Dallas County, Texas, funds by Health and Human Services, Department of

Listing $179,414,693.56 in stimulus funds from Health and Human Services, Department of for Dallas

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient	Amount	Description	Federal Dept./Agency	Date
TRAILBLAZER HEALTH ENTERPRISES LLC	$22,359,231	HITECH Business Operations Support Contract (HBOSC). This ARRA funded initiative is designed to provide support to the HITECH Electronic Health Record Incentive Payment Program. The goal of this task area is : ? Provide assistance to the medical provide This spending item is part of a $26,687,621 allocation. See details	Health Care Financing Admin. (was Medicare and Medicaid Serv.)	9/14/2010
DALLAS COUNTY LOCAL WORKFORCE DEVELOPMENT BOARD, INC.	$16,052,911	ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care. This spending item is part of a $214,851,599 allocation. See details	Administration for Children and Families	4/09/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$14,954,444	National Center for Research Resources, Recovery Act Construction Support This is a request for $14,954,444 million dollars in renovation funds to complete 63,397 square feet of shell space in a newly constructed biomedical research building. The project will complete three floors of what is currentltly termed the Phase V researc... Show more See details	National Institutes of Health	3/04/2010
DALLAS COUNTY LOCAL WORKFORCE DEVELOPMENT BOARD, INC.	$4,879,971	ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care. This spending item is part of a $214,851,599 allocation. See details	Administration for Children and Families	4/09/2009
URBAN LEAGUE OF GREATER DALLAS AND NORTH CENTRAL TEXAS, INC. THE	$4,285,529	ARRA - Community Services Block Grant The CSBG ARRA award is Recovery Act funding for the Community Services Block Grant. The purpose of the program is to provide supplemental funds for job preservation, infrastructure investment, energy efficiency and science, assistance to the unemployed a This spending item is part of a $48,148,071 allocation. See details	Administration for Children and Families	4/10/2009
HEAD START OF GREATER DALLAS INC	$3,902,880	ARRA - Early Head Start Grant was awarded to expand Early Head Start services to 144 infants, toddlers and pregnant women. The service area is Mesquite, Jubilee, and Galand/Richardson, TX and includes startup costs, prorated costs for operations, and training and technical assis See details	Administration for Children and Families	11/18/2009
DALLAS-FORT WORTH HOSPITAL COUNCIL EDUCATION AND RESEARCH FOUNDATION	$3,891,018	ARRA - Health Information Technology Extension Program This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance, and information on best practices to support and accelerate health care providers? effoforts to be... Show more This spending item is part of a $9,418,318 allocation. See details	Health and Human Services, Department of	4/06/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$3,750,000	Trans-NIH Recovery Act Research Support The purpose of this project is to discover new therapeutic targets and drug leads for treating lung cancer. To do this, we have completed an analysis of 56 lung cancer cell lines and have assigned them to 6 genetically distinct clades. Two representativ See details	National Institutes of Health	9/29/2009
BAYLOR RESEARCH INSTITUTE, THE	$3,495,192	Trans-NIH Recovery Act Research Support Vaccines represent the major success of immunology and have spared countless numbers of people from infections. Despite this success, we understand little about how effective vaccines stimulate protective immune responses. We surmise that understanding th This spending item is part of a $4,499,507 allocation. See details	National Institutes of Health	7/12/2010
NEIGHBORS UNITED FOR QUALITY EDUCATION INC	$3,079,574	ARRA - Early Head Start Early Head Start (ARRA) - This award provides the opening of a new Early Head Start program in a very low income area of Dallas. The ARRA Early Head Start Expansion is funded to serve 140 children. The Early Head Start program provides family-centered s See details	Administration for Children and Families	4/21/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$2,180,828	Trans-NIH Recovery Act Research Support Genome-wide association scans (GWAS) in human SLE have identified DNA segments that likely harbor causal variants, however, the precise identities of these variants have remained elusive. The primary objective of this 'Grand Opportunity' proposal is to d This spending item is part of a $4,299,997 allocation. See details	National Institutes of Health	9/29/2009
Wavetwo, LLC	$2,000,000	ARRA - Health Information Technology Extension Program This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance, and information on best practices to support and accelerate health care providers? effoforts to be... Show more This spending item is part of a $9,418,318 allocation. See details	Health and Human Services, Department of	4/06/2010
BAYLOR RESEARCH INSTITUTE, THE	$1,972,965	Trans-NIH Recovery Act Research Support Vaccination represents one of the major successes of medicine as it has spared countless people from polio, tetanus and other acute infections. Yet, improved immunization strategies are needed to make vaccines for microbes that cause considerable morbidit This spending item is part of a $5,292,047 allocation. See details	National Institutes of Health	9/21/2009
HEAD START OF GREATER DALLAS INC	$1,949,549	ARRA - Head Start Grant was awarded to fund a temporary cost-of-living adjustment (COLA) increase for both Head Start and Early Head Start employees; provide quality improvement funds to improve compensation and qualifications/skills of educational personnel including thos This spending item is part of a $2,234,481 allocation. See details	Administration for Children and Families	6/29/2009
CHILDCAREGROUP	$1,775,711	ARRA - Early Head Start Early Head Start Expansion This program is a full-day, full-year, center and family child care based, Relationship-Centered Child Care option to meet the needs of families in which low-income parents are working, participating in training, or attending s See details	Administration for Children and Families	11/18/2009
DALLAS SERVICES	$1,745,369	ARRA - Early Head Start Early Head Start Expansion grant, funded via ARRA, to provide family centered services for low income families with very young children to promote the healthy development of children and families through an early childhood education/childcare services cen See details	Administration for Children and Families	4/12/2010
NORTH TEXAS ACCOUNTABLE HEALTHCARE PARTNERSHIP	$1,718,080	ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health h care system. Th... Show more This spending item is part of a $28,810,208 allocation. See details	Health and Human Services, Department of	3/15/2010
EDUCATION SERVICE CENTER REGION 10	$1,430,423	ARRA - Early Head Start Early Head Start Expansion - The Early Head Start program provides family-centered services for low income families with very young children (pre-birth to three) to promote the healthy development of the children and families. The program received fundin See details	Administration for Children and Families	11/18/2009
TEXAS A&M UNIVERSITY SYSTEM,THE	$1,363,946	Trans-NIH Recovery Act Research Support This proposed project, entitled 'Baylor's Program in Bioengineering Sciences and Translational Research (B-BEST)', will provide support for the hiring and development of two new faculty with expertise in Bioengineering Sciences and Translational Research. This spending item is part of a $1,375,946 allocation. See details	National Institutes of Health	9/17/2009
BAYLOR RESEARCH INSTITUTE, THE	$1,322,064	Trans-NIH Recovery Act Research Support Vaccination represents one of the major successes of medicine as it has spared countless people from polio, tetanus and other acute infections. Yet, improved immunization strategies are needed to make vaccines for microbes that cause considerable morbidit See details	National Institutes of Health	6/28/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,303,720	Trans-NIH Recovery Act Research Support 1. We purchased and received a mass spectrometer and have developed protocols for using it to sequence peptoids. 2. We successfully created an on-bead 5-mer peptoid library with individual library members composed of all combinations of ten possible mono See details	National Institutes of Health	9/29/2009
LOS BARRIOS UNIDOS COMMUNITY CLINIC, INC.	$1,300,000	ARRA Health Center Integrated Services Development Initiative[g1] ARRA: Recovery Act Health Center Cluster Program, New Access Point. The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underseserved area or for an ... Show more See details	Health Resources and Services Administration	3/03/2009
LOS BARRIOS UNIDOS COMMUNITY CLINIC, INC.	$1,300,000	ARRA Health Center Integrated Services Development Initiative[g1] ARRA: Recovery Act Health Center Cluster Program, New Access Point. The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underseserved area or for an ... Show more See details	Health Resources and Services Administration	3/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,287,252	Trans-NIH Recovery Act Research Support During the past quarter, we have made excellent progress in establishing Dr. Anwarul Ferdous as an independent investigator in the Division of Cardiology here at UT Southwestern Medical Center. He is swiftly establishing an independent program of researc See details	National Institutes of Health	9/28/2009
SCENPRO, INC.	$1,260,331	Provide support to the FDA for the conversion of legacy clinical trial data to the SDTM format and for the creation of analysis data sets to enable exploration of Comparative Effectiveness Research (CER) questions related to vaccines, drugs, and medical d This spending item is part of a $5,947,450 allocation. See details	Food and Drug Administration	9/15/2010
SCENPRO, INC.	$1,233,055	The Cancer Knowledge Cloud will connect and share information generated through NCI genomic atlas projects, the caHUB tissue acquisition network, the NCI functional Biology Consortium, NCI patient Characterization Center, the NCI pre-clinical Development This spending item is part of a $103,000,000 allocation. See details	National Institutes of Health	11/23/2009
DALLAS COUNTY COMMUNITY COLLEGE DISTRICT	$1,197,544	ARRA - Health Information Technology Professionals in Health Care Pitt Community College Region D Consortium - will seek to rapidly create HIT academic programs at Community Colleges or expand existing ones. Community Colleges are G?institutions of higher educationG? as defined by section 101 of the e Higher Education Act... Show more This spending item is part of a $20,817,547 allocation. See details	Health and Human Services, Department of	4/02/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,190,132	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): We are requesting an in vivo multiphoton microscope for the UT Southwestern Live Cell Imaging Facility (LCIF), a campus wide core facility that provides access to optical microscopy instrumentation for more than 150 re See details	National Institutes of Health	5/20/2010
SCENPRO, INC.	$1,185,000	CTRP Support: Architecture and Development: Provide Technical analysis and Architectural Support for the NCI Clinical Trial Reporting Program (CTRP). Development will focus on design and specifications needed for the CTRP interoperable NCI Enterprise Serv This spending item is part of a $6,700,000 allocation. See details	National Institutes of Health	11/23/2009
TRAILBLAZER HEALTH ENTERPRISES LLC	$1,128,300	MOD 54 J-4 Op Yr 3 for POP 01/20/2011 - 08/05/2011; to add SLIN 0005AJ RECOVERY - ARRA HITECH- Hospital initial payment program, and to (1) issue Change Order per Section 1.1, 52.243-2 Changes - Cost Reimbursement (Aug 1987), Alt 1 (Apr 1984) to incorpor See details	Health Care Financing Admin. (was Medicare and Medicaid Serv.)	8/06/2011
DALLAS, COUNTY OF	$1,099,480	ARRA - Immunization Grant funds to implement multiple projects that will result in a greater number of people, both children and adults, protected from vaccine-preventable diseases. Projects propose to increase capacity of the Department of State Health Service's field offic This spending item is part of a $6,495,738 allocation. See details	Centers for Disease Control and Prevention	9/15/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,087,420	Trans-NIH Recovery Act Research Support Elevations in the circulating level of C-reactive protein (CRP) are a strong predictor of the development of hypertension and insulin resistance. The proposed research program will determine how CRP and its cell surface receptors cause hypertension and in See details	National Institutes of Health	8/31/2009
SCENPRO, INC.	$1,004,295	The Cancer Knowledge Cloud will connect and share information generated through NCI genomic atlas projects, the caHUB tissue acquisition network, the NCI functional Biology Consortium, NCI patient Characterization Center, the NCI pre-clinical Development This spending item is part of a $103,000,000 allocation. See details	National Institutes of Health	11/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,000,000	Trans-NIH Recovery Act Research Support Glioblastoma is the most common primary brain tumor and is considered to be among the deadliest of human cancers. The metabolism of the cells is much higher than normal cells and, like many cancers, represents a possible target for new drugs in cancer the See details	National Institutes of Health	9/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$983,634	Trans-NIH Recovery Act Research Support This project is significant as it addresses scientific knowledge gaps in sophisticated quality of life and neurocognitive assessment tools, specifically the Neuro-QOL and the NIH Toolbox neurocognitive battery, through the use of a well-controlled psychom See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$982,032	Trans-NIH Recovery Act Research Support Autosomal recessive cystic kidney diseases are rare genetic disorders that produce kidney failure in children. No specific treatment currently exists. This proposal will test the feasibility of treating these disorders using a new technology, microRNA-bas See details	National Institutes of Health	9/22/2009
LOS BARRIOS UNIDOS COMMUNITY CLINIC, INC.	$981,920	ARRA Health Center Integrated Services Development Initiative[g1] AARA Capital Improvement Program: CIP funding will enhance efficiency and improve the qualiry of care and patient outcomes for Los Barrios Unidos Community Clinic (LBUCC) through two project types: 1) Alteration/Repair/Renovation andnd 2) Certified EHC-re... Show more See details	Health Resources and Services Administration	6/29/2009
Jhd Group, Inc.	$965,186	ARRA - Health Information Technology Extension Program USA'S CENTER FOR STRATEGIC HEALTH INNOVATION HAS FORMED A CONSORTIUM OF PARTNERS INCLUDING ALABAMA MEDICAID AGENCY, UNIVERSITY OF ALABAMA AT BIRMINGHAM, AUBURN UNIVERSITY AND THE ALABAMA PRIMARY HEALTHCARE ASSOCIATION TO SERVE AS THE ALABAMA REGIGIONAL EXTE... Show more This spending item is part of a $9,042,318 allocation. See details	Health and Human Services, Department of	4/06/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$949,060	Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15): Translational Science, and Specific Challenge Topic 15-NS-104: Early Stage Therapy Development. We propose to develop and evaluate small-molecule orexin receptor agonists as preclinical leads for the t See details	National Institutes of Health	9/25/2009
EDUCATION SERVICE CENTER REGION 10	$937,619	ARRA - Head Start Head Start promotes the school readiness of low income children through the provision of comprehensive health, developmental and family services. The Region 10 Education Service Center Head Start program received 54 additional slots to serve three and fo See details	Administration for Children and Families	9/18/2009
University of Texas Southwestern Medical Center At Dallas	$919,078	Trans-NIH Recovery Act Research Support This application requests continued support for the NIEHS Center at the University of Texas Medical Branch. The mission of this Center is to integrate, coordinate and foster interactions and collaborations among a group of established investigators pursui This spending item is part of a $932,328 allocation. See details	National Institutes of Health	9/07/2009
DALLAS COUNTY LOCAL WORKFORCE DEVELOPMENT BOARD, INC.	$897,282	ARRA Child Care and Development Block Grant ARRA Supplemental Funding for the Child Care and Development Fund (CCDF) provides child care financial assistance to low-income working families and fund activities to improve the quality of child care. This spending item is part of a $214,851,599 allocation. See details	Administration for Children and Families	4/09/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$894,058	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant):: The objective of this application is the purchase of a BioScan NanoSPECT-CT scanner for in vivo small animal scanning. The requested purchase price is $1,063,916. Acquisition of the scanner will fulfill an unmet campu See details	National Institutes of Health	7/08/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$865,671	Trans-NIH Recovery Act Research Support Broad spectrum anti-viral agents are being developed for the treatment of hemorrhagic fevers caused by use of arenaviruses as biological weapons. The new anti-viral agents are human antibodies that eliminate virally-infected cells and viruses, assisting i See details	National Institutes of Health	8/13/2009
RETINA FOUNDATION OF THE SOUTHWEST	$852,646	Trans-NIH Recovery Act Research Support Congenital and early onset binocular imbalance, including esotropia, anisometropia, and cataracts, affect 2-4% of infants in the U.S. Early binocular imbalance can cause amblyopia and abnormal binocular vision. Over 90% of patients with congenital and ear See details	National Institutes of Health	6/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$826,531	Trans-NIH Recovery Act Research Support Drug addiction is a major illness that penetrates beyond the afflicted individual to families and communities, having adverse effects on millions of people. It exacts enormous costs on our nation?s health care system, economy, and overall productivity. Th See details	National Institutes of Health	7/16/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$785,000	Trans-NIH Recovery Act Research Support The gene in question codes for a protein called ?B1? which in its abnormal state will change the composition in the urine resulting in kidney stone formation. We will use human population and laboratory studies to answer three questions. 1. Exactly how co See details	National Institutes of Health	9/11/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$785,000	Trans-NIH Recovery Act Research Support Autoimmune diseases (for example, rheumatoid arthritis) affect millions of individuals worldwide and thus represent a significant health challenge. Both the damage and control processes in autoimmune disease involve special white blood cells (T cells) abl See details	National Institutes of Health	8/11/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$785,000	Trans-NIH Recovery Act Research Support Public narrative statement: the aim of this project is to understand pathogenic mechanisms responsible for Alzheimer's disease - an incurable disorder that affects large portion of the aging population See details	National Institutes of Health	8/14/2009
AMERICAN HEART ASSOCIATION, INC.	$784,878	ARRA - Prevention and Wellness - Leveraging National Organizations Provide technical assistance in the implimentation of obesity prevention projects to both assigned and unassigned communities under the Communities Putting Prevention to Work (CPPW) program. This spending item is part of a $963,750 allocation. See details	Health and Human Services, Department of	7/13/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$767,805	Trans-NIH Recovery Act Research Support The origins of human diseases, such as cancer, can be generally attributed to loss-of-function of important genes (tumor suppressor genes) and/or gain-of-function of pathological genes (oncogenes). We are interested in understanding how animal cells use s See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$765,335	Trans-NIH Recovery Act Research Support The proposed project should have a positive impact on human health because elucidating molecular mechanisms that regulate sperm stem cell development will lead to treatments and cures for male infertility, provide new targets for contraceptive development See details	National Institutes of Health	9/22/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$745,716	Trans-NIH Recovery Act Research Support Amyloid is the dangerous brain plaque and tau protein tangles with in the brain cells tend to prevent neurons from communicating each other leading to loss of memory. Positron emission tomography (PET scan) can create image of the harmful beta amyoid plaq See details	National Institutes of Health	9/24/2009
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON	$703,890	Trans-NIH Recovery Act Research Support Minority children are more likely to experience early academic failure than are non-minority children. Increased risk of academic failure is associated with a host of family factors such as family poverty, maternal depression, low maternal education, and This spending item is part of a $1,342,403 allocation. See details	National Institutes of Health	9/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$698,491	Trans-NIH Recovery Act Research Support A Core Center Grant is proposed to support vision research at The University of Texas Southwestern Medical Center. The recent expansion of vision research on our campus has created an opportunity to enhance visual science research at U.T. Southwestern Med See details	National Institutes of Health	6/10/2010
UNIVERSITY OF TEXAS AT DALLAS	$691,787	Trans-NIH Recovery Act Research Support This proposal is a response to NOT-OD-058, 'NIH Announces the Availability of Recover Act Funds for Competitive Revision Applications.' It utilizes new neuroimaging advances (including amyloid imaging) that were not even available to the project at the ti This spending item is part of a $894,213 allocation. See details	National Institutes of Health	9/24/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$675,660	Trans-NIH Recovery Act Research Support The pancreas secretes digestive enzymes and fluid that contains a lot of HCO3 that wash the enzymes to theintestine. The HCO3 is needed to prevent premature activation of the e See details	National Institutes of Health	9/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$651,553	Trans-NIH Recovery Act Research Support The proposed project should have a positive impact on human health; elucidating molecular mechanisms that regulate spermatogonial development may well lead to treatments and cures for male infertility, provide new targets for contraceptive development, as See details	National Institutes of Health	9/22/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$651,550	Trans-NIH Recovery Act Research Support Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related death. Novel therapeutic strategies are urgently needed. With this proposal, we are planning to move toward this goal by gaining a better understanding of the molecular networks that See details	National Institutes of Health	5/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$651,548	Trans-NIH Recovery Act Research Support The experiments proposed in this study were designed to investigate the role played by the phosphatidylinositol 3-kinase (PI3K) signaling pathways mediating leptin action on reproduction. These studies were proposed to better understand the role of the ad See details	National Institutes of Health	9/22/2009
UNIVERSITY OF TEXAS AT DALLAS	$638,513	Trans-NIH Recovery Act Research Support Minority children are more likely to experience early academic failure than are non-minority children. Increased risk of academic failure is associated with a host of family factors such as family poverty, maternal depression, low maternal education, and This spending item is part of a $1,342,403 allocation. See details	National Institutes of Health	9/29/2009
BAYLOR RESEARCH INSTITUTE, THE	$632,282	Recovery Act Comparative Effectiveness Research - AHRQ Comparative effectiveness research (CER) requires that clinical data be in standard forms allowing multiple, large databases to be efficiently combined, and requires that all of the data be coded so that automated summarization of the data is posossible. H... Show more This spending item is part of a $8,696,942 allocation. See details	Agency for Healthcare Research and Quality	9/28/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$611,429	To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders. This spending item is part of a $16,872,951 allocation. See details	National Institutes of Health	7/13/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$605,549	Trans-NIH Recovery Act Research Support Acute kidney injury has high morbidity and high mortality. There is no specific and effective treatment at the present time. Stem cells offer therapeutic potential for kidney disease. The goal of this application is to develop cell therapeutic agents from See details	National Institutes of Health	9/21/2009
UNIVERSITY OF TEXAS AT DALLAS	$598,384	Trans-NIH Recovery Act Research Support A significant potential exists to modify the structure and function of the aging human brain given intensive mental stimulation and physical activity. Age-related cognitive decline has consistently been identified on frontal lobe measures of executive con This spending item is part of a $1,000,000 allocation. See details	National Institutes of Health	9/22/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$565,788	Trans-NIH Recovery Act Research Support The purpose of this award is to 1) define the repression mechanism of E2-Brd4 in HPV Chromatin and 2) to define the role of E2-P.85 in HPV Chromatin Transcription. We will explore this possibility using our in vitro-reconstituted HPV chromatin transcri See details	National Institutes of Health	7/22/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$549,500	Trans-NIH Recovery Act Research Support Autism spectrum disorders (ASDs) are common, debilitating disorders affecting social interaction, communication, and repetitive behaviors. Recent genetic findings have identified mutations in synaptic cell adhesion genes and genes encoding their interacti See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$549,500	Trans-NIH Recovery Act Research Support Drug addition is a devastating disease affecting millions of people in the United States. The studies outlined in this proposal are aimed at identifying and characterizing novel components of the signaling pathways that underlie the molecular basis of dr See details	National Institutes of Health	9/30/2009
PARKLAND HEALTH & HOSPITAL SYSTEM	$538,505	ARRA Health Center Integrated Services Development Initiative[g1] ARRA Capital Improvement Project. The HOMES program delivers health care to homeless individuals and families in Dallas County through the use of four mobile medical units and a fixed site clinic. The mobile units range in age from ththree to thirteen year... Show more See details	Health Resources and Services Administration	6/25/2009
NORTH TEXAS ACCOUNTABLE HEALTHCARE PARTNERSHIP	$535,288	ARRA - State Grants to Promote Health Information Technology STATE HEALTH INFORMATION EXCHANGE COOPERATIVE AGREEMENT PROGRAM: The governance, policy and technical infrastructure supported through this program will enable standards-based Health Information Exchange (HIE) and a high performance health h care system. Th... Show more This spending item is part of a $28,810,208 allocation. See details	Health and Human Services, Department of	3/15/2010
EDUCATION SERVICE CENTER REGION 10	$534,786	ARRA - Head Start Head Start/Early Head Start - provide cost of living salary adjustments and associated benefits to Head Start staff members, materials and supplies for program operation, and stipends for training. See details	Administration for Children and Families	7/10/2009
BAYLOR RESEARCH INSTITUTE, THE	$527,374	Trans-NIH Recovery Act Research Support In collaboration with scientists at the Unversity of Texas MD Anderson Cancer Center, we will test our immunotherapeutic approach to treating HPV related cancers in a non-human primate model. This study fulfills the premises of the Grand Opportunity Grant This spending item is part of a $980,587 allocation. See details	National Institutes of Health	9/30/2009
LOS BARRIOS UNIDOS COMMUNITY CLINIC, INC.	$523,803	ARRA Health Center Integrated Services Development Initiative[g1] The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underserved area or for an underserved population. See details	Health Resources and Services Administration	3/27/2009
LOS BARRIOS UNIDOS COMMUNITY CLINIC, INC.	$523,803	ARRA Health Center Integrated Services Development Initiative[g1] The purpose of this award is to expand access to needed primary health care services specifically by expanding services at existing health center sites in an underserved area or for an underserved population. See details	Health Resources and Services Administration	3/27/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$521,598	Trans-NIH Recovery Act Research Support Eleven total Yucatan Minipigs have been ordered and received. All animals underwent a course of oral antibiotics for bone-labeling. Following antibiotics, a bone biopsy procedure was performed taking core bone samples from the fourth cervical vertebral b This spending item is part of a $596,418 allocation. See details	National Institutes of Health	9/15/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$514,960	Trans-NIH Recovery Act Research Support Our recent studies have suggested that phosphate is an accelerator of aging. The purpose of this supplement is to test if aging processes can be suppressed by low phosphate diet and accelerated by high phosphate diet in a mouse model of aging. If succes See details	National Institutes of Health	9/29/2009
MARTIN LUTHER KING JR FAMILY CLINIC INC	$508,265	ARRA Health Center Integrated Services Development Initiative[g1] The MLK Family Clinic will have a totally new updated and state-of-the-art IT/HIT/EHR system (including hardware, supporting software, and system equipment accessories) in place with the addition of this project. The EHR phase of a newew Practice Management... Show more See details	Health Resources and Services Administration	6/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$507,124	Trans-NIH Recovery Act Research Support Understanding and manipulating gene expression in distinct fat pads as distinct clusters of genes remains a major challenge. We propose that the physiological properties of a given fat pad are the result of the discrete regulation of a relatively small nu This spending item is part of a $999,998 allocation. See details	National Institutes of Health	9/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$502,832	Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic 04-AR-101 Autoimmunity for Diseases of Skin, Joints, Muscles and Other Tissues. It is estimated that approximately 5% of the US population is affected by a This spending item is part of a $974,414 allocation. See details	National Institutes of Health	9/21/2009
BAYLOR RESEARCH INSTITUTE, THE	$499,875	Trans-NIH Recovery Act Research Support This work will address the challenge in human mucosal immunology. It will have a broad impact in science and health as it will provide fundamental knowledge in the immunology of the human genital tract, particularly the vagina, which is a major site of in See details	National Institutes of Health	9/29/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$499,749	Trans-NIH Recovery Act Research Support One form of frontotemporal dementia (FTD) is frequently caused by nonsense mutations in a presumed signaling protein, Progranulin (GRN). This project aims to develop and perform preclinical testing of a combinatorial drug treatment approach that aims at r This spending item is part of a $999,749 allocation. See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$499,099	Trans-NIH Recovery Act Research Support The long-term goal of this project is to understand how mutations in voltage-gated ion channels cause episodic weakness and stiffness in several heritable forms of periodic paralysis and myotonia. See details	National Institutes of Health	9/28/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$497,026	Trans-NIH Recovery Act Research Support The goal of this proposal is to obtain funds for a Leica TCS SP5 MP Fixed stage (UV- VIS-IR) confocal microscope for the Baylor College of Dentistry (BCD) light microscopy core facility. This instrument will be used to examine the gene expression and prot See details	National Institutes of Health	4/22/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$493,756	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Next-generation sequencing (NGS) provides a powerful new technology to rapidly and effectively interrogate DNA sequence in a simple, comprehensive and cost-effective manner. Probing patterns of whole genome expression, See details	National Institutes of Health	5/27/2010
UNIVERSITY OF TEXAS AT DALLAS	$474,132	Trans-NIH Recovery Act Research Support The central hypothesis of this proposal is that cysteine is a significant cause of oxidative stress without oxygen, and that reactive sulfur species (RSS) mediate this stress. Because some of the most notorious pathogens have a particular enzyme to mainta See details	National Institutes of Health	7/31/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$471,000	Trans-NIH Recovery Act Research Support These studies will address the role of therapy-induced immune regulation in the immunology of Multiple Sclerosis. We believe that the results from such an evaluation will provide greater insight into the complex processes that underlie the regulation of See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS AT DALLAS	$468,632	Trans-NIH Recovery Act Research Support Perhaps the most urgent scientific challenge for the 21st century is to develop interventions to slow the process of cognitive aging so that at the end of life, most older adults are in control of their mental faculties and they and their families can enj This spending item is part of a $773,299 allocation. See details	National Institutes of Health	9/23/2009
SOUTHERN METHODIST UNIVERSITY INC	$452,326	Trans-NIH Recovery Act Research Support Parkinson's disease (PD) is a neurodegenerative disorder characterized by death of substantia nigra (SN) dopamine neurons (DANs), dopamine deficiency within the striatum and a clinical movement disorder. Most PD is sporadic/idiopathic that may arise from This spending item is part of a $3,907,801 allocation. See details	National Institutes of Health	9/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$431,750	Trans-NIH Recovery Act Research Support In the last decade, significant advances have been made toward achieving chemical control of key developmental signal transduction pathways that are frequently corrupted in cancer. Given the promise of these therapeutic strategies and the perils that they See details	National Institutes of Health	9/04/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$431,750	Trans-NIH Recovery Act Research Support Hypertension is a major cause of morbidity and mortality in the United States, especially in the African American population where the prevalence, consequences, and severity of hypertension are at their highest; making strategies for its control and treat See details	National Institutes of Health	9/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$431,750	Trans-NIH Recovery Act Research Support We have recently developed potassium channel-mutant mice that are very sensitive to low concentrations of alcohol. Hence, these mice will serve as well-defined rodent models to study the electrophysiological changes, i.e., altered neuronal firing patterns See details	National Institutes of Health	9/04/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$431,750	Trans-NIH Recovery Act Research Support Influenza virus must hijack proteins present within the cells of the human mucosa in order to reproduce in infected individuals. A detailed understanding of the mucosal cell proteins required to support viral replication as well as those which are mobiliz See details	National Institutes of Health	9/11/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$431,354	Trans-NIH Recovery Act Research Support Inhibition of androgen synthesis is the current treatment of human diseases like prostate cancer and polycystic ovary syndrome. This approach is suboptimal. By defining how the enzyme responsible synthesizes these androgens, we hope to establish new appro See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$410,602	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The UT Southwestern high-throughput screening (HTS) laboratory creates and conducts screens of small molecules to identify those that can become leads for developing therapeutics or used as tools in research. In additi See details	National Institutes of Health	4/29/2010
GREATER DALLAS COUNCIL ON ALCOHOL AND DRUG ABUSE	$399,334	ARRA - Prevention and Wellness--State Territories and Pacific Islands Grant funds to establish or improve initiatives in communities and schools throughout the state. State efforts will promote evidence based interventions at the state and local levels to establish healthy social norms, provide healalthier, affordable choices... Show more This spending item is part of a $2,200,000 allocation. See details	Centers for Disease Control and Prevention	2/06/2010
UNIVERSITY OF TEXAS AT DALLAS	$394,049	Trans-NIH Recovery Act Research Support Intracellular imaging and targeted delivery demand new nanomaterials that can directly cross cell membranes and enter the cytosol without being encapsulated by membrane bound vesicles. We recently found that highly luminescent, gold nanoparticles about 2 See details	National Institutes of Health	7/14/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$392,500	Trans-NIH Recovery Act Research Support Basic biomedical research to understand the function of T lymphocytes. These are the central regulatory cell of the immune system, the part of our body that fights off viruses, pathogenic bacteria, and parasites. The grant is entitled 'A quantitative unde See details	National Institutes of Health	6/19/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$391,368	Trans-NIH Recovery Act Research Support Our overall hypothesis is that PI4KII? (phosphatidylinositol 4 kinase II?), which produces more than 50% of the phosphatidylinositol 4 phosphate (PI4P) in the Golgi, regulates Golgi functions through its localized production of PI4P. The PI4P itself estab See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$386,002	Trans-NIH Recovery Act Research Support The identification of a basic-rich motif in the cytoplasmic tail of the CD3e subunit could represent an important breakthrough in our understanding of how complex multi-subunit receptors are assembled, recycled, and signal. Preliminary results demonstrat See details	National Institutes of Health	7/22/2009
TEXAS A&M UNIVERSITY SYSTEM,THE	$381,086	Trans-NIH Recovery Act Research Support Lichen Planus (LP) is a chronic, inflammatory--and, so far, incurable--disease of unknown etiology, affecting skin and mucosa of approximately 2% of the population. Because several clinical studies have indicated that LP patients have an increased risk fo See details	National Institutes of Health	4/29/2009
BAYLOR RESEARCH INSTITUTE, THE	$375,597	Trans-NIH Recovery Act Research Support This application is for funding of a study to characterize the human immune response before and after 2010-2011 influenza A/California/H1N1 seasonal vaccination by developing comprehensive immune profiles utilizing systems biology and bioinformatics appro This spending item is part of a $3,496,853 allocation. See details	National Institutes of Health	7/12/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$371,319	Trans-NIH Recovery Act Research Support These investigations will further define potential roles for new visual function tests and ocular imaging measures as potential outcomes for MS clinical trials, and will apply paradigms from MS vision research to acute ON as a more specific model for asse This spending item is part of a $1,296,171 allocation. See details	National Institutes of Health	6/03/2009
TEXAS A&M UNIVERSITY SYSTEM,THE	$355,263	Trans-NIH Recovery Act Research Support The research proposed in this competitive revision application as well as the parent grant application focuses on dentin matrix protein 1 (DMP1) and dentin sialophosphoprotein (DSPP), two non-collagenous extracellular matrix (ECM) proteins that belong to See details	National Institutes of Health	9/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$341,714	Trans-NIH Recovery Act Research Support Background. The ability of short interfering RNAs (siRNAs) to recognize mRNA is widely appreciated. siRNAs are entering Phase 1 trials, but their ultimate potential to impact human health is unclear. The overall goal of the parent proposal GM 77253 was to See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS AT DALLAS	$327,615	Trans-NIH Recovery Act Research Support The research project plans to perform a comprehensive detection of fusion transcripts in acute myeloid leukemia, with the aims to identify new genes contributing to this disease and to identify new markers for clinical diagnosis, treatment and prognosis o This spending item is part of a $705,133 allocation. See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$327,405	Trans-NIH Recovery Act Research Support Obesity is a worldwide health epidemic and a major contributor to the increased prevalence and severity of more than 60 metabolic, inflammatory, degenerative, cognitive, and neoplastic disorders. Broadly effective preventive and therapeutic strategies hav This spending item is part of a $3,811,268 allocation. See details	National Institutes of Health	9/30/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$324,877	Trans-NIH Recovery Act Research Support The main hypothesis of the proposal is that a combination of anatomic and functional abnormalities of the arterial and venous circulations of the upper extremities, predict arteriovenous fistula maturation failure in patients with a stage 4 and 5 chronic See details	National Institutes of Health	9/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$322,892	Trans-NIH Recovery Act Research Support This projects seeks to understand the membrane biology of Treponema pallidum through elucidation of the organisms membrane liproproteins. Such structure and function information could be central to the rational design of a future syphillis vaccine. See details	National Institutes of Health	8/13/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$315,963	Trans-NIH Recovery Act Research Support Neurospora crassa, which has one of the best understood systems in clock function and light entrainment, offers an excellent experimentally-accessible paradigm for undertanding the clock mechanism. These studies will help us to describe the molecular and See details	National Institutes of Health	9/09/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$309,516	Trans-NIH Recovery Act Research Support The Acute Liver Failure Study Group (ALFSG) has been funded by NIDDK since 1997 to study a rare condition, acute liver failure. Only a network approach will capture these unusual but life threatening cases. ALFSG provides a registry including data and bio This spending item is part of a $425,660 allocation. See details	National Institutes of Health	5/31/2010
COOPER INSTITUTE, THE	$307,416	Trans-NIH Recovery Act Research Support A significant potential exists to modify the structure and function of the aging human brain given intensive mental stimulation and physical activity. Age-related cognitive decline has consistently been identified on frontal lobe measures of executive con This spending item is part of a $1,000,000 allocation. See details	National Institutes of Health	9/22/2009
COMMUNITY COUNCIL OF GREATER DALLAS INC	$306,151	Aging Congregate Nutrition Services for States ARRA provided funding for Congregate Nutrition Services. Established in 1972 under the Older Americans Act, the program provides meals to older Americans in congregate facilities such as senior centers, adult day centers, and faith-based settings. This spending item is part of a $4,012,217 allocation. See details	Administration on Aging	3/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$304,667	Trans-NIH Recovery Act Research Support Perhaps the most urgent scientific challenge for the 21st century is to develop interventions to slow the process of cognitive aging so that at the end of life, most older adults are in control of their mental faculties and they and their families can enj This spending item is part of a $773,299 allocation. See details	National Institutes of Health	9/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$297,188	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Multiple sclerosis (MS) is an inflammatory, demyelinating disorder of the central nervous system (CNS) and is responsible for long-term morbidity in over 300,000 people in the United States. Although the precise etiolo See details	National Institutes of Health	8/02/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$295,533	Trans-NIH Recovery Act Research Support Ultrasound offers unique capabilities for investigating tumor development in terms of anatomy and perfusion. The new instrument will accelerate development of new therapies in our institution, which will be directly translatable to the clinic, and thus, p See details	National Institutes of Health	4/28/2009
UNIVERSITY OF TEXAS AT DALLAS	$290,712	Trans-NIH Recovery Act Research Support There is a considerable amount of social and behavioral data that is correlational in nature suggesting that individuals who are deeply engaged in social and intellectual activities in mid and late adulthood show delays in normal age-related cognitive dec See details	National Institutes of Health	8/12/2009
SCENPRO, INC.	$282,574	The Cancer Knowledge Cloud will connect and share information generated through NCI genomic atlas projects, the caHUB tissue acquisition network, the NCI functional Biology Consortium, NCI patient Characterization Center, the NCI pre-clinical Development This spending item is part of a $103,000,000 allocation. See details	National Institutes of Health	11/23/2009
BAYLOR RESEARCH INSTITUTE, THE	$282,143	Trans-NIH Recovery Act Research Support The PROMISSE Study (Predictors of Pregnancy Outcome: bioMarkers In antiphospholipid antibody Syndrome Systemic lupus Erythematosus) is a multi-center, prospective observational study designed to characterize the mechanisms of antiphospholipid (APL) antibo This spending item is part of a $469,996 allocation. See details	National Institutes of Health	9/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$280,869	Trans-NIH Recovery Act Research Support Malfunction of the spindle checkpoint has been implicated in human cancers. The class of antimitotic anti-cancer drugs, such as Taxol, kills cancer cells by exploiting defects in this pathway. The proposed experiments will shed light on the molecular ba See details	National Institutes of Health	8/13/2009
TEXAS A&M UNIVERSITY SYSTEM,THE	$274,764	Trans-NIH Recovery Act Research Support The development of dentition involves a complex series of epithelial-mesenchymal signaling interactions. It is not surprising that such a process is prone to disturbances which then manifest as congenital tooth agenesis in up to 10% of the population and This spending item is part of a $362,874 allocation. See details	National Institutes of Health	9/01/2009
PARKLAND HEALTH & HOSPITAL SYSTEM	$270,861	ARRA Health Center Integrated Services Development Initiative[g1] ARRA Increase Services to Health Centers. In May 2008, the HOMES program moved its fixed site from a closed facility to The Bridge, the new homeless assistance center. Prior to the move the clinic averaged 184 new patients and 344 vivisits per month. The... Show more See details	Health Resources and Services Administration	3/27/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$266,900	Trans-NIH Recovery Act Research Support Our specific aims are to 1) Investigate the mechanisms through which viral proteins disrupt the mRNA export machinery; 2) To study regulation of mRNA export by antagonists of viral-mediated mRNA export block; and 3) To determine the role of mRNA export i See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$266,510	Trans-NIH Recovery Act Research Support Our laboratory uses the biflagellated green alga Chlamydomonas reinhardtii as a model system to study cilium-generated signaling and ciliary/flagellar shortening. During the Chlamydomonas mating reaction, adhesion receptors (agglutinins) on the flagella See details	National Institutes of Health	8/14/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$260,000	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The objectives of this proposal are to purchase a state-of-the-art multiplex assay system for the detection of soluble molecules (cytokines, growth factors, metabolic markers, hormones, mediators of inflammation, other See details	National Institutes of Health	7/29/2010
QED CLINICAL, INC.	$252,475	Recovery Act Comparative Effectiveness Research - AHRQ The overall goals of this project are to enhance the capacity and capability of a safety net focused distributed research network to conduct prospective comparative effectiveness research via a multi-setting, multi-state organization. The Scalablble Archite... Show more This spending item is part of a $8,309,543 allocation. See details	Agency for Healthcare Research and Quality	9/28/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$248,289	We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr This spending item is part of a $1,627,009 allocation. See details	National Institutes of Health	9/27/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$247,275	Trans-NIH Recovery Act Research Support We propose to study chimeras of MscL orthologues with distinct functional characterists. In addition, we propose to define potential changes in protein-lipid (or other hydrophobic) interactions that occur upon MscL gating by screening a cysteine library See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$246,930	Trans-NIH Recovery Act Research Support These studies will lead to a more comprehensive understanding of how EpoR signals through JAK2 to regulate erythropoiesis, and how JAK2 mutations contribute to myeloproliferative disorders and lukemia. See details	National Institutes of Health	8/01/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$239,970	Trans-NIH Recovery Act Research Support The Coordinating and Bioinformatics Unit (CBU) for the Animal Models of Diabetic Complications Consortium (AMDCC) and the Mouse Metabolic Phenotyping Centers (MMPC) is responsible for creating and maintaining the administrative, scientific and informatics This spending item is part of a $1,819,749 allocation. See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$238,978	Trans-NIH Recovery Act Research Support The focus of this research is to study the intracellular trafficking during visual system development in Drosophila. Our goal is to identify and characterize intracellular trafficking compartments and pathways that instruct synaptic specificity. See details	National Institutes of Health	9/30/2009
MARTIN LUTHER KING JR FAMILY CLINIC INC	$238,685	ARRA Health Center Integrated Services Development Initiative[g1] MLK Jr. Family Clinic applied for and received funds under the ARRA Increased Demand for Services in order to address the access demand experienced in the Dallas County area. More and more patients needed options for affordable healththcare, and MLK Jr. Fa... Show more See details	Health Resources and Services Administration	3/27/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$237,750	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Evolutionary pressure has favored mechanisms that allow the body to efficiently store nutrients as fat when food is abundant as a safeguard against occasional famine. With the dramatic changes in modern lifestyle inclu See details	National Institutes of Health	2/02/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$237,750	Trans-NIH Recovery Act Research Support Drug addiction is a devastating disorder marked by compulsive drug use, high propensity to relapse to drug taking, and cognitive deficits. Drugs of abuse, including morphine, lead to a decrease in the number of new neurons in the hippocampus, a brain regi See details	National Institutes of Health	9/27/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$237,750	Trans-NIH Recovery Act Research Support While the thiazolidinedione (TZD) drugs are widely used to treat type 2 diabetes, how they work and cause their side effects is not fully understood. Here we will examine how the hormone, FGF21, contributes to the beneficial and harmful effects of TZDs. I See details	National Institutes of Health	7/05/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$237,750	Trans-NIH Recovery Act Research Support PROJECT NARRATIVE In the proposed research, we will focus on defining the genetic and epigenetic mechanisms that mediate expression of aromatase, the key enzyme in estrogen synthesis, in placenta and in breast cancer. In view of the suggested role of inad See details	National Institutes of Health	7/05/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$233,551	Trans-NIH Recovery Act Research Support The Pelvic Floor Disorders Network (PFDN) is a cooperative multi-center network of clinical sites and a Data Coordinating Center (DCC) directed by a Steering Committee composed of the principal investigators of the clinical sites and DCC and the NIH Proje See details	National Institutes of Health	9/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$231,447	Trans-NIH Recovery Act Research Support We aim to synthesize marine metabolites with potential clinical applications. The focus of this research is the synthesis of biologically significant and synthetically challenging natural pyrrole-imidazole alkaloids, in particular, massadine, a newly disc See details	National Institutes of Health	2/05/2010
UNIVERSITY OF TEXAS AT DALLAS	$229,500	Trans-NIH Recovery Act Research Support Peptides and proteins play fundamental roles in regulating critical biochemical pathways and often use helical structures to exert their functions. This recognizes that small molecules which can accurately represent helical structures would be of great va See details	National Institutes of Health	1/19/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$228,568	Trans-NIH Recovery Act Research Support Telomere lengths of human chromosomes shorten with age. Accelerated telomere shortening is associated with multiple different diseases of older adults such as pulmonary fibrosis, atherosclerosis and osteoporosis. Measurement of telomere lengths in a la See details	National Institutes of Health	7/16/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$227,316	Trans-NIH Recovery Act Research Support Lung cancer is the leading cause of cancer-related deaths, with the majority of deaths due to failed therapy from tumor drug resistance. As described in the original application, we have developed a microarray screen for identifying differentially express See details	National Institutes of Health	9/15/2009
HEAD START OF GREATER DALLAS INC	$225,000	ARRA - Early Head Start Coaches, through research based practive, will mentor teaching staff to increase educational outcomes of HS and EHS children. The teachers will provide enhanced curriculum implementation from an individualized teaching framework. See details	Administration for Children and Families	9/17/2010
SOUTHERN METHODIST UNIVERSITY INC	$218,250	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Many oncogenic viruses interact with cellular oncoproteins to induce cancers in humans. It is of paramount importance to understand the mechanisms by which transforming viruses cooperate with host factors to promote ne See details	National Institutes of Health	6/08/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$215,903	Trans-NIH Recovery Act Research Support For two years, four investigators will each hire a new full-time employee to identify and validate a novel therapeutic strategy for a group of rare inherited metabolic disorders, the Congenital Disorders of Glycosylation-Type I (CDG-I). These disorders re This spending item is part of a $999,141 allocation. See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$212,753	Trans-NIH Recovery Act Research Support The proposed work represents an entirely unique area of kidney research that has not been previously interrogated in either the laboratory or the clinic. By investigating a novel SERM of which level rise progressively with age, this proposed project has This spending item is part of a $276,813 allocation. See details	National Institutes of Health	8/12/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$211,950	Trans-NIH Recovery Act Research Support Atherosclerosis is a disease of chronic inflammation of the arterial wall, resulting from complex interactions between modified lipoproteins, macrophages, T lymphocytes, endothelial, and smooth muscle cells. Complications of atherosclerosis such as myocar See details	National Institutes of Health	7/20/2009
UNIVERSITY OF TEXAS AT DALLAS	$208,873	Trans-NIH Recovery Act Research Support The proposal plans to perform a comprehensive detection of fusion transcripts in acute myeloid leukemia, with the aims to identify new genes contributing to this disease and to identify new markers for clinical diagnosis, treatment and prognosis of this d This spending item is part of a $509,211 allocation. See details	National Institutes of Health	3/04/2011
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$206,603	The Systolic Blood pressure Intervention Trial, (SPRINT) contractor will conduct a multicenter, randomized clinical trial to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease. This spending item is part of a $2,491,798 allocation. See details	National Institutes of Health	9/24/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$206,116	Recovery Act Comparative Effectiveness Research - AHRQ 'In response to RFA-10-003: AHRQ Clinical and Health Outcomes Initiative in Comparative Effectiveness: the goal of this project is to conduct a randomized controlled multi-center clinical trial to determine whether using the Online Wound Electrononic Medica... Show more This spending item is part of a $9,645,674 allocation. See details	Agency for Healthcare Research and Quality	9/28/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$202,426	Trans-NIH Recovery Act Research Support This proposal is a response to NOT-OD-058, 'NIH Announces the Availability of Recover Act Funds for Competitive Revision Applications.' It utilizes new neuroimaging advances (including amyloid imaging) that were not even available to the project at the ti This spending item is part of a $894,213 allocation. See details	National Institutes of Health	9/24/2009
PRESBYTERIAN HOSPITAL OF DALLAS	$201,505	Trans-NIH Recovery Act Research Support Given the lack of information regarding short and long term consequences of skin grafting with respect to revascularization and reinnervation of the grafted skin, the primary objective of this proposal is to test the hypothesis that autonomic and non-auto This spending item is part of a $208,005 allocation. See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$200,415	Trans-NIH Recovery Act Research Support Mutation in the gene for the ABCA3 transporter cause a variety of lung diseases that result in either death in the immediate newborn period or chronic lung disease in children and into adulthood. We have created mouse models of the human ABCA3 mutations See details	National Institutes of Health	7/15/2009
EDUCATION SERVICE CENTER REGION 10	$200,000	ARRA - Early Head Start Early Learning Mentor Coach Project - The Early Head Start program provides family-centered services for low-income families with very young children (pre-birth to 3) to promote the healthy development of the children and families. The Region 10 ESC Earl See details	Administration for Children and Families	9/16/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$199,852	Trans-NIH Recovery Act Research Support The specific aims of this proposal revolve around the need to understand how this multifunctional pathway performs funtctions that are ligand specific at selected sites of action. We know a great deal about this pathway, but not nearly enough to underst See details	National Institutes of Health	12/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$199,830	Trans-NIH Recovery Act Research Support The overall purpose of the award is to accelerate progress on NIH grant HL085218. The expected outcome is an increase in research conducted under HL085218. It is expected that one additional submission to a peer reviewed journal will be made during the pe See details	National Institutes of Health	7/20/2009
UNIVERSITY OF TEXAS AT DALLAS	$187,428	Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08- MH-103: Understanding the genomic risk architecture of mental disorders. Rett syndrome (RTT), caused by mutations in the X-linked gene encoding methyl-CpG-bind This spending item is part of a $1,012,457 allocation. See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$181,906	Trans-NIH Recovery Act Research Support We have demonstrated that postsynaptic activity in muscles regulate the development of Schwann cells and the onset of myelination. Further investigation may reveal novel mechanisms of myelination and provide important insights for a better understanding See details	National Institutes of Health	8/11/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$181,076	Trans-NIH Recovery Act Research Support Acute liver failure is a rare but devastating disease that has been studied for 11 years by our established consortium of 23 academic centers. We now propose an administrative supplement to support more intensive management of all aspects of the data and This spending item is part of a $235,366 allocation. See details	National Institutes of Health	9/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$180,722	Trans-NIH Recovery Act Research Support The function of lysosomes and lysosome-related organelles is critical to human health as confirmed by many human genetic disorders and pathogen-induced illnesses that disrupt these processes. Our ongoing genetic, biochemical and cell-biological experimen See details	National Institutes of Health	9/23/2009
CHILDCAREGROUP	$180,305	ARRA - Head Start Grant was awarded to fund a temporary cost-of-living adjustment (COLA) increase for both Head Start and Early Head Start employees; provide quality improvement funds to improve compensation and qualifications/skills of educational personnel including thos This spending item is part of a $2,234,481 allocation. See details	Administration for Children and Families	6/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$176,824	Trans-NIH Recovery Act Research Support The main focus of the parent grant application is to understand the immunologic interactions that mediate the modulatory effects of this FDA-approved therapy, thereby uncovering important aspects of intrinsic immune regulation. See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$175,840	Trans-NIH Recovery Act Research Support The purpose of this application is to request support that was lost from the original budget needed to perform the studies outlined in Specific Aim #3, as well as additional support to augment our proposed studies outline in Specific Aim 3 of our parent g See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$171,768	Trans-NIH Recovery Act Research Support 'The roles of the V-ATPase at the molecular and physiological level will be investigated. The V0 sector subunit G?aG? has been shown to play important roles in diverse membrane fusion or secretion functions independent of the V-ATPase proton-pumping activ This spending item is part of a $970,890 allocation. See details	National Institutes of Health	9/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$163,301	Trans-NIH Recovery Act Research Support Overall Purpose and expected outcome. Funds provided by the Recovery Act will allow us to complete work begun during the past five years in order to advance clinical research on the effects and effectiveness of pharmaceuticals in child health. The funds See details	National Institutes of Health	7/16/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$157,000	Trans-NIH Recovery Act Research Support Our goal is to analyze a range of disease severities. The database provides a unique resource to obtain a large number of multi-variate datasets for correlation analysis. The sample size in each subgroup is approximate, depending on data availability and See details	National Institutes of Health	5/08/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$157,000	Trans-NIH Recovery Act Research Support This application is to find out why kallikreins are regulated and how they exert protective effect against immune nephritis. Finally we will develop a mouse model in which we can control the kallikreins expression specifically in kidney during specific di See details	National Institutes of Health	6/10/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$157,000	Trans-NIH Recovery Act Research Support We propose to isolate a new generation of antibiotics that would be ideal for treating multi-drug resistant and otherwise difficult to treat infections. The antibiotics isolated could also have implications in emergency situations including treating victi See details	National Institutes of Health	5/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$157,000	Trans-NIH Recovery Act Research Support We propose to continue our studies of the biochemical and biophysical mechanisms used by G protein signaling modules to organize, integrate and transmit information. The diversity, number and ubiquity of G protein-coupled receptors (GPCRs) account for the See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$157,000	Trans-NIH Recovery Act Research Support The increasing incidence of obesity is a major health issue facing the USA. Moreover, the mechanisms underlying anorexia nervosa remain poorly understood. Fortunately, in the past decade several key hormones and CMS pathways controlling body weight and gl See details	National Institutes of Health	4/12/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$156,083	Trans-NIH Recovery Act Research Support The proposed program will provide a genuine, goal-oriented research experience for high school students and teachers, introduce students to a potential career path in biomedical science, extablish relationships with local high school science teachers that See details	National Institutes of Health	7/17/2009
BAYLOR RESEARCH INSTITUTE, THE	$156,000	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection represents a significant global health-care problem, which is forecasted to become worse in the coming years. In the developed world, infection with HCV is responsible for 50-75% of al See details	National Institutes of Health	5/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$155,568	Trans-NIH Recovery Act Research Support By some estimates, 50% of the 56,000 US colo-rectal cancer (CRC) deaths per year in the US could be prevented by appropriate, risk-based CRC testing. Hispanics have lower incidence and mortality from CRC, but are typically diagnosed at later stages and h See details	National Institutes of Health	9/09/2009
TEXAS HEALTH RESOURCES	$153,000	ARRA - Health Information Technology Extension Program This program provides grants for the establishment of Health Information Technology Regional Extension Centers that will offer technical assistance, guidance, and information on best practices to support and accelerate health care providers? effoforts to be... Show more This spending item is part of a $9,418,318 allocation. See details	Health and Human Services, Department of	4/06/2010
COMMUNITY COUNCIL OF GREATER DALLAS INC	$150,720	Aging Home-Delivered Nutrition Services for States ARRA provided funding for Home-Delivered Nutrition Services. Established in 1978 under the Older Americans Act, the program provides meals to seniors who are homebound. This spending item is part of a $1,975,245 allocation. See details	Administration on Aging	3/18/2009
UNIVERSITY OF TEXAS AT DALLAS	$150,000	Trans-NIH Recovery Act Research Support Cochlear implant technology has developed consistently and rapidly, since auditory prostheses first came into widespread use about twenty years ago. Nowadays, cochlear implant devices can guarantee that even profoundly deaf people can enjoy hearing sensat See details	National Institutes of Health	5/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$148,432	Trans-NIH Recovery Act Research Support The essential contribution of the secreted Hedgehog signaling molecules to embryonic development and tissue homeostasis in post-embryonic animals is well established. Frequently misactivation of the Hh signal transduction pathway results in cancer. The See details	National Institutes of Health	12/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$140,542	Trans-NIH Recovery Act Research Support Haemophilus ducreyi is the etiologic agent of chancroid, a sexually transmitted genital ulcer disease. Very little is known about how this unencapsulated, Gram-negative bacterium evades host defenses and causes dermal lesion development. However, it has b See details	National Institutes of Health	9/07/2010
UNIVERSITY OF TEXAS AT DALLAS	$138,754	Trans-NIH Recovery Act Research Support Traumatic brain injury (TBI) is the number one cause of acquired long term disability with the highest rates occurring during adolescence. Despite evidence that higher order cognitive abilities may worsen or fail to adequately develop years after the brai See details	National Institutes of Health	9/01/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$138,670	Trans-NIH Recovery Act Research Support Intravenous (IV) administration of tissue plasminogen activator (tPA) is an effective and approved therapy for acute stroke when treatment is begun within 3 hours of symptom onset. Recent data suggest limited benefits up to 4.5 hours after symptom onset This spending item is part of a $3,067,107 allocation. See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$137,758	Trans-NIH Recovery Act Research Support The cell biology pathway of autophagy is emerging as both an important mechanism of tumor suppression and an important mechanism of tumor cell survival. An important controversy in the cancer field is whether autophagy should be turned on or turned off i See details	National Institutes of Health	9/01/2009
UNIVERSITY OF TEXAS AT DALLAS	$135,596	Trans-NIH Recovery Act Research Support The broad, long-term objective of this proposal is to elucidate the molecular mechanisms governing oxygen sensing, heme signaling and chaperone action in eukaryotes. Oxygen is vital for maintaining critical cellular functions in many living organisms, and See details	National Institutes of Health	8/31/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$123,366	Trans-NIH Recovery Act Research Support The broad, long-term objectives of this project are to gain novel knowledge about a highly specialized calcium (Ca2+) channel - the inositol (1,4,5)-trisphosphate receptor (InsP3R). The proposed studies are fundamental to understanding Ca2+ signaling and See details	National Institutes of Health	8/14/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$115,649	Trans-NIH Recovery Act Research Support The parent grant proposes to determine the molecular mechanism of adenylyl cyclase VII (AC7) regulation by the G13 pathway and to determine the physiological functions of AC7 in the immune system. Results from these studies in the long run will help ident See details	National Institutes of Health	8/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$112,693	Trans-NIH Recovery Act Research Support The proposed research focuses on the development of highly cancer-specific, ultra-sensitive nanoprobes for MR imaging of breast tumors. These nanoprobes have the potential to provide early detection of breast cancer for timely intervention of this dreadf See details	National Institutes of Health	7/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$109,900	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Cell signaling mediated by the Hedgehog (Hh) family of secreted proteins plays crucial roles in animal development and human diseases. The Hh pathway is operating in a similar way among organisms ranging from insects t See details	National Institutes of Health	1/08/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$109,080	Trans-NIH Recovery Act Research Support The molecular mechanisms of gamete fusion remain poorly understood in most organisms. Currently, Chlamydomonas is the only organism in which two proteins have been shown by gene disruption to be essential for the membrane fusion reaction. Our ability to See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$105,940	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): A major signaling paradigm for modulation of hormonal and other extracellular stimuli is the use heterotrimeric G proteins by cell surface receptors. Besides direct regulation of intracellular enzymes that produce seco See details	National Institutes of Health	6/18/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$105,064	Trans-NIH Recovery Act Research Support Phosphate homeostasis is maintained primarily by a bone-kidney endocrine axis. When phosphate is in excess, fibroblast growth factor-23 (FGF23) is secreted from bone and acts on kidney to promote phosphate excretion into urine, thereby inducing negative p See details	National Institutes of Health	9/04/2009
M I ESCUELITA PRESCHOOL INC	$104,627	ARRA - Head Start Grant was awarded to fund a temporary cost-of-living adjustment (COLA) increase for both Head Start and Early Head Start employees; provide quality improvement funds to improve compensation and qualifications/skills of educational personnel including thos This spending item is part of a $2,234,481 allocation. See details	Administration for Children and Families	6/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$104,505	Trans-NIH Recovery Act Research Support The long term goal of this research is to comprehensively understand the mechanisms and regulation of intracellular protein. Protein degradation regulates nearly every aspect of normal cellular function. Dysfunction of protein degradation underlies many See details	National Institutes of Health	12/22/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$100,732	Trans-NIH Recovery Act Research Support Progress in biomedical research and its translation into clinical practice require the integration of data across multiple scales (molecules, cells, organisms), organism types, and fields of research. The need for data integration is especially acute in i See details	National Institutes of Health	4/29/2011
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$100,000	Trans-NIH Recovery Act Research Support This award will provide resources to pursue further research in understanding human autoimmune diseases and will allow mentoring of physician-scientists at various stages of their careers in this area of research. The studies conducted will dissect out h See details	National Institutes of Health	9/02/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$100,000	Trans-NIH Recovery Act Research Support Quantifying the extent of interactions between different PDK isoforms and the inner lipoyl-bearing domain and between PDK4 and novel PDK4 specific inhibitors. These experiments are designed to corroborate the proposed allosteric model for the regulation See details	National Institutes of Health	12/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$100,000	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The intertwined epidemics of obesity and diabetes have produced a public health crisis that demands an improved understanding of fat biology and metabolism. Through genetic screens in C. elegans and D. melanogaster, we See details	National Institutes of Health	6/02/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$99,875	Trans-NIH Recovery Act Research Support This award is for equipment to purchase feeding cages, BioTek Synergy MX plate reader and Column Screening Kit. These equipment are requested for mouse phenotyping. See details	National Institutes of Health	2/01/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$99,442	Trans-NIH Recovery Act Research Support Project Narrative. Obesity and type 2 diabetes affect millions of people and are the cause of major health problems in the United States. To prevent and develop more effective treatments against these pathologies, a better understanding of the basic mecha See details	National Institutes of Health	12/16/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$98,925	Trans-NIH Recovery Act Research Support Produce and purify the modified tRNA reagent utilized to identify novel protein interactions with CFTR as outlined in Aim 3 of the parent Grant. See details	National Institutes of Health	12/28/2009
AMERICAN LUNG ASSOCIATION OF THE CENTRAL STATES	$98,692	ARRA - Prevention and Wellness--Communities Putting Prevention to Work MEDIA Objective 1: By December 2011, develop hard-hitting counter marketing media campaign to target high risk youth. G?? Secure media contractor G?? Select youth input and youth-driven products Anticipated Outcomes G?? Reducuce youth initiation of tob... Show more This spending item is part of a $7,593,110 allocation. See details	Centers for Disease Control and Prevention	3/18/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$98,460	Trans-NIH Recovery Act Research Support The Filo, Ebola and Marburg viruses (EBOV and MARV), are NIAD category A viruses associated with outbreaks of severe viral hemorrhagic fever. FDA-approved drugs for prophylaxis or treatment of these infections are currently lacking. This project will de This spending item is part of a $677,475 allocation. See details	National Institutes of Health	6/30/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$98,440	Trans-NIH Recovery Act Research Support The increasing incidence of obesity is a major health issue facing the USA. Moreover, the mechanisms underlying anorexia nervosa remain poorly understood. Fortunately, in the past decade several key hormones and CMS pathways controlling body weight and gl See details	National Institutes of Health	1/14/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$97,941	Trans-NIH Recovery Act Research Support Principal Investigator/Program Director (Last, first, middle): Burgess, Shawn, C RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? m Yes l No 1.a. If YES to Human Subjects Is the IRB review Pending? m Yes m No IRB Approval Dat See details	National Institutes of Health	1/25/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$94,200	Trans-NIH Recovery Act Research Support The purpose of this grant is to study the regulation of the ocular surface immune response to desiccating stress.Sj+?grenG??s syndrome causes profound dysfunction of the lacrimal functional unit (LFU) that results in decreased secretion of tear fluid and This spending item is part of a $782,975 allocation. See details	National Institutes of Health	7/20/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$94,200	Trans-NIH Recovery Act Research Support A significant potential exists to modify the structure and function of the aging human brain given intensive mental stimulation and physical activity. Age-related cognitive decline has consistently been identified on frontal lobe measures of executive con This spending item is part of a $1,000,000 allocation. See details	National Institutes of Health	9/22/2009
CHILDCAREGROUP	$92,761	ARRA - Head Start Grant for Early Head Start program under the ARRA Act. Grant amounts: COLA = $27,911. QI = $64,850. The awards provided for a Cost of Living Adjustment and Quality Improvement Funding consistent with the provisions of Section 640(a) (5) of the Head Star See details	Administration for Children and Families	6/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$92,600	Trans-NIH Recovery Act Research Support The purpose of this Recovery Act Administrative Supplement is to accelerate the pace of research on the parent NIH grant 5R01DK042921-17 entitled ?Regulation of Kidney-Specific Gene Expression.? The goal of the parent grant is to understand the roles of t See details	National Institutes of Health	12/07/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$90,500	Trans-NIH Recovery Act Research Support We continue our efforts to recruit additional pedigrees with various types of genetic lipodystrophies to ascertain those which are not linked to the known loci. These include pedigrees with congenital generalized lipodystrophy familial partial lipodystrop See details	National Institutes of Health	12/26/2009
BAYLOR RESEARCH INSTITUTE, THE	$90,000	ARRA - Strategic Health IT Advanced Research Projects (SHARP) This Strategic Health IT Advanced Research Projects (SHARP) Program seeks to support improvements in the quality, safety and efficiency of health care through advanced information technology. This spending item is part of a $15,000,000 allocation. See details	Health and Human Services, Department of	3/19/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$85,000	Trans-NIH Recovery Act Research Support In this proposal, we focus on the mechanisms of assembly and disassembly of mitotic checkpoint complex (MCC). See details	National Institutes of Health	8/13/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$83,989	Trans-NIH Recovery Act Research Support Fibrous connective tissue provides mechanical support and frameworks for the other tissues of the body. Type 1 collagen is the major protein component of fibrous connective tissue. Fibroblasts are the cell type primarily responsible for collagen biosynthe See details	National Institutes of Health	1/21/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$82,270	Trans-NIH Recovery Act Research Support Fragile X Syndrome (FXS) is the most common inherited form of mental retardation and is caused by loss of function mutations in the Fragile X Mental Retardation gene (FMR1). Patients with FXS as well as other forms of mental retardation have an excess of See details	National Institutes of Health	9/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$81,640	Trans-NIH Recovery Act Research Support The renal potassium channel ROMK is important for potassium secretion in distal renal tubles. Dysregulation of ROMK leads to abnormal blood potassium levels, which are potentially life-threatening. Studies on regulation of ROMK channels will help unders See details	National Institutes of Health	8/20/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$80,751	Trans-NIH Recovery Act Research Support PROJECT NARRATIVE Obesity, sequelae of which include diabetes mellitus and cardiovascular disease, is a major public health challenge. A better understanding of the molecular physiology of energy balance is critical to the development of effective therape See details	National Institutes of Health	12/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$80,204	Trans-NIH Recovery Act Research Support Accelerate the in vitro experiments of Specific Aim III. Use microarray techniques to analyze mRNA expression by freshly isolated TLR4 sufficient versus deficient endothelia and tubules from ischemic kidneys. See details	National Institutes of Health	12/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$80,000	Trans-NIH Recovery Act Research Support GM078163-Molecular Mechanism of Small RNA-induced RNA Silencing: A supplementary equipment grant for purchasing the ?AKTA-micro? machine from GE. A small portion ($15,000-20,000) of the supplement will be used to purchase a 4 degree cooler to house the ? See details	National Institutes of Health	8/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$80,000	Trans-NIH Recovery Act Research Support Since AscI1 is critical in transitioning cells from a progenitor state to a differentiated state, studies of the regulation of AscI1 hold significance for their fundamental contributions to multiple areas of concern to public health such as 1) manipulatio See details	National Institutes of Health	9/24/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$78,860	Trans-NIH Recovery Act Research Support The long-term goal of this project is to understand the molecular basis of inherited metabolic diseases caused by inborn errors of macromolecular catalytic machines. The model system under study is a family of highly conserved human alpha-ketoacid dehydro See details	National Institutes of Health	3/22/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$76,825	Trans-NIH Recovery Act Research Support Aberrant Ca2+ influx by SOCs mediate the pathological Ca2+ influx that is the nodal points in all forms of pancreatiitis. Aberrant Ca2+ influx triggers autophagy that targets digestive enzymes to the lysosomes and eventually kills the calls. We know tha See details	National Institutes of Health	9/04/2009
AMERICAN LUNG ASSOCIATION OF THE CENTRAL STATES	$76,816	ARRA - Prevention and Wellness--Communities Putting Prevention to Work MEDIA Objective 1: By December 2011, develop hard-hitting counter marketing media campaign to target high risk youth. G?? Secure media contractor G?? Select youth input and youth-driven products Anticipated Outcomes G?? Reducuce youth initiation of tob... Show more This spending item is part of a $7,593,110 allocation. See details	Centers for Disease Control and Prevention	3/18/2010
SOUTHERN METHODIST UNIVERSITY INC	$74,820	Trans-NIH Recovery Act Research Support Eleven total Yucatan Minipigs have been ordered and received. All animals underwent a course of oral antibiotics for bone-labeling. Following antibiotics, a bone biopsy procedure was performed taking core bone samples from the fourth cervical vertebral b This spending item is part of a $596,418 allocation. See details	National Institutes of Health	9/15/2009
UNIVERSITY OF TEXAS AT DALLAS	$73,631	Trans-NIH Recovery Act Research Support Although Event Related Potentials (ERPs) to visual stimuli have provided vital information concerning the underlying neuronal deficits related to many medical disorders, the nature of technology currently limits the populations of study to those who can s See details	National Institutes of Health	9/01/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$71,030	Trans-NIH Recovery Act Research Support The Role of Endogenous Cardiac Glycosides in Outcomes among African Americans with Hypertensive Kidney Disease. Chronic kidney disease (CKD) affects an estimated 19 million adults in the US and is associated with a higher risk of cardiovascular disease (C This spending item is part of a $325,504 allocation. See details	National Institutes of Health	9/11/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$69,956	Trans-NIH Recovery Act Research Support Argatroban, a thrombin inhibitor, has been studied in the setting of both coronary perfusion as well as acute ischemic stroke. Since the majority of ischemic stroke patients may not benefit from rt-PA alone, the combination of thrombolytics with anticoagu This spending item is part of a $1,096,944 allocation. See details	National Institutes of Health	9/22/2009
BAYLOR RESEARCH INSTITUTE, THE	$68,729	Trans-NIH Recovery Act Research Support This grant application addresses broad Challenge Area (04): Clinical Research and specific challenge topic 04-AI-101: Develop novel methods and address key questions in mucosal immunology. The proposal draws from strong preliminary data from our laborator This spending item is part of a $987,682 allocation. See details	National Institutes of Health	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$67,320	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The primary objective of this study is to evaluate the effectiveness of traditional total contact casts (TCC), removable cast walkers (RCW) and a modification of a RCW, termed the instant total contact cast (ITCC). TCC See details	National Institutes of Health	9/30/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$61,401	Trans-NIH Recovery Act Research Support The major goal of this one-year project is to provide a firm foundation for the mechanistic analysis of pathology development in Wilson?s disease (WD). WD is a severe human disorder of copper homeostasis. The gene mutated in WD encodes a copper-transporti This spending item is part of a $505,233 allocation. See details	National Institutes of Health	8/23/2010
ENTRUST, INC.	$60,561	Supply of Entrust products and support services See details	Program Support Center	9/28/2009
ENTRUST, INC.	$60,561	SUPPLY OF ENTRUST PRODUCTS AND SUPPORT SERVICES See details	Program Support Center	9/28/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$60,500	Trans-NIH Recovery Act Research Support Many human disorders such as cancer come about because genes are not regulated properly. One way genes are controlled is by how they are packaged. New drugs are needed to specifically alter the packaging of cancer genes. We have identified over twenty See details	National Institutes of Health	9/18/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$60,000	Trans-NIH Recovery Act Research Support We are planning to use HPLC in conjunction with mass spectrometry rather than trying to sort out all o f the phosphorylation events using radiolabels. The improved method will allow us to track natively phosphorylated MAP2K's and study their activity tow See details	National Institutes of Health	12/31/2009
CITYSQUARE	$60,000	Trans-NIH Recovery Act Research Support OAI, Inc. and its HWWT consortium will provide critical health and safety training for 1,335 newly hired and/or retrained weatherization, construction, environmental remediation and debris removal workers and contractors in Illinois, Louisiana, Maine and This spending item is part of a $482,000 allocation. See details	National Institutes of Health	9/06/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$56,580	Trans-NIH Recovery Act Research Support CD4+ T cells regulate multiple aspects of adaptive immune responses to intracellular pathogens through the secretion of pro-inflammatory cytokines. Innate cells of the immune system detect and respond to pathogens by secreting a number of innate cytokines See details	National Institutes of Health	9/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$55,288	Trans-NIH Recovery Act Research Support Campylobacter jejuni is a commensal bacterium of the gastrointestinal tracts of many animals, specifically birds. However, when C. jejuni infects the gastrointestinal tracts of humans, the bacterium often causes a mild to severe, bloody diarrheal syndrome See details	National Institutes of Health	9/20/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$54,263	Trans-NIH Recovery Act Research Support We are focused on two general areas of chemical synthesis: 1) regioselective and stereospecific metal-mediated nucleophilic addition reactions and 2) regioselective cycloaddition reactions. The purpose of the AFFA funds was to purchase two pieces of chrom See details	National Institutes of Health	8/28/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$51,873	Trans-NIH Recovery Act Research Support This award was issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. The parent grant (R01 ED013368) was awarded by NICDR/NIH for research on the Regulati See details	National Institutes of Health	6/05/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$50,836	Trans-NIH Recovery Act Research Support Our research program is toward the understanding of molecular basis of myelin regeneration and repair after injury in the central nervous system. This critical event is facilitated by specialized cells called oligodendrocytes, which insulate axons, facil See details	National Institutes of Health	9/25/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$50,000	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The immune mechanisms that underlie the pathogenesis and/or regulation of human autoimmune diseases represent a very important but significantly understudied aspect of human disease. Our understanding of autoimmunity a See details	National Institutes of Health	8/02/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$47,848	Trans-NIH Recovery Act Research Support The equipment purchased with this grant will be devoted to the aims of the grant to which this supplement applies. Specifically, in grant 5R01HD056370-02, we propose to study the electrophysiological and circuit alterations in a mouse model of Fragile X See details	National Institutes of Health	9/17/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$45,999	Trans-NIH Recovery Act Research Support This supplemental award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ANBL0931, which is a Phase III Study of Chimeric Antibody 14.18 in High-Risk Neuroblastoma. The primary objective of study ANBL09 This spending item is part of a $1,981,588 allocation. See details	National Institutes of Health	8/07/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$45,557	Trans-NIH Recovery Act Research Support Abstract this project aims to establish a Lung Cancer Mutation Consortium (LCMC) consisting of 13 institutions with a major interest in lung cancer and genomic testing of lung cancer as documented by having major NCI grants in lung cancer. The LCMC member This spending item is part of a $4,894,665 allocation. See details	National Institutes of Health	9/29/2009
M&A TECHNOLOGY, INC.	$43,700	MOBILE MEDICAL COMPUTER CARTS See details	Indian Health Service	8/20/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$43,563	Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Chronic gastroesophageal acid reflux and its sequela, Barrett's esophagus (BE), are strong risk factors for esophageal adenocarcinoma, a tumor whose frequency has increased six-fold over the past 30 years. The molecula See details	National Institutes of Health	6/22/2010
BAYLOR RESEARCH INSTITUTE, THE	$38,750	Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic: 06-AR-103, Systems Biology for Skin and Rheumatic Diseases. Psoriasis (PS) is a complex inflammatory skin disease where genetic risk factors and envir This spending item is part of a $997,798 allocation. See details	National Institutes of Health	9/25/2009
DREW SCIENTIFIC, INC.	$38,000	RECOVERY ACT /ARRA ORDER: HEMAVET 950FS MULIT SPECIES HEMATOLOGY SYSTEM See details	National Institutes of Health	9/15/2010
UNIVERSITY OF TEXAS AT DALLAS	$36,022	Trans-NIH Recovery Act Research Support A common feature of most neurological diseases is the premature and aberrant degeneration of neurons. A variety of molecules involved in the promotion or inhibition of neuronal survival have been identified. This proposal focuses on histone deacetylases ( See details	National Institutes of Health	7/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$35,663	Trans-NIH Recovery Act Research Support This two-year study will utilize a randomized design with the active interventions running for 18 months. We have 26 active US sites (27 approved sites with one having to drop out due to lack of indirect cost recovery to pay IRB costs). The 26 sites will This spending item is part of a $1,349,862 allocation. See details	National Institutes of Health	8/19/2009
UNIVERSITY OF TEXAS AT DALLAS	$35,209	Trans-NIH Recovery Act Research Support Cortical processing of sensory information plays a critical role in sensory discrimination, object recognition and memory. Cortical sensory processing has been shown to be highly dynamic, with past experience, current context and expectations shaping how This spending item is part of a $174,188 allocation. See details	National Institutes of Health	5/12/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$33,000	Trans-NIH Recovery Act Research Support Description of projects. Supplementary funds provided by the Recovery Act will be used to purchase new equipment currently unavailable in the laboratory and to hire a research assistant. As described below, this will accelerate progress on both of the Spe See details	National Institutes of Health	12/03/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$31,500	Trans-NIH Recovery Act Research Support The increased risk of developing heart disease, strokes, and diabetes with excess adipose tissue is well known; obesity is generally caused by excess caloric intake. Less well appreciated are the devastating effects on health of the lipodystrophies. In th See details	National Institutes of Health	1/29/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$31,400	Trans-NIH Recovery Act Research Support Abnormal development of the nervous system is thought to underlie many complex neurological disorders. In the past decade, research in several vertebrate organisms has shown the bHLH transcription factor Ascl1 (previously Mash1) is essential for neuronal See details	National Institutes of Health	7/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$28,723	Trans-NIH Recovery Act Research Support To accelerate our research into scientific publication ethics while simultaneously stimulating the economy by means of job creation and retention. It will also allow us to provide enriching educational experiences to young adults who are just entering th See details	National Institutes of Health	9/03/2009
PARKLAND HEALTH & HOSPITAL SYSTEM	$27,900	ARRA - Prevention and Wellness--State Territories and Pacific Islands Grant funds to carry out statewide evidence-based initiatives that support obesity prevention and nutrition strategies. Initiative includes promotion of optimal nutrition and obesity prevention by facilitiating the development andnd statewide implementation... Show more This spending item is part of a $2,797,900 allocation. See details	Centers for Disease Control and Prevention	2/06/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$25,371	Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C This spending item is part of a $750,000 allocation. See details	National Institutes of Health	8/13/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$23,942	Trans-NIH Recovery Act Research Support This application for an administrative supplement will provide internships for Americans (a High School student and two teachers) to experience diverse research investigations relating to non-invasive assessment of tumor development, progress, and respons See details	National Institutes of Health	6/01/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$22,465	Trans-NIH Recovery Act Research Support This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/ This spending item is part of a $1,405,307 allocation. See details	National Institutes of Health	8/12/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$21,984	Trans-NIH Recovery Act Research Support The goal of the current Grand Opportunity is to create a unique, multimodal transcriptional atlas of the pre- and postnatal developing human brain. This new and unique data-rich resource will integrate transcriptomic, cellular resolution histology and im This spending item is part of a $16,210,005 allocation. See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$17,584	Trans-NIH Recovery Act Research Support Our laboratory provides an excellent environment for undergraduates and high school educators/students to gain research experiences and to subsequently pursue an academic career in biomedical research. The administrative supplement will not only provide See details	National Institutes of Health	7/29/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$16,344	Trans-NIH Recovery Act Research Support Supplement to fund a high school student to work in a basic research lab for the summer. The goal was to provide a training experience for the student and to advance the aims of the parent grant which are to improve cardiovascular health. See details	National Institutes of Health	6/04/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$15,850	Trans-NIH Recovery Act Research Support This supplement will accelerate the progress of the four aims of the parent grant by adding a postdoctoral research associate, who is a leading expert in the synthesis and study of silver carbene complexes (SCCs), to the investigative team. Further a Nuc This spending item is part of a $214,877 allocation. See details	National Institutes of Health	4/16/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$15,850	Trans-NIH Recovery Act Research Support This supplement will accelerate the progress of the four aims of the parent grant by adding a postdoctoral research associate, who is a leading expert in the synthesis and study of silver carbene complexes (SCCs), to the investigative team. Further a Nuc This spending item is part of a $214,877 allocation. See details	National Institutes of Health	4/16/2010
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$15,700	Trans-NIH Recovery Act Research Support EGR receptor signaling is a key element in triggering specific cell fate decisions in developing eyes. But many of the downstream events and their finetuning in specific cell types is still poorly understood. The dAcn protein may play a critical role in See details	National Institutes of Health	7/14/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$15,700	Trans-NIH Recovery Act Research Support Mutations in three different genes (TERT, TERC, and SFTPA2) cause human pulmonary fibrosis. Recuritment of talented students to work alongside laboratory personnel will expedite the research in this field and encourage them to pursue a career in the heal See details	National Institutes of Health	6/10/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$15,700	Trans-NIH Recovery Act Research Support Mutation in the gene for the ABCA3 transporter cause a variety of lung diseases that result in either death in the immediate newborn period or chronic lung disease in children and into adulthood. We have created mouse models of the human ABCA3 mutations See details	National Institutes of Health	6/19/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$14,650	Trans-NIH Recovery Act Research Support This supplement to parent grant 3R01DE005092 funded the hiring of two full-time graduates during the summer prior to their entry into the freshman year of the DDS program at Baylor College of Dentistry. The two graduates will be able to gain short-term r See details	National Institutes of Health	6/15/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$14,650	Trans-NIH Recovery Act Research Support Tooth development requires the precise spatial and temporal coordination of programs for cell growth, differentiation, and mineralization. In a search for genes required for normal tooth morphogenesis we have studied Dentin matrix protein1 (DMP1), a non- See details	National Institutes of Health	6/02/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$14,650	Trans-NIH Recovery Act Research Support The parent greant (R01 DE019471) was awarded by NICDR/NIH for research on the Signaling Mechanisms in Early Tooth Development. This supplement provides short-term research experience for two college graduates during the summer preceding their entry into See details	National Institutes of Health	6/02/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$14,250	Trans-NIH Recovery Act Research Support Phosphoinositide metabolic pathways regulate a vast array of cellular functions, including signal transduction, cell growth and division, cytoskeletal assembly, and membrane trafficking. PI4P is the precursor in the biosynthesis of two of the most import This spending item is part of a $193,499 allocation. See details	National Institutes of Health	8/14/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$13,648	Trans-NIH Recovery Act Research Support Acquired brain injuries, such as those resulting from trauma, are among the most common causes death and long-term disability in all age groups. It is unclear whether neural stem cells are responsible for some of the limited recovery that spontaneously oc See details	National Institutes of Health	7/27/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$13,445	Trans-NIH Recovery Act Research Support This project seeks to a) quantify the nature and sources of diabetic alveolar function at rest and during exercise, b) relate changes in alveolar function to extra-pulmonary microangiopathy, and c) establish long term cohorts to examine the natural progre See details	National Institutes of Health	12/23/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$13,368	Trans-NIH Recovery Act Research Support The goals set forth for this project were designed from our continuing desire to improve the quality of biomedical literature as well as provide employment and enhancement opportunities for the very scientists who depend on such information. See details	National Institutes of Health	8/19/2009
TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH	$13,185	Trans-NIH Recovery Act Research Support The parent greant (R01 DE016059) was awarded by NICDR/NIH for research on the Sex Steroids and TMJ Pain. This supplement provides short-term research experience for two college graduates during the summer preceding their entry into the first year of the See details	National Institutes of Health	6/02/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$12,560	Trans-NIH Recovery Act Research Support The purpose of the award was two fold: first, to facilitate the goals of the parent grant, R01 HL085218 and second, to provide funding to support summer research by a high school or undergraduate student. See details	National Institutes of Health	6/02/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$6,948	Trans-NIH Recovery Act Research Support The rational design of a curative therapy must entail targeting the suppression of pathogenic Th2 cells. Given that both IFN-a and IFN-B are routinely used to treat hepatitis C and multiple sclerosis, our novel studies will lay the groundwork towards tes See details	National Institutes of Health	6/15/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$6,500	Trans-NIH Recovery Act Research Support Given the lack of information regarding short and long term consequences of skin grafting with respect to revascularization and reinnervation of the grafted skin, the primary objective of this proposal is to test the hypothesis that autonomic and non-auto This spending item is part of a $208,005 allocation. See details	National Institutes of Health	9/30/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$5,000	Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) in children is a devastating illness. The prevalence of patients aged 0 ? 19 years with ESRD has grown 32% since 1990 and the mortality rate for children with ESRD receiving dialysis therapy is between 30 and 150 times that o This spending item is part of a $525,000 allocation. See details	National Institutes of Health	9/27/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$1,700	Trans-NIH Recovery Act Research Support This proposal addresses Challenge area 7: Enhancing Clinical Trials: 07-OD(ORDR)-102 for the development of a rare disease genetic patient registry. Peripartum cardiomyopathy (PPCM) is a complication of pregnancy occurring in 1:1800 to 1:3500 births in th This spending item is part of a $999,818 allocation. See details	National Institutes of Health	9/21/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS	$0	Trans-NIH Recovery Act Research Support This award was declined. See details	National Institutes of Health	7/17/2009
BAYLOR RESEARCH INSTITUTE, THE	$0	Trans-NIH Recovery Act Research Support Vaccination represents one of the major successes of medicine as it has spared countless people from polio, tetanus and other acute infections. Yet, improved immunization strategies are needed to make vaccines for microbes that cause considerable morbidit This spending item is part of a $1,600,000 allocation. See details	National Institutes of Health	9/16/2009

Recovery Tracker

Dallas County, Texas, funds by Health and Human Services, Department of