Recovery Tracker

How Much Stimulus Funding is Going to Your County?

Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page

Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.

Recipient Amount Type Description Federal Dept./Agency Date
REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE $631,630 Grant Trans-NIH Recovery Act Research Support: We will accelerate the goals of the parent grant while retaining 3 existing staff and hiring 2 new staff. This application allows the Berkeley GDAC to match the productive power of the rest of the TCGA project which has been massively accelerated with ARR Health and Human Services, Department of / National Institutes of Health 9/23/2010
EMORY UNIVERSITY $426,250 Grant Trans-NIH Recovery Act Research Support: The Role of JAM-A in Regulation of Intestinal Antigen Presenting Cells and Inflammation Numerous observations have suggested that inflammatory bowel disease is a multifactorial process encompassing at least three major interacting elements: environmental Health and Human Services, Department of / National Institutes of Health 9/01/2009
UNIVERSITY OF SOUTHERN CALIFORNIA $899,999 Grant Trans-NIH Recovery Act Research Support: In the past two decades, it has become clear that cancer arises not only as a consequence of genetic events, such as mutations, copy number alterations, and sequence rearrangements, but also as a result of extensive changes to the epigenome. Epigenetic al Health and Human Services, Department of / National Institutes of Health 9/17/2010
RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA $785,839 Grant Trans-NIH Recovery Act Research Support: Project Narrative Case Western Reserve University with its collaborators at University of Louisville, and University of Minnesota with strong multidisciplinary faculty are conducting studies focused on testing the concept that infusion of C3a primed umbil Health and Human Services, Department of / National Institutes of Health 2/09/2011
MEDICAL UNIVERSITY OF SOUTH CAROLINA $99,675 Grant Trans-NIH Recovery Act Research Support: Periodontal disease initiation and progression occurs as a consequence of the host immune inflammatory response to oral pathogens. The purpose of this award is to 1)determine the role of over-expressed MKP-1 on IL-6 and TNFalpha mRNA in vitro, 2)determin Health and Human Services, Department of / National Institutes of Health 9/22/2009
UNIVERSITY OF PITTSBURGH THE $108,500 Grant Trans-NIH Recovery Act Research Support: The purpose of the administrative supplement is to request funds to purchase a Real time Taqman instrument which will be used in studies related to the parent grant. Currently, our laboratory does not have a real time PCR machine and we are using ABI 7000 Health and Human Services, Department of / National Institutes of Health 7/29/2010
WAYSIDE TECHNOLOGY GROUP, INC. $18,916 Contract : ADP Software Health and Human Services, Department of / National Institutes of Health 9/15/2010
SWARTHMORE COLLEGE $311,058 Grant Trans-NIH Recovery Act Research Support: A new analysis of errors in the perceptual evaluation of spatial orientation suggests that these may be due to cognitive biases around categorical frames of reference. Spatial orientation is a fundamental component of a broad range of spatial cognitive be Health and Human Services, Department of / National Institutes of Health 9/30/2010
WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY $205,163 Contract : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula Health and Human Services, Department of / National Institutes of Health 7/28/2010
SISKIYOU CORPORATION $5,605 Contract : Purchase order for standard products used in biological research Health and Human Services, Department of / National Institutes of Health 9/23/2010
UNIVERSITY OF PITTSBURGH THE $405,889 Grant Trans-NIH Recovery Act Research Support: Confocal microscopy using spinning disk or moving pinhole array microscopes has facilitated the adoption of optical sectioning methods as a primary tool for imaging living cells. This award will place an automated high speed widefield/confocal instrument Health and Human Services, Department of / National Institutes of Health 7/01/2010
SAN DIEGO STATE UNIVERSITY FOUNDATION $45,162 Grant Trans-NIH Recovery Act Research Support: A summer supplement for university students is requested under the American Recovery and Reinvestment Act. This will provide scientific instruction and temporary employment for four talented individuals. They will be trained in protein biochemistry, cryst Health and Human Services, Department of / National Institutes of Health 5/19/2010
VWR INTERNATIONAL, LLC $1,572 Contract : Confirmation #45647621 Health and Human Services, Department of / National Institutes of Health 10/25/2010
UNIVERSITY OF NEBRASKA $509,211 Grant Trans-NIH Recovery Act Research Support: The proposal plans to perform a comprehensive detection of fusion transcripts in acute myeloid leukemia, with the aims to identify new genes contributing to this disease and to identify new markers for clinical diagnosis, treatment and prognosis of this d Health and Human Services, Department of / National Institutes of Health 3/04/2011
JOSLIN DIABETES CENTER, INC. $399,109 Grant Trans-NIH Recovery Act Research Support: Mechanism-Based Biomarkers for Glucose-Lowering in TINSAL T2D - Background. TINSAL-T2D is a multicenter, randomized, placebo-controlled, dose-ranging clinical trial designed to determine glycemic efficacy, safety and tolerability of salsalate in patients Health and Human Services, Department of / National Institutes of Health 9/30/2010
UNITED MEDICAL LLC $52,325 Contract : Deliver and install a Fuji XC-2 CR System with Flash Lite IIP Workstation, mini PACS system, High Frequency (HF) X-Ray System with Table and attached/integrated Tubestand to create an independent imaging system, imaging storage system, and diagnostic work Health and Human Services, Department of / National Institutes of Health 9/20/2010
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO $49,139 Grant Trans-NIH Recovery Act Research Support: The title of this award is Regulatory T cell influence on infant and adult immune responses to HIV. This project will accelerate and augment the studies proposed in Aim 3 of the parent grant application. We will initiate an immediate analysis of T-reg p Health and Human Services, Department of / National Institutes of Health 9/11/2009
DANA-FARBER CANCER INSTITUTE, INC. $1,500,000 Grant Trans-NIH Recovery Act Research Support: Current vaccination strategies against influenza A viruses are primarily based upon elicitation of neutralizing antibodies directed at virion surface expressed hemagglutinin (HA) and neuraminidase (NA) proteins. Given antigenic drifts during seasonal infl Health and Human Services, Department of / National Institutes of Health 7/12/2010
NATIONAL CHILDHOOD CANCER FOUNDATION $976,412 Grant Trans-NIH Recovery Act Research Support: This award supports the Expansion of the original Acute Myeloid Leukemia (AML)Therapeutically Applicable Research to Generate Effective Treatmens (TARGET) cohort to include 50 relapse specimens as well as matching diagnostic/remission specimens from 30 pa Health and Human Services, Department of / National Institutes of Health 9/22/2010
CDW GOVERNMENT LLC $455,169 Contract : Award was for the purchase of information technology commercial items to improve agency operations or to fulfill agency requirements. Health and Human Services, Department of / National Institutes of Health 8/24/2010
UNIVERSITY OF PITTSBURGH THE $151,500 Grant Trans-NIH Recovery Act Research Support: Our grant exploring the etiology and epidemiology of type 1 diabetes, first funded in November 1978, has resulted in the collection and accumulation of serum samples and frozen white cells over 30 years. This sample collection and efficient access to it, Health and Human Services, Department of / National Institutes of Health 4/28/2010
APPLIED BIOSYSTEMS, LLC $240,000 Contract : MED & SURGICAL INSTRUMENTS,EQ & SUP Health and Human Services, Department of / National Institutes of Health 9/17/2010
S. A. C. N. A. S. $159,257 Contract : With the generous support of NIGMS over the past two decades SACNAS has already maximized services and programs for underrepresented minorities beyond the annual conference, and more recently to incorporate year round initiatives such as the SACNAS Leader Health and Human Services, Department of / National Institutes of Health 9/30/2009
3-C INSTITUTE FOR SOCIAL DEVELOPMENT, INC. $240,698 Grant Trans-NIH Recovery Act Research Support: This supplement grant builds on the WDT-C Phase I project by creating a WDT treatment outcomes module and conducting an additional feasibility test. The supplemental research is expected to demonstrate strong support for the treatment outcomes module acro Health and Human Services, Department of / National Institutes of Health 9/01/2010
LOUISIANA STATE UNIVERSITY SYSTEM $299,999 Grant Trans-NIH Recovery Act Research Support: 1) Hire a molecular biologist research associate (RA) to produce targeting contracts and screening ES cells. The duties of this person will include retrieval of targeting vector from BAC genomic DNA, insertion of lox P sites and fRT-flanked PGK-neo elect Health and Human Services, Department of / National Institutes of Health 7/20/2009
REGENTS OF THE UNIVERSITY OF MICHIGAN $184,078 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Hsp70 (heat shock 70 kDa) chaperone proteins are central to protein folding, refolding, and trafficking in organisms ranging from Archae to Homo Sapiens, both at normal and at stressed cellular conditions. Hsp70's (re) Health and Human Services, Department of / National Institutes of Health 5/26/2010
BIO-RAD LABORATORIES, INC. $47,748 Contract : Drugs & Biologicals Health and Human Services, Department of / National Institutes of Health 8/24/2010
MW DESIGN $2,000,000 Contract : A/E CA Services, Interior design services, Detailed furniture specificaitons, test fits, move coordination, shop drawing review, schedule review and on site observations Health and Human Services, Department of / National Institutes of Health 9/25/2010
GYRUS ACMI, L.P. $30,200 Contract : Flexible Uretero-Reno scopes and Cysto-Nephro Videoscope. Health and Human Services, Department of / National Institutes of Health 7/19/2009
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $847,291 Grant Trans-NIH Recovery Act Research Support: The long-term objective of this research is a detailed understanding of herpesvirus DNA polymerases and drugs that target them. These enzymes, which include a catalytic subunit (Pol) and an accessory subunit that stimulates long-chain DNA synthesis, are Health and Human Services, Department of / National Institutes of Health 5/14/2009
PIASEK BIOTECH INC $197,430 Grant Trans-NIH Recovery Act Research Support: Sleep apnea is a disorder that affects millions of Americans in which a person stops breathing during sleep for 10 seconds or longer. These episodes are known as apneas. People who have a severe form of sleep apnea can have hundreds of such episodes per h Health and Human Services, Department of / National Institutes of Health 5/05/2010
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO $50,000 Grant Trans-NIH Recovery Act Research Support: The title of this award is Oral Wash for Nucleic Acid Diagnosis and Prognosis of TB (Tuberculosis). This research project will help accelerate the pace of scientific discovery for a patient-oriented clinical research program on novel diagnostics for HIV Health and Human Services, Department of / National Institutes of Health 9/11/2009
SANARIA INC. $992,988 Grant Trans-NIH Recovery Act Research Support: Attenuated Sporozoite Malaria Vaccine Health and Human Services, Department of / National Institutes of Health 6/29/2010
EMORY UNIVERSITY $172,186 Grant Trans-NIH Recovery Act Research Support: Tuberculosis (TB) is an enormous global public health problem including in the independent country of Georgia, a former Soviet republic, which has high rates of TB including drug-resistant TB (MDR- and XDR-TB). This ARRA award is a supplement (U.S. Globa Health and Human Services, Department of / National Institutes of Health 9/03/2009
UNIVERSITY OF CALIFORNIA, LOS ANGELES $172,523 Grant Trans-NIH Recovery Act Research Support: A photobiological and functional genomics study to elucidate the functional interactions of different photoreceptor signaling pathways. How organisms respond to light and how photosensory receptors mediate light responses are some of the most basic questi Health and Human Services, Department of / National Institutes of Health 9/30/2009
UNIVERSITY OF CALIFORNIA, LOS ANGELES $1,109,758 Grant Trans-NIH Recovery Act Research Support: This project addresses the design of cellular and animal screening procedures that can be used to assess the potential danger of engineered nanomaterials that are currently being introduced into the marketplace. We will develop a predictive toxicological Health and Human Services, Department of / National Institutes of Health 9/30/2009
SEATTLE CHILDREN'S HOSPITAL $2,355,329 Grant Trans-NIH Recovery Act Research Support: Nonviral Gene Medicine for Hemophilia A -- The goal of this study is to develop a safe, efficient, and clinically feasible nonviral gene therapy strategy for the treatment of hemophilia A. Currently hemophilia A patients are treated with repeated infusio Health and Human Services, Department of / National Institutes of Health 7/17/2009
SUTTER WEST BAY HOSPITALS $675,000 Grant Trans-NIH Recovery Act Research Support: Methamphetamine addiction remains a significant public health problem with no known effective pharmacotherapies. ARRA provided funding for a research project entitled ?Sustained Release Naltrexone for Methamphetamine Dependence: Role of the A118G SNP?. Th Health and Human Services, Department of / National Institutes of Health 7/16/2009
THE CHILDRENS HOSPITAL LOS ANGELES $32,463 Grant Trans-NIH Recovery Act Research Support: Inflammatory bowel diseases are associated with increased risk of early-onset colorectal cancer, incurring great cost both economically and in patient morbidity and mortality. Intensive research has been focused on identifying signaling pathways which may Health and Human Services, Department of / National Institutes of Health 11/26/2010
UNIVERSITY OF SOUTHERN CALIFORNIA $172,692 Grant Trans-NIH Recovery Act Research Support: High blood pressure affects 50 million individuals in the United States and is a major risk factor for cardiovascular and chronic kidney disease. The body regulates blood pressure by adjusting how much salt is excreted by the kidney. The goal of this pro Health and Human Services, Department of / National Institutes of Health 8/01/2010
UNIVERSITY OF SOUTHERN CALIFORNIA $166,567 Grant Trans-NIH Recovery Act Research Support: We are requesting the Change of Grantee Institute Change of the Recovery Administrative Supplement for R01GM067735. The supplement was awarded funds for two years, which we have established to hire a college graduate into an entry level research technic Health and Human Services, Department of / National Institutes of Health 7/01/2010
UNIVERSITY OF IOWA, THE $225,000 Contract : Refactoring the ITK FEM Framework Health and Human Services, Department of / National Institutes of Health 6/21/2010
UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. $370,966 Grant Trans-NIH Recovery Act Research Support: Radioresistance markedly impairs the efficacy of radiotherapy and involves cell signal transduction pathways that prevent radiation-induced cell death. Proteins in the Bcl-2 family are central and dual regulators of apoptosis and autophagy, and members th Health and Human Services, Department of / National Institutes of Health 1/07/2011
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. $102,208 Grant Trans-NIH Recovery Act Research Support: This grant provides postdoctoral level funding for studies on the mechanism innate immunity to African trypanosomes. Humans exhibit an innate immunity to the mammalian parasite Trypanosoma brucei brucei. Immunity to T. b. brucei is provided by a subclass Health and Human Services, Department of / National Institutes of Health 7/23/2009
LELAND STANFORD JUNIOR UNIVERSITY, THE $65,388 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION: Hypospadias, a congenital malformation in which the urethral opening is on the ventral side of the penis, is one of the most common congenital malformations. The main mechanisms believed to underlie hypospadias are environmental and genetic f Health and Human Services, Department of / National Institutes of Health 3/03/2011
MEDICAL UNIVERSITY OF SOUTH CAROLINA $371,002 Grant Trans-NIH Recovery Act Research Support: Examine brain activation patterns in individuals at risk for drug abuse who are processing anti-drug media messages Health and Human Services, Department of / National Institutes of Health 3/21/2011
CHILDREN'S HOSPITAL MEDICAL CENTER $153,000 Grant Trans-NIH Recovery Act Research Support: This Diversity Supplement will concentrate on the genetic association with systemic lupus erythematosus (SLE) at 5q33.3 which contains the fascinating gene miR-146a. This is our primary candidate gene for causation, changing risk for SLE. The miR-146a h Health and Human Services, Department of / National Institutes of Health 1/21/2011
COLORADO STATE UNIVERSITY $652,948 Grant Trans-NIH Recovery Act Research Support: The primary focus of this application is to study the total synthesis and biosynthesis of complex, biomedically significant natural products constituted of tetrahydroisoquinolines. The synthetic chemistry that will be developed shall be utilized to prepar Health and Human Services, Department of / National Institutes of Health 5/07/2009
CHILDRENS HOSPITAL OF PHILADELPHIA $359,939 Grant Trans-NIH Recovery Act Research Support: This application addresses the Challenge Area (15) 'Translational Science' and the Challenge Topic 15- OD(ORDR)-101 'Pilot Projects for Prevention, Early Detection and Treatment of Rare Diseases'. Hereditary Multiple Exostosis Syndrome (HME) is a rare au Health and Human Services, Department of / National Institutes of Health 3/26/2011
DUKE UNIVERSITY $329,000 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The survival of every species depends on the faithful inheritance of genetic information. Essential to this process are the accurate movement and positioning of chromosomes and plasmids to daughter cells at cell divis Health and Human Services, Department of / National Institutes of Health 3/17/2011
BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS $1,240,552 Grant Trans-NIH Recovery Act Research Support: Poor adherence with prescription medications is ubiquitous and costly. Physicians' assessments of patients' adherence are inaccurate, which makes it attractive to use pharmacy claims to identify nonadherence. But research clearly shows that simply giving Health and Human Services, Department of / National Institutes of Health 3/24/2011
TRUSTEES OF TUFTS COLLEGE INC $439,136 Grant Trans-NIH Recovery Act Research Support: It is well recognized that the 'spectrin-actin junctions' are functionally essential for the maintenance of erythrocyte membrane stability and mechanical properties. The prevailing paradigm is that these junctions are linked to the plasma membrane via an Health and Human Services, Department of / National Institutes of Health 1/14/2011
UNIVERSITY OF NORTH CAROLINA AT GREENSBORO $129,563 Grant Trans-NIH Recovery Act Research Support: This award atms at under standing the pothogenesis of alcohol-induced gut leakiness in alcoholic liver disease (ALD) and the role of zinc. ALD is an important health problem, but an FDA-approved effective therapy is not available. Gut-derived endotoxin h Health and Human Services, Department of / National Institutes of Health 11/19/2010
UNIVERSITY OF KENTUCKY $362,141 Grant Trans-NIH Recovery Act Research Support: During the past decade, it has become evident that in vitro enzyme data obtained in solution frequently fail to provide an accurate profile of in vivo enzyme kinetic parameters. This may be due to oligomer formation. Efforts to separate the effect of olig Health and Human Services, Department of / National Institutes of Health 6/22/2011
MOUNT SINAI SCHOOL OF MEDICINE $73,024 Grant Trans-NIH Recovery Act Research Support: Award Description. Anchorage-independent survival, exhibited by many tumor and oncogene-transformed cells, enables cells to adapt to altered matrix environments and may be critical for the formation of metastases at distant sites. Therefore, proteins tha Health and Human Services, Department of / National Institutes of Health 6/03/2011
WAYNE STATE UNIVERSITY (INC) $999,094 Grant Trans-NIH Recovery Act Research Support: Malignant tumors evade the immune attack by exploiting the natural regulatory mechanisms of immune tolerance. CD4+CD25+ Tregs that play a critical role in immune tolerance accumulate in the draining lymph nodes and tumor mass of patients with multiple typ Health and Human Services, Department of / National Institutes of Health 9/30/2009
WAYNE STATE UNIVERSITY (INC) $405,000 Grant Trans-NIH Recovery Act Research Support: The goal of this project is to develop a mouse model of myopia by optimizing visual conditions for induction of experimental myopia in mice and investigating the role of the genetic background in the eye's response to visual form deprivation in mice. Health and Human Services, Department of / National Institutes of Health 7/22/2009
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE $57,029 Grant Trans-NIH Recovery Act Research Support: The long-term goal is to understand how peptidyl-prolyl isomerases (PPIases) control important cellular processes such as transcription and mitosis. PPIases catalyze the cis/trans isomerization of the peptide bond that precedes the cyclic amino acid proli Health and Human Services, Department of / National Institutes of Health 3/14/2011
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL $81,876 Grant Trans-NIH Recovery Act Research Support: Self-assembling macromolecular machines such as the ribosome and spliceosome are central to fundamental cellular processes including transcription, mRNA processing, translation, and DNA replication. Creating a quantitative and predictive description of th Health and Human Services, Department of / National Institutes of Health 1/10/2011
UNIVERSITY OF SOUTHERN CALIFORNIA $292,287 Grant Trans-NIH Recovery Act Research Support: Overview: Although there is consensus that HIV accelerates hepatitis C (HCV) disease in co-infected (HIV+HCV+) patients, studies differ regarding the impact of HCV infection on HIV disease progression. This proposal seeks continued support for our grant Health and Human Services, Department of / National Institutes of Health 9/27/2010
UNIVERSITY OF MARYLAND $137,493 Grant Trans-NIH Recovery Act Research Support: Funding is being requested for additional tasks within the scope of the parent grant. Broad scientific goal of the initial proposal is an improved understanding of evolution of gene families and transcription regulation. In specific aim 1 we had proposed Health and Human Services, Department of / National Institutes of Health 1/28/2011
PROSOURCE CONSULTING, L.L.C. $780,000 Contract : Provide support services critical to supporting the mission of the DOHS, the NIH and the Department of Health and Human Services. Tasks include but not limited to the following: mechanical/industrial/safety engineering plan reviews, mechanical/industria Health and Human Services, Department of / National Institutes of Health 9/23/2009
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. $402,808 Grant Trans-NIH Recovery Act Research Support: Endocytosis and cell signaling are important for viability of eukaryotes. In Trypanosoma brucei, little is known about cell signaling because the major receptors studied in model eukaryotes are unrecognizable in the parasite genome. T. brucei has a glycos Health and Human Services, Department of / National Institutes of Health 5/21/2009
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH $152,000 Grant Trans-NIH Recovery Act Research Support: The administrative supplement would extend this work by supporting a new analysis, based directly on patient-reported outcomes. This larger analysis would have three goals: (1) to improve the previous models, (2) to potentially validate our previous mod Health and Human Services, Department of / National Institutes of Health 1/28/2011
GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. $80,178 Grant Trans-NIH Recovery Act Research Support: Polycystic ovary syndrome (PCOS) affects approximately 7% of reproductive-aged women, and is one of the most common causes of oligo-ovulatory infertility. Insulin resistance occurs in about 70% of women with PCOS, and contributes to much of the hyperandro Health and Human Services, Department of / National Institutes of Health 1/27/2011
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON $47,925 Grant Trans-NIH Recovery Act Research Support: This is funding building on a recently completed longitudinal study of smoking patterns in a popluation-based sample of Mexican origin adolescents (the MATCH study). This funding will further explore the genetic/non-genetic underpinnings of smoking and e Health and Human Services, Department of / National Institutes of Health 3/31/2011
CHILDREN'S MERCY HOSPITAL, THE $176,253 Grant Trans-NIH Recovery Act Research Support: The goal of this project is to define the physiologic and molecular significance of the identified PBEF polymorphisims. We will determine the pathophysiological role of PBEF in inflammatory lung injury with a specific focus on a role of PBEF in increase Health and Human Services, Department of / National Institutes of Health 2/10/2011
NATIONAL JEWISH HEALTH $771,842 Grant Trans-NIH Recovery Act Research Support: The importance of T cells in the pathogenesis of asthma and other allergic diseases is undisputed. The extend of the T cell respose is tightly controlled by a variety of homeostatic mechanisms. T regulatory cells (Tregs) represent a major homeostatic me Health and Human Services, Department of / National Institutes of Health 5/21/2009
RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA $114,990 Grant Trans-NIH Recovery Act Research Support: To define the mechanism by which early inflammatory cell recruitment is accelerated in males during AAA formation. To demonstrate that gonadal hormones can be used to modulate the inflammatory response accompanying AAA formation. Health and Human Services, Department of / National Institutes of Health 12/22/2010
AMERICAN PEST MANAGEMENT INC $135,400 Contract : Pest management services to support three renovation projects at the NIH. Health and Human Services, Department of / National Institutes of Health 3/02/2010
WASHINGTON STATE UNIVERSITY $83,349 Grant Trans-NIH Recovery Act Research Support: Herpes simplex virus (HSV) is a common and significant human pathogen that causes lifelong latent infection and a variety of diseases, ranging from cold sores and genital lesions to blindness and fatal encephalitis. Proteins within the tegument layer of H Health and Human Services, Department of / National Institutes of Health 3/24/2011
SRI INTERNATIONAL $8,000,000 Contract : Work Assignment 17: RECOVERY -'IN VIVO SCREENING OF COMBINATIONS OF DRUGS TO TREAT CANCER' We will test 121 drug combinations in three xenograft models. Test compounds and route of administration will be determined by the COTR. Tumor cell lines will be se Health and Human Services, Department of / National Institutes of Health 9/03/2010
WASHINGTON UNIVERSITY, THE $331,345 Grant Trans-NIH Recovery Act Research Support: The majority of diseases potentially amenable to gene-based therapeutic approaches will likely require systemic vector administration, such as pulmonary arterial hypertension (PAH). Impediments to practical application of Ad vectors to vascular diseases i Health and Human Services, Department of / National Institutes of Health 3/25/2011
NORTHERN ILLINOIS UNIVERSITY INC $30,972 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This project aims to examine the efficacy of targeting amino acid transporters ASCT2 and LAT1 in human hepatocellular carcinoma (HCC), a recalcitrant cancer with poor prognosis and limited treatment options. ASCT2 and Health and Human Services, Department of / National Institutes of Health 3/04/2011
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. $50,000 Grant Trans-NIH Recovery Act Research Support: The recent research from this laboratory provides direct evidencethat Drosophila is a suitable genetic model for studying molecular, cellular and neural basis of feeding behavioral control and eating disorders. We have shown that Drosophila neuropeptide F Health and Human Services, Department of / National Institutes of Health 3/22/2010
MOLECULAR TARGETING TECHNOLOGIES, INC. $176,838 Grant Trans-NIH Recovery Act Research Support: This proposal builds on our recent discovery that squaraine rotaxanes (SRs) are among the world's brightest and most stable fluorescent NIR dyes. However due to their poor solubility under aqueous conditions, their usefulness in biological applications re Health and Human Services, Department of / National Institutes of Health 7/15/2009
UNIVERSITY OF SOUTHERN CALIFORNIA $162,000 Grant Trans-NIH Recovery Act Research Support: The Animal Core of the Southern California Research Center for ALPD and Cirrhosis is the most critical component of the center which catalyzes research on in vivo genetic analysis and synergism between alcohol and co-morbidities for the pathogenesis of al Health and Human Services, Department of / National Institutes of Health 7/09/2010
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE $133,938 Grant Trans-NIH Recovery Act Research Support: While the positive association between socioeconomic status (SES) and health outcomes has been a consistent finding in health related research, the pathways that produce this association remain imperfectly understood. One pathway that has been hypothesize Health and Human Services, Department of / National Institutes of Health 3/15/2011
DUKE UNIVERSITY $421,645 Grant Trans-NIH Recovery Act Research Support: This project will examine how genetic differences relate to a diagnosis of MRI-defined vascular depression and in turn, severity of cerebral ischemic lesions. This study is relevant to older populations where approximately half of older depressed individ Health and Human Services, Department of / National Institutes of Health 5/19/2010
UNIVERSITY OF MASSACHUSETTS $113,898 Grant Trans-NIH Recovery Act Research Support: Antigen processing is an integral part of cell-mediated immune surveillance and responses that involve MHC- restriction and T cell recognition. Processed antigenic peptides, when presented on cell surface by MHC molecules to T cells, serve as identity tag Health and Human Services, Department of / National Institutes of Health 3/15/2011
YALE UNIVERSITY $83,998 Grant Trans-NIH Recovery Act Research Support: The recent resurgence of important infectious diseases has led to a need for K-12 school curricula that create a better understanding of disease transmission dynamics and their biological underpinnings. To produce these curricula, Lyme disease and West Ni Health and Human Services, Department of / National Institutes of Health 9/13/2010
EASTERN VIRGINIA MEDICAL SCHOOL $30,082 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The RAS signaling pathway controls cell growth, survival and death in all multicellular organisms. Deregulation of RAS proto-oncogenes is found in approximately 30% of human cancer. Thus an important goal in cancer bio Health and Human Services, Department of / National Institutes of Health 1/28/2011
BETH ISRAEL DEACONESS MEDICAL CENTER INC $52,836 Grant Trans-NIH Recovery Act Research Support: Mutations in the alpha-actinin-4 gene ACTN4 cause an autosomal dominant form of focal and segmental glomerulosclerosis (FSGS). ACTN4-mediated FSGS is dominant, adult onset, and slowly progressive, suggesting subtle time and stress dependent alterations in Health and Human Services, Department of / National Institutes of Health 2/11/2011
UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH $73,834 Grant Trans-NIH Recovery Act Research Support: This is a supplemental award for enhancing and accelerating our existed research: NIAID/NIH grant molecular basis for age-related thymic involution and rejuvenation (R01-AI081995). In the first year of this R01 project, we established a thymic medullary s Health and Human Services, Department of / National Institutes of Health 3/01/2011
OREGON STATE UNIVERSITY $292,400 Grant Trans-NIH Recovery Act Research Support: The Environmental Health Sciences (EHS) Center at Oregon State University is an interdisciplinary unit of 35 Center investigators and now in its 39th year of existence. The mission of the EHS Center is to foster excellent research and technology developme Health and Human Services, Department of / National Institutes of Health 9/27/2010
UNIVERSITY OF SOUTHERN CALIFORNIA $84,274 Grant Trans-NIH Recovery Act Research Support: Minichromosome maintenance protein (MCM) complex functions as a helicase that unwinds DNA to provide template for DNA replication and plays a critical role in regulating cell growth. MCM helicases are considered to be a licensing factor for cellular DNA r Health and Human Services, Department of / National Institutes of Health 8/31/2010
CARNEGIE MELLON UNIVERSITY $180,529 Grant Trans-NIH Recovery Act Research Support: The activities included in the parent grant, 1 R21 EB008804-01A2, which encompass those proposed in this supplemental request, are based on the implementation of the clinical research study from which data is gathered for the application of the FSI comput Health and Human Services, Department of / National Institutes of Health 7/15/2009
CARNEGIE MELLON UNIVERSITY $333,151 Grant Trans-NIH Recovery Act Research Support: Among the many problems arising from cell biology and medicine, shape phenotype mapping (the detailed measurement of shape related quantities from cells and subcellular organelles) from microscopy images has received particular attention in the past due t Health and Human Services, Department of / National Institutes of Health 9/30/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $866,489 Grant Trans-NIH Recovery Act Research Support: The majority of diseases potentially amenable to gene-based therapeutic approaches will likely require systemic vector administration, especially those with vascular involvement such as metastatic cancer, pulmonary arterial hypertension (PAH) and various Health and Human Services, Department of / National Institutes of Health 5/30/2009
LEHIGH UNIVERSITY $73,099 Grant Trans-NIH Recovery Act Research Support: The general hypothesis of this grant is non-spherical nanoparticles will enhance targeted delivery efficacy over spherical counterpart due to the dynamic tumbling and larger adhesion area. There are two specific aims: Specific Aim 1: The development of a Health and Human Services, Department of / National Institutes of Health 1/07/2011
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA $3,990,198 Grant Trans-NIH Recovery Act Research Support: The Center for Comparative Effectiveness in Genomic Medicine (CEGeM) is housed within the Abramson Cancer Center at the University of Pennsylvania and closely linked to the participating departments and centers at Penn. CEGeM brings together investigators Health and Human Services, Department of / National Institutes of Health 9/29/2009
LOMA LINDA UNIVERSITY $676,510 Contract : The use of pigs as organ donors for human transplantation represents a solution to the escalating shortage of organs that are available for patients with endstage diseases. Wild type pig organs are hyperacutely rejected, however, by preexisting natural an Health and Human Services, Department of / National Institutes of Health 8/30/2010
UNIVERSITY OF SOUTHERN CALIFORNIA $400,701 Grant Trans-NIH Recovery Act Research Support: Glutathione (GSH) is a key intracellular antioxidant that also modulates diverse critical cellular processes such as inflammatory and fibrogenic responses. Patients with chronic liver diseases have low hepatic GSH levels that up to now have mostly been a Health and Human Services, Department of / National Institutes of Health 7/15/2010
SAPIENT GOVERNMENT SERVICES, INC. $383,541 Contract : To acquire professional Information Technology (IT) services to support the National Institutes of Health national Database for Autism Research (NDAR) Progr;am in the areas of project management, system architecture, requirements agathering and system tes Health and Human Services, Department of / National Institutes of Health 5/28/2010
GATACA LLC $34,000 Grant Trans-NIH Recovery Act Research Support: Integrated Desktop Software for Management of Hepatitic C Data. This award was for adding crucial features to the software. Health and Human Services, Department of / National Institutes of Health 7/19/2010
MATTHEWS MEDIA GROUP, INC. $50,000 Contract : EXPANSION OF RESOURCES, AWARENESS, AND UTILIZATION OF NCI'S SMOKING CESSATION WEBSITE AND QUITLINE SERVICES Health and Human Services, Department of / National Institutes of Health 9/24/2010
DREXEL UNIVERSITY $76,959 Grant Trans-NIH Recovery Act Research Support: Amyotrophic lateral sclerosis (ALS) is characterized by the progressive and selective loss of motor neurons (MNs) in the motor cortex, brainstem, and spinal cord, resulting in death of patients 2-5 years after diagnosis. Glutamate-mediated excitotoxicity Health and Human Services, Department of / National Institutes of Health 9/06/2010
BECKMAN COULTER, INC. $24,080 Contract : J-26XPI, 200/208/204V, 50/60 Hz -- Catalog #: 393127; Product Service Code 6640; Product/Service Description:Laboratory Equipment & Supplies Health and Human Services, Department of / National Institutes of Health 12/08/2009
LOUISIANA STATE UNIVERSITY SYSTEM $343,122 Grant Trans-NIH Recovery Act Research Support: T cell?based therapies for cancer in the form of adoptive T cell transfer (ACT) or cancer vaccines can kill tumors expressing immunodominant tumor antigens. However, this process allows the escape of tumor cells expressing poorly immunogenic or subdomina Health and Human Services, Department of / National Institutes of Health 9/15/2010
UNIVERSITY OF ALABAMA AT BIRMINGHAM $295,606 Grant Trans-NIH Recovery Act Research Support: Tuberculosis is endemic among patients with AIDS and follows an aggressive course with poor localization of myobacteria into granuloma and widespread infection. Granulomas are monocyte rich collections of cells which derive from the circulating periphera Health and Human Services, Department of / National Institutes of Health 2/24/2011
ICF INCORPORATED, L.L.C. $497,489 Contract : Professional Information Technology (IT) Management Support Services to assist NIH OCIO with transparency and accountability for ARRA-funded enterprise IT projects within the NIH. Health and Human Services, Department of / National Institutes of Health 4/03/2010
CHILDRENS HOSPITAL OF PHILADELPHIA $80,951 Grant Trans-NIH Recovery Act Research Support: This application addresses the broad Challenge Area (15) Translational Sciences and specifically the challenge topic 15-DK-106 : Translating basic hematology concepts. Diamond Blackfan anemia is a rare bone marrow failure syndrome characterized by red ce Health and Human Services, Department of / National Institutes of Health 2/22/2011
OHIO STATE UNIVERSITY, THE $237,195 Grant Trans-NIH Recovery Act Research Support: The candidate's main objective is to establish a vigorous, independent research program centered on structure and function studies of HIV replication complexes. The new findings will be exploited to discover novel effective antiretroviral inhibitors. Sinc Health and Human Services, Department of / National Institutes of Health 1/24/2011
MOUNT SINAI SCHOOL OF MEDICINE $392,362 Grant Trans-NIH Recovery Act Research Support: Mutations in Leucine-rich-repeat-kinase 2 (LRRK2), are the MOST PREVALENT genetic causes in both familial and sporadic PD. To understand the pathogenic pathway and mechanisms, we have created a set of powerful tools to identify interacting proteins and su Health and Human Services, Department of / National Institutes of Health 2/23/2011
UNIVERSITY OF LOUISVILLE $50,710 Grant Trans-NIH Recovery Act Research Support: The candidate's overall career goal is to establish an independent research program devoted to investigating cellular mechanisms of proteinuric nephropathies, with an emphasis on diabetic nephropathy (DN). Currently, DN is the leading cause of end stage r Health and Human Services, Department of / National Institutes of Health 9/17/2009
BECKMAN COULTER, INC. $42,100 Contract : Recovery Act-Qte#48019876 - VI-CELL XR (Extended Range)Complete System; Item# 731050; deliver to Dr Charles Egwuagu/NIH/NEI/LI; Bldg 10/10N-116A, 10 Center Drive, Bethesda, MD 20892 Health and Human Services, Department of / National Institutes of Health 2/01/2010
EMORY UNIVERSITY $53,320 Grant Trans-NIH Recovery Act Research Support: Regulation of the Sodium chloride Cotransporter: The purpose of the funding is to investigate the regulation of this important effector of blood pressure control by kinases and second messengers. The Sodium Chloride Cotransporter is the site of action of Health and Human Services, Department of / National Institutes of Health 1/28/2011
NORTHEASTERN UNIVERSITY $307,546 Grant Trans-NIH Recovery Act Research Support: De Novo Synthesis for MedChem on Sugars Health and Human Services, Department of / National Institutes of Health 2/24/2011
UNIVERSITY OF MIAMI $157,776 Grant Trans-NIH Recovery Act Research Support: Opiate drug abuse and human immunodeficiency virus (HIV) are two major public health problems. Opiate drug abuse affects many people with substantial adverse impact on society. In the worldwide, more than 40 million people are currently infected with HIV. Health and Human Services, Department of / National Institutes of Health 2/16/2011
ULTRASOUND MEDICAL DEVICES, INC. $76,467 Grant Trans-NIH Recovery Act Research Support: The overall goal of the proposed research program is to design and develop a noninvasive device for accurately measuring arterial compliance. Arterial compliance has been shown to be a strong indicator of many types of vascular disease, including cardiova Health and Human Services, Department of / National Institutes of Health 2/02/2011
ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE $423,500 Grant Trans-NIH Recovery Act Research Support: The major goal of this proposal is to understand the molecular mechanism(s) of liver fibrosis by hepatitis C virus (HCV) infection. Hepatitis C virus (HCV) is the leading cause of chronic liver disease worldwide. HCV infection often leads to chronic hepat Health and Human Services, Department of / National Institutes of Health 5/15/2009
UNIVERSITY OF TEXAS AT AUSTIN $36,688 Grant Trans-NIH Recovery Act Research Support: Retinoic acid (RA) has several established functions during cardiac development, including actions in the fetal epicardium required for myocardial growth. An open question is if retinoid effects are limited to growth factor stimulation pathway(s) or if ad Health and Human Services, Department of / National Institutes of Health 1/24/2011
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON $499,826 Grant Trans-NIH Recovery Act Research Support: The leishmaniasis have significant global impact; 350 million people on 5 continents are at risk and an estimated 10?50 million people in endemic tropical and subtropical regions are affected. Hundreds of thousands of people have died in recent years in e Health and Human Services, Department of / National Institutes of Health 2/04/2011
SAINT LOUIS UNIVERSITY $75,546 Grant Trans-NIH Recovery Act Research Support: The major goals of this project are to define the role of TSHR in early thyrocyte commitment and identify the regulatory factors and molecular events involved in the specification of thyrocyte fate. These studies may have important implications not only f Health and Human Services, Department of / National Institutes of Health 3/14/2011
UNIVERSITY OF PITTSBURGH THE $132,000 Grant Trans-NIH Recovery Act Research Support: The project proposed in this supplement complements our experiments on drug development for Huntington's Disease with investigations on gene therapy. It will also accelerate the experimental agenda for drug discovery. The new strategy is to select drugs Health and Human Services, Department of / National Institutes of Health 3/04/2011
KESSLER FOUNDATION INC $153,854 Grant Trans-NIH Recovery Act Research Support: Of 5.7 million stroke survivors in the United States, up to 90% may have visuospatial deficits, linked to poor rehabilitation outcomes, an increase of clinical morbidity, and impairments in competent driving, shopping, sports, computer/internet use, and o Health and Human Services, Department of / National Institutes of Health 9/10/2009
TRUSTEES OF BOSTON UNIVERSITY $155,184 Grant Trans-NIH Recovery Act Research Support: IIkaros is a nuclear protein and key regulator of T lymphopoiesis. Ikaros deficiency in mice results in abnormal T cell development and, with 100% penetrance, T cell leukemogenesis. However, the mechanistic role of Ikaros in these events is not yet known. Health and Human Services, Department of / National Institutes of Health 2/07/2011
CHESTNUT HEALTH SYSTEMS, INC. $369,875 Grant Trans-NIH Recovery Act Research Support: Comprehensive and standardized biopsychosocial assessments are a key piece of infrastructure in the drive towards evidence-based and effective substance abuse treatment. Demands to cover more areas and constructs mean that such assessments can take 1-2 ho Health and Human Services, Department of / National Institutes of Health 5/01/2009
UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL $98,672 Grant Trans-NIH Recovery Act Research Support: This Administrative Supplement under the American Recovery and Reinvestment Act of 2009 was requested to enhance the education and research of trainees supported by Bridge to the Doctorate Award 2R25 GM058389. This supplement is being used to purchase a Health and Human Services, Department of / National Institutes of Health 7/15/2009
UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL $199,282 Grant Trans-NIH Recovery Act Research Support: A transgenic murine model of melanoma was developed by the ectopic expression of metabotropic glutamate receptor 1 (murine GRM1 or mGRM1) in melanocytes. We have expanded these original studies and have now shown that over 65% of human melanomas express t Health and Human Services, Department of / National Institutes of Health 9/08/2009
KALAMAZOO COLLEGE $123,943 Grant Trans-NIH Recovery Act Research Support: Cytochrome P450 enzymes in humans are a family of heme-containing enzymes involved in metabolism of steroids, vitamins, eiconsanoids, and xenobiotics such as drugs, complex plant alkaloids, carcinogens, and other small molecules. With the sequencing of th Health and Human Services, Department of / National Institutes of Health 7/17/2009
NEW YORK MEDICAL COLLEGE $659,850 Grant Trans-NIH Recovery Act Research Support: Two hundred million people world wide are affected by thyroid proliferative diseases (TPD), which include goiter, cancer and adenoma. Women are three times more susceptible than men and overall the incidence of thyroid dysfunction occurring in one in eigh Health and Human Services, Department of / National Institutes of Health 6/02/2009
ANC RESEARCH & DEVELOPMENT, LLC $648,929 Contract : Purchase of Leica TCS SP5 II Multi-Photon & Spectral Confocal System Health and Human Services, Department of / National Institutes of Health 8/31/2010
WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY $409,749 Contract : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula Health and Human Services, Department of / National Institutes of Health 8/04/2009
HEALTHPARTNERS RESEARCH FOUNDATION $853,730 Grant Trans-NIH Recovery Act Research Support: Computer Assisted Guidance for Tobacco Dependence Interventions in Dental Offices Electronic health records (EDR) represent a powerful tool for incorporating best practice guidelines into the dental treatment encounter through the use of clinical decisio Health and Human Services, Department of / National Institutes of Health 9/22/2009
POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY $99,632 Grant Trans-NIH Recovery Act Research Support: This American Recovery and Reinvestment Act (ARRA) supplement seeks to establish an instrumentation facility to accelerate development of morpholino (MO) microarray technology pursued under the parent award. The proposed instrument will document history o Health and Human Services, Department of / National Institutes of Health 9/30/2009
UNIVERSITY OF WASHINGTON $110,000 Grant Trans-NIH Recovery Act Research Support: Non-invasive techniques for imaging blood flow - down to capillary-level resolution - are of paramount importance in order to research and diagnose diseases that have vascular etiology or involvement. Current optical imaging techniques are able to achieve Health and Human Services, Department of / National Institutes of Health 4/22/2011
UNIVERSITY OF PITTSBURGH THE $203,529 Grant Trans-NIH Recovery Act Research Support: We originally cloned SAFB1 as a transcriptional repressor, and it has since been implicated in a number of processes including hormone response, and transformation. The SAFB1 gene shows extremely high rates of loss of heterozygosity in breast cancer, and Health and Human Services, Department of / National Institutes of Health 5/10/2011
ALARM SECURITY GROUP LLC $2,194,000 Contract : BARRIER DOOR SECURITY SERVICES. Health and Human Services, Department of / National Institutes of Health 3/25/2010
TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER $204,260 Grant Trans-NIH Recovery Act Research Support: Many human genetic diseases are caused by mutations that result in alteration of protein-protein interactions, including spinal muscular atrophy (SMA). Mutations in SMN protein cause disruption of SMN complexes, including SMN-ZPR1 complexes in patients wi Health and Human Services, Department of / National Institutes of Health 4/06/2011
HARVARD COLLEGE, PRESIDENT & FELLOWS OF $481,212 Grant Trans-NIH Recovery Act Research Support: One of the greatest challenges in biochemistry is to study dozens to hundreds of molecules simultaneously using single cells or in single cell types obtained from complex, living tissue. Here, we propose a new technology, termed ?microlysis technology?, w Health and Human Services, Department of / National Institutes of Health 9/25/2010
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. $378,708 Grant Trans-NIH Recovery Act Research Support: Streptococcus pneumoniae (S.p.), an important human pathogen causing pneumonia, is a major cause of morbidity and mortality worldwide. Its early mortality rate still remains the highest when compared to the pre-antibiotic era. Pneumolysin (PLY), a key cyt Health and Human Services, Department of / National Institutes of Health 9/12/2009
UNIVERSITY OF PITTSBURGH THE $215,672 Grant Trans-NIH Recovery Act Research Support: This is a competitive supplement awarded through the American Recovery and Reinvestment Act mechanism to expand the goals of the parent U01. Quantitative MS assays for the INIA-West gene target proteins will be developed to facilitate high-throughput quan Health and Human Services, Department of / National Institutes of Health 4/08/2011
GENERAL ELECTRIC COMPANY $1,848,540 Grant Trans-NIH Recovery Act Research Support: Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to enviromental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driven by the yet unmet need for wea Health and Human Services, Department of / National Institutes of Health 9/03/2009
UNIVERSITY OF ARKANSAS SYSTEM $132,611 Grant Trans-NIH Recovery Act Research Support: The goals of this project are to identify relevant pathways that mediate the progression of biliary cirrhosis, with a focus on those specific to bile duct epithelia and portal fibroblasts. Health and Human Services, Department of / National Institutes of Health 5/05/2011
OREGON HEALTH & SCIENCE UNIVERSITY $110,387 Grant Trans-NIH Recovery Act Research Support: Glaucoma is a leading cause of blindness in the United States and worldwide. Technologies to aid in the diagnosis and monitoring of glaucoma are of particular importance because the onset of disease is insidious and the visual damage is irreversible. Th Health and Human Services, Department of / National Institutes of Health 5/03/2011
LOCKHEED MARTIN ASPENMED SERVICES, INC $851,102 Contract : Validation of Universal Influenza Vaccine Assay Health and Human Services, Department of / National Institutes of Health 4/01/2010
GENERAL ELECTRIC COMPANY $1,238,601 Grant Trans-NIH Recovery Act Research Support: By coupling a disruptive technology, Digital Micro-Printing (DMP) with advances in miniature, low-cost electronics, the project team will improve access to Point-of-Care ultrasound for Maternal Health thereby reducing healthcare disparities, and enabling Health and Human Services, Department of / National Institutes of Health 9/23/2009
TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $497,557 Grant Trans-NIH Recovery Act Research Support: The human body encounters most pathogens through mucosal sites. Two main portals are the lung and gut, where pathogens are encountered through the aerodigestive tract mucosa and oral ingestion, respectively. While both of these organs harbor resident immu Health and Human Services, Department of / National Institutes of Health 9/27/2010
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE $69,588 Grant Trans-NIH Recovery Act Research Support: The cerebellum is critical for motor coordination and cognitive function. Granule neurons are a key component of cerebellar circuitry and are thought to represent the cell of origin for the pediatric brain tumor medulloblastoma. Although the development Health and Human Services, Department of / National Institutes of Health 6/21/2011
JOHNS HOPKINS UNIVERSITY, THE $455,083 Grant Trans-NIH Recovery Act Research Support: We are conducting an economic evaluation of a depression intervention Beat the Blues (BTB). Beat the Blues is being tested in a randomized trial funded by NIMH (R01 MH079814). The intervention involves up to 10 sessions (combination of home and telephone Health and Human Services, Department of / National Institutes of Health 6/20/2011
MAGEE-WOMENS HEALTH CORPORATION $311,334 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The purpose of this proposal is to demonstrate the capabilities of the University of Pittsburgh to participate as a Clinical site in a NICHD-sponsored network addressing Preterm Birth in Nulliparous Women (Nullipara Ne Health and Human Services, Department of / National Institutes of Health 7/08/2010
EMORY UNIVERSITY $187,500 Grant Trans-NIH Recovery Act Research Support: DOPAMINERGIC MODULATION OF COGNITIVE ASPECTS OF SKILL ACQUISITION IN PARKINSON'S DISEASE DOPAMINERGIC MODULATION OF COGNITIVE ASPECTS OF SKILL ACQUISITION IN PD ParkinsonG??s disease (PD) is characterized by cardinal motor features considered reflective o Health and Human Services, Department of / National Institutes of Health 5/15/2009
AMERICAN PEST MANAGEMENT INC $135,400 Contract : Pest management services to support three renovation projects at the NIH. Health and Human Services, Department of / National Institutes of Health 3/02/2010
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL $265,937 Grant Trans-NIH Recovery Act Research Support: This ARRA supplement was received in order to hire a computer programming specialist to develop tools for analysis of genetic and genomic information within the Utah Genome Center databases. These tools will be publicly available on the Utah genome Center Health and Human Services, Department of / National Institutes of Health 6/30/2010
UNIVERSITY OF FLORIDA $219,658 Grant Trans-NIH Recovery Act Research Support: This proposal expands the research scope of the parent grant (R01 AG033906) by investigating biological markers reflecting predisposing factors for and the stress-related consequences of chronic pain. Consistent with the OppNet priorities, this proposal t Health and Human Services, Department of / National Institutes of Health 9/01/2010
UNIVERSITY OF UTAH, THE $66,511 Grant Trans-NIH Recovery Act Research Support: In this project, we will use novel mathematical algorithms and state-of-the-art software tools to create comparative and integrative models from TCGA cancer genomic data and computationally predict the outcome of cancers. Adding the TCGA controlled-access Health and Human Services, Department of / National Institutes of Health 5/25/2011
UNIVERSITY OF CALIFORNIA, LOS ANGELES $456,523 Grant Trans-NIH Recovery Act Research Support: The goal of this ARRA project is to develop a multivariate quantitative template of the developing brain. The template will be openly available to all and will be used to enumerate the interaction between working memory performance and cortical and connec Health and Human Services, Department of / National Institutes of Health 5/12/2011
ALABAMA A & M UNIVERSITY $139,755 Grant Trans-NIH Recovery Act Research Support: This Grant provides a research experience for two college graduate students and a consultant/technician in health-related scientific research in maintaining E.coli culture and mutant generation. Health and Human Services, Department of / National Institutes of Health 6/03/2011
ALBANY MEDICAL COLLEGE $4,640,929 Grant Trans-NIH Recovery Act Research Support: Overall Project : Francisella tularensis is considered to be a Category A agent by the NIAID because of its extreme infectivity, ease of dissemination, and substantial capacity to cause illness and death. This Program Project brings together a diverse gro Health and Human Services, Department of / National Institutes of Health 8/13/2009
GOVERNORS STATE UNIVERSITY $442,011 Grant Trans-NIH Recovery Act Research Support: The objective of this proposal is to examine outcomes of a treatment intervention designed to increase functional use of complex (multi-clausal) sentences in school-age students with primary language impairments that impact literacy and academic achieveme Health and Human Services, Department of / National Institutes of Health 6/09/2010
TRUSTEES OF DARTMOUTH COLLEGE $788,447 Grant Trans-NIH Recovery Act Research Support: The hemoglobinopathies comprise the most prevalent class of human genetic diseases. Those involving the ?-globin locus include ?-thalassemia and sickle cell disease (SCD). A variety of observations and experimental results indicate that strategies designe Health and Human Services, Department of / National Institutes of Health 6/01/2009
WISTAR INSTITUTE OF ANATOMY & BIOLOGY $160,609 Grant Trans-NIH Recovery Act Research Support: The PI's previous work unveiled a novel mechanism of vascularization in human and mouse ovarian carcinoma: beta-defensins were shown to massively recruit CD45+CD11c+CCR6+ myeloid cells to the tumor microenvironment, where they were transformed by VEGF in Health and Human Services, Department of / National Institutes of Health 5/25/2011
WAKE FOREST UNIVERSITY $47,998 Grant Trans-NIH Recovery Act Research Support: This grant proposal offers an effective approach to tackle fecal incontinence. We were able to successfully implant bioengineered rings that were constructed from IAS smooth muscle cells and neuronal precursor cells. In essence we have developed intrinsic Health and Human Services, Department of / National Institutes of Health 9/20/2011
WAYNE STATE UNIVERSITY (INC) $878,802 Grant Trans-NIH Recovery Act Research Support: The first aim is to relate signaling intermediates in the MAPK pathway to activity-dependent gene induction and changes in synaptic organization in human epileptic neocortex. The second is to use an eplieptic model in the rat to determine the functional Health and Human Services, Department of / National Institutes of Health 7/20/2009
J.DAVID GLADSTONE INSTITUTES, THE $370,985 Grant Trans-NIH Recovery Act Research Support: Pathway-oriented visualization of genomic information enables biologists to interpret data in the context of biological processes and systems. We developed GenMAPP (Gene Map Annotator and Pathway Profiler) as a free, open-source, stand-alone computer prog Health and Human Services, Department of / National Institutes of Health 8/14/2009
4S3 BIOSCIENCE INC. $336,682 Grant Trans-NIH Recovery Act Research Support: Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. Generation of the protein fusion will be followed by testing its activity in cell lines from human patients, ultimately testing its efficacy in mou Health and Human Services, Department of / National Institutes of Health 7/20/2009
GLOBAL CONSULTING INC. $497,000 Contract : Award for industrial hygiene services throughout the NIH campus in Bethesda, MD Health and Human Services, Department of / National Institutes of Health 3/30/2010
UNIVERSITY OF HOUSTON SYSTEM $422,033 Grant Trans-NIH Recovery Act Research Support: The homeostatic balance between proliferation and apoptosis is essential for the intestinal epithelium to function as a physiological and structural barrier. Intestinal epithelial cells have a high rate of cell turnover accompanied by an equally high rate Health and Human Services, Department of / National Institutes of Health 4/11/2011
UNIVERSITY OF ALABAMA AT BIRMINGHAM $592,990 Grant Trans-NIH Recovery Act Research Support: Despite many studies that have aimed to alleviate the effects of periodontal and endodontic disease there is still an urgent need to improve the oral health of those suffering from oral infectious or inflammatory diseases. Such translational application o Health and Human Services, Department of / National Institutes of Health 4/28/2011
METHODIST HOSPITAL RESEARCH INSTITUTE, THE $1,878,342 Grant Trans-NIH Recovery Act Research Support: The overall goal of this initiative is to investigate the cellular uptake, trafficking, and sub-cellular localization of different classes and subtypes of nanoparticles (NPs) with well-defined physiochemical properties for the creation of a reference tabl Health and Human Services, Department of / National Institutes of Health 5/02/2011
UNIVERSITY OF CALIFORNIA, SAN DIEGO $64,804 Grant Trans-NIH Recovery Act Research Support: Many NLP applications have been successfully developed to extract information from text. Most of the applications have focused on identifying individual clinical conditions in textual records, which is the first step in making the conditions available to Health and Human Services, Department of / National Institutes of Health 5/02/2011
CHESTNUT HEALTH SYSTEMS, INC. $369,875 Grant Trans-NIH Recovery Act Research Support: Comprehensive and standardized biopsychosocial assessments are a key piece of infrastructure in the drive towards evidence-based and effective substance abuse treatment. Demands to cover more areas and constructs mean that such assessments can take 1-2 ho Health and Human Services, Department of / National Institutes of Health 5/01/2009
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS $100,732 Grant Trans-NIH Recovery Act Research Support: Progress in biomedical research and its translation into clinical practice require the integration of data across multiple scales (molecules, cells, organisms), organism types, and fields of research. The need for data integration is especially acute in i Health and Human Services, Department of / National Institutes of Health 4/29/2011
ANCHORAGE MUSEUM ASSOCIATION $199,982 Grant Trans-NIH Recovery Act Research Support: This administrative supplement seeks to enhance an existing NCRR SEPA grant titled North Star (Phases I and II), the aims of which include; 1) increasing the number of Alaskans from educationally and/or economically disadvantaged backgrounds, particularly Health and Human Services, Department of / National Institutes of Health 8/28/2009
BAYLOR COLLEGE OF MEDICINE $28,796 Grant Trans-NIH Recovery Act Research Support: Epileptic seizures during the first weeks of human life are very common and are associated with severe Morbidity and Mortality. Research conducted under the parent grant for this proposed administrative supplement is aimed at the development of new treatm Health and Human Services, Department of / National Institutes of Health 4/29/2011
VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY $998,255 Grant Trans-NIH Recovery Act Research Support: Little is known about the basic mechanisms of medical decision-making, or in fact any decision making in similar sorts of high-dimensional environment. We propose that these environments, paired with the social conditions around expertise lend themselves Health and Human Services, Department of / National Institutes of Health 4/29/2011
THE CLEVELAND CLINIC FOUNDATION $1,627,009 Contract : We have been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically to establish a Tissue Source Site (TSS) Network capable of delivering clinically annotated biospecimens through either or both retr Health and Human Services, Department of / National Institutes of Health 9/27/2010
GENERAL ELECTRIC COMPANY $1,613,729 Grant Trans-NIH Recovery Act Research Support: Driven by advances in electronic miniaturization, probe construction techniques and computing power, medical ultrasound is experiencing a trend toward smaller, lower cost systems with real-time volumetric imaging capabilities. These new attributes provide Health and Human Services, Department of / National Institutes of Health 7/16/2009
CREIGHTON UNIVERSITY $583,167 Grant Trans-NIH Recovery Act Research Support: Recently bone quality has been widely realized to be more predictive for risk of fragility fractures than bone mineral density (BMD). Our parent R01 human study (R01AR04054496) is to characterize defects in bone quality, independent of bone mass, that con Health and Human Services, Department of / National Institutes of Health 9/29/2009
PENNSYLVANIA STATE UNIVERSITY, THE $301,159 Grant Trans-NIH Recovery Act Research Support: The Role of Zinc Finger Genes in Leukemogenesis: The objective of the proposed study is to understand normal hematopoiesis and the malignant transformation of hematopoietic cells by identifying the biological functions of Ikaros proteins. Ikaros is essent Health and Human Services, Department of / National Institutes of Health 4/07/2011
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY $108,890 Grant Trans-NIH Recovery Act Research Support: Health Disparities, Building trust between researchers and communities through capacity building in Environmental Public Health. : 09-ES-101* Increasing Capacity and Public Trust: A Strategy to Build Effective Sustainable Community- Academic Partnerships Health and Human Services, Department of / National Institutes of Health 12/30/2011
NEW YORK UNIVERSITY (INC) $38,625 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): To investigate the therapeutic implications of the current paradigm that autoimmune disease can result from defects in the clearance of dying/apoptotic cells, we have conducted preliminary studies that have shown that Health and Human Services, Department of / National Institutes of Health 7/18/2011
UNIVERSITY OF FLORIDA $95,508 Grant Trans-NIH Recovery Act Research Support: Myotonic dystrophy type 1 (DM1) is caused by a CTG expansion mutation located in the 3' untranslated portion of the dystrophica myotonica protein kinase gene. The identification and characterization of RNAbinding proteins that interact with expanded CUG r Health and Human Services, Department of / National Institutes of Health 8/22/2011
UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $138,369 Grant Trans-NIH Recovery Act Research Support: De-differentiation of adult somatic cells into multipotent progenitor cells might provide an attractive and alternative source for therapeutic cloning to generate pluripotent, autologous stem cells for regenerative medicine. Currently, the benefit of adul Health and Human Services, Department of / National Institutes of Health 9/02/2011
UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL $860,173 Grant Trans-NIH Recovery Act Research Support: This application addresses broad challenge area (04), clinical research, and specific challenge topic 05-CA-104, comparative effectiveness research on cancer treatment. One in six American men will be diagnosed with prostate cancer in their lifetime. Wh Health and Human Services, Department of / National Institutes of Health 9/29/2009
ADVANCED TARGETING SYSTEMS $3,000,000 Grant Trans-NIH Recovery Act Research Support: Pain due to cancer is one of the great fears, at times greater than even death, in the progression of the disease. Numerous studies have shown the preponderance of pain in terminal cases. But even worse, many times this pain is refractory to the last stan Health and Human Services, Department of / National Institutes of Health 9/01/2010
WAYNE STATE UNIVERSITY (INC) $1,002,772 Grant Trans-NIH Recovery Act Research Support: We propose a phase II trial that combines pimary oncologist's choice of chemotherapy (ChemoT) Consisting of 4 cycles or 4 months of followed by lymphodepletion with low dose fludarabine (Flu) and Cyclophosphamide (Cy) before giving multiple influsions of Health and Human Services, Department of / National Institutes of Health 7/16/2009
UNIVERSITY OF SOUTH FLORIDA $30,400 Grant Trans-NIH Recovery Act Research Support: This project is intended to develop capacity in Bolivia, Peru and Argentina, to carry out research in remote locations taking advantage of a large population that remains unexposed to treatment with neuroleptics during much or all of the course of schizop Health and Human Services, Department of / National Institutes of Health 7/20/2011
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE $27,058 Grant Trans-NIH Recovery Act Research Support: According to the most recent UNAIDS/WHO report, an estimated 33 million people worldwide were living with AIDS at the end of 2007, which caused 2 million deaths in 2008 alone. The effectiveness of the standard treatment for HIV infection, which consist of Health and Human Services, Department of / National Institutes of Health 9/16/2011
BAYLOR COLLEGE OF MEDICINE $61,877 Grant Trans-NIH Recovery Act Research Support: Malignant glioma is the most common and lethal primary brain tumor. Despite the improvement of imaging technology and surgical removal of the tumors significantly reduces the mortality of malignant glioma, how to enhance the sensitivity to radiation and c Health and Human Services, Department of / National Institutes of Health 7/27/2011
TEXAS CHRISTIAN UNIVERSITY INC $25,390 Grant Trans-NIH Recovery Act Research Support: This ARRA supplement (3R01GM064560-09S1) supports a project entitled ?Molecular Recognition in Dendrimers?. This program supports fundamental inquiries into the use of triazine dendrimers for the long term goal of drug delivery. Pursuant to these activi Health and Human Services, Department of / National Institutes of Health 9/30/2009
JOHNS HOPKINS UNIVERSITY, THE $109,006 Grant Trans-NIH Recovery Act Research Support: This project addresses two major bioinformatics problems: the development of better software for finding genes in eukaryotic genome sequences, and the development of genome assemblers for large shotgun sequencing projects. The gene finding project will pu Health and Human Services, Department of / National Institutes of Health 9/28/2011
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON $53,298 Grant Trans-NIH Recovery Act Research Support: p12CDK2AP1 Regulation of Normal and Neoplastic Growth. Administrative supplement to a parent K01 NCI Career Development Award to promote diversity. This supplement allows retention of one technical personnel, and this has significantly accelerated the pac Health and Human Services, Department of / National Institutes of Health 6/23/2011
UNIVERSITY OF MASSACHUSETTS $37,561 Grant Trans-NIH Recovery Act Research Support: Non-Hodgkin lymphoma (NHL) is the fifth most common cause of cancer death in the United States with a five-year survival rate of 64% overall (1996-03). Despite the promise of prognostic immune signatures, measurement of gene expression using microarrays i Health and Human Services, Department of / National Institutes of Health 4/13/2011
UNIVERSITY OF FLORIDA $359,579 Grant Trans-NIH Recovery Act Research Support: A central interest in developmental, reproductive, and stem biology is how common precursor cells acquire instruction to differentiate into specialized cell types in various organs. Understanding how cell fates are determined not only satisfies the curios Health and Human Services, Department of / National Institutes of Health 9/07/2011
UNIVERSITY OF WASHINGTON $1,453,104 Grant Trans-NIH Recovery Act Research Support: Comparative effectiveness research (CER) primarily involves estimation of causal effects of alternativetreatments on outcomes. To this end, observational databases are a promising source of information onpatient-level treatments and outcomes. However, obs Health and Human Services, Department of / National Institutes of Health 8/01/2011
VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY $189,334 Grant Trans-NIH Recovery Act Research Support: Cognitive behavioral treatments (CBT) available for addiction produce efficacious and replicable results. However, those results provide considerable opportunity for increases in efficacy. CBT assumes that changes in cognition and improvement in relevant Health and Human Services, Department of / National Institutes of Health 9/19/2011
WAYNE STATE UNIVERSITY (INC) $177,822 Grant Trans-NIH Recovery Act Research Support: Patient navigation (PN) is a widely used intervention approach in initiatives to reduce cancer health disparities and facilitate access to care, particularly in African American (AA) populations. However, the results of PN vary and little is known about t Health and Human Services, Department of / National Institutes of Health 9/01/2011
UNIVERSITY OF CHICAGO, THE $337,850 Grant Trans-NIH Recovery Act Research Support: Patient navigation (PN) is a community-centered approach that can potentially reduce health disparities by enhancing access to care at an earlier stage of the disease continuum for underserved populations, such as racial/ethnic minorities or individuals w Health and Human Services, Department of / National Institutes of Health 8/10/2011
NATIONAL OPINION RESEARCH CENTER $618,494 Grant Trans-NIH Recovery Act Research Support: The purpose of this grant is to build and test a data storage and dissemination system for confidential data, which obviates the need for users to build and secure their own computing environments. Recent advances in public utility (or 'cloud') computing Health and Human Services, Department of / National Institutes of Health 7/27/2011
METROPOLITAN STATE COLLEGE OF DENVER $142,844 Grant Trans-NIH Recovery Act Research Support: This award provides supplemental instruction and is a component of Academic Support offered on an institutional basis to students in the STEPS (Strides Toward Encouraging Professions in Science) Program (Funded by the Bridges to the Future Initiative from Health and Human Services, Department of / National Institutes of Health 4/06/2010
UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) $559,803 Grant Trans-NIH Recovery Act Research Support: Award Description: Purpose of the grant is to examine the relationship between EPO and the downstream transcriptional pathways that are necessary to control neuronal survival and inflammatory microglial activation and proliferation during oxidative stress Health and Human Services, Department of / National Institutes of Health 9/21/2011
OHIO STATE UNIVERSITY, THE $118,408 Grant Trans-NIH Recovery Act Research Support: Inadequate recruitment of eligible subjects for clinical trials is a major impediment to the advancement of medicine. Use of an EHR-based, point-of-care Clinical Trial Alert (CTA) approach has been shown to significantly improve recruitment in a prior stu Health and Human Services, Department of / National Institutes of Health 9/28/2011
UNIVERSITY OF WISCONSIN SYSTEM $148,500 Grant Trans-NIH Recovery Act Research Support: Every year, thousands of humans suffer traumatic brain injury (TBI) and most of the survivors manifest moderate to severe neurological dysfunction. Currently no known therapies that can prevent secondary neuronal death and/or promote neurological recovery Health and Human Services, Department of / National Institutes of Health 9/20/2009
CHILDREN'S HOSPITAL MEDICAL CENTER $30,298 Grant Trans-NIH Recovery Act Research Support: This supplemental project grant supports a new collaboration between the PI's lab and the lab of Dr. Michael Lovett at Washington University to identify the mutant gene responsible for the cleft lip and cleft palate phneotype in the Twirler mutant mice. B Health and Human Services, Department of / National Institutes of Health 7/25/2011
PTC THERAPEUTICS, INC. $996,430 Grant Trans-NIH Recovery Act Research Support: Severe hemophilia A and B (HA/HB) are disabling and life-threatening orphan disorders caused by a genetic defect. No treatments to correct this genetic defect are available. In previous studies in animals and humans, ataluren has shown the potential to tr Health and Human Services, Department of / National Institutes of Health 9/28/2009
UNIVERSITY OF ALABAMA AT BIRMINGHAM $380,141 Grant Trans-NIH Recovery Act Research Support: The overall goal of this study is to understand the mechanism underlying transcription factors specifying osteoclast lineage commitment and differentiation. This proposal is highly significant since elucidating osteoclast lineage commitment and differenti Health and Human Services, Department of / National Institutes of Health 8/08/2011
UNIVERSITY OF NEW MEXICO $179,331 Grant Trans-NIH Recovery Act Research Support: The potential role of extracellular proteases, namely the plasminogen activator/ plasminogen (PA/plgn) system in synaptic remodeling in the injured spinal cord of rodents will be the focus of these studies. The PA/plgn system has been suggested to play a Health and Human Services, Department of / National Institutes of Health 8/11/2011
WAYNE STATE UNIVERSITY (INC) $909,524 Grant Trans-NIH Recovery Act Research Support: Aim 1. We will define the structural and biological basis for the shedding of mRANKL by MT1-MMP. - Aim 1.1. Investigate the structural basis of MT1-MMP shedding of mRANKL; - Aim 1.2. Identify MT1-MMP/mRANKL complexes at the surface of pc cells. Aim 2. We Health and Human Services, Department of / National Institutes of Health 7/17/2009
WAYNE STATE UNIVERSITY (INC) $894,493 Grant Trans-NIH Recovery Act Research Support: The aim of our study is to compare the effectiveness of three complementary and alternative medicine therapies in reducing the level of stress and anxiety in pediatric patients, ages 1-12 years, undergoing sedation for imaging studies and importantly redu Health and Human Services, Department of / National Institutes of Health 9/16/2009
WAYNE STATE UNIVERSITY (INC) $441,552 Grant Trans-NIH Recovery Act Research Support: We propose to use use probabilistic tractography to quantify the strength of the arcuate fasiculus, and we hypothesize that this technique can be used as a biomarker to designate children with developmental delay who unlikely to make full recovery, thus a Health and Human Services, Department of / National Institutes of Health 9/17/2009
TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER $286,121 Grant Trans-NIH Recovery Act Research Support: Parkinson's disease (PD) is a neurodegene Parkinson's disease (PD) is a neurodegenerative disorder occurring after an extensive loss of midbrain dopamine (DA) neurons that regulate normal body movements. The small protein, D-synuclein (a-Syn), is implicat Health and Human Services, Department of / National Institutes of Health 9/24/2011
UNIVERSITY OF CALIFORNIA, IRVINE $312,113 Grant Trans-NIH Recovery Act Research Support: Heart failure (HF), obesity, and diabetes mellitus (DM) often co-exist and are associated with the development and progression of cardiovascular disease, functional disability, increased symptoms, and diminished quality of life (QOL). Nutritional manageme Health and Human Services, Department of / National Institutes of Health 8/14/2011
TRUSTEES OF INDIANA UNIVERSITY $34,375 Grant Trans-NIH Recovery Act Research Support: The proper organization of the mitotic spindle is critical to the accurate segregation of the genetic material; therefore understanding the molecular mechanisms of spindle assembly may allow for the identification of new targets for therapeutic developmen Health and Human Services, Department of / National Institutes of Health 9/15/2010
WAYNE STATE UNIVERSITY (INC) $402,400 Grant Trans-NIH Recovery Act Research Support: The rat respiratory system is an excellent model for experimental design in addressing respiratory-related issues that arise from injury. The C2 hemisection is a reliable and simple model employed in SCI research on the respiratory system. In this model, Health and Human Services, Department of / National Institutes of Health 9/30/2009
UNIVERSITY OF ILLINOIS $55,643 Grant Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to accelerate the pace of research in the current K08 grant. By its nature, the K-series grants provide generous support for the salary recovery of the principal investigator but limited resources for addi Health and Human Services, Department of / National Institutes of Health 9/30/2009
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. $1,006,212 Grant Trans-NIH Recovery Act Research Support: There is an urgent need to develop more effective vaccines and antibiotic regimens against many of the Select Agent bacteria that cause lethal infection in humans. This is particularly true for the candidate bioterrorism agents, Burkholderia. pseudomallei Health and Human Services, Department of / National Institutes of Health 7/05/2011
YALE UNIVERSITY $74,390 Grant Trans-NIH Recovery Act Research Support: Recent advances in cell culture studies provide invaluable insights on how the endothelial lineage is modulated by diverse signaling pathways. However, the cellular and molecular mechanisms that regulate the initial specification of endothelial lineage wi Health and Human Services, Department of / National Institutes of Health 9/10/2011
UNIVERSITY OF TEXAS AT AUSTIN $178,772 Grant Trans-NIH Recovery Act Research Support: The proposed study will initiate a new collaboration and advance the theme of our current studies on genetic instability in translocation-related human cancers. There are unstable regions of the human genome that are 'hotspots' for deletions and transloca Health and Human Services, Department of / National Institutes of Health 7/19/2011
UNIVERSITY OF SAN DIEGO $353,376 Grant Trans-NIH Recovery Act Research Support: The research plan involves the development of the copper-catalyzed diboration of carbonyls and imines. The synthetic utility of the resulting diboration products will be established to provide access to challenging functional group arrays. Health and Human Services, Department of / National Institutes of Health 8/19/2011
MOLECULAR EXPRESS INC $197,977 Grant Trans-NIH Recovery Act Research Support: The Company has been developing a new approach to immunization for herpes simplex virus type 2 (HSV2) infections that combines a unilamellar liposome carrier with a recombinant protein system that is capable of being engineered to express selected antigen Health and Human Services, Department of / National Institutes of Health 5/11/2010
STOWERS INSTITUTE FOR MEDICAL RESEARCH $238,500 Grant Trans-NIH Recovery Act Research Support: A prominent cause of deafness is loss of hair cells due to age, noise or antibiotic treatments. In contrast to mammalian hair cells, fish, bird and amphibian hair cells are constantly turning over and regenerating following hair cell death. The aim is to Health and Human Services, Department of / National Institutes of Health 9/17/2009
ANCHORAGE MUSEUM ASSOCIATION $131,182 Grant Trans-NIH Recovery Act Research Support: This administrative supplement seeks to enhance an existing NCRR SEPA grant titled North Star (Phases I and II), the aims of which include; 1) increasing the number of Alaskans from educationally and/or economically disadvantaged backgrounds, particularly Health and Human Services, Department of / National Institutes of Health 6/16/2011
WASHINGTON UNIVERSITY, THE $296,250 Grant Trans-NIH Recovery Act Research Support: The mandate to realize surrogate endpoints in the context of human clinical trials with conditionally replicative adenovirus (CRAd) agents has thus suggested the utility of imaging analysis. In theory, this type of assay could provide critical information Health and Human Services, Department of / National Institutes of Health 8/16/2011
SYNTHOSYS LLC $91,131 Contract : Synthosys provided consulting services in support of the STAR METRICS program, intended to help the federal government document the value of its investments in research and development in order to yield a more rigorous, transparent review of how our scien Health and Human Services, Department of / National Institutes of Health 8/10/2010
UNIVERSITY OF WISCONSIN SYSTEM $247,168 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application addresses broad challenge area (05) Comparative Effectiveness Research and specific challenge topic, 05-CA-104: Comparative Effectiveness Research on Cancer Treatment. Broad Objectives: The long-term Health and Human Services, Department of / National Institutes of Health 9/20/2011
OHIO STATE UNIVERSITY, THE $85,888 Grant Trans-NIH Recovery Act Research Support: This R01 was awarded to Dr. Peter Mohker, Ph.D., as a new investigator to study the role of ankyrin polypeptides for voltage-gated targeting in primary cardiomyocytes, and to identify how dysfunction in the pathway results in potentially fatal human disea Health and Human Services, Department of / National Institutes of Health 9/02/2011
THOMAS JEFFERSON UNIVERSITY $40,823 Grant Trans-NIH Recovery Act Research Support: The objectives of this supplement proposal are to understand the molecular mechanisms of prostate tumorigenesis due to deregulation of the PI3K and PTEN pathway, and to elucidate the connection of PI3K and PTEN downstream signaling components to tumor for Health and Human Services, Department of / National Institutes of Health 9/08/2011
NEW YORK INSTITUTE OF TECHNOLOGY INC $359,101 Grant Trans-NIH Recovery Act Research Support: Interventions that may stimulate or regulate healthy cardiac vessel growth are of considerable clinical relevance. Research conducted primarily on tumor growth and organ development has identified two major cellular mechanisms of angiogenesis: sprouting Health and Human Services, Department of / National Institutes of Health 1/01/2011
WAYNE STATE UNIVERSITY (INC) $367,840 Grant Trans-NIH Recovery Act Research Support: The goal of this study is to develop a systems-based intervention to increase the numbers of offers made to patients in order to increase the number of patients enrolling onto trial protocols. We will test the feasibility and efficacy of a two-component Health and Human Services, Department of / National Institutes of Health 7/17/2009
UNIVERSITY OF SOUTHERN CALIFORNIA $425,000 Grant Trans-NIH Recovery Act Research Support: The award is derived from CaliforniaG??s Mental Health Services Act to improve mental health services within the state. The specific funding is from the Southern Counties Regional Program which is comprised of four counties, Kern, Santa Barbara, San Luis Health and Human Services, Department of / National Institutes of Health 2/08/2011
4S3 BIOSCIENCE INC. $195,590 Grant Trans-NIH Recovery Act Research Support: Translational grant to develop and test a fusion protein as a potential therapeutic for Myotonic dystrophy. A second grant extension has been granted to further production efforts to generate significant drug material for testing. Health and Human Services, Department of / National Institutes of Health 6/25/2012
THE GEORGE WASHINGTON UNIVERSITY $620,379 Grant Trans-NIH Recovery Act Research Support: In Crisis Intervention Team (CIT) training, police officers participate in 40 hours of specialized training provided by local mental health professionals, family members/advocates, and mental health consumer groups. Upon completion, these officers serve a Health and Human Services, Department of / National Institutes of Health 7/21/2011
WAYNE STATE UNIVERSITY (INC) $1,044,749 Grant Trans-NIH Recovery Act Research Support: Aims of the proposal: 1) Contribute to the development and competency of pre-service STEM teachers through integration of Environmental Health-based Biotechnology lessons into an existing methods course. 2) Intergrate Environmental health science researc Health and Human Services, Department of / National Institutes of Health 9/30/2009
WAYNE STATE UNIVERSITY (INC) $490,704 Grant Trans-NIH Recovery Act Research Support: The long-term objective of our research is to augment the efficacy of the cancer treatment photodynamic thearpy (PDT). Three specific aims will test the hypothesis: 1) to demonstrate that cell killing after PDT requires a definitive, enzyme-controlled, S Health and Human Services, Department of / National Institutes of Health 7/16/2009
WAYNE STATE UNIVERSITY (INC) $418,000 Grant Trans-NIH Recovery Act Research Support: The development of breast cancer is a consequence of genetic risks and environmental exposures. Polychlorinated biphenyls (PCBs) are environmental contaminants that, despite their banned use, represent ongoing threats to human due to their persistence in Health and Human Services, Department of / National Institutes of Health 6/01/2009
WAYNE STATE UNIVERSITY (INC) $582,416 Grant Trans-NIH Recovery Act Research Support: Our general goal is to determine the temporal and spatial interactions among lipolytic proteins in adipocytes and myocytes. The goal will be accomplished by 2 specific aims: 1. To test specific mechanisms of lipase, co-activator and scaffold interactions Health and Human Services, Department of / National Institutes of Health 5/26/2009
WAYNE STATE UNIVERSITY (INC) $152,548 Grant Trans-NIH Recovery Act Research Support: This work is providing new methods and algorithms for inferring signaling pathway structures from overlapping gene sets. The latter is a new abundant data source that has not been exploited to reconstruct signaling pathways due to lack of methodological f Health and Human Services, Department of / National Institutes of Health 8/13/2011
VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY $123,928 Grant Trans-NIH Recovery Act Research Support: The Community Child Health Network (CCHN) Phase II research proposes to: (1) advance understanding of the combined biomedical, social, behavioral, and environmental influences on the course of prenatal development, pregnancy outcome, and early child deve Health and Human Services, Department of / National Institutes of Health 9/03/2009
MIRIMEDICAL, LLC $87,000 Grant Trans-NIH Recovery Act Research Support: We propose to test (in-vitro) a small surface area double fiber bundle (DFB) dialyzer, on the order of 1.6 sq m. This device will be designed for the low blood flow (<300 ml/min) and dialysate flow (<400 ml/min) markets, which include daily dialysis, noct Health and Human Services, Department of / National Institutes of Health 7/06/2010
TOTAL CHILD HEALTH, INC. $998,780 Grant Trans-NIH Recovery Act Research Support: The study's purpose is a cost-effectiveness study taking advantage of data from a large cohort derived from universal school screening for symptoms of ADHD collected by a web-based decision support system. Said system, called CHADIS, collects data from pa Health and Human Services, Department of / National Institutes of Health 9/23/2009
REGENTS OF THE UNIVERSITY OF COLORADO, THE $1,654,805 Grant Trans-NIH Recovery Act Research Support: Chronic lung diseases represent a broad spectrum of chronic fibrosing/inflammatory lung conditions that are for the most part poorly responsive to treatment and often fatal. COPD/emphysema is the fourth leading cause of death in the United States and the Health and Human Services, Department of / National Institutes of Health 11/04/2011
DREXEL UNIVERSITY $101,700 Grant Trans-NIH Recovery Act Research Support: Cocaine addicts exhibit decreased metabolic basal activity in the orbitofrontal cortex (OFC), as well as decreased metabolic responses to natural reward associated stimuli, relative to healthy controls. However, in addicts, the OFC also shows increased me Health and Human Services, Department of / National Institutes of Health 6/23/2011
ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE $17,308 Grant Trans-NIH Recovery Act Research Support: This application is submitted in response to an RFA-OD-09-004 entitled 'Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure 'Grand Opportunities' (RC2)' and addresses the NIDCR Area of Scientific Priority 'Genome-wide Stu Health and Human Services, Department of / National Institutes of Health 12/21/2011
VAXART, INC $1,246,796 Grant Trans-NIH Recovery Act Research Support: Vaxart is developing a new vaccine to prevent infection by Venezuelan Equine Encephalitis (VEE), a pathogen that can infect laboratory workers and has biowarfare potential. Because of the dangers involved with previous vaccines, we propose to develop a sa Health and Human Services, Department of / National Institutes of Health 9/12/2009
SIGA TECHNOLOGIES, INC. $1,667,535 Grant Trans-NIH Recovery Act Research Support: The family Bunyaviridae is comprised of a diverse group of viruses spread across five genera and infecting hosts from both the plant and animal kingdoms. Significant biothreats among these are several human pathogens including Rift Valley fever virus (RVF Health and Human Services, Department of / National Institutes of Health 9/01/2010
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON $68,454 Grant Trans-NIH Recovery Act Research Support: Rickettsial diseases have been a scourge of humankind throughout history. Typhus epidemics due to louse- borne Rickettsia (R.) prowazekii have caused more deaths than all the wars combined and recent epidemiological evidence documents the reemergence of e Health and Human Services, Department of / National Institutes of Health 12/02/2011
J.DAVID GLADSTONE INSTITUTES, THE $1,465,000 Grant Trans-NIH Recovery Act Research Support: 'Developing Transmissable Antivirals by Exploiting Gene-Expression Circuitry' Emerging and established viral diseases take an enormous toll on human health. Current treatment approaches are unlikely to halt epidemic spread of many viruses, notably HIV-1 Health and Human Services, Department of / National Institutes of Health 12/09/2011
UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. $86,461 Grant Trans-NIH Recovery Act Research Support: We have found that SPRY2, a key regulator of RTK to ERK signaling, is absent in about 1/3 of a small set of ovarian cancers we have investigated. We propose to test whether levels of SPRY2 predict survival of women with advanced ovarian cancer who have be Health and Human Services, Department of / National Institutes of Health 1/30/2012
NORTH CAROLINA CENTRAL UNIVERSITY $92,396 Grant Trans-NIH Recovery Act Research Support: The overall goal is to explore a two-step proteomics screen to identify genome wide metastable epialleles that may be influenced by milk thistle nutritional supplements. Health and Human Services, Department of / National Institutes of Health 9/15/2011
SCHEPENS EYE RESEARCH INSTITUTE, INC., THE $127,211 Grant Trans-NIH Recovery Act Research Support: Retinal degenerations are genetically heterogeneous disorders that affect one in every 4000 individuals and are often classified according to the type of pathology observed in rod and cone photoreceptors. Our long-term goal is to understand the transcript Health and Human Services, Department of / National Institutes of Health 11/21/2011
SRI INTERNATIONAL $461,755 Grant Trans-NIH Recovery Act Research Support: The goal of this project is to determine the role of LRRK2 mutation in the intrinsic vulnerability of nigrostriatal dopaminergic neurons and the susceptibility of this pathway to injury induced by environmental toxicants. The PI in collaboration with Dr. Health and Human Services, Department of / National Institutes of Health 8/31/2010
TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK $134,505 Grant Trans-NIH Recovery Act Research Support: Schizophrenia is a major mental disorder that affects approximately 1% of the population worldwide. Current medications significantly control symptoms of schizophrenia, but are relatively ineffective in treating underlying neurocognitive deficits or in mo Health and Human Services, Department of / National Institutes of Health 2/16/2012
UNIVERSITY OF ILLINOIS $31,657 Grant Trans-NIH Recovery Act Research Support: This proposal builds upon work suggesting that the herbal extract Scutellaria baicalensis (SbE) and its major component baicalein may simulate many important components of cardiac preconditioning (PC), i.e.trigger transient mitochondrial oxidant signaling Health and Human Services, Department of / National Institutes of Health 5/01/2009
CASE WESTERN RESERVE UNIVERSITY $265,139 Grant Trans-NIH Recovery Act Research Support: This award is for cryoelectron microscopy structural studies of complexes of a human virus with a peptide of the innate immune system with the goal of understanding the mechanism of viral neutralization. Adenovirus is a common human pathogen and engineere Health and Human Services, Department of / National Institutes of Health 6/08/2012
REGENTS OF THE UNIVERSITY OF MICHIGAN $269,263 Grant Trans-NIH Recovery Act Research Support: Bone is a complex system whose critical function is to be sufficiently stiff and strong to support the physical forces associated with daily activities. Understanding how genetic and environmental variants compromise this function is critical to fully und Health and Human Services, Department of / National Institutes of Health 1/12/2012
EMORY UNIVERSITY $240,590 Grant Trans-NIH Recovery Act Research Support: Genome-wide analysis of RXRa binding in mouse liver chromatin with ChIP-SEQ A substantial proportion of metabolic and responsive gene regulation in the liver occurs via members of the Nuclear Receptor (NR) superfamily, specifically those regulated by RXRa Health and Human Services, Department of / National Institutes of Health 11/25/2011
UNIVERSITY OF SOUTHERN CALIFORNIA $33,997 Grant Trans-NIH Recovery Act Research Support: The Baltimore Experience Corps (EC) program is a senior volunteer program designed to promote better mental and physical health in older adults through high-intensity volunteerism in public elementary schools. An ongoing trial of the Baltimore EC program Health and Human Services, Department of / National Institutes of Health 2/16/2012
REGENTS OF THE UNIVERSITY OF MICHIGAN $196,072 Grant Trans-NIH Recovery Act Research Support: The research proposed here will use archival data and multi-level/hierarchal spatial modeling to examine the geography of alcohol outlets and violence, over time, in the city of Boston. We will determine whether and how place matters in regard to the rela Health and Human Services, Department of / National Institutes of Health 3/13/2012
ST. JUDE CHILDREN'S RESEARCH HOSPITAL $242,721 Grant Trans-NIH Recovery Act Research Support: Like phosphorylation, protein ubiquitination is a reversible process to regulate essentially all cellular events. Misregulation of ubiquitination plays an important role in the pathogenesis of a variety of diseases, ranging from cancer to neurodegenerativ Health and Human Services, Department of / National Institutes of Health 3/12/2012
TUSKEGEE UNIVERSITY $1,265,489 Grant Trans-NIH Recovery Act Research Support: Bioethics Infrastructure Training Initiative Health and Human Services, Department of / National Institutes of Health 9/29/2009
UNIVERSITY OF CALIFORNIA, IRVINE $3,690,668 Contract : Normal fetal growth is a critical component of a healthy pregnancy and the long-term health of the offspring. Pivotal to understanding the dynamics of human fetal growth and to defining normal and abnormal fetal growth is the development of standards for Health and Human Services, Department of / National Institutes of Health 9/23/2010
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA $1,028,088 Grant Trans-NIH Recovery Act Research Support: Current clinical periodontal treatment is often not sufficient on its own to control destructive inflammation. This necessitates improved therapeutic approaches, especially in the elderly who are more susceptible to periodontitis. We propose that old age Health and Human Services, Department of / National Institutes of Health 1/10/2012
EAST CAROLINA UNIVERSITY $27,000 Grant Trans-NIH Recovery Act Research Support: The purpose of the current proposal was to define the importance of suppressor of cytokine signaling 3 (SOCS3) in the regulation of hepatic natural killer T cell function within the murine liver. Funding was designated to purchase a quantitative real ti Health and Human Services, Department of / National Institutes of Health 1/20/2012
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE $154,878 Grant Trans-NIH Recovery Act Research Support: Voltage-sensitive potassium (Kv) channels are proteins that exist in the membranes of all electrically excitable cell types. Kv1.4 (the mammalian homologue of Shaker) and all Kv4 (Shal-type) subunits generate potassium-selective current phenotypes design Health and Human Services, Department of / National Institutes of Health 7/16/2009
GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. $242,250 Grant Trans-NIH Recovery Act Research Support: PepT1 is mainly expressed in brush-border membranes of enterocytes in the small intestine. PepT1 has a differential pattern of expression in the small intestine. Along the vertical axis, PepT1 is most abundant at the villous tip, with expression decreasin Health and Human Services, Department of / National Institutes of Health 3/26/2012
TEXAS A&M UNIVERSITY SYSTEM,THE $219,472 Grant Trans-NIH Recovery Act Research Support: Developmental reprogramming is an important mechanism by which early life exposures to environmental agents increase susceptibility to adult disease. For xenoestrogens such as BPA, additional research is required to understand how specific estrogen recept Health and Human Services, Department of / National Institutes of Health 9/01/2009
PENNSYLVANIA STATE UNIVERSITY, THE $635,500 Grant Trans-NIH Recovery Act Research Support: The efforts of the human genome project are beginning to provide important findings for human health. Technological advances in the laboratory, particularly in characterizing human genomic variation, have created new approaches for studying the human geno Health and Human Services, Department of / National Institutes of Health 3/01/2012
EMORY UNIVERSITY $309,227 Grant Trans-NIH Recovery Act Research Support: This project G?? G??Performance Indices of Social Disability in Toddlers with AutismG?? G?? addresses Challenge AreaG??(04) Clinical ResearchG?? and Specific Challenge Topic G??Autism: Addressing the Challenge (04-MH-101*)G??; and Challenge Area G??(01) B Health and Human Services, Department of / National Institutes of Health 2/14/2012
CATHOLIC HEALTHCARE WEST $100,000 Grant Trans-NIH Recovery Act Research Support: The overall goal of the proposed study is to validate specific biomarkers for amyotrophic lateral sclerosis (ALS). ALS is a fatal motor neuron degenerative disease that can strike adults of any age, yet we know little about its causes and cannot rapidly d Health and Human Services, Department of / National Institutes of Health 9/16/2011
UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. $381,399 Grant Trans-NIH Recovery Act Research Support: Tumor-initiating cells, or cancer stem cells (CSC), are a small subpopulation of cells capable of self-renewal and differentiation, which are highly resistant to chemo/radiation therapy and may be responsible for tumor recurrence and metastasis. The tumo Health and Human Services, Department of / National Institutes of Health 3/04/2011
EMORY UNIVERSITY $292,030 Grant Trans-NIH Recovery Act Research Support: Genetics of Hypertension Risk Factors and Sequela in African Americans Health and Human Services, Department of / National Institutes of Health 8/10/2011
JAMES' ELECTRICAL CONTROL, INC. $638,141 Contract : Telecommunication Installation Health and Human Services, Department of / National Institutes of Health 6/07/2010
UNIVERSITY OF WISCONSIN SYSTEM $88,478 Grant Trans-NIH Recovery Act Research Support: Chronic kidney disease (CKD) affects an estimated 19 million adults in the US and is associated with a higher risk of cardiovascular disease (CVD) and mortality. This increased risk is partially explained by an elevated prevalence of several CVD risk fac Health and Human Services, Department of / National Institutes of Health 4/24/2012
TUFTS MEDICAL CENTER, INC. $29,184 Grant Trans-NIH Recovery Act Research Support: Same as Description of Jobs Created - Dr. Levey's participation in designing analyses, delegating writing assignments, and critical review of draft manuscripts will accelerate publication of results from this unique clinical population. Health and Human Services, Department of / National Institutes of Health 4/26/2012
TRUSTEES OF TUFTS COLLEGE INC $1,921,419 Grant Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Breast cancer incidence has increased substantially during the last three decades, coinciding with the introduction of hormone mimics into the environment. It has been postulated that developmental exposure to xenoestr Health and Human Services, Department of / National Institutes of Health 9/27/2009
REGENTS OF THE UNIVERSITY OF MICHIGAN $248,087 Grant Trans-NIH Recovery Act Research Support: All 19-carbon androgens derive from 21-carbon steroids via sequential 17-hydroxylase and 17,20-lyase activities of cytochrome P450c17 (CYP17A1). The complex chemistry of the 17,20-lyase reaction is selectively stimulated up to 10-fold by cytochrome b5 (b5 Health and Human Services, Department of / National Institutes of Health 6/13/2012
UNIVERSITY OF FLORIDA $805,869 Grant Trans-NIH Recovery Act Research Support: The public health impact of the HealthStreet approach to recruit more underrepresented populations into research and link them to needed services is significant. When samples enrolled for research studies are comprised of diverse populations, there is gre Health and Human Services, Department of / National Institutes of Health 4/26/2012
ARIZONA STATE UNIVERSITY $336,943 Contract : RECOVERY:Computational Thinking to Support Clinicians and Biomedical Scientists. Text mining of clinical narratives: porting semi-supervised concept and relationship extraction techniques from biomedical literature mining. Health and Human Services, Department of / National Institutes of Health 9/21/2010
NEW YORK UNIVERSITY (INC) $72,813 Grant Trans-NIH Recovery Act Research Support: NOREPINEPHRINE TRANSPORTER IMAGING IN ALCOHOL DEPENDENCE AND OBESITY (8 OF 14) Health and Human Services, Department of / National Institutes of Health 4/05/2012
TUSKEGEE UNIVERSITY $1,265,489 Grant Trans-NIH Recovery Act Research Support: Bioethics Infrastructure Training Initiative Health and Human Services, Department of / National Institutes of Health 9/29/2009
PURDUE UNIVERSITY $223,084 Grant Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06): Enabling Technologies and specific Challenge Topic, 06-DC-101: Develop Improved Hearing Devices. It is projected that by 2030 there will be over 40 million adults and over 2 million children with heari Health and Human Services, Department of / National Institutes of Health 9/30/2009