Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Hamilton County, Ohio, funds by Health and Human Services, Department of

Listing $136,827,087.99 in stimulus funds from Health and Human Services, Department of for Hamilton

Note: For some programs where states do not report where money will be distributed across the state, we do not have the allocation for individual counties. Those programs include: Medicaid, unemployment benefits and food stamps. Those amounts are included in the totals for where the state agency receiving that money is located.

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Description Federal Dept./Agency Date
CHILDREN'S HOSPITAL MEDICAL CENTER $9,702,077 Recovery Act Comparative Effectiveness Research - AHRQ EHRs have the potential to anchor a learning healthcare system where each clinical encounter is an opportunity to learn and to improve clinical outcomes. We propose to link EHRs to disease-specific registries in a distributed network of pediatric... Show more
This spending item is part of a $11,743,165 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
GREATER CINCINNATI HEALTH BRIDGE, INC $8,611,532 ARRA - Health Information Technology - Beacon Communities The purpose of the Beacon Community Cooperative Agreement Program is to provide funding to communities to build and strengthen their health information technology (health IT) infrastructure and exchange capabilities to demonstrate the vision o... Show more
This spending item is part of a $13,775,630 allocation. See details
Health and Human Services, Department of 9/02/2010
UNIVERSITY OF CINCINNATI $8,439,998 Trans-NIH Recovery Act Research Support The Medical Sciences Building (MSB) animal facility at the University of Cincinnati was constructed 35 years ago to house primarily large-animal species. MSB is currently unable to meet the present and future needs for bench and translational research uti National Institutes of Health 3/04/2010
County of Hamilton $7,000,000 ARRA Child Care and Development Block Grant $59,245,395 of the ARRA Discretionary funds will be spent during State Fiscal Year 2010 to stabilize the subsidized child care budget thus permitting the continuation of service to existing families. $5,620,429 of the ARRA Targeted Funds for Quality Exp
This spending item is part of a $68,140,840 allocation. See details
Administration for Children and Families 4/09/2009
GREATER CINCINNATI HEALTH BRIDGE, INC $6,295,119 ARRA - Health Information Technology Extension Program HealthBridge is a non-profit health information exchange organization (HIO) that serves a tri-state region of Ohio, Kentucky and Indiana. HealthBridge has assembled a network of clinical, technology and quality improvement leaders who will establ... Show more
This spending item is part of a $10,821,318 allocation. See details
Health and Human Services, Department of 2/08/2010
UNIVERSITY OF CINCINNATI $4,932,531 Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation. See details
National Institutes of Health 9/14/2009
UNIVERSITY OF CINCINNATI $4,819,500 National Center for Research Resources, Recovery Act Construction Support The Department of Environmental Health at the University of Cincinnati is a world leader in environmental and occupational health, with over $22M in external research in 2008. The building that houses this department is showing... Show more National Institutes of Health 1/07/2010
HAMILTON, COUNTY OF $4,002,564 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work WeTHRIVE! Community Wellness in Action Hamilton County, Ohio The Communities Putting Prevention to Work (CPPW) initiative will create county wide policy and environmental change to support he... Show more
This spending item is part of a $6,744,040 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
CINCINNATI-HAMILTON COUNTY COMMUNITY ACTION AGENCY $2,883,960 ARRA - Community Services Block Grant This fund may be used for reduction of poverty, the revitalization of low-income communities, and the empowerment of low income families and individuals in rural and urban areas to become fully self-sufficient. The Award amount has reduced from $38,976,10
This spending item is part of a $38,857,606 allocation. See details
Administration for Children and Families 4/10/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $2,311,874 ARRA - Health Information Technology - Beacon Communities The purpose of the Beacon Community Cooperative Agreement Program is to provide funding to communities to build and strengthen their health information technology (health IT) infrastructure and exchange capabilities to demonstrate the vision o... Show more
This spending item is part of a $13,775,630 allocation. See details
Health and Human Services, Department of 9/02/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $1,813,081 Trans-NIH Recovery Act Research Support The long term objective of this proposal is to conduct a NexGen RNA-Seq based dissection of the gene expression program driving kidney development. The central thesis is straightforward. We propose to define, in a sensitive and quantitative manner, all o National Institutes of Health 9/29/2010
HEALTH IMPROVEMENT COLLABORATIVE OF GREATER CINCINNATI, INC. $1,679,678 ARRA - Health Information Technology - Beacon Communities The purpose of the Beacon Community Cooperative Agreement Program is to provide funding to communities to build and strengthen their health information technology (health IT) infrastructure and exchange capabilities to demonstrate the vision o... Show more
This spending item is part of a $13,775,630 allocation. See details
Health and Human Services, Department of 9/02/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $1,580,324 Trans-NIH Recovery Act Research Support We seek to integrate our molecular investigations with other clinical and pathologic outcome variables that are important in pediatric EE. In Aim 1, we will develop a local internet based registry of subjects with EE to capture defined clinical, pathologi National Institutes of Health 9/29/2009
UNIVERSITY OF CINCINNATI $1,509,480 Trans-NIH Recovery Act Research Support This application addresses one of the five thematic areas in the RFA-OD-10-005: Focusing on Global Health. Electronic waste (e-waste) has become a global environmental health problem because of its huge amount of production worldwideG??G??approximately 20
This spending item is part of a $1,722,932 allocation. See details
National Institutes of Health 9/30/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $1,416,666 Trans-NIH Recovery Act Research Support Our hypothesis is that by expanding our nascent Neuro-Oncology research program, we will form a Core that will lead to a better understanding the biology of pediatric brain tumors. We will use funds from this P30 to recruit and support new assistant prof National Institutes of Health 9/29/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $1,389,508 Trans-NIH Recovery Act Research Support This two-year study aims to explore the effects of prenatal and postnatal exposure to common insecticides (organophosphates and pyrethroids) by assessing neurobehavior during the newborn period and through age 4 years among an established 400-person cohor
This spending item is part of a $1,495,767 allocation. See details
National Institutes of Health 9/19/2009
UNIVERSITY OF CINCINNATI $1,349,819 Trans-NIH Recovery Act Research Support Despite increasing recognition that BPA has harmful effects on the reproductive, nervous and immune systems. While higher urine BPA concentrations are associated with cardiovascular disease in humans, the effect(s) of BPA at environmentally relevant conce National Institutes of Health 9/30/2009
NEIGHBORHOOD HEALTH CARE, INC. $1,138,265 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Project to remove infrastructure barriers to patient access, quality of care, health center efficiency and productivity. Seven new exam rooms have been added to increase patient flow and provider productivity as we... Show more Health Resources and Services Administration 6/25/2009
MT AUBURN HEALTH CENTER $1,138,265 ARRA Health Center Integrated Services Development Initiative[g1] Capital Improvement Project to remove infrastructure barriers to patient access, quality of care, health center efficiency and productivity. Seven new exam rooms have been added to increase patient flow and provider productivity as we... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF CINCINNATI $1,111,765 Trans-NIH Recovery Act Research Support Our objective is to understand the mechanisms by which the NHE1 Na/H exchanger and the AE1, AE2, AE3, and PAT1 (Slc4a1-3 and Slc26a6) Cl/HCO3 exchangers affect cardiac Ca handling, contractility, and metabolism. These acid-base transporters comprise a rob National Institutes of Health 8/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $1,091,071 Trans-NIH Recovery Act Research Support This award addresses an important concern for women's health, i.e. infertility. Despite significant developments in IVF technology, the pregnancy success rate remains low because of higher incidence of implantation failure and unexplained pregnancy loss. National Institutes of Health 8/10/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $1,000,000 Trans-NIH Recovery Act Research Support Juvenile idiopathic arthritis (JIA) is the most common autoimmune rheumatic disease of childhood. JIA is a disabling disease representing a series of childhood arthropathies that are defined based largely on clinical features. For the past thirty years, National Institutes of Health 9/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $999,543 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (03) Biomarker Discovery and Validation and specific Challenge Topic Identify and validate clinically relevant, quantifiable biomarkers of diagnostic and therapeutic responses for blood, vascular, cardiac, a National Institutes of Health 9/21/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $994,437 Trans-NIH Recovery Act Research Support As part of the P30 Asthma Research Core, we will use the monies to support additional new faculty in Asthma Research through a Pilot grant program. We will award two grants of $50,000 each year for two years. Recipients of a pilot grant in year 1 can ap National Institutes of Health 9/18/2009
The Young Men's Christian Association of Greater Cincinnati $990,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work WeTHRIVE! Community Wellness in Action Hamilton County, Ohio The Communities Putting Prevention to Work (CPPW) initiative will create county wide policy and environmental change to support he... Show more
This spending item is part of a $6,744,040 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $950,772 Trans-NIH Recovery Act Research Support This contract will test the following 3 hypotheses: 1. IL-4 and IL-13 induction of AHR is completely accounted for by its effects on smooth muscle and epithelial cells. 2. Induction of airway remodeling by IL-4 and IL-13 is primarily accounted for by th National Institutes of Health 8/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $934,476 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work WeTHRIVE! Community Wellness in Action Hamilton County, Ohio The Communities Putting Prevention to Work (CPPW) initiative will create county wide policy and environmental change to support he... Show more
This spending item is part of a $6,744,040 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
CINCINNATI-HAMILTON COUNTY COMMUNITY ACTION AGENCY $922,189 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and pay for hig
This spending item is part of a $1,829,607 allocation. See details
Administration for Children and Families 6/25/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $895,078 Trans-NIH Recovery Act Research Support The Aims of the project are: 1. Determine if Notch signaling regulates semilunar valve cell lineage differentiation and leaflet stratification in vivo. 2. Dissect the Notch signaling pathway and intersecting pathways in aortic valve progenitor cell li National Institutes of Health 6/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $866,331 Trans-NIH Recovery Act Research Support Declining immune function is well described in the elderly, and contributes significantly to increased risk and severity of infection, impaired responses to vaccination, and poorer control of cancer. Infections with several pathogens, whether viral (e.g.,
This spending item is part of a $945,026 allocation. See details
National Institutes of Health 9/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $836,262 Trans-NIH Recovery Act Research Support This Challenge Research project will undertake 1) a mouse genome-wide shRNA library screen to identify genes and associated gene networks inducing or inhibiting goblet cell differentiation and mucous hypersecretion, and 2) an extensive small molecule comp National Institutes of Health 9/17/2009
HEALTHCARE CONNECTION, INC.,THE $831,455 ARRA Health Center Integrated Services Development Initiative[g1] ARRA- Capital Improvement Program. The Healthcare Connections (HCC) lacks infrastructure for improved service delivery and efficiency. The goal is to utilize current technology to its fullest potential. This will position the organizat... Show more Health Resources and Services Administration 6/25/2009
CHILD FOCUS, INC. $818,113 ARRA - Head Start This award provides for Head Start Expansion to serve 66 children. 54 children are served in a center-based program and 12 are served in a home-based setting. This program promotes healthy development and school readiness for children ages 3 to 5 years Administration for Children and Families 9/16/2009
UNIVERSITY OF CINCINNATI $785,000 Trans-NIH Recovery Act Research Support The goal of this grant proposal is to use newly developed transgenic mouse models to 1) elucidate the role of keratocan-expressing cell lineage in corneal morphogenesis during development and in the maintenance of corneal stromal homeostasis in adult and National Institutes of Health 8/11/2009
UNIVERSITY OF CINCINNATI $765,740 ARRA - Health Information Technology - Beacon Communities The purpose of the Beacon Community Cooperative Agreement Program is to provide funding to communities to build and strengthen their health information technology (health IT) infrastructure and exchange capabilities to demonstrate the vision o... Show more
This spending item is part of a $13,775,630 allocation. See details
Health and Human Services, Department of 9/02/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $760,625 Trans-NIH Recovery Act Research Support The protozoan parasite Toxoplasma gondii causes life-threatening disease in immunocompromised individuals. While effective at controlling acute disease, available drugs fail to clear chronic, latent infection with T. gondii. An in-depth understanding of t National Institutes of Health 8/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $748,445 Trans-NIH Recovery Act Research Support Our long-term goal is an understanding of the mechanisms of eye and lens development. In this application, our more restricted goal is an understanding of how the unusual trans-membrane protein CRIM1 mediates epithelial adhesion and morphogenesis. We will National Institutes of Health 5/21/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $748,047 Trans-NIH Recovery Act Research Support Stem cell populations in the body are surrounded by G?nichesG? of specialized cells that control stem cell behavior, including the property of pluripotency. Stem cells are released from their niches in a controlled fashion to differentiate into the specia National Institutes of Health 7/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $748,047 Trans-NIH Recovery Act Research Support Stem cell populations in the body are surrounded by G?nichesG? of specialized cells that control stem cell behavior, including the property of pluripotency. Stem cells are released from their niches in a controlled fashion to differentiate into the specia National Institutes of Health 7/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $743,628 Trans-NIH Recovery Act Research Support Eosinophilic esophagitis (EE) is an emerging entity throughout the world, as documented by the recent case series from the developed countries including USA. Despite the increased incidence of EE there is limited information regarding its underlying patho National Institutes of Health 7/22/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $741,794 Trans-NIH Recovery Act Research Support Hematopoietic as well as leukemic stem cells (HSC/LSC) are dependent on interactions with extracellular matrix, soluble factors and cellular components of the bone marrow (BM) microenvironment for their survival. These interactions are hypothesized to pro National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $739,133 Trans-NIH Recovery Act Research Support This proposal is the first step in a major paradigm shift leading to global acceptance of evidence-based protocol-driven care as the optimal approach to treatment of pediatric rheumatic diseases by families, patients, and health care providers. Through th
This spending item is part of a $6,824,989 allocation. See details
National Institutes of Health 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $736,530 Trans-NIH Recovery Act Research Support To enhance participant recruitment efforts for genetics studies and other large-scale etiological research efforts, there is a need for an instrument that can be practically and efficiently employed in research studies of autism spectrum disorders (ASD). National Institutes of Health 9/30/2009
UNIVERSITY OF CINCINNATI $730,065 Trans-NIH Recovery Act Research Support Both bipolar mania and depression are characterized by mood instability and marked behavioral changes that appear to involve dysfunction of the anterior limbic network (ALN), a group of brain regions involved in emotional regulation and modulation. Functi National Institutes of Health 9/17/2009
UNIVERSITY OF CINCINNATI $719,514 Trans-NIH Recovery Act Research Support The goal of this research is to understand the mechanistic relationship between dietary lipid absorption and overall metabolism. The drug ezetimibe lowers plasma cholesterol by blocking its absorption in the intestine, apparently by disrupting the pathway National Institutes of Health 9/29/2009
UNIVERSITY OF CINCINNATI $711,483 Trans-NIH Recovery Act Research Support Systemic lupus erythematosus (SLE) is an autoimmune disease. The disease develops at a female-to-male ratio of 10:1. Although, several factors, such as gene polymorphisms, female sex hormone estrogen, and interferon-signaling, are implicated in gender bia National Institutes of Health 8/13/2009
UNIVERSITY OF CINCINNATI $706,500 Trans-NIH Recovery Act Research Support Pertussis toxin (PTX) is a complex AB5 toxin, comprised of the enzymatically active, 'A' subunit (S1), and the binding, 'B' oligomer (PTX-B), composed of five subunits S2, S3, S4, and S5, found in a 1:1:2:1 ratio. The B portions of AB toxins transport the National Institutes of Health 9/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $700,000 Trans-NIH Recovery Act Research Support Focal Segmental Glomerulosclerosis (FSGS) is a heterogeneous and devastating disease that is one of the major causes of renal failure. The long term goals of the research project are to provide a deeper understanding of this disease, to identify novel th National Institutes of Health 9/07/2009
UNIVERSITY OF CINCINNATI $698,326 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic 15-DK-106: Translating basic hematology concepts. Haploinsufficiency of ribosomal protein (rp) genes underlies the inherited marrow failure syndromes D
This spending item is part of a $997,824 allocation. See details
National Institutes of Health 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $695,927 Trans-NIH Recovery Act Research Support The overall goal of this proposal is to understand the contribution of metabolic, behavioral and diabetes-specific risk factors to the development of cardiovascular sub-clinical abnormalities in adolescents and young adults with T1D, as compared to non-di
This spending item is part of a $1,522,341 allocation. See details
National Institutes of Health 9/21/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $681,828 Trans-NIH Recovery Act Research Support 'Rapid progress in understanding the epidemiology and molecular virology of human caliciviruses (HuCVs) in the past decade has highlighted the importance of HuCVs as a cause of acute gastroenteritis. The recent finding that Noroviruses (NVs) recognize hum
This spending item is part of a $805,496 allocation. See details
National Institutes of Health 9/01/2009
CENTER FOR CLOSING THE HEALTH GAP IN GREATER CINCINNATI $625,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work WeTHRIVE! Community Wellness in Action Hamilton County, Ohio The Communities Putting Prevention to Work (CPPW) initiative will create county wide policy and environmental change to support he... Show more
This spending item is part of a $6,744,040 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $616,468 Trans-NIH Recovery Act Research Support This ARRA grant is a mechanism of competitive supplement to the parental R01 CA125658, awarded on Septermber 29, 2009. Since we have not had time to start the project within the last two days when an account number is being setup by the PIG??s institute,
This spending item is part of a $645,498 allocation. See details
National Institutes of Health 9/29/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $611,140 Trans-NIH Recovery Act Research Support Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease (GERD) and can lead to esophageal narrowing and stricture (1-4). EE is differentiated from GERD by the magnitude of mucosal eosinophilia and epithe
This spending item is part of a $930,342 allocation. See details
National Institutes of Health 9/18/2009
CHILD FOCUS, INC. $602,457 ARRA - Early Head Start This award provides for ARRA Early Head Start Expansion funded to serve 48 children. The Early Head Start program provides services to promote healthy development of low income families with children pre-birth to 3 years. Our program option is home-based Administration for Children and Families 11/23/2009
UNIVERSITY OF CINCINNATI $589,657 Trans-NIH Recovery Act Research Support Project Title: A Six-Month, RCT of Probuphine Safety and Efficacy in Opioid Addiction. We are conducting a six-month, randomized, placebo and active-controlled, multicenter clinical trial of Probuphine in patients with opioid dependence for the purpose
This spending item is part of a $7,586,848 allocation. See details
National Institutes of Health 9/30/2009
WINTON HILLS MED & HEALTH CTR $587,295 ARRA Health Center Integrated Services Development Initiative[g1] The CIP will provide renovation and repairs at the Winton Hills Inc. (WinMed) main site. At the WinMed @ CAA Bond Hill/Roselawn site, CIP funds will allow for the build out of 3,250 sq. ft. in an existing building and equipment for a ... Show more Health Resources and Services Administration 6/25/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $580,162 Trans-NIH Recovery Act Research Support The G?SystemsG? approach aims to capitalize on the dramatic advances in proteomics, genomics, and measurement technologies such as DNA arrays to generate a holistic understanding of biological organisms. Systems biology approaches can be profitably exploi
This spending item is part of a $889,218 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CINCINNATI $563,433 Trans-NIH Recovery Act Research Support The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center
This spending item is part of a $592,041 allocation. See details
National Institutes of Health 8/20/2009
CINCINNATI STATE TECHNICAL AND COMMUNITY COLLEGE $514,887 ARRA - Health Information Technology Professionals in Health Care The Midwest Community College Health Information Technology Consortium provides training in six work force roles to support electronic health records implementation across 10 Midwest states through campus-based training, distance learn... Show more
This spending item is part of a $14,897,896 allocation. See details
Health and Human Services, Department of 4/02/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $500,000 Trans-NIH Recovery Act Research Support A commitment to provide an enterprise data storage system has become an integral part of optimization of IT support and of basic and translational research. The reseearch data storage system will be integrated into shared resources of the CCRF research d National Institutes of Health 2/20/2010
UNIVERSITY OF CINCINNATI $500,000 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): This proposal requests funds to acquire an ultra-high-performance liquid chromatography mass spectrometry (UPLC-MS) system intended for the identification and structural characterization of nucleic acids, including tho National Institutes of Health 4/15/2010
UNIVERSITY OF CINCINNATI $499,238 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Intravital confocal imaging often requires multiple fluorescent markers with similar spectral properties, the ability to capture highly dynamic events, and stringent specimen environmental needs. Specialized instrument National Institutes of Health 5/13/2010
CINCINNATI HEALTH NETWORK INC, THE $495,630 ARRA Health Center Integrated Services Development Initiative[g1] This is a Capital Improvement Project for Health Care for the Homeless Program of the Cincinnati Health Network. The project includes the demolition/renovation of unused warehouse space in an old Brewery Bottling Company building into ... Show more Health Resources and Services Administration 6/25/2009
UNIVERSITY OF CINCINNATI $484,567 Recovery Act Comparative Effectiveness Research - AHRQ Bipolar is a severe and lifelong illness affecting 4.5% of the population ? about 14 million people in the U.S. It is one of the top 10 most disabling medical conditions worldwide according to the World Health Organization. Traditionally, the moo... Show more
This spending item is part of a $9,784,863 allocation. See details
Agency for Healthcare Research and Quality 9/28/2010
UNIVERSITY OF CINCINNATI $476,635 Trans-NIH Recovery Act Research Support Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estrogen recept
This spending item is part of a $1,906,255 allocation. See details
National Institutes of Health 9/24/2009
UNIVERSITY OF CINCINNATI $471,000 Trans-NIH Recovery Act Research Support Ecstasy (primarily containing MDMA) use continues to be major public health problem, especially among young adults. Animal studies suggest that ecstasy is a selective serotonin neurotoxin. However, the effects of ecstasy use on the human brain continue to National Institutes of Health 8/31/2009
UNIVERSITY OF CINCINNATI $466,390 Trans-NIH Recovery Act Research Support Previous studies in rats have provided evidence that brief, early-life exposures to bisphenol A (BPA) at environmentally relevant doses results in developmental reprogramming of the prostate gland via epigenetic modifications that enhance carcinogenic sus
This spending item is part of a $1,798,070 allocation. See details
National Institutes of Health 9/18/2009
NEIGHBORHOOD HEALTH CARE, INC. $454,351 ARRA Health Center Integrated Services Development Initiative[g1] ARRA - Increased demand for services. To provide access to uninsured and under-insured patients in the area. Health Resources and Services Administration 3/27/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $450,000 Trans-NIH Recovery Act Research Support Allergic disorders are a major public health problem affecting 50 million people in the United States alone. Epithelial cells are the first cells that encounter environmental exposures and they are responsible for intitiating the response to environmenta National Institutes of Health 8/13/2009
UNIVERSITY OF CINCINNATI $449,921 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Obesity and related disease such as diabetes remain major health threats in western societies. In order to better understand the molecular regulation of metabolic processes involved in body fat regulation, numerous gen National Institutes of Health 4/15/2010
UNIVERSITY OF CINCINNATI $438,667 Trans-NIH Recovery Act Research Support The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center
This spending item is part of a $559,637 allocation. See details
National Institutes of Health 9/24/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $435,389 Trans-NIH Recovery Act Research Support The title of this award is Primary Immune Deficiency Treatment Consortium (PIDTC). Primary immune deficiencies (PIDs) are rare, life-threatening inherited defects in the immune system. Specific goals are to characterize the long term outcomes and late ef
This spending item is part of a $2,483,108 allocation. See details
National Institutes of Health 9/11/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $418,458 Trans-NIH Recovery Act Research Support The overall purpose of this grant, RELM Peptides Alter Lung Defense, is to broadly determine immune mechanisms at respiratory mucosal surfaces to gain new insights that will facilitate vaccine development, which will protect mucosal surfaces from infectio National Institutes of Health 8/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $418,229 Trans-NIH Recovery Act Research Support Familial hemophagocytic lymphohistiocytosis (FHLH) is an autosomal recessive disease of immunoregulation. FHLH results from pathologic mutations in several genes that affect critical pathways regulating the function of NK and cytotoxic T cells (CTLs). Th National Institutes of Health 8/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $413,350 Trans-NIH Recovery Act Research Support We currently have projects that are ready to begin. These projects will study the genetic composition of children with lupus from the Rheumatology department and Eosinophilic Esophagitis from the Allergy and Immunology departments. The iScan is a cut National Institutes of Health 8/23/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $412,501 Trans-NIH Recovery Act Research Support The proposed research focuses on innovative, preclinical therapies for the variants of Gaucher disease, a rare, but not uncommon, inborn error of metabolism. The proposed studies use our unique mouse models of Gaucher disease to address the hypotheses tha National Institutes of Health 5/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $412,500 Trans-NIH Recovery Act Research Support Osteoporosis is a major public health problem affecting over 10 million adults, primarily women. A key contributor to osteoporosis prevention is optimizing accrual of peak bone mass. Adolescence is a dynamic period for bond mass development as nearly 50 National Institutes of Health 5/07/2009
GREATER CINCINNATI HEALTH COUNCIL, INC. $406,805 ARRA - Health Information Technology - Beacon Communities The purpose of the Beacon Community Cooperative Agreement Program is to provide funding to communities to build and strengthen their health information technology (health IT) infrastructure and exchange capabilities to demonstrate the vision o... Show more
This spending item is part of a $13,775,630 allocation. See details
Health and Human Services, Department of 9/02/2010
UNIVERSITY OF CINCINNATI $397,300 Trans-NIH Recovery Act Research Support Hepatocellular carcinoma (HCC) accounts for an estimated 600,000 deaths annually, and in North America mortality due to HCC has nearly doubled in the last 20 years. Recently it has been shown that the signaling pathway controlled by the mammalian Target O National Institutes of Health 8/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $386,385 Trans-NIH Recovery Act Research Support The Pediatric Rheumatology Tissue Core (PRTR) within Cincinnati P30 Rheumatic Diseases Core Center is a long standing, proven, and valuable resource for pediatric rheumatic disease translational research studies and houses approximately 80,000 samples. S National Institutes of Health 9/10/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $381,250 Trans-NIH Recovery Act Research Support The purpose of the current award is to define the importance of the Guanylate Cyclase C (GC-C) signaling system in the pathogenesis of Inflammatory Bowel Disease (IBD). Our current work indicates that in both animal models systems as well as in pediatric National Institutes of Health 7/28/2010
UNIVERSITY OF CINCINNATI $358,323 Trans-NIH Recovery Act Research Support In order for structural biologists to continue to tackle increasingly difficult problems, it is vital to exploit whatever technological advances are available. The current proposal requests funds to purchase a state-of-the-art console for the 800 MHz NMR National Institutes of Health 12/09/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $357,901 Trans-NIH Recovery Act Research Support This is significant to public health because it will determine if products of oxidative stress are biologically relevant biomarkers of diesel exhaust exposure-induced oxidative stress and asthma severity in children. Conequently, these and planned future
This spending item is part of a $402,634 allocation. See details
National Institutes of Health 5/29/2009
UNIVERSITY OF CINCINNATI $349,722 Trans-NIH Recovery Act Research Support Arteriovenous (AV) fistula non-maturation is currently a huge clinical problem and a major cause of morbidity and increased costs in the hemodialysis population. Although AV fistulae are the preferred mode of dialysis access they have a very high incidenc National Institutes of Health 9/07/2009
UNIVERSITY OF CINCINNATI $349,484 Trans-NIH Recovery Act Research Support Manganese (Mn) is an essential element, yet is neurotoxic in excess. Despite the fact that infants and young children may be at greater risk for Mn neurotoxicity than adults, very few studies have evaluated the effect of chronic Mn exposure on child devel National Institutes of Health 9/03/2009
GREATER CINCINNATI HEALTH BRIDGE, INC $343,128 In support of the Public Health Laboratory Interoperability Solutions and Solution Architecture (PHLISSA) Task Order, SAIC will support the development of standards-based architectures to continue the significant progress toward full interoperability amon
This spending item is part of a $3,672,289 allocation. See details
Centers for Disease Control and Prevention 7/09/2010
HAMILTON COUNTY EDUCATIONAL SERVICE CENTER $335,547 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and pay for hig
This spending item is part of a $1,829,607 allocation. See details
Administration for Children and Families 6/25/2009
UNIVERSITY OF CINCINNATI $318,180 Trans-NIH Recovery Act Research Support Goals: The parent award addresses the epigenetic basis whereby developmental exposures to natural or environmental estrogens predispose to prostate carcinoma with aging. Our working hypothesis is that natural or environmental estrogenic exposures at envi
This spending item is part of a $561,382 allocation. See details
National Institutes of Health 9/04/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $315,359 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-HL-109: Generate Reagents for Studying Lung Cell Biology and Disease Progression. The application focuses on the compelling need to generate cell-s
This spending item is part of a $1,000,000 allocation. See details
National Institutes of Health 9/18/2009
HEALTHCARE CONNECTION, INC.,THE $310,315 ARRA Health Center Integrated Services Development Initiative[g1] Funds made available by the Recovery Act will support health centers in their efforts to address the increased demand for services nationwide as well as create employment opportunities in underserved communities over the next two years... Show more Health Resources and Services Administration 3/27/2009
UNIVERSITY OF CINCINNATI $309,056 Trans-NIH Recovery Act Research Support The G?SystemsG? approach aims to capitalize on the dramatic advances in proteomics, genomics, and measurement technologies such as DNA arrays to generate a holistic understanding of biological organisms. Systems biology approaches can be profitably exploi
This spending item is part of a $889,218 allocation. See details
National Institutes of Health 9/25/2009
UNIVERSITY OF CINCINNATI $303,500 Technical support and administrative/management services: Task Order 6, Antiviral and Immune Plasma Infrastructure Development
This spending item is part of a $12,962,657 allocation. See details
National Institutes of Health 9/28/2009
Council On Aging of Southwestern Ohio $302,944 Aging Congregate Nutrition Services for States The Adminstration of Aging has made additional funding available for congregate meals. These funds support community programs that provide nutritious meals to individuals age 60 andolder at congregate settings (e.g., senior centers, churches).
This spending item is part of a $2,502,601 allocation. See details
Administration on Aging 3/18/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $297,846 Trans-NIH Recovery Act Research Support This project addresses the efficient operation of the Teen-LABS Data Coordinating Center (DCC) which is essential. In the spring of 2009, at the request of the NIDDK, Dr. Steven Belle and colleagues from The Epidemiology Data Center at the University Of P National Institutes of Health 6/14/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $294,200 Trans-NIH Recovery Act Research Support PURPOSE and OUTCOME: 1) To expand the Pilot/Feasibility (P/F) Program - We have transferred $20,000 to each of the three 2009 P/F awardees. We will also use funds to issue new P/F awards of $40-50,000 depending on budgetary needs of individual applicatio National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $294,103 Trans-NIH Recovery Act Research Support Purpose: The study will determine the influence of genetic risk factors on radiotherapy sensitivity among childhood cancer survivors, using the existing Childhood Cancer Survivor Study (CCSS) cohort. The Childhood Cancer Survivor Study (CCSS) is a retros
This spending item is part of a $410,944 allocation. See details
National Institutes of Health 7/16/2009
UNIVERSITY OF CINCINNATI $293,500 Trans-NIH Recovery Act Research Support The dimorphic fungus, Histoplasma capsulatum (Hc) is endemic to the Midwestern and southeastern United States. Most infections are mild or asymptomatic. The organism establishes a latent state and can cause a life-threatening infection in immunocompetent National Institutes of Health 9/01/2009
UNIVERSITY OF CINCINNATI $285,618 Trans-NIH Recovery Act Research Support Here we investigate a novel antimicrobial approach using the metal gallium (Ga) as a 'Trojan horse' to disrupt bacterial Fe metabolism. Ga has a nearly identical ionic radius as Fe, and many biologic systems are unable to distinguish Ga from Fe. Ga disr
This spending item is part of a $907,417 allocation. See details
National Institutes of Health 5/30/2009
XAVIER UNIVERSITY $283,781 ARRA ? Equipment to Enhance Training for Health Professionals The ARRA-Equipment to Enhance Training for Health Professionals grant was awarded to Xavier University to purchase equipment for the simulation lab on campus. Health Resources and Services Administration 9/05/2010
UNIVERSITY OF CINCINNATI $279,327 Trans-NIH Recovery Act Research Support Obesity is a worldwide health epidemic and a major contributor to the increased prevalence and severity of more than 60 metabolic, inflammatory, degenerative, cognitive, and neoplastic disorders. Broadly effective preventive and therapeutic strategies hav
This spending item is part of a $3,811,268 allocation. See details
National Institutes of Health 9/30/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $278,684 Trans-NIH Recovery Act Research Support The highly polymorphic HLA class I and II genes play an essential role in immune recognition, and underlie susceptibility to autoimmune diseases [1]. In particular, multiple associations between HLA alleles and rheumatoic diseases, including rheumatoid ar
This spending item is part of a $305,079 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF CINCINNATI $274,562 Trans-NIH Recovery Act Research Support This administrative supplement is associated with the parent grant G?Collectins and Innate Defense against Inhaled Pathogens, Grant # 1-PO1-AI083222-01A2 (B. Seaton, PI). We will use this supplementary funding to extend the parent grantG??s studies on co
This spending item is part of a $945,582 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CINCINNATI $269,511 ARRA ? Equipment to Enhance Training for Health Professionals The equipment to be purchased will facilitate the training of individuals across a broad spectrum of Allied Health professions, including college students, current practitioners and high school students interested in pursuing a health care... Show more Health Resources and Services Administration 9/05/2010
UNIVERSITY OF CINCINNATI $267,314 Trans-NIH Recovery Act Research Support Heart disease is a leading cause of death worldwide. Increasing evidence indicates that apoptosis, associated with detrimental structural and functional alterations, is a major contributor in the progression of cardiac remodeling and heart failure. Thus, National Institutes of Health 7/13/2009
UNIVERSITY OF CINCINNATI $262,190 Trans-NIH Recovery Act Research Support he central theme of the Program Project is to understand the innate host defense mechanisms against inhaled pathogens by the two pulmonary collectins, surfactant proteins A and D (SP-A, SP-D). This understanding is important not only in the context of pre
This spending item is part of a $3,974,096 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF CINCINNATI $262,190 Trans-NIH Recovery Act Research Support he central theme of the Program Project is to understand the innate host defense mechanisms against inhaled pathogens by the two pulmonary collectins, surfactant proteins A and D (SP-A, SP-D). This understanding is important not only in the context of pre
This spending item is part of a $3,974,096 allocation. See details
National Institutes of Health 9/01/2009
CINCINNATI HEALTH NETWORK INC, THE $260,281 ARRA Health Center Integrated Services Development Initiative[g1] This Increased Demand for Services grant includes funding for additional positions within the Health Care for the Homeless Program. Grant funds will be used to add a 1.0 FTE ANP/RN and a 1.0 FTE Licensed Clinical Counselor. A 1.0 FTE D... Show more Health Resources and Services Administration 3/27/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $257,768 Trans-NIH Recovery Act Research Support Our current research, supported by R01 DC008651, focuses on determining the pharmacokinetics, safety and efficacy of intratympanic antiviral drug delivery as a method for treating Cytomegalovirus (CMV)-related inner ear disease and hearing loss. The ratio National Institutes of Health 7/17/2009
CINCINNATI UNION BETHEL $256,835 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and pay for hig
This spending item is part of a $1,829,607 allocation. See details
Administration for Children and Families 6/25/2009
CINCINNATI CITY SCHOOL DISTRICT $252,472 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and pay for hig
This spending item is part of a $1,829,607 allocation. See details
Administration for Children and Families 6/25/2009
UNIVERSITY OF CINCINNATI $251,904 Trans-NIH Recovery Act Research Support The objective is to renew and increase MSTP funding for the University of Cincinnati College of Medicine (UCCOM) Physician Scientist Training Program (PSTP) which contributes well-trained physician-scientists to the national biomedical research, teaching National Institutes of Health 9/09/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $249,678 Trans-NIH Recovery Act Research Support The Children's Hospital of Philadelphia (CHOP) contributes substantially to the local economy. In 2008, CHOP's operations created and supported over 16,882 jobs in the region, and CHOP's total economic impact was over $5.9 billion. Moreover, through a com
This spending item is part of a $958,961 allocation. See details
National Institutes of Health 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $249,023 Trans-NIH Recovery Act Research Support The overall purpose of this supplement is to create a new position in our laboratory for a postdoctoral research fellow, thus accelerating the tempo of our research and promoting new job creation. Research supported by HL-091769 is defining important new National Institutes of Health 7/30/2009
UNIVERSITY OF CINCINNATI $246,973 Trans-NIH Recovery Act Research Support Transplantation of tissue-engineered skin grafts has delivered new medical benefits to patients with acute skin wounds arising from extensive, full-thickness burns, but applications of these devices to elective surgery (i.e., burn scars) is compromised by National Institutes of Health 9/25/2009
CHILD FOCUS, INC. $246,835 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. ARRA COLA and Quality Funds will be used to increase compensation of all Head Start and Early Head Start sta Administration for Children and Families 6/24/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $244,686 Trans-NIH Recovery Act Research Support The purpose of this contract is to hire a post-doctoral researcher to assist in the completion of research studies focused on the role of signaling pathwasy mediating pulmonary fibrosis. Expected outcomes from this contract will include providing empoymen National Institutes of Health 7/16/2009
UNIVERSITY OF CINCINNATI $243,994 Trans-NIH Recovery Act Research Support This proposal, from a group of established scientists at the University of Cincinnati is in response to RFA DK-00-014 to continue funding for one of five NIH-funded Mouse Metabolic Phenotyping Centers with the mission of providing phenotyping services rel National Institutes of Health 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $242,753 Trans-NIH Recovery Act Research Support 1A. Bioinformatically define targets of miR-21 and miR-196b, then identify those that are expressed in myeloid progenitors. 1B. Define the sensitivity of these targets to miR-21 and miR-196b knockdown through a luciferase-sensor assay (luciferase tagge National Institutes of Health 7/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $242,069 Trans-NIH Recovery Act Research Support Overall Purpose - Fanconi anemia (FA) is a recessive genetic instability syndrome that has uncovered a cellular pathway involved in the protection against replication-blocking lesions. Inactivation of this pathway, as seen in FA patients, results in National Institutes of Health 7/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $241,255 Trans-NIH Recovery Act Research Support This application entitled 'Development of a Brief Screener for Research in Autism Spectrum Disorders' addresses broad challenge area (04) Clinical Research, 04-MH-101* Autism: Addressing the challenge. The proposal aims to develop a research screening ins
This spending item is part of a $996,692 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF CINCINNATI $239,806 Trans-NIH Recovery Act Research Support Obesity and type 2 diabetes share several metabolic abnormalities, including an impaired ability of cells to sense increased nutrients flux. Since the brain plays a crucial role in regulating the homeostasis of fuel metabolism and body weight, the ultimat
This spending item is part of a $442,060 allocation. See details
National Institutes of Health 8/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $238,267 Trans-NIH Recovery Act Research Support This proposal seeks supplementary funding for investigations into the HLA region (MHC) of children with Juvenile Idiopathic Arthritis (JIA). The proposed work is within the scope of the initial U01 award (U01-AI067150 HLA/KIR Region Genetics in Pediatric
This spending item is part of a $271,614 allocation. See details
National Institutes of Health 6/28/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $233,084 Trans-NIH Recovery Act Research Support Supplemental Aim 1. We will elucidate the role of TopBP1 in linking Rad9 to ATR-dependent regulation of FANCD2 monoubiquitination in hematopoietic cells. G?? We will examine the requirement for TopBP1 in regulating FANCD2 monoubiquitination in CD34+ cell National Institutes of Health 8/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $225,351 Trans-NIH Recovery Act Research Support A link between tumor cell-associated procoagulant function (i.e., tissue factor expression) and tumor dissemination is well established. However, the mechanistic details are not fully defined. We have previously shown that tumor cell-associated tissue f National Institutes of Health 8/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $220,096 Trans-NIH Recovery Act Research Support This competitive revision will stringently adhere to the ARRA by retaining the position of a Research Associate and creating one position for a Research Assistant and a part-time position for an undergraduate student and stimulating the economy through th
This spending item is part of a $278,729 allocation. See details
National Institutes of Health 9/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $219,317 Trans-NIH Recovery Act Research Support The proposed line of research is directly related to our funded studies of DEK gene function entitled G?Role and regulation of the human DEK oncogene.G? DEK expression is upregulated in a wide variety of human cancers, and DEK had therefore long been susp National Institutes of Health 9/01/2009
OSMIC ENTERPRISES, INC. $219,225 Trans-NIH Recovery Act Research Support The parent grant (Cellulose-Based Strips for Human Taste Function) involves the development of edible taste strips that contain either sweet, sour, salty, or bitter taste stimuli for use in a clinical taste test. Currently, no commercially available taste National Institutes of Health 7/15/2009
WINTON HILLS MED & HEALTH CTR $216,164 ARRA Health Center Integrated Services Development Initiative[g1] Winton Hills Medical & Health Center, Inc.(WinMed, a Section 330(e) community health center grantee, providing health care services to diverse uninsured population and medically underserved communities in the Greater Cincinnati, Hamilt... Show more Health Resources and Services Administration 3/27/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $215,801 Trans-NIH Recovery Act Research Support The Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study was funded in 2006 as an ancillary to the adult Longitudinal Assessment of Bariatric Surgery (LABS) study. A primary goal of Teen-LABS is the accurate and objective assessment of ris
This spending item is part of a $305,862 allocation. See details
National Institutes of Health 6/19/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $213,217 Trans-NIH Recovery Act Research Support Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disease with deregulated expression of the fusion gene p210-BCR-ABL. Molecular targeting of p210-BCR-ABL by inhibiting the abl kinase activity with Imatinib or other agents can suppress gro National Institutes of Health 7/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $208,868 Trans-NIH Recovery Act Research Support Achieving the aims described in this application will inform the development of interventions designed to improve early breastfeeding outcomes among obese women. These efforts potentially have great public health impact given the high prevalence of obesit
This spending item is part of a $318,670 allocation. See details
National Institutes of Health 9/01/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $208,747 The present application addresses a major area of concern in the substance use field G?? the association between attention-deficit/hyperactivity disorder (ADHD) in childhood and patterns of substance use, abuse, and dependence (as well as desistance) in l
This spending item is part of a $756,423 allocation. See details
National Institutes of Health 4/22/2010
UNIVERSITY OF CINCINNATI $207,946 Trans-NIH Recovery Act Research Support Intravenous recombinant tissue plasminogen activator (IV rt-PA) is an effective therapy for acute ischemic stroke but has substantial limitations when used alone to open occluded major extracranial and intracranial arteries. The EMS and IMS I Pilot Studie
This spending item is part of a $335,100 allocation. See details
National Institutes of Health 9/07/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $199,725 ARRA Accelerating Adoption of Comparative Effectiveness Research (CER) The Agency for Healthcare Research and Quality and the Institute of Medicine have called for the adoption of improved handoff tools and processes to address the high incidence of harmful communication failures in hospitals. Compar... Show more
This spending item is part of a $2,993,464 allocation. See details
National Institutes of Health 9/21/2010
Nutrition Council $192,000 ARRA - Prevention and Wellness--Communities Putting Prevention to Work Communities Putting Prevention to Work WeTHRIVE! Community Wellness in Action Hamilton County, Ohio The Communities Putting Prevention to Work (CPPW) initiative will create county wide policy and environmental change to support he... Show more
This spending item is part of a $6,744,040 allocation. See details
Centers for Disease Control and Prevention 3/19/2010
UNIVERSITY OF CINCINNATI $186,275 Trans-NIH Recovery Act Research Support This application is a competitive revision of the parent grant R01GM064619 and is being submitted in response to notice # NOT-OD-09-058. The competitive revision seeks to develop a point-of-care platform for measuring serum zinc concentrations in children
This spending item is part of a $275,026 allocation. See details
National Institutes of Health 9/28/2009
UNIVERSITY OF CINCINNATI $185,713 Trans-NIH Recovery Act Research Support There are more persons who die from lung cancer than from breast, colon, and prostate cancer combined. The objective of the Genetic Epidemiology of Lung Cancer Consortium (GELCC) is to conduct family-based studies to identify susceptibility genes in famil
This spending item is part of a $880,446 allocation. See details
National Institutes of Health 9/17/2009
UNIVERSITY OF CINCINNATI $184,312 Trans-NIH Recovery Act Research Support The parent grant is based on mounting evidence that targeted inhibition of signaling molecules is an efficacious strategy for the treatment of a number of hu-?man cancers. In the parent proposal, our hypothesis is that efficient therapeutic strategies aga
This spending item is part of a $197,229 allocation. See details
National Institutes of Health 9/07/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $182,794 Trans-NIH Recovery Act Research Support The long-term goal of our research is to make feasible the clinical translation of experimental fetal cardiac surgery, i.e., open-heart surgery in utero, for babies affected with the most severe congenital heart defects. Despite continuing efforts, the m National Institutes of Health 7/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $171,970 Trans-NIH Recovery Act Research Support This award provides salary support for a graduate student, Mardi Sutherland. Mardi is using a conditional mouse model of Zic3 to study the tissue and developmental stage specific requirement for Zic3. In this quarter, Mardi has been testing the efficiency National Institutes of Health 7/16/2009
UNIVERSITY OF CINCINNATI $170,399 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Temporal processing properties of the auditory system in cochlear implant users Description of the Project One of the major challenges in cochlear implants (CIs) is the large variability in CI patients' speech percepti
This spending item is part of a $487,434 allocation. See details
National Institutes of Health 4/08/2010
UNIVERSITY OF CINCINNATI $156,916 Trans-NIH Recovery Act Research Support Thyroid diseases affect over 25 million Americans and constitute the second most common group of metabolic disorders. Thyroid hormone (TH) is critical for growth, development, and metabolism, and works by binding TH receptors in the cell nucleus and chang National Institutes of Health 4/29/2009
UNIVERSITY OF CINCINNATI $155,626 Trans-NIH Recovery Act Research Support Metabolic syndrome (MetS), a constellation of risk factors associated with development of cardiovascular disease and Type 2 diabetes, has reached epidemic proportions in western industrialized nations. About 47 million Americans have MetS. Consequently, i National Institutes of Health 9/14/2009
UNIVERSITY OF CINCINNATI $151,528 Trans-NIH Recovery Act Research Support The importance of somatic mutation in the genesis of cancer and other diseases is undisputed. However, the extent to which loss of heterozygosity (LOH), as a consequence of mitotic recombination, contributes to the frequency of spontaneous mutation has be National Institutes of Health 9/06/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $151,476 Trans-NIH Recovery Act Research Support The Cincinnati Children's Hospital Medical Center Pediatric Pharmacology Research Unit (CCHMC PPRU) Network site has evolved into a premier pediatric clinical pharmacology and pharmacometrics program during the previous funding cycles, with concentrated i National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $150,000 Trans-NIH Recovery Act Research Support The principal goal of this grant is to determine whether neonatal seizures disrupt the integration of hippocampal granule cells in the developing brain. This study involves exposing seven-day-old transgenic Gli1-CreERT2 X GFP reporter mice to kainic acid National Institutes of Health 6/01/2009
AKEBIA THERAPEUTICS, INC. $150,000 Trans-NIH Recovery Act Research Support Our proposal directly addresses the Program Announcement (RFA-AI-10-003) goals of ?development of broadspectrum (innate immunity) immunotherapeutic that targets NIAID Priority Agents' and establishment of ?collaborations between researchers in different d
This spending item is part of a $703,902 allocation. See details
National Institutes of Health 8/02/2010
Council On Aging of Southwestern Ohio $149,142 Aging Home-Delivered Nutrition Services for States The Administration on Aging has made additional nutritionfunds available for home-delivered meals. These funds support community programs that provide nutritious meals to individuals age 60 and older.
This spending item is part of a $1,232,050 allocation. See details
Administration on Aging 3/18/2009
UNIVERSITY OF CINCINNATI $146,553 Trans-NIH Recovery Act Research Support he central theme of the Program Project is to understand the innate host defense mechanisms against inhaled pathogens by the two pulmonary collectins, surfactant proteins A and D (SP-A, SP-D). This understanding is important not only in the context of pre
This spending item is part of a $3,974,096 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF CINCINNATI $146,553 Trans-NIH Recovery Act Research Support he central theme of the Program Project is to understand the innate host defense mechanisms against inhaled pathogens by the two pulmonary collectins, surfactant proteins A and D (SP-A, SP-D). This understanding is important not only in the context of pre
This spending item is part of a $3,974,096 allocation. See details
National Institutes of Health 9/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $146,209 Trans-NIH Recovery Act Research Support Significant health disparities exist among population subgroups. Attempts to narrow these gaps require full engagement of the populations at risk. To ensure adequate recruitment and retention of study participations that reflect the population(s) at risk,
This spending item is part of a $529,497 allocation. See details
National Institutes of Health 9/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $144,411 Trans-NIH Recovery Act Research Support In our parent proposal, we provided data to support the central hypothesis that PMLG??NB play a central role in HSV pathogenesis as a critical environmental modifier in neurons. We will test this hypothesis in the following Specific Aims: Aim 1: Determin National Institutes of Health 9/11/2009
UNIVERSITY OF CINCINNATI $141,300 Trans-NIH Recovery Act Research Support IgA nephropathy (IgAN) is the most common form of glomerulonephritis, an inflammatory disease of the kidney. IgAN is characterized by deposition of lgA1 antibodies in the glomerular mesangium of the kidney, followed by infiltration of inflammatory immune National Institutes of Health 8/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $137,250 Trans-NIH Recovery Act Research Support Dr. Rothenberg has indicated that each 2nd endoscopy (in week 12) will cost $3,000.00. This cost includes pre-op preparation, anesthesia, equipment, biopsy procurement, and pathology specimen preparation and analysis. National Institutes of Health 6/28/2010
UNIVERSITY OF CINCINNATI $137,209 Trans-NIH Recovery Act Research Support Inadequate recruitment of eligible subjects for clinical trials is a major impediment to the advancement of medicine. Use of an EHR-based, point-of-care Clinical Trial Alert (CTA) approach has been shown to significantly improve recruitment in a prior stu National Institutes of Health 9/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $131,716 Trans-NIH Recovery Act Research Support Systemic Lupus Erythematosus (SLE) is a multi-organ autoimmune disease with rising mortality that targets primarily young women and children of U.S. minorities. Although childhood-onset SLE (cSLE) has similar disease features as SLE in adults, children of National Institutes of Health 9/18/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $130,200 The purpose of this task order is to support various VRC Universal Influenza studies. Specifically,the EMMES Corporation will provide all necessary technical, clinical, and management services in order to support four phase-I clinical trials (2 adult,2 pe
This spending item is part of a $8,654,779 allocation. See details
National Institutes of Health 9/30/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $120,970 Trans-NIH Recovery Act Research Support The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center
This spending item is part of a $559,637 allocation. See details
National Institutes of Health 9/24/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $117,000 ARRA - Prevention and Wellness - Leveraging National Organizations The American Academy of Pediatrics (AAP) tobacco prevention and control ARRA Prevention and Wellness ? Leveraging National Organizations project will leverage existing AAP partners with Communities Putting Prevention the Work (CPPW) a... Show more
This spending item is part of a $1,104,597 allocation. See details
Health and Human Services, Department of 7/13/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $116,054 ARRA - Maternal and Child Health (MCH) Pediatric Research Network Program Overall Purpose: Minor blunt head trauma in children is common. Although important traumatic brain injuries are infrequent, clinicians obtain cranial computed tomography (CT) in up to 50% of children with minor blunt head trau... Show more
This spending item is part of a $3,498,012 allocation. See details
Health Resources and Services Administration 7/28/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $114,540 Trans-NIH Recovery Act Research Support The specific aims of the parental grant were to define the role of Fanconi anemia (FA) protein complexes in hematopoiesis. The ARRA supplemental fund continues the line of research proposed in Aim 3 of the parental grant, i.e. to examine whether FA protei National Institutes of Health 8/01/2009
UNIVERSITY OF CINCINNATI $113,868 Trans-NIH Recovery Act Research Support The incidence of obesity has risen dramatically over the last few decades. In addition to high caloric food intake and sedentary life style, the role of environmental factors is gaining credence. Bisphenol A (BPA) is a monomer of polycarbonate plastics us National Institutes of Health 9/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $113,292 Trans-NIH Recovery Act Research Support Drosophila embryogenesis is characterized by a highly orchestrated set of events directed by a regulatory gene cascade that creates a coordinate system along the anterior-posterior and dorsal-ventral axes of the embryo. This process must be highly canaliz
This spending item is part of a $299,747 allocation. See details
National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $112,500 Trans-NIH Recovery Act Research Support The Epilepsy Phenome/Genome Project is investigating how genes influence the phenotypes of common and rare epilepsies and has proposed to accelerate collection of phenotypic information by hiring a research assistant at each clinical center.
This spending item is part of a $1,558,189 allocation. See details
National Institutes of Health 9/25/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $112,197 Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C
This spending item is part of a $750,000 allocation. See details
National Institutes of Health 8/13/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $109,981 Trans-NIH Recovery Act Research Support In this application, we propose to enroll patients with inborn errors of bile acid metabolism into investigative protocols approved by the consortium. These inborn errors present with cholestasis in children and lead to progressive liver disease if untrea National Institutes of Health 2/02/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $108,752 Trans-NIH Recovery Act Research Support During the period of the ARR a supplement for NICHD grant number R01-HD38578 we have been able to accomplish the primary aims of the proposed work. We successfully collected MEG data from the children in the longitudinal cohort using the same language tas National Institutes of Health 7/27/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $108,724 Trans-NIH Recovery Act Research Support The main objectives of this supplemental funding is to test that FKBP52 and PRDX6 cooperatively direct an appropriate uterine environment for blastocyst implantation and pregnancy maintenance ant that FKBP52 has dual functions: first, FKBP52 optimizes PR National Institutes of Health 7/29/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $107,636 Trans-NIH Recovery Act Research Support Approximately one third of adults and up to 70% of all adolescents with severe obesity has obstructive sleep apnea (OSA). The pulmonary, cardiovascular, and cognitive consequences of this disorder are profound. Available evidence strongly supports o
This spending item is part of a $155,376 allocation. See details
National Institutes of Health 9/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $107,442 Trans-NIH Recovery Act Research Support Title: 'Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients' - This is a two-year planning grant for a future multi-center, randomized clinical trial assessing the efficacy and safety of immunosuppression withdrawal for stable pe
This spending item is part of a $888,643 allocation. See details
National Institutes of Health 9/29/2009
UNIVERSITY OF CINCINNATI $106,259 Trans-NIH Recovery Act Research Support This two-year study aims to explore the effects of prenatal and postnatal exposure to common insecticides (organophosphates and pyrethroids) by assessing neurobehavior during the newborn period and through age 4 years among an established 400-person cohor
This spending item is part of a $1,495,767 allocation. See details
National Institutes of Health 9/19/2009
UNIVERSITY OF CINCINNATI $104,270 Trans-NIH Recovery Act Research Support Dysfunction of the hypothalamo-pituitary-adrenocortical (HPA) axis is a common feature of major affective illnesses. Neuroendocrine disturbances are typically manifest as cortisol hypersecretion and glucocorticoid negative feedback resistance, both of whi National Institutes of Health 9/30/2009
UNIVERSITY OF CINCINNATI $102,341 Trans-NIH Recovery Act Research Support Posttranscriptional modifications in ribosomal ribonucleic acids (rRNAs) are difficult to identify and their function is unknown. Our knowledge of the functional role of these posttranscriptional modifications is limited largely by the lack of methods for National Institutes of Health 7/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $102,311 Trans-NIH Recovery Act Research Support This supplement is in accordance with NOT-OD-09-056 to create a job for a Research Assistant (RA) for a 1 year period. We are requesting a total of $102,311 for one year for this supplement request. This amount will cover the salary and supplies used in National Institutes of Health 6/28/2010
UNIVERSITY OF CINCINNATI $102,218 Trans-NIH Recovery Act Research Support The intestinal epithelium presents a barrier to invasion of the body by undesirable luminal contents. Using both immunohistochemistry and a new in vivo method for confocal and two-photon microscopy that allows study of living villi, we find that the intes National Institutes of Health 8/17/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $101,500 Trans-NIH Recovery Act Research Support 1. Evaluating the hypothesis that selected GCase-competitive inhibitors can act as pharmacological chaperones in vivo and can correct abnormal GCase function and glucosylceramide (GC) accumulation in visceral organs. These in vivo investigations will test National Institutes of Health 3/17/2010
UNIVERSITY OF CINCINNATI $100,915 Trans-NIH Recovery Act Research Support Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight, obesity and metabolic disease. We have established the visible burrow system (VBS) model of chronic social st National Institutes of Health 7/31/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $99,999 Trans-NIH Recovery Act Research Support Human pluriopotent/embryonic stem cells (HESCs) are a promising renewable source of material for transplantation. However genetically incompatible HESC-based approaches would require the use of aggressive immunosuppressive therapy following transplantatio National Institutes of Health 8/12/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $99,999 Trans-NIH Recovery Act Research Support In this supplement, we propose to set up a bioassay for CCK and measure CCK levels in human subjects given bile acide supplements; CCK is the hormone responsible for gallbladder contraction. There is no reliable assay for CCK that is sensitive enough to National Institutes of Health 8/31/2009
UNIVERSITY OF CINCINNATI $99,877 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): Group 1B phospholipase A2 (PLA2g1B) is synthesized by both exocrine acinar cells and endocrine B-islet cells of the pancreas. It is generally thought to act only as a lipolytic enzyme, facilitating lipid digestion and National Institutes of Health 12/30/2009
UNIVERSITY OF CINCINNATI $98,490 Trans-NIH Recovery Act Research Support This competing renewal application aims at investigating the hypothesis that exposure of human melanocytes to ultraviolet radiation (UV) and/or the physiological agonist 1-melanocyte stimulating hormone (1-MSH) or antagonist agouti signaling protein (ASIP National Institutes of Health 8/13/2009
UNIVERSITY OF CINCINNATI $97,244 Trans-NIH Recovery Act Research Support Manganese (Mn) is an essential element, yet is neurotoxic in excess. Despite the fact that infants and young children may be at greater risk for Mn neurotoxicity than adults, very few studies have evaluated the effect of chronic Mn exposure on child devel National Institutes of Health 6/17/2009
UNIVERSITY OF CINCINNATI $94,726 Trans-NIH Recovery Act Research Support Science Learning and Scientific Reasoning This application addresses broad Challenge Area (12) Science, Technology, Engineering and Mathematics Education (STEM) and specific Challenge Topic, 12-OD-101: Efficacy of educational approaches toward promoting S
This spending item is part of a $972,451 allocation. See details
National Institutes of Health 9/24/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $88,751 Trans-NIH Recovery Act Research Support This application is a competitive revision of the parent grant R01GM064619 and is being submitted in response to notice # NOT-OD-09-058. The competitive revision seeks to develop a point-of-care platform for measuring serum zinc concentrations in children
This spending item is part of a $275,026 allocation. See details
National Institutes of Health 9/28/2009
GREATER CINCINNATI OCCUPATIONAL HEALTH CENTER $88,298 Trans-NIH Recovery Act Research Support The Midwest Consortium for Hazardous Waste Worker Training will conduct HWWT and HDPTP programs. In the HWWT program, HAZWOPER training will be provided in eight states of the Midwest and on the Reservation of The Three Affiliated Tribes. We will continue
This spending item is part of a $620,494 allocation. See details
National Institutes of Health 9/06/2009
UNIVERSITY OF CINCINNATI $87,990 Trans-NIH Recovery Act Research Support This application addresses two broad Challenge Areas, (05) Comparative Effectiveness Research and (09) Health Disparities, and specific Challenge Topics, 05-MD-102 Prevention of Chronic Diseases in Disparity Populations , and 09-DA-101 Health disparities
This spending item is part of a $952,757 allocation. See details
National Institutes of Health 9/30/2009
Community Research Management Associates $87,150 The contractor shall furnish all necessary facilities, equipment, materials, and personnel, and shall perform all services necessary to conduct three clincial studies entitled FUF14 - H1N1 Adult/Ederly Clinical Study; FUF15 - H1N1 Pediatric Clinical Study
This spending item is part of a $29,360,000 allocation. See details
Office of Assistant Secretary for Administration and Management 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $85,745 Trans-NIH Recovery Act Research Support Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27
This spending item is part of a $8,081,413 allocation. See details
National Institutes of Health 9/14/2009
Council On Aging of Southwestern Ohio $84,807 ARRA - Communities Putting Prevention to Work: Chronic Disease Self-Manage In collaboration with the Recovery Act-funded Communities Putting Prevention to Work (CPPW) program, this funding will support the deployment of evidence-based chronic disease self-managment programs that empower older people ... Show more
This spending item is part of a $1,000,000 allocation. See details
Administration on Aging 3/31/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $84,323 Trans-NIH Recovery Act Research Support The overall purpose of this supplement was to accelerate the tempo of the scientific research proposed in the parent grant by testing the hypothesis that p16 has Rb independent functions mediated through p107 that are critical in suppressing lung tumorige National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $80,750 Trans-NIH Recovery Act Research Support This award provides partial salary support for a bioinformatician, Walter Jessen, PhD. Dr. Jessen will use bioinformatics to study the differential expression of genes in an EGFR-expressing progenitor-like cell population in human neurofibromas. The awa National Institutes of Health 9/21/2009
UNIVERSITY OF CINCINNATI $78,695 Trans-NIH Recovery Act Research Support Declining immune function is well described in the elderly, and contributes significantly to increased risk and severity of infection, impaired responses to vaccination, and poorer control of cancer. Infections with several pathogens, whether viral (e.g.,
This spending item is part of a $945,026 allocation. See details
National Institutes of Health 9/01/2009
UNIVERSITY OF CINCINNATI $78,500 Trans-NIH Recovery Act Research Support Abstract Despite increasing recognition that BPA has harmful effects on the reproductive, nervous and immune systems. While higher urine BPA concentrations are associated with cardiovascular disease in humans, the effect(s) of BPA at environmentally relev National Institutes of Health 7/22/2010
Urban Appalachian Council $78,000 Trans-NIH Recovery Act Research Support Significant health disparities exist among population subgroups. Attempts to narrow these gaps require full engagement of the populations at risk. To ensure adequate recruitment and retention of study participations that reflect the population(s) at risk,
This spending item is part of a $529,497 allocation. See details
National Institutes of Health 9/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $77,817 Trans-NIH Recovery Act Research Support Web-based technology is increasingly being utilized in human subject research given its cost-effectiveness, efficiency, accuracy, and convenience. Web-based technology is also an innovative approach to proactively address participant retention in longitud National Institutes of Health 1/07/2010
Community Research Management Associates $76,700 The contractor shall furnish all necessary facilities, equipment, materials, and personnel, and shall perform all services necessary to conduct three clincial studies entitled FUF14 - H1N1 Adult/Ederly Clinical Study; FUF15 - H1N1 Pediatric Clinical Study
This spending item is part of a $29,360,000 allocation. See details
Office of Assistant Secretary for Administration and Management 9/30/2009
UNIVERSITY OF CINCINNATI $73,481 Trans-NIH Recovery Act Research Support Zetia (Ezetimibe) inhibits cholesterol absorption via inhibition of NPC1-L1 mediated cholesterol transport pathway(s) in the enterocytes. We demonstrated that CD36 also plays a role in cholesterol absorption. It has also been demonstrated that the scaveng National Institutes of Health 8/14/2009
UNIVERSITY OF CINCINNATI $73,337 Trans-NIH Recovery Act Research Support The existing methods to treat posterior eye diseases are intravitreal and periocular injections or systemic drug administration. Posterior eye diseases such as posterior uveitis, endophthalmitis, and age-related macular degeneration affect more than a mil National Institutes of Health 7/01/2010
UNIVERSITY OF CINCINNATI $68,739 Trans-NIH Recovery Act Research Support The long-term overall goal of this Specialized Program of Translational Research in Acute Stroke SPOTRIAS) is to enhance and accelerate recovery of acute stroke patients by focused and innovative rapid nterventions for ischemic and hemorrhagic stroke. Thi
This spending item is part of a $111,195 allocation. See details
National Institutes of Health 8/17/2009
UNIVERSITY OF CINCINNATI $67,510 Trans-NIH Recovery Act Research Support This application proposes to continue our studies of the Na,K-ATPase and is directed toward several ongoing goals. One of these is to test whether the cardiac glycoside binding site of the alpha2 or alpha3 isoforms of this enzyme, which is highly conserve National Institutes of Health 6/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $67,025 Trans-NIH Recovery Act Research Support The Fogarty International Clinical Research Scholars & Fellows Support Center @ Vanderbilt University G?? Association of American Medical Colleges (FICRS?F) requests an administrative increase for the Fogarty International Clinical Research Scholars Suppo
This spending item is part of a $3,000,000 allocation. See details
National Institutes of Health 6/20/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $63,900 Trans-NIH Recovery Act Research Support The purpose of this Administrative Supplement application for the parent grant R01NS050536: Drug and Non-Drug Treatment of Pediatric Chronic Headache is to enhance the activity of this randomized clinical trial by increasing the rate of enrollment, increa National Institutes of Health 9/25/2009
UNIVERSITY OF CINCINNATI $62,564 ARRA - Head Start ARRA Cost of Living Adjustment (COLA) and Quality Improvement Funding consistent with the provisions of Section 640(a)(5) of the Head Start Act. CAA requested one-time ARRA dollars to temporarily increase staff salaries and fringe benefits and pay for hig
This spending item is part of a $1,829,607 allocation. See details
Administration for Children and Families 6/25/2009
UNIVERSITY OF CINCINNATI $58,633 Trans-NIH Recovery Act Research Support This competitive revision will stringently adhere to the ARRA by retaining the position of a Research Associate and creating one position for a Research Assistant and a part-time position for an undergraduate student and stimulating the economy through th
This spending item is part of a $278,729 allocation. See details
National Institutes of Health 9/17/2009
UNIVERSITY OF CINCINNATI $58,000 Trans-NIH Recovery Act Research Support This administrative supplement supports the aims of one of the four interrelated projects of the parent grant, ?The Role of Airborne PAHs and DEP in the Pathogenesis of Childhood Asthma.? Project 3, ?Prenatal PAH Exposure, Epigenetic Changes, and Asthma,
This spending item is part of a $212,191 allocation. See details
National Institutes of Health 9/17/2009
UNIVERSITY OF CINCINNATI $54,000 Trans-NIH Recovery Act Research Support The aim of this NIMH Mentored Patient-Oriented Research Career Development Award application is to support my career objective to become an independent investigator specializing in the relationship between neurobiological mechanisms and clinical features National Institutes of Health 7/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $54,000 Trans-NIH Recovery Act Research Support The purpose of the Administrative Supplement application for the parent grant 5K24 DK059492-08 is to create a position at Cincinnati Children's Hospital to meet the needs of the projects supported by the K24 parent grant. The supplement will increase the National Institutes of Health 9/07/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $49,926 Trans-NIH Recovery Act Research Support The purpose of this supplement application is to enable the hiring of new personnel to ensure the successful, timely completion of recruitment, enrollment, and follow-up, and to complete and enhance analyses of ongoing data collection using new and reallo National Institutes of Health 9/22/2009
UNIVERSITY OF CINCINNATI $49,711 Trans-NIH Recovery Act Research Support This competing renewal application aims at investigating the hypothesis that exposure of human melanocytes to ultraviolet radiation (UV) and/or the physiological agonist 1-melanocyte stimulating hormone (1-MSH) or antagonist agouti signaling protein (ASIP National Institutes of Health 6/17/2009
UNIVERSITY OF CINCINNATI $47,000 Trans-NIH Recovery Act Research Support Liver disease has emerged as a major source of morbidity and mortality in the United States with a disproportionate representation in some identifiable groups. Furthermore, unique management and treatment issues are associated with identifiable groups whi National Institutes of Health 1/20/2010
UNIVERSITY OF CINCINNATI $46,042 Trans-NIH Recovery Act Research Support A number of diseases affecting the gastrointestinal tract are characterized by the dysregulation of ion and fluid transport resulting in diarrhea or constipation. Over the past fifty years, a plethora of studies have focused on possible mechanisms and tre National Institutes of Health 8/21/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $45,999 Trans-NIH Recovery Act Research Support This supplemental award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ANBL0931, which is a Phase III Study of Chimeric Antibody 14.18 in High-Risk Neuroblastoma. The primary objective of study ANBL09
This spending item is part of a $1,981,588 allocation. See details
National Institutes of Health 8/07/2009
UNIVERSITY OF CINCINNATI $45,398 We have been awarded the 'RECOVERY-Tissue Source Site (TSS) Networks in Support of The Cancer Genome Atlas (TCGA) Program' contract to provide gliomas to the NCI. Specifically to establish a TSS network capable of delivering clinically annotated biospeci
This spending item is part of a $715,438 allocation. See details
National Institutes of Health 9/24/2010
UNIVERSITY OF CINCINNATI $44,733 Trans-NIH Recovery Act Research Support This is significant to public health because it will determine if products of oxidative stress are biologically relevant biomarkers of diesel exhaust exposure-induced oxidative stress and asthma severity in children. Conequently, these and planned future
This spending item is part of a $402,634 allocation. See details
National Institutes of Health 5/29/2009
UNIVERSITY OF CINCINNATI $35,846 Trans-NIH Recovery Act Research Support DMT1 is a widely-expressed iron transporter that is essential for adequate intestinal absorption of iron and for transport of iron in red blood cell precursors for the production of hemoglobin. Rare mutations in DMT1 cause severe microcytic anemia. Conver National Institutes of Health 7/16/2009
UNIVERSITY OF CINCINNATI $35,268 Trans-NIH Recovery Act Research Support Though the role of genes in heart disease is appreciated, there is currently little understanding of the mechanism by which the transcription factor NF-kB contributes to the antithetical processes of cardioprotection and ischemia/reperfusion (I/R) injury. National Institutes of Health 6/04/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $35,000 Trans-NIH Recovery Act Research Support Chronic kidney disease (CKD) in children is a devastating illness. The prevalence of patients aged 0 ? 19 years with ESRD has grown 32% since 1990 and the mortality rate for children with ESRD receiving dialysis therapy is between 30 and 150 times that o
This spending item is part of a $525,000 allocation. See details
National Institutes of Health 9/27/2009
UNIVERSITY OF CINCINNATI $33,230 ARRA - Scholarships for Disadvantaged Students The purpose of the Scholarships for Disadvantaged Students Program is to increase diversity in the health professions and nursing workforce by providing grants to eligible health professions and nursing schools for use in awarding scholarships to financi... Show more Health Resources and Services Administration 6/14/2010
UNIVERSITY OF CINCINNATI $33,158 Trans-NIH Recovery Act Research Support Depression is a highly prevalent in Parkinson's disease (PD) and is often said to contribute more to the lowered quality of life than the debilitating motor symptoms. Although the etiology of depression in PD is unknown, understanding the potential pathop National Institutes of Health 7/19/2009
UNIVERSITY OF CINCINNATI $31,382 Trans-NIH Recovery Act Research Support Merlin is the product of the neurofibromatosis type 2 (NF2) gene. In humans, loss of merlin is associated with the development of a variety of tumors including schwannomas, meningiomas, ependymomas and mesotheliomas. That both NF2 alleles must be inactiva National Institutes of Health 6/02/2009
UNIVERSITY OF CINCINNATI $31,184 ARRA - Scholarships for Disadvantaged Students The ARRA SDS grant will be used to provide tuition scholarships of approximately $6,200 each to five University of Cincinnati College of Medicine medical students who meet the definition of disadvantaged established by HRSA.-? The scholarship credits wil... Show more Health Resources and Services Administration 9/03/2009
UNIVERSITY OF CINCINNATI $30,386 Trans-NIH Recovery Act Research Support Purpose: The study will determine the influence of genetic risk factors on radiotherapy sensitivity among childhood cancer survivors, using the existing Childhood Cancer Survivor Study (CCSS) cohort. The Childhood Cancer Survivor Study (CCSS) is a retros
This spending item is part of a $410,944 allocation. See details
National Institutes of Health 7/16/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $30,000 Trans-NIH Recovery Act Research Support The purpose of the supplement is to encourage and motivate students into the field of medical research. Therefore, the principal investigator (PI) submitted administrative supplement in view of the NIH notice (NOT-OD-060) to obtain additional funds to re National Institutes of Health 7/13/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $29,639 Trans-NIH Recovery Act Research Support To our knowledge, no research group has conducted and analyzed direct observation of family interactions that focus on promotion of adolescent autonomy in the management of Type 1 diabetes and the relationship to treatment adherence in a prospective study National Institutes of Health 7/15/2009
UNIVERSITY OF CINCINNATI $29,030 Trans-NIH Recovery Act Research Support This ARRA grant is a mechanism of competitive supplement to the parental R01 CA125658, awarded on Septermber 29, 2009. Since we have not had time to start the project within the last two days when an account number is being setup by the PIG??s institute,
This spending item is part of a $645,498 allocation. See details
National Institutes of Health 9/29/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $28,608 Trans-NIH Recovery Act Research Support The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center
This spending item is part of a $592,041 allocation. See details
National Institutes of Health 8/20/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $27,000 Trans-NIH Recovery Act Research Support The title of this award is Primary Immune Deficiency Treatment Consortium (PIDTC). Primary immune deficiencies (PIDs) are rare, life-threatening inherited defects in the immune system. Specific goals are to characterize the long term outcomes and late ef
This spending item is part of a $2,483,108 allocation. See details
National Institutes of Health 9/11/2009
UNIVERSITY OF CINCINNATI $26,395 Trans-NIH Recovery Act Research Support The highly polymorphic HLA class I and II genes play an essential role in immune recognition, and underlie susceptibility to autoimmune diseases [1]. In particular, multiple associations between HLA alleles and rheumatoic diseases, including rheumatoid ar
This spending item is part of a $305,079 allocation. See details
National Institutes of Health 9/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $25,371 Trans-NIH Recovery Act Research Support This supplement award supports the Accelerating Clinical Trials of Novel Oncologic Path Ways (ACTNOW) program for Protocol ADVL0813, which is a Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with C
This spending item is part of a $750,000 allocation. See details
National Institutes of Health 8/13/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $25,000 The purpose of this request is for a professional services contract to provide expertise and management support of the ASPE CER portfolio and the HHS contract with the NQF for quality measure endorsement activities. Program Support Center 7/19/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $22,482 Trans-NIH Recovery Act Research Support This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic 15-DK-106: Translating basic hematology concepts. Haploinsufficiency of ribosomal protein (rp) genes underlies the inherited marrow failure syndromes D
This spending item is part of a $997,824 allocation. See details
National Institutes of Health 9/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $22,465 Trans-NIH Recovery Act Research Support This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/
This spending item is part of a $1,405,307 allocation. See details
National Institutes of Health 8/12/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $20,581 Trans-NIH Recovery Act Research Support This application is submitted in response to NOT-OD-09-056 for an Administrative Supplement to R01 HD 059140 (Morrow, PI; Schibler, co-PI), G?Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants.G? This grant was awarded in January
This spending item is part of a $59,916 allocation. See details
National Institutes of Health 9/30/2009
UNIVERSITY OF CINCINNATI $17,273 Trans-NIH Recovery Act Research Support The Midwest Consortium for Hazardous Waste Worker Training will conduct HWWT and HDPTP programs. In the HWWT program, HAZWOPER training will be provided in eight states of the Midwest and on the Reservation of The Three Affiliated Tribes. We will continue
This spending item is part of a $620,494 allocation. See details
National Institutes of Health 9/06/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $16,693 Trans-NIH Recovery Act Research Support This supplemental award provides support to Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Supplements including: 1) High Risk Acute Lymphoblastic Leukemia (HR-ALL) - Our results establish that we can use comprehensive genom
This spending item is part of a $4,023,579 allocation. See details
National Institutes of Health 9/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $15,000 Trans-NIH Recovery Act Research Support The purpose of this investigation is to determine the type and frequency of the allelic variants in nuclear modifier gene TRMU involved in phenotypic expression of deafness-associated 12S rRNA mutations in the Chinese populations. For this purpose, we wi National Institutes of Health 5/29/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $15,000 Trans-NIH Recovery Act Research Support The purpose of this contract is to hire a summer research student to assist in the performance of research stuides focused on the role of signaling pathways mediating pulmonary fibrosis. Expected outcomes from this contract include summer employment, int National Institutes of Health 6/05/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $15,000 Trans-NIH Recovery Act Research Support In response to NOT-OD-09-060 Administrative Supplements Providing Summer Research Experiences for Students and Science Educators under the Recovery Act, this study proposes a 3-month summer project for two undergraduate students, one from statistics and o National Institutes of Health 6/01/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $15,000 Trans-NIH Recovery Act Research Support The purpose of this administrative supplement application is to request salary support for a summer research experience for undergraduate students in 2009 and 2010. The funding will allow students to help to conduct research through a parent grant (R01 A National Institutes of Health 6/18/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $12,917 Trans-NIH Recovery Act Research Support The parent grant is based on mounting evidence that targeted inhibition of signaling molecules is an efficacious strategy for the treatment of a number of hu-?man cancers. In the parent proposal, our hypothesis is that efficient therapeutic strategies aga
This spending item is part of a $197,229 allocation. See details
National Institutes of Health 9/07/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $12,600 Trans-NIH Recovery Act Research Support Adminstrative Supplement Notice for Students and Science Education under the Recovery Act (NOT-OD-09-060) National Institutes of Health 5/30/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $8,816 Trans-NIH Recovery Act Research Support The purpose of this Administrative Supplement application for the parent grant R01DK054915-06A1: G?Behavioral and Nutrition Treatment to Help CF Preschoolers GrowG? is to enhance the activity of this multi-center clinical trial by increasing enrollment, i
This spending item is part of a $57,690 allocation. See details
National Institutes of Health 9/30/2010
CHILDREN'S HOSPITAL MEDICAL CENTER $7,500 Trans-NIH Recovery Act Research Support This Recovery Act supplement award supported one undergraduate student to work on part of aim 1 of the parent R21 grant for 10 weeks from May to August 2009. Recruitment of the summer student was done through the highly competitive Cincinnati ChildrenG??s National Institutes of Health 6/05/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $7,500 Trans-NIH Recovery Act Research Support The infrastructure or incorporating summer students into research labs is well established at Cincinnati Children's Hospital Medical Center (CCHMC). A centralized, ongoing program, the Summer Undergraduate Research Fellowship (SURF) program at CCHMC prov National Institutes of Health 7/15/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $7,500 Trans-NIH Recovery Act Research Support This study founded by this award provides a summer research opportunity for an undergraduate student that will engage the interest in biomedical science. The study addresses the following hypotheses: 1) Prototype competitive inhibitors, termed pharmacolog National Institutes of Health 6/08/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $6,300 Trans-NIH Recovery Act Research Support The study founded by this award is to focus on defining the therapeutic effect of isofagomine (IFG), a pharmacological chap-?erone, in correcting substrate accumulation and improving the phenotype of neuronopathic variants of Gaucher disease. These resear National Institutes of Health 7/09/2009
UNIVERSITY OF CINCINNATI $5,400 Trans-NIH Recovery Act Research Support DESCRIPTION (provided by applicant): The overriding goal of this Phase II project is to promote national dissemination of the Phase I HealthRICH products and resources, as these materials effectively encourage young teens and their families to make inform
This spending item is part of a $200,000 allocation. See details
National Institutes of Health 9/09/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $3,134 Trans-NIH Recovery Act Research Support This supplemental project grant supports a new collaboration between the PI's lab and the lab of Dr. Michael Lovett at Washington University to identify the mutant gene responsible for the cleft lip and cleft palate phneotype in the Twirler mutant mice. B
This spending item is part of a $30,298 allocation. See details
National Institutes of Health 7/25/2011
SO-LOW ENVIRONMENTAL EQUIPMENT CO (INC) $2,894 LABORATORY EQUIPMENT AND SUPPLIES National Institutes of Health 4/05/2010
ROXBOROUGH MEMORIAL HOSPITAL $2,500 ARRA - Preventing Healthcare-Associated Infections This program is intended to address the Health and Human Services Action Plan to prevent healthcare associated infections (HAI). Funding will provide for technical assistance to make critical short-term investments that will provide for a sustainabl... Show more
This spending item is part of a $1,020,480 allocation. See details
Centers for Disease Control and Prevention 8/28/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $0 Trans-NIH Recovery Act Research Support This Diversity Supplement will concentrate on the genetic association with systemic lupus erythematosus (SLE) at 5q33.3 which contains the fascinating gene miR-146a. This is our primary candidate gene for causation, changing risk for SLE. The miR-146a h
This spending item is part of a $153,000 allocation. See details
National Institutes of Health 1/21/2011