Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Middlesex County, Mass., funds by Health and Human Services, Department of

Listing $491,041,662.05 in stimulus funds from Health and Human Services, Department of for Middlesex

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $44,859,291 Clinical studies of pandemic H1N1 vaccine Office of the Secretary of Health and Human Services 9/29/2009
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $44,859,291 To research and manufacture vaccines to aid in alieviating flu pandemics. Office of the Secretary of Health and Human Services 9/29/2009
BROAD INSTITUTE, INC., THE $30,965,067 This contract was awarded on September 24, 2010. We are providing second generation sequencing of tumor samples across numerous tumor types in support of The Cancer Genome Atlas (TCGA) project. In additional validation sequencing on mutations is also pe National Institutes of Health 9/24/2010
BROAD INSTITUTE, INC., THE $24,520,017 Trans-NIH Recovery Act Research Support We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (1) performi
This spending item is part of a $24,870,017 allocation. See details
National Institutes of Health 9/28/2009
BROAD INSTITUTE, INC., THE $23,820,017 Trans-NIH Recovery Act Research Support We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (1) performi
This spending item is part of a $24,870,017 allocation. See details
National Institutes of Health 9/28/2009
BOND BROS., INC. $12,937,782 National Center for Research Resources, Recovery Act Construction Support DESCRIPTION (provided by applicant): The Animal Resource Program at MIT represents a vital resource that is central to the various biomedical research missions of the Institute. This award provides funds to renovate and equip t... Show more
This spending item is part of a $15,000,000 allocation. See details
National Institutes of Health 1/13/2010
BROAD INSTITUTE, INC., THE $11,689,190 Trans-NIH Recovery Act Research Support This application proposes large-scale sequencing and genotyping in type 2 diabetes (T2D) case-control samples, addressing one of the major questions in human genetics: how and to what extent can insights into disease etiology be advanced by studying low f
This spending item is part of a $17,863,520 allocation. See details
National Institutes of Health 9/29/2009
LOWELL COMMUNITY HEALTH CENTER INC $9,351,067 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Facility Improvement Program grant: The purpose of this award to is to provide funding for the renovation and fit-out of a 100,000 square foot condo within an historic mill building. This building will be used to consolidate si... Show more Health Resources and Services Administration 10/19/2009
BROAD INSTITUTE, INC., THE $9,000,000 Trans-NIH Recovery Act Research Support The funds for this ARRA supplement will be used to scale up our activities in comprehensive cancer genome analysis by sequencing TCGA samples using whole genome or whole exome approaches across multiple cancer types. We are currently working with NHGRI t National Institutes of Health 9/30/2009
MA ST DEPARTMENT OF REVENUE $7,891,816 Child Support Enforcement 2010 OCSE Administration for Children and Families 11/23/2009
BROAD INSTITUTE, INC., THE $7,782,253 Trans-NIH Recovery Act Research Support This application proposes large-scale sequencing and genotyping in type 2 diabetes (T2D) case-control samples, addressing one of the major questions in human genetics: how and to what extent can insights into disease etiology be advanced by studying low f
This spending item is part of a $17,863,520 allocation. See details
National Institutes of Health 9/29/2009
BROAD INSTITUTE, INC., THE $5,404,574 Trans-NIH Recovery Act Research Support We propose to collect and analyze the first ever whole exome sequence data from patients with schizophrenia (SCZ, n > 118), bipolar disorder (BPD, n > 118) and controls (n >116). By providing the first comprehensive evaluation of coding variation in in
This spending item is part of a $6,150,000 allocation. See details
National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $4,804,686 Trans-NIH Recovery Act Research Support The 1000 Genomes Project is developing data resources and analytical methods required for the next stage of human genetics research: (a) discovering millions of novel polymorphisms with frequencies 0.5%-10%, which can then be tested for association to dis National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $4,753,886 Trans-NIH Recovery Act Research Support The genetic components of age-related disorders are of intense interest, and genome wide association studies (GWAS) are an important tool in identifying chromosomal loci that are associated with disease. Two of the major and interlinked challenges for suc National Institutes of Health 11/25/2009
MA ST DEPARTMENT OF REVENUE $4,603,331 Child Support Enforcement 2009 OCSE Administration for Children and Families 7/16/2009
BROAD INSTITUTE, INC., THE $4,504,725 Trans-NIH Recovery Act Research Support Our understanding of how cancers begin, survive and progress is rapidly expanding through advances in cancer genomics and modern cancer biology. In assembling the Target Discovery and Development Network (TDDN), the NCI has undertaken the mission of ide National Institutes of Health 9/29/2009
OUTCOME SCIENCES, INC. $4,486,794 The 'Registry of Patient Registries' task order includes five tasks: 1) Develop the registry of patient registries (RoPR) system, 2) Develop an outcome measures framework, 3) Research and write a white paper on creating an archive of expired patient regis
This spending item is part of a $4,997,998 allocation. See details
Agency for Healthcare Research and Quality 9/30/2010
GALENEA CORPORATION $4,484,789 Trans-NIH Recovery Act Research Support Schizophrenia is a debilitating psychiatric disorder that affects about 0.7% of the global population. Symptoms of schizophrenia can be grouped into three categories: positive symptoms, including hallucinations and delusions; negative symptoms, such as so National Institutes of Health 9/27/2010
NETBIO, INC. $4,279,266 Trans-NIH Recovery Act Research Support In order to protect civilian and military populations, it is critical to improve the diagnosis of NIAID Category A-C priority pathogens. More rapid, more sensitive, more specific, and more informative diagnosis than currently possible will allow earlier
This spending item is part of a $4,818,047 allocation. See details
National Institutes of Health 8/14/2009
BROAD INSTITUTE, INC., THE $4,165,764 Trans-NIH Recovery Act Research Support This collaborative application is submitted in response to RFA MH-09-171. The root causes of autism remain unknown, limiting efforts to understand disease heterogeneity, diagnose cases, and prevent and treat disease. Epidemiological findings have repeated National Institutes of Health 9/24/2009
OUTCOME SCIENCES, INC. $3,698,837 The Registry for 'Comparative Effectiveness of Treatment Strategies for Primary Open Angle Glaucoma' task order has 5 primary objectives. 1) Identify decisions under consideration by stakeholders for which available scientific evidence is insufficient to
This spending item is part of a $4,055,617 allocation. See details
Health and Human Services, Department of 7/13/2010
BRUKER BIOSPIN CORPORATION $3,650,000 850NMR Spectrometer, Avance III 700 NMR spectrometer, Avance III 600 NMR console frequency conversion National Institutes of Health 6/22/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $3,484,821 Trans-NIH Recovery Act Research Support The research in this proposal will apply genetic, cell biological and chemical screening approaches with the goal of identifying novel treatments for type 2 diabetes (T2D), thus addressing thematic areas 1 and 2 of this grants program. Due to a relative d
This spending item is part of a $4,395,697 allocation. See details
National Institutes of Health 9/23/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $3,066,436 Trans-NIH Recovery Act Research Support Elucidating the structure and function of brain circuits is arguably this century's greatest scientific challenge. Pioneering studies in invertebrates have established that this challenge can be met by combining anatomical circuit diagrams ('connectomes') National Institutes of Health 9/24/2009
IQUUM, INC. $2,999,958 Trans-NIH Recovery Act Research Support This grant provides support for the late stage development and clinical validation of the LiatTM HIV-1 Assay for quantitation of Human Immunodeficiency Virus-1 (HIV-1) in less than one hour in near-patient settings. This real-time decision making can mor National Institutes of Health 9/29/2010
SELECTA BIOSCIENCES, INC. $2,996,608 Trans-NIH Recovery Act Research Support The goal of this project is to develop a superior anti-nicotine vaccine for smoking cessation. A high incidence of smoking makes smoking-related diseases the leading cause of preventable death and morbidity. Even though 70% of smokers desire to quit and 4 National Institutes of Health 4/30/2010
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $2,980,129 Trans-NIH Recovery Act Research Support Understanding the consequences of health insurance coverage is central to evaluating proposals to expand or modify health insurance coverage in the U.S. It also has important long-run fiscal implications for Medicare. Yet there is remarkably little convi
This spending item is part of a $11,476,770 allocation. See details
National Institutes of Health 9/29/2009
INTERSYSTEMS CORPORATION $2,900,000 ARRA - State Grants to Promote Health Information Technology The purpose of the State Health Information Exchange Cooperative Agreement Program is to fund statesG?? efforts to rapidly build capacity for exchanging health information across the health care system both within and across states. As an a... Show more
This spending item is part of a $18,837,639 allocation. See details
Health and Human Services, Department of 2/08/2010
HELICOS BIOSCIENCES CORPORATION $2,773,232 Trans-NIH Recovery Act Research Support DNA sequencing technology has improved dramatically over recent years with orders of magnitude improvements in the yield of sequence data having resulted from applying massively parallel approaches. Helicos has taken next generation sequencing even furthe
This spending item is part of a $2,897,065 allocation. See details
National Institutes of Health 9/25/2009
3RD MILLENNIUM, INC. $2,645,995 The Cancer Knowledge Cloud will connect and share information generated through NCI genomic atlas projects, the caHUB tissue acquisition network, the NCI functional Biology Consortium, NCI patient Characterization Center, the NCI pre-clinical Development
This spending item is part of a $103,000,000 allocation. See details
National Institutes of Health 11/23/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $2,520,000 Trans-NIH Recovery Act Research Support Disease-causing pathogens are among the most intriguing forces shaping human evolution, as they have a tremendous impact on our genome and themselves evolve over time. A genome-wide survey of human variation indentified two genes biologically linked to L National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $2,445,408 Trans-NIH Recovery Act Research Support Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, with an incidence of about 1 in 8,000 adults. The most common form of the disease, DM1, is caused by an expanded CTG repeat in the 3' UTR of the DMPK gene, and CUG repeat R
This spending item is part of a $2,922,996 allocation. See details
National Institutes of Health 9/30/2009
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $2,189,997 Trans-NIH Recovery Act Research Support The NBER Program Project on the Economics of Aging is a coordinated set of research projects on the health and economic circumstances of individuals as they age and on the implications of population aging. Its six major themes are: work and retirement be National Institutes of Health 4/20/2010
COMMUNITY TEAMWORK,INC. $2,121,865 ARRA - Head Start This award provides for ARRA Early Head Start Expansion funded to serve 72 children and ARRA Head Start Expansion to serve 18 children. The Early Head Start and Head Start programs provide family-centered services for low-income families with young child Administration for Children and Families 9/17/2009
BROAD INSTITUTE, INC., THE $2,063,195 Trans-NIH Recovery Act Research Support The major goal of this project is to assess the associations of genetic markers with cognitive decline among older African Americans and Africans so as to identify genetic factors that are related to this problem.
This spending item is part of a $2,654,871 allocation. See details
National Institutes of Health 9/29/2009
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $2,036,565 Trans-NIH Recovery Act Research Support The NBER Program Project on the Economics of Aging is a coordinated set of research projects on the health and economic circumstances of individuals as they age and on the implications of population aging. Its six major themes are: work and retirement be
This spending item is part of a $2,189,997 allocation. See details
National Institutes of Health 4/20/2010
BROAD INSTITUTE, INC., THE $1,994,336 Trans-NIH Recovery Act Research Support Exploration with DNA chips of the genomeG??s activity holds great potential for human health. Using a combination of high-throughput genomics and computational biology, we will perform a broad exploration of gene expression in human blood cells. Distinct
This spending item is part of a $7,300,907 allocation. See details
National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $1,935,976 Trans-NIH Recovery Act Research Support The Connectivity Map 100k project aims to forge a path toward a comprehensive 'functional look-up table' that that links disease biology, genome function and small-molecule action. Such a Connectivity Map would enable researchers worldwide to generate tes National Institutes of Health 9/29/2009
IQUUM, INC. $1,872,460 Trans-NIH Recovery Act Research Support Rapid Point of Care Diagnostics Assay for Pandemic Influenza. We propose to develop a Liat(tm) Pandemic Influenza Assay to enable the specific detection and differentiation of potential pandemic influenza in less than 25 minutes. We will also develop a National Institutes of Health 9/11/2009
IQUUM, INC. $1,872,460 Trans-NIH Recovery Act Research Support We propose to develop a Liat(tm) Avian Influenza Assay to enable the specific detection and differentiation of potential pandemic avian influenza A/H5, A/H7 and A/H9 in less than 25 minutes. We will also develop a high throughput Liat Workstation and upgr National Institutes of Health 9/11/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $1,843,136 Trans-NIH Recovery Act Research Support The mission of the Beta Cell Biology Consortium (BCBC) is to bring a team-based approach to the acquisition of new knowledge and the production of novel resources necessary to develop cell-based therapies for insulin delivery. The main research strategies
This spending item is part of a $5,239,099 allocation. See details
National Institutes of Health 9/22/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $1,840,766 Trans-NIH Recovery Act Research Support The Forsyth Institute's second century will see exciting new changes in location, research opportunities and resource availability. In 2010, Forsyth, the world leader in oral and craniofacial research will relocate to Cambridge, MA. The uncommitted growth National Institutes of Health 9/15/2009
BROAD INSTITUTE, INC., THE $1,830,757 Trans-NIH Recovery Act Research Support The lack of sensitive, specific, multiplex-able assays for most human proteins is a major technical barrier that impedes progress in the biomedical sciences by prohibiting hypothesis testing in quantitative proteomics, where relationships between protein
This spending item is part of a $4,800,000 allocation. See details
National Institutes of Health 9/30/2009
ABT ASSOCIATES INC. $1,827,164 This Task Order serves the following functions of support to a program of R24 (Infrastructure Development) and R21 (Preliminary Research, in 2008 and 2010) grantees directed at Patient Centered Outcomes Research on complex patient populations: - Creation
This spending item is part of a $2,927,937 allocation. See details
Agency for Healthcare Research and Quality 9/27/2010
BROAD INSTITUTE, INC., THE $1,764,464 Trans-NIH Recovery Act Research Support Most human tumors, particularly those derived from epithelial cancers, exhibit global genomic alterations that make it difficult to identify mutations critical for cell transformation and to define the consequences of specific cancer-associated mutations.
This spending item is part of a $5,996,302 allocation. See details
National Institutes of Health 9/29/2009
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $1,726,658 Funds to purchase Pediatric Influenza Vaccine Centers for Disease Control and Prevention 6/08/2009
BROAD INSTITUTE, INC., THE $1,693,675 Trans-NIH Recovery Act Research Support This competitive supplement application proposes a genome wide association study to engage in discovery to identify potential novel pathways explanatory of the progression of renal disease.
This spending item is part of a $2,100,000 allocation. See details
National Institutes of Health 9/29/2009
INSTITUTE FOR HEALTHCARE IMPROVEMENT $1,655,563 BAH will provide technical assistance to the Beacon Community Cooperative Agreement awardees and ONC as together they lead the development of a regional healthcare strategy for Health Information Technology (HIT) ?enabled cost and quality performance impr
This spending item is part of a $11,933,252 allocation. See details
Program Support Center 9/30/2010
FORSYTH DENTAL INFIRMARY FOR CHILDREN $1,557,486 National Center for Research Resources, Recovery Act Construction Support The Forsyth Institute, the world's leader in oral and craniofacial disease research, requests $3.79 million to renovate 8,935 ft2 of space for laboratory, core facility, office and clinical research use to create a new interdis... Show more National Institutes of Health 2/25/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,544,000 Trans-NIH Recovery Act Research Support This application was submitted by the David H. Koch Institute for Integrative Cancer Research at MIT (Kl), which succeeded the MIT Center for Cancer Research (CCR) in 2007. Funds were requested to hire an MD/PhD physician-scientist. Dr. Matthew Vander Hei National Institutes of Health 9/29/2009
CHILD DEVELOPMENT AND EDUCATION, INC. $1,537,083 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
VISTA SCIENTIFIC LLC $1,524,601 Trans-NIH Recovery Act Research Support Title: Ocular Insert for Non-Invasive Sustained Drug Delivery for the Treatment of Glaucoma. Through Phase I and Phase II SBIR Grant Awards, Vista Scientific has developed and combined two unique drug delivery technologies that can resolve several ophth
This spending item is part of a $1,604,601 allocation. See details
National Institutes of Health 9/16/2009
BROAD INSTITUTE, INC., THE $1,490,517 Trans-NIH Recovery Act Research Support We will conduct a genome-wide scan on an Illumina 610k platform for colorectal cancer in the following well characterized study populations: The Women's Health Initiative (WHI), the Nurses' Health Study (NHS), the Physician's Health Study, (PHS), and the
This spending item is part of a $4,609,171 allocation. See details
National Institutes of Health 9/29/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,473,757 Trans-NIH Recovery Act Research Support The specific aims of this Phase 1 of a 2-Phase program to design, manufacture, and operate a prototype 200MHz/38mm 'bench-top' NMR 'annulus' magnet (in Phase 2: 300MHz/43mm and 500MHz/43mm magnets) are four-fold: 1) Design, manufacture, and operation of a National Institutes of Health 6/05/2009
BIOSENSE TECHNOLOGIES, INC. $1,443,687 Trans-NIH Recovery Act Research Support Platelet transfusion is the leading cause of transfusion related bacterial sepsis. Despite the mandated testing of platelet concentrate (PC) for contaminant bacteria, limitations in currently used testing methods continue to result in a significant number
This spending item is part of a $1,998,687 allocation. See details
National Institutes of Health 6/10/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,415,803 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Two photon excitation offers significant advantages over other types of microscopy-based imaging, especially for imaging living cells either in vivo or in thick slices. Indeed, the technology underlying two photon imag National Institutes of Health 5/13/2010
ABT ASSOCIATES INC. $1,379,567 Trans-NIH Recovery Act Research Support This funded project aims to develop and implement an ongoing Rx Drug Diversion Surveillance Program that will provide epidemiological data at the national and sub-national levels for 2008. The principal aim will be to estimate the diversion from retail p National Institutes of Health 9/25/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $1,356,449 Trans-NIH Recovery Act Research Support The Forsyth Institute, the world's leader in oral and craniofacial disease research, requests funds to renovate 606 ft2 for a new state-of-the-art data center core at its new research facility at 245 First Street, Cambridge, MA. The data center will suppo National Institutes of Health 4/01/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,328,669 Trans-NIH Recovery Act Research Support The proposed research is focused on the development of high frequency dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) as an approach to enhance sensitivity in solid state and solution NMR based structural biology experiments. In additi National Institutes of Health 7/15/2009
RADIATION MONITORING DEVICES, INC. $1,318,815 Trans-NIH Recovery Act Research Support SBIR Award National Institutes of Health 8/28/2009
ABT ASSOCIATES INC. $1,316,563 Development, Maintenance and Support of Hospital Clinical Quality Measures for ARRA HITECH - Over the three-year project, Abt will create quality measures. The firm will aslo test and validate the measures. In addition, Abt will perform environmental scan
This spending item is part of a $4,899,123 allocation. See details
Health Care Financing Admin. (was Medicare and Medicaid Serv.) 7/18/2011
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $1,313,049 Trans-NIH Recovery Act Research Support We propose to develop and improve a novel minimally-invasive retinal prosthesis design. The goal is to restore a limited but useful level of vision to patients blind with retinitis pigmentosa or macular degeneration. The implant will be driven wirelessly,
This spending item is part of a $2,270,042 allocation. See details
National Institutes of Health 6/05/2009
BOSTON COLLEGE, TRUSTEES OF $1,302,192 Trans-NIH Recovery Act Research Support Modular Software for Sequence Data Quality Checking Alignment and Variant Calling: The purpose of this project is to implement a DNA sequence processing pipeline at the National Center for Biotechnology Information (NCBI) at the NIH. This pipeline is inte
This spending item is part of a $2,249,700 allocation. See details
National Institutes of Health 9/21/2009
MCLEAN HOSPITAL CORPORATION, THE $1,279,991 Trans-NIH Recovery Act Research Support We have developed a plan for a NINDS research organization/consortium to develop, characterize and study iPS cell lines for Parkinson's disease (PD). The overall goal of this consortium of multiple- Pis (see leadership plan) is to organize the rapidly exp
This spending item is part of a $3,700,091 allocation. See details
National Institutes of Health 9/28/2009
BROAD INSTITUTE, INC., THE $1,218,671 Trans-NIH Recovery Act Research Support Next-generation sequencing produces huge amounts of data that require significant investments in computation resources and data storage to convert sequencing instrument output into biomedical knowledge. Such large data center investments can prove to be National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $1,217,186 Trans-NIH Recovery Act Research Support The lack of sensitive, specific, multiplex-able assays for most human proteins is a major technical barrier that impedes progress in the biomedical sciences by prohibiting hypothesis testing in quantitative proteomics, where relationships between protein
This spending item is part of a $4,800,000 allocation. See details
National Institutes of Health 9/30/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $1,209,000 Trans-NIH Recovery Act Research Support Abstract This application is in response to Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4). In particular we are responding to (Theme 1) Applying Genomics and Other High Throughput Technologies and (
This spending item is part of a $4,585,020 allocation. See details
National Institutes of Health 9/01/2010
MCLEAN HOSPITAL CORPORATION, THE $1,176,141 Trans-NIH Recovery Act Research Support The limited supply of red blood cells (RBC) and platelets is a serious medical issue that can have life-threatening consequences for transfusion-dependent patients, particularly those who develop platelet allo-immunity. The low prevalence of O Rh-negative
This spending item is part of a $1,896,390 allocation. See details
National Institutes of Health 9/20/2010
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $1,153,892 Trans-NIH Recovery Act Research Support The overall purpose of this award is to determine the role of Mdm2 and its homolog Mdm4 in maladaptive cardiac hypertrophy and the associated apoptosis. Mdm2 is an E3 ubiquitin ligase, which promotes the proteasome-mediated degradation of the tumor suppr National Institutes of Health 8/14/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $1,119,387 Trans-NIH Recovery Act Research Support The prevalence of fluorosis among the population is increasing yet we currently know very little about what causes fluorosis. We have previously demonstrated that fluoride elicits a cell stress response which in turn, activates genes to help the cell cope
This spending item is part of a $1,142,778 allocation. See details
National Institutes of Health 4/29/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $1,101,539 Trans-NIH Recovery Act Research Support The overall goal of this study is to understand the mechanism underlying transcription factors specifying osteoclast lineage commitment and differentiation. This proposal is highly significant since elucidating osteoclast lineage commitment and differenti National Institutes of Health 9/01/2009
INSTITUTE FOR HEALTHCARE IMPROVEMENT $1,072,597 ARRA Accelerating Adoption of Comparative Effectiveness Research (CER) Recent comparative effectiveness research has identified three interventions that substantially reduce SSIs: preoperative bathing or showering with chlorhexidine; preoperative nasal screening for Staphylococcus aureus carriage fol... Show more
This spending item is part of a $2,794,876 allocation. See details
National Institutes of Health 9/20/2010
ARCADIA SOLUTIONS LLC $1,071,000 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
GALENEA CORPORATION $1,063,611 Trans-NIH Recovery Act Research Support Schizophrenia is a devastating mental illness that affects approximately 1% of the global population. Symptoms of schizophrenia can be grouped into three categories: positive symptoms, such as hallucinations; negative symptoms, such as social isolation a National Institutes of Health 9/30/2009
NEWTON PHOTONICS INC $1,004,618 Trans-NIH Recovery Act Research Support The sensor will be used in diagnostic laboratories and public health facilities. It will mitigate the effect of a biological attack by providing early detection and verification of intoxication by botulinum and many othe biological agents. National Institutes of Health 9/01/2009
MCLEAN HOSPITAL CORPORATION, THE $1,000,000 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area 03: Biomarker Discovery and Validation, and the specific Challenge Topic 03-MH-101: Biomarkers in Mental Disorders. Attention-deficit/hyperactivity disorder (ADHD) is the most prevalent behavioral disorder o National Institutes of Health 9/29/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $999,997 Trans-NIH Recovery Act Research Support This application addresses broad challenge area (14) Stem Cells and the specific challenge topic 14-EB-101 Synthetic Delivery Systems for Generating Pluripotent Stem Cells The recent advent of cell reprogramming as a means of producing induced pluripotent National Institutes of Health 9/23/2009
BROAD INSTITUTE, INC., THE $998,425 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic 08-DK-106 : Genomics of complex diseases. The innate immune system is the first-line of defense against harmful bacteria and viruses. It senses foreign invaders th National Institutes of Health 9/29/2009
SMITHSONIAN INSTITUTION $990,443 Trans-NIH Recovery Act Research Support We have developed a prototype x-ray microanalysis system with unprecedented spatial and spectroscopic resolution. It combines two state-of-the-art instruments. One is a cryogenic x-ray microcalorimeter that we built several years ago for x-ray astronomy m National Institutes of Health 9/29/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $979,405 Trans-NIH Recovery Act Research Support To derive induced pluripotent stem cells from donated peripheral blood. We have made substantial progress with this project goal, We have been able to generate iPS cells from human fresh and frozen peripheral blood (Staerck et al 2010). Because blood i National Institutes of Health 8/27/2010
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $975,000 Trans-NIH Recovery Act Research Support The aims of this proposal for supplementary funding are to complete the sequencing and annotation of four chromosomes G?? the mouse, rhesus, and bull Y chromosomes and the chicken Z chromosome G?? within two years. These chromosomes represent half of the National Institutes of Health 9/18/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $974,549 Trans-NIH Recovery Act Research Support Recovery Act Limited Competition: NIH Challenge Grants in Health and Science Research (RC1) RFA-OD-09-003 Broad Challenge Area: 15, Translational Science Research Area: 15-MH-109 Prefrontal cortex regulation of higher brain function and complex behaviors. National Institutes of Health 9/22/2009
LOWELL COMMUNITY HEALTH CENTER INC $970,755 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Program -The purpose of this award is to provide funding for the renovation of space in the Metta Health Center of Lowell Community Health Center. This renovation will result in the addition of exam room and behavi... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF MASSACHUSETTS $968,410 Trans-NIH Recovery Act Research Support Translational Research: From Mechanisms of Influenza Trnasmission to Prevention National Institutes of Health 9/25/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $963,964 Trans-NIH Recovery Act Research Support NIH Broad Challenge Area 15 - Translational Science NIMH Specific Challenge Topic 15-MH-109 - Prefrontal cortex regulation of higher brain function and complex behaviors. Abstraction is the ability to detect and store the commonalities across experiences National Institutes of Health 9/30/2009
TRUSTEES OF TUFTS COLLEGE INC $923,663 Trans-NIH Recovery Act Research Support Although small-scale studies have evaluated oral disease in the developmentally disabled, the oral health status, treatment needs and helpful interventions for adults with developmental disabilities (DD) are largely unknown. The inability of many adults w National Institutes of Health 9/17/2009
APHIOS CORPORATION $920,464 Trans-NIH Recovery Act Research Support This project entitled ?CFI Pathogen Inactivation Technology,? is in response to the challenge of developing Enabling Technologies to ?Ensure a safe and adequate blood supply through the development of new processing technologies.? There are a number of em National Institutes of Health 9/21/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $919,338 Trans-NIH Recovery Act Research Support Despite many studies that have aimed to alleviate the effects of periodontal and endodontic disease there is still an urgent need to improve the oral health of those suffering from oral infectious or inflammatory diseases. Such translational application o National Institutes of Health 9/22/2009
HEPREGEN $910,000 Trans-NIH Recovery Act Research Support Animal studies are insufficient for predicting human liver responses due to significant species-specific differences in liver functions. Therefore, a plethora of in vitro human liver models have been developed over the last three decades to supplement tes National Institutes of Health 9/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $902,969 Trans-NIH Recovery Act Research Support The long-term goal of this research is a fundamental understanding of how the eye communicates with the brain. More immediately, the research serves to validate and improve a set of genetic tools for the study of neural circuits. The retina is a complex n National Institutes of Health 9/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $900,485 Trans-NIH Recovery Act Research Support The goal of this project is to generate evidence-based measures of the effectiveness of 65 federally-funded teacher professional development institutes for middle school life science teachers. Such institutes typically meet for a week or longer during sum National Institutes of Health 9/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $894,598 Trans-NIH Recovery Act Research Support Brain function depends critically on the normal operation of synapses and their capacity for modification. An understanding the basic properties of synaptic transmission and plasticity is necessary for illuminating the mechanisms of synaptic dysfunction i National Institutes of Health 7/17/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $874,000 Trans-NIH Recovery Act Research Support Orthopoxviruses (Smallpox, Monkeypox, etc.) have the potential for causing serious human health problems. Although Smallpox has been eradicated from the wild, it is feared that there may be rogue stockpiles that have the potential to be used as weapons o
This spending item is part of a $2,365,512 allocation. See details
National Institutes of Health 8/01/2009
BRANDEIS UNIVERSITY $870,812 Trans-NIH Recovery Act Research Support Brandeis University is home to 22 neuroscience research laboratories and is a rich and collaborative environment for neuroscience research. However, a gap exists between cellular and molecular neuroscientists using mainly in vitro techniques, and the syst National Institutes of Health 9/25/2009
INSTITUTE FOR HEALTHCARE IMPROVEMENT $866,600 The purpose of the award is to support the Office of the National Coordinator for Health Information Technology (ONC) to plan, implement, maintain and evaluate performance of a collaborative Knowledge Sharing Network (KSN) for the Health information Techn
This spending item is part of a $10,682,420 allocation. See details
Agency for Healthcare Research and Quality 3/31/2010
BRANDEIS UNIVERSITY $858,452 Trans-NIH Recovery Act Research Support CaMKII is the most abundant kinase in neurons and is highly concentrated at synapses. The kinase has switch-like on/off properties that are activated during LTP induction. Mutations that interfere with this switching produce strong deficits in LTP and mem
This spending item is part of a $933,452 allocation. See details
National Institutes of Health 7/17/2009
MASSACHUSETTS PEER REVIEW ORGANIZATION, INC. $852,738 Booz Allen will support the Office of the National Coordinator for Health Information Technology (ONC) and it Health Information Technology Research Center (HITRC) to plan, coordinate, and facilitate the training of staff in Regional Exchange Centers (REC
This spending item is part of a $9,198,119 allocation. See details
Agency for Healthcare Research and Quality 3/31/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $851,691 Trans-NIH Recovery Act Research Support This application addresses Broad Challenge Area (12) Science, Technology, Engineering and Mathematics Education and Specific Challenge Topic 12-OD-104 Innovative approaches to STEM education Project Summary/Abstract This proposal outlines research on usin National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $847,500 Trans-NIH Recovery Act Research Support The Broad Institute performs high-throughput large scale biology with academic collaborators from across the country, investigating a wide variety of biological systems. In this proposal the Broad Institute core small molecule screening group is requestin National Institutes of Health 7/15/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $826,163 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (14) Stem Cells and specific Challenge Topic, 14-DE-103: Enhancing Human Embryonic Stem (ES) Cell Culture Systems. The overall objective of this proposal is to develop and optimize a feeder-free in vitro cul
This spending item is part of a $975,069 allocation. See details
National Institutes of Health 3/09/2010
COMMUNITY TEAMWORK,INC. $824,091 ARRA - Community Services Block Grant The Community Services Block Grant program improves the economic and social well-being of low-income individuals and families of the Commonwealth. The overall objective of the CSBG-ARRA program is to assist low-income residents in becoming economically
This spending item is part of a $24,922,586 allocation. See details
Administration for Children and Families 4/10/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $820,069 Trans-NIH Recovery Act Research Support The longterm goal of our research program is to elucidate the complex neural processing of chemical and mechanical respiratory afferent inputs that underlie the control of breathing by brainstem nuclei in health and in cardiopulmonary diseases. In the pas
This spending item is part of a $840,000 allocation. See details
National Institutes of Health 8/31/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $812,391 Trans-NIH Recovery Act Research Support Somatic reprogramming efforts have focused on using embryonic stem (ES) cells and their differentiated progeny to regenerate various adult tissues depleted by aging or by various pathological processes. Alternatively, this goal might be reached via experi National Institutes of Health 9/22/2009
CHILD CARE RESOURCE CENTER INC $808,470 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
BROAD INSTITUTE, INC., THE $804,338 Trans-NIH Recovery Act Research Support The 1000 Genomes Project is developing data resources and analytical methods required for the next stage of human genetics research: (a) discovering millions of novel polymorphisms with frequencies 0.5%-10%, which can then be tested for association to dis National Institutes of Health 9/30/2009
MASSACHUSETTS EHEALTH COLLABORATIVE, INC $800,000 ARRA - State Grants to Promote Health Information Technology New Hampshire Health Information Exchange Planning and Implementation Project: to promote the assessment and implementation of Health Information Exchange in the State of New Hampshire through the collaboration with the Health Care Communit... Show more
This spending item is part of a $5,457,856 allocation. See details
Health and Human Services, Department of 2/08/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $789,401 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic, 08-OD-101, Computational approaches for epigenomic analysis. While the primary DNA sequence of the human genome is ultimately responsible for the encoding and fun
This spending item is part of a $939,401 allocation. See details
National Institutes of Health 9/21/2009
BRANDEIS UNIVERSITY $787,100 Trans-NIH Recovery Act Research Support The sympathetic nervous system innervates a number of targets, including the heart, and sympathetic activity is a critical regulator of cardiac function. Sympathetic neurons form noradrenergic synapses onto heart cells resulting in excitation of myocyte f National Institutes of Health 7/15/2009
CAMBRIDGE PUBLIC HEALTH COMMISSION $785,872 Trans-NIH Recovery Act Research Support This application provides the opportunity to fill the knowledge gap of Comparative Effectiveness Research (CER) for mental health care for Latinos by comparing two public health approaches. One is offered by telephone and one face-to face, consisting of a
This spending item is part of a $1,400,000 allocation. See details
National Institutes of Health 9/18/2010
BOSTON COLLEGE, TRUSTEES OF $782,500 Trans-NIH Recovery Act Research Support Glucose Energy Metabolism in the Growth and Survival of B Lymphocytes: Lymphocytes use considerable amounts of energy to maintain both housekeeping functions and to support growth and effector functions in response to antigen (Ag) challenge. Changes i National Institutes of Health 5/14/2009
BRANDEIS UNIVERSITY $782,187 Trans-NIH Recovery Act Research Support Reaching for objects is a natural and common behavior. A great deal of behavioral and physiological effort has been devoted to understanding reaching behavior. This project is the continuation of a unique attempt to understand how humans are able to reach National Institutes of Health 8/13/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $781,967 Trans-NIH Recovery Act Research Support The aims of the ENCODE (Encyclopedia of DNA Elements) and modENCODE (model organism ENCODE) projects are to apply high-throughput, cost-efficient approaches to generate a catalog of functional elements in the human, worm, and fly genomes, which will serve
This spending item is part of a $2,789,724 allocation. See details
National Institutes of Health 9/30/2009
BEDFORD VA RESEARCH CORPORATION, INC., THE $778,702 Trans-NIH Recovery Act Research Support Parkinson?s Disease (PD) as well as other neurodegenerative diseases are associated with oxidative damage. In PD, there is an early reduction in reduced glutathione in the substantia nigra, as well as increases in markers of lipid, protein and DNA oxidati
This spending item is part of a $1,453,349 allocation. See details
National Institutes of Health 9/16/2009
MATTEK CORPORATION $773,701 Trans-NIH Recovery Act Research Support Psoriasis is a chronic, inflammatory, hyper-proliferative skin disease that affects nearly 80 million people worldwide. During Phase 1, cells from involved psoriatic lesions were harvested, proliferated in monolayer culture, and cryopreserved. Culture con
This spending item is part of a $871,183 allocation. See details
National Institutes of Health 9/24/2009
MASSACHUSETTS EHEALTH COLLABORATIVE, INC $763,000 ARRA - Health Information Technology Extension Program The New York eHealth Collaborative (NYeC), in partnership with the Massachusetts eHealth Collaborative (MAeHC), is pleased to submit this response to the Regional Centers Cooperative Agreement Program Funding Opportunity Announcement to establish... Show more
This spending item is part of a $27,589,318 allocation. See details
Health and Human Services, Department of 2/08/2010
TRUSTEES OF TUFTS COLLEGE INC $762,263 Trans-NIH Recovery Act Research Support The understanding of how nervous system activity gives rise to behavior and cognition is being revolutionized by experimentation with molecularly-tractable model species such as zebrafish. These efforts are greatly hampered by the lack of automation in th National Institutes of Health 8/12/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $745,195 Trans-NIH Recovery Act Research Support Title: Electronic Sequencing in Nanopores. This research will accelerate the progress made that addresses the first three closely related aims of HG003703 whose overall goal is to develop a device capable of inexpensive de novo sequencing. When fully deve National Institutes of Health 8/12/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $744,567 Trans-NIH Recovery Act Research Support A barrier to the effective delivery of cancer chemotherapy drugs is the transport of the toxic drug to specific tumor cells, ensuring high uptake of drug by cancer cells while avoiding noncancerous ones. One means of accomplishing this method is the use o National Institutes of Health 8/13/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $736,120 Trans-NIH Recovery Act Research Support The economical sequencing of a number of individual human genomes has been made possible by next-generation sequencing (NGS) methods. These same sequencing methods are now being applied to gene expression profiling. However, next-generation methods, when National Institutes of Health 9/21/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $733,014 Trans-NIH Recovery Act Research Support Our tissue engineering approach to heart muscle regeneration combines heart cells with a biodegradable polymer template (scaffold) in a laboratory culture device (bioreactor) to create a contractile heart muscle graft. Such tissue engineered cardiac graft
This spending item is part of a $1,265,929 allocation. See details
National Institutes of Health 6/01/2009
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $731,363 Funds to purchase Adult Influenza Vaccine Centers for Disease Control and Prevention 5/18/2010
TRUSTEES OF TUFTS COLLEGE INC $709,197 Trans-NIH Recovery Act Research Support Characteristics of the built environment can create/sustain health disparities, hence tackling them requires interventions to address macro-level factors that influence health. By addressing the causes of health disparites among Latino children/youth earl
This spending item is part of a $949,006 allocation. See details
National Institutes of Health 9/21/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $708,025 Trans-NIH Recovery Act Research Support The HOG pathway is a well-characterized mitogen-activated protein kinase (MAPK) cascade in yeast. MAPK pathways are evolutionary-conserved eukaryotic signaling modules that regulate diverse cellular processes including pheromone signaling, metabolism, dif National Institutes of Health 9/25/2009
INSTITUTE FOR HEALTHCARE IMPROVEMENT $703,136 The purpose of the award is to support the Office of the National Coordinator for Health Information Technology (ONC) to plan, implement, maintain and evaluate performed of a collaborative Knowledge Sharing Network (KSN) for the Health Information Technol
This spending item is part of a $10,682,420 allocation. See details
Agency for Healthcare Research and Quality 3/31/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $700,111 Trans-NIH Recovery Act Research Support This work addresses broad Challenge Area (15) Translational Science, and specific Challenge Topic Applied Translational Technology Development. Mechanical ventilation is a life support procedure that is indicated for a wide variety of acute or chronic res
This spending item is part of a $952,729 allocation. See details
National Institutes of Health 9/24/2009
CAMBRIDGE ECONOMIC OPPORTUNITY COMMITTEE, INC $698,255 ARRA - Community Services Block Grant The Community Services Block Grant program improves the economic and social well-being of low-income individuals and families of the Commonwealth. The overall objective of the CSBG-ARRA program is to assist low-income residents in becoming economically
This spending item is part of a $24,922,586 allocation. See details
Administration for Children and Families 4/10/2009
BROAD INSTITUTE, INC., THE $693,768 Trans-NIH Recovery Act Research Support Cancer is a disease of the genome. The goal of TCGA is to comprehensively characterize the cancer genome to enable 1) the elucidation of the biological bases of cancer, 2) identification of the most promising therapeutic targets, and 3) discovery of biom National Institutes of Health 9/17/2010
BRANDEIS UNIVERSITY $685,160 Trans-NIH Recovery Act Research Support Perception and memory are central to the ordinary but important activities of everyday life. When cooperative interactions between the two processes are undermined by genetic or acquired disorder, by drugs of abuse, by inattention, or by age-related chang National Institutes of Health 6/08/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $673,629 Trans-NIH Recovery Act Research Support Heparin is a sulfated polysaccharide mixture that is widely used as baseline therapy in a number of clinical situations, especially for preventing thrombosis. While heparin has been administered in the clinic for the past several decades, recently, cluste
This spending item is part of a $1,273,134 allocation. See details
National Institutes of Health 9/28/2009
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $668,704 Funds to purchase pediatric Vaccine Centers for Disease Control and Prevention 4/15/2010
TRI-CITY COMMUNITY ACTION PROGRAM INC $668,647 ARRA - Community Services Block Grant The Community Services Block Grant program improves the economic and social well-being of low-income individuals and families of the Commonwealth. The overall objective of the CSBG-ARRA program is to assist low-income residents in becoming economically
This spending item is part of a $24,922,586 allocation. See details
Administration for Children and Families 4/10/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $661,320 Trans-NIH Recovery Act Research Support N-linked glycoproteins and the pathways that produce them are integral in human health and disease since these glycoconjugates play fundamental roles in virtually all aspects of cellular function. Therefore, a detailed, molecular understanding of the pro National Institutes of Health 9/08/2009
BROAD INSTITUTE, INC., THE $657,600 Trans-NIH Recovery Act Research Support Epigenetic modifications have been recognized as important factors in modification of gene expression levels, specification of cellular state and developmental potential, and etiology of cancer. In particular, post- translational modifications to histone National Institutes of Health 7/16/2009
BROAD INSTITUTE, INC., THE $657,600 Trans-NIH Recovery Act Research Support Epigenetic modifications have been recognized as important factors in modification of gene expression levels, specification of cellular state and developmental potential, and etiology of cancer. In particular, post- translational modifications to histone National Institutes of Health 7/16/2009
RADIATION MONITORING DEVICES, INC. $656,503 Trans-NIH Recovery Act Research Support SBIR award, year 2 funding for project entitled High Performance Transparent Optical Ceramic Scintillators through Technology. Public Health Relevance: The proposed research will investigate a promising detector technology which should have a major impac National Institutes of Health 8/05/2010
BROAD INSTITUTE, INC., THE $654,718 Trans-NIH Recovery Act Research Support Because of the diversity of niches they inhabit, their versatility, and the threat their members pose to human health, Gram-positive bacteria are of paramount importance to multiple facets of microbiology. Nonetheless, there has been no systematic effort
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 9/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $648,601 Trans-NIH Recovery Act Research Support Kidney disease is one of the leading health-care costs. Despite the vital importance of the kidney to maintaining the normal physiological equilibrium of an individual, there is a relatively poor understanding of the developmental program that creates the National Institutes of Health 9/30/2009
TRUSTEES OF TUFTS COLLEGE INC $638,930 National Center for Research Resources, Recovery Act Construction Support In this proposal we request funding to create an intellectually- and technologically-advanced research environment focused on understanding the patterns and mechanisms of normal development and disease progression using a multi... Show more National Institutes of Health 3/31/2010
NEW ENGLAND RESEARCH INSTITUTES, INC. $627,705 Trans-NIH Recovery Act Research Support The Urinary Incontinence Treatment Network (UITN) is a clinical research network, including nine clinical centers (CCs) and a data coordinating center (DCC), established by the NIH in 2000 to bring quality investigation to incontinence research. The prima National Institutes of Health 9/28/2009
FICUS CONSULTING GROUP LLC, THE $621,000 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
BROAD INSTITUTE, INC., THE $617,960 Trans-NIH Recovery Act Research Support We propose to perform DNA resequencing collected cohorts with extreme lipid phenoptypes (elevated LDL-C, triglycerides and HDL-C). We will resequence areas of the genome that have been identified as potential loci affecting lipid traits in genome wide ass
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/21/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $612,145 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The exquisite alignment of projections from the two eyes in central visual structures is fundamental for a precise representation of the visual world. We have discovered that the transmembrane protein Ten_m3 is a criti National Institutes of Health 1/29/2010
BROAD INSTITUTE, INC., THE $611,323 Trans-NIH Recovery Act Research Support The goal of The Cancer Genome Atlas (TCGA) is to completely characterize the genomes of all human cancer types. During the past three years, the pilot project of TCGA has committed to studying 500 tumor/normal pairs of glioblastoma, serous adenocarcinoma National Institutes of Health 9/04/2009
BROAD INSTITUTE, INC., THE $608,811 Trans-NIH Recovery Act Research Support Specific Aims: 1) Implement a robust and exportable informatics pipeline that will produce allele-specific copy number information and purity and ploidy estimates using SNP array data. 2) Assess the potential of the low-cost HumanCytoSNP-12 array platfor National Institutes of Health 9/17/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $607,548 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-MH-102: Technologies to study neuronal signaling, plasticity, and neurodevelopment. The complex and diverse fu National Institutes of Health 9/03/2010
FOOD PROJECT, INC., THE $600,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work The Commission's nutrition/physical initiative will support 1) decrease consumption of sugar-sweetened beverages; 2) increased active transit through a new bike share program and implementation of Complete Street policies; 3) impr... Show more
This spending item is part of a $6,411,167 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $595,221 Trans-NIH Recovery Act Research Support Medicinal plants produce a wealth of pharmaceutical compounds such as taxol, vincristine, and morphine. Unfortunately, the specialized secondary metabolic pathways leading to such compounds remain poorly understood and progress in elucidating and manipula
This spending item is part of a $6,000,000 allocation. See details
National Institutes of Health 9/30/2009
COMMUNITY ACTION AGENCY OF SOMERVILLE INC $587,227 ARRA - Community Services Block Grant The Community Services Block Grant program improves the economic and social well-being of low-income individuals and families of the Commonwealth. The overall objective of the CSBG-ARRA program is to assist low-income residents in becoming economically
This spending item is part of a $24,922,586 allocation. See details
Administration for Children and Families 4/10/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $580,581 Trans-NIH Recovery Act Research Support Endothelial response to fluid shear stress has been strongly implicated as a key factor in the focal development of atherosclerotic lesions in human arteries. The hypothesis of this grant is that the glycocalyx plays a pivotal role in the transduction of
This spending item is part of a $933,519 allocation. See details
National Institutes of Health 6/01/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $573,255 Trans-NIH Recovery Act Research Support Vision provides us with information about the objects in the world around us; it also allows us to see the materials that they are made of. Material perception is important: for example, it lets people see whether a sidewalk is icy and it permits a physic National Institutes of Health 9/30/2009
SOMERVILLE MENTAL HEALTH ASSOCIATION INC $573,050 ARRA - Head Start This award provides for ARRA Early Head Start Program expansion to increase the number of families we serve by an additional 22 families. In addition, this grant awards funds for training and technical assistance to improve staff qualifications. Our pro Administration for Children and Families 11/18/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $571,200 Trans-NIH Recovery Act Research Support Several years ago, our laboratory initiated a research program to explore small molecule-nucleic acid conjugates as substrates for an unusual form of organic synthesis in which a small molecule?s reactivity is determined by its attached DNA or RNA sequenc National Institutes of Health 9/28/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $556,963 Trans-NIH Recovery Act Research Support BRCA1 mutations trigger high penetrance breast carcinogenesis. Most such tumors are triple negative/basal-like. How loss of BRCA1 function elicits breast cancer development and why it does so at markedly high rates and, often, at abnormally young ages is National Institutes of Health 9/09/2009
INSTITUTE FOR HEALTHCARE IMPROVEMENT $545,720 The purpose of this award is to strengthen the link between evidence production and strategies for conveying information in ways that encourage the uptake of CER among providers and patients. IDEO shall conceptualize, design, pilot, evaluate and recommen
This spending item is part of a $2,973,753 allocation. See details
Program Support Center 7/12/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $536,274 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-AR-101: Autoimmunity For Diseases Of The Skin, Joints, Muscle And Other Tissues-Develop reagents and analytic methods to identify, characterize, track,
This spending item is part of a $999,659 allocation. See details
National Institutes of Health 9/21/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $532,212 Trans-NIH Recovery Act Research Support The ultimate goal of this research is to fundamentally change the ways in which behavioral interventions are delivered. We propose an innovative mobile Enabling Technology-iHeal-that recognizes stressors that threaten a patients recovery and then delivers
This spending item is part of a $995,654 allocation. See details
National Institutes of Health 9/28/2009
CAMBRIDGE PUBLIC HEALTH COMMISSION $517,106 Trans-NIH Recovery Act Research Support The proposed research is designed to improve the effectiveness of identification, referral and screening for mental health disorders potentially associated with ethnic/racial disparities in adolescent receipt of mental health care. Using data from the Nat
This spending item is part of a $999,892 allocation. See details
National Institutes of Health 9/22/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $516,000 Trans-NIH Recovery Act Research Support Capitalizing on our group's experience on single molecule enzymology, we propose a novel method for multiplex sequencing of individual nucleic acid molecules using a sequencing-by-synthesis approach that employs fluorogenic nucleotide substrates. Upon inc National Institutes of Health 9/16/2010
ALNYLAM PHARMACEUTICALS, INC. $503,576 Trans-NIH Recovery Act Research Support Coronary heart disease is the leading cause of mortality in both men and women worldwide and incidence is highly correlated with levels of cholesterol and triglycerides (fat) in the blood. Plasma concentrations of LDL and HDL cholesterol, as well as trig
This spending item is part of a $4,700,000 allocation. See details
National Institutes of Health 9/28/2009
SOUTH MIDDLESEX OPPORTUNITY COUNCIL, INC. $500,870 ARRA - Community Services Block Grant The Community Services Block Grant program improves the economic and social well-being of low-income individuals and families of the Commonwealth. The overall objective of the CSBG-ARRA program is to assist low-income residents in becoming economically
This spending item is part of a $24,922,586 allocation. See details
Administration for Children and Families 4/10/2009
TRUSTEES OF BOSTON UNIVERSITY $500,000 Recovery Act Comparative Effectiveness Research - AHRQ This application addresses broad needs for comparative effectiveness research and proposes to conduct and analytic epidemiologic studies of retrospective cohort design, to assess the benefits and harms of preventive or therapeutic interventions i... Show more Agency for Healthcare Research and Quality 9/28/2010
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $499,968 Trans-NIH Recovery Act Research Support Funds were requested to purchase a complete Genome Analyzer-IIx sequencer package including cluster station and paired-end read module from Illumina technologies. The system will provide critically needed capacity for an overburdened sequencing pipeline t National Institutes of Health 4/08/2010
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $499,839 Trans-NIH Recovery Act Research Support These funds will be used to purchase a Zeiss LSM710 scanning confocal microscope, to be made available to both Whitehead and MIT investigators. Scanning confocal microscopes allow optical sectioning of living and fixed material, so that investigators can National Institutes of Health 5/13/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $499,106 Trans-NIH Recovery Act Research Support We propose to conduct high-throughput sequencing of cDNAs using a strand-specific, paired-end version of the Illumina mRNA-Seq protocol from a total of 10 specific tissues (cerebral corex, heart, liver, skeletal muscle, testis, spleen, cerebellum, colon, National Institutes of Health 8/12/2010
MCLEAN HOSPITAL CORPORATION, THE $499,016 Trans-NIH Recovery Act Research Support This proposal is to fund a complete refurbishment of the McLean Hospital 4 Tesla Varian Whole Body Multinuclear Magnetic Resonance Imaging system. This instrument has been extremely productive since it was first installed in May, 2001 both as a developmen National Institutes of Health 3/18/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $498,721 Trans-NIH Recovery Act Research Support A large body of both human and animal data support the idea that adolescent behaviors can have life-long effects on an individual. This sensitivity may derive, in part, from the dramatic developmental changes in brain function that are taking place at thi
This spending item is part of a $998,950 allocation. See details
National Institutes of Health 9/25/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $489,401 Trans-NIH Recovery Act Research Support In this proposal six faculty of the Departments of Biology and of Chemistry at MIT request funding for automated macromolecular crystallization equipment to be installed at MIT's Structural Biology Core Facility. MIT structural biologists have lacked un National Institutes of Health 4/28/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $488,908 National Center for Research Resources, Recovery Act Construction Support DESCRIPTION (provided by applicant): The Animal Resource Program at MIT represents a vital resource that is central to the various biomedical research missions of the Institute. This award provides funds to renovate and equip t... Show more
This spending item is part of a $15,000,000 allocation. See details
National Institutes of Health 1/13/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $481,115 Trans-NIH Recovery Act Research Support iPS Cells As Models of ALS: To gain an understanding of the mechanisms underlying any given disease requires access to relevant cell classes on the same genetic background. Although ALS research has seen significant advances over recent years, this precon
This spending item is part of a $3,782,000 allocation. See details
National Institutes of Health 9/28/2009
MASSACHUSETTS EHEALTH COLLABORATIVE, INC $480,500 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
BOSTON COLLEGE, TRUSTEES OF $469,500 Trans-NIH Recovery Act Research Support Control of Early Embryonic Cell Polarity in a Model Deuterostome: Our results thus far include: he cytoskeleton is involved in the establishment and maintenance of the non-uniform distribution of membrane domains in the plasma membrane. It has been prev National Institutes of Health 6/25/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $459,738 Trans-NIH Recovery Act Research Support Previous results have indicated that the motor cortices may execute voluntary movement by selecting and combining muscle synergies organized in the brainstem and/or spinal cord. The specific aims of this research were formulated to test the above hy
This spending item is part of a $628,172 allocation. See details
National Institutes of Health 9/24/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $453,600 Trans-NIH Recovery Act Research Support Epigenetic mechanisms make gene expression patterns stable by maintaining gene regulatory information through cell divisions. Proteins encoded by the Drosophila Polycomb Group (PcG) genes maintain key patterns of gene expression during development, likely National Institutes of Health 9/25/2009
BOSTON COLLEGE, TRUSTEES OF $439,613 Trans-NIH Recovery Act Research Support The award is to purchase/upgrade two NMR spectrometers for use in the Chemistry Department at Boston College. To that end we have negotiated with Varian Instruments for a upgrade to an existing 400 MHz spectrometer (all but the magnet is new) and a new 50 National Institutes of Health 5/01/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $438,940 Trans-NIH Recovery Act Research Support The genetic variability and Individual variations in immune status dictate responses to vaccinations, infections, and contribute to disease severity. The sequencing of the human genome and generation of the Haplotype Map now enables a mechanistic understa
This spending item is part of a $4,456,091 allocation. See details
National Institutes of Health 7/12/2010
FORSYTH DENTAL INFIRMARY FOR CHILDREN $435,500 Trans-NIH Recovery Act Research Support This application requests funds for the purchase of a BD FACSAria II flow cytometer / cell sorter. This application arises from the breakdown of the current flow cytometer, and from a growing demand for flow cytometric cell sorting services among a user g National Institutes of Health 3/11/2010
MCLEAN HOSPITAL CORPORATION, THE $434,500 Trans-NIH Recovery Act Research Support Parkinson disease (PD) is caused by a progressive loss of the dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Although the etiology of PD is still unknown, there is increasing evidence that it is a complex disorder influenced by a combi National Institutes of Health 9/15/2009
MCLEAN HOSPITAL CORPORATION, THE $434,500 Trans-NIH Recovery Act Research Support GABAergic interneurons, born in remote germinative zones in the ventral forebrain (telencephalon) migrate tangentially into the cortex to adopt their specific positions. The cell types and molecular cues that regulate this migration remain to be elucidate National Institutes of Health 5/15/2009
BOSTON COLLEGE, TRUSTEES OF $430,375 Trans-NIH Recovery Act Research Support Forward genetics has been instrumental to understand gene function in well-studied model organisms such as yeast, fruitfly, the worm, and zebrafish. However, molecular genetic mapping methods used in these model systems are time-consuming and laborious. M National Institutes of Health 6/01/2009
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $425,500 Trans-NIH Recovery Act Research Support The research supported by this equipment award will increase understanding of several organ and tissue systems and functions that play significant roles in the development in human disease and aging. These include cell movement in the body tissues, muscl National Institutes of Health 3/04/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $423,119 Trans-NIH Recovery Act Research Support This application addresses Broad Challenge Area (15) Translation Science and Specific Challenge Topic: 15-NS-103 Demonstration of 'proof-of-concept' for a new therapeutic approach in a neurological disease. Alzheimer's disease (AD) is an irreversible neur
This spending item is part of a $823,051 allocation. See details
National Institutes of Health 9/29/2009
Holt Productions LLC $419,308 Trans-NIH Recovery Act Research Support The Hastings Center (the nation's first and foremost bioethics research organization), NOVA (the nation's most-watched science program) and WGBH (PBS's leading producer of programming) have partnered to research whether a multi-platform media project can
This spending item is part of a $960,349 allocation. See details
National Institutes of Health 9/26/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $419,265 Trans-NIH Recovery Act Research Support Tau is a natively unfolded protein that has been implicated in the pathogenesis of several neurodegenerative disorders such as Alzheimer's disease (AD). A number of studies suggest that aggregates of tau contribute to neuronal death and dysfunction in AD National Institutes of Health 5/15/2009
REGIS COLLEGE $416,580 ARRA - Nurse Faculty Loan Program The goal and purpose of the ARRA - Nurse Faculty Loan Program (NFLP) is to increase the number of qualified nurse faculty. Regis College accomplishes this by providing loans to aspiring nurse faculty who are enrolled in the Doctor of Nursing Practice Prog Health Resources and Services Administration 6/14/2010
ABT ASSOCIATES INC. $415,322 The U.S. Office of the National Coordinator for Health Information Technology has awarded a number of contracts, through the Agency for Health Research and Quality, together comprising the Health Information Technology Research Center (HITRC). HITRC devel
This spending item is part of a $1,155,895 allocation. See details
Agency for Healthcare Research and Quality 3/31/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $414,786 Trans-NIH Recovery Act Research Support This project is in the area of reproductive immunology, i.e. the immunological interaction between maternal and fetal tissues. Its goal is to understand maternal-fetal tolerance, i.e. the lack of maternal rejection of the fetus that carries foreign patern National Institutes of Health 7/22/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $411,215 Trans-NIH Recovery Act Research Support This award will enable the development of new methods for the synthesis of enantiomerically enriched organic molecules that are anticipated to have unique activity toward biological targets of importance in cancer therapy. National Institutes of Health 9/16/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $410,298 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (12) Science, Technology, Engineering and Mathematics Education (STEM) and specific Challenge Topic 12-OD-104: Innovative Approaches to STEM Education. One of the cent National Institutes of Health 9/24/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $407,820 Trans-NIH Recovery Act Research Support This ARRA supplement will support screening for inhibitors of a particular gene product i order the find lead compounds new class of antibiotic. The gene, found in the genome of every bacterium in the world, is know a ybeY in E. coli and is a member of th National Institutes of Health 7/16/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $402,268 Trans-NIH Recovery Act Research Support Our aim is to exploit newly developed device and material technologies to build drug delivery devices for urological indications. We will demonstrate devices to replace intravesical therapies that require frequent instillations of drug solutions into the National Institutes of Health 9/07/2009
BROAD INSTITUTE, INC., THE $399,902 Trans-NIH Recovery Act Research Support New, sensitive and specific diagnostic and prognostic tests for early detection of cancer are desparately needed. This award aims to significantly expand the number of novel cancer-related assays that our project will develop. A second component of this p National Institutes of Health 9/29/2009
AMBERGEN, INC $399,000 Trans-NIH Recovery Act Research Support This overall parent project aims to develop a new, highly sensitive, mutation scanning technology for the molecular analysis of cancer. While broadly applicable in oncology, the initial commercial product which is the focus of the parent Phase II SBIR pro National Institutes of Health 9/25/2009
BROAD INSTITUTE, INC., THE $396,497 Trans-NIH Recovery Act Research Support The mitochondrion is the center stage for energy metabolism, apoptosis, signaling, and ion homeostasis. Much of what we know about this organelle comes from studying mitochondrial respiratory chain disease (RCD). This devastating disease is due to genetic
This spending item is part of a $1,970,678 allocation. See details
National Institutes of Health 9/30/2009
MCLEAN HOSPITAL CORPORATION, THE $391,415 Trans-NIH Recovery Act Research Support Cue-induced craving is currently not well understood in nicotine dependence, and is a poor predictor of use. However, as with other drugs of abuse, studies suggest that craving measures become more relevant to drug use when the opportunity to use more clo National Institutes of Health 7/16/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $391,270 Trans-NIH Recovery Act Research Support This is a translational medical research effort whose long-term goal is to develop a photochemotherapeutic system for prevention, control and/or treatment of periodontitis based on recent advances in photomedicine and nanotechnology. Biofilms that coloniz
This spending item is part of a $531,362 allocation. See details
National Institutes of Health 4/27/2009
NEW ENGLAND RESEARCH INSTITUTES, INC. $384,287 Trans-NIH Recovery Act Research Support This project utilizes dietary data that was collected as part of the Boston Area Community Health (BACH) study to help fill knowledge gaps in the nutritional epidemiology of urogynecologic symptoms in a diverse, random community-based sample. Lower urinar National Institutes of Health 9/18/2009
NEW ENGLAND RESEARCH INSTITUTES, INC. $383,808 Trans-NIH Recovery Act Research Support Prescription drug sales have increased nearly 90% between 2000 and 2006, with further increases likely given the January 1, 2006 implementation of prescription drug benefits for seniors. Urologic symptoms are also on the increase; the projected burden of National Institutes of Health 8/17/2009
TRUSTEES OF TUFTS COLLEGE INC $383,750 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Over the past five years, thanks to support from NICHD, we have been actively studying the time-course and neural correlates of word processing in university students learning a second language. In this work we use the National Institutes of Health 9/07/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $382,223 Trans-NIH Recovery Act Research Support The purpose of this grant application was to screen chemical and small interfering RNAs (siRNA) libraries to identify chemical probes and siRNAs that modify three distinct arms of IERSR. The probes generated through this effort will be critical for elucid National Institutes of Health 5/14/2009
MCLEAN HOSPITAL CORPORATION, THE $380,790 Trans-NIH Recovery Act Research Support This R21 application responds to PA-07-227, which describes an urgent need for a greater understanding of the underlying neurobiological and behavioral mechanisms in the addictive effects of methamphetamine (MA) and cocaine. The use and abuse of MA and co National Institutes of Health 6/19/2009
Culbert Healthcare Solutions I $379,500 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
BOSTON COLLEGE, TRUSTEES OF $378,000 Trans-NIH Recovery Act Research Support A General Bayesian Polymorphism Discovery Tool: This project is aimed at the creation of a computer software package that can be used for the discovery of single-nuclotide polymorphisms (SNPs) and short insertion / deletion type genetic variations (short National Institutes of Health 9/18/2009
SIMULCONSULT, INC. $377,991 An Evidence-Based, Open Database Approach to Diagnostic Decision Support National Institutes of Health 9/20/2010
SIMULCONSULT, INC. $377,991 An Evidence-Based, Open Database Approach to Diagnostic Decision Support National Institutes of Health 9/20/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $370,440 Trans-NIH Recovery Act Research Support This ARRA supplement will help us capitalize on our recent molecular insights gained in the parent grant by developing a high-throughput assay to screen for molecules that specifically inhibit Rev1/Rev3/Rev7-dependent translesion synthesis (TLS), which is National Institutes of Health 8/15/2009
TRUSTEES OF TUFTS COLLEGE INC $363,102 Trans-NIH Recovery Act Research Support Cholera has reemerged as a global killer with the world witnessing an unprecedented rise in cholera infection and transmission. The causative agent of cholera is Vibrio cholera, a natural inhabitant of environment but is more prevalent in coastal ecosyste
This spending item is part of a $499,582 allocation. See details
National Institutes of Health 11/06/2009
OUTCOME SCIENCES, INC. $356,493 The proposed BWH DEciDE Methods Center & Network will complement and support new research and evidence development activities that will be conducted under DEciDE and other funding mechanisms involving ARRA funds. In collaboration with AHRQ we will propose
This spending item is part of a $3,934,148 allocation. See details
Agency for Healthcare Research and Quality 7/13/2010
BRANDEIS UNIVERSITY $355,784 Trans-NIH Recovery Act Research Support This is to continue NINDS funding of a Core Facility at Brandeis University. This will allow us to fully exploit the three subcomponents that are now firmly established: a microarray and FACS facility, an imaging facility and a mouse/transgenic facility. National Institutes of Health 9/24/2009
LIFE IMAGE INC. $347,584 The Contractor shall provide services to the National Institute of Biomedical Imaging and Bioengineering (NIBIB) in the design, development, and launch of an Internet-based network for patient-controlled medical image sharing built upon the Integrating th
This spending item is part of a $4,697,377 allocation. See details
National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $346,929 Trans-NIH Recovery Act Research Support Our goal is to test the expression output of tens of thousands of candidate enhancers in a single experiment. This can be of great use in testing predicted candidate enhancers across the genome arising from our chromatin work in the context of ENCODE and
This spending item is part of a $372,834 allocation. See details
National Institutes of Health 8/06/2010
NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. $345,400 Trans-NIH Recovery Act Research Support This project proposes to evaluate the feasibility of an online parenting training approach for influencing mother-adolescent communication about drugs. Parent-adolescent communication has consistently emerged as an important deterrent to initiation and p National Institutes of Health 5/21/2009
DM-STAT, INC $345,067 Trans-NIH Recovery Act Research Support This award will allow the Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) Network to expand into additional sites and collect fetal heart rate data using the Monica device in the Northern Plains (Sanford Health, Pine Ridge Indian He National Institutes of Health 9/29/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $344,260 Trans-NIH Recovery Act Research Support In this project we seek to pursue as a new and additional specific aim the development of practical synthetic routes to the cortistatin family of alkaloids, broadly defined. Our approach is based on a versatile advanced synthetic template from which a div National Institutes of Health 9/23/2009
UNIVERSITY OF MASSACHUSETTS $340,602 Trans-NIH Recovery Act Research Support The New England Consortium (TNEC), based at the University of Massachusetts at Lowell, received $373,270 to provide worker health and safety training courses related to the handling of hazardous materials and hazardous waste to students identified by work
This spending item is part of a $373,270 allocation. See details
National Institutes of Health 9/06/2009
4S3 BIOSCIENCE INC. $336,682 Trans-NIH Recovery Act Research Support Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. Generation of the protein fusion will be followed by testing its activity in cell lines from human patients, ultimately testing its efficacy in mou National Institutes of Health 7/20/2009
4S3 BIOSCIENCE INC. $336,682 Trans-NIH Recovery Act Research Support Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. Generation of the protein fusion will be followed by testing its activity in cell lines from human patients, ultimately testing its efficacy in mou National Institutes of Health 7/20/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $336,000 Trans-NIH Recovery Act Research Support Through alternative splicing, most human genes produce multiple distinct mRNA and protein isoforms, that may differ in structure, localization and function. To understand how splicing is controlled, we are seeking to identify sequences that can act as sp National Institutes of Health 9/30/2009
COMMUNITY TEAMWORK,INC. $332,181 ARRA - Head Start ARRA Cost of Living Adjustment (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act., serving children in Lowell, MA. Head Start is US program designed to help children from birth to age five, Administration for Children and Families 6/26/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $329,696 ARRA - Strategic Health IT Advanced Research Projects (SHARP) We propose research that will generate a framework of open source services that can be dynamically configured to transform HER data into standards-conforming, comparable information suitable for large-scale analyses, inferencing, and integ... Show more
This spending item is part of a $15,000,000 allocation. See details
Health and Human Services, Department of 3/19/2010
FORSYTH DENTAL INFIRMARY FOR CHILDREN $316,252 Trans-NIH Recovery Act Research Support The focus of this supplement is to determine if cathepsin K is essential for proper dental enamel formation. The parent grant focused on defining how enamelysin (matrix metalloproteinase-20; MMP20) processes enamel proteins and focused on determining how National Institutes of Health 9/21/2009
BRANDEIS UNIVERSITY $315,917 Trans-NIH Recovery Act Research Support Synapses are specialized sites of cell-cell contact that mediate communication between neurons in the nervous system. Much remains to be discovered about the molecular mechanisms that underlie formation of these critical structures in the mammalian centra National Institutes of Health 8/10/2009
CHARLES STARK DRAPER LABORATORY, INC., THE $314,256 Trans-NIH Recovery Act Research Support Our tissue engineering approach to heart muscle regeneration combines heart cells with a biodegradable polymer template (scaffold) in a laboratory culture device (bioreactor) to create a contractile heart muscle graft. Such tissue engineered cardiac graft
This spending item is part of a $1,265,929 allocation. See details
National Institutes of Health 6/01/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $311,563 Trans-NIH Recovery Act Research Support This supplement was awarded so we could create and preserve jobs, build our scientific infrastructure, and accelerate the pace and expand the objectives within the scope of our Reprogramming grant. To this purpose, we have hired a new postdoc, Dr. Haoyi National Institutes of Health 7/19/2010
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $308,211 Trans-NIH Recovery Act Research Support To investigate the role of the molecular motor, Myo1c, in hearing. The broad, long-range goal of this study is to determine the molecular mechanism of hearing and balance.
This spending item is part of a $339,011 allocation. See details
National Institutes of Health 7/17/2009
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $305,621 Funds to purchase Adult Influenza Vaccine Centers for Disease Control and Prevention 6/08/2009
BROAD INSTITUTE, INC., THE $301,227 Trans-NIH Recovery Act Research Support The long-term goal of this project is to understand the genomic mechanisms that generate phenotypic diversity in vertebrates. Rapid progress in genomics has provided nearly complete sequences for several organisms. Comparative analysis suggests many funda
This spending item is part of a $849,841 allocation. See details
National Institutes of Health 9/16/2010
BROAD INSTITUTE, INC., THE $301,181 Trans-NIH Recovery Act Research Support Germinal center (GC) B-cell lymphomas are clinically and genetically heterogeneous disorders. The incidence of the most common GC B-cell lymphomas has increased dramatically in recent years, with a 50% rise in the last generation. The participants of this
This spending item is part of a $1,061,795 allocation. See details
National Institutes of Health 9/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $300,592 Trans-NIH Recovery Act Research Support Fast and reliable intra-operative diagnosis is a critical component of successful oncological surgery in a variety of organ systems. While optical probe and in vivo imaging strategies have been proposed by us and others as potential tools for surgical mar National Institutes of Health 8/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $300,544 Trans-NIH Recovery Act Research Support Title: Engineering Skeletal Muscle with Biodegradable Hydrogels. Skeletal muscle tissue is often required in reconstructive craniofacial surgery, and the long-term goal of the applicants? research is to regenerate functional craniofacial skeletal muscle. National Institutes of Health 9/21/2009
UNIVERSITY OF MASSACHUSETTS $298,990 ARRA ? Equipment to Enhance Training for Health Professionals The purpose of the Equipment to Enhance Training for Health Professionals (EETHP) is to support training for pre-entry preparation and retention of high-quality educationally and economically disadvantaged (including racial/ethnic minoriti... Show more Health Resources and Services Administration 9/03/2010
VERISTAT, INC $298,800 Perform studies under Antigen Sparing contract relating to H1N1 and other strains of pandemic influenza vaccine.
This spending item is part of a $62,478,417 allocation. See details
Health and Human Services, Department of 9/28/2009
APPLIED MANAGEMENT SYSTEMS, INC. $291,500 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $289,931 Trans-NIH Recovery Act Research Support Protein-protein interactions (PPIs) play a central role in all biological processes. Akin to the complete sequencing of genomes, complete descriptions of interactomes is a fundamental step towards a deeper understanding of biological processes, and has a National Institutes of Health 8/14/2009
AKAZA RESEARCH, LLC $289,771 Trans-NIH Recovery Act Research Support We believe a key barrier to transforming clinical research is the lack of open, integrated, transparent technology solutions that address bottlenecks in information integration and business process management. Our viewpoint is supported by a recent Forres National Institutes of Health 6/10/2010
JEN ASSOCIATES INC $288,792 The objective of this contract is to build and operate a multi-payer claims database (MPCD) to support CER using Medicare, Medicaid, other public payer, and private payer claims data and to enable access to the database for researchers, policymakers, and
This spending item is part of a $16,436,482 allocation. See details
Health Care Financing Admin. (was Medicare and Medicaid Serv.) 9/14/2010
NOVARTIS VACCINES AND DIAGNOSTICS, INC. $286,035 Funds to Purchase Pediatric Influenza Vaccine Centers for Disease Control and Prevention 5/13/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $279,566 Trans-NIH Recovery Act Research Support This Administrative Supplement to our NIMH grant (2R01MH065252-08 - The Neural Basis of Categories) is for the topic of Enhancing Research Grants and Capacities through Infrastructure Support. Our NIMH-funded project examines a foundation of cognition: t National Institutes of Health 7/17/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $279,295 Trans-NIH Recovery Act Research Support The Forsyth Institute proposes to obtain a Zeiss Evo LS 10 scanning electron microscope (SEM) equipped with an Oxford INCA Energy 250 energy dispersive x-ray elemental analysis system (EDS. The purpose is to replace 20 year old SEM with deteriorating func National Institutes of Health 6/10/2010
BRANDEIS UNIVERSITY $278,466 Trans-NIH Recovery Act Research Support This proposal is a Recovery Act Competitive Revision as specified in notice number NOT-OD- 09-058, NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent grant is R01 GM054403, IMP Dehydrogenase. IMP dehydro National Institutes of Health 9/29/2009
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $277,130 Trans-NIH Recovery Act Research Support The parent grant supports research to synthesize and analyze the major experimental early childhood intervention programs and non-experimental studies of family influence. Three tasks were delineated in the original proposal: (1) to put the intervention National Institutes of Health 9/29/2009
REGIS COLLEGE $276,755 ARRA - Nurse Faculty Loan Program ARRA - Nurse Faculty Loan Program (NFLP) for Aspiring Nurse Faculty Enrolled in the Master's Program Health Resources and Services Administration 8/10/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $276,190 Trans-NIH Recovery Act Research Support The goal of this work is a structure-based understanding of how DNA replication is initiated. Replication initiates at multiple sites on the genome called origins of DNA replication. Specialized protein complexes bind at these sites and prepare the duplex National Institutes of Health 9/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $276,166 Trans-NIH Recovery Act Research Support The funds requested were for (a) additional supplies to expand high throughput sequencing of RNA populations, (b) to purchase an essential instrument for quantization of images and (c) to support the extension of a postdoctoral appointment for a year to i National Institutes of Health 9/04/2009
LOWELL COMMUNITY HEALTH CENTER INC $275,972 ARRA Health Center Integrated Services Development Initiative[g1] Increased support for Health Centers - The purpose of this award is to support expanded access to clinical services to the residents of Lowell, Massachusetts. This will be achieved through expanded hours of operation in our clinic and... Show more Health Resources and Services Administration 3/27/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $275,333 Trans-NIH Recovery Act Research Support The primary aim of our parent grant focuses upon predicting the benefit of altering the properties or expression level of individual enzymes. The crux of this proposed supplementary project is to better understand the full spectrum of selective pressures National Institutes of Health 8/13/2009
BROAD INSTITUTE, INC., THE $274,035 Trans-NIH Recovery Act Research Support The genetic variability and Individual variations in immune status dictate responses to vaccinations, infections, and contribute to disease severity. The sequencing of the human genome and generation of the Haplotype Map now enables a mechanistic understa
This spending item is part of a $4,456,091 allocation. See details
National Institutes of Health 7/12/2010
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $272,000 Trans-NIH Recovery Act Research Support The goals of the supplement are (1) to accelerate the development of a data access system at the NBER that allows simultaneous use of various country surveys on health and aging that are being conducted around the world, and (2) to enhance the consol National Institutes of Health 9/24/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $271,872 Trans-NIH Recovery Act Research Support Our supplement Aim is to determine the role of neural synchrony in learning and implementing rules by recording neural activity with a denser electrode array. One of the vexing questions of systems neuroscience is how multiple types of information (e.g., National Institutes of Health 9/25/2009
PROVIA LABORATORIES, LLC $265,100 The Cancer Human Biobank (caHUB) - This is a national, standardized , biospecimen resource for the collection of human tissues which are a critical resource for cancer research. Contracts will be established with medical research adn healthcare entities
This spending item is part of a $60,000,000 allocation. See details
National Institutes of Health 9/04/2009
COMMUNITY TEAMWORK,INC. $264,908 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
Vitality Inc $261,120 Trans-NIH Recovery Act Research Support This project proposes to test a novel strategy financial incentives to improve uptake of comparative effectiveness findings among physicians and patients to reduce cardiovascular risk. This project will focus on improving cholesterol control among
This spending item is part of a $12,488,763 allocation. See details
National Institutes of Health 9/16/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $254,544 Trans-NIH Recovery Act Research Support The overall scope of the parent project (5R01 EB 001659) is to develop and evaluate advanced patient-monitoring and clinical decision-support concepts that will improve the efficiency, accuracy, and timeliness of decision-making in critical care. In pursu National Institutes of Health 8/31/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $254,235 Trans-NIH Recovery Act Research Support The major goal of this proposal is to validate measurements of glycated CD59 (the glucose inactivated form of the key complement regulatory protein known as CD59) in human urine, as 1) a biomarker and predictor of vascular diabetic complications, 2) a pat National Institutes of Health 5/31/2010
BROAD INSTITUTE, INC., THE $253,795 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): In this proposal six NIH-funded faculty from the Broad Institute of MIT and Harvard request to purchase a Nanostring nCounterTM Analysis System. Nanostring is a new technology for multiplex measurement of up to 550 gen National Institutes of Health 11/18/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $252,000 Trans-NIH Recovery Act Research Support Herpesviruses are major pathogens in human populations, causing disease in normal and immuno-compromised individuals. Double-stranded DNA (dsDNA) tailed bacterial viruses and herpesviruses share surprising similarities in capsid assembly and organization.
This spending item is part of a $1,011,610 allocation. See details
National Institutes of Health 5/21/2009
NEW ENGLAND RESEARCH INSTITUTES, INC. $250,001 Trans-NIH Recovery Act Research Support The Boston Area Community Health (BACH) Survey is currently supported by U01DK056842 from NIDDK. BACH is a population-based, epidemiologic cohort survey conducted among 5,501 men and women aged 30 to 79 residing in Boston, Massachusetts. A multistage, str National Institutes of Health 9/30/2009
BEDFORD VA RESEARCH CORPORATION, INC., THE $250,000 Trans-NIH Recovery Act Research Support .Abstract G?Metabolomics Network for Drug Response PhenotypeG? Response to Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure G?Grand OpportunitiesG? (RC2), RFAOD- 09-004-Linking Metabolomics to Pharmacogenomics Cardiova
This spending item is part of a $4,507,931 allocation. See details
National Institutes of Health 9/30/2009
BRANDEIS UNIVERSITY $243,968 Trans-NIH Recovery Act Research Support Local regulation of the levels and activity of synaptic proteins is critical to plasticity. In this proposal, we investigate the role of translation in regulation of the levels of CaMKII and characterize the functional roles of the interaction of Eag and National Institutes of Health 7/15/2009
MOLECULAR INSIGHT PHARMACEUTICALS, INC. $243,101 Trans-NIH Recovery Act Research Support Determination of serum prostate specific antigen (PSA) is an effective early screen for potential Prostate cancer with revenues estimated at over $350 million annually. Although the current screening method of PSA levels in the blood is valuable for early National Institutes of Health 9/01/2010
BRANDEIS UNIVERSITY $241,642 Trans-NIH Recovery Act Research Support How cell cycle events are controlled with growth remains an important and perhaps the most important, outstanding question in prokaryotic biology. A group of conserved and essential GTPase proteins, related to Ras, have been implicated in cell cycle contr National Institutes of Health 8/31/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $241,277 Trans-NIH Recovery Act Research Support This supplement builds directly on, and significantly extends the translational impact of Specific Aim 1 in the parent R01 grant: investigating the functional importance of the PX domain of p47phox and PI 3-kinase signaling in NADPH oxidase priming and ac National Institutes of Health 9/30/2009
President & Fellow of Harvard College $239,795 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Research and specific Challenge Topic, 151-AI-106: Translational research focused on high priority pathogens (influenza) and basic research focused on resistance mechanisms. Pandemic influ
This spending item is part of a $995,688 allocation. See details
National Institutes of Health 11/25/2009
MCLEAN HOSPITAL CORPORATION, THE $237,000 Trans-NIH Recovery Act Research Support Methamphetamine (METH) abuse and dependence represent major mental health and law enforcement problems in the US and abroad. PET studies consistently showed chronic reduction in dopamine transporter (DAT) density in the striatum of methamphetamine addicts National Institutes of Health 7/16/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $235,000 Trans-NIH Recovery Act Research Support These funds will be used to purchase an nCounter G?? system from NanoString Technologies. The nCounter system is a new approach to gene expression analysis that offers the data quality of Real-Time PCR with higher multiplexing, better throughput and lower National Institutes of Health 3/04/2010
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $230,250 Trans-NIH Recovery Act Research Support In this application we proposed to study the role of five miRNAs - miR-144, 451, 221, 222, and 223 - in terminal proliferation and differentiation of murine erythroid CFU-E progenitors and in the proliferation of BFU-E progenitors and the formation of CFU National Institutes of Health 9/28/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $229,061 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic 08-CA-104: Regulatory functions of small RNAs. Our goal is to identify small RNAs (smRNAs) as regulators of histone modifying enzymes, mediating interactions with
This spending item is part of a $996,415 allocation. See details
National Institutes of Health 3/24/2010
INSTITUTE FOR HEALTH METRICS CORPORATION $226,960 Trans-NIH Recovery Act Research Support This proposal seeks to investigate the degree of institutional variation in the surgical treatment of breast cancer in community hospitals. The majority of surgery for breast cancer is performed in community hospitals yet the majority of research is perfo
This spending item is part of a $754,311 allocation. See details
National Institutes of Health 9/25/2009
ENVIRONMENT AND HEALTH GROUP, INC. $224,700 Trans-NIH Recovery Act Research Support The parent grant (2 R44 AG026815), E-Technology for Chinese Dementia Caregivers, supports a Phase II SBIR randomized trial that tests a web-based education and social support intervention for Chinese-speaking dementia caregivers. The proposed OppNet resea National Institutes of Health 9/22/2010
BROAD INSTITUTE, INC., THE $222,000 Trans-NIH Recovery Act Research Support Diabetes Prevention Program Outcomes Study (DPPOS) Diabetes Prevention Program (DPP) demonstrated that lifestyle and metformin reduce the risk of diabetes (DM) by 58% and 31% (NEJM 346;393-403,2002). The DPPOS, now in year 7, aims to determine whether re
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 9/28/2009
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $217,478 Trans-NIH Recovery Act Research Support The Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) of 1996, often referred to as welfare reform, ended entitlement to welfare benefits under Aid to Families with Dependent Children (AFDC) and replaced AFDC with Temporary Assistan
This spending item is part of a $793,695 allocation. See details
National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $215,522 Trans-NIH Recovery Act Research Support The primary purpose of this supplemental award is to allow us to purchase a fluorescence microscope. We plan to use the microscope to visualize gene transfer between individual bacterial cells. It will also support a postdoctoral researcher (for 1.5 yea National Institutes of Health 8/14/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $214,380 Trans-NIH Recovery Act Research Support Language development in typical children follows specific developmental sequences and demonstrates inherent biases at certain stages. It is not known to what degree language development in children with autism follows the same development rules or achiev
This spending item is part of a $299,918 allocation. See details
National Institutes of Health 8/01/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $213,912 Trans-NIH Recovery Act Research Support Aneuploidy is the leading cause of miscarriages in humans and a hallmark of cancer. Determining the origins and effects of aneuploidy is thus vital for understanding the principles underlying tumor formation and infertility. We had previously examined the National Institutes of Health 8/31/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $212,721 Enhancing ITK for Research, Education, and Clinical Interoperability.
This spending item is part of a $862,699 allocation. See details
National Institutes of Health 6/21/2010
COMMUNITIES UNITED INC $206,678 ARRA - Head Start Communities United, Inc. (CUI) is a Head Start and Early Head Start grantee. Award 01SE1002/01 was granted to CUI pursuant to Program Instruction ACF-PI-HS-09-06, and provides funding for Cost-of-Living Adjustments and Quality Improvement. Grant monies wi Administration for Children and Families 8/05/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $205,759 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): In this proposal, seven faculty of the Department of Biology and of the Koch Institute for Integrative Cancer Research at MIT request funding to upgrade the liquid-handling robot at MIT's BioMicro Center, a core facili National Institutes of Health 3/18/2010
BROAD INSTITUTE, INC., THE $205,298 Trans-NIH Recovery Act Research Support This ENCODE consortium project aims to identify and classify chromatin regulatory elements in the human genome in systematic fashion. This goal is being pursued through the application of chromatin methods and ultra high-throughput sequencing to acquire g
This spending item is part of a $494,631 allocation. See details
National Institutes of Health 9/22/2009
COMMUNITY ACTION AGENCY OF SOMERVILLE INC $203,419 ARRA - Head Start ARRA Cost of Living Adjustments (COLA), and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. Administration for Children and Families 7/02/2009
SPECTRASILK, INC. $200,000 Trans-NIH Recovery Act Research Support In this grant, we seek to accelerate transitions to clinical trials with a new small diameter silk graft for blood vessels. We will focus on control of blood-silk biomaterial interactions by using a multifunctional approach for spatial regulation of mate National Institutes of Health 9/20/2010
COMMUNITY ACTION AGENCY OF SOMERVILLE INC $200,000 Mentor Coaching Grant Administration for Children and Families 9/16/2010
COMMUNITY ACTION AGENCY OF SOMERVILLE $200,000 ARRA - Head Start Mentoring Coach Grant Administration for Children and Families 9/16/2010
SCIENTIFIC SYSTEMS COMPANY INC. $200,000 Trans-NIH Recovery Act Research Support The research objective of the project is to extract and utilize information from keyword-frequency data obtained from Online Social Networks (OSNs) such as Facebook, MySpace and Twitter, in order to provide timely prediction of the emergence and spread of National Institutes of Health 7/28/2010
NORMATEC INDUSTRIES LP $199,956 Trans-NIH Recovery Act Research Support Pneumatic Medicine: A Transformative Treatment for Diabetic Peripheral Neuropathy National Institutes of Health 9/30/2010
NORMATEC INDUSTRIES LP $199,956 Trans-NIH Recovery Act Research Support Pneumatic Medicine: A Transformative Treatment for Diabetic Peripheral Neuropathy Diabetes frequently leads to decreased sensation in the legs caused by diabetic peripheral neuropathy (DPN). DPN is an important risk factor for the development of foot ulc National Institutes of Health 9/30/2010
4S3 BIOSCIENCE INC. $195,590 Trans-NIH Recovery Act Research Support Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. A second grant extension has been granted to further production efforts to generate significant drug material for testing. National Institutes of Health 6/25/2012
BROAD INSTITUTE, INC., THE $194,369 Trans-NIH Recovery Act Research Support In the work to be supported by this award, we will: 1) Extend the best methodology for imputation to African Americans, producing public-domain software to execute these analyses, validating our methods, and providing a public-domain database of all known
This spending item is part of a $973,538 allocation. See details
National Institutes of Health 9/30/2009
NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. $193,920 Trans-NIH Recovery Act Research Support Advancing the Application of Medicare Claims Records for Health Care Research The goal of this supplement is to accelerate the development of researcher-friendly database resources that are constructed from Medicare claims records. The first projec National Institutes of Health 9/24/2009
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $193,682 Trans-NIH Recovery Act Research Support This is a partial award for the consortium with the Hugo W. Moser Research Institute at Kennedy Krieger effective 9/30/09. These supplemental funds are intended to accelerate the pace of biomarker discovery for FSHD therapeutics and will be targeted spec
This spending item is part of a $342,766 allocation. See details
National Institutes of Health 9/22/2009
BROAD INSTITUTE, INC., THE $193,330 Trans-NIH Recovery Act Research Support We propose to accelerate the application and validation of the PEPPeR platform to biomarker discovery using lung tissue interstitial fluid (TIF) for discovering biomarkers in lung adenocarcinoma. A relatively large set of 20 TIF samples (10 control and 10 National Institutes of Health 9/22/2009
SOUTH MIDDLESEX OPPORTUNITY COUNCIL, INC. $188,249 ARRA - Head Start Financial Assistance Award : Cost-of-Living Adjustment (COLA) increase of 1.84% in the amount of $47,660 for Head Start to pay for staff salaries. Quality Improvement funds of $140,589 for Head Start consistent with the provisions of Section 640(a)(5) of Administration for Children and Families 6/17/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $187,189 Trans-NIH Recovery Act Research Support The long-term objective of this research is to characterize the cultivable and currently uncultivated microorganisms present in the human oral cavity (microbiome) and all of their genes (metagenome) in order to develop an integrated view of host-microbiom National Institutes of Health 5/01/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $184,121 Trans-NIH Recovery Act Research Support Amyloids are implicated in many deadly human diseases from systematic amyloidosis to Alzheimer's Disease. These diseases are responsible for large social and financial costs. Gaining a greater understanding of amyloid structures and the forces that govern National Institutes of Health 1/29/2010
STERN MAGNETICS, LLC $183,490 Trans-NIH Recovery Act Research Support Phase I SBIR National Institutes of Health 7/15/2009
EDUCATION DEVELOPMENT CENTER, INC. $182,419 Trans-NIH Recovery Act Research Support This project is developing materials to augment a multi-year parent education intervention that aims to reduce HIV-related risks among African American and other black youth living in high poverty neighborhoods. Consistent with the goals of the parent gr
This spending item is part of a $299,074 allocation. See details
National Institutes of Health 7/21/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $182,212 Trans-NIH Recovery Act Research Support The purpose of this proposal is to delineate the role of NF-(B subunits in the development of inflammatory bowel disease. NF-(B is a transcription factor family consisting of 5 subunits. Activation of NF-(B in response to Toll-like receptor (TLR) signalin
This spending item is part of a $899,156 allocation. See details
National Institutes of Health 7/17/2009
TRIBOLOGICS $180,127 Trans-NIH Recovery Act Research Support Injury is a well established risk factor in the pathogenesis of osteoarthritis (OA) as supported by several large longitudinal population studies. Patients with meniscal and ACL injuries in particular are at risk for early OA. Chondroprotection of the joi
This spending item is part of a $284,758 allocation. See details
National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $176,902 Trans-NIH Recovery Act Research Support The overall goal of the proposed project is to explore the role of the brain histone epigenome in modulating the effect of life experiences on cognitive decline and dementia. In prior work, we found that while cognitive decline in old age often results fr
This spending item is part of a $998,322 allocation. See details
National Institutes of Health 9/29/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $174,056 Trans-NIH Recovery Act Research Support ARRA funds will enable the support of two new graduate students in the Chemistry/Biology interface training program (CBiTP) at MIT. The CBiTP brings together approximately 30 faculty members from the Departments of Chemistry, Biology, and Biological Engin National Institutes of Health 8/10/2009
NEW ENGLAND COMPLEX SYSTEMS INSTITUTE INC $172,000 Trans-NIH Recovery Act Research Support Asthma is a disease of rapidly increasing incidence that affects more than 17 million people in the United States alone. It is of major importance to understand the causes of heterogeneous ventilation and airway obstruction, cardinal features responsible
This spending item is part of a $898,688 allocation. See details
National Institutes of Health 7/16/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $171,140 Trans-NIH Recovery Act Research Support Delivery of cell-killing doses of ionizing radiation to tumors is the objective of antibody-directed radioimmunotherapy (RIT). In practice however collateral damage to healthy bone marrow and kidneys limits the maximum delivered radiation dose. Pretarge National Institutes of Health 8/31/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $170,150 Trans-NIH Recovery Act Research Support Translation initiation is a crucial point of regulation of eukaryotic gene expression. In response to a variety of environmental insults, cells down-regulate the primary (cap-dependent) mechanism of translation while favoring expression of a select group National Institutes of Health 1/08/2010
METASYSTEMS GROUP, INC $169,900 Metafer Scanning System National Institutes of Health 6/26/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $167,986 Trans-NIH Recovery Act Research Support Paramyxoviruses cause important human illnesses that contribute significantly to global disease and mortality. Two zoonotic paramyxoviruses, Hendra (HeV) and Nipah (NiV), are of urgent concern due to their lethal and transmissible nature. HeV and NiV in
This spending item is part of a $1,527,772 allocation. See details
National Institutes of Health 9/27/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $167,061 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and specific Challenge Topic, 03-DE-101: Development, Refinement, or Validation of Biomarkers Relevant to Oral or Craniofacial Disorders. The goal of this proposed st
This spending item is part of a $954,397 allocation. See details
National Institutes of Health 9/22/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $162,803 Trans-NIH Recovery Act Research Support R01 funding has helped define the forces that drive transport and effect of endogenous signals and exogenously delivered compounds. The timing of this work could not be more critical. Drug-eluting stents (DES) present an innovative technology with great p National Institutes of Health 9/24/2009
MCLEAN HOSPITAL CORPORATION, THE $158,000 Trans-NIH Recovery Act Research Support Human genetic studies have linked genes encoding GABAA receptor ? subunits to mental illnesses like major depression, bipolar disorder, schizophrenia, alcohol dependence, and illicit drug dependence. However, the functions of the products of these genes w National Institutes of Health 7/16/2009
MCLEAN HOSPITAL CORPORATION, THE $158,000 Trans-NIH Recovery Act Research Support Human genetic studies have linked polymorphisms in the gene encoding the GABAA receptor ?2 subunit, GABRA2, to substance abuse, but neuronal mechanism and brain regions involved are still unknown. Recent experimental evidence suggests that a global deleti National Institutes of Health 7/16/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $158,000 Trans-NIH Recovery Act Research Support Relative neuronal vulnerability is a universal yet poorly understood feature of neurodegenerative diseases. In Parkinson's disease (PD), dopaminergic (DA) neurons in the substantia nigra (SN; A9) are particularly vulnerable, whereas adjacent DA neurons wi National Institutes of Health 6/01/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $158,000 Trans-NIH Recovery Act Research Support Relative neuronal vulnerability is a universal yet poorly understood feature of neurodegenerative diseases. In Parkinson's disease (PD), dopaminergic (DA) neurons in the substantia nigra (SN; A9) are particularly vulnerable, whereas adjacent DA neurons wi National Institutes of Health 6/01/2009
CONNECTIVE ORTHOPAEDICS $157,848 Trans-NIH Recovery Act Research Support This study will establish proof of principle for an innovative technique of ACL repair with a device made of collagen and autologous platelets which stimulates healing of the transacted ACL. The advantages over the current gold standard of treatment of A National Institutes of Health 9/29/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $156,624 Trans-NIH Recovery Act Research Support We have recently been able to demonstrate direct homology-dependent pairing of two DNA molecules independent of proteins under physiological conditions. The current administrative supplement is requested so that we can begin to pursue the biological impli National Institutes of Health 12/11/2009
BOSTON COLLEGE, TRUSTEES OF $156,500 Trans-NIH Recovery Act Research Support The purpose of this project is to determine significant attitudes and beliefs that are associated with reporting of dating violence in college women. Achieving this goal will guide research developing and testing effective prevention and intervention str National Institutes of Health 5/05/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $155,053 Trans-NIH Recovery Act Research Support Modulating Cortical and Sub-cortical Brain Circuits in Chronic Facial Pain Chronic pain, especially facial pain is difficult to treat because it is associated with an enormous diversity of nervous system alterations. Characterizations of these changes at
This spending item is part of a $994,174 allocation. See details
National Institutes of Health 9/25/2009
United Way of Tri-County, Inc. $150,000 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
BROAD INSTITUTE, INC., THE $150,000 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic, 08-OD-101, Computational approaches for epigenomic analysis. While the primary DNA sequence of the human genome is ultimately responsible for the encoding and fun
This spending item is part of a $939,401 allocation. See details
National Institutes of Health 9/21/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $148,906 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (14) Stem Cells and specific Challenge Topic, 14-DE-103: Enhancing Human Embryonic Stem (ES) Cell Culture Systems. The overall objective of this proposal is to develop and optimize a feeder-free in vitro cul
This spending item is part of a $975,069 allocation. See details
National Institutes of Health 3/09/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $145,806 Trans-NIH Recovery Act Research Support This research is directed toward improved speech reception for hearing impaired persons and cochlear implantees through a program of research on models of speech intelligibility. The goal is to develop and experimentally evaluate a robust physical metric National Institutes of Health 8/14/2009
BRANDEIS UNIVERSITY $141,922 Trans-NIH Recovery Act Research Support HISTORIES OF SOCIAL ENGAGEMENT & COGNITIVE FUNCTIONING Research has suggested that greater social engagement G?? a term used to refer broadly to both quantitative and qualitative aspects of social interaction G?? is associated with significantly lower r
This spending item is part of a $999,007 allocation. See details
National Institutes of Health 8/14/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $140,650 Trans-NIH Recovery Act Research Support Macular degeneration - the loss of central vision due to retinal damage - is the leading cause of visual impairment in the developed world, affecting more than 1.6 million Americans over the age of 50. Individuals with total loss of central vision must l National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $140,130 Trans-NIH Recovery Act Research Support During prior funding periods, we have produced, crystallized and determined the structure of human (h) CD4 sCD41-183 and HIV-gp41 to high resolution. The structure of hsCD4 in complex with an MHC class II molecule (hsSCD4-pMHCII) was also solved. In conju
This spending item is part of a $617,662 allocation. See details
National Institutes of Health 9/21/2009
TRUSTEES OF TUFTS COLLEGE INC $140,044 Trans-NIH Recovery Act Research Support DNA damage and repair are fundamental to human health and disease. The long-term objectives of this application are to: expand our understanding of the role of DNA helical distortions in DNA damage recognition and processing; determine the factors influen
This spending item is part of a $294,823 allocation. See details
National Institutes of Health 8/10/2009
LIBERATING TECHNOLOGIES INC $139,863 Trans-NIH Recovery Act Research Support The purpose of the R43 award is to determine the feasibility of creating a device that can be incorporated into the prosthesis to improve the circulation in the residual limbs of persons with amputation resulting from vascular complications. The delivera
This spending item is part of a $199,686 allocation. See details
National Institutes of Health 4/15/2010
CAMBRIDGE PUBLIC HEALTH COMMISSION $139,087 ARRA Accelerating Adoption of Comparative Effectiveness Research (CER) The goal of this study is to develop and test system-level interventions to accelerate the adoption of Comparative Effectiveness Research (CER) evidence on childhood obesity screening and management, and ultimately improve obesity... Show more
This spending item is part of a $2,945,066 allocation. See details
Office of Assistant Secretary for Planning and Evaluation 9/20/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $138,530 Trans-NIH Recovery Act Research Support The long-term goal of the parent grant is to understand the molecular basis of early vertebrate embryogenesius with focus on the Nodal signaling pathway. Supplemental ARRA funding is used to employ ChIP-Seq (Chromatin immunoprecipitation) technology and National Institutes of Health 7/17/2009
BROAD INSTITUTE, INC., THE $138,060 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04-HL- 113: Cost-Effective Trials of CVD Prevention in Persons with Low Short-Term Risk. Lipid-lowering therapy with HMG-CoA reductase inhibitors (statins
This spending item is part of a $992,690 allocation. See details
National Institutes of Health 9/21/2009
Concordant, Inc $135,000 ARRA - Health Information Technology Extension Program Regional Extension Center for Commonwealth of Massachusetts In 2008 Massachusetts created the Massachusetts eHealth Institute (MeHI), a division of the Massachusetts Technology Collaborative (MTC), and the Health Information Technology Council (t... Show more
This spending item is part of a $14,507,318 allocation. See details
Health and Human Services, Department of 2/08/2010
ALAN BALL ID, INC. $133,473 Trans-NIH Recovery Act Research Support The volatility of respiratory symptoms due to asthma is related in large measure to the dynamic nature of airway obstruction in this disease. The ability to detect airway obstruction early - respiratory interoception - helps individuals with asthma to man
This spending item is part of a $199,937 allocation. See details
National Institutes of Health 6/01/2010
TRUSTEES OF TUFTS COLLEGE INC $132,160 Trans-NIH Recovery Act Research Support Collagen is the most abundant protein in the body, defined by its unique triple-helical conformation and repeating sequence pattern with glycine as every third residue. Biophysical studies are proposed to relate the (Gly-X-Y)n amino acid sequence and brea
This spending item is part of a $219,440 allocation. See details
National Institutes of Health 9/01/2010
MCLEAN HOSPITAL CORPORATION, THE $131,408 Trans-NIH Recovery Act Research Support This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov National Institutes of Health 9/29/2009
INDUSTRIAL MOTIONS ENGINEERING, INC. $130,000 Trans-NIH Recovery Act Research Support Platelet transfusion is the leading cause of transfusion related bacterial sepsis. Despite the mandated testing of platelet concentrate (PC) for contaminant bacteria, limitations in currently used testing methods continue to result in a significant number
This spending item is part of a $1,998,687 allocation. See details
National Institutes of Health 6/10/2010
MCLEAN HOSPITAL CORPORATION, THE $128,976 Trans-NIH Recovery Act Research Support This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov National Institutes of Health 9/28/2009
ENVIRONMENT AND HEALTH GROUP, INC. $126,581 Trans-NIH Recovery Act Research Support Abstract: HIV infection is on the rise among older women in the U.S. There is an urgent need for culturally-sensitive, gender- specific, and age-appropriate HIV prevention interventions for older women, particularly minority older women who are most at-ri National Institutes of Health 9/21/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $126,475 Trans-NIH Recovery Act Research Support The zebrafish is an ideal model system in which to study the effects of genetic mutations on eye development and function. Its retina contains four types of cones as well as abundant rods, and the animals are highly responsive visually, enabling the analy National Institutes of Health 1/29/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $124,676 Trans-NIH Recovery Act Research Support The broad, long-term objectives of the parent award for this supplement are to understand how proteins establish interaction specificity at the level of individual domains, and to capture this in models that can be used for computational prediction and de National Institutes of Health 9/30/2010
TRUSTEES OF TUFTS COLLEGE INC $124,426 Trans-NIH Recovery Act Research Support Accumulating molecular data increasingly support an active role for adipose tissue (AT) in the development of obesity and related metabolic diseases. While a number of AT-derived signaling factors have been identified, the mechanisms by which these factor
This spending item is part of a $205,298 allocation. See details
National Institutes of Health 4/23/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $123,451 Trans-NIH Recovery Act Research Support We propose to develop an approach for the identification of cis-regulatory sequence elements in mammalian genomes. Our approach calls for simultaneous expression profiling and TF-binding-location analysis under multiple time points and conditions relevant
This spending item is part of a $450,000 allocation. See details
National Institutes of Health 2/10/2010
BRANDEIS UNIVERSITY $122,816 Trans-NIH Recovery Act Research Support A central concern of the present post-genomic era of biology is understanding the chemical and physical mechanisms by which gene expression is regulated. Appropriate activation and repression of particular genes is necessary for maintaining normal cell fu National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $120,518 Trans-NIH Recovery Act Research Support This award is funded under the American Recovery and Reinvestment Act of 2009. This project will allow exploration and invention of new synthetic methodology based on key observations made in the context of the parent grant. This support will allow us t National Institutes of Health 9/24/2009
BRANDEIS UNIVERSITY $119,625 Trans-NIH Recovery Act Research Support During the last several years our research program has made signiificant progress in the development and application of cinchona alkaloids as broadly useful chiral base/nucleophilic catalysts for asymmetric synthesis and in the elucidation of catalyst-sub National Institutes of Health 9/24/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $119,541 Trans-NIH Recovery Act Research Support The broad aim of this Grand Opportunity Grant is to understand how race-based social stress, racial/ethnic (R/E) identity, and biological functioning contribute to health and healthy aging. Using the Maryland Adolescent Development in Context Study (MADIC
This spending item is part of a $900,235 allocation. See details
National Institutes of Health 9/29/2009
BRANDEIS UNIVERSITY $118,595 Trans-NIH Recovery Act Research Support During the replication of many viruses, hundreds to thousands of protein subunits assemble around the viral nucleic acid to form a protein shell called a capsid. Within their host organism, most viruses form one particular structure with astonishing fide National Institutes of Health 9/01/2009
MCLEAN HOSPITAL CORPORATION, THE $114,155 Trans-NIH Recovery Act Research Support This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov National Institutes of Health 9/28/2009
UNIVERSITY OF MASSACHUSETTS $113,898 Trans-NIH Recovery Act Research Support Antigen processing is an integral part of cell-mediated immune surveillance and responses that involve MHC- restriction and T cell recognition. Processed antigenic peptides, when presented on cell surface by MHC molecules to T cells, serve as identity tag National Institutes of Health 3/15/2011
BROAD INSTITUTE, INC., THE $113,025 Trans-NIH Recovery Act Research Support The goal of our parent R21 project is to create a high-performance, multi-scale, Integrative Genomics Data Viewer (IGV) to support the TCGA project, which displays multiple data types against genomic coordinates with near-immediate response time at all le National Institutes of Health 9/17/2009
FORSYTH DENTAL INFIRMARY FOR CHILDREN $112,825 Trans-NIH Recovery Act Research Support The purpose of this supplemental application is to accelerate the pace and achievement of the goals set forth in the parent grant entitled, Matrix Protein Regulation of Enamel Mineral Formation through 1) the establishment of a new collaboration and 2) by
This spending item is part of a $127,285 allocation. See details
National Institutes of Health 9/01/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $111,686 Trans-NIH Recovery Act Research Support With the aid of this administrative supplement mechanistic studies of coupling reactions of alkyl electrophiles and in particular investigations of stereoselective cross-coupling processes of alkyl electrophiles will be pursued. Enantioselective react National Institutes of Health 9/29/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $111,192 Trans-NIH Recovery Act Research Support Among the myriad protein interaction domains, PDZ domains, (structural domain of 80-90 amino-acids) are one of the most frequently encountered. They are often found in combination with other interaction modules and play a role in establishing cell polarit National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $106,458 Trans-NIH Recovery Act Research Support Higher plants produce a diverse array of complex natural products many of which have potent anti-cancer activity. Unfortunately however the biosynthetic pathways that are responsible for the construction of these plant-derived molecules are not well und National Institutes of Health 7/15/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $105,520 Trans-NIH Recovery Act Research Support Bacterial cell cycle progression and development rely on a backbone of transcription factors and phosphorelay systems to temporally coordinate gene expression with events in the cell. The phosphorelays have been relatively well characterized in the model National Institutes of Health 9/17/2009
BOSTON COLLEGE, TRUSTEES OF $104,970 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Abstract Current estimates place the number of personal variants at approximately 4 million per genome. Given the rapid advances in genome sequencing technologies and the future democratization of human genome sequenci
This spending item is part of a $784,738 allocation. See details
National Institutes of Health 9/30/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $100,760 Trans-NIH Recovery Act Research Support Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms and provide the monomeric precursors required for DNA replication and DNA repair. 1,2 The class I RNRs are composed of two subunits: the alpha-n National Institutes of Health 9/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $100,000 Trans-NIH Recovery Act Research Support The kidney regulates water/salt balance, nitrogenous waste, blood pressure and blood composition. Kidney function is vital to homeostasis of the body fluids. Chronic kidney disease affects one in nine Americans, a similar number are at risk. The heath car National Institutes of Health 9/25/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $100,000 Trans-NIH Recovery Act Research Support This award of $100,000 was for partial funding for a Bruker Biospin 800 MHz solution NMR spectrometer costing $1,050,000. The spectrometer dramatically enhance access to high-field NMR spectrometer time urgently needed for studies of large proteins and pr National Institutes of Health 8/03/2009
MCLEAN HOSPITAL CORPORATION, THE $98,876 Trans-NIH Recovery Act Research Support This is an amended competitive continuation grant of the Udall Parkinson's Disease Research Center of Excellence at Harvard University and McLean Hospital, which is directed by Professor Ole Isacson. The Center performs scientific work on conceptually nov National Institutes of Health 9/28/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $97,684 Trans-NIH Recovery Act Research Support The goals of this study are two-fold: 1) to understand how energy-dependent ATPase enzymes function in bacterial secretion and 2) to elucidate mechanisms of ATPase regulation by accessory proteins. This application will focus on characterizing the biochem National Institutes of Health 7/17/2009
HUMAN SERVICES RESEARCH INSTITUTE $96,686 ?RECOVERY: Increasing Adoption of Patient-Centered Behavioral Health Research by Primary Care and Behavioral Health Providers and Systems??funded through the American Recovery and Reinvestment Act as part of appropriations toward comparative effectiveness
This spending item is part of a $1,944,004 allocation. See details
Substance Abuse and Mental Health Services Administration 7/27/2010
TRI-CITY COMMUNITY ACTION PROGRAM INC $96,573 ARRA - Head Start Cost of Living grant is for 1.84% increase for all staff. Quality Improvement grant is for salary and fringe increases for teaching and transportation staff. Classroom renovations, materials, and furniture will also be purchased with this grant. Administration for Children and Families 8/05/2009
ORGANIX INCORPORATED $96,281 Trans-NIH Recovery Act Research Support The overall scope of our Phase Two SBIR project has been to design, synthesize, and develop novel and patentable 5-HT2C-selective indole derivatives leading to the development of a clinical candidate to treat obesity, and ultimately to the approval of thi National Institutes of Health 1/18/2010
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $94,409 Trans-NIH Recovery Act Research Support The process of DNA replication during S phase of the cell cycle is constantly challenged by the presence of damaged DNA on the replication template. Base lesions in chromosomes can cause DNA polymerase stalling, and if the stalled polymerase is not resolv National Institutes of Health 8/13/2009
CRESS LLC $93,640 Trans-NIH Recovery Act Research Support Research into the properties of children's speech production National Institutes of Health 7/17/2009
CRESS LLC $93,640 Trans-NIH Recovery Act Research Support To hire analysts to examine the data of children's speech development National Institutes of Health 7/17/2009
CRESS LLC $93,640 Trans-NIH Recovery Act Research Support To hire people to perform acoustic analyses of children's speech National Institutes of Health 7/17/2009
CRESS LLC $93,640 Trans-NIH Recovery Act Research Support Ananlysis of children's speech National Institutes of Health 7/17/2009
ACRE FAMILY CHILD CARE, INC. $92,853 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $92,824 Trans-NIH Recovery Act Research Support Large-scale genome sequencing has revealed that some organisms have genomes that encode for an astonishing number of proteins with domains of extremely low sequence complexity. Although the folding and function of these domains is poorly understood, they National Institutes of Health 6/04/2009
VETERANS HEALTH ADMINISTRATION $91,623 Recovery Act Comparative Effectiveness Research - AHRQ This proposed work is responsive to the RFP HS-10-009: Comparative Effectiveness Research to Optimize Prevention and Healthcare Management for the Complex Patient. The proposed work addresses several of the Institute of MedicineG??s (IOMG??s) nat... Show more
This spending item is part of a $377,655 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
BRANDEIS UNIVERSITY $91,268 Trans-NIH Recovery Act Research Support The mechanisms by which animals respond to environmental temperature is not fully understood. C. elegans responds to ambient temperature in a complex, experience-dependent manner. The behavior of C. elegans on a thermal gradient is dependent on its prior National Institutes of Health 8/31/2009
MCLEAN HOSPITAL CORPORATION, THE $90,995 Trans-NIH Recovery Act Research Support Diabetes causes lower extremity problems in a large number of diabetic patients. Peripheral arterial disease (PAD) can affect up to 29% of all diabetic patients while functional changes in the microcirculation are present in the vast majority of them. The
This spending item is part of a $452,400 allocation. See details
National Institutes of Health 8/14/2009
DIGILAB, INC. $90,500 HONEYBEE 963 National Institutes of Health 10/16/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $90,000 Trans-NIH Recovery Act Research Support The experimental aims of the parent award were conceived following the hypothesis that Dm ime4, Drosophila homolog of yeast IME4, that will serve as a stepping stone for the study of this gene in metazoans, had a similar function to that of its yeast coun National Institutes of Health 6/11/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $89,148 Trans-NIH Recovery Act Research Support Our long-term objective for this proposed research is to discover novel treatments for red cell disorders with hemoglobinopathy. In this supplement proposal, we will accelerate and extend the research proposed in the parent grant for the screening small c National Institutes of Health 9/30/2009
BRANDEIS UNIVERSITY $87,264 Trans-NIH Recovery Act Research Support Animal behavior is both stable and plastic. To these ends, molecules and neural circuits respond to environmental changes, both short-term and long-term pertubations. In some cases, the responses maintain a fixed behavior despite a radically altered exter National Institutes of Health 7/15/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $87,028 Trans-NIH Recovery Act Research Support This administrative supplement will enable support of the tuition and stipend of a student in the Computational and Systems Biology (CSB) Ph.D. Program, helping the program to maintain a critical mass of at least 6 students in each entering class. National Institutes of Health 8/03/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $85,764 Trans-NIH Recovery Act Research Support This FlyBase administrative supplemental request addresses three issues facing FlyBase and other Model Organism Databases (MODs). First is the challenge of handling and integrating the growing number and diversity of large-scale data sets being produced b
This spending item is part of a $417,176 allocation. See details
National Institutes of Health 9/30/2009
BROAD INSTITUTE, INC., THE $85,400 Trans-NIH Recovery Act Research Support This proposal is a request for a Recovery Act Administrative Supplement for the grant 1DP2DK083048-01, a Type 1 Diabetes Pathfinder Award. This Supplement is for additional automation equipment in order to perform high-throughput screening. A primary goal National Institutes of Health 2/11/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $85,093 Trans-NIH Recovery Act Research Support The goal of the approved grant is the microbial production of the potent anticancer drug taxol (paclitaxel) and potentially other natural products of the isoprenoid pathway with pharmaceutical properties. This is to be achieved by: (a) identifying the mis
This spending item is part of a $282,087 allocation. See details
National Institutes of Health 6/11/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $85,000 Trans-NIH Recovery Act Research Support This ARRA project is a supplement to ES16313, The Environment as an Experimental Variable to Calibrate Mouse Models of Human Disease. It supported the work of Ms. Ann Wattanawaraporn, a graduate student, who collaborated with Prof. John Groopman of Johns National Institutes of Health 7/01/2010
MASSACHUSETTS, UNIVERSITY OF $84,751 ARRA ? Equipment to Enhance Training for Health Professionals The purpose award is to educate a well-prepared diverse advanced practice nursing (APN) workforce by purchasing equipment to enhance advanced health assessment skills. In particular, the enhancement of skills in cardiac, respiratory, women... Show more Health Resources and Services Administration 8/31/2010
SOUTH MIDDLESEX OPPORTUNITY COUNCIL, INC. $84,422 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
DM-STAT, INC $82,081 Trans-NIH Recovery Act Research Support DM-STAT serves as the Data Coordinating Center (DCC) for the Collaborative Programs of Excellence in Autism (CPEA)/Studies to Advance Autism Research and Treatment(STAART) Networks. The DCC intends to perform the analysis of the primary S002 (Fluoxetine National Institutes of Health 9/26/2009
TRUSTEES OF TUFTS COLLEGE INC $81,594 Trans-NIH Recovery Act Research Support The P41 Tissue Engineering Resource Center (TERC) was initiated in August 2004 after formal review by the NIH and was recently renewed for another five years. The initial focus for TERC (first five years) was on functional tissue engineering achieved thr
This spending item is part of a $153,147 allocation. See details
National Institutes of Health 8/13/2009
AMBERGEN, INC $80,876 Trans-NIH Recovery Act Research Support The overall aim of the project described in the parent proposal and this supplement is to develop a proteome array based platform for the discovery of novel autoantigen biomarkers for autoimmune disease and then implement the biomarkers into commercial au National Institutes of Health 9/21/2009
UNIVERSITY OF MASSACHUSETTS $80,000 Trans-NIH Recovery Act Research Support Title: Ocular Insert for Non-Invasive Sustained Drug Delivery for the Treatment of Glaucoma. Through Phase I and Phase II SBIR Grant Awards, Vista Scientific has developed and combined two unique drug delivery technologies that can resolve several ophth
This spending item is part of a $1,604,601 allocation. See details
National Institutes of Health 9/16/2009
TRUSTEES OF TUFTS COLLEGE INC $80,000 Trans-NIH Recovery Act Research Support The goal of the approved grant is the microbial production of the potent anticancer drug taxol (paclitaxel) and potentially other natural products of the isoprenoid pathway with pharmaceutical properties. This is to be achieved by: (a) identifying the mis
This spending item is part of a $282,087 allocation. See details
National Institutes of Health 6/11/2010
MCLEAN HOSPITAL CORPORATION, THE $79,000 Trans-NIH Recovery Act Research Support We have developed a plan for a NINDS research organization/consortium to develop, characterize and study iPS cell lines for Parkinson's disease (PD). The consortium is organized with several top research teams with both clinical and basic science expertis National Institutes of Health 9/28/2010
BIOMIMETIC SYSTEMS, INC. $77,926 Trans-NIH Recovery Act Research Support The goal of this project is to develop a sonar system that can be used as a mobility aid by the visually impaired. The system will consist of an ultrasonic acoustic source using a waveform that is designed to optimize target discrimination and a pair of m
This spending item is part of a $128,005 allocation. See details
National Institutes of Health 9/01/2009
BRANDEIS UNIVERSITY $77,184 Trans-NIH Recovery Act Research Support The chemistry catalyzed by cytochromes P450 (activation of molecular oxygen to react with organic molecules) is inherently hazardous to the organism, and must be tightly regulated or take place in a controlled environment. Structural and dynamic changes t National Institutes of Health 9/30/2009
TRUSTEES OF TUFTS COLLEGE INC $76,750 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Expansions of simple DNA repeats are implicated in nearly thirty hereditary disorders in humans. This proposal concentrates on molecular mechanisms responsible for repeat expansions. During the previously funded period National Institutes of Health 6/18/2010
BRANDEIS UNIVERSITY $75,600 Trans-NIH Recovery Act Research Support During the replication of many viruses, hundreds to thousands of protein subunits assemble around the viral nucleic acid to form a protein shell called a capsid. Within their host organism, most viruses form one particular structure with astonishing fidel National Institutes of Health 4/27/2010
PHYLONIX PHARMACEUTICALS, INC. $75,518 Trans-NIH Recovery Act Research Support NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l National Institutes of Health 9/18/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $74,312 Trans-NIH Recovery Act Research Support The goal of this supplemental award is to accelerate our progress on understanding how the brain takes incoming visual information and constructs a neuronal representation (pattern of brain activity) used to recognize and remember objects, even though eac National Institutes of Health 9/01/2009
UNIVERSITY OF MASSACHUSETTS $72,971 Trans-NIH Recovery Act Research Support This is a supplement to create a partnership in environmental public health. Within The New England Consortium's hazardous waste worker health and safety training project we will develop a short training curriculum to prepare worker health and safety and National Institutes of Health 9/30/2009
INDEPENDENCE ROUTE DAY CARE $70,840 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $66,153 Trans-NIH Recovery Act Research Support The present grant aims to achieve the following outcomes across the two-year funding period: 1. to evaluate whether Transcranial Direct Current Stimulation (tDCS) should be delivered sequentially or in parallel to motor training, to enhance motor pattern
This spending item is part of a $467,854 allocation. See details
National Institutes of Health 5/06/2009
BROAD INSTITUTE, INC., THE $64,000 Trans-NIH Recovery Act Research Support GenePattern is a freely available computational genomics environment, with over 11,000 users world-wide, that aims to bring advanced mathematical methods and computational algorithms for the analysis of microarray and other genomic data to the research co National Institutes of Health 9/25/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $63,811 Trans-NIH Recovery Act Research Support Plants and animals respond to PAMPs (pathogen-associated molecular patterns) that are indicative of pathogens. Oligogalacturonides (OGs), plant cell wall fragments generated by pathogen polygalacturonases, function as a PAMP in Arabidopsis thaliana. We hy
This spending item is part of a $228,681 allocation. See details
National Institutes of Health 9/09/2009
BETHEL CHILD CARE SERVICES INC $63,381 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
CAMBRIDGE PUBLIC HEALTH COMMISSION $61,928 Trans-NIH Recovery Act Research Support This supplemental funding will provide support for a collaboration between Boston University's Superfund Basic Research Program Research Translation Core and the Cambridge Health Department. The Boston University Superfund Research Program is an interdisc
This spending item is part of a $256,677 allocation. See details
National Institutes of Health 9/10/2009
BRANDEIS UNIVERSITY $61,832 Trans-NIH Recovery Act Research Support Funds were received to purchase an upgrade for a fluorescence microscope to allow real-time imaging in 3 dimensions. A new piezo-electric stage and UV filters witll be purchased to enable the laboratory to examine the positions of fluyorescently labeled National Institutes of Health 12/04/2009
Springwell Inc $61,169 Aging Congregate Nutrition Services for States The Executive Office of Elder Affairs received a grant of $1.4M from the Federal Administration on Aging to provide Congregate Meals. Congregate meals are provided at senior centers and other community based locations. In addition to offering healthy m... Show more
This spending item is part of a $1,403,578 allocation. See details
Administration on Aging 3/18/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $60,684 Trans-NIH Recovery Act Research Support This award is being funded with American Recovery and Reinvestment Act of 2009, as a supplement to the parent grant GM084181-02 Analysis and design of interaction specificity in proteins regulating apoptosis. The objectives of the parent award are to bett National Institutes of Health 4/16/2010
INFOSCITEX CORPORATION $59,823 Trans-NIH Recovery Act Research Support The purpose of the R43 award is to determine the feasibility of creating a device that can be incorporated into the prosthesis to improve the circulation in the residual limbs of persons with amputation resulting from vascular complications. The delivera
This spending item is part of a $199,686 allocation. See details
National Institutes of Health 4/15/2010
TRUSTEES OF TUFTS COLLEGE INC $59,505 Trans-NIH Recovery Act Research Support The proposed study will initiate a new collaboration and advance the theme of our current studies on genetic instability in translocation-related human cancers. There are unstable regions of the human genome that are 'hotspots' for deletions and transloca
This spending item is part of a $178,772 allocation. See details
National Institutes of Health 7/19/2011
BRANDEIS UNIVERSITY $59,345 Trans-NIH Recovery Act Research Support Dyneins are microtubule-based motor enzymes that convert chemical energy into mechanical work. The dynein motors occur either in the cytoplasm, where they mediate retrograde transport, or within the integral structure of cilia and flagella, where they gen National Institutes of Health 9/30/2009
MILLIPORE CORPORATION $58,897 Laboratory Supplies National Institutes of Health 9/28/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $57,445 Trans-NIH Recovery Act Research Support The aim of this project is to understand how bacterial multicomponent monooxygenases activate dioxygen to perform the selective oxidation of hydrocarbons through the synthesis of model compounds and by direct studies of the enzymes. The flagship member of National Institutes of Health 9/18/2009
MYSTIC VALLEY ELDER SERVICES INC $55,472 Aging Congregate Nutrition Services for States The Executive Office of Elder Affairs received a grant of $1.4M from the Federal Administration on Aging to provide Congregate Meals. Congregate meals are provided at senior centers and other community based locations. In addition to offering healthy m... Show more
This spending item is part of a $1,403,578 allocation. See details
Administration on Aging 3/18/2009
SOMERVILLE MENTAL HEALTH ASSOCIATION INC $55,286 ARRA - Head Start ARRA Cost-of-Living Adjustment (COLA) increase of 1.84% in the amount of $16,376 and Quality Improvement funds of $38,910, consistent with the provisions of Section 640(a)(5) of the Head Start Act. Administration for Children and Families 6/30/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $54,400 Trans-NIH Recovery Act Research Support Title: Polymeric Matrices With Defined Cell Adhesion The objective of this administrative supplement request is to accelerate the tempo of scientific research funded under the MERIT award. The long-term objective of this project is to develop material s National Institutes of Health 3/09/2010
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $54,000 Trans-NIH Recovery Act Research Support As a pediatric hematologist, I feel a great need to understand the mechanisms behind the dysregulation of differentiation and proliferation that occur in certain acquired and congenital aplastic anemias and leukemias found in my patient population. The mo National Institutes of Health 12/18/2009
MCLEAN HOSPITAL CORPORATION, THE $53,917 Trans-NIH Recovery Act Research Support This is a first resubmission of a K23-Mentored Patient-Oriented Research Career Development Award application entitled MRS Studies of Glutamate and GABA in Bipolar Disorder. The candidate's background is in postmortem studies of cellular abnormalities in National Institutes of Health 3/12/2010
REGIS COLLEGE $53,530 ARRA - Scholarships for Disadvantaged Students ARRA- Scholorships for Disadvantaged Students(SDS) The ARRA Scholarships for Disadvantaged Students (ARRA SDS) grant award provides scholarships to financially needy undergraduate nursing students from disadvantaged backgrounds. Many of these students ar... Show more Health Resources and Services Administration 6/14/2010
HARVARD VANGUARD MEDICAL ASSOCIATES, INC. $52,238 Although the incidence of ductal carcinoma in situ (DCIS) has risen dramatically within the last 20 years, the long term consequences of different DCIS treatment strategies are not well understood. Treatment options for DCIS include type of surgery (lumpe
This spending item is part of a $3,040,076 allocation. See details
Agency for Healthcare Research and Quality 7/13/2010
INFOSCITEX CORPORATION $51,348 Trans-NIH Recovery Act Research Support This grant provided a summer research experience(s) for 9 college students and 1 science educator in health?related scientific research. The college students were: Meixin Wang, Prasant Varghese, Debra Leong, Ranjan Upadhyay, David Shiovitz, Jennifer Wang, National Institutes of Health 6/08/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $50,000 Trans-NIH Recovery Act Research Support The overall goal of this supplement and the parent award is to understand how cells cooperate when they share secreted products. Saccharomyces cerevisiae cells secrete acid phosphatase to break down unimportable organic phosphates and secrete invertase to National Institutes of Health 4/09/2010
MCLEAN HOSPITAL CORPORATION, THE $50,000 Trans-NIH Recovery Act Research Support This application proposes to study a large cohort of children with autism using a multidisciplinary analytic approach in order to identify biological signatures that define distinct phenotypes of autism. We propose that subtypes will be identifiable on th
This spending item is part of a $2,828,090 allocation. See details
National Institutes of Health 9/23/2009
Massachusetts Association For The Education of Young Childre $50,000 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
PHYLONIX PHARMACEUTICALS, INC. $49,280 Trans-NIH Recovery Act Research Support NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l National Institutes of Health 7/11/2009
PHYLONIX PHARMACEUTICALS, INC. $49,280 Trans-NIH Recovery Act Research Support NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l National Institutes of Health 6/05/2009
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $47,096 Trans-NIH Recovery Act Research Support This ARRA award is a supplement to support summer stipends for two undergraduate research students who will receive training in biomedical research while contributing to ongoing research for the parent project. National Institutes of Health 7/17/2009
BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. $47,096 Trans-NIH Recovery Act Research Support This ARRA award is a supplement to support summer stipends for two undergraduate research students who will receive training in biomedical research while contributing to ongoing research for the parent grant. National Institutes of Health 7/17/2009
COVARIS, INC. $46,125 Instrumentation and supplies ordered: QTY 1 S2 High Performance Ultrasonicator, QTY 1 S2 DNA kit, QTY 1Centrifuge Adaptor for microTUBES, qty 1 CH01 Recirculating Chiller, QTY 1 installation and 1/2 day training per quote # QTE1000892B Health and Human Services, Department of 8/10/2010
ABT ASSOCIATES INC. $45,986 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Despite the fact that contraceptives have the potential to nearly eliminate pregnancy and sexually transmitted diseases (STDs), data from the 2002 National Survey of Family Growth show that almost half the pregnancies
This spending item is part of a $170,262 allocation. See details
National Institutes of Health 7/24/2009
Somerville Cambridge Elder Services Corp $44,410 Aging Congregate Nutrition Services for States The Executive Office of Elder Affairs received a grant of $1.4M from the Federal Administration on Aging to provide Congregate Meals. Congregate meals are provided at senior centers and other community based locations. In addition to offering healthy m... Show more
This spending item is part of a $1,403,578 allocation. See details
Administration on Aging 3/18/2009
ISOMICS, INC $43,600 Trans-NIH Recovery Act Research Support The Neuroimage Analysis Center (NAC), a national resource center, is developing algorithms and image analysis software tools for improving our understanding of brain diseases and enabling innovative treatments. The focus of this competitive renewal is the
This spending item is part of a $1,805,902 allocation. See details
National Institutes of Health 9/17/2009
CAMBRIDGESOFT CORPORATION $39,888 Procure through purchase/license new commercial off the shelf (COTS) software to integrate with the Cambridge Soft software utilized for the collection of all data generated on Chemical Biology Consortium projects that are conducted within the NCI, at SAI
This spending item is part of a $2,000,000 allocation. See details
National Institutes of Health 11/23/2009
BOSTON COLLEGE, TRUSTEES OF $38,986 Trans-NIH Recovery Act Research Support The parent grant, entitled G?Accurate protein structural comparison by TOPOFITG? and aimed to continue the development of the PIG??s package for 3D protein structure alignment called TOPOFIT. The significance of the project was recognized by the NLM/
This spending item is part of a $118,986 allocation. See details
National Institutes of Health 8/24/2010
HIGH PINE ASSOCIATES LLC $37,650 BAH will provide technical assistance to the Beacon Community Cooperative Agreement awardees and ONC as together they lead the development of a regional healthcare strategy for Health Information Technology (HIT) ?enabled cost and quality performance impr
This spending item is part of a $11,933,252 allocation. See details
Program Support Center 9/30/2010
CONCORD CONSORTIUM INC $37,445 Trans-NIH Recovery Act Research Support The mammalian genome is a dynamic system that varies spatially in its organization and expression and temporally in its evolution and inheritance. Using a team of computational biologists, molecular biologists and geneticists, we are studying genome dynam
This spending item is part of a $725,671 allocation. See details
National Institutes of Health 2/19/2010
FORSYTH DENTAL INFIRMARY FOR CHILDREN $36,507 Trans-NIH Recovery Act Research Support Despite many studies that have aimed to alleviate the effects of periodontal and endodontic disease there is still an urgent need to improve the oral health of those suffering from oral infectious or inflammatory diseases. Such translational application o
This spending item is part of a $592,990 allocation. See details
National Institutes of Health 4/28/2011
DM-STAT, INC $36,496 Trans-NIH Recovery Act Research Support a) DC-8484958: All MONICA Fetal Heart Rate Monitors have been purchased, tested, and distributed to each of the four clinical sites. Study personnel at two of the clinical sites, Spirit Lake and Sanford Health, have been trained in using the MONICA to c
This spending item is part of a $1,165,393 allocation. See details
National Institutes of Health 9/28/2009
Minuteman Senior Services $35,473 Aging Congregate Nutrition Services for States The Executive Office of Elder Affairs received a grant of $1.4M from the Federal Administration on Aging to provide Congregate Meals. Congregate meals are provided at senior centers and other community based locations. In addition to offering healthy m... Show more
This spending item is part of a $1,403,578 allocation. See details
Administration on Aging 3/18/2009
BRANDEIS UNIVERSITY $35,000 Trans-NIH Recovery Act Research Support Essential divalent transition metals such as zinc, copper, and iron play important structural and catalytic roles in over 300 proteins. However, these and other transition metals also pose a potential threat to an organism. Left unchecked these metals can National Institutes of Health 8/27/2010
BROAD INSTITUTE, INC., THE $35,000 Trans-NIH Recovery Act Research Support Unfortunately, most individuals do not express protective HLA class I alleles such as B57 and B27, and are thus unable to control viral replication and disease progression. Understanding the mechanisms of this control might facilitate instilling these pr
This spending item is part of a $1,464,387 allocation. See details
National Institutes of Health 8/02/2010
BRANDEIS UNIVERSITY $34,906 Trans-NIH Recovery Act Research Support Rett Syndrome is a devastating developmental disorder due in most cases to mutation of the gene Mecp2. Affected individuals lose or fail to develop many normal language, motor and cognitive abilities. Mutant mice lacking part or all of the gene recapitula National Institutes of Health 7/19/2009
Elder Baypath Svcs $34,495 Aging Congregate Nutrition Services for States The Executive Office of Elder Affairs received a grant of $1.4M from the Federal Administration on Aging to provide Congregate Meals. Congregate meals are provided at senior centers and other community based locations. In addition to offering healthy m... Show more
This spending item is part of a $1,403,578 allocation. See details
Administration on Aging 3/18/2009
TRUSTEES OF TUFTS COLLEGE INC $34,016 Trans-NIH Recovery Act Research Support Critical sized bone defects caused by injury, disease or congenital malformations, remain a challenging problem in orthopedic medicine. Current options to restore full function to such bone defects are limited due to slow rates of regeneration of native National Institutes of Health 6/05/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $34,000 Trans-NIH Recovery Act Research Support The Harvard University Center for AIDS Research (HU CFAR) represents each of the Harvard affiliated schools and hospitals, including Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, Children's Hospital Boston, the Immune Disease Institu
This spending item is part of a $134,000 allocation. See details
National Institutes of Health 8/16/2010
LAHEY CLINIC, INC. $33,482 Trans-NIH Recovery Act Research Support These studies will integrate the expertise of clinicians, basic scientists, and clinical researchers and have potential to identify A20 based therapies useful for the prevention or treatment of liver graft dysfunction, identify and devise treatment strate National Institutes of Health 9/30/2010
TRUSTEES OF TUFTS COLLEGE INC $33,249 Trans-NIH Recovery Act Research Support Poor adherence with prescription medications is ubiquitous and costly. Physicians' assessments of patients' adherence are inaccurate, which makes it attractive to use pharmacy claims to identify nonadherence. But research clearly shows that simply giving
This spending item is part of a $1,240,552 allocation. See details
National Institutes of Health 3/24/2011
NEW ENGLAND RESEARCH INSTITUTES, INC. $33,006 Trans-NIH Recovery Act Research Support This project is designed to complete the scientific planning and administrative activities that are required to conduct a clinical trial on the efficacy of lifestyle intervention to treat obese men with erectile dysfunction (ED). ED is a significant publ
This spending item is part of a $726,805 allocation. See details
National Institutes of Health 9/29/2009
BEDFORD VA RESEARCH CORPORATION, INC., THE $32,932 Trans-NIH Recovery Act Research Support Nonpayment for Preventable Complications: Impact on Hospital Practices and Health Our long-term goal is to assess the overall impact of Medicare?s new policy of no longer paying hospitals for treating certain healthcare associated infections (HAIs) that
This spending item is part of a $447,156 allocation. See details
National Institutes of Health 7/22/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $31,030 Trans-NIH Recovery Act Research Support An Administrative Supplement is requested for NCI grant R01-CA103146 Chemistry and Biology of Deoxyribose Oxidation. This and several other NIH grants involve quantification of molecular damage products using sensitive chromatography-coupled mass spectro National Institutes of Health 9/01/2009
Springwell Inc $30,114 Aging Home-Delivered Nutrition Services for States The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community. This g... Show more
This spending item is part of a $690,992 allocation. See details
Administration on Aging 3/18/2009
BOSTON COLLEGE, TRUSTEES OF $30,048 Trans-NIH Recovery Act Research Support The administrative supplement is for funds to increase the tempo of summer research in several key areas of parent NIH DP1OD003312. In particular, this grant is for hiring undergraduate students during summer months. During the summer 2009, we hired 10 National Institutes of Health 7/17/2009
MASSACHUSETTS EHEALTH COLLABORATIVE, INC $29,750 BAH will provide technical assistance to the Beacon Community Cooperative Agreement awardees and ONC as together they lead the development of a regional healthcare strategy for Health Information Technology (HIT) ?enabled cost and quality performance impr
This spending item is part of a $11,933,252 allocation. See details
Program Support Center 9/30/2010
Oxford Cryosystems Inc $29,036 Trans-NIH Recovery Act Research Support Title: Macromolecular Crystallography at the National Synchrotron Light Source. Description: We are constructing an integrated facility at beamline X26-C of the National Synchrotron Light Source (NSLS) for single crystal X-ray diffraction and spectrosco
This spending item is part of a $853,840 allocation. See details
National Institutes of Health 8/13/2009
MASSACHUSETTS EHEALTH COLLABORATIVE, INC $28,651 Booz Allen will assist AHRQ to develop an operations plan for program management of the HITRC. Preliminary steps in developing the Operations Plan include development of a Strategic Plan and documenting data, reporting, and system (functional) requirement
This spending item is part of a $567,455 allocation. See details
Agency for Healthcare Research and Quality 1/04/2010
BRANDEIS UNIVERSITY $28,000 Trans-NIH Recovery Act Research Support Our long-term goal is to gain a highly mechanistic understanding of how the actin cytoskeleton directs cell polarity and cell morphogenesis. All living cells have internal and external structures tailored to and critical for their distinctive physiologica National Institutes of Health 8/31/2010
MYSTIC VALLEY ELDER SERVICES INC $27,706 Aging Home-Delivered Nutrition Services for States The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community. This g... Show more
This spending item is part of a $690,992 allocation. See details
Administration on Aging 3/18/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $27,000 Trans-NIH Recovery Act Research Support The study of glycosaminoglycan (GAG) degrading enzymes such as heparinases chondroitinases exolytic D4 5-glycuronidase and sulfatases require significant of purified enzymes. These enzymes can be extracted from natural sources or can be produced by re National Institutes of Health 3/12/2010
BIOSENSE TECHNOLOGIES, INC. $26,054 Trans-NIH Recovery Act Research Support A low-cost optical-based instrument is proposed for the real-time diagnosis of urinary tract infections (UTI) at the point of care. A primary innovation of the instrument is the incorporation of inexpensive mass produced optical components such as high po National Institutes of Health 3/05/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $25,905 Trans-NIH Recovery Act Research Support Our goal is to test the expression output of tens of thousands of candidate enhancers in a single experiment. This can be of great use in testing predicted candidate enhancers across the genome arising from our chromatin work in the context of ENCODE and
This spending item is part of a $372,834 allocation. See details
National Institutes of Health 8/06/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $25,878 Trans-NIH Recovery Act Research Support This grant provided a summer research experience(s) for one science educator in health-related scientific research.
This spending item is part of a $39,019 allocation. See details
National Institutes of Health 6/01/2009
CAMBRIDGE PUBLIC HEALTH COMMISSION $25,000 Trans-NIH Recovery Act Research Support Our goals for this supplement are to 1) engage in a public awareness campaign about the Community Connect to Research resource, 2) gather feedback on its design, content, and usefulness, 3) expand and enhance it with additional content, and 4) ultimately,
This spending item is part of a $596,314 allocation. See details
National Institutes of Health 9/24/2009
CHILD CARE RESOURCE CENTER INC $25,000 ARRA - Prevention and Wellness--State Territories and Pacific Islands The Communities Putting Prevention to Work initiative supports states in promoting wellness and preventing chronic disease through statewide policies and environmental change to create healthier communities. Nutrition Componen... Show more
This spending item is part of a $949,797 allocation. See details
Centers for Disease Control and Prevention 2/04/2010
BELMONT INSTRUMENT CORPORATION $24,876 FMS 2000, 1000 ML, FMS Model 2516 Universal 3-Bag Spike Disposable National Institutes of Health 8/11/2010
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $22,512 Trans-NIH Recovery Act Research Support This grant provided a summer research experience(s) for __three____ (insert X number of high school student(s) college student(s) science educator(s) etc.) in health-related scientific research. National Institutes of Health 6/16/2009
Somerville Cambridge Elder Services Corp $21,864 Aging Home-Delivered Nutrition Services for States The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community. This g... Show more
This spending item is part of a $690,992 allocation. See details
Administration on Aging 3/18/2009
METASYSTEMS GROUP, INC $21,100 Software Upgrade MC-167 National Institutes of Health 9/25/2009
CAMBRIDGE PUBLIC HEALTH COMMISSION $20,017 Trans-NIH Recovery Act Research Support Our goals for this supplement are to 1) engage in a public awareness campaign about the Community Connect to Research resource, 2) gather feedback on its design, content, and usefulness, 3) expand and enhance it with additional content, and 4) ultimately,
This spending item is part of a $596,314 allocation. See details
National Institutes of Health 9/24/2009
INSTITUTE FOR HEALTH METRICS CORPORATION $19,992 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This application addresses broad challenge area (05) Comparative Effectiveness Research and specific challenge topic, 05-CA-104: Comparative Effectiveness Research on Cancer Treatment. Broad Objectives: The long-term
This spending item is part of a $247,168 allocation. See details
National Institutes of Health 9/20/2011
BOSTON COLLEGE, TRUSTEES OF $18,692 Trans-NIH Recovery Act Research Support The Patient Navigator supplement is an addition to the project staff for the UMB/DF-HCC U56 pilot entitled, Cancer Screening among Latinos in Churches. This community-based outreach pilot is funded by the U56 Developmental Core and began its final year of
This spending item is part of a $304,991 allocation. See details
National Institutes of Health 7/01/2009
METROWEST YMCA, INC. $18,217 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
Minuteman Senior Services $17,466 Aging Home-Delivered Nutrition Services for States The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community. This g... Show more
This spending item is part of a $690,992 allocation. See details
Administration on Aging 3/18/2009
BRANDEIS UNIVERSITY $17,453 Trans-NIH Recovery Act Research Support Ras proteins are crucial regulators of cell proliferation, survival and differentiation. Aberrant activation of Ras proteins, either by Ras mutations or by altering genes that directly or indirectly regulate Ras, is common in both solid tumors and hematol National Institutes of Health 6/01/2009
BRANDEIS UNIVERSITY $17,452 Trans-NIH Recovery Act Research Support The sympathetic nervous system innervates a number of targets, including the heart, and sympathetic activity is a critical regulator of cardiac function. Sympathetic neurons form noradrenergic synapses onto heart cells resulting in excitation of myocyte f National Institutes of Health 7/16/2009
BROAD INSTITUTE, INC., THE $17,375 Trans-NIH Recovery Act Research Support Type 2 diabetes (T2D) shows complex inheritance, indicating a causal role for multiple inherited DNA variants. Genome wide association studies (GWAS) have now mapped over 20 novel loci where common variants are associated with risk of T2D. Despite this pr
This spending item is part of a $2,200,000 allocation. See details
National Institutes of Health 9/30/2010
Elder Baypath Svcs $16,982 Aging Home-Delivered Nutrition Services for States The Executive Office of Elder Affairs received a grant of $690,992 from the Administration on Aging to provide home delivered meals to low income elders. These meals will help elders remain healthy, independent, and active in their community. This g... Show more
This spending item is part of a $690,992 allocation. See details
Administration on Aging 3/18/2009
BRANDEIS UNIVERSITY $16,773 Trans-NIH Recovery Act Research Support Many middle-aged and older adults believe as they age that memory declines are inevitable and there is little that can be done. Such beliefs of low self-efficacy and limited control over memory aging are associated with poorer performance on a wide range National Institutes of Health 8/04/2009
ZOLL MEDICAL CORPORATION $15,964 ZOLL M Series ACLS Defibrillator, P/N 40610711100123010 Indian Health Service 8/31/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $15,582 Trans-NIH Recovery Act Research Support Herpesvirues are a significant cause of disease in the human population. Following initial acute infection, herpesvirueses establish latency and the viral DNA is maintained in cells. Murine gammaherpesvirus-68 (MHV-68) is used as a model to study the hu National Institutes of Health 6/18/2009
Concord Children's Center, Inc. $15,000 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
LOWELL, CITY OF (INC) $14,981 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
VANASSE HANGEN BRUSTLIN, INC. $14,750 ARRA Health Center Integrated Services Development Initiative[g1] In 2008, Dorchester House Multi-Service Center (DHMSC) grew by 8% the number of patient visits to the health center for primary care services alone. Current trends in the growth of our neighborhood-?-?s low-income population, the econ... Show more
This spending item is part of a $7,024,029 allocation. See details
Health Resources and Services Administration 10/29/2009
NEWTON COMMUNITY SERVICE CENTER INC $13,245 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $9,744 Trans-NIH Recovery Act Research Support This grant provided a summer research experience for one college student in health-related scientific research. National Institutes of Health 7/30/2010
COMMUNITIES UNITED INC $9,695 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MALDEN SCHOOL DISTRICT $9,450 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
BRANDEIS UNIVERSITY $9,311 Trans-NIH Recovery Act Research Support Bone morphogenetic proteins (BMPs) have been implicated as control factors in many different developmental transitions. During nervous system development BMPs regulate neural induction, formation of the neural crest, and the development of both neurons a National Institutes of Health 7/09/2009
WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH $8,190 Trans-NIH Recovery Act Research Support Previous research published in this laboratory in Cell in 2008 (McAllister, SS et al., Cell 133:994-1005) described a process that was termed G?systemic instigationG? in which a vigorously growing G?instigatingG? tumor implanted in one side of a mouse was National Institutes of Health 5/29/2009
MALDEN YOUNG MEN'S CHRISTIAN ASSOCIATION, THE $6,765 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
Welcome Project Inc $6,671 Trans-NIH Recovery Act Research Support The Tufts CTSI, created in May 2008 (UL1 RR025752, PI: Dr. Harry P. Selker) includes over 40 institutions and organizations throughout Massachusetts and extends regionally to Maine. One of the core components of the Tufts CTSI is the Novel Methods and Pil
This spending item is part of a $399,965 allocation. See details
National Institutes of Health 9/25/2009
ELIZABETH PEABODY HOUSE ASSOCIATION INC $6,631 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
FRAMINGHAM, TOWN OF $6,600 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
BROAD INSTITUTE, INC., THE $5,712 Trans-NIH Recovery Act Research Support This study seeks to elucidate the mechanistic basis of immune responses to factor VIII (FVIII) in some but not all hemophilia A (HA) patients and the increased risk of HA patients with black African ancestry for developing that complication following ther
This spending item is part of a $6,507,463 allocation. See details
National Institutes of Health 9/24/2009
CAMBRIDGE COMMUNITY CENTER $5,066 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
YOUNG WOMEN'S CHRISTIAN ASSOCIATION OF MALDEN INC $4,356 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
COMMUNITY ART CENTER INC, THE $2,296 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
WOBURN COUNCIL OF SOCIAL CONCERN, INC. $2,074 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MYSTIC LEARNING CENTER $1,861 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MARGARET FULLER NEIGHBORHOOD HOUSE INC $1,425 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
TRI-CITY COMMUNITY ACTION PROGRAM INC $1,260 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $549 Trans-NIH Recovery Act Research Support This administrative supplement will support ongoing research undertaken by Dr. Elba Serrano's NMSU team of students and professional scientists as part of the current Cell Decision Process award. The long term goal of this research is to uncover and mode
This spending item is part of a $228,516 allocation. See details
National Institutes of Health 9/25/2009
CAMBRIDGEPORT CHILD CARE, INC. $204 ARRA Child Care and Development Block Grant The Child Care Development Fund assists low-income families, families receiving temporary public assistance, and those transitioning from public assistance in obtaining child care so they can work or attend training/education. The ARRA Child Care Develop
This spending item is part of a $23,966,942 allocation. See details
Administration for Children and Families 4/09/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $0 Trans-NIH Recovery Act Research Support The main approach outlined in the original application was to enhance the specificity of tumor targeting by designing mechanisms to amplify the targeting. We believe that this is still an approach unique to us in the nanobiotechnology research arena. This
This spending item is part of a $569,049 allocation. See details
National Institutes of Health 8/31/2009
MASSACHUSETTS INSTITUTE OF TECHNOLOGY $0 Trans-NIH Recovery Act Research Support We have requested supplemental funding for the multidisciplinary and highly successful Center for Cancer Nanotechnology of Excellence at MIT and Harvard. Our CCNE focuses on 5 innovative Research Projects. Project 1 (Langer, Farokhzad) investigates novel
This spending item is part of a $200,001 allocation. See details
National Institutes of Health 9/15/2009
MCLEAN HOSPITAL CORPORATION, THE $0 Trans-NIH Recovery Act Research Support Relative neuronal vulnerability is a universal yet poorly understood feature of neurodegenerative diseases. In Parkinson's disease (PD), dopaminergic (DA) neurons in the substantia nigra (SN; A9) are particularly vulnerable, whereas adjacent DA neurons wi
This spending item is part of a $158,000 allocation. See details
National Institutes of Health 6/01/2009
MA ST DEPARTMENT OF REVENUE -$476,276 Child Support Enforcement 2011 OCSE Administration for Children and Families 1/24/2011