESS, INC. $331,157 ARRA Health Center Integrated Services Development Initiative[g1] ARRA Increased Demand for Services: This grant provided $331157.00 to assist Health Care for the Homeless in meeting the needs of a burgeoning number of people experiencing homelessness who require our agency's comprehensive services. ... Show more Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $329,776 Trans-NIH Recovery Act Research Support Major depressive disorder (MDD) is the leading cause of disability in the world (WHO). The severe, recurrent form often onsets during childhood or adolescence and becomes chronic. Heritability (35-70%) is similar to that of other common disorders for whic
This spending item is part of a $3,378,613 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $329,400 Trans-NIH Recovery Act Research Support The primary aim of this Administrative Supplement proposal is to provide funding for study coordinator salary support at CKiD participating sites. The ability to secure the dedicated time of coordinators well trained in carrying out the CKiD protocol is c National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $328,000 Trans-NIH Recovery Act Research Support The overall goals of the Parental NIH/NCI grant # 5P01CA077664-10 entitled? High Throughput Genetic Analysis of Bladder Cancer? proposal are to improve our understanding of the molecular genetic changes that drive bladder cancer progression as we develop National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $325,079 Trans-NIH Recovery Act Research Support Genetic disorders can often provide key insights into normal physiological processes. In this project, we are studying the premature aging disorder Hutchinson-Gilford Progeria Syndrome (HGPS). Gaining an understanding of HGPS is important in its own right National Institutes of Health 9/25/2009
UNIVERSITY OF MARYLAND $324,265 Trans-NIH Recovery Act Research Support Vaginitis/vaginosis is one of the most common conditions for women to seek medical care. Some 10 million office visits are attributed to vaginitis, which accounts for a health care cost of over $500 million each year. Over 90% of vaginitis can be attribut
This spending item is part of a $567,190 allocation. See details
National Institutes of Health 8/23/2010
JOHNS HOPKINS UNIVERSITY, THE $323,160 Trans-NIH Recovery Act Research Support Although the constancy of genetic information is central, genomes are surprisingly unstable. Transposable elements, i.e.discrete DNA segments that can move between many non-homologous positions, are widespread, having been found in virtually all organisms National Institutes of Health 9/18/2009
UNIVERSITY OF MARYLAND $319,461 Trans-NIH Recovery Act Research Support Staphylococcus aureus is a gram positive, ubiquitous bacterial species, with the predominant reservoir in nature being humans. The increased use of implanted medical devices such as intramedullary rods, screws, plates, and artificial joints has provided a National Institutes of Health 8/16/2010
UNIVERSITY OF MARYLAND $317,514 Trans-NIH Recovery Act Research Support .Abstract G?Metabolomics Network for Drug Response PhenotypeG? Response to Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure G?Grand OpportunitiesG? (RC2), RFAOD- 09-004-Linking Metabolomics to Pharmacogenomics Cardiova
This spending item is part of a $4,507,931 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $316,208 Trans-NIH Recovery Act Research Support The Women's Interagency HIV Study (WINS) is a large, comprehensive cohort study designed to investigate a spectrum of questions relating to the pathogenesis and natural history of HIV infection among women in the era of highly active antiretroviral t National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $313,912 Trans-NIH Recovery Act Research Support Cardiac hypertrophic remodeling underlies a large component of the morbidity and mortality of heart disease. It affects nearly 10% of the world?s population given the high prevalence of hypertension and hypertrophy that evolves with it. Cyclic guanosine-3 National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $311,600 Trans-NIH Recovery Act Research Support A brief description of these initial and subsequent observations resulting from the parent grant?s support is included in the project summary and has not substantially changed. Using RNA differential display following cytokine withdrawal from a human myel National Institutes of Health 8/28/2009
UNIVERSITY OF MARYLAND $311,250 Trans-NIH Recovery Act Research Support T cell responses against dominant tumor antigens (TA) can kill tumor cells but are less effective against poorly immunogenic (subdominant) TAs. Therefore, strategies are needed to induce potent and long-lasting T cell responses against dominant and subdom National Institutes of Health 9/17/2010
JOHNS HOPKINS UNIVERSITY, THE $310,124 Trans-NIH Recovery Act Research Support This proposal responds to the GO Program 'ARRA Medical Sequencing Discovery Projects' to establish next-generation technologies for medical resequencing in smaller academic laboratories compared to larger facilities like the Genomic Sequencing Centers. In
This spending item is part of a $2,766,567 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $309,561 Trans-NIH Recovery Act Research Support The overall aim of the parent grant (Role of the RNA-binding Protein HuR in Inflammation) and the supplemental funding is to understand the role of posttranscriptional gene regulation in the response of airway epithelium to inflammation, by focusing on th National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $309,176 Trans-NIH Recovery Act Research Support This project is in association with the parent grant to launch the Schizophrenia Research Center at Johns Hopkins, in response to PAR-07-434 Silvio O. Conte Center to develop collaborative research in neuroscience of mental disorders (P20). The overall go National Institutes of Health 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $307,287 We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr
This spending item is part of a $2,725,275 allocation. See details
National Institutes of Health 9/27/2010
JOHNS HOPKINS UNIVERSITY, THE $307,147 Trans-NIH Recovery Act Research Support EVE is a consortium comprised of all U.S. investigators who have conducted genome-wide association studies (GWAS) of asthma and whose main objective is to combine results of individual studies to increase the overall power to identify asthma-susceptibilit
This spending item is part of a $7,375,208 allocation. See details
National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $302,235 Trans-NIH Recovery Act Research Support Hopkins Center for Population Aging and Health: An emerging consensus calls for the development of new interdisciplinary research within public health that integrates divergent perspectives, frameworks and methods. The HCPAH will be an interdisciplinary r National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $301,352 Trans-NIH Recovery Act Research Support The goal of the parent Center for Childhood Asthma in the Urban Environment (CCAUE) grant (5P50ES015903) RFA is to increase understanding of the ways exposure to indoor and outdoor airborne particulate matter and allergens result in airway inflammation an National Institutes of Health 9/19/2009
UNIVERSITY OF MARYLAND $300,000 Trans-NIH Recovery Act Research Support The rapid rise in antibiotic resistance in the past two decades increases the need for alternative therapeutic strategies. A current approach to developing new antibiotics is to target non-essential functions that reduce virulence of infecting organisms b National Institutes of Health 5/21/2009
UNIVERSITY OF MARYLAND $300,000 Trans-NIH Recovery Act Research Support The rapid rise in antibiotic resistance in the past two decades increases the need for alternative therapeutic strategies. A current approach to developing new antibiotics is to target non-essential functions that reduce virulence of infecting organisms b National Institutes of Health 8/30/2010
UNIVERSITY OF MARYLAND $297,736 Trans-NIH Recovery Act Research Support The CNRU of Maryland will focus on the influence of nutrition and exercise on risk for age-related chronic diseases, including obesity, type 2 diabetes, hypertension, cardiovascular disease (CVD), sleep disordered breathing, and osteoporosis. With the obe National Institutes of Health 7/27/2009
JOHNS HOPKINS UNIVERSITY, THE $296,669 Recovery Act Comparative Effectiveness Research - AHRQ This R13 Large Conference Grant from the Agency for Healthcare Research and Quality (AHRQ) supports the United States Cochrane Center (USCC) in collaboration with the US-based consumer advocacy coalition, Consumers United for Evidence-based Healt... Show more Agency for Healthcare Research and Quality 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $295,200 Trans-NIH Recovery Act Research Support The goals of our research program are to determine which interventions are most effective at reducing the burden of mortality and morbidity among women and children in high-risk populations in developing countries. At our field site in southern Nepal, acu National Institutes of Health 8/13/2009
UNIVERSITY OF MARYLAND $294,709 ARRA ? Equipment to Enhance Training for Health Professionals The University of Maryland School of Nursing (UMSON) requests funds from the HRSA Equipment to Enhance Training for Health Professionals (EETHP). Our project, the Equipment for Patient Safety in Undergraduate Education, will directly suppo... Show more Health Resources and Services Administration 9/01/2010
JOHNS HOPKINS UNIVERSITY, THE $293,970 Trans-NIH Recovery Act Research Support Thromboembolic events, including stroke, are a major cause of morbidity and mortality in patients with heart failure. Even with sinus rhythm, severe heart failure confers an annual stroke risk of ~4%. While historically ascribed to blood stasis, dysfuncti National Institutes of Health 7/16/2009
University of Maryland Medical Center Corporation $293,575 To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders.
This spending item is part of a $10,496,230 allocation. See details
National Institutes of Health 7/13/2009
UNIVERSITY OF MARYLAND $293,202 Trans-NIH Recovery Act Research Support The phylum Apicomplexa is constituted exclusively by protozoan parasites, several of which pose a significant threat to public health. The apicomplexan Plasmodium falciparum is the etiological agent of Malaria and can cause high mortality and morbidity in National Institutes of Health 4/29/2010
BALTIMORE, CITY OF $287,590 ARRA Health Center Integrated Services Development Initiative[g1] This project will provide equipment and connectivity which will allow the funded health center staff access to the City's computer network to allow for e-mail and the implementation of an electronic health record system. Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS UNIVERSITY, THE $287,235 Trans-NIH Recovery Act Research Support NSAM Fourth Wave: Respondent tracing and in-person interviewing. In September 2009 we received an administrative supplement from Recovery Act funds ($287,235) to continue our in-person efforts to interview NSAM respondents. These funds supplemented an NIH National Institutes of Health 9/29/2009
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $286,902 Trans-NIH Recovery Act Research Support The Go grant award funded a 2-year research project investigating a new modality of therapy directed at memory impairment in the elderly. Aging is often associated with cognitive deficits, especially decline in memory functions that depend on the structur
This spending item is part of a $1,332,400 allocation. See details
National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $285,702 Trans-NIH Recovery Act Research Support Interaction of germline and somatic changes in PCa progression Abstract Recent successes in discovering germline variants associated with prostate cancer (PCa) risk is encouraging. However, whether these risk variants play role in PCa progression is uncle
This spending item is part of a $819,892 allocation. See details
National Institutes of Health 7/17/2009
BALTIMORE, CITY OF $284,578 ARRA - Immunization The goal for the use of these funds is to increase the number of children and adults vaccinated against vaccine-preventable diseases. Grant funds will be allocated in the following manner: School-Age Influenza Campaign: $1,500.000 LHD Special Projects:
This spending item is part of a $1,945,219 allocation. See details
Centers for Disease Control and Prevention 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $283,133 Trans-NIH Recovery Act Research Support This supplement to NIAMS grant R01AR041135 provided funds to identify genetic modifiers of Loeys-Dietz syndrome using mouse models. This funding will support personnel, reagent and service costs. National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $279,999 Trans-NIH Recovery Act Research Support The Experience Corps-? is a community-based model for health promotion for older adults embedded within a social engagement program. Our study population is predominantly older, African-American women in Baltimore City. The program incorporates health pro National Institutes of Health 9/21/2009
PEOPLE'S COMMUNITY HEALTH CENTER, INC., THE $279,912 ARRA Health Center Integrated Services Development Initiative[g1] People's Community Health Center, Inc.'s Increased Demand for Services Project was focused on providing jobs for those most impacted by the economic downturn. Through the employment of intake workers, medical assistance, substance abu... Show more Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $279,110 Trans-NIH Recovery Act Research Support Abstract Bilateral loss of vestibular function (inner ear balance sensation) due to ototoxic hair cell injury is disabling, with patients suffering disequilibrium and inability to maintain stable vision during head movements typical of daily life. While m National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $278,653 Trans-NIH Recovery Act Research Support ?Molecular genetics of thermotaxis and insect response to insect repellents? The focus of the parent grant is to dissect the mechanisms underlying thermotaxis and the aversion to insect repellents in the fruit fly. The specific goals are to identify and c National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $276,777 Trans-NIH Recovery Act Research Support The purpose of this supplement is to accelerate enrollment of the EARLI cohort as well as expand enrollment diversity and enhance retention. Each of the four study sites will hire one additional dedicated outreach/recruitment specialist to help increase
This spending item is part of a $1,111,301 allocation. See details
National Institutes of Health 9/20/2009
UNIVERSITY OF MARYLAND $276,723 Trans-NIH Recovery Act Research Support We are submitting a One Year Competing Revision of R01 AG 16613 according to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This competing revision supports a signific National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $276,723 Trans-NIH Recovery Act Research Support We are submitting a One Year Competing Revision of R01 AG 16613 according to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This competing revision supports a signific National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $273,614 Trans-NIH Recovery Act Research Support Graft-versus-host disease (GVHD) is caused by orchestrated host-reactive donor T cell responses and remains a major complication of allogeneic bone marrow transplantation (BMT) or hematopoietic stem cell transplantation. Although GVHD can be attenuated by National Institutes of Health 8/01/2009
JOHNS HOPKINS UNIVERSITY, THE $272,969 Trans-NIH Recovery Act Research Support In this Request for Leica High-pressure Freezer and Automated Freeze-substitution System, we aim to improve the fidelity of electron microscopy for basic biomedical research. Although electron microscopy provides the most detailed images of cellular and t National Institutes of Health 4/01/2010
UNIVERSITY OF MARYLAND $269,102 Trans-NIH Recovery Act Research Support We submit this proposal in response to RFA-OD-09-004 'Grand Opportunities (GO)' and NHLBI requests for applications to one of its 9 selected high-priority topics, 'Characterizing Differentiated Heart, Lung, and Blood Cells Derived by Reprogramming Human E
This spending item is part of a $1,251,292 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $269,045 Trans-NIH Recovery Act Research Support This supplement provides funding for 1 FTE postdoctoral fellow and lab funds for 2 years to expand the scope of a funded RO1. Since funding began this summer, Dr. Polina Sysa has joined the project and is now concentrating on increasing the mice colony an National Institutes of Health 7/16/2009
City of Baltimore $266,474 Aging Congregate Nutrition Services for States ARRA provided funding for congregate nutrition services. Established in 1972 under the Older American Act, the program provides meals for older americans in congregrate facilities such as seniors centers, adult day care centers,and faith based settings.... Show more
This spending item is part of a $1,110,512 allocation. See details
Administration on Aging 3/18/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $265,938 Trans-NIH Recovery Act Research Support Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $264,798 Trans-NIH Recovery Act Research Support Proposed is an ancillary study to the Transfusion Therapy Trial for Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) to examine the impact of the hemoglobin interventions on delirium in a sub-sample of 200 sub National Institutes of Health 8/01/2009
JOHNS HOPKINS UNIVERSITY, THE $263,920 Trans-NIH Recovery Act Research Support The main body of our research focuses on how lumican a protein present in connective tissues such as the cornea regulates innate immune response and immune privilege of the cornea. Innate immune and proinflammatory responses are necessary to protect the c National Institutes of Health 8/04/2009
PROFECTUS BIOSCIENCES, INC. $263,658 Trans-NIH Recovery Act Research Support There is increasing evidence that antibodies targeting the CD4 induced (CD4i) epitopes on the HIV envelope spike can facilitate control of viremia and quite possibly protection from transmission after exposure (reviewed in (1, 2)). We have developed a gp1
This spending item is part of a $936,985 allocation. See details
National Institutes of Health 9/29/2009
CENTER FOR PROMOTION OF CHILD DEVELOPMENT THROUGH PRIMARY CARE, THE $262,318 Trans-NIH Recovery Act Research Support The study's purpose is a cost-effectiveness study taking advantage of data from a large cohort derived from universal school screening for symptoms of ADHD collected by a web-based decision support system. Said system, called CHADIS, collects data from pa
This spending item is part of a $998,780 allocation. See details
National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $261,084 Trans-NIH Recovery Act Research Support Goals: The JHU Department of Biostatistics proposes a joint MHS-PhD built upon the existing Bioinformatics MHS and Biostatistics PhD programs. The program's goal is to produce graduates that will be full scientific partners on interdisciplinary biome National Institutes of Health 8/03/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $259,068 The Agency for Healthcare Research and Quality (AHRQ) has awarded a contract to American Institutes for Research. The contract is entitled Community Forum. The contract was awarded in the amount of $9,999,742. The purpose of this contract is to establish
This spending item is part of a $9,999,742 allocation. See details
Agency for Healthcare Research and Quality 8/11/2010
JOHNS HOPKINS UNIVERSITY, THE $254,474 Trans-NIH Recovery Act Research Support The Role of Endogenous Cardiac Glycosides in Outcomes among African Americans with Hypertensive Kidney Disease. Chronic kidney disease (CKD) affects an estimated 19 million adults in the US and is associated with a higher risk of cardiovascular disease (C
This spending item is part of a $325,504 allocation. See details
National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $253,186 Trans-NIH Recovery Act Research Support The results on coronary endothelial function on the parent RO1 are very promising. Different degrees of coronary atherosclerosis can be identified non-invasively using MRI. However, the related quantitative analysis of coronary artery endothelial function National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $252,944 ARRA ? Equipment to Enhance Training for Health Professionals The Equipment to Enhance Training of Health Professional, HRSA, ARRA Award Number: D76HP20550, Grant Number: 10895 project overall goal is to secure additional equipment that will be used to increase nursing education opportunities for ind... Show more Health Resources and Services Administration 8/31/2010
JOHNS HOPKINS UNIVERSITY, THE $252,791 Trans-NIH Recovery Act Research Support Cardiovascular disease is the number one killer in the US. The incidence and severity of inflammatory heart disease (myocarditis) is higher among men. Proinflammatory cytokines are critical for the development of myocarditis. Recent evidence suggests a li National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $251,266 Trans-NIH Recovery Act Research Support The focus of our U54 Center is on the hormonal and paracrine regulation of spermatogenesis in humans and rodents. There are three interrelated projects. Project I (Barry Zirkin and Jonathan Jarow) is addressing the biological mechanisms that explain why o National Institutes of Health 9/28/2009
CHASE BREXTON HEALTH SERVICES, INC $249,944 ARRA Health Center Integrated Services Development Initiative[g1] This Increased Demand for Services program funded through the American Recovery & Reinvestment Act award, provides comprehensive community health including case management to people who are uninsured or at risk of losing their insuranc... Show more Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $249,890 Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (05) Comparative Effectiveness Research (CER) and the specific Challenge Topic (05-MH-102) Cost Effectiveness of Mental Health Interventions. This study will conduct comparative cost-effectiveness analy
This spending item is part of a $560,391 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $249,556 Trans-NIH Recovery Act Research Support In all organisms, RNA molecules are needed to translate genes into protein, and to turn specific genes on and off. The malfunction of controlling RNAs has been linked to diseases such as muscular dystrophy, Fragile X mental retardation, and certain tumors National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $248,880 Trans-NIH Recovery Act Research Support Disruption of vestibular signals from one labyrinth results in asymmetries in the angular vestibuloocular reflex (VOR) evoked by high-frequency, high-acceleration head movements. Studies during the previous funding period have elucidated linear and nonlin National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $248,850 Johns Hopkins has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of lung adeno and squamous cell carcinoma tissue (119 cases). These cases are all prim National Institutes of Health 5/20/2010
JOHNS HOPKINS UNIVERSITY, THE $247,491 Trans-NIH Recovery Act Research Support Effect of cytokines in chronic rhinosinsusitis on olfactory neuron function: The purpose of the parent grant is to study the mechanism of olfactory loss in patients with chronic rhinosinusitis (CRS). The loss of the sense of smell is a common symptom of C National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $245,207 Trans-NIH Recovery Act Research Support In the twenty-first century, cervical cancer prevention programs represent the expenditure of significant public health dollars. In anticipation of changes in cervical cancer prevention strategies such as first- and second- generation human papillomavirus
This spending item is part of a $2,421,152 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $243,653 Trans-NIH Recovery Act Research Support Project 1: The development of new ideas and approaches to understanding the mechanisms of natural HIV-1 resistance. In collaboration with the University of Washington, we hypothesize that HIV-1 infection in high risk seronegatives (HRSN) is below the dete
This spending item is part of a $2,221,266 allocation. See details
National Institutes of Health 5/03/2010
PINNACLE COMMUNICATIONS RESOURCE COMPANY A LIMITED LIABILITY COMPANY $240,000 ARRA - Prevention and Wellness--State Territories and Pacific Islands With the ARRA funding, the Center for Health Promotion, Education and Tobacco Use Prevention (CHP) will be able to expand and promote the Maryland Tobacco Quitline program through the following activities: 1) Create a position... Show more
This spending item is part of a $750,534 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
JOHNS HOPKINS UNIVERSITY, THE $239,747 Trans-NIH Recovery Act Research Support The purpose of the parent grant is to determine the role of the TraI protein in the transfer of the F plasmid between bacteria. In addition to chromosomes, bacteria can possess pieces of DNA called plasmids. Some plasmids, such as the F plasmid we study, National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $238,048 Trans-NIH Recovery Act Research Support Mycobacterium tuberculosis (MTB) and human immunodeficiency virus (HIV) are two pathogens that have developed a terrifyingly successful relationship. Tuberculosis accounts for up to a third of AIDS-related deaths worldwide, and nearly one quarter of death National Institutes of Health 4/12/2010
JOHNS HOPKINS UNIVERSITY, THE $237,941 Trans-NIH Recovery Act Research Support This administrative supplement will be used to hire a full-time postdoctoral fellow and purchase some equipment and reagents for miR21 and ischemia-reperfusion study. This research will need additional staff to take care of mice or increase hours of curre National Institutes of Health 7/16/2009
UNIVERSITY OF MARYLAND $235,816 Trans-NIH Recovery Act Research Support This supplement proposes to begin to place the chemical damage wrought by the major metabolite of the carcinogen NMOR in the context of biological processes that bear on the consequences of the damage.
This spending item is part of a $662,733 allocation. See details
National Institutes of Health 9/09/2009
PARK WEST HEALTH SYSTEMS INCORPORATED $235,000 ARRA Health Center Integrated Services Development Initiative[g1] To assist Community HEalth Centers with an expected increased demand for services based on the current economic environment. Health Resources and Services Administration 3/27/2009
PARK WEST HEALTH SYSTEMS INCORPORATED $234,000 ARRA Health Center Integrated Services Development Initiative[g1] To assist Community Health Centers with an expected increased demand for services based on the current economic environment. Health Resources and Services Administration 3/27/2009
PARK WEST HEALTH SYSTEMS INCORPORATED $234,000 ARRA Health Center Integrated Services Development Initiative[g1] The purpose of the award is to assist Community Health Centers with an expected increased in demand for services based on the current economic environment. Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $232,945 Trans-NIH Recovery Act Research Support Supplemental funding to our ongoing R01 grant (AI072265) is requested for the purpose of retaining personnel who would be essential to the proposed work. We are also requesting funds to pay for the development of a new knockout mouse and purchase supplies National Institutes of Health 7/12/2010
JOHNS HOPKINS UNIVERSITY, THE $232,888 Trans-NIH Recovery Act Research Support The long-term goal of this research is to develop methods for time resolved, low dose cardiac CT imaging. Specifically, we will develop algorithms that estimate the time-dependent motion vector field of the heart from the measured data and integrate it in National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $232,165 Trans-NIH Recovery Act Research Support Environmental Strategies for Violence and AOD Prevention: Administrative Supplement to Provide Summer Research Experiences for Educators, College Students & High School Students. The purpose of the supplement is to conduct an expanded environmental survey National Institutes of Health 7/13/2009
CENTER FOR PROMOTION OF CHILD DEVELOPMENT THROUGH PRIMARY CARE, THE $231,143 Trans-NIH Recovery Act Research Support The study's purpose is a cost-effectiveness study taking advantage of data from a large cohort derived from universal school screening for symptoms of ADHD collected by a web-based decision support system. Said system, called CHADIS, collects data from pa
This spending item is part of a $998,780 allocation. See details
National Institutes of Health 9/23/2009
UNIVERSITY OF MARYLAND $230,606 Trans-NIH Recovery Act Research Support Despite significant advances in the understanding of the caries process and in the interventions needed to prevent it, early childhood caries (ECC) remains one of the most prevalent diseases among children in the United States and the world. The main obje
This spending item is part of a $290,986 allocation. See details
National Institutes of Health 4/29/2009
JOHNS HOPKINS UNIVERSITY, THE $229,600 Trans-NIH Recovery Act Research Support Our work addresses the functions and mechanisms of long-range growth factor signaling in vivo and in vitro. The title of our work is: The control of synapse assembly by target-derived Nerve Growth Factor (NGF). The overall purpose of this project is to un National Institutes of Health 8/17/2009
UNIVERSITY OF MARYLAND $228,180 Trans-NIH Recovery Act Research Support The long-term goal of this research is to engineer peptide-based viscoelastic biomaterials (hydrogels) that can be used as encapsulated matrices for drug delivery and tissue repair applications. The focus of this proposal is on design principles, characte National Institutes of Health 8/10/2009
UNIVERSITY OF MARYLAND $225,202 Trans-NIH Recovery Act Research Support There is a documented need for palliative care training for practitioners of internal medicine and related subspecialties at the post-doctoral level. Our project's goal is to create palliative and end-of-life competency assessment tools to be used in dail National Institutes of Health 9/15/2009
UNIVERSITY OF MARYLAND $225,000 Trans-NIH Recovery Act Research Support Project Summary Antibodies are highly useful reagents in biotechnological and biomedical applications, yet recombinant antibodies have their limitations. These include the complex architecture of their antigen-binding sites, which complicates the generat National Institutes of Health 7/23/2009
UNIVERSITY OF MARYLAND $225,000 Trans-NIH Recovery Act Research Support Fundamental understanding of the molecular mechanism governing osteoblast differentiation is essential for developing novel therapeutics for osteoporosis and bone fracture. Transglutaminases TG2 and FXIIIa promote osteoblast differentiation in vitro, and National Institutes of Health 4/12/2010
UNIVERSITY OF MARYLAND $224,486 Trans-NIH Recovery Act Research Support The hepatitis C virus (HCV) is an important pathogen that has infected approximately 170 million people worldwide. In spite of extensive efforts, surprisingly little is known about the mechanism by which HCV initiates infection. The lack of vaccine or eff National Institutes of Health 7/22/2009
JOHNS HOPKINS UNIVERSITY, THE $222,415 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) affects an estimated 19 million adults in the US, and is associated with an elevated risk of cardiovascular disease (CVD) and mortality. Clinical practice guidelines define CKD on the basis of both albuminuria and decreased ki National Institutes of Health 9/30/2010
JOHNS HOPKINS UNIVERSITY, THE $222,054 Trans-NIH Recovery Act Research Support The purpose of this supplement application is to provide the opportunity for a Postdoctoral fellow, Dr. Shinya Onogi, to obtain training and mentored support in the area of Image-Guided Orthopaedic Interventions by interacting with and taking part in an i National Institutes of Health 8/31/2009
UNIVERSITY OF MARYLAND $221,941 Trans-NIH Recovery Act Research Support The gastrointestinal tract is unique because of its highly proliferative stem cell population and therefore, is second only to the hematopoeitic system in sensitivity to radiation-induced injury. One of the most deleterious effects of radiation injury is National Institutes of Health 7/22/2009
JOHNS HOPKINS UNIVERSITY, THE $221,717 Trans-NIH Recovery Act Research Support Parent Grant entitled: The Role of Hepatocyte Growth Factor Signaling in Alveolar Homeostasis. Administrative Supplement Project entitled: The Role of Hepatocyte Growth Factor Signaling in Reparative Response to Neonatal Hyperoxic Injury. National Institutes of Health 7/20/2009
JOHNS HOPKINS UNIVERSITY, THE $221,311 Trans-NIH Recovery Act Research Support Title: Supplemental request for research technician and funds for state of the art instrument. An administrative supplement to R01 grant (GM34933) was awarded to facilitate our studies. The purpose of the supplement is to accelerate several screens for sp National Institutes of Health 8/31/2009
FAMILY HEALTH CENTERS OF BALTIMORE $220,139 ARRA Health Center Integrated Services Development Initiative[g1] The FHCB IDS project will be responsive to the health care needs of patients, culturally competent and Joint Commission compliant. The project will be implemented at the large practices - downtown and Cherry Hill. Missed appointments... Show more Health Resources and Services Administration 3/27/2009
JOHNS HOPKINS UNIVERSITY, THE $218,986 Trans-NIH Recovery Act Research Support Cell migration is a major driving force in embryonic development, wound healing, and tumor metastasis. Therefore understanding the molecular mechanisms that control whether, when, and where cells move is significant for human health and disease. My labora National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $217,911 Trans-NIH Recovery Act Research Support The objectives of the parent grant EB 006521 are to use a combination of theory, nanofabrication and spectroscopy to develop defined nanostructures which result in enhanced and/or directional fluorescence from surface-bound fluorophores. These defined str National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $216,613 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) is a major global public health problem. Environmental and occupational exposure to lead and cadmium may increase CKD risk independently and in conjunction with established causes, such as diabetes and hypertension. We are inv National Institutes of Health 9/06/2009
JOHNS HOPKINS UNIVERSITY, THE $216,153 Trans-NIH Recovery Act Research Support The Duet is a cervical barrier device that, unlike a diaphragm, delivers gel on both its upper and lower surfaces to protect the vagina as well as the cervix. This application proposes 3 related projects: 1) BufferGel-Duet, a single-use product for protec National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $213,557 Trans-NIH Recovery Act Research Support This project would entail expanding the current 12-color panels we have in two ways: 1) to create new 12-color panels that in addition to 6-8 anchor markers that recognize the main populations also incorporate markers of activation, inhibition/exhaustion
This spending item is part of a $1,290,000 allocation. See details
National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $210,601 Trans-NIH Recovery Act Research Support Second Sight Medical Products, Inc. (SSMP) has been developing retinal prostheses for over 10 years. Currently, the company is sponsoring a feasibility clinical trial for its Argus II system-a 60 electrode retinal prosthesis to treat advanced retinitis p
This spending item is part of a $2,988,224 allocation. See details
National Institutes of Health 4/23/2010
JOHNS HOPKINS UNIVERSITY, THE $208,227 Trans-NIH Recovery Act Research Support The award will allow the purchase of equipment for continuation of AIMs 1-4 of the original R01AI063764 and hiring of personnel to support the research. We expect to learn of mechanisms that control MHC class II antigen processing and the contribution of National Institutes of Health 6/28/2010
JOHNS HOPKINS UNIVERSITY, THE $207,383 Trans-NIH Recovery Act Research Support The remarkable sensitivity and specificity of mammalian olfaction arises from the contributions at the molecular, cellular and tissue levels to establish a sensory organ. One of the most important components in this developmental process is the olfactory National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $205,253 Trans-NIH Recovery Act Research Support The overall goal of the Alzheimer's Disease Research Center (ADRC) at Johns Hopkins University (JHU) is to facilitate research in Alzheimer's disease (AD) and related disorders throughout the research community at JHU and associated institutions National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $205,192 Trans-NIH Recovery Act Research Support Title: Support for postdoctoral fellow Dr. Zongtian Tong. Award provides funds for salary and supplies to support a postdoctoral research fellow, Zongtian Tong. Dr. Tong's project will advance our understanding of the regulation of SREBP transcriptio National Institutes of Health 7/17/2009
BALTIMORE, COUNTY OF $204,258 ARRA - Immunization The goal for the use of these funds is to increase the number of children and adults vaccinated against vaccine-preventable diseases. Grant funds will be allocated in the following manner: School-Age Influenza Campaign: $1,500.000 LHD Special Projects:
This spending item is part of a $1,945,219 allocation. See details
Centers for Disease Control and Prevention 9/15/2009
MD ST DEPARTMENT OF HUMAN RESOURCES $203,504 Foster Care_Title IV-E FY 2012 FOSTER CARE Administration for Children and Families 10/12/2011
UNIVERSITY OF MARYLAND $203,406 Trans-NIH Recovery Act Research Support The treatment with cardiovascular medical devices enhances survival for many patients with otherwise hopeless medical conditions. Unfortunately, in many cases these devices cause dangerous pathological complications, in particular thrombosis and thromboem National Institutes of Health 8/01/2009
JOHNS HOPKINS UNIVERSITY, THE $202,950 Trans-NIH Recovery Act Research Support Herpesviruses encode a ubiquitin-specific cysteine protease that was only recently discovered and determined to be incorporated into infectious virus as an active enzyme. Although it is embedded within the amino end of a well-characterized virion tegument National Institutes of Health 7/19/2010
UNIVERSITY OF MARYLAND $200,002 Trans-NIH Recovery Act Research Support This grant proposal focuses our sustained laboratory and clinical research experience in animal and human stem cell biology and leukemia to extend exciting new investigations on normal tissue-specific and cancer stem cells. The investigators in this PPG l National Institutes of Health 9/07/2009
UNIVERSITY OF MARYLAND $200,000 Trans-NIH Recovery Act Research Support This is a student administrative supplement to provide support for an undergraduate to wok in the laboratory. This will provide the undergraduate student an opportunity to gain valuable research experience and training. The Bmi-1 Polycomb Group (PcG) ge National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $199,311 Trans-NIH Recovery Act Research Support This ARRA was a supplement to my NIH RO1 13899 grant entitled ?Formation of the Drosophila salivary gland? in which we use the Drosophila salivary gland as a simple model system for learning how organs are specified, how they form and how they become spec National Institutes of Health 9/22/2009
PROFECTUS BIOSCIENCES, INC. $199,245 Trans-NIH Recovery Act Research Support There is increasing evidence that antibodies targeting the CD4 induced (CD4i) epitopes on the HIV envelope spike can facilitate control of viremia and quite possibly protection from transmission after exposure (reviewed in (1, 2)). We have developed a gp1
This spending item is part of a $936,985 allocation. See details
National Institutes of Health 9/29/2009
MARYLAND FAMILY NETWORK, INC. $199,143 ARRA - Head Start Maryland Family Network, Inc. (MFN),as the grantee for Early Head Start (EHS) and as the intermeidiary for its 6 delegate agencies, received COLA and Quality Improvement funds. COLA funds increased salaries and supported benefits to each EHS staff positio Administration for Children and Families 5/29/2009
JOHNS HOPKINS UNIVERSITY, THE $197,045 Trans-NIH Recovery Act Research Support Diabetes Research and Training Center This application is in response to the National Institutes of Health Notice NOT-OD-09-056 (administrative supplement for Research Center Grants). The Baltimore DRTC requests supplemental funding of programs that will
This spending item is part of a $277,045 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $197,034 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-DK-105: Allocation of Scarce Transplanted Organs.This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-DK-105. Organ
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/18/2009
UNIVERSITY OF MARYLAND $194,830 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $194,420 Trans-NIH Recovery Act Research Support LINE-1, or L1, elements, are the most prolific and prominent mobile elements in mammalian genomes. In the human and mouse genomes, active L1s and their relics account for 17-20% of the genome mass. By providing activities necessary for mobility of Alu and National Institutes of Health 9/24/2010
JOHNS HOPKINS UNIVERSITY, THE $193,887 Trans-NIH Recovery Act Research Support Successful development of a functional eye requires not only cell-differentiation programs that specify various retina cell types, but also size-control mechanisms that determine the number of cells in the retina. The long-term scientific goal of my labor National Institutes of Health 9/23/2009
UNIVERSITY OF MARYLAND BALTIMORE COUNTY $192,900 Trans-NIH Recovery Act Research Support The Southeast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) is an NIH/NIAID-funded consortium of institutions across the southeast established in 2003. SERCEBG??s mission is to assist the nation in developing and deploying
This spending item is part of a $1,462,023 allocation. See details
National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $191,682 Trans-NIH Recovery Act Research Support Innate immune responses of sinonasal epithelial cells to influenza infection in chronic rhinosinusitis with polyps: The purpose of the parent grant is to study innate immune mechanisms that underlie chronic rhinosinusitis with polyps (CRSwNP), which is a National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $191,610 Trans-NIH Recovery Act Research Support This research project was originally submitted as an Instrumentation Grant in response to PAR-08-036. The National Center for Research Resources awarded this project under the American Recovery and Reinvestment Act of 2009 (ARRA). The instrument, a COPAS National Institutes of Health 4/28/2009
JOHNS HOPKINS UNIVERSITY, THE $189,000 Trans-NIH Recovery Act Research Support Molecular Genetic Analysis of Colorectal Cancer: Activation due to phospho-peptide binding To fully elucidate the activation mechanism of the oncogenic mutations of PI3K? we designed mutants at the interfaces of the SH2 domains (both nSH2 and cSH2) with t National Institutes of Health 9/04/2009
JOHNS HOPKINS UNIVERSITY, THE $186,714 Trans-NIH Recovery Act Research Support This grant is focused on identifying and understanding the regulation of sub-telomeric virulence genes in C. glabrata. There are three sub-aims: 1) Sub-telomeres consist of regions repeated between different telomeres. In the current public database the s National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $183,263 Trans-NIH Recovery Act Research Support The long-term objective of this project has been to understand as fully and as deeply as possible, the principles governing the action of the regulatory protein AraC of the L-arabinose operon in the bacterium Escherichia coli and to expand these to elucid National Institutes of Health 7/15/2009
UNIVERSITY OF MARYLAND $183,024 Trans-NIH Recovery Act Research Support The integrity of the genetic information encoded by DNA is essential to all organisms, yet the reactive bases of DNA are continuously subjected to chemical modification from endogenous and exogenous sources. To counteract this inevitable damage, the cellu National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $174,903 Trans-NIH Recovery Act Research Support A HETEROLOGOUS EXPRESSION SYSTEM FOR APICOMPLEXA GENES The overarching goal of this study is to develop and validate P. marinus as a heterologous system for producing recombinant proteins from Apicomplexa. For that purpose, we intent to design and constru National Institutes of Health 5/14/2009
JOHNS HOPKINS UNIVERSITY, THE $174,250 Trans-NIH Recovery Act Research Support Afferent Synaptic Transmission in the Mammalian Cochlea: Parent Grant: This proposal seeks to investigate mechanisms of synaptic transmission at the inner hair cell (IHC) afferent synapse in the mammalian cochlea. In the inner ear, sound signals are conve National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $174,199 Trans-NIH Recovery Act Research Support Supplemental funding to our ongoing R01 grant (AI075025) is requested for the purpose of retaining a postdoctoral fellow and hiring a new postdoctoral fellow who would be essential to the proposed work and would greatly advance the specific aims of the pa National Institutes of Health 7/12/2010
JOHNS HOPKINS UNIVERSITY, THE $173,609 Trans-NIH Recovery Act Research Support This project is intended to be the critical test of the role of growth factors in modifying neuropathic and inflammatory pain in the mouse. We now have available genetically engineered lines of knock-in mice in which a small molecule inhibitor can abruptl National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $172,458 ARRA - Public Health Traineeship Program This project provides additional funding for the existing Public Health Traineeship program. The funds are used to support degree seeking students who plan to work in the following public health shortage areas: biostatistics, epidemiology, environmental h Health Resources and Services Administration 9/03/2009
JOHNS HOPKINS UNIVERSITY, THE $171,372 Trans-NIH Recovery Act Research Support Transposons such as piggyBac, Mos and Hermes that have been introduced into the germ-line of the mosquito, Aedes aegypti, are rendered immobile within a single generation. The same immobility post-transformation has also been observed for the Minos transp
This spending item is part of a $600,696 allocation. See details
National Institutes of Health 7/19/2010
UNIVERSITY OF MARYLAND $169,656 Trans-NIH Recovery Act Research Support Escherichia coli O157:H7 is the most common infectious cause of bloody diarrhea, or hemorrhagic colitis (HC), in the U.S, and the incidence of non-O157:H7 Shiga toxin-producing E. coli (STEC) is about half that of O157:H7. Moreover, the hemolytic uremic s
This spending item is part of a $170,442 allocation. See details
National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support This project will use specimens and epidemiological data -?collected from a series of field gonorrhea intervention projects conductied in Baltimore.-? The project will develop a method for typing gonococcal isolates (organisms) which uses proteins found o National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support Culture and Identification of Rickettsia-like Organisms in Maryland: the specific aims of this project are to 1) use shell-vial culture techniques to culture/isolate known and unknown Rickettsia-like organisms from man-biting ticks of Maryland and 2) to i National Institutes of Health 5/29/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support Project title: CMV-encoded TNF receptor and virus dissemination The aims of the project are: to characterize NF-kB activiation with UL144 subtypes, to understand which region of UL144 is responsible to NF-kB activation, and to determine the effects of UL1 National Institutes of Health 6/18/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support Title: Mechanisms of VCP/p97 and Proteasomal Pathway in COPD Pathogenesis. Award Description: Cigarette smoking induces oxidative stress and unfolded protein response (UPR), and is the major risk factor for emphysema and COPD (chronic obstructive pulmonar National Institutes of Health 5/08/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support Title of the project is Targeting AP-1 proteins In COPD. Chronic obstructive pulmonary disease (COPD), which consists of emphysema and chronic bronchitis, is a major public health concern with no effective treatment. Various cellular processes that mainta National Institutes of Health 5/08/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support Our Administrative ARRA Supplement Aims remain: (1) Investigate novel, Rho GTPase-mediated, signaling events involving transmembrane semaphorin reverse signaling during Drosophila neural development, and; (2) Utilize genetically encoded fluorescent intrac National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $164,000 Trans-NIH Recovery Act Research Support The project funded by this ARRA supplement will advance our mechanistic understanding of the Biogenesis of Exosomes, small vesicles that are secreted by human cells, play important roles in immune signaling and development, and are implicated in cancers, National Institutes of Health 3/09/2010
JOHNS HOPKINS UNIVERSITY, THE $163,998 Trans-NIH Recovery Act Research Support IBD Gene Mapping By Clinical and Population Subsets. Inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis, is a complex genetic disorder. The distribution of disease genes varies by ethnic ancestry. Despite the large African Ameri National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $163,923 Trans-NIH Recovery Act Research Support There is an urgent need for cost-effective, non-invasive diagnostic techniques for the evaluation of breast lesions. The primary objective of this project is to develop a multiparametric MRI based tissue model to differentiate benign from malignant tissue National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $163,656 Trans-NIH Recovery Act Research Support Mechansisms of preferential reinveration Over 40,000 Americans suffer peripheral nerve injury each year. Of these, only 10% will regain normal function. Results of surgical treatment are compromised by the limited ability of peripheral nerve to support ax National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $162,530 Trans-NIH Recovery Act Research Support Information Processing & the Inferior Colliculus. This is a supplement to the grant with the title above. It is intended to accelerate the science (ACC) in that grant by supporting additional personnel and to purchase research equipment (EQ). National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $162,114 Trans-NIH Recovery Act Research Support 501HD038384-07, GENOMIC APPROACHES TO ANEUPLOIDY ? REQUEST FOR ADMINISTRATIVE SUPPLEMENT We seek an administrative supplement to directly extend experiments in Specific aims 1 and 2 to forward progress in this grant and in the community of Down syndrome r National Institutes of Health 7/07/2010
JOHNS HOPKINS UNIVERSITY, THE $161,615 Recovery Act Comparative Effectiveness Research - AHRQ The primary goal of the PATIENT study (Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies) is to increase both initial use and ongoing adherence to three classes of medications used to treat diabetes or cardiovascula... Show more
This spending item is part of a $6,466,949 allocation. See details
Agency for Healthcare Research and Quality 8/31/2010
JOHNS HOPKINS UNIVERSITY, THE $161,047 Trans-NIH Recovery Act Research Support A collaborative team involving investigators led by the Institute of Human Virology-University of Maryland (IHV) will identify 115 pregnant women with acute HIV infection. Our long-term goal is to advance the understanding of mother-to-child transmission
This spending item is part of a $292,795 allocation. See details
National Institutes of Health 6/02/2010
UNIVERSITY OF MARYLAND $160,137 Trans-NIH Recovery Act Research Support Anthrax toxin consists of three proteins secreted by Bacillus anthracis - protective antigen (PA), edema factor (EF) and lethal factor (LF). LF is a Zn2+-dependent metalloprotease that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) National Institutes of Health 9/07/2010
JOHNS HOPKINS UNIVERSITY, THE $159,819 Trans-NIH Recovery Act Research Support Bioinorganic Copper Coordination Chemistry - (i) obtain an advanced piece of equipment and to (ii) (ii) obtain salary support for a currently advanced postdoctoral associate who will carry out research using this equipment. Thus, the requests are integral National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $159,759 Trans-NIH Recovery Act Research Support Prostate cancer (PCa) is the most common cancer among men in the U.S. One important strategy to address this public health concern is to prevent the disease. Two large randomized clinical trials, The Prostate Cancer Prevention Trial (PCPT) and The Reducti
This spending item is part of a $3,978,770 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $159,567 Trans-NIH Recovery Act Research Support This award, 3R01GM075310-04S1, is a competitive Supplement to R01 GM075310 ``Group-Theoretic Methods in Protein Structure Determination'', in which the PI (G. Chirikjian) of the main grant is doing work to match theoretical models of protein loo National Institutes of Health 9/30/2009
COPPIN STATE UNIVERSITY $159,149 ARRA - Scholarships for Disadvantaged Students Scholarships awarded to minority students attending an HBCU Health Resources and Services Administration 9/03/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $159,032 ARRA- State Primary Care Offices This grant will increase MarylandG??s Primary Care Office ability to coordinate activities toward strengthening the primary care workforce through the following activities: 1. Implement a PCO newsletter 2. Draft, finalize and distribute a PCO annual r
This spending item is part of a $341,914 allocation. See details
Health Resources and Services Administration 9/11/2009
UNIVERSITY OF MARYLAND $158,191 Trans-NIH Recovery Act Research Support 'The ongoing project (CA197331) as well as the new work proposed in this competitive revision application addresses many important public health concerns including providing drugs to treat several cancers including malignant melanoma. This work also provi
This spending item is part of a $376,297 allocation. See details
National Institutes of Health 9/17/2009
BALTIMORE CITY HEALTHY START INC $155,353 Trans-NIH Recovery Act Research Support This is an administrative supplement awarded with American Recovery and Reinvestment Act (ARRA) funds. This award provides additional funding for Grant # U01HD044207-08. These funds were rebudgeted and approved for a retention specialist, two interviewe National Institutes of Health 9/22/2010
JOHNS HOPKINS UNIVERSITY, THE $152,453 Trans-NIH Recovery Act Research Support The overarching goal of this study is to test the role of pain, illicit drug use, and symptoms of depression and anxiety in the misuse of opioids and psychoactive medications within an existing cohort of men who have sex with men (MSM) participating in th
This spending item is part of a $330,796 allocation. See details
National Institutes of Health 5/04/2009
CHASE BREXTON HEALTH SERVICES, INC $151,706 ARRA - Community Health Applied Research Network The Fenway Institute Research Node aims to 1. Develop infrastructure for comparitive effectiveness research designed to improve the care and treatment of individuals with HIV/AIDS in a network of community health centers serving diverse patient populat... Show more
This spending item is part of a $1,983,468 allocation. See details
Health Resources and Services Administration 8/25/2010
JOHNS HOPKINS UNIVERSITY, THE $150,409 ARRA - Prevention and Wellness - Leveraging National Organizations ARRA Prevention and Wellness -- Leveraging National Organizations
This spending item is part of a $1,112,010 allocation. See details
Health and Human Services, Department of 7/13/2010
UNIVERSITY OF MARYLAND $150,000 Trans-NIH Recovery Act Research Support Deterioration of cartilage in adults due to trauma or disease is a major health issue in industrialized nations. Because cartilage lacks a regenerative ability, the therapeutic approach of creating cartilage implants in vitro has recently been put forward National Institutes of Health 9/09/2009
UNIVERSITY OF MARYLAND $150,000 Trans-NIH Recovery Act Research Support Highly active antiretroviral therapy (HAART) has dramatically increased life expectancy in HIV infection and by 2015 more than half of HIV patients in the U.S. will be older than 50. Elderly HIV patients often experience comorbidities such as neuropsychia National Institutes of Health 7/22/2009
UNIVERSITY OF MARYLAND $150,000 Trans-NIH Recovery Act Research Support The mission of the University of Maryland Marlene and Stewart Greenebaum Cancer Center is to undertake innovative basic and clinical research which will impact the understanding and treatment of cancer around the world and to provide state-of-the-art clin National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $150,000 Trans-NIH Recovery Act Research Support ChiLDREN is the Childhood Liver Disease Research and Education Network. At our site, Johns Hopkins University, we are actively recruiting and enrolling into the studies which compose ChiLDREN, including PROBE, START, BASIC, LOGIC, and MITOHEP. At the pres National Institutes of Health 2/17/2010
JOHNS HOPKINS UNIVERSITY, THE $149,994 Trans-NIH Recovery Act Research Support The Gastroparesis Clinical Research Consortium (GpCRC) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to focus on the etiology, natural history, and therapy of gastroparesis. The goal of this consortium is to National Institutes of Health 8/31/2009
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $149,084 Trans-NIH Recovery Act Research Support This is a partial award for the consortium with the Hugo W. Moser Research Institute at Kennedy Krieger effective 9/30/09. These supplemental funds are intended to accelerate the pace of biomarker discovery for FSHD therapeutics and will be targeted spec
This spending item is part of a $342,766 allocation. See details
National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $148,984 Trans-NIH Recovery Act Research Support To create algorithmic tools that aid basic and clinical neuroscientists in the analysis of variability in anatomical structures at different scales. The overall aim is to integrate 3D Slicer application and ITK software library with the statistical shape National Institutes of Health 8/10/2009
UNIVERSITY OF MARYLAND $148,245 Trans-NIH Recovery Act Research Support The overall goal of this application is to define the factors that shape antiviral T and B cell immunity and delineate the mechanisms by which these factors operate. We have focused on three factors that could shape effector and memory lymphocyte differen
This spending item is part of a $161,177 allocation. See details
National Institutes of Health 9/21/2009
UNIVERSITY OF MARYLAND $148,230 Trans-NIH Recovery Act Research Support Success of corneal transplant is dependent on high corneal endothelial (CE) cell density maintained immediately after surgery and thereafter. CE cells die either by acute necrosis, which initiates detrimental inflammatory responses, or by a slow programme National Institutes of Health 9/01/2009
JOHNS HOPKINS UNIVERSITY, THE $147,600 Trans-NIH Recovery Act Research Support The competitive award was requested to explore the role of mitochondria in HIV neuropathy and specifically the interaction between HIV envelope protein gp120 and mitochondrial function in causing distal axonal degeneration. We have already obtained prelim National Institutes of Health 9/25/2009
JOHNS HOPKINS UNIVERSITY, THE $147,600 Trans-NIH Recovery Act Research Support This project, entitled ?Longitudinal study of membrane lipids: Pre-clinical Alzheimer?s disease biomarkers?, will: (1) Characterize the between-individual variability of serum lipids (e.g. ceramides, sphingomyelins, 24S-hydroxycholesterol (24S-OHC), or F2 National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $147,044 Trans-NIH Recovery Act Research Support This award supports the Expansion of the original Acute Myeloid Leukemia (AML)Therapeutically Applicable Research to Generate Effective Treatmens (TARGET) cohort to include 50 relapse specimens as well as matching diagnostic/remission specimens from 30 pa
This spending item is part of a $976,412 allocation. See details
National Institutes of Health 9/22/2010
JOHNS HOPKINS UNIVERSITY, THE $143,500 Trans-NIH Recovery Act Research Support Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The LCMC member
This spending item is part of a $4,894,665 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $142,490 Trans-NIH Recovery Act Research Support Treatment rates vary dramatically across patients grouped by race, age, and gender. If treatment effects are heterogeneous across patients, though, it is not clear from treatment rate comparisons alone whether treatment rates should be increased or decrea
This spending item is part of a $1,458,033 allocation. See details
National Institutes of Health 9/24/2010
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $142,120 Trans-NIH Recovery Act Research Support The lifespan of adults with intellectual disability has been dramatically extended during the second half of the Twentieth Century. Advances in medicine, public health, early intervention, nutrition and habilitative technologies have contributed to this
This spending item is part of a $580,470 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $141,696 Trans-NIH Recovery Act Research Support This is a supplemental award to the main NIH grant which seeks to understand how the Chd1 remodeler moves nucleosomes through biophysical and biochemical analyses. A major component of this study focuses on obtaining structural snapshots of Chd1 and Chd1- National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $141,036 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $139,974 Trans-NIH Recovery Act Research Support Over the last years we have characterized transcription factors IRF-5, studied the regulation of its expression, and its role in the innate antiviral response. We were the first and only group that cloned and comprehensively analyzed properties of human I National Institutes of Health 7/06/2010
JOHNS HOPKINS UNIVERSITY, THE $139,868 Trans-NIH Recovery Act Research Support This proposal requests funds for the purchase of an AutoGenFlexSTAR DNA extraction instrument that will be dedicated to the molecular genetic and genetic epidemiology needs of four NIH-funded Major Users on the Bayview campus of the Johns Hopkins Universi National Institutes of Health 4/22/2010
UNIVERSITY OF MARYLAND $139,842 Trans-NIH Recovery Act Research Support High-dose chemotherapy and autologous stem cell transplantation (ASCT) provides myeloma patients with the best opportunity for complete remission and long-term survival. However, relapses are common and the likelihood of cure is probably no better than 10 National Institutes of Health 8/31/2009
UNIVERSITY OF MARYLAND BALTIMORE COUNTY $138,374 Trans-NIH Recovery Act Research Support Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), chlorobenzenes and dioxins remain an environmental health threat. New and innovative ways of detoxifying these compounds removing them from the environment are needed. This
This spending item is part of a $287,050 allocation. See details
National Institutes of Health 9/06/2009
JOHNS HOPKINS UNIVERSITY, THE $137,542 Trans-NIH Recovery Act Research Support The need to develop acceptable, available Point-of-Care-Tests (POCT) for identifying Sexually Transmitted Diseases (STDs) in at-risk populations is significant. In the United States, 5 of the top 10 reportable diseases are STDs and, per year, there are >1 National Institutes of Health 9/18/2009
UNITED WAY OF CENTRAL MARYLAND, INC., THE $137,198 ARRA - Community Services Block Grant Community Services Block Grant ARRA funding provides economic stimulus while furthering the mission under CSBG to promote the economic and social well-being of children, youth, families and communities. The funding is used for activities that contribute t
This spending item is part of a $13,719,817 allocation. See details
Administration for Children and Families 4/10/2009
JOHNS HOPKINS UNIVERSITY, THE $137,135 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The Cancer Genome Atlas (TCGA) project holds promise for a comprehensive understanding of human cancer through the application of genomic technologies. However, current cancer genomic analytical and visualization techn
This spending item is part of a $829,118 allocation. See details
National Institutes of Health 9/23/2010
JOHNS HOPKINS UNIVERSITY, THE $136,594 Trans-NIH Recovery Act Research Support The Multicenter AIDS Cohort Study (MACS), a comprehensive cohort study ongoing since 1984, has contributed to the understanding of the natural history of HIV infection and the impact of highly active antiretroviral therapies (HAART). Combining genetic, vi National Institutes of Health 6/02/2010
UNIVERSITY OF MARYLAND $136,000 ARRA ? Equipment to Enhance Training for Health Professionals Project Goals: The Video Observation for the Improvement and Evaluation of Resident Skills (VOI-ERS) program is an equipment-based curriculum that is designed to substantially enhance resident skills in key areas that are essential to impr... Show more Health Resources and Services Administration 9/07/2010
UNIVERSITY OF MARYLAND $135,693 Trans-NIH Recovery Act Research Support There is increasing evidence that antibodies targeting the CD4 induced (CD4i) epitopes on the HIV envelope spike can facilitate control of viremia and quite possibly protection from transmission after exposure (reviewed in (1, 2)). We have developed a gp1 National Institutes of Health 8/27/2010
JOHNS HOPKINS UNIVERSITY, THE $135,300 Trans-NIH Recovery Act Research Support Coordinate Regulation of Nuclear DGK-q and PLD. There are two consequences of this finding for the studies proposed in our funded proposal. First, studies in our awarded proposal were designed to localize DGK-q to the nucleus in order to examine the effec National Institutes of Health 9/23/2009
UNIVERSITY OF MARYLAND $134,552 Trans-NIH Recovery Act Research Support Type 1 interferons (IFNs) were discovered as mediators of host antiviral functions, and were recently shown to play essential roles in the innate immune response to nonviral pathogens. Established effectors of IFN antiviral action may thus serve previousl National Institutes of Health 7/23/2010
JOHNS HOPKINS UNIVERSITY, THE $132,053 Trans-NIH Recovery Act Research Support The Epilepsy Phenome/Genome Project is investigating how genes influence the phenotypes of common and rare epilepsies and has proposed to accelerate collection of phenotypic information by hiring a research assistant at each clinical center.
This spending item is part of a $1,558,189 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF MARYLAND $131,748 Trans-NIH Recovery Act Research Support A collaborative team involving investigators led by the Institute of Human Virology-University of Maryland (IHV) will identify 115 pregnant women with acute HIV infection. Our long-term goal is to advance the understanding of mother-to-child transmission
This spending item is part of a $292,795 allocation. See details
National Institutes of Health 6/02/2010
JOHNS HOPKINS UNIVERSITY, THE $131,200 Trans-NIH Recovery Act Research Support Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), a disease affecting one third of the human population and causing around two million deaths every year. Standard TB treatment uses a combination of different antibiotics that target a
This spending item is part of a $406,500 allocation. See details
National Institutes of Health 7/26/2010
City of Baltimore $131,187 Aging Home-Delivered Nutrition Services for States ARRA provided funding for home delivered meal services. Established in 1972 under the Older American Act, the program provides meals for older americans in their homes.
This spending item is part of a $546,714 allocation. See details
Administration on Aging 3/18/2009
JOHNS HOPKINS UNIVERSITY, THE $131,079 Trans-NIH Recovery Act Research Support This award is supplemental funding through the American Recovery Act Administrative Supplement mechanism (NOT-OD-056) for an NIAID funded R21 grant, ?Testing Modified Approaches to Informed Consent? (1R21AI074005-01A1). This purpose of this supplement is National Institutes of Health 9/07/2010
UNIVERSITY OF MARYLAND $130,827 Trans-NIH Recovery Act Research Support The cytokine IL-4 is produced by TH2 lymphocytes, NKT cells, and by cells of the innate immune system including mast cells, and eosinophils. It was originally identified as a stimulator of B cell proliferation, but it is now clear that IL-4 can regulate p National Institutes of Health 7/06/2010
JOHNS HOPKINS UNIVERSITY, THE $129,675 Johns Hopkins has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of papillary thyroid carcinoma tissue (80 cases). These cases are all primary and untr National Institutes of Health 8/27/2010
UNIVERSITY OF MARYLAND $128,270 Trans-NIH Recovery Act Research Support The hippocampus is a brain region regulating two (2) divergent but related life functions; learning and memory and regulation of the hypothalamatic-pituitary-adrnenal stress axis. The rodent provides a powerful model for investigating the importance of th National Institutes of Health 8/17/2009
JOHNS HOPKINS UNIVERSITY, THE $127,736 Trans-NIH Recovery Act Research Support Unwanted childbearing has been hypothesized to have significant detrimental health, social and economic consequences for children and parents, and represents a primary justification for investment in family planning programs. While the literature supporti
This spending item is part of a $176,840 allocation. See details
National Institutes of Health 5/21/2009
UNIVERSITY OF MARYLAND $127,230 Trans-NIH Recovery Act Research Support Mammals use several chemosensory systems to detect and encode their chemical environment. How these systems discriminate relevant chemical cues is a major unresolved question. We hypothesize that differences in the stimulus selectivity of different popula National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $126,312 Trans-NIH Recovery Act Research Support Lung cancer is the leading cause of cancer-related death in the U.S. and will soon reach epidemic levels worldwide. Mortality from this disease could be reduced through the identification of high-risk individuals and the implementation of effective thera
This spending item is part of a $1,212,592 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $125,994 Trans-NIH Recovery Act Research Support Perhaps one half of disease gene alleles are the result of mutations in non-coding sequence, rather than in protein coding sequences. Understanding the nature of disease, developing reliable diagnostics for disease, and relating different alleles to diff
This spending item is part of a $253,425 allocation. See details
National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $125,259 Trans-NIH Recovery Act Research Support The CFAR Network of Integrated Clinical Systems (CNICS), headquartered at UAB, was funded in September 2006 via the R24 mechanism. This supplement is to fund increased capacity for sample repositorys at UAB and each of the designated CNICS sites through
This spending item is part of a $1,825,789 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $122,456 Trans-NIH Recovery Act Research Support The Study to Help the AIDS Research Effort (SHARE) was funded by NIAID and NCI in 1983 to study the natural history of infection with human immunodeficiency virus, type 1 (HIV). SHARE, along with similar sites in Chicago, Pittsburgh, and Los Angeles, form National Institutes of Health 6/21/2010
UNIVERSITY OF MARYLAND $121,824 Trans-NIH Recovery Act Research Support In response to and in anticipation of seasonal changes in natural light, many animals manifest marked seasonal changes in physiology and behavior, such as those related to hibernation, breeding and migration. Although humans have increasingly (but far fro National Institutes of Health 9/20/2010
JOHNS HOPKINS UNIVERSITY, THE $121,619 Trans-NIH Recovery Act Research Support This proposal ?A Novel Ligand for PBR Imaging? is to investigate neuroinflammation in HIV dementia using a novel translocator protein (TSPO) ligand known as [11C]DPA-713. Currently, the ligand used most commonly for evaluating PBR binding is [11C]-R-PK111 National Institutes of Health 3/19/2010
JOHNS HOPKINS UNIVERSITY, THE $121,619 Trans-NIH Recovery Act Research Support This proposal ?A Novel Ligand for PBR Imaging? is to investigate neuroinflammation in HIV dementia using a novel translocator protein (TSPO) ligand known as [11C]DPA-713. Currently, the ligand used most commonly for evaluating PBR binding is [11C]-R-PK111 National Institutes of Health 3/19/2010
JOHNS HOPKINS UNIVERSITY, THE $121,301 Trans-NIH Recovery Act Research Support We are currently in the second year of a five-year R01 grant (DC007695), titled 'Development of the Calyx of Held'. In this competing revision, we propose to extend the scope of and implement new technologies for our investigation of neural circuit forma
This spending item is part of a $480,900 allocation. See details
National Institutes of Health 9/18/2009
UNIVERSITY OF MARYLAND $119,372 Trans-NIH Recovery Act Research Support Hematopoiesis is the development and formation of all blood cell types. All peripheral blood cells are derived from pluripotential stem cells. These cells are capable of both self-renewal and sequential commitment to the diverse blood cell lineages. The p National Institutes of Health 11/18/2009
JOHNS HOPKINS UNIVERSITY, THE $118,800 Trans-NIH Recovery Act Research Support Award description: A fundamental question in neuroscience is to understand how inputs from our hands, eyes and ears are processed in the central nervous system. At the input level for each sensory system are arrays of receptors that are sensitive to diffe National Institutes of Health 8/17/2009
JOHNS HOPKINS UNIVERSITY, THE $117,968 Trans-NIH Recovery Act Research Support ?Genetic models of retinal degeneration? The goals of the parent grant are to establish new retinal degeneration models to explore strategies for suppressing retinal cell death. To do so, we are using the fruit fly as an animal model, since many of the pr National Institutes of Health 8/04/2009
CENTER FOR MEDICAL TECHNOLOGY POLICY OF MARYLAND, INC, THE $117,629 Trans-NIH Recovery Act Research Support Numerous genomic applications for cancer have become available offering the promise of effective and efficient cancer care tailored to the genetic profile of the patient or disease?Genomics and Personalized Medicine (GPM). The current regulatory structure
This spending item is part of a $4,000,000 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $117,236 Trans-NIH Recovery Act Research Support Although frequently predicted to play critical roles in regulatory control, the nature and identity of functional noncoding sequences require comprehensive investigation. The inability to readily impute the functions of noncoding sequences, or the impact National Institutes of Health 9/09/2009
JOHNS HOPKINS UNIVERSITY, THE $116,861 Trans-NIH Recovery Act Research Support This diversity administrative supplement is being requested to support the continued research and career development of my graduate student, Alissa Richmond. Alissa is a fourth-year African-American graduate student pursuing a Ph.D. degree in the Biology National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $115,965 Trans-NIH Recovery Act Research Support The expanding availability of genome wide information on single nucleotide polymorphism (SNP) variants that increase risk for common diseases has sparked public debate about whether such information is useful for patients and health care providers. Unlike National Institutes of Health 9/20/2010
UNIVERSITY OF MARYLAND $115,388 Trans-NIH Recovery Act Research Support The proposed study builds upon findings from the parent grant and expands the scope of its specific aims, research design, and methods. Specifically, the focus of the parent grant is to apply high throughput genomic approaches in human samples to localize National Institutes of Health 9/14/2009
JOHNS HOPKINS UNIVERSITY, THE $115,224 Trans-NIH Recovery Act Research Support Project Title: Sleep in Rats: From Conceptualization to Measurement, Analysis and Interpretation My short-term goal for the duration of this 12-month Career Development Award is to build a substantial knowledge base regarding sleep from conceptualization National Institutes of Health 9/17/2010
JOHNS HOPKINS UNIVERSITY, THE $114,800 Trans-NIH Recovery Act Research Support Acting on multiple tissue types, adiponectin (Adipo) exerts insulin-sensitizing and cardiovascular protective effects. The physiological and/or clinical implications are that the plasma level of Adipo is negatively related to adiposity, insulin resistance
This spending item is part of a $434,200 allocation. See details
National Institutes of Health 5/15/2009
JOHNS HOPKINS UNIVERSITY, THE $114,660 Trans-NIH Recovery Act Research Support Chronic Kidney Disease is a silent epidemic affecting more than 10 million Americans. The burden of morbidity and mortality associated with chronic kidney disease derives from the frequent progression of chronic kidney disease to end-stage renal disease ( National Institutes of Health 9/02/2009
JOHNS HOPKINS UNIVERSITY, THE $114,027 Trans-NIH Recovery Act Research Support Project Title: A Six-Month, RCT of Probuphine Safety and Efficacy in Opioid Addiction. We are conducting a six-month, randomized, placebo and active-controlled, multicenter clinical trial of Probuphine in patients with opioid dependence for the purpose
This spending item is part of a $7,586,848 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $113,259 Trans-NIH Recovery Act Research Support This is an Administrative Supplement Award for our collaborative project with Dr. Pei Tang at University of Pittsburgh School of Medicine to add Nuclear Magnetic Resonance (NMR) approach into our study. In this project, we will systematically investigate National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $113,100 Trans-NIH Recovery Act Research Support Macrophages are central to our innate immune responses to infection and malignancy. Bacterialproducts, such as Gram negative lipopolysaccharide (LPS), and cytokines, such as interferons (IFNs),program the expression of an array of pro- and anti-inflammato National Institutes of Health 8/13/2009
UNIVERSITY OF MARYLAND $113,100 Trans-NIH Recovery Act Research Support Monocytes and macrophages sense pathogens, tumors, tissue damage, and host-derived mediators in their environment and respond by differentiating into distinct functional phenotypes that mediate host innate immune responses. However, the process of macroph National Institutes of Health 6/28/2010
BALTIMORE, CITY OF $113,011 ARRA Health Center Integrated Services Development Initiative[g1] This project funded one staff person to meet the spikes in demand to serve uninsured populations at two School-Based Health Centers in Baltimore City. Health Resources and Services Administration 3/27/2009
BALTIMORE, CITY OF $113,011 ARRA Health Center Integrated Services Development Initiative[g1] The Increased Demand for Services project funds one staff person to meet the spikes in demand to serve uninsured and underinsured populations at two School-Based Health Centers in Baltimore City. The implementation of this project allo... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF MARYLAND $112,830 Trans-NIH Recovery Act Research Support Quality sleep is imperative for the maintenance of good health. Persons suffering from sleep disturbances are not only fatigued but have impaired memory and learning, increased stress and anxiety and decreased quality of daily life. Sleep disturbances are National Institutes of Health 7/16/2009
UNIVERSITY OF MARYLAND $112,350 Trans-NIH Recovery Act Research Support Cancer in Maryland, and its impact on the health of minority and underserved rural populations, is a particularly serious health care dilemma. In fact, Maryland now ranks 7th nationally in cancer incidence, and significant disparities are seen between Afr National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $111,771 Trans-NIH Recovery Act Research Support PTH is the primary regulator of calcium homeostasis and bone metabolism in mammals. Its signaling system has served as a major target for the development of novel anabolic therapeutic approaches for osteoporosis. However, the exact mechanisms by which PTH National Institutes of Health 4/07/2010
JOHNS HOPKINS UNIVERSITY, THE $109,913 Trans-NIH Recovery Act Research Support This award sustains and extend the characterization of parkin interacting substrates. In particular this supplement is allowing the continuation of important studies focused on the identification and characterization of the Parkin Interacting Substrate (P National Institutes of Health 8/17/2009
JOHNS HOPKINS UNIVERSITY, THE $109,632 Tissue Repository Site for MTA and DA National Institutes of Health 3/24/2010
PUBLIC HEALTH DATA STANDARD CONSORTIUM $109,467 Trans-NIH Recovery Act Research Support North American AIDS Cohorts Collaboration on Research and Design A disturbing increase in the incidence of non-AIDS-defining conditions including renal disease, metabolic and cardiovascular disease, and malignancies has been observed in recent years, and
This spending item is part of a $7,312,062 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $109,006 Trans-NIH Recovery Act Research Support This project addresses two major bioinformatics problems: the development of better software for finding genes in eukaryotic genome sequences, and the development of genome assemblers for large shotgun sequencing projects. The gene finding project will pu National Institutes of Health 9/28/2011
JOHNS HOPKINS UNIVERSITY, THE $106,754 Trans-NIH Recovery Act Research Support During the past funding on this award, we have generated strong data to support the conclusion that the macrophage ubiquitination-proteasome pathway functions as a key regulator of LPS-induced signaling through Toll-like receptor 4 (TLR4). In addition, we
This spending item is part of a $327,700 allocation. See details
National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $105,937 Trans-NIH Recovery Act Research Support Hopkins Digestive Diseases Basic Research Development Center (DDBRDC) services 30 Hopkins PIs and has as its goal improving the research in gastroenterology done at JHUSOM. Due to the success of this Core Center we are overwhelmed in use of our resources National Institutes of Health 7/21/2009
JOHNS HOPKINS UNIVERSITY, THE $104,750 Trans-NIH Recovery Act Research Support Rheumatoid arthritis (RA) is the most common type of inflammatory arthritis; while there are now many effective medications to treat it, these drugs vary greatly in cost (up to $15,000/year) and side effects and there is no way to predict which drug is be
This spending item is part of a $3,344,252 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $103,136 Trans-NIH Recovery Act Research Support The 'Utilization of Principles of Community-Based Participator Research (CBPR) and Concept Mapping to Foster and Inform Community Engaged Research' project is an important initiative that will further increase awareness about the community based participa
This spending item is part of a $599,968 allocation. See details
National Institutes of Health 8/24/2009
JOHNS HOPKINS UNIVERSITY, THE $101,121 Trans-NIH Recovery Act Research Support There is a growing need for investigators who are trained in biomedical computing and related fields as they directly relate to application domains, including health care delivery, basic biomedical research, clinical and translational research and public National Institutes of Health 8/20/2009
UNIVERSITY OF MARYLAND $100,064 NCI's Community Cancer Centers Program (NCCCP) - The network of community hospitals is a complex pilot program whose mission is, through research, to determine ways to bring state of the art cancer care and clinical trials to patients in their local comm
This spending item is part of a $75,135,000 allocation. See details
National Institutes of Health 9/04/2009
JOHNS HOPKINS UNIVERSITY, THE $100,040 Trans-NIH Recovery Act Research Support Persons in the US with end stage renal disease (ESRD) have an annual mortality rate of over 20% and an age-specific death rate from cardiovascular disease that is 10-100 times higher than the general population. Much of this excess mortality is due to sud National Institutes of Health 9/30/2010
UNIVERSITY OF MARYLAND $100,001 Trans-NIH Recovery Act Research Support MicroRNAs bind to sites in target mRNAs' 3'UTR and (principally) inhibit translation to protein. Since binding of microRNAs does not depend on full complementarity with their target sequences, microRNAs can bind to and block protein translation of many di National Institutes of Health 1/20/2010
JOHNS HOPKINS UNIVERSITY, THE $100,000 Trans-NIH Recovery Act Research Support Lung involvement is currently the leading cause of morbidity and mortality in scleroderma (SSc) patients. Interstitial lung disease (ILD) is the most common pulmonary manifestation and may result from an abnormal immune response carried out by pro-fibroti National Institutes of Health 9/18/2009
UNIVERSITY OF MARYLAND $100,000 Trans-NIH Recovery Act Research Support The overarching goals of this supplemental application are: 1) accelerate the tempo of studies outlined in the parent application to elucidate the molecular mechanisms responsible for polarized targeting of a kidney potassium channel that helps control po National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $100,000 Trans-NIH Recovery Act Research Support The ARRA was a supplement to R01GM62437 which relates to basic science research on enzymes that are involved in epigenetics. Specifically, the award covered the purchase of major equipment used to allow more rapid progress toward achieving the specific ai National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $100,000 Trans-NIH Recovery Act Research Support There are greater than 1,000,000 new cancer cases per year in the United States and cancer deaths exceed 500,000 annually. The acquisition of drug resistance in tumors is an ongoing problem in cancer therapy. Therefore, our broad aim is to understand the National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $100,000 Trans-NIH Recovery Act Research Support Cyclic 3',5'-adenosine monophosphate (cAMP), the classical second messenger, regulates many diverse cellular functions. Although much has been learned about cAMP and cAMP-dependent protein kinase (PKA), there are still large gaps in our understa National Institutes of Health 1/14/2010
NOVAK BIRCH, INC. $100,000 Comprehensive support in providing exhibit and booth support at key public engagements. Novak Birch provides event management consulting, logistical support for conference year, support with graphics and signage production, inventory of publications and g Health Care Financing Admin. (was Medicare and Medicaid Serv.) 4/29/2011
UNIVERSITY OF MARYLAND $99,992 Trans-NIH Recovery Act Research Support In multicellular organisms, genomic stability and integrity is maintained by the combined actions of an accurate DNA replication machinery and a complex network of DNA repair pathways. DNA joining is an essential step in DNA replication, in DNA excision r National Institutes of Health 12/11/2009
JOHNS HOPKINS UNIVERSITY, THE $99,950 Trans-NIH Recovery Act Research Support Of the over 200,000 men estimated to be diagnosed with prostate cancer in 2010 in the U.S, almost one half will undergo radical prostatectomy (RP) for treatment of their disease. As many as 25% or more men who undergo this treatment will experience a re-e National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $99,921 Trans-NIH Recovery Act Research Support The unique property of polycystin-1 (large size, transmembrane nature and low level of expression of the protein) makes the analyses of the protein a great challenge. The proposed biochemical characterization of the complex polycystin-1 products using the National Institutes of Health 12/03/2009
JOHNS HOPKINS UNIVERSITY, THE $99,876 Trans-NIH Recovery Act Research Support Sensory nerves in the esophagus are essential for the regulation of its physiological function. Sensory nerves also mediate conscious sensations (heartburn, pain) and defensive reflexes from the esophagus. Perverted function of esophageal sensory nerves m National Institutes of Health 9/09/2009
JOHNS HOPKINS UNIVERSITY, THE $99,739 Trans-NIH Recovery Act Research Support Research Equipment for the Advancement of Science: This supplement grant is to purchase equipment that will significantly increase our capacities to pursue the research aims of the parent application R01-DC005808 ('Auditory-Vocal Interaction Mechanisms'). National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $99,710 Trans-NIH Recovery Act Research Support The Biochemical Basis for the Mechanics of Cytokinesis This grant supports our work on the mechanics of cell division particularly focusing on how forces affect the biochemistry of actin crosslinking proteins. We are elucidating the signaling pathways tha National Institutes of Health 1/14/2010
UNIVERSITY OF MARYLAND $99,613 Trans-NIH Recovery Act Research Support One of the most debilitating neurological complications of HIV infection is painful peripheral neuropathy (PPN) associated with nucleoside reverse transcriptase inhibitors (NRTIs). The predominant symptom, excruciating and unremitting pain, is resistant t National Institutes of Health 5/13/2010
UNIVERSITY OF MARYLAND $99,554 Trans-NIH Recovery Act Research Support This administrative supplement supports ARRA goals for equipment purchase of an IVR System to support conduct of cancer health disparities research and training of junior investigators on CHD research methods Skills gained will be relevant for career deve National Institutes of Health 9/14/2009
JOHNS HOPKINS UNIVERSITY, THE $99,292 Recovery Act Comparative Effectiveness Research - AHRQ This R13 Large Conference Grant from the Agency for Healthcare Research and Quality (AHRQ) supports the United States Cochrane Center (USCC) in collaboration with the consumer advocacy coalition, Consumers United for Evidence-based Healthcare (CU... Show more Agency for Healthcare Research and Quality 9/24/2009
UNIVERSITY OF MARYLAND $99,262 Trans-NIH Recovery Act Research Support One of the most debilitating neurological complications of HIV infection is painful peripheral neuropathy (PPN) associated with nucleoside reverse transcriptase inhibitors (NRTIs). The predominant symptom, excruciating and unremitting pain, is resistant t National Institutes of Health 9/01/2009
UNIVERSITY OF MARYLAND $98,790 Trans-NIH Recovery Act Research Support This competitive supplement application proposes a genome wide association study to engage in discovery to identify potential novel pathways explanatory of the progression of renal disease.
This spending item is part of a $2,100,000 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF MARYLAND $98,667 Trans-NIH Recovery Act Research Support Sustained hyperglycemia from diabetes causes catastrophic damage to many organs and tissues. An emerging point of view is focused on the rise in blood glucose following a meal. These blood glucose levels can be very high, and the peak concentration is mor National Institutes of Health 2/01/2010
JOHNS HOPKINS UNIVERSITY, THE $97,890 Trans-NIH Recovery Act Research Support The overall goal of the parent grant is to perform cognitive neuroscience experiments using electrocorticographic ECoG recordings in human subjects (EEG recorded from the brain surface with electrodes surgically implanted for epilepsy surgery). These reco National Institutes of Health 8/17/2009
JOHNS HOPKINS UNIVERSITY, THE $97,757 Trans-NIH Recovery Act Research Support Despite an increase in the repertoire of cytotoxic and targeted therapies, the prognosis for patients with advanced malignancies remains poor. Recent work has supported a stem cell theory for cancer and suggests that an early tissue specific stem cell is National Institutes of Health 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $97,731 Trans-NIH Recovery Act Research Support We will establish the qualitative and quantitative potential of stem cells (SC) and committed progenitor cells of hematopoietic tissue (HSC) for the repair of damage to epithelial tissues. These studies are designed to examine the mechanisms responsible f National Institutes of Health 9/17/2009
HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. $97,651 Trans-NIH Recovery Act Research Support Supplemental funds for equipment purchases are requested to increase the tempo of scientific research funded under our parent grant, P30HD024061 which supports the Intellectual and Developmental Disabilities Research Center (IDDRC) of the Kennedy Krieger National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $97,500 Trans-NIH Recovery Act Research Support This is an administrative supplement request to support research in our Program Project grant P01-CA16519, Molecular and Cellular Basis of Tumorigenesis. This administrative supplement request represents an opportunity to increase the tempo of our researc National Institutes of Health 9/22/2009
UNIVERSITY OF MARYLAND $97,100 Trans-NIH Recovery Act Research Support The experiments in this proposal are designed to investigate the basis of changes in cognitive flexibility caused by normal aging. Subsets of elderly humans and rats appear to have difficulty changing behaviors when the likely outcomes of those behaviors National Institutes of Health 9/14/2010
JOHNS HOPKINS UNIVERSITY, THE $95,839 Trans-NIH Recovery Act Research Support PERCEPTIONS OF SOCIAL USEFULNESS/VALUE AS PREDICTORS OF HEALTH IN OLDER ADULTS The overall purpose of this project is to assess older adults' experience of both burdens and benefits as volunteers in a high-intensity volunteer program, the Experience Cor
This spending item is part of a $111,879 allocation. See details
National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $93,741 Trans-NIH Recovery Act Research Support Human immunodeficiency virus type -1 (HIV-1) infection is the commonest cause of dementia in adults less than 40 years of age. Alcohol is a common drug of abuse in HIV-infected patients that can worsen the decline of frontal lobe function that is associat National Institutes of Health 8/09/2010
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $93,310 ARRA - Prevention and Wellness--State Territories and Pacific Islands With the ARRA funding, the Center for Health Promotion, Education and Tobacco Use Prevention (CHP) will be able to expand and promote the Maryland Tobacco Quitline program through the following activities: 1) Create a position... Show more
This spending item is part of a $750,534 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
UNIVERSITY OF MARYLAND $92,130 Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation. See details
National Institutes of Health 9/14/2009
UNIVERSITY OF MARYLAND $90,804 Trans-NIH Recovery Act Research Support In our knowledge of the mechanism of sexual transmission of HIV-1 there is a very important gap. The population of HIV viruses soon after infection is, in most cases, monotypic; it is as if a single virus initiated infection. The population of viruses in National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $90,484 Trans-NIH Recovery Act Research Support The long-term goals of the project are to (1) Characterize HIV-related high-risk behaviors (heterosexual, drug abuse, homosexual) among commercial sex male clients (CSMCs) population; determine the prevalence and interacting effect of these behaviors, and National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $90,229 Trans-NIH Recovery Act Research Support The overarching goal of the proposed study is to improve communication among clinicians, patients, and family caregivers about a diagnosis of dementia. Specific aims. 1) Characterize physician, patient, and companion behaviors during a dementia diagnosis
This spending item is part of a $144,236 allocation. See details
National Institutes of Health 5/21/2009
JOHNS HOPKINS UNIVERSITY, THE $90,172 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (02) Bioethics and specific Challenge Topic, 02-HG-101: Informed consent and data access policies. The ethical, legal, and social issues (ELSI) underlying the development and implementation of state-sponsore
This spending item is part of a $899,991 allocation. See details
National Institutes of Health 9/25/2009
MORGAN STATE UNIVERSITY (INC) $90,058 Trans-NIH Recovery Act Research Support The program is focused on increasing the number of well-prepared and highly qualified under-represented minority students who can successfully compete for positions in graduate programs leading to the PhD degree in the behavioral or biomedical sciences. National Institutes of Health 7/01/2010
MORGAN STATE UNIVERSITY (INC) $90,058 Trans-NIH Recovery Act Research Support The program is focused on increasing the number of well-prepared and highly qualified under-represented minority students who can successfully compete for positions in graduate programs leading to the PhD degree in the behavioral or biomedical sciences. National Institutes of Health 7/01/2010
JOHNS HOPKINS UNIVERSITY, THE $88,235 Trans-NIH Recovery Act Research Support Diabetes Research and Training Center This application is in response to the NIH Notice NOT-OD-09-056. The Baltimore DRTC requests supplemental funding of programs that will benefit its ongoing mission to understand and treat diabetes and related diseases National Institutes of Health 5/10/2010
JOHNS HOPKINS UNIVERSITY, THE $86,676 Trans-NIH Recovery Act Research Support This project goals is to understand signaling complexes that form on the NHE3 C-terminus aa 475-589, the domain closest to the N-terminal transport domain. This part of the protein is necessary for regulated and basal trafficking of NHE3 to the plasma mem National Institutes of Health 8/31/2009
JOHNS HOPKINS UNIVERSITY, THE $86,363 Trans-NIH Recovery Act Research Support This award is entitled Fogarty ARRA Supplement for US Global Health Postdoctoral Scientist Support (American Recovery and Reinvestment Act of 2009, NOT-OD-056). It builds on over 20 years of collaboration between Johns Hopkins University (JHU) and Aga Kha National Institutes of Health 9/03/2009
JOHNS HOPKINS UNIVERSITY, THE $83,640 Trans-NIH Recovery Act Research Support Maturation functions of the HSV-1 tegument. Herpes simplex virus (HSV) assembles an icosahedral capsid and packages this structure with the viral genome in the nucleus. It then has to exit the nucleus using a complex envelopment/de-envelopment pathway tha National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $82,556 Trans-NIH Recovery Act Research Support C. glabrata is an important opportunistic pathogen causing mucosal infection in healthy individuals and disseminated infection in immunocompromised, primarily hospitalized, patients, responsible for approximately 20% of all candidemias. The Cormack lab is National Institutes of Health 8/11/2009
JOHNS HOPKINS UNIVERSITY, THE $82,000 Trans-NIH Recovery Act Research Support The current project is a B-Start grant that is being used to collect preliminary data to submit a R01. Specifically, hallucinogens are generally considered to be physiologically safe (i.e., they do not result in physiological dependence nor do they cause National Institutes of Health 6/01/2009
JOHNS HOPKINS UNIVERSITY, THE $82,000 Trans-NIH Recovery Act Research Support In India, cervical cancer is one of the leading causes of cancer in women, with age-standardized rates (ASR) that vary from 18 to 30 per 100,000. This is in contrast to the United States, where the ASR is as low as 3 per 100,000. The difference is primari
This spending item is part of a $170,250 allocation. See details
National Institutes of Health 8/14/2009
UNIVERSITY OF MARYLAND $81,270 Trans-NIH Recovery Act Research Support The recovery of useful hand function after stroke is a major scientific challenge for stroke treatment today particularly for those with more severe paresis. In this population recovery mechanisms may differ from those with mild hemiparesis and may involv National Institutes of Health 7/07/2010
JOHNS HOPKINS UNIVERSITY, THE $80,881 Trans-NIH Recovery Act Research Support This project addresses the need to protect active duty personnel and veterans from gonorrhoea. It is the next phase of an on-going program to develop a vaccine against gonococcal infection. This supplement is to add personnel to project tp dp the ELISAs
This spending item is part of a $184,066 allocation. See details
National Institutes of Health 4/05/2010
JOHNS HOPKINS UNIVERSITY, THE $80,519 Trans-NIH Recovery Act Research Support This award is an administrative supplement for an equipment purchase necessary to achieve the original goals of the P20GM078494 proposal. The equipment being purchased is a Laser Doppler Imaging system. National Institutes of Health 4/23/2010
JOHNS HOPKINS UNIVERSITY, THE $80,440 Trans-NIH Recovery Act Research Support An Interdisciplinary Approach to PKD2 Function:The long-term goal of this application is to achieve a better understanding of the normal cellular function of TRPP channels. TRPP proteins are a family of calcium permeant channels that are evolutionarily co National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $79,998 Trans-NIH Recovery Act Research Support The biggest challenge in fighting the obesity epidemic is developing better ways to help individuals that have lost weight maintain their weight loss over many years. This challenge grant provides funding to analyze follow-up data collected 2 -+ years fo
This spending item is part of a $996,603 allocation. See details
National Institutes of Health 9/23/2009
JOHNS HOPKINS UNIVERSITY, THE $79,969 Trans-NIH Recovery Act Research Support This award is an administrative supplement to grant DK080351. The supplement is designed to acquire 3 instruments that will enhance the performance of the scientific program proposed in the parent grant. National Institutes of Health 2/15/2010
UNIVERSITY OF MARYLAND $79,100 Trans-NIH Recovery Act Research Support The relevance of bladder urothelial cells (BUG) to human disease has traditionally been understood only in terms of urothelial cell carcinoma. However, there is exciting new literature highlighting the role of altered BUG structure and function in non-neo National Institutes of Health 11/19/2009
JOHNS HOPKINS UNIVERSITY, THE $77,685 Trans-NIH Recovery Act Research Support Adhesion and migration are fundamental cell processes that are disrupted in disease states:in some cases, these disruptions cause or exacerbate the disease. Research has shown that there are many pathways and proteins involved in regulating adhesion and m National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $77,273 Trans-NIH Recovery Act Research Support MCH is a major part of adaptive immune system. Thus, understanding the ancestral synteny of MHC in more details might acquire new insights on the primordial MHC structures and mechanisms vital for a functioning immune system and further reveal new insigh National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $76,211 Trans-NIH Recovery Act Research Support Articular cartilage damage is a growing problem with active and increasingly aging populations. Cartilage, which is critical for frictionless and painless joint motion, has little endogenous repair capability. Aging processes and trauma lead to cartilage National Institutes of Health 6/04/2009
UNIVERSITY OF MARYLAND $75,939 Trans-NIH Recovery Act Research Support Antibodies are highly useful reagents in biotechnological and biomedical applications, yet recombinant antibodies have their limitations. These include the complex architecture of their antigen-binding sites, which complicates the generation of synthetic
This spending item is part of a $187,500 allocation. See details
National Institutes of Health 6/17/2010
CARNEGIE INSTITUTION OF WASHINGTON $75,722 Trans-NIH Recovery Act Research Support The project aims to futher elucidate these two observations of the hormone - expressing PVN and SON neurons in order to better understand both hypothalamic development and fuction. National Institutes of Health 9/14/2009
JOHNS HOPKINS UNIVERSITY, THE $75,000 Trans-NIH Recovery Act Research Support This award partially funds the project entitled,informational and financial interventions to enhance African Americans? consideration of Live Kidney Donation/ Living Related Kidney Transplant . The parent award is funding the development and testing of a National Institutes of Health 9/28/2009
UNIVERSITY OF MARYLAND $75,000 Trans-NIH Recovery Act Research Support A Lassa vaccine in primates with AIDS. Lassa fever virus is a rodent-borne scourge in West Africa, and Lassa has been classified as a Category A biothreat in the US because of its lethality and aerosol-transmissibility. Efforts to control Lassa fever focu National Institutes of Health 9/01/2009
JOHNS HOPKINS UNIVERSITY, THE $75,000 ARRA - Prevention and Wellness--State Territories and Pacific Islands To address the alarming trend in cigar use by youth, CHP will focus on initiatives reducing access to and raising awareness of the dangers of cigar use. CHP will work with youth, young adult, and Statewide supporters, along with ... Show more
This spending item is part of a $863,360 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
JOHNS HOPKINS UNIVERSITY, THE $74,997 Trans-NIH Recovery Act Research Support The Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to characterize the natural history of the different phenotypes of nonalcoholic fatty liver National Institutes of Health 1/25/2010
JOHNS HOPKINS UNIVERSITY, THE $72,906 Trans-NIH Recovery Act Research Support Overweight is a serious public health problem that begins as early as toddlerhood, and has negative health and developmental consequences throughout life. Although caregiver-child interaction patterns influence children's growth, most overweight preventio
This spending item is part of a $2,010,457 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $72,743 Trans-NIH Recovery Act Research Support Mechanistic Studies of Nucleic Acid Damage and Their Application. The long term goal of this research is to understand how nucleic acids are oxidatively damaged, and to use this knowledge to design new therapeutic candidates and biotechnology tools. Nucle National Institutes of Health 1/21/2010
UNIVERSITY OF MARYLAND $72,289 Trans-NIH Recovery Act Research Support Chlamydial polymorphic membrane proteins (Pmps) are a newly identified family of Chlamydia-specific membrane proteins, whose role in chlamydial biology and pathogenesis is unknown. Genomic analysis of the pmp family of C. pneumoniae have revealed frameshi National Institutes of Health 5/10/2010
JOHNS HOPKINS UNIVERSITY, THE $71,965 Trans-NIH Recovery Act Research Support The project is a 4-celled factorial experiment designed to test the relative effects of separately and jointly introducing micro-credit (MC) and essential (health) services package (ESP) interventions on women's empowerment, economic well-being of th National Institutes of Health 11/19/2009
UNIVERSITY OF MARYLAND $70,711 Trans-NIH Recovery Act Research Support There are persistent questions regarding the evolution and function of the immune system. Previously studies performed in non-mammalian vertebrates have helped to reveal basic features of the immune system that are universal. In other cases, studies outsi National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $70,585 Trans-NIH Recovery Act Research Support This proposal is for a Rare Cancer Genetics Registry (RCGR). The proposal is being submitted for Challenge Area: 07: Enhancing Clinical Trials and specific Challenge Topic: Rare Disease Genetic Patient Registry: 07-OD(ORDR)-102. We will develop a registry
This spending item is part of a $987,770 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $70,571 Trans-NIH Recovery Act Research Support The parent grant for this supplemental proposal aims to understand the neural organization of auditory language perception/comprehension at the phonological, lexical,and sentence levels. It has two arms, functional imaging (fMRI) in healthy adults and beh
This spending item is part of a $291,380 allocation. See details
National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $70,000 Trans-NIH Recovery Act Research Support The maturation of peptide hormones within secretory tissues such as the pancreas, pituitary and adrenal requires the participation of specific proteolytic converting enzymes, the prohormone convertases, and small convertase binding proteins such as 7B2 an National Institutes of Health 12/03/2009
HOUSE OF RUTH MARYLAND, INC. $69,991 Trans-NIH Recovery Act Research Support The 'Utilization of Principles of Community-Based Participator Research (CBPR) and Concept Mapping to Foster and Inform Community Engaged Research' project is an important initiative that will further increase awareness about the community based participa
This spending item is part of a $599,968 allocation. See details
National Institutes of Health 8/24/2009
JOHNS HOPKINS UNIVERSITY, THE $69,756 Trans-NIH Recovery Act Research Support Novel forms of reward-related plasticity in the visual cortex are not only intriguing in terms of basic sensory coding mechanisms, but have direct relevance to our understanding of cue-drug association, an important facet of the complex problem of drug ad National Institutes of Health 5/07/2009
JOHNS HOPKINS UNIVERSITY, THE $69,700 Trans-NIH Recovery Act Research Support Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The LCMC member
This spending item is part of a $4,894,665 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $68,732 Trans-NIH Recovery Act Research Support Severe asthma, a heterogeneous disease consisting of related clinical phenotypes, generates high levels of morbidity, mortality and health care costs. The complexity and heterogeneity of the disorder have limited clinical advances. However, the NHLBI Seve
This spending item is part of a $3,489,267 allocation. See details
National Institutes of Health 9/25/2009
MANOLIS PAINTING, INC. $68,150 Construction Manager as Constructor at Risk services to renovation Building 10, F Wing in two phases: Phase A of the F Wing Renovation: Pre construction, construction, activation/occupancy and closeout; to convert 64,000 gsf of former patient care units o
This spending item is part of a $131,640,100 allocation. See details
National Institutes of Health 7/30/2010
JOHNS HOPKINS UNIVERSITY, THE $67,841 Trans-NIH Recovery Act Research Support Translation initiation is a central biological process. It is also a key point in the regulation of gene expression. Eukaryotic translation initiation is a potential target of anticancer, antiviral and antifungal drugs. Attempts to develop drugs targeting National Institutes of Health 7/16/2009
JOHNS HOPKINS UNIVERSITY, THE $67,043 Trans-NIH Recovery Act Research Support Title of project is ?Chloride channels in Lung Development?. Cystic Fibrosis is an orphan disease affecting 30,000 people in USA. The gene that causes CF is the CFTR, a cAMP-regulated chloride channel. The disease is fatal with no cure. This grant is deve National Institutes of Health 6/11/2009
UNIVERSITY OF MARYLAND $66,847 ARRA - Prevention and Wellness--State Territories and Pacific Islands To address the alarming trend in cigar use by youth, CHP will focus on initiatives reducing access to and raising awareness of the dangers of cigar use. CHP will work with youth, young adult, and Statewide supporters, along with ... Show more
This spending item is part of a $863,360 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
UNIVERSITY OF MARYLAND $66,823 Trans-NIH Recovery Act Research Support Investigate the mechanism of B-cell delivered tolerance in animal models, and then begin to translate these studies to the clinic using T Cells from MS patients exposed to B cells transdueced with MBP-Ig constructs in vitro. These studies will establish National Institutes of Health 9/17/2009
JOHNS HOPKINS UNIVERSITY, THE $66,750 Trans-NIH Recovery Act Research Support The association between Bcl-2 and cancer has been known for 20 years. But the biochemical mechanisms to explain why Bcl-2, found at translocation breakpoints in follicular lymphomas, why elevated Bcl-xL expression in many tumor types, and why herpes virus National Institutes of Health 12/18/2009
JOHNS HOPKINS UNIVERSITY, THE $66,420 Trans-NIH Recovery Act Research Support Our long-term objective is to understand the host factors that regulate the systemic inflammation andpathogenesis of sepsis, which affects 750,000 persons every year in United States alone and causes high mortality worldwide. We recently discovered a nove National Institutes of Health 8/27/2010
JOHNS HOPKINS UNIVERSITY, THE $65,725 Trans-NIH Recovery Act Research Support This administrative supplement to NCI grant R01CA120185 provided funds to purchase an Applied Biosystems (ABI) 7900HT real-time PCR machine which allows direct measurements of gene expression in cells and tissues. National Institutes of Health 9/04/2009
CENMED ENTERPRISES INC. $65,000 7900HT Fast Real Time 384 Well National Institutes of Health 6/29/2009
JOHNS HOPKINS UNIVERSITY, THE $64,996 Trans-NIH Recovery Act Research Support The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in National Institutes of Health 9/28/2009
UNIVERSITY OF MARYLAND $64,144 Trans-NIH Recovery Act Research Support This proposal is submitted in response to RFA-DK-06-501 for continuation of the Urinary Incontinence Treatment Network (UITN) Clinical Center at University of Maryland Baltimore (UMB). Phase II will focus on conduct of the Trial of Mid-Urethral Slings (TO
This spending item is part of a $190,000 allocation. See details
National Institutes of Health 9/30/2010
JOHNS HOPKINS UNIVERSITY, THE $63,953 Trans-NIH Recovery Act Research Support We requested funds to obtain an instrument that will allow us to accomplish the same goals described in the parent grant in more than 20-fold less time resulting in a significant acceleration of the pace of our scientific research. This request should als National Institutes of Health 9/21/2009
INTELLIGENT SUBSTRATES, INC. $63,791 Trans-NIH Recovery Act Research Support The long term goal of this project is to develop new technology that will allow rapid user- defined patterning of proteins on cell culture substrates at dimensions ranging from 50 nanometers to millimeters. Patterned cell culture substrates are emerging a
This spending item is part of a $96,755 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $63,750 Trans-NIH Recovery Act Research Support The purpose of this application is to enhance both the process and benefits of clinical andtranslational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying out scienti
This spending item is part of a $400,000 allocation. See details
National Institutes of Health 9/07/2009
JOHNS HOPKINS UNIVERSITY, THE $61,870 Recovery Act Comparative Effectiveness Research - AHRQ A network of 32 health services and intervention scientists affiliated with the HMO Research Network propose to build a national database for conducting comparative effectiveness research on treatment and on approaches to preventing diabetes mell... Show more
This spending item is part of a $8,920,115 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
JOHNS HOPKINS UNIVERSITY, THE $61,614 Trans-NIH Recovery Act Research Support The prevalence of food allergy has increased over the past 2 decades and food allergy now affects 3.5% :o 4% of the U.S. population. Peanut allergy, which is the single leading cause of severe and fatal foodnduced allergic reactions in the U.S., affects 1
This spending item is part of a $372,330 allocation. See details
National Institutes of Health 7/19/2010
PINNACLE COMMUNICATIONS RESOURCE COMPANY A LIMITED LIABILITY COMPANY $60,000 ARRA - Prevention and Wellness--State Territories and Pacific Islands To address the alarming trend in cigar use by youth, CHP will focus on initiatives reducing access to and raising awareness of the dangers of cigar use. CHP will work with youth, young adult, and Statewide supporters, along with ... Show more
This spending item is part of a $863,360 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
JOHNS HOPKINS UNIVERSITY, THE $59,368 Trans-NIH Recovery Act Research Support Vascular complications are a significant cause of morbidity and mortality in ADPKD. Interestingly it has been observed that there is a subset of families with ADPKD who also exhibit features of the Marfan syndrome (MFS).Our studies demonstrate that mice, National Institutes of Health 12/18/2009
UNIVERSITY OF MARYLAND $59,237 Trans-NIH Recovery Act Research Support This application addresses the broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic, 05-GM-101: Anesthesiology Clinical Pharmacology Sepsis Trauma, Burn, and Peri-operative Injury Wound Healing. Traumatic brain injury
This spending item is part of a $980,750 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $58,458 Trans-NIH Recovery Act Research Support Funds from this administrative supplement are being used to purchase the CFX96 Real-Time PCR Detection System (Bio-Rad Laboratories, Hercules, CA) including a computer, software, and essential SYBR green fluorescence reagents, as proposed in the supplemen National Institutes of Health 9/02/2009
UNIVERSITY OF MARYLAND $58,004 Trans-NIH Recovery Act Research Support One of the most striking effects reported by male and female users of methamphetamine, a highly addictive psychostimulant drug of abuse, is an increase in sexual libido and an insatiable need and urgency for sex. In addition, female methamphetamine users National Institutes of Health 5/07/2009
UNIVERSITY OF MARYLAND $57,617 Trans-NIH Recovery Act Research Support Osteoarthritis (OA) is the most common cause of arthritis. Approximately 21 million Americans have physician-diagnosed OA and many more have undiagnosed disease. Knee OA is responsible for as much chronic disability in the elderly as cardiovascular diseas
This spending item is part of a $4,430,735 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $57,500 To establish a coordinated process structured to meet previously-identified scientific needs for quantitative imaging biomarkers. The long-term objective is to establish processes and profiles that will lead to acceptance by the imaging community, clinica
This spending item is part of a $2,412,566 allocation. See details
National Institutes of Health 9/30/2010
JOHNS HOPKINS UNIVERSITY, THE $56,841 Trans-NIH Recovery Act Research Support An Interactive Web-Based Game for Collaborative Labeling of Medical Images. The proposed research investigates extension of established practices for volumetric labeling and web-based collaboration to create an innovative infrastructure for labeling. A us
This spending item is part of a $435,741 allocation. See details
National Institutes of Health 6/15/2009
UNIVERSITY OF MARYLAND $56,776 Trans-NIH Recovery Act Research Support Lassa virus (LASV) is the causative agent of Lassa Fever (LF), a zoonotic viral hemorrhagic fever endemic in West Africa responsible for wide spread disease and significant morbidity and mortality. There currently exists no vaccine against LF, while the n National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $56,521 Trans-NIH Recovery Act Research Support The parent grant (R37 DK42495-20) associated with this application focuses on the role of gap junctions that confer syncytial properties to renal medullary descending vasa recta (DVR) endothelium. DVR are microvessels, 12 to 15 micron branches of juxtamed National Institutes of Health 12/08/2009
AGING, MARYLAND DEPARTMENT OF $55,528 Aging Congregate Nutrition Services for States ARRA provided funding for congregate nutrition services. Established in 1972 under the Older American Act, the program provides meals for older americans in congregrate facilities such as seniors centers, adult day care centers,and faith based settings.... Show more
This spending item is part of a $1,110,512 allocation. See details
Administration on Aging 3/18/2009
JOHNS HOPKINS UNIVERSITY, THE $54,838 Trans-NIH Recovery Act Research Support Bayesian methods for (incomplete) longitudinal cancer data We continue work from our previous proposal in developing new Bayesian methodology for longitudinal cancer data with missingness. In the presence of missing data that is related to observed or
This spending item is part of a $219,927 allocation. See details
National Institutes of Health 5/13/2009
UNIVERSITY OF MARYLAND $54,574 Trans-NIH Recovery Act Research Support This project has obtained follow up photography of the fundus of CRIC patients. Analyisis of the photographs has been completed. We will be performing the statistical analysis of the results. This will allow us to investigate the relationship between pro
This spending item is part of a $1,464,614 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $54,360 Trans-NIH Recovery Act Research Support The CNRU of Maryland will focus on the influence of nutrition and exercise on risk for age-related chronic diseases, including obesity, type 2 diabetes, hypertension, cardiovascular disease (CVD), sleep disordered breathing, and osteoporosis. With the obe National Institutes of Health 7/13/2009
UNIVERSITY OF MARYLAND $54,200 Trans-NIH Recovery Act Research Support The University of Maryland Baltimore Institutional Review Board - National Health Research Ethics Committee of Nigeria (NHREC) Collaborative Capacity Building Initiative (UMBINN) is a program designed to enhance the capacity of the two ethics review commi National Institutes of Health 9/24/2010
JOHNS HOPKINS UNIVERSITY, THE $54,000 Trans-NIH Recovery Act Research Support This project is a Research Development Support supplement for a Career Development Award (Parent Grant K08 DK078046-02 - Matrilysin regulation in colonic epithelial cells and role in barrier function). The descriptive title of this project is Intestine-sp National Institutes of Health 8/24/2009
UNIVERSITY OF MARYLAND $54,000 Trans-NIH Recovery Act Research Support The candidate is a promising young investigator with board certifications in Internal Medicine and Infectious Disease, and a Masters of Science degree in Clinical Investigation, who has made a substantial commitment to an academic career in patient-orient National Institutes of Health 9/11/2009
JOHNS HOPKINS UNIVERSITY, THE $54,000 Trans-NIH Recovery Act Research Support Roles for Phospholipase A2 Signaling in Prostate Development: The parental K08 award?s hypothesis focused on the role of cytoplasmic phospholipase A2 (cPLA2) in prostate development. This enzyme is a potent regulator of the inflammatory response and one o National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $54,000 Trans-NIH Recovery Act Research Support While the prognosis of early stage head and neck squamous cell carcinoma is excellent with standard surgical and chemo-radiation treatment strategies, effective treatment modalities for advanced or recurrent disease are lacking. Various immunotherapy clin National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $54,000 Trans-NIH Recovery Act Research Support In the course of a rewarding and productive 5-year K-23 award dedicated to the research and discovery of biomarkers for prostate disease, we identified what may be one of the first molecular markers of benign prostatic hyperplasia (BPH), a disease that af National Institutes of Health 1/18/2010
UNIVERSITY OF MARYLAND $52,500 ARRA - Prevention and Wellness--State Territories and Pacific Islands To address the alarming trend in cigar use by youth, CHP will focus on initiatives reducing access to and raising awareness of the dangers of cigar use. CHP will work with youth, young adult, and Statewide supporters, along with ... Show more
This spending item is part of a $863,360 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
UNIVERSITY OF MARYLAND $51,889 Trans-NIH Recovery Act Research Support We will employ a rat model of inflammatory pain to study interactions between glia, cytokines, and neurons and explore their significance in the central nervous system response to injury and the development of persistent orofacial pain conditions. The ou National Institutes of Health 9/22/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $51,660 ARRA - Immunization The Maryland Emerging Infections Program (EIP) will use these funds to support the ?13-valent Pneumococcal Conjugate Vaccine Effectiveness Study (PCV13)? and the on-going ?Quadrivalent Meningococcal Conjugate Vaccine Effectiveness Study (MCV4)?. The PCV1
This spending item is part of a $449,422 allocation. See details
Centers for Disease Control and Prevention 8/31/2009
UNIVERSITY OF MARYLAND $51,132 Trans-NIH Recovery Act Research Support To date, methadone-drug interactions is a field of research that is characterized asymmetrically among published scientific literature. The majority of reports focus intensively on characterization of how other drugs affect the metabolic & pharmacokinetic National Institutes of Health 5/21/2009
JOHNS HOPKINS UNIVERSITY, THE $50,167 Trans-NIH Recovery Act Research Support Factors Stabilizing RNA Structures (supplement) - The primary purpose of the proposed supplement is the replacement of an aging UV spectrophotometer we use for measuring the free energy of RNA folding transitions. The poor quality of the data and the down National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $50,000 Trans-NIH Recovery Act Research Support Clinical and Behavioral Determinants of CKD Disparities is an award to support the career development of Dr. Leigh E. Boulware at Johns Hopkins University School of Medicine. Through a structured didactic plan and the conduct of several studies to investi National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $50,000 Trans-NIH Recovery Act Research Support Antibiotic resistance is an increasing public health problem that is associated with considerable morbidity, mortality and costs. Given the reduced pace of antibiotic discovery and the approaching demographic shift towards an increasingly aged population, National Institutes of Health 9/01/2009
JOHNS HOPKINS UNIVERSITY, THE $50,000 Trans-NIH Recovery Act Research Support The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins has been participating in the planning activities associated with the project entitled ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring by providing appropriate clin National Institutes of Health 9/18/2009
JOHNS HOPKINS UNIVERSITY, THE $50,000 Trans-NIH Recovery Act Research Support Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic and frequently disabling intestinal inflammatory disorders that affect more than a million individuals in the US. One of the most dreaded compl National Institutes of Health 3/12/2010
UNIVERSITY OF MARYLAND $50,000 Trans-NIH Recovery Act Research Support This is a 5-year training plan for a mentored physician scientist in Gastroenterology and Hepatology. The Principal Investigator is a junior faculty member in the Division of Gastroenterology and Hepatology at University of Maryland School of Medicine (UM National Institutes of Health 1/20/2010
JOHNS HOPKINS UNIVERSITY, THE $50,000 Trans-NIH Recovery Act Research Support Global health research that involves human subjects in limited-resource setting countries continues to expand. Funding agencies such as National Institute of Health (NIH) are becoming more involved in ethically challenging scientific areas such as HIV/AID National Institutes of Health 9/29/2010
JOHNS HOPKINS UNIVERSITY, THE $50,000 Trans-NIH Recovery Act Research Support The objectives of the proposed studies are two-fold: 1) To investigate the mechanisms of the effects of cytokines and hormones on the regulation of rat class I alcohol dehydrogenase (ADH). These studies include characterization of trans-acting factors tha National Institutes of Health 8/09/2010
UNIVERSITY OF MARYLAND $50,000 Trans-NIH Recovery Act Research Support Diabetes Research and Training Center This application is in response to the National Institutes of Health Notice NOT-OD-09-056 (administrative supplement for Research Center Grants). The Baltimore DRTC requests supplemental funding of programs that will
This spending item is part of a $277,045 allocation. See details
National Institutes of Health 9/21/2009
CARNEGIE INSTITUTION OF WASHINGTON $49,527 Trans-NIH Recovery Act Research Support The award was a Supplement to the NIH Parent Grant 5RO1HD042215-07, Left-Right Asymmetry of the Developing Diencephalon under NOT-OD-09-060 to Principal Investigator Dr. Marnie Halpern. The funds are being used to purchase an Olympus MVX10 MacroScope wi National Institutes of Health 7/07/2010
FRIENDS RESEARCH INSTITUTE, INC $49,212 Trans-NIH Recovery Act Research Support UCLA AIDS PREVENTION AND TREATMENT CLINICAL TRIALS UNIT The UCLA AIDS Prevention and Treatment Clinical Trials Unit (UCLA-APT-CTU) is a multidisciplinary research unit composed of a core administrative unit and four clinical research sites in metropolitan
This spending item is part of a $1,970,379 allocation. See details
National Institutes of Health 9/21/2009
JOHNS HOPKINS UNIVERSITY, THE $49,200 Trans-NIH Recovery Act Research Support The overall goal in this program project is to understand the potential of ligands of the human immunodeficiency virus (HIV-1) gp120 envelope glycoprotein to inhibit virus entry. This Administrative supplement is submitted in response to NOT-OD-09-056: N
This spending item is part of a $519,761 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $49,198 Trans-NIH Recovery Act Research Support Antibiotic resistance is an increasing public health problem that is associated with considerable morbidity, mortality and costs. Given the reduced pace of antibiotic discovery and the approaching demographic shift towards an increasingly aged population, National Institutes of Health 8/02/2010
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $49,105 ARRA - Immunization The goal for the use of these funds is to increase the number of children and adults vaccinated against vaccine-preventable diseases. Grant funds will be allocated in the following manner: School-Age Influenza Campaign: $1,500.000 LHD Special Projects:
This spending item is part of a $1,945,219 allocation. See details
Centers for Disease Control and Prevention 9/15/2009
JOHNS HOPKINS UNIVERSITY, THE $48,339 Trans-NIH Recovery Act Research Support Since the passage of landmark welfare reform legislation in 1996, considerable attention has been paid to the impact of the time-limited benefits, sanctions, and work requirements of the law, as well as its overall impact, on economic and demographic outc National Institutes of Health 9/28/2009
UNIVERSITY OF MARYLAND $47,775 Trans-NIH Recovery Act Research Support Bioterrorism is no longer a threat in the United States, but a reality. In 2001, the spread of anthrax spores through the U.S. mail illustrated that deadly agents can be acquired and spread using relatively unsophisticated means. It also highlighted our v National Institutes of Health 8/23/2010
JOHNS HOPKINS UNIVERSITY, THE $47,352 Trans-NIH Recovery Act Research Support The Studies of the Ocular Complications of AIDS Research Group is dedicated to understanding and improving the outcomes of the ocular complications of AIDS. The Longitudinal Study of the Ocular Complications of AIDS (LSOCA) is a prospective cohort study o
This spending item is part of a $433,381 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF MARYLAND $47,019 Trans-NIH Recovery Act Research Support DNA and RNA exhibit an amazing degree of conformational polymorphism that is essential for their wide variety of biological functions, including replication and gene regulation. The importance of this polymorphism in the biological functions of oligonucle National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $45,900 Trans-NIH Recovery Act Research Support Community Partnerships for Child Safety: This project aims to prevent Injuries to Children in Baltimore City by building on ongoing community work: a) Johns Hopkins CARES (Children ARE Safe) mobile resource center; b) Baltimore City Fire Department neighb National Institutes of Health 6/24/2009
JOHNS HOPKINS UNIVERSITY, THE $45,900 Trans-NIH Recovery Act Research Support Community Partnerships for Child Safety: This project aims to prevent Injuries to Children in Baltimore City by building on ongoing community work: a) Johns Hopkins CARES (Children ARE Safe) mobile resource center; b) Baltimore City Fire Department neighb National Institutes of Health 5/03/2010
UNIVERSITY OF MARYLAND $45,000 Trans-NIH Recovery Act Research Support The purpose of this award to perform research on streptococci and streptococcal diseases in order to better understand the underlying molecular processes, eventually leading to better design of preventative and therapeutic strategies. Group A streptococc
This spending item is part of a $394,800 allocation. See details
National Institutes of Health 8/01/2009
JOHNS HOPKINS UNIVERSITY, THE $44,682 Trans-NIH Recovery Act Research Support Alzheimer's disease is characterized by the aggregation of 13-amyloid (A13) protein in the brain, widespread neurodegeration, and cognitive decline. Our work focuses on amelioration of Alzheimer's pathology by reducing or simplifying the major brain gang
This spending item is part of a $945,128 allocation. See details
National Institutes of Health 9/04/2009
UNIVERSITY OF MARYLAND $44,560 Trans-NIH Recovery Act Research Support The transcriptional activator TonEBP is essential for the development and function of the renal medulla. Activated by hypertonicity (hyperosmotic salinity), TonEBP is a key regulator for the urinary concentration via stimulating transcription of aquaporin National Institutes of Health 8/29/2009
BALTIMORE SUBSTANCE ABUSE SYSTEMS, INC $44,550 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (05): Comparative Effectiveness Research, and specific Challenge Topic (05-DA-104): Comparing Drug Treatment Effectiveness in Ethnic Minority Populations Background: Although there is relatively little diffe
This spending item is part of a $990,091 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $44,080 Trans-NIH Recovery Act Research Support G?? This is the final report for this award. The project is complete and all awarded funds have been exhausted. National Institutes of Health 9/14/2009
UNIVERSITY OF MARYLAND $44,046 Trans-NIH Recovery Act Research Support Success of corneal transplant is dependent on high corneal endothelial (CE) cell density maintained immediately after surgery and thereafter. CE cells die either by acute necrosis, which initiates detrimental inflammatory responses, or by a slow programme National Institutes of Health 7/22/2009
UNIVERSITY OF MARYLAND $43,200 Trans-NIH Recovery Act Research Support Globalization of research activities occurs in a very heterogeneous world, because developing countries differ from industrialized countries regarding economic, social, and cultural contexts. Such differences bring up the concern with exploitation and inc National Institutes of Health 9/03/2009
JOHNS HOPKINS UNIVERSITY, THE $43,200 Trans-NIH Recovery Act Research Support Johns Hopkins-Fogarty African Bioethics Training Program (FABTP) Collaborative Website. This ARRA award is a supplement to an existing R25 Fogarty International Center (FIC) training grant provided to the Johns Hopkins-Fogarty African Bioethics Training P National Institutes of Health 9/03/2009
JOHNS HOPKINS UNIVERSITY, THE $42,707 Trans-NIH Recovery Act Research Support The funds from this supplement will be used to hire an additional technician. The tech will assist with maternal behavior and feeding behavior experiments to increase the tempo of our research within the scope of the parent grant and shorten the time requ National Institutes of Health 9/29/2009
PENNIMAN & BROWNE, INC. $42,610 Construction Manager as Constructor at Risk services to renovation Building 10, F Wing in two phases: Phase A of the F Wing Renovation: Pre construction, construction, activation/occupancy and closeout; to convert 64,000 gsf of former patient care units o
This spending item is part of a $131,640,100 allocation. See details
National Institutes of Health 7/30/2010
JOHNS HOPKINS UNIVERSITY, THE $41,114 Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation. See details
National Institutes of Health 9/14/2009
JOHNS HOPKINS UNIVERSITY, THE $41,000 Trans-NIH Recovery Act Research Support The human cutaneous circulation is an accessible, representative vascular bed for in vivo examination of mechanisms that contribute to vascular dysfunction with essential hypertension (HT). This proposal is a logical extension of our previous work investi
This spending item is part of a $765,515 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF MARYLAND $40,000 Trans-NIH Recovery Act Research Support Diabetes mellitus in pregnancy is one of the maternal diseases that cause congenital defects in infants. Although control of glycemic level during pregnancy has been associated with reduced rate of malformed infants, nevertheless, achieving and maintainin National Institutes of Health 12/21/2009
UNIVERSITY OF MARYLAND $40,000 Trans-NIH Recovery Act Research Support Ectopic fat deposition, which is the accumulation of lipid droplets outside the adipose tissue, is well recognized as a strong prognostic factor for the development of insulin resistance and 'metabolic syndrome' in obesity and people with lipodystrophies. National Institutes of Health 12/21/2009
JOHNS HOPKINS UNIVERSITY, THE $39,950 Trans-NIH Recovery Act Research Support The latent reservoir for HIV-1 in resting CD4+ T cells is a major barrier to virus eradication. There is great current interest in developing strategies for eliminating this reservoir. This will require a more complete understanding of the molecular mecha National Institutes of Health 7/14/2009
JOHNS HOPKINS UNIVERSITY, THE $39,865 Trans-NIH Recovery Act Research Support ARRA Supplement to Environmental Exposure to Metal Mixtures and Kidney Disease PROJECT SUMMARY Humans are exposed to chemical mixtures in all environmental media, yet environmental policies rest primarily on studies of single chemical exposures. Secondary National Institutes of Health 9/06/2009
UNIVERSITY OF MARYLAND $39,616 Trans-NIH Recovery Act Research Support Dual-diagnosis in psychiatry refers to the co-existence of drug abuse with a psychiatric condition. This is quite prevalent in schizophrenia, where more than 50% of the patients abuse some type of drug. There is no agreement in the field regarding whether
This spending item is part of a $55,008 allocation. See details
National Institutes of Health 6/19/2009
UNIVERSITY OF MARYLAND $38,076 Trans-NIH Recovery Act Research Support Identification of Genes Causing Familial Crohn?s Disease. Nearly 500,000 Americans, both children and adults, have Crohn?s disease, and in approximately one-quarter of those affected, two or more family members have the disease. People of Jewish ancestry
This spending item is part of a $1,640,420 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $38,048 Trans-NIH Recovery Act Research Support The focus of our current studies has been to determine the role of transcription factor IRF-5 in the antiviral and inflammatory responses to virus infection and TLR ligands. To this effect we have analyzed IFN and cytokine levels in Irf5-/- mice and obser National Institutes of Health 7/15/2009
JOHNS HOPKINS UNIVERSITY, THE $38,042 Trans-NIH Recovery Act Research Support This award was an administrative supplement in support of An Open-Source Algorithm Isolating Overlapping Signatures in Microarray Data. The primary request of this supplement was for funds to provide for the purchase of high-powered computational nodes de National Institutes of Health 9/17/2009
UNIVERSITY OF MARYLAND $37,680 Trans-NIH Recovery Act Research Support There are persistent questions regarding the evolution and function of the immune system. Previously studies performed in non-mammalian vertebrates have helped to reveal basic features of the immune system that are universal. In other cases, studies outsi National Institutes of Health 8/22/2009
CARNEGIE INSTITUTION OF WASHINGTON $37,253 Trans-NIH Recovery Act Research Support The Award was a Summer Supplement to the NIH Parent Grant 2RO1HD042215-06, Left-Right Asymmetry of the Developing Diecephalon under direction of Dr. Marnie Halpern National Institutes of Health 6/02/2009
JOHNS HOPKINS UNIVERSITY, THE $37,166 Trans-NIH Recovery Act Research Support The significance of a sound is encoded not only in the firing patterns distributed throughout the auditory system, but also by the internal and external state of the animal. In other words, the processing involves not only the auditory system but also neu National Institutes of Health 5/28/2009
JOHNS HOPKINS UNIVERSITY, THE $36,416 Trans-NIH Recovery Act Research Support The National Survey of Adolescent Males (NSAM) Center for Adolescent Health, Johns Hopkins Bloomberg School of Public Health. The main impetus of the original (parent) grant, NSAM: Wave 4: HIV/STD Risk Trajectories is to gain a more comprehensive and deve National Institutes of Health 7/13/2009
JOHNS HOPKINS UNIVERSITY, THE $36,416 Trans-NIH Recovery Act Research Support The main impetus of the original (parent) grant, NSAM: Wave 4: HIV/STD Risk Trajectories is to gain a more comprehensive and developmental understanding of HIV/STD risk behaviors among a nationally representative sample of males, who range in age from 32 National Institutes of Health 5/06/2010
JOHNS HOPKINS UNIVERSITY, THE $35,630 Trans-NIH Recovery Act Research Support This NIH Challenge Grant application addresses the specific Challenge Area (05): Comparative Effectiveness Research, and the specific Challenge Topic, 05-CA-104: Comparative Effectiveness Research in Cancer Treatment. This study will examine patterns of t
This spending item is part of a $773,678 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $35,326 Trans-NIH Recovery Act Research Support This award supports the therapeutic work for childhood Acute Lymphoblastic Leukemia (ALL), which is the most common childhood cancer and is a leading cause of cancer-related death. This project is designed to 1) validate the key TARGET (Therapeutically A
This spending item is part of a $1,708,950 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $35,129 Trans-NIH Recovery Act Research Support This NIH Challenge Grant application addresses the specific Challenge Area (05): Comparative Effectiveness Research, and the specific Challenge Topic, 05-CA-104: Comparative Effectiveness Research in Cancer Treatment. This study will examine patterns of t
This spending item is part of a $773,678 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $34,989 Trans-NIH Recovery Act Research Support We convene our investigators, sub-contractors and staff for weekly meetings focused on data quality, analysis and curriculum development.. Project staff and PIs have additional weekly meetings. ICF Macro is nearing completion of in-depth interviews and te
This spending item is part of a $2,355,935 allocation. See details
National Institutes of Health 9/27/2010
JOHNS HOPKINS UNIVERSITY, THE $34,980 Trans-NIH Recovery Act Research Support The hypothalamus plays a central role in maintaining energy homeostasis. Within the hypothalamus, different nuclei have been shown to play distinct roles in controlling food intake and energy expenditure. Although a role for the dorsomedial hypothalamus ( National Institutes of Health 2/26/2010
JOHNS HOPKINS UNIVERSITY, THE $33,690 Trans-NIH Recovery Act Research Support The Study to Help the AIDS Research Effort (SHARE) was funded by NIAID and NCI in 1983 to study the natural history of infection with human immunodeficiency virus, type 1 (HIV). SHARE, along with similar sites in Chicago, Pittsburgh, and Los Angeles, form National Institutes of Health 3/15/2010
JOHNS HOPKINS UNIVERSITY, THE $33,369 Trans-NIH Recovery Act Research Support This award supports the therapeutic work for childhood Acute Lymphoblastic Leukemia (ALL), which is the most common childhood cancer and is a leading cause of cancer-related death. This project is designed to 1) validate the key TARGET (Therapeutically A
This spending item is part of a $1,708,950 allocation. See details
National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $32,964 Trans-NIH Recovery Act Research Support The long term goal of this project is to develop new technology that will allow rapid user- defined patterning of proteins on cell culture substrates at dimensions ranging from 50 nanometers to millimeters. Patterned cell culture substrates are emerging a
This spending item is part of a $96,755 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $32,800 Trans-NIH Recovery Act Research Support The goal of this proposal is to elucidate the pathway of programmed cell death by a novel antifungal agent and explore its use as an antimycotic adjunct. Amiodarone is an effective antiarrhythmic drug that was recently discovered to have potent and broad National Institutes of Health 7/14/2009
JOHNS HOPKINS UNIVERSITY, THE $32,472 Trans-NIH Recovery Act Research Support ?Maturation functions of the HSV-1 tegument?. Herpes simplex virus (HSV) assembles an icosahedral capsid and packages this structure with the viral genome in the nucleus. It then has to exit the nucleus using a complex envelopment/de-envelopment pathway t National Institutes of Health 5/24/2010
JOHNS HOPKINS UNIVERSITY, THE $30,386 Trans-NIH Recovery Act Research Support The funds requested will be used to purchase a Tecan Infinite M200 Fluorescence plate reader with shaking platform and temperature control. This highly versatile instrument will enhance our abilities to fulfill all three aims of our current NIH R01 grant National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $30,096 Trans-NIH Recovery Act Research Support The goal of this award is to introduce students to scientific research experiences and to stimulate the economy by providing summer employment opportunities to college students. National Institutes of Health 7/16/2009
UNIVERSITY OF MARYLAND $30,000 Trans-NIH Recovery Act Research Support Diabetes Research and Training Center This application is in response to the National Institutes of Health Notice NOT-OD-09-056 (administrative supplement for Research Center Grants). The Baltimore DRTC requests supplemental funding of programs that will
This spending item is part of a $277,045 allocation. See details
National Institutes of Health 9/21/2009
PARAGON BIOSERVICES, INC. $29,700 Transient VLP Expression in 293T Cells and Purification. National Institutes of Health 9/10/2010
JOHNS HOPKINS UNIVERSITY, THE $29,376 To establish a coordinated process structured to meet previously-identified scientific needs for quantitative imaging biomarkers. The long-term objective is to establish processes and profiles that will lead to acceptance by the imaging community, clinica
This spending item is part of a $2,412,566 allocation. See details
National Institutes of Health 9/30/2010
JOHNS HOPKINS UNIVERSITY, THE $29,329 Trans-NIH Recovery Act Research Support This was an administrative supplement to Project 2 of the PO1 entitled Bone Marrow Transplantation in Human Disease. Work by Borrello and colleagues recently focused on increasing the overall efficacy of adoptive T cell therapy. Specifically, the initial National Institutes of Health 8/28/2009
JOHNS HOPKINS UNIVERSITY, THE $27,962 Trans-NIH Recovery Act Research Support Summer Educator Award. This administrative supplement request focuses on the regulation of virulence factors by intracellular NAD+ concentration. We have shown that virulence associated adhesin genes are transcriptionally induced in response to low enviro National Institutes of Health 7/21/2009
JOHNS HOPKINS UNIVERSITY, THE $27,640 Trans-NIH Recovery Act Research Support Supplemental request for funds to purchase equipment (an environmental chamber) and to pay for user fees on the new state-of-the-art two-photon microscope in the Johns Hopkins University School of Medicine?s core imaging facility. These purchases will gre National Institutes of Health 9/28/2009
AGING, MARYLAND DEPARTMENT OF $27,338 Aging Home-Delivered Nutrition Services for States ARRA provided funding for home delivered meal services. Established in 1972 under the Older American Act, the program provides meals for older americans in their homes.
This spending item is part of a $546,714 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF MARYLAND $27,000 Trans-NIH Recovery Act Research Support This is a revised U56 application to the National Cancer Institute to support the planning and development of a Comprehensive Minority Institution and Cancer Center Partnership between the University of Maryland Eastern Shore (UMES--a minority serving ins National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $27,000 Trans-NIH Recovery Act Research Support The Gly380?Arg mutation in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) is linked to achondroplasia, the most common form of human dwarfism in more than 97% of all studied cases. We are seeking the physical basis behind the diso National Institutes of Health 9/30/2009
UNIVERSITY OF MARYLAND $25,995 Trans-NIH Recovery Act Research Support The overall goal of the parent grant is to develop accurate methods for computing noncovalent binding affinities and thereby speed the discovery of new medications and targeted molecules for other biomedical applications.-? This Administrative Supplement
This spending item is part of a $39,620 allocation. See details
National Institutes of Health 6/18/2010
JOHNS HOPKINS UNIVERSITY, THE $25,978 Trans-NIH Recovery Act Research Support Resemblance Between Child & Parental Eating, Physical Activity & Obesity Patterns: The ARRA award is a supplemental grant to help support additional research, mainly analysis of additional data than what we proposed in the original parent project supporte National Institutes of Health 9/29/2009
JOHNS HOPKINS UNIVERSITY, THE $25,543 Trans-NIH Recovery Act Research Support Polyploidy resulting from the fertilization of an egg by more than one sperm will be fatal to an embryo. Fertilization of an egg by two sperm will results in a triploid embryo. Triploidy is detected in ~10% of spontaneous abortions and the majority of tri National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $25,346 Trans-NIH Recovery Act Research Support This study examines 1800 patients treated at more than 20 centers with expertise in robotic and standard prostate surgery; the patients have been evaluated for quality of life before and after surgery, and for complications, costs, and cancer control. WeG
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/22/2009
JOHNS HOPKINS UNIVERSITY, THE $25,000 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) and its metabolic derangements substantially affect the well-being of children. In order to define the nature, magnitude, and temporal evolution of the adverse effects of progressive CKD, we propose to extend the follow-up of
This spending item is part of a $329,400 allocation. See details
National Institutes of Health 6/11/2010
JOHNS HOPKINS UNIVERSITY, THE $24,534 Trans-NIH Recovery Act Research Support Title of the main project is ?Role of Fra-1 in acute lung injury and repair.? The ARRA funding is to provide support to a summer student training. Acute lung injury (ALI) or its most severe form acute respiratory distress syndrome (ARDS), caused by exposu National Institutes of Health 7/11/2009
JOHNS HOPKINS UNIVERSITY, THE $21,641 Trans-NIH Recovery Act Research Support Summer undergraduate research experience in studies engineering a carbohydrate-biomaterial interface for control of Wnt signaling National Institutes of Health 6/16/2009
JOHNS HOPKINS UNIVERSITY, THE $21,641 Trans-NIH Recovery Act Research Support Summer undergraduate research experience in the design and study of monosaccharide analogs, sialic acid metabolism, and apoptosis National Institutes of Health 6/01/2009
JOHNS HOPKINS UNIVERSITY, THE $20,930 Trans-NIH Recovery Act Research Support This supplement will allow the purchase of additional food intake monitoring cages for rats, to facilitate the aims of the project. National Institutes of Health 12/09/2009
ENVIRONMENTAL & DEMOLITION SERVICES, INC. $20,104 The F Wing Decommissioning project requires the decommissioning and demolition of Floors 6 thru 14 of Building 10, F Wing. This decommissioning and demolition consists of an abatement survey of the spaces, the abatement of the spaces to be demolished, ab
This spending item is part of a $2,507,720 allocation. See details
National Institutes of Health 4/05/2010
JOHNS HOPKINS UNIVERSITY, THE $20,000 Trans-NIH Recovery Act Research Support Nanotechnology, the use of nanomaterials at the molecular level, is a multidisciplinary scientific field undergoing exponential growth and has broad applications among all divisions of science. One form of nanomaterials, fullerenes, are soc
This spending item is part of a $555,726 allocation. See details
National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $17,004 Trans-NIH Recovery Act Research Support Support of undergraduate education and training in translational research National Institutes of Health 5/29/2009
JOHNS HOPKINS UNIVERSITY, THE $16,400 Trans-NIH Recovery Act Research Support This supplement supported the hiring of two undergraduate students for the summer. Both students contributed to the progress of the project by processing brain tissue of rats that had undergone multi-day peripheral injections of gut peptides or multi-day National Institutes of Health 7/14/2009
JOHNS HOPKINS UNIVERSITY, THE $16,400 Trans-NIH Recovery Act Research Support Since the original budget period this application, the PI has offered summer college students an opportunity to work on projects related to the renal physiological questions proposed in the grant proposal. This gives the students the opportunity to learn National Institutes of Health 8/14/2009
JOHNS HOPKINS UNIVERSITY, THE $15,820 Trans-NIH Recovery Act Research Support This stage one TRIP application will enable a phase II clinical trial of a new therapy to treat sickle cell disease (SCD) in two years. The basis of our proposal is our recent discovery that invariant NKT (iNKT) cells contribute importantly to tissue infl
This spending item is part of a $1,817,442 allocation. See details
National Institutes of Health 9/28/2009
JOHNS HOPKINS UNIVERSITY, THE $15,265 Trans-NIH Recovery Act Research Support Summer undergraduate research experience in studies of cardiac electrophysiology and arrhythmia using an in vitro model National Institutes of Health 6/04/2009
JOHNS HOPKINS UNIVERSITY, THE $13,601 Trans-NIH Recovery Act Research Support This effort requires the development of new therapies that target the provirus residing within infected cells in a status of non-productive infection. Advances toward that goal will require a quantum leap in our knowledge and understanding of the biology
This spending item is part of a $421,129 allocation. See details
National Institutes of Health 7/17/2009
UNIVERSITY OF MARYLAND $13,075 Trans-NIH Recovery Act Research Support The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an
This spending item is part of a $1,701,287 allocation. See details
National Institutes of Health 11/25/2009
JOHNS HOPKINS UNIVERSITY, THE $12,547 Trans-NIH Recovery Act Research Support Activity #1 - summer intern -03S1: The goal of the summer project was to simulate and visually demonstrate impingement during the planning phase of the hip osteotomy procedure, include the interface as a simulation constraint when optimizing (minimizing) National Institutes of Health 5/28/2009
JOHNS HOPKINS UNIVERSITY, THE $12,500 Trans-NIH Recovery Act Research Support The CellsZcope is an automated instrument that allows for a more reliable monitoring of electrical integrity of cellular monolayers in real time. In addition, the paracellular permeability to solutes, another measure of integrity of brain endothelial mono National Institutes of Health 7/15/2009
JOHNS HOPKINS UNIVERSITY, THE $11,675 Trans-NIH Recovery Act Research Support Asthma is the most common chronic disease of childhood, and it disproportionately affects urban, minority, and disadvantaged children. When implemented correctly, existing evidence-based guidelines from the National Heart, Lung, and Blood Institute (NHLBI
This spending item is part of a $196,721 allocation. See details
National Institutes of Health 9/24/2009
JOHNS HOPKINS UNIVERSITY, THE $10,704 Trans-NIH Recovery Act Research Support There were two supplements for this award. The first was to support the addition of an undergraduate student during the past summer. The student was hired and worked effectively on this program. The student's work focused on processing brains from develop National Institutes of Health 7/29/2009
JOHNS HOPKINS UNIVERSITY, THE $10,616 Trans-NIH Recovery Act Research Support This supplement is for 5R03HD055216-02, ?Mothers' attitudes about elective cesarean: results, expectations & satisfaction? (MADRES).-? The original goals of the MADRES study were to study the attitudes and expectations of pregnant women with respect to ch National Institutes of Health 5/27/2009
JOHNS HOPKINS UNIVERSITY, THE $10,168 Trans-NIH Recovery Act Research Support Neurotrophins affect airway smooth muscle tone. Air flows into the lungs through the conducting airways (trachea and bronchi) and, with every breath we take, the airways rhythmically contract and relax with each breath; this change in airway smooth muscle National Institutes of Health 6/05/2009
JOHNS HOPKINS UNIVERSITY, THE $9,512 Trans-NIH Recovery Act Research Support This project exposed an undergraduate student to basic science research. The student wored under the direct supervision of a senior Research Associate in the Department. He carried out a project comparing available antibodies to the four rodent and two hu National Institutes of Health 6/05/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $9,166 ARRA - Immunization The Maryland Emerging Infections Program (EIP) will use these funds to support the G?13-valent Pneumococcal Conjugate Vaccine Effectiveness Study (PCV13)G?. The PCV13 project is a case-control study designed to evaluate the effectiveness of the 13-valent Centers for Disease Control and Prevention 4/22/2010
JOHNS HOPKINS UNIVERSITY, THE $8,528 Trans-NIH Recovery Act Research Support ARRA Summer Research Experience: Student National Institutes of Health 7/21/2009
JOHNS HOPKINS UNIVERSITY, THE $8,528 Trans-NIH Recovery Act Research Support ARRA Summer Research Experience: StudentParent Project-50NS038377, The Morris K Udall Parkinson's Disease Research Center for Excellence, Project 3: LRRK2 Biology in PD. National Institutes of Health 7/15/2009
JOHNS HOPKINS UNIVERSITY, THE $8,399 Trans-NIH Recovery Act Research Support This effort requires the development of new therapies that target the provirus residing within infected cells in a status of non-productive infection. Advances toward that goal will require a quantum leap in our knowledge and understanding of the biology
This spending item is part of a $421,129 allocation. See details
National Institutes of Health 7/17/2009
JOHNS HOPKINS UNIVERSITY, THE $8,200 Trans-NIH Recovery Act Research Support This project explores how a gene family of multi-PDZ domain proteins called the NHERF family which are located in the apical domain of epithelial cells takes part in regulation of intestinal Na absorption by affecting the brush border Na/H antiporter NHE3 National Institutes of Health 7/13/2009
JOHNS HOPKINS UNIVERSITY, THE $8,200 Trans-NIH Recovery Act Research Support There were two supplements for this award. The first was to support the addition of an undergraduate student during the past summer. The student was hired and worked effectively on this program. The student's work focused on processing brains from develop National Institutes of Health 7/30/2009
JOHNS HOPKINS UNIVERSITY, THE $8,200 Trans-NIH Recovery Act Research Support Since the original budget period this application, the PI has offered summer college students an opportunity to work on projects related to the physiological questions proposed in the grant proposal. This gives the students the opportunity to learn labora National Institutes of Health 6/05/2009
JOHNS HOPKINS UNIVERSITY, THE $8,200 Trans-NIH Recovery Act Research Support This project aims to understand how proteins which associate with the NHES C-terminus between aa 590-685 regulate NHE3. The proteins identified which bind NHES in the domain and are involved in its regulation under basal conditions include CK2, CaM KII, N National Institutes of Health 7/16/2009
D R LYNES $8,000 Trans-NIH Recovery Act Research Support The University of Maryland Baltimore is submitting this application to establish a Bioethics Center under the NCMHD ARRA Scientific priority area 'Bioethics Research Infrastructure Initiative' through 'GO' grants RFA-OD-09-004. This Bioethics Center's pro
This spending item is part of a $2,425,363 allocation. See details
National Institutes of Health 9/27/2009
JOHNS HOPKINS UNIVERSITY, THE $7,457 Trans-NIH Recovery Act Research Support The ARRA funds I received were under call NOT-OD-09-60 Administrative Supplement Providing Summer Research Experiences for Students and Science Educators, to supplement my NIH R21 grant 1R21AI077907-01A1 from the NATIONAL INSTITUTE OF ALLERGY AND INFECTIO National Institutes of Health 6/05/2009
JOHNS HOPKINS UNIVERSITY, THE $6,396 Trans-NIH Recovery Act Research Support The Summer Research Experience for Students and Educators award funded 2.5 undergraduates to work on a larger 5-year project investigating the development of numerical cognition. This parent project aims to characterize the foundational Approximate Number National Institutes of Health 7/15/2009
ENVIRONMENTAL & DEMOLITION SERVICES, INC. $4,951 Construction of the NIH Porter Neuroscience Research Center Phase II. The project is approximately 300,000 GSF.
This spending item is part of a $157,030,324 allocation. See details
National Institutes of Health 5/13/2010
JOHNS HOPKINS UNIVERSITY, THE $3,280 Trans-NIH Recovery Act Research Support A part-time undergraduate student that is from an underrepresented population in science (African-American) was hired for work on this project. Her efforts focused on immunohistochemical detection of specific proteins in the hypothalamus that may play a r National Institutes of Health 7/13/2009
JOHNS HOPKINS UNIVERSITY, THE $0 Trans-NIH Recovery Act Research Support This grant proposal focuses our sustained laboratory and clinical research experience in animal and human stem cell biology and leukemia to extend exciting new investigations on normal tissue-specific and cancer stem cells. The investigators in this PPG l
This spending item is part of a $200,002 allocation. See details
National Institutes of Health 9/07/2009
UNIVERSITY OF MARYLAND $0 Trans-NIH Recovery Act Research Support Each year, novel strains of influenza A virus arise through mutation and manage to infect one-fifth of the human population. We remain woefully ignorant of what specific features determine the success or failure of these antigenic drift variants. As a res
This spending item is part of a $669,831 allocation. See details
National Institutes of Health 9/21/2009
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $0 ARRA - State Loan Repayment Program SLRP is a collaborative effort among state and federal entities that offers physicians an opportunity to practice their profession in a community that lacks adequate primary
This spending item is part of a $200,000 allocation. See details
Health Resources and Services Administration 9/16/2009
BALTIMORE, CITY OF $0 ARRA Health Center Integrated Services Development Initiative[g1] The Capital Improvement Project was intended to provide equipment and connectivity which would have allowed the funded health center staff access to the City's computer network to allow for e-mail and the implementation of an electroni... Show more Health Resources and Services Administration 6/25/2009
JOHNS HOPKINS BAYVIEW MEDICAL CENTER, INC $0 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We request funds to develop a Translational Molecular Imaging Center (TMIC) on the Johns Hopkins Bayview (JHB) medical campus. There is currently no such center at the Johns Hopkins Medical Institutions (JHMI) and few,
This spending item is part of a $7,000,028 allocation. See details
National Institutes of Health 3/31/2010
HEALTH & MENTAL HYGIENE, MARYLAND DEPARTMENT OF $0 ARRA - State Grants to Promote Health Information Technology The purpose of the State Health Information Exchange Cooperative Agreement Program is to fund states' efforts to rapidly build capacity for exchanging health information across the health care system both within and across states. Awardees... Show more
This spending item is part of a $10,997,095 allocation. See details
Health and Human Services, Department of 3/15/2010