Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $39,809 | Grant | Trans-NIH Recovery Act Research Support: Meiosis is a specialized cell division process that results in the formation of haploid gametes (i.e.: eggs and sperm) and is therefore essential for sexual reproduction and generating genetic diversity. The reduction of the chromosome complement by half | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| TUFTS MEDICAL CENTER | $53,600 | Grant | Trans-NIH Recovery Act Research Support: Chronic kidney disease (CKD) is an important global public health problem and may affect upto 13% of the population of the United States. CKD leads to dialysis and premature cardiovascular death. Inherited factors are responsible for increased risk of dis | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| NEW YORK UNIVERSITY (INC) | $463,840 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We request funds to purchase the Vevo 2100 high resolution ultrasound imaging system from Visualsonics. Biomedical imaging has emerged as an essential tool in the phenotypic analysis of experimental animal model system | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $92,677 | Grant | Trans-NIH Recovery Act Research Support: This supplement is expected to accelerate the pace of our research by increasing our rate of participant recruitment, enabling us to reach the sample numbers necessary for the proposed genetic studies sooner. NCE has been awarded for the period 01/01/201 | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Mitochondria are membrane-bound organelle found in animal and plant cells, providing the power source for cellular activities. Disorders of mitochondrial function lead to a number of diseases, such as obesity and diabetes. Reversible modification of prote | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF WASHINGTON | $79,132 | Grant | Trans-NIH Recovery Act Research Support: This project is to determine how the intracellular metabolite cyclic diguanylate (c-di-GMP) stimulates bacterial biofilm formation. Our focus is on the opportunistic pathogen and model biofilm bacterium, Pseudomonas aeruginosa. Biofilms, defined as surfac | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: We propose here to focus on the parent Grant Specific Aim obtaining broader, ?genome-wide? insight into the three dimensional regulation of nuclear architecture. Specifically, we are in a position to explore new approaches to several unexpected aspects of | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF CHICAGO, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Towards the physiologic function of MiRP-3. The research: Potassium channels catalyze the movement of K+ ions across the cell membrane, and their function is essential for cellular electrical activity and electrolyte homeostasis. Many K+ channels are regu | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $167,784 | Grant | Trans-NIH Recovery Act Research Support: The NGA and account for this grant only were obtained in the second half of March, although the official start date was March 1, 2010, this was a retroactive date. Spending and work is commencing now. | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Biological research is at the cusp of a technological revolution of the type that has repeatedly transformed research in recent decades. With the arrival of next-generation DNA sequencers, individual laboratories are able to ask questions that just five y | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF MASSACHUSETTS | $5,237,334 | Grant | Trans-NIH Recovery Act Research Support: Responding to RFA-RR-09-007, this application seeks funding to renovate portions of the 6th, 7th, 8th floors, and roof level of the University of Massachusetts Medical Schools (UMMS) research wing. The renovation plan will consolidate, enlarge, and enhan | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| BAYLOR COLLEGE OF MEDICINE | $88,510 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In animals, cells undergoing apoptosis and necrosis are rapidly internalized by other cells via phagocytosis (engulfment) and degraded inside phagocytes. The removal of these dying cells provides a safe means for elimi | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| EMORY UNIVERSITY | $49,945 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement application encompasses activities of the Emory Epithelial Pathobiology Research Development Center and is aimed at updating a critical component of the Morphology and Image Analysis Core (Core B). Research supported by the | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| RANGER GROUP LLC, THE | $4,918,839 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 13N | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $499,512 | Grant | Trans-NIH Recovery Act Research Support: High Performance Computing Cluster for Bioimaging and Computational Biology. To add 1,400 processor cores to the existing shared computing cluster at California Institute for Quantitative Biosciences (QB3) at University of California, San Francisco. The u | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| NORTHWESTERN UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Abstract Human allogeneic islet cell transplantation as a therapy for cure for type 1 diabetes can be significantly improved if the deleterious effects of indefinite immunosuppression, particularly with their direct toxicity to cells, can be eliminated. T | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $4,380,000 | Grant | Trans-NIH Recovery Act Research Support: Oregon Health & Science University (OHSU) is requesting funds to renovate 5,431 gross square feet of core facilities space that will integrate two important research areas: flow cytometry and genomic analysis. The goal of this initiative is to improve fac | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF MIAMI | $145,474 | Grant | Trans-NIH Recovery Act Research Support: Funds provided under this grant have been used to develop and characterize a new technology of Open Reading Frame (ORF) Phage Display to identify Autoantigens in patients with Uveitis. The specific Aim is to identify autoantigens by ORF phage display and | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF MISSOURI SYSTEM | $450,000 | Grant | Trans-NIH Recovery Act Research Support: The scientific objective of this proposal is to develop judiciously designed novel monomers, which when formulated into a dental adhesive, will drastically improve the adhesive/dentin bonding, thus significantly extending the longevity of resin-based toot | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $242,589 | Grant | Trans-NIH Recovery Act Research Support: A classical view claims that oxytocin (OT) fosters affiliative behaviors and arginine vasopressin (VP) enhances aggression. But a lot of data conflict with this. The confusion is not due purely to neuroanatomical details, or gender or species. I will use | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $72,743 | Grant | Trans-NIH Recovery Act Research Support: Mechanistic Studies of Nucleic Acid Damage and Their Application. The long term goal of this research is to understand how nucleic acids are oxidatively damaged, and to use this knowledge to design new therapeutic candidates and biotechnology tools. Nucle | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Retinoic acid (RA), the biologically active form of Vitamin A, is essential for a variety of biological processes. RA binds to nuclear receptors, retinoic acid receptor (RAR) and retinoid receptor X (RXR), to regulate target gene expression by triggering | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| EMORY UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Project Summary (Abstract) This application addresses broad Challenge Area (14) Stem Cells, and meets a few specific Challenge Topics: 14-EB-101: Synthetic Delivery Systems for Generating Pluripotent Stem Cells 14-DK-101: Induced pluripotent stem cells G? | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant is to define the role of Erythroid Krupple-Like Factor (EKLF) in globin gene switching during development. We have deleted the 50 bp upstream enhancer of the EKLF gene in ES cells and demonstrated that fetal globin ge | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| UNIVERSITY OF WASHINGTON | $217,113 | Grant | Trans-NIH Recovery Act Research Support: The number of NIH-funded research grants and projects using imaging technology is steadily increasing at the University of Washington (UW). The Department of Radiology has installed dedicated high-end research scanners (e.g., 3T MRI, PET-CT, microPET, et | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $347,946 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests funds to purchase a new CyAn ADP 9 color Flow Cytometry Analyzer for the Center for Tropical and Emerging Global Disease/University of Georgia Flow Cytometry Core Facility. Although housed within and operated and maintained by the U | Health and Human Services, Department of / National Institutes of Health | 2/15/2010 |
| TRUSTEES OF BOSTON UNIVERSITY | $103,704 | Grant | Trans-NIH Recovery Act Research Support: This supplement seeks to deploy and use new analytical techniques to study the role of brain biometals in Alzheimer's disease. The supplement will deploy new technology that was not available at the time the parent grant was submitted to address and expan | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $99,875 | Grant | Trans-NIH Recovery Act Research Support: This award is for equipment to purchase feeding cages, BioTek Synergy MX plate reader and Column Screening Kit. These equipment are requested for mouse phenotyping. | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| TEXAS AGRILIFE RESEARCH | $243,050 | Grant | Trans-NIH Recovery Act Research Support: Abnormal energy regulation may contribute to onset and progression of chronic metabolic conditions such as obesity, diabetes mellitus, cardiovascular disease, and cancer, which cause approximately 60% of the world's mortality [rev. in (1). Our lab is inte | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| THE WASHINGTON UNIVERSITY | $42,045 | Grant | Trans-NIH Recovery Act Research Support: Both types 1 and 2 diabetes (T1DM, T2DM) result from the inability of beta cells to secrete sufficient insulin to maintain normal glucose homeostasis due to an acquired secretory defect and/or inadequate beta cell mass. Mammalian target of rapamycin (mTOR | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $170,150 | Grant | Trans-NIH Recovery Act Research Support: Translation initiation is a crucial point of regulation of eukaryotic gene expression. In response to a variety of environmental insults, cells down-regulate the primary (cap-dependent) mechanism of translation while favoring expression of a select group | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $2,040,641 | Grant | Trans-NIH Recovery Act Research Support: This G20 proposal from the University of Virginia School of Medicine (UVA SOM) requests $2.1 M to upgrade and consolidate the UVA SOM electron microscopy (EM) resources into a Molecular Electron Microscopy Core (MEMC) facility. We estimate that the associ | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $121,557 | Grant | Trans-NIH Recovery Act Research Support: The lens has an internal circulation that is generated by ion transport, which creates fluid movement in the same pattern. The circulation of ions depends on fiber cell gap junctions to conduct intracellular, outwardly directed fluxes of Na2+ and Ca2+, wh | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $65,000 | Grant | Trans-NIH Recovery Act Research Support: We are requesting supplemental funding to purchase equipment that will help us achieve the objectives of the above project. The specific aims for the current funding period are: (1) to prepare highly functionalized three-member ring silicon compounds and | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $4,115,581 | Grant | National Center for Research Resources, Recovery Act Construction Support: Funding is to support construction of a new state-of-the-art vivarium at UC Santa Cruz, which will support NIH-funded research involving vertebrate animals. The new vivarium will replace a 25-year old facility that lacks crititical features necessary for mo... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| VALA SCIENCES INC. | $94,761 | Grant | Trans-NIH Recovery Act Research Support: These funds were awarded to Vala Sciences Inc (VSI) as a Recovery Act Administrative Supplement to grant 3R41DK082087 Automated quantification of lipid droplets in fatty liver tissue sections. The purpose of the supplement is to fund the purchase of an | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| WASHINGTON UNIVERSITY, THE | $30,000 | Grant | Trans-NIH Recovery Act Research Support: Osteoporosis and its associated fractures are a major health problem in the USA today. Risk of osteoporotic fractures is affected by gender, age, family history, and obesity with females being at higher risk than males, older individuals at higher risk th | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| GEORGETOWN UNIVERSITY (THE) | $78,514 | Grant | Trans-NIH Recovery Act Research Support: This project examines the cellular mechanisms that promote initiation of DNA synthesis li DNA recombination. Such processes playa vital role in genetic exchange, double-strand break repair, and restart of replication forks. Bacteriophage Mu replicates its | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| DUKE UNIVERSITY | $37,871 | Grant | Trans-NIH Recovery Act Research Support: The broad long-range goals of this project are to understand how two major classes of chemotherapeutic agents cause DNA damage and how cells deal with DNA-protein crosslinks which are induced by these agents. The repair of DNA-protein crosslinks is very p | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $99,870 | Grant | Trans-NIH Recovery Act Research Support: We have made excellent progress with the parent grant project, elucidating the identity of Mtm pathway core components that regulate and respond to specific phosphoinositides important for cellular remodeling in vivo. Our ongoing research continues to pur | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| WILLIAM MARSH RICE UNIVERSITY | $99,869 | Grant | Trans-NIH Recovery Act Research Support: MedMyst III will create web-based games to effectively engage middle school students in science and present current NIAID-funded research on infectious diseases. The excitement of doing science and the variety of science career opportunities will be key e | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF CENTRAL FLORIDA | $434,812 | Grant | Trans-NIH Recovery Act Research Support: This study will test a prototype for a game that builds the skills that Latinas need to resist pressure to engage in intercourse when they are in middle school, thereby decreasing their risk for teen pregnancy and sexually transmitted infections. Study re | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| LUCEOME BIOTECHNOLOGIES, L.L.C. | $45,000 | Grant | Trans-NIH Recovery Act Research Support: More than 500 different protein kinases have been identified in humans and represent 1.7% of the human genome. Protein kinases function by catalyzing the transfer of the γ-phosphoryl group of ATP to the hydroxyl group on a specific protein substrate. | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| THE VANDERBILT UNIVERSITY | $493,128 | Grant | Trans-NIH Recovery Act Research Support: Voltage-gated sodium channels are heteromultimeric integral membrane proteins that are responsible for the initial phase of the action potential in most excitable cells. A variety of inherited disorders affecting skeletal muscle contraction (hyperkalemic | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| MONELL CHEMICAL SENSES CENTER | $99,744 | Grant | Trans-NIH Recovery Act Research Support: This is an award to purchase a LabMaster Fluid Intake Recording System in order to accelerate the tempo of research in NIH R01 project DK-46791 Physiology of calcium appetite. A crucial component of this project is the measurement of calcium consumption | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF WASHINGTON | $115,000 | Grant | Trans-NIH Recovery Act Research Support: It is essential to develop surface analysis techniques capable of providing quantitative and detailed surface chemical state information at high spatial resolutions, both for 2-D imaging of surfaces and 3-D imaging of the near surface region. Until recen | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| UNIVERSITY OF CHICAGO, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this revised proposal is to elucidate the molecular mechanisms coupling electrical excitability of -cells to glucose-induced insulin secretion (GSIS) in normal and diabetic states. We seek to test hypotheses concerning the role of | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF MARYLAND | $7,329,060 | Grant | Trans-NIH Recovery Act Research Support: The University of Maryland School of Medicine (UMSOM) proposes to renovate 27,000 gross square feet of lab, office, and conference space on the sixth and seventh floors of the Frank C. Bressler Research Building (BRB). The proposed renovation project will | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,683 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The goal of this proposal, entitled Identity, regulation, and function of mTOR phosphorylation sites, is to understand the mechanisms by which mTOR, the mammalian target of rapamycin, is regulated by physiological sign | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $495,100 | Grant | Trans-NIH Recovery Act Research Support: To purchase a high-speed fluorescence-activated Cell Sorter, FACSAria II by Becton Dickinson. This instrument will support research in a wide range of research fields e.g. Transplantation, Diabetes, Asthma, Cancer & Immunology | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $889,321 | Grant | Trans-NIH Recovery Act Research Support: This project aims to apply the discovery that an immune molecule, tumor necrosis factor (TNF), changes the excitability of neurons to the transmitter glutamate, increasing cell death after spinal cord injury. Drugs that block TNF will be used to reduce se | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| NORTHWESTERN UNIVERSITY | $33,323 | Grant | Trans-NIH Recovery Act Research Support: Dendritic cells (DCs) are potent antigen presenting cells (APCs) due to the ability to stimulate nai've T cells with antigen. DCs are also a promising new source of vaccine development. Endocytosis and migration are two key processes in the ability of DCs | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Structure and dynamics of membrane microdomains used for viral entry and egress In this administrative supplement , we proposed to accelerate the progress on our parent grant (NIH GM 41402) in which we seek to quantitatively define the manner in which th | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| DUKE UNIVERSITY | $100,001 | Grant | Trans-NIH Recovery Act Research Support: Human red blood cell (erythrocyte) diseases, including anemia and malaria, pose a huge burden for the human race. Our understanding of these diseases is rather limited. For example, while the genetic cause of sickle cell diseases (SCD) and the positive se | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $27,000 | Grant | Trans-NIH Recovery Act Research Support: The study of glycosaminoglycan (GAG) degrading enzymes such as heparinases chondroitinases exolytic D4 5-glycuronidase and sulfatases require significant of purified enzymes. These enzymes can be extracted from natural sources or can be produced by re | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| YALE UNIVERSITY | $48,639 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to understand lymphoid organ development and function in ontogeny and inflammation. Accordingly, the parent grant has 4 specific aims: 1. Determine how HEVs and LVs are regulated in acute inflammation 2. Determine how HEVs an | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| DELOITTE CONSULTING LLP | $800,000 | Contract | : The purpose of this award is to acquire professional Information Technology (IT) services to provide development and operations for NIH nVision and NIH Data Warehouse project to support the NIH community ES-21 NBIS-NBS/eRA Integration Project using the Am | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| THE WASHINGTON UNIVERSITY | $98,230 | Grant | Trans-NIH Recovery Act Research Support: Our hypothesis in the previous project period was that a pancreatic islet Ca2+-independent phospholipase A2 (iPLA2 beta) is activated upon stimulation with secretagogues and that its products participate in p-cell signaling. We have now cloned iPLA2 beta | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $120,000 | Grant | Trans-NIH Recovery Act Research Support: Rhizobium-legume symbioses involve processes that are fundamental to all bacterial-host interactions. These include (a.) prokaryotic-eukaryotic recognition, (b.) interaction with the host defense mechanism, and (c.) bacterial and host differentiation proc | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF MASSACHUSETTS | $124,975 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award is an administrative supplement to NIH Grant R01 GM081422. The stated goals of the supplement request were two-fold. First, we proposed to develop a new high-throughput sequencing / in vitro selection method in order to increase our capa | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $1,279,174 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application addressed broad Challenge Area (05) Comparative Effectiveness Research and specific Challenge Topic 05-MD-102*: Prevention of Chronic Diseases in Disparity Populations. The prevalence of pediatric obes | Health and Human Services, Department of / National Institutes of Health | 2/23/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $143,500 | Grant | Trans-NIH Recovery Act Research Support: Cholestatic liver diseases are among the most important liver disorders that occur in infants and children, leading to devastating morbidity and accounting for over 70% of liver transplants performed during childhood, posing a major public health burden. | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $81,246 | Grant | Trans-NIH Recovery Act Research Support: How does the facial skeleton acquire its characteristic shape? What is the developmental basis of craniofacial birth defects in humans? The long-term goal of this proposal is to understand how epithelia communicate with skeletal precursors to generate pre | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| MONTANA STATE UNIVERSITY, INC | $14,896,564 | Grant | National Center for Research Resources, Recovery Act Construction Support: This project involves demolition of outdated lab space and new construction within an existing building to update and improve the quality of the space. Renovation of approximately 37,000 square feet will allow for reconfiguratation of space to create themat... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $85,851 | Grant | Trans-NIH Recovery Act Research Support: To ensure cell survival and maintain genomic integrity, chromosomes must be equally distributed to daughter cells during mitosis. The kinetochore is a specialized region of the chromosome that binds microtubules of the mitotic spindle. All eukaryotes use | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| CAPINTEC INC | $193,750 | Contract | : Dual Hot Cell Equipment (Analytical Laboratory Instrument Manufacturing) | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ILLINOIS | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Autism, neuropeptide hormones and potential pathway genes: Supplementary funds will be utilized to (a) measure the closely related, arginine vasopressin (AVP) levels as an intermediate phenotype for the examining AVP pathway genes in autism, and (b) enabl | Health and Human Services, Department of / National Institutes of Health | 3/01/2010 |
| EMORY UNIVERSITY | $101,600 | Grant | Trans-NIH Recovery Act Research Support: 1. Purchase equipment to aid in purification of flagellin and analysis of TLR5-deficient mice. 2. Utilize a commercial provider to generate TLR5 in a gnotobiotic state. This will generate employment opportunities at Taconic, Inc (Taconic, NY). The mice ha | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The recent research from this laboratory provides direct evidencethat Drosophila is a suitable genetic model for studying molecular, cellular and neural basis of feeding behavioral control and eating disorders. We have shown that Drosophila neuropeptide F | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $62,718 | Grant | Trans-NIH Recovery Act Research Support: The funds will be used to purchase equipment. 1) General Electric ATKA Protien Purification System 2) Becman-Coulter 45 Ti Ultracentrifuge Rotor and 3)VWR-International Refrigerated Desk-top Centrifuge #97009-874. This equipment supplement will help with | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $107,673 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to determine the catalytic mechanism of the glmS ribozyme, which is an important RNA enzyme that regulates bacterial metabolism. The approach is to use 8-azapurine fluorescence to monitor the protonation states of G33, an essen | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $910,730 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this application is to find out which non-protein-coding RNAs are differentially expressed in Alzheimer's disease patients. We will create an inventory of nonprotein-coding RNAs by performing extensive sequencing of RNA samples fr | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This application for an administrative supplement proposes to accelerate the tempo of the research efforts of the currently funded grant (K23-MH071374) by providing addition support for data collection and data analysis. Funds from the administrative sup | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| CORNELL UNIVERSITY, INC | $51,061 | Grant | Trans-NIH Recovery Act Research Support: Chronic inflammation observed in obesity has been implicated in the development of medically important complications, particularly atherosclerosis, cancer, insulin resistance and non-alcoholic fatty liver disease. Macrophages, key mediators of inflammatio | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER | $9,711,810 | Grant | National Center for Research Resources, Recovery Act Construction Support: The goal of the proposed research construction project is to provide an optimal environment at Los Angeles Biomedical Research Institute (LA BioMed) in which to conduct collaborative, interdiscliplinary, translational researchch in chronic diseases. We prop... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $181,879 | Grant | Trans-NIH Recovery Act Research Support: Irritable bowel syndrome (IBS) is a chronic, prevalent, often disabling, GI disorder for which there is no reliable and satisfactory medical option for its full range of symptoms (abdominal pain, bowel dysfunction). An accumulating body of evidence indica | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $227,250 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of our studies is to identify the +?-cell biochemical, molecular and functional events that underlie this adaptation. Our laboratory has taken the approach of studying rodents with successful +?-cell adaptation to a lowered +?-cell mass o | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH | $235,000 | Grant | Trans-NIH Recovery Act Research Support: These funds will be used to purchase an nCounter G?? system from NanoString Technologies. The nCounter system is a new approach to gene expression analysis that offers the data quality of Real-Time PCR with higher multiplexing, better throughput and lower | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $27,936 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this research program is to develop an integrated mechanistic view of how organisms coordinate the actions of their replication machinery with those of other cellular factors involved in DNA repair and damage tolerance. Failure to do | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| CARNEGIE MELLON UNIVERSITY | $99,865 | Grant | Trans-NIH Recovery Act Research Support: The transition from adolescence to early adulthood is a neglected area of research, despite the high prevalence of risk behaviors that emerge and the potential for these risk behaviors to set in motion a pattern of behavior that will persist throughout ad | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $42,950 | Grant | Trans-NIH Recovery Act Research Support: The parent grant for this supplement aims to identify the genetic determinants of nutrient intake and spontaneous physical activity, behaviors fundamental to the development of obesity phenotypes. This research project has reached the stage of dissecting | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| UNIVERSITY OF ARIZONA | $135,000 | Grant | Trans-NIH Recovery Act Research Support: We request funds to purchase an automated crystallization system composed of an automatic liquid dispensing unit for screening crystallization conditions, a digital microscope camera stage for monitoring the crystallization experiments, and two temperatur | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $154,941 | Grant | Trans-NIH Recovery Act Research Support: Our proposed studies over tthe funding period of this ARRA Supplement Award will provide a more detailed understanding of how Daam1 regulates gastrulation and neural tube closure which is the major aim of our parental RO1 grant and an area of study that r | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| JOSLIN DIABETES CENTER, INC. | $42,201 | Grant | Trans-NIH Recovery Act Research Support: Mediators and Modifiers of NF-kB in Insulin Resistance - The parent grant looks at tissue-specific effects of obesity on NF-kB, first in classical tissues such as fat, liver and muscle, and more recently in leukocytes, systemically and in these same tissu | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| INDIVUMED INC. | $1,337,078 | Contract | : Indivumed has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas project. Specifically this award is to fund the provision of 550 colon/colorectal, 140 breast, 75 lung, 90 gastric and 80 prostate and 11 bladder cancer | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $495,988 | Grant | Trans-NIH Recovery Act Research Support: This is a Shared Instrumentation Grant Application for a new 120kV basic transmission electron microscope (TEM) to be used at the Academic Health Center of the University of Minnesota. The primary purposes of this request are to replace obsolete TEMs, con | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| BUSINESS SERVICE MANAGEMENT, INC. | $8,148 | Contract | : Toshiba 1600EP Series 6.0kVA Uninterruptible Power System | Health and Human Services, Department of / National Institutes of Health | 11/13/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $220,002 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to increase knowledge on autophagy-mediated mechanisms pertaining to metabolic diseases such as diabetes, obesity, and insulin resistance. Autophagy is an evolutionarily-conserved cellular process through which eukaryotic cells diges | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $96,011 | Grant | Trans-NIH Recovery Act Research Support: Proper salivary gland function is critical for the maintenance of oral health and physiological well-being. Saliva functions to moisten the oral tissues as an aid for speech, as a solvent important for taste, and as a masticatory wetting agent/lubricant i | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $99,801 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplemental application is to examine the regulation of expression and role of Pax6 isoforms during RA-dependent differentiation of wild type P19 and P19 AS-2 cells (lack expression of PBX proteins) to neuronal cells. Specifically we wi | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| DANA-FARBER CANCER INSTITUTE, INC. | $82,284 | Grant | Trans-NIH Recovery Act Research Support: Estrogen plays multiple roles in normal physiology and a pathologic one in breast cancer. The completion of the sequencing of the human genome has allowed the near-complete identification of the expressed regions of protein-coding genes, however, little i | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $14,179,569 | Grant | National Center for Research Resources, Recovery Act Construction Support: This application seeks funds for the construction of the first Animal Biosafety Level 3 Laboratory (A-BSL-3) in the Division of Laboratory Animal Research at the Health Sciences Center at Stony Brook University. The A- BSL-3 w will have three suites for wor... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $2,198,020 | Grant | Trans-NIH Recovery Act Research Support: The Falk Cardiovascular Research Center, founded by Norman Shumway, is the core translational research facility of the Stanford Cardiovascular Institute (CVI), Department of Cardiothoracic Surgery, and Division of Cardiovascular Medicine. The requested in | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $118,804 | Grant | Trans-NIH Recovery Act Research Support: Wound repair is a basic and crucial property of all tissues including the cornea. Because of its exposed position at the surface of the eye, the cornea is at risk to a variety of wounds including those created during laser surgery to correct vision. Our | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $168,377 | Grant | Trans-NIH Recovery Act Research Support: This instrumentation will significantly improve the research capacity and productivity of a large number of NIH-supported investigators via an institutionally supported, well-established core facility. The system will allow high-throughput quantitation of | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| LOYOLA UNIVERSITY | $2,701,560 | Grant | Trans-NIH Recovery Act Research Support: This award will support the design, construction and fixed equipment purchases required to expand our IT capacity by establishing a new computer facility that will be designated solely for research needs. The proposed renovations will create a research co | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $166,924 | Grant | Trans-NIH Recovery Act Research Support: Enveloped viruses must fuse viral and cellular membranes to transfer the viral nucleic acid into the host cell and initiate the infectious cycle. These viruses have evolved dedicated fusion proteins that catalyze this energetically unfavorable process. Th | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF LOUISVILLE | $96,950 | Grant | Trans-NIH Recovery Act Research Support: The award will pay salary to perform the following research study: Our lab developed a direct fluorescence assay with injected albumin to examine the perfusion of individual nephrons microscopically. To go beyond the limitations of morphological analysi | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $149,966 | Grant | Trans-NIH Recovery Act Research Support: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are important causes of chronic liver disease in the United States. The NASH Clinical Research Network (NASH CRN) was established in 2002 to conduct research related to its c | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $150,899 | Grant | Trans-NIH Recovery Act Research Support: The central hypothesis of the parent project (R01 DK055524-11A2) is that heterotrimeric G proteins and arrestins function as independent G protein-coupled receptor (GPCR) signal transducers that mediate distinct facets of the cellular response to GPCR sti | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH | $184,121 | Grant | Trans-NIH Recovery Act Research Support: Amyloids are implicated in many deadly human diseases from systematic amyloidosis to Alzheimer's Disease. These diseases are responsible for large social and financial costs. Gaining a greater understanding of amyloid structures and the forces that govern | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $83,989 | Grant | Trans-NIH Recovery Act Research Support: Fibrous connective tissue provides mechanical support and frameworks for the other tissues of the body. Type 1 collagen is the major protein component of fibrous connective tissue. Fibroblasts are the cell type primarily responsible for collagen biosynthe | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| UNIVERSITY OF CHICAGO, THE | $194,392 | Grant | Trans-NIH Recovery Act Research Support: Schizophrenia affects about 1.3% of the population and yet is responsible for US$28 billion in annual health care costs. The burden of schizophrenia to the patients, their family members and to the society is large. Antipsychotic drugs are the first line | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| BAYLOR COLLEGE OF MEDICINE | $12,232 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Type 1 diabetes mellitus (T1DM) is currently managed using modulation of dietary carbohydrates and insulin. Paradoxical post-meal hyperglucagonemia is associated with post-prandial hyperglycemia in T1DM. Glucagon suppr | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| THE VANDERBILT UNIVERSITY | $175,427 | Grant | Trans-NIH Recovery Act Research Support: Exciting and unanticipated new results from Aim 3.3 of our currently funded grant RO1 grant GM52948, raising the question of whether the human DNA helicase B under investigation in Aim 3 may be the long-sought vertebrate ortholog of S. cerevisiae Sld3. T | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $149,163 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to develop an additional training component to introduce UC Irvine Bridges to Baccalaureate Program participants to biomedical research, by engaging them in an original experimental research. This novel training and rese | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $140,000 | Grant | Trans-NIH Recovery Act Research Support: Cells dispatch a variety of critical functions via cytoskeletal arrays that are inherently transitory, i.e. structures that assemble in response to specific cues, perform their task, and then disassemble within the space of several minutes. In the propose | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| WAYNE STATE UNIVERSITY (INC) | $894,493 | Grant | Trans-NIH Recovery Act Research Support: The aim of our study is to compare the effectiveness of three complementary and alternative medicine therapies in reducing the level of stress and anxiety in pediatric patients, ages 1-12 years, undergoing sedation for imaging studies and importantly redu | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| SYSTEMS RESEARCH AND APPLICATIONS CORPORATION | $544,995 | Contract | : The purpose of this award is to support required IT System Enhancements for the NIEHS Division of Extramural Research and Training (DERT) Granting activities following an analysis of expansion requirements New systems are to be configured and deployed wi | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $499,961 | Grant | Trans-NIH Recovery Act Research Support: These ARRA funds will be used to purchase a special order configuration of the Becton Dickinson (BD) LSR II Flow Cytometer. This configuration of the BD LSR II has five lasers; (Blue laser/Red laser/Yellow-Green laser/Violet laser/UV laser) and the BD Hig | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| CELLOMICS, INC. | $227,856 | Contract | : **Recovery Order** Array Scan VTI HCS Reader Bundle & Accessories | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $498,111 | Grant | Trans-NIH Recovery Act Research Support: We propose to upgrade the siRNA Screening System at the High-Throughput Bioscience Center (HTBC), a core facility that supports high-throughput (HT) research at Stanford University. Genomic-scale siRNA (small interfering RNA) screening with HT imaging has | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $102,023 | Grant | Trans-NIH Recovery Act Research Support: The long-range objective of this proposal is to gain insight into the mechanism of heparan sulfate proteoglycan assembly and its regulation. Heparan sulfate proteoglycans participate in a variety of physiological processes by binding, activation or immobi | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| TUFTS MEDICAL CENTER PARENT, INC. | $307,552 | Grant | Trans-NIH Recovery Act Research Support: Epidemiological studies have found less skin cancer in people who have high levels of constitutive pigment and/or tan well. However, we have incomplete understanding of other factors involved in the development of skin cancer, such as capacity to repair p | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF MASSACHUSETTS | $88,765 | Grant | Trans-NIH Recovery Act Research Support: TGFp superfamily growth factors, including activins, myostatin, and bone morphogenetic proteins (BMPs), have numerous roles in development and adults and are often dysregulated in diseases ranging from cancer to infertility. Activin and myostatin are regu | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $86,095 | Grant | Trans-NIH Recovery Act Research Support: ): Pancreatic beta-cell growth and function adapt to changing physiologic demands of the host, but the mechanisms regulating these facultative responses remain unclear. Inadequate adaptation leads to beta-cell failure, and can promote pathogenesis of diab | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $57,270 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to Notice Number (NOT-OD-09-056) / Notice Title: NIH Announces the Availability of Recovery Act Funds for Administrative Supplement Applications. This administrative supplement will expand the depth and increase the tempo of t | Health and Human Services, Department of / National Institutes of Health | 2/22/2010 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $412,500 | Grant | Trans-NIH Recovery Act Research Support: Alcohol abuse and consumption are major causes of liver disease and is a major health problem in the United States. However, the pathogenesis of alcoholic liver diseases (ALD) is not completely known although recent research suggests that apoptosis is inv | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $99,927 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the administrative supplement is to test the hypothesis that type 2 Ucns and CRF2 receptors are part of the integrated homeostatic system that normally regulates energy balance to oppose excess weight gain. To expedite this project, | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $33,690 | Grant | Trans-NIH Recovery Act Research Support: The Study to Help the AIDS Research Effort (SHARE) was funded by NIAID and NCI in 1983 to study the natural history of infection with human immunodeficiency virus, type 1 (HIV). SHARE, along with similar sites in Chicago, Pittsburgh, and Los Angeles, form | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| NORTHWESTERN UNIVERSITY | $309,000 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this proposal is to address the A2ALL Funding Opportunity Announcement objective to improve understanding of long-term health and well-being of living donors and on the efficacy of living donor liver transplantation (LDLT). Primary | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $5,846 | Grant | Trans-NIH Recovery Act Research Support: Mutations in TRPC6, a nonspecific cation channel, have been found to lead to hereditary forms of focal segmental glomerulosclerosis. This project aims to define the role of TRPC6 in normal and abnormal glomerular function, with the goal of identifying the | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $171,706 | Grant | Trans-NIH Recovery Act Research Support: The obesity epidemic in the U.S. continues unabated, and is accompanied by substantial complications, including diabetes, cardiovascular disease, and death. Obesity is strongly influenced by sequence variation in as yet unknown susceptibility genes. Whole | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY M | $245,008 | Contract | : Henry M Jackson Foundation has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of 111 cases of breast ductal carcinoma; 32 cases of breast lobular carc | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| UNIVERSITY OF IOWA, THE | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Funds are requested to upgrade the ultrasound imaging capabilities of The Cardiovascular Phenotype Core at the University of Iowa. The Core was founded with NIH support in 2002, and has completed over 9,000 research ultrasound imaging studies in rodents w | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF TOLEDO, THE | $52,645 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Macro and microvascular diseases are the principal causes of morbidity and mortality in patients with type 1 and type 2 diabetes. Endothelial dysfunction, as evidenced by the increased release of free radicals, increas | Health and Human Services, Department of / National Institutes of Health | 3/09/2010 |
| UNIVERSITY OF UTAH, THE | $270,900 | Grant | Trans-NIH Recovery Act Research Support: The goal of the project is to identify deletion strains that have phenotypes of interest to each lab as a way of identifying new research projects. We propose to hire a technician for approximately 8 months to conduct this work at which time a database wo | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF NEW MEXICO | $4,964,723 | Grant | Trans-NIH Recovery Act Research Support: This project will renovate 9,63 square feet in the UNM Logan Hall (building 34) for the Clinical Neurosciences Core Facility. The project will consolidate and upgrade existing facilities and facilitate development of new research programs and early stage | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| WHITMAN COLLEGE, INC | $222,814 | Grant | Trans-NIH Recovery Act Research Support: This National Institutes of Health AREA award will permit novel research at Whitman College in the area of developmental neurobiology. The proposed studies characterize the relationship between glial cells and synapse development. There is a diverse array | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $162,325 | Grant | Trans-NIH Recovery Act Research Support: Structure and Dynamics of Membrane Proteins from NMR Orientational Constraints Nearly 30% of the human proteome is predicted to consist of membrane proteins. Despite their functional importance and frequency of occurrence, only a ~100 unique membrane prot | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| EAST TENNESSEE STATE UNIVERSITY | $9,127,509 | Grant | National Center for Research Resources, Recovery Act Construction Support: The James H. Quillen College of Medicine at East Tennessee State University was founded in 1974. Building 119 (105,000 sq ft) was completed in 1983 and was originally constructed for research and teaching. Today, this buildingng is used for research and hou... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| PURDUE UNIVERSITY | $14,902,414 | Grant | National Center for Research Resources, Recovery Act Construction Support: The NCRR ARRA C06 program provides an opportunity to build a disease research focused laboratory facility at Purdue University. The proposed 'Multidisciplinary Cancer Research Facility' (MCRF) will co-locate Purdue Center for r Cancer Research (CCR) investi... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| TRUSTEES OF DARTMOUTH COLLEGE | $152,364 | Grant | Trans-NIH Recovery Act Research Support: Asymmetric cell division creates daughter cells of different fates, and this is critical for the generation of cellular diversity. Programmed cell death or apoptosis eliminates superfluous cells, and this is critical for cellular homeostasis. Asymmetric c | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| NORTHEASTERN UNIVERSITY | $26,250 | Grant | Trans-NIH Recovery Act Research Support: Valatation and development of trypanosomal phosphodiesterase inhibitors for treat | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $15,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Colorado-Boulder plans ground-breaking for a new Systems Biotechnology Building in September, 2009. This building will provide high-quality, LEED-certified, interactive laboratory space for the Colorado Inititiative in Molecular Biotechnol... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF TENNESSEE | $39,628 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Administrative Supplement is to increase the tempo of the research funded under the parent grant by replacing worn and dated equipment and providing supplies for the studies outlined. As shown by our previous work funded by the parent | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $76,035 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application is to engineer a complex 3D artificial salivary gland using an innovative strategy combining adult salivary gland cells with a micropatterned artificial scaffold. The long-range goal of my research program is to facilitate tra | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): My goal for this career development award is to become an excellent independent investigator in patient-oriented research in chronic kidney disease progression. Chronic kidney disease (CKD) and end-stage renal disease | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $144,236 | Grant | Trans-NIH Recovery Act Research Support: We are seeking supplemental funds to facilitate the successful conductance of the NAFLD Database2 which is to begin in August 2009. During the next enrollment period which will last for 18 months, there is need for additional personnel assistance to meet | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $86,980 | Grant | Trans-NIH Recovery Act Research Support: The aim of the experiments is to identify GPR3 receptor ligands endogenous to ovarian follicles. We have also setup the reconstitution assay to measure GPR3 activation and identified some active molecules that also stimulate oocyte maturation. | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF LOUISVILLE | $9,774,453 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Louisville proposes to expand the existing Center for Predictive Medicine (CPM) Regional Biocontainment Laboratory (RBL) to support work with select agents utilizing rodents, rabbits and ferrets as animal mododels in long term efficacy/pro... Show more | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| CASE WESTERN RESERVE UNIVERSITY | $62,037 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the ARRA funds awarded is to replace aging or broken equipment which is important to carry out the research projects supported by the parent grant. The goal of the parent grant is to study the structure-function relationship for a family o | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| TEXAS BIOMEDICAL RESEARCH INSTITUTE | $27,710 | Grant | Trans-NIH Recovery Act Research Support: Neurobehavioral Family Study of Schizophrenia is a Multiplex Multigenerational Investigation (MGI) of three collaborative RO1s that combine genetic and neurobiologic paradigms to advance the understanding of pathogenesis and detection of genes that modula | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $164,360 | Grant | Trans-NIH Recovery Act Research Support: This revised submission is for the competitive renewal of a Bridge to the Baccalaureate Degree Program. The University of Minnesota Duluth has a long established consortium with two community colleges: Lake Superior College and Fond du Lac Tribal and Comm | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| UNIVERSITY OF LOUISVILLE | $90,112 | Grant | Trans-NIH Recovery Act Research Support: Supplement/Intracellular Energy Delivery and Diabetic WoundsThe long-term goal of our program is to develop a safe and effective technique to combat various tissue ischemic damages. The specific aim of this proposal is to use our newly developed proprieta | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| WAKE FOREST UNIVERSITY | $83,620 | Grant | Trans-NIH Recovery Act Research Support: Kidney stone disease is a significant health problem that consumes billions of dollars annually in health care costs and lost productivity. The bulk of these stones consist primarily of calcium oxalate. The amount of calcium and oxalate in urine are thus | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| THERALOGICS,INC | $234,764 | Grant | ARRA Accelerating Adoption of Comparative Effectiveness Research (CER): This supplemental proposal investigates a new compound that can block the white cells that cause Graft vs. Host Disease (GVHD) and the proteins that cause the symptoms associated with GVHD. | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| SIEMENS MEDICAL SOLUTIONS USA, INC. | $2,860,450 | Contract | : This report includes two projects to be completed. The first is a TurnKey Project for the preparation of the room for the installation of the Biograph mCT unit. The following Scope of Work defines the construction necessary to facilitate the installatio | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Our research program centers on achieving a comprehensive molecular understanding of human polycystic liver and kidney disease. Our goal is discovery novel paradigms for effective treatment of patients. We have taken an approach that begins with disease g | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| EMS ACQUISITION CORP. | $10,725 | Contract | : Plunge Freezer | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND | $100,001 | Grant | Trans-NIH Recovery Act Research Support: MicroRNAs bind to sites in target mRNAs' 3'UTR and (principally) inhibit translation to protein. Since binding of microRNAs does not depend on full complementarity with their target sequences, microRNAs can bind to and block protein translation of many di | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| BIOSENSE TECHNOLOGIES, INC. | $26,054 | Grant | Trans-NIH Recovery Act Research Support: A low-cost optical-based instrument is proposed for the real-time diagnosis of urinary tract infections (UTI) at the point of care. A primary innovation of the instrument is the incorporation of inexpensive mass produced optical components such as high po | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| DUKE UNIVERSITY | $478,576 | Grant | Trans-NIH Recovery Act Research Support: This study will examine maturation of vasomotor tone by measuring central and peripheral body temperature of 30 extremely low birth weight (ELBW) infants in relationship to peripheral perfusion during the first 5 days of life. We will examine the ability | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| NORTH CAROLINA STATE UNIVERSITY | $102,393 | Grant | Trans-NIH Recovery Act Research Support: We are proposing to enhance and accelerate our efforts in our research collaborations with scientists and physicians investigating the progression of HIV and related viruses. The research proposed in our parent grant, which expands on our success in a pre | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $433,125 | Grant | Trans-NIH Recovery Act Research Support: Novel approaches to treating nicotine dependence remain a priority. The transdermal nicotine patch is the most widely used form of tobacco dependence treatment, but only ~1 in 5 smokers who use this treatment achieve cessation. One factor that may contrib | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| WAKE FOREST UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This ongoing project previously demonstrated linkage of type 2 diabetes (T2DM) to chromosome 1q21-q24 in Caucasians, and more recently in African American subjects. Data from the last funding period show convincingly that although replicating well across | Health and Human Services, Department of / National Institutes of Health | 3/14/2010 |
| TRUSTEES OF TUFTS COLLEGE INC | $390,260 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to continue investigate the role of the ubiquitin-proteasome pathway in maintance of the transparacy of the eye. In this grant period, we directly test the role of the UPP in maintaining lens transparency via impairing the UPP | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $51,910 | Grant | Trans-NIH Recovery Act Research Support: Urinary Incontinence Treatment Network (UITN): ValUE: Value of Urodynamic Evaluation The primary aim of this randomized clinical trial is to determine if women desiring surgery for diagnosed, uncomplicated predominant stress urinary incontinence (UI) who | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $40,560 | Grant | Trans-NIH Recovery Act Research Support: This award, as funded, provided funds exclusively for upgrading the light source, shutters, digital video camera, imaging software and computer of an pre-existing imaging station in the Principal Investigator?s laboratory. None of the requested salary mon | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $9,492,078 | Grant | National Center for Research Resources, Recovery Act Construction Support: We request funds to renovate and improve existing spaces to provide lab and office areas for the Rutgers University Cell and DNA Repository (RUCDR), the designated core biosample processing and repository facility of four NIH H Institutes; Alcohol and Alcoh... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $67,447 | Grant | Trans-NIH Recovery Act Research Support: Lactase non-persistence (adult-type hypolactasia) results in digestive system malabsorption of lactose, the carbohydrate macronutrient present in milk. Human DNA sequence variants associated with intestinal lactase persistence and non-persistence have rec | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $41,731 | Grant | Trans-NIH Recovery Act Research Support: A key component of the parent grant that this supplement supports is the measurement of phospholipase and triglyceride lipase activities in plasma from a variety of mouse models and human subjects. Using a systematic approach, we will use these assays to | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $280,478 | Grant | Trans-NIH Recovery Act Research Support: Active retinopathy of prematurity (ROP), which is known to be a response to retinal hypoxia, occurs at the age of rapid rod outer segment development. The investigators postulate that rapidly increasing oxygen demands of the developing rods contribute to | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| BIO SIGNAL GROUP CORP | $2,949,240 | Grant | Trans-NIH Recovery Act Research Support: Of the 119 million patients in U.S. hospital emergency departments annually, 2-10% present with altered mental status (AMS), but the electroencephalogram (EEG) is currently not among the set of rapid, first-line tests that are used to diagnose the conditi | Health and Human Services, Department of / National Institutes of Health | 3/30/2010 |
| EMORY UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Mechanisms of Tenofovir Renal Tubular Toxicity The project defines TDF renal tubular transport and mitochondrial biogenesis in TDF nephrotoxicity. Renal tubular toxicity from TDF is a recongnized side effect with incompletely understood mechanisms. The pr | Health and Human Services, Department of / National Institutes of Health | 1/06/2010 |
| NORTHWESTERN UNIVERSITY | $75,039 | Grant | Trans-NIH Recovery Act Research Support: c-Jun N-terminal protein kinase (JNK; also known as stress-activated protein kinase, SAPK) plays a central role in proliferation, differentiation, programmed cell death and transformation. Overwhelming evidence implicates that JNK is a key regulator in ma | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $93,247 | Grant | Trans-NIH Recovery Act Research Support: This award is for the purchase of equipment that will facilitate the pace of NIH - NIDDK funded research. The equipment includes: a Thermo Scientific Nanodrop Spectrophotometer; a Sorvall RC3BP+ refrigerated low speed Centrifuge; and a Sorvall RC6+ refr | Health and Human Services, Department of / National Institutes of Health | 1/30/2010 |
| CLAREMONT GRADUATE UNIVERSITY | $226,321 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to understand the neural basis involved in implicit associative processes through the imaging (fMRI) of drug-relevant memory associations. Complex associative learning and memory processes influenced by reinforcing drug use result in ne | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF MARYLAND | $182,580 | Grant | Trans-NIH Recovery Act Research Support: About 20 million children suffer from congenital and inherited eye malformations, with most defects occurring in the lens and related parts of the anterior eye segment. This supplemental application will define mutations in a gene that causes lens death | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| SAINT LOUIS UNIVERSITY | $61,938 | Grant | Trans-NIH Recovery Act Research Support: The proposed research will provide essential information in order to move the field of RNA research forward. The data that is collected from this proposed research can be used to better understand humans, bacteria, and viruses and can be utilized by other | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $80,862 | Grant | Trans-NIH Recovery Act Research Support: This NIH Administrative Supplement to R01 GM074751 Mechanical regulation of actin networks accelerates research on the assembly and regulation of the actin cytoskeleton in cells. Specifically, the administrative supplement supports development and implem | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| ILLUMINA, INC. | $18,788 | Contract | : Purchase Order# HHSN311200900249P was issued from National Institute of Health/NIA to Illumina Inc. in the amount of $18,788.00 for sequencing reagents. | Health and Human Services, Department of / National Institutes of Health | 6/09/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $100,000 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Mechanisms of C. elegans Gastrulation - Admin Supplmt The overall goal of our research is to understand the mechanisms that position cells in C. elegans gastrulation, to further understand mechanisms of morphogenesis common to all animals including | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| GYNECOLOGIC ONCOLOGY GROUP , THE | $355,685 | Contract | : The Gynecological Oncology Group has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial and cervical cases. These cases are all primary an | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| DUKE UNIVERSITY | $237,273 | Grant | Trans-NIH Recovery Act Research Support: The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has proposed the continuation and expansion of the Drug-Induced Liver Injury Network (DILIN). As described in the RFA, DILIN will evolve into a network of up to 8 Clinical Center | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $116,102 | Grant | Trans-NIH Recovery Act Research Support: Genetic Analysis of Germ Cell Immortality-ARRA One goal of this award was to expedite insertion of single-copy transgenes driven by promoters that can be expressed in specific C. elegans cell types, by obtaining one fluorescence stereomicroscope that wi | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $57,500 | Grant | Trans-NIH Recovery Act Research Support: Adiponectin, a peptide hormone mainly produced by adipocytes, is now widely recognized as an insulin sensitizer that possesses anti-diabetic, anti-inflammatory and cardioprotective properties. However, the molecular mechanisms by which adiponectin sensiti | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| THE VANDERBILT UNIVERSITY | $83,611 | Grant | Trans-NIH Recovery Act Research Support: This application requests an administrative supplement for a currently funded project, R01DK078158, to allow for purchase of a vibratome and digital camera with supporting computer as well as for support of a graduate student to accelerate completion of t | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $185,554 | Grant | Trans-NIH Recovery Act Research Support: This funding is provided for immediate hiring of a postdoctoral fellow/research associate trained in computational biology and image processing, 50% support for the current part-time research assistant plus essential equipment for the prime award. This | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF MARYLAND | $98,667 | Grant | Trans-NIH Recovery Act Research Support: Sustained hyperglycemia from diabetes causes catastrophic damage to many organs and tissues. An emerging point of view is focused on the rise in blood glucose following a meal. These blood glucose levels can be very high, and the peak concentration is mor | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes is a major health care problem that has reached crisis proportions. The disease accounts for >14% of total national health care expenditures in the US, untold losses of precious human resources, and new therapies are urgently needed. We are devel | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This applicant has proposed a program of research to prepare her for a career in academic nephrology and basic science research in the field of renal physiology/pathophysiology, specifically, AQP2 trafficking. This applicant will propose to characterize A | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| INSTITUTE FOR SYSTEMS BIOLOGY | $152,640 | Grant | Trans-NIH Recovery Act Research Support: Peroxisomes are dynamic, essential organelles that house numerous regulated metabolic pathways and respond dramatically to several external stimuli. Their function and biogenesis are linked to many human health concerns including neuropathologies, cancer, | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $68,796 | Grant | Trans-NIH Recovery Act Research Support: There is little doubt that we are in the midst of a worldwide epidemic of diabetes. Insulin resistance is recognized as a characteristic trait of the disease, defined by the inability to respond to normal circulating levels of insulin. The primary lesion | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| ORGANIX INCORPORATED | $96,281 | Grant | Trans-NIH Recovery Act Research Support: The overall scope of our Phase Two SBIR project has been to design, synthesize, and develop novel and patentable 5-HT2C-selective indole derivatives leading to the development of a clinical candidate to treat obesity, and ultimately to the approval of thi | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| UNIVERSITY OF NEBRASKA | $60,000 | Grant | Trans-NIH Recovery Act Research Support: Project summary: Holocarboxylase synthetase (HCS) plays a crucial role in the regulation of the binding of the vitamin biotin to histones in humans and other animals. Decreased biotinylation of histones in biotin-deficient human cells and animal models c | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The medical application of these studies will be directed to people with diabetes. To date the role of miRNA in islet formation remains unexplored. The studies proposed here may provide new insights with direct application to the production of insulin-pro | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| UNIVERSITY OF ILLINOIS | $80,000 | Grant | Trans-NIH Recovery Act Research Support: Equipment: Avanti J-30I: $38,700 Our Beckman J2-21 was purchased in 1979 and has been experiencing a number of problems, including: the motor was replaced in 2006, the current problems are a failing lid lock that prevents operation, a laboring condenser, | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $174,929 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The neurohypophysial hormones vasopressin (VP) and oxytocin (OT) are synthesized in the magnocellular neurons (MNCs) located within the paraventricular nucleus (PVN) and the supraoptic nucleus (SON) of the hypothalamus | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| UNIVERSITY OF WASHINGTON | $288,596 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to study how heme trafficking might impact systemic iron homeostasis. As 25 mg of iron is required daily to maintain red cell production, only 1-2 mg/d is absorbed from the GI tract, and 1-2 mg/dis lost through sloughed gastroi | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| TEXAS A & M RESEARCH FOUNDATION | $80,000 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this project is to design chromatographic methods for the isolation and identification of membrane proteins in order to aid in their proteomic analysis. Presently, membrane proteins are removed from their native biomembrane envi | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes, insulin resistance and the metabolic syndrome are associated with significantly accelerated rates of cardiovascular disease. Abnormal activation of circulating monocytes triggered by inflammatory cytokines and chemokines has been implicated in t | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| OHIO UNIVERSITY | $49,358 | Grant | Trans-NIH Recovery Act Research Support: Resistance to antibiotics is becoming a major threat to public health and we are facing a risk that available antibiotics may no longer be adequate for treatment of infectious diseases. There is a compelling need for obtaining new antibacterial compounds, | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $150,001 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this competing renewal application is to continue, expand and merge the Biliary Atresia Research Consortium (BARC) and the Cholestatic Liver Consortium (CLiC) to form the Childhood Liver Disease Research and Education Network (ChiLDREN). Ch | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| UNIVERSITY OF CHICAGO, THE | $3,376,082 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Chicago submits this proposal in response to RFA-RR-09-008 to construct The University of Chicago Biomedical Cleanroom to support basic research in biomedical science. Many forefront areas of experimental bioiomedical research rely upon cu... Show more | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| INDIANA NANOTECH, LLC | $204,777 | Grant | Trans-NIH Recovery Act Research Support: A recent clinical research report on children found that over a two-year period although there was no statistical differences in anticaries benefits between two groups using either 1000 ppm F or 400 to 550 ppm F toothpastes, there was a directional trend | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $7,690 | Grant | Trans-NIH Recovery Act Research Support: Solid experimental data links human autoimmune thyroid disease (AITD) and expression of chemokines, but the studies to date have been mostly descriptive. We have developed transgenic models to investigate the role of chemokines in AITD. We have reported t | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $235,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The overall goals of this research proposal are to identify and characterize the insulin signal transduction pathways leading to functional regulation of the protein components directly involved in the intracellular tr | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $99,803 | Grant | Trans-NIH Recovery Act Research Support: We propose to incorporate a monodisperse titania filler in dental composites, which possesses excellent biocompatibility, radiopacity, osteoconductivity, and most importantly an elastic modulus (rutile: ~ 230 GPa) approximately three times greater than th | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF TEXAS AT BROWNSVILLE | $3,993,085 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Texas at Brownsville and Texas Southmost College (UTB/TSC) is a Hispanic- Serving Institution located at the southernmost tip of Texas, in one of the most economically underprivileged and rapidly growing regigions in the nation. A primary ... Show more | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $53,309 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The immediate objective of this application is to develop and refine histotripsy (a novel, non-invasive ultrasound therapy that produces non-thermal mechanical tissue destruction) as a therapy for benign prostatic hype | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $99,997 | Grant | Trans-NIH Recovery Act Research Support: The supplement will identify and localize proteases that are activated in the pancreas and spinal cord during pancreatitis, and will define the role of these proteases in inflammation and pain. It will develop new approaches for non-invasive imaging of | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| CARNEGIE MELLON UNIVERSITY | $123,328 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of the parent grant is to collect high-resolution information on the distribution of proteins within mammalian cells and to link it to nucleotide and protein sequences. It builds on extensive prior work on development of protein tagging | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | $12,208 | Grant | Trans-NIH Recovery Act Research Support: In humans, gluten-sensitive enteropathy (GSE) is typically found in individuals genetically predisposed to celiac disease (CD), and in rhesus monkeys as well as in humans it can be induced by a gluten-containing diet. We recently performed experiments whe | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF MIAMI | $309,628 | Grant | Trans-NIH Recovery Act Research Support: Improving Hand and Arm Function in Individuals with SCI Persons with tetraplegia due to spinal cord injury (SCI) have impaired hand function. This study of repetive transcranial magnetic stimulation (sham-controlled) will determine whether this technolog | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| BECKMAN COULTER, INC. | $87,810 | Contract | : Optima L-100K Biosafe Centrifuge System, Item#A30160; NVT 100 Rotor package, Item#365898; SW 32.1 Bucket Set, Item#369693 | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In the course of a rewarding and productive 5-year K-23 award dedicated to the research and discovery of biomarkers for prostate disease, we identified what may be one of the first molecular markers of benign prostatic hyperplasia (BPH), a disease that af | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $418,424 | Grant | Trans-NIH Recovery Act Research Support: Tubulin, the major component of microtubules, undergoes a posttranslational modification that is unique to this protein. The carboxy terminal amino acid on just one of the highly homologous subunits of the tubulin heterodimer is hydrolyzed and replaced by | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $104,383 | Grant | Trans-NIH Recovery Act Research Support: My long-term goal is to understand the biological basis of visual processing at the level of neural circuits and synapses. I am pursuing this goal in the mammalian retina, a tissue comprised of ~70 cell types: ~3-4 photoreceptors (depending on species), ~ | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $500,000 | Grant | Trans-NIH Recovery Act Research Support: A commitment to provide an enterprise data storage system has become an integral part of optimization of IT support and of basic and translational research. The reseearch data storage system will be integrated into shared resources of the CCRF research d | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| UNIVERSITY OF TEXAS AT DALLAS | $229,500 | Grant | Trans-NIH Recovery Act Research Support: Peptides and proteins play fundamental roles in regulating critical biochemical pathways and often use helical structures to exert their functions. This recognizes that small molecules which can accurately represent helical structures would be of great va | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $144,236 | Grant | Trans-NIH Recovery Act Research Support: This application addresses NOT-OD-09-056: Notice of Availability of Recovery Act Funds for Administrative Supplements. We are proposing a clinical study evaluating the mechanism underlying the therapeutic response using serum samples obtained from the pat | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $184,147 | Grant | Trans-NIH Recovery Act Research Support: Protein translocations across mitochondria membranes play critical roles in mitochondria biogenesis. The protein transports from the cell cytosol to the mitochondria matrix are carried out by the translocase of the outer membrane (TOM) complex and the tra | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| WICHITA STATE UNIVERSITY | $2,190,994 | Grant | Trans-NIH Recovery Act Research Support: This award is to significantly upgrade the Wichita State University (WSU) Department of Biology Core Lab Facility and Core Facility equipment. The award is intended to ensure completion of the NIH P01 Grant Program goals and to allow expansion to facilit | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $165,589 | Grant | Trans-NIH Recovery Act Research Support: A major part of our parent grant is to fine map the Ckdbp2 locus (CKD blood pressure locus 2) and identify gene(s) conferring susceptibility to hypertension after loss of nephron mass. In this supplement, we propose to use a multi-level approach for candi | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $36,920 | Grant | Trans-NIH Recovery Act Research Support: This research proposal is based on the clinical observation that a small number of potential allergens that humans encounter account for the large majority of allergic responses. The immune system's sentinel cells, dendritic cells (DC), play a crucial rol | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $99,750 | Grant | Trans-NIH Recovery Act Research Support: FXR is essential in regulating bile acid homeostasis, and contributes to the development of cholestasis, gallstones, fatty liver disease, liver and colon tumors, and atherosclerosis. Completion of the proposed study will shed light on designing tissue-sp | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE, INC. | $497,680 | Grant | Trans-NIH Recovery Act Research Support: The Hauptman-Woodward Medical Research Institute will replace an obsolete Rigaku RU- 200 rotating anode x-ray generator with another rotating anode, the Rigaku MicroMax-007 microfocus unit. With the Micromax we are also requesting a Rigaku Saturn 944+ CCD | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| BECTON, DICKINSON AND COMPANY | $602,380 | Contract | : Purchase of Flow Cytometer | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| UNIVERSITY OF HAWAII SYSTEMS | $157,159 | Contract | : The University of Hawaii has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial and cervical cases. These cases are all primary and untrea | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $47,782 | Grant | Trans-NIH Recovery Act Research Support: Single molecule (SM) measurements are rapidly becoming commonplace in research laboratories around the world and are contributing to many areas of investigation because of their ability to provide insight into phenomena that were previously intractable be | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| CORNELL UNIVERSITY, INC | $172,334 | Grant | Trans-NIH Recovery Act Research Support: Recent developments in dog (Canis familiaris) genomics have catapulted this species to the status of a model organism, with major advantages for the study of complex genetic diseases and traits relevant to the human condition. Its rapid rise in genomics w | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| WAYNE STATE UNIVERSITY (INC) | $99,974 | Grant | Trans-NIH Recovery Act Research Support: Retinopathy, one of the most debilitating complications of diabetes, is the leading cause of acquired blindness among young adults. The clinical studies have shown that retinopathy resists arrest after good control is initiated, and the carry-over effect | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an NIMH Patient-Oriented Research Career Development Award (K-23) entitled The Neural Basis of Delusions in Schizophrenia: Studies of Emotional Perception. The candidate's interest is in the study of the neural correlates of psy | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $24,995 | Grant | Trans-NIH Recovery Act Research Support: Not Started | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| PICOQUANT PHOTONICS NORTH AMER | $443,938 | Contract | : MT200 confocal fluorescence lifetime and FCS microscope | Health and Human Services, Department of / National Institutes of Health | 11/10/2009 |
| BAYLOR COLLEGE OF MEDICINE | $0 | Grant | Trans-NIH Recovery Act Research Support: scientific purpose of this project supplement is to accelerate the pace of discovery of the underlying mechanisms for intracellular calcium?s triggering of plasticity of synaptic connections between nerve cells within the visual cortex. The economic purp | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $265,452 | Grant | Trans-NIH Recovery Act Research Support: The work proposed for supplemental funding is directly responsive to the National Institute of Mental Health (NIMH) Strategic Plan. Specifically, our work will further develop designs for intervention studies. Our preliminary work combining claims data | Health and Human Services, Department of / National Institutes of Health | 3/01/2010 |
| UNIVERSITY OF CHICAGO, THE | $53,320 | Grant | Trans-NIH Recovery Act Research Support: My ultimate goal is to become a fully independent principal investigator with a basic science laboratory examining the molecular physiology of renal ion transport. After completing 6 years of training with Dr. Steven Herbert at 3 different institutions, I | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $168,832 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this research is the elucidation of the mechanism of action of the aire gene, which encodes a protein primarily expressed in the thymic epithelium and which is essential for the proper acquisition of immune tolerance in T lymphocytes. | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| TRINITY UNIVERSITY | $485,591 | Grant | Trans-NIH Recovery Act Research Support: In this research application, we seek to examine the topography of the corpus callosum (CC) at both the macrostructural and microstructural levels in primates. Comparative study of the primate CC is significant as this structure is believed to be fundame | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| NORTHWESTERN UNIVERSITY | $193,327 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to understand the structure and function of the PNC and its roles in malignancy. The perinucleolar compartment (PNC) is a multicomponent non-membrane bound nuclear substructure that localizes to the nucleolar periphery. We have found | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $82,495 | Grant | Trans-NIH Recovery Act Research Support: The assembly of cells into tissues depends upon formation of intercellular junctions. In adherens junctions, the catenins link transmembrane cadherin cell adhesion molecules to the actin-based cytoskeleton, and in desmosomes an analogous protein assembly | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| THOMAS JEFFERSON UNIVERSITY | $106,755 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the proposal are to investigate: 1] The role of the C- terminal domain in channel gating. Deletion of 60aa from the C-terminal tail or 10aa from the cytosol- exposed loop between TM domains 4 & 5 cause loss of channel function. Point | Health and Human Services, Department of / National Institutes of Health | 3/30/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $30,515 | Grant | Trans-NIH Recovery Act Research Support: Osteocytes comprise over 90% of all bone cells, yet little is known of their function(s) or of the involvement of systemic hormones in regulating their activity. These cells reside in the lacunae deep within the mineralized matrix of bone and communicate | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $15,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: DESCRIPTION (provided by applicant): The Animal Resource Program at MIT represents a vital resource that is central to the various biomedical research missions of the Institute. This award provides funds to renovate and equip p the E25 animal facility in a ... Show more | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| THE VANDERBILT UNIVERSITY | $139,485 | Grant | Trans-NIH Recovery Act Research Support: This is a request for the purchase of specialized instrumentation to expand acquisition of samples for BioVU, the Vanderbilt DNA databank, into the pediatric population. The challenges to improve child health surround us - regionally, nationally, and glob | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $201,257 | Grant | Trans-NIH Recovery Act Research Support: The award is an administrative supplement to NIH grant R01 GM072700. Please note that the research described in this Administrative Supplement request does not include activities that are beyond the parent project?s IRG-approved scope. During the origina | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| EMORY UNIVERSITY | $139,709 | Grant | Trans-NIH Recovery Act Research Support: TYPHOON PHOSPHORIMAGER. This is an instrumentation grant. This proposal seeks to obtain funds to purchase a Typhoon Trio Imager. Such imagers allow the capture, image construction, quantitative analyses, and production of publication images from numerous | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF TEXAS AT AUSTIN | $68,096 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the proposed research is to provide quantitative understanding of the relationship between neural activity in the primate visual cortex (V1) and behavioral performance in pattern detection tasks. To achieve this goal, monkeys will be t | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $185,148 | Grant | Trans-NIH Recovery Act Research Support: This application is submitted in response to the NIH Notice Number (NOT-OD-09-058) and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications as a revision of an ongoing grant (R01 EY015293) entitled 'Calo | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| TRUSTEES OF TUFTS COLLEGE INC | $638,930 | Grant | National Center for Research Resources, Recovery Act Construction Support: In this proposal we request funding to create an intellectually- and technologically-advanced research environment focused on understanding the patterns and mechanisms of normal development and disease progression using a multlti-scale approach-from genome ... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| CEDARS-SINAI MEDICAL CENTER | $151,979 | Grant | Trans-NIH Recovery Act Research Support: The study goal is to identify potential causes of insulin resistance in Polycystic Ovary Syndrome | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $99,135 | Grant | Trans-NIH Recovery Act Research Support: Vacuolar ATPases (V-ATPases; V1VO-ATPases) are large, multi subunit protein complexes found in the endomembrane system of eukaryotic organisms where they function to acidify the interior of subcellular compartments. In polarized cells of higher eukaryotes | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| JS TECHNOLOGY, INC | $59,800 | Contract | : Additional administrative support to increase compliance oversight activities resulting from the influx of ARRA grants. | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| WASHINGTON UNIVERSITY, THE | $149,061 | Grant | Trans-NIH Recovery Act Research Support: In this study, we aim to identify gene products responsible for traits dependent upon the epigenetic element known as the yeast (PSI plus) prion. This system enables detailed investigation into the underlying mechanisms of phenotypic expression of comple | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Perinatal Risk Factors and Genetic Susceptiblity for Childhoold Psychopathology. To examine the transduction of maternal psychological characteristics through the placenta into fetal epigenetic marks during the course of pregnancy in order to evaluate t | Health and Human Services, Department of / National Institutes of Health | 2/22/2010 |
| HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE, INC. | $269,251 | Grant | Trans-NIH Recovery Act Research Support: Pathogens such as Pneumocystis (P), Toxoplasma gondii (Tg)and Mycobacterium avium (Ma) are major causes of opportunistic infection and mortality in immunocompromised patients, particularly those with AIDS. Pneumocystis organisms represent a large group of | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $100,482 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The Atomic Force Microscope (AFM) can image and manipulate biological samples under physiological conditions at nanometer resolution. Despite its very slow operation (sometimes over 30 minutes per image) and the specia | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| BLOODCENTER OF WISCONSIN, INC. | $2,932,669 | Grant | National Center for Research Resources, Recovery Act Construction Support: The overall goal of this application is to convert shelled space in the BRI into finished laboratory space in order to grow the Stem Cell Program. The objectives are to: 1) build-out the shelled space into finished laboratory y space; 2) relocate the labora... Show more | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| WELLS JR, WILLIAM G | $19,500 | Contract | : Grants Management Support for ARRA Projects | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| COMPUTER SCIENCES CORPORATION | $1,502,999 | Contract | : Add NCI Clinical Research Data to BTRIS | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $150,001 | Grant | Trans-NIH Recovery Act Research Support: This is the final report for this award. The project is complete, but the research effort did not exhaust the funds awarded. Closeout documents have been submitted to the National Institute of (fill in) for processing and the remainder of the award is | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| UNIVERSITY OF FLORIDA | $62,928 | Grant | Trans-NIH Recovery Act Research Support: The main criterion in assessing the therapeutic efficacy of tissue engineered construct is the successful restoration of the host's physiology. Direct and non-invasive in vivo monitoring of a construct is of great importance for the following reasons: it | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF PITTSBURGH THE | $498,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of this proposal is to acquire a high-resolution ultrasound imaging system for use in biomedical research using small animals spanning the size of mice embryos to rabbits. This first and only commercially available high-frequency, high-resol | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| NORTHWESTERN UNIVERSITY | $329,139 | Grant | Trans-NIH Recovery Act Research Support: Disruptive behavior disorders (DBDs), including Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD), are among the best, empirically documented forms of early childhood psychopathology. Recent studies have demonstrated that DBDs are identifiable | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| NORTHWESTERN UNIVERSITY | $97,701 | Grant | Trans-NIH Recovery Act Research Support: We have proposed to purchase a fluorescence microscope, an essential equipment for our study that aims to investigate a novel gene called Sirt1 in type 1 diabetes development and therapy. | Health and Human Services, Department of / National Institutes of Health | 2/28/2010 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $1,967,936 | Grant | Trans-NIH Recovery Act Research Support: This application details the expansion and upgrade of a Clinical Vector Core facility at The Children's Hospital of Philadelphia (CHOP). We are proposing the construction of a new manufacturing suite and the simultaneous renovation of an existing cGMP man | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $31,775 | Grant | Trans-NIH Recovery Act Research Support: This Recovery Act Administrative Supplement to R01 DK70844, Transplantation of Reduced-Size Fatty Livers is for purchasing a real-time PCR detection system. The overall objective of this research is to expend the usable donor pool and improve the outcome | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $104,771 | Grant | Trans-NIH Recovery Act Research Support: The NIDDK NASH Clinical Research Network (CRN) has recently completed a clinical trial of pioglitazone or vitamin E for nonalcoholic steatohepatitis (NASH). This study demonstrates that vitamin E (800 IU/day) is superior to placebo for treatment of NASH a | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In the setting of end-stage bladder disease, current bladder replacement techniques involve the use of intestinal segments, which are associated with significant perioperative morbidity and long-term complications. Combining tissue engineering techniques | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Liver-directed cell therapy has siginificant potential for many disorders. Studies of hepatocyte transplantation provided insights into cell therapy, as well as novel models for basic studies concerning liver regeneration and stem cell biology. We now wis | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $139,750 | Grant | Trans-NIH Recovery Act Research Support: In our parent grant, we proposed to study the role and action mechanism of a newly identified nuclear coregulator ATAAB/ANCCA in mediating estrogen signaling pathways in normal hormone-sensitive mammary gland and in estrogen receptor (ER) positive breast | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| RECINTO UNIVERSITARIO MAYAGUEZ | $855,842 | Grant | Trans-NIH Recovery Act Research Support: Weight control does not seem to be an effective answer to the increasing incidence of obesity as studies have shown that within five years most people have regained whatever weight they lost. Finding a solution to childhood overweigh/obesity is especiall | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $99,996 | Grant | Trans-NIH Recovery Act Research Support: GENETIC EPIDEMIOLOGY OF BODY MASS INDEX, ADIPOSITY AND WEIGHT GAIN ARRA. The purpose of this administrative supplement is to accelerate the tempo of analysis to identify genetic variants associated with obesity-related traits by supporting a postdoctoral | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| POLYWELL COMPANY, INC. | $1,887,652 | Contract | : BARCODING DLIEVERY SYSTEM, WORKSTATIONS ON WHEELS | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $104,423 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a Recovery Act Administrative Supplement under the notice NOT -OD-09-056 for a research grant ROl GM056836. The general goal is to define molecular mechanisms responsible for the regulation of cell polarity and cytokinesis. For | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| PLX PHARMA INC | $37,500 | Grant | Trans-NIH Recovery Act Research Support: PLx Pharma is a pharmaceutical company developing GI safer formulations of proven non-steroidal anti-inflammatory drugs (NSAIDs) including ibuprofen, aspirin and naproxen for prescription and over-the-counter markets. PLx has created novel NSAID formulati | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK INC | $100,902 | Grant | Trans-NIH Recovery Act Research Support: Purchase College, State University of New York is partnering with Dutchess Community College, Rockland Community College and Sullivan County Community College to increase the number of students from underrepresented groups (primarily African Americans an | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,491 | Grant | Trans-NIH Recovery Act Research Support: The central theme of the Program Project Is focused on mechanisms that determine innate and acquired immune responses in the intestinal mucosa to enteric microbes and microbial products, and the consequent mucosal protective immune and inflammatory respon | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF ARKANSAS SYSTEM | $10,458,675 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Winthrop P. Rockefeller Cancer Institute at the University of Arkansas for Medical Sciences is an emerging cancer center with areas of expertise in, amongst others: personalized medicine for multiple myeloma based on gene e expression profiling; pharmac... Show more | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $106,981 | Grant | Trans-NIH Recovery Act Research Support: This project is focuses on a protein called Mad3 that is involved in promoting high fidelity partitioning of chromosomes to daughter cells during cell division. In mitotic cell divisions Mad3 is part of a surveillance mechanism, termed the spindle check | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $383,980 | Grant | Trans-NIH Recovery Act Research Support: This proposal for a secondary analysis of data collected in a parent ethnographic study of end-of-life decision making (EOLDM) in intensive care units (ICUs). The current proposal uses qualitative description to focus on the roles of key persons in EOLDM | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $94,794 | Grant | Trans-NIH Recovery Act Research Support: The increase in the number of patients with end stage liver disease has led to rapid growth of the waitlist for transplantation and increased efforts to enlarge the donor pool with and adult-to-adult living donor (LD) liver transplantation. Fundamental di | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| TURNER BIOSYSTEMS, INC. | $19,656 | Contract | : Modulus Microplate Luminometer | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $75,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Heparan sulfates (HS) are abundantly expressed on the cell surface and in the extracellular matrix as proteoglycans with differential sulfation pattern, chain length and number of chains leading to vast structural feat | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF PITTSBURGH THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: We have identified a novel intracellular signaling molecule in the beta cell, atypical protein kinase C zeta (PKC zeta) that (i) markedly increases rodent and human basal beta cell proliferation; and, (ii) is responsible for glucose-mediated beta cell pr | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| NEW YORK UNIVERSITY (INC) | $68,786 | Grant | Trans-NIH Recovery Act Research Support: A key paradigm in urothelial biology is that urothelial umbrella cells can reversibly adjust its apical cell surface area. Thus bladder expansion can trigger the cytoplasmic fusiform vesicles to fuse with the apical surface, while bladder contraction can | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $100,000 | Grant | Trans-NIH Recovery Act Research Support: We have assembled a substantial amount of proteomic and genomic data to create a comprehensive molecular profile of tissue samples of hepatocellular carcinoma (HCC or liver cancer) as well as a molecular profile of the associated plasma. We have also ide | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| UNIVERSITY OF CHICAGO, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Hypertension represents a major public health concern. To date, each form of inherited hypertension has been linked to defective salt handling in the kidney. This application seeks to explore the mechanisms involved in the regulation of one of the key sal | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF SOUTH FLORIDA | $416,397 | Grant | Trans-NIH Recovery Act Research Support: Our laboratory has provided a unique perspective of endothelial health, showing that argininosuccinate synthase (AS) of the citrulline-nitric oxide cycle must be functional to sustain nitric oxide (NO) production and to maintain cell viability. Since virt | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $178,230 | Contract | : The Sloan Kettering Institution for Cancer Research has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial cases. These cases are all prim | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| SIGMA-ALDRICH CORPORATION | $34,933 | Contract | : The overall purpose of the solicitation and award to RFQ-NCI-90254-MM Doubly Labeled Water Isotopes for the Biomarker-Based Validation of Diet and Physical Activity Assessement Tools in Existing Cohorts is to support NCI's Observing Protein and Energy Nu | Health and Human Services, Department of / National Institutes of Health | 9/29/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $153,193 | Grant | Trans-NIH Recovery Act Research Support: The experiments proposed in this application investigate the roles of dendritic spine growth and retraction in experience-dependent plasticity in the mouse visual cortex. Recent evidence indicate that dendritic spines are dynamic in the developing and adu | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $85,598 | Grant | Trans-NIH Recovery Act Research Support: In this supplement to R01GM070539, almost all of the reactions carried out by cells are done by proteins. When and where these proteins acted is regulated by their destruction. This destruction of these proteins is carried out by a cellular machine the | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $306,400 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplemental request involves 5 projects under the umbrella of the A2ALL UO1. Each of the projects addresses a specific aim of the parent grant, with the goal to complete data collection, standardize results, or accelerate sample analy | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| DELL MARKETING L.P. | $100,186 | Contract | : Enterprise Systems | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $100,023 | Grant | Trans-NIH Recovery Act Research Support: Herpes simplex virus is the major infectious cause of blindness in the US. Herpes keratitis is associated with repeated bouts of reinfection of the cornea by virus derived from sensory neurons HSV particles are transported within neuronal axons from sens | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF ARKANSAS SYSTEM | $99,850 | Grant | Trans-NIH Recovery Act Research Support: The long?term goal of the parent R01 is to definitively assess biotin status during normal human pregnancy. Here we seek supplemental funding to pursue an unexpected, exciting opportunity to develop, validate, and apply a novel indicator of biotin status | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $252,780 | Grant | Trans-NIH Recovery Act Research Support: Numerous human disorders arise from microdeletions and microduplications of relatively large genomic regions. These rearrangements can result in copy number alterations (CNAs) of one or more genes. Conditions arising from microdeletions and microduplicati | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| WASHINGTON UNIVERSITY, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This grant application is focused on how abnormalities in cellular processing and distribution of the membrane protein CD36 can impact uptake and metabolic targeting of FA. CD36 is a major facilitator of FA uptake in vivo and important to cellular ability | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| THE VANDERBILT UNIVERSITY | $45,728 | Grant | Trans-NIH Recovery Act Research Support: The protein serine-threonine phosphatase 2A (PP2A) family of enzymes participates in a wide spectrum of cellular functions including cell growth, differentiation, cell cycle progression, and apoptosis. Multiple regulatory mechanisms control the activity | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| CDW GOVERNMENT LLC | $1,300,049 | Contract | : Disaster Recovery Equipment | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| THOMAS JEFFERSON UNIVERSITY | $6,651,849 | Grant | National Center for Research Resources, Recovery Act Construction Support: Thomas Jefferson University has determined that Jefferson Alumni Hall (JAH), which was constructed in 1968, has at least 40 more years of useful life from the perspective of its structural integrity. However, the laboratories s require renovation to meet mo... Show more | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $1,356,449 | Grant | Trans-NIH Recovery Act Research Support: The Forsyth Institute, the world's leader in oral and craniofacial disease research, requests funds to renovate 606 ft2 for a new state-of-the-art data center core at its new research facility at 245 First Street, Cambridge, MA. The data center will suppo | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $72,306 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research is to understand the molecular mechanism of proteins that regulate microtubule (MT) polymerization and depolymerization. These proteins act as tubulin polymerase and depolymerases accelerating tubulin incorporation and dissociati | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| ADVANCED LIQUID LOGIC INC. | $189,378 | Grant | Trans-NIH Recovery Act Research Support: This is a phase I SBIR proposal that aims to demonstrate a near patient platform for screening neonates with very high levels of bilirubin (hyperbilirubinemia). The proposed devise would be greatly useful in rapid identification and enable early treatment | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $80,000 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award is for equipment only. The award is approved to purchase biophotonic equipment designed to conduct TIRF experiments. The equipment to be aquired include: Laser, TIRF illuminator, dual view system, high-quality CCD cameras and the software | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $101,270 | Grant | Trans-NIH Recovery Act Research Support: This proposal will further our understanding of GI development and cancer, and allow for the development of novel diagnostic and possibly therapeutic tools in the future. The current proposal has created one additional job in the biomedical research fiel | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| COLLEGE OF WILLIAM & MARY, THE | $40,512 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this funding is to provide an administrative supplement the existing NIH (Non-ARRA) Grant R15 GM085792 to Oliver Kerscher which was funded 6/11/2008. | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| Z-TECH CORPORATION | $300,000 | Contract | : Acquire Additional Staffing for the eRA Systems Engineering Support Services | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| ARIZONA STATE UNIVERSITY | $192,940 | Grant | Trans-NIH Recovery Act Research Support: The Aims of the proposal for supplemental funds to R01DK081750 are: 1. To accelerate both the pace and quality of mass spectrometry analysis by providing an equipment upgrade to the LTQ/FTICR mass spectrometer that will increase its sensitivity. 2. | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF MIAMI | $14,821,565 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Neuroscience & Health Annex will create an interactive hub for interdisciplinary research and will provide facilities to be shared by scientists from the College of Arts and Sciences and the Miller School of Medicine. Thihis new facility will provide s... Show more | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| COLORADO STATE UNIVERSITY | $127,981 | Grant | Trans-NIH Recovery Act Research Support: Metnase is a human protein with a SET (lysine methylase) domain and a Mariner transposase (nuclease) domain. Metnase is implicated in several aspects of DNA dynamics. Metnase promotes integration of DNA in a sequence-independent manner, but it is not know | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $14,984,116 | Grant | National Center for Research Resources, Recovery Act Construction Support: This proposal is for an infrastructure upgrade and modernization of the laboratory facilities housed in the North Wing of the principal building of the Johns Hopkins Bloomberg School of Public Health (JHSPH). The JHSPH, foundeded in 1916, is the oldest and ... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF CINCINNATI | $4,819,500 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Department of Environmental Health at the University of Cincinnati is a world leader in environmental and occupational health, with over $22M in external research in 2008. The building that houses this department is showining its age, with one wing alre... Show more | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| STEMCELLS, INC. | $98,685 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant 1R43DK083104-01, Towards the creation of HCV-resistant liver cells for transplantation is to develop a transplantable HCV resistant cell product by silencing endogenous genes necessary for HCV infection/transmission. | Health and Human Services, Department of / National Institutes of Health | 3/01/2010 |
| AMERICAN PEST MANAGEMENT INC | $135,400 | Contract | : Pest management services to support three renovation projects at the National Institutes of Health, Bethesda, MD. | Health and Human Services, Department of / National Institutes of Health | 3/02/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $177,500 | Grant | Trans-NIH Recovery Act Research Support: This is a supplemental request to the parent grant, Catenin & Cadherin Signaling in Development and Cancer, that will not add to the scope or specific aims. Rather it will provide funds for the retention of key personnel whose positions were supported by | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF MARYLAND | $5,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: With the assistance of the National Center of Research Resources, National Institutes of Health, Department of Health and Human Services and funds awarded under the American Recovery Act Limited Competition: Extramural Researcrch Facilities Improvement Prog... Show more | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| MERLIN INTERNATIONAL, INC. | $739,310 | Contract | : Computer Associates Web Identity Access Management SW and Maint | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| TECAN US INC. | $550,000 | Contract | : DNA Sample processing work cell. | Health and Human Services, Department of / National Institutes of Health | 10/08/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $98,566 | Grant | Trans-NIH Recovery Act Research Support: We are studying proteins that prevent inflammation. We have discovered that A20 is a normal protein in all our cells that prevents inflammation. We have found that A20 blocks inflammation by inhibiting activating signals in immune cells. We have also f | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF OREGON | $9,117,040 | Grant | National Center for Research Resources, Recovery Act Construction Support: Our goal is to expand and renovate core zebrafish facilities at the University of Oregon (UO) to increase productivity and impact of PHS (Public Health Service) funded research and to promote safety and welfare of research aninimals, researchers, and animal... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $411,627 | Grant | Trans-NIH Recovery Act Research Support: This application requests funds to purchase a Hitachi Model H-7650 Biological, 120kv, transmission electron microscope (TEM) with a Gatan 11megapixel CCD camera for high resolution imaging of fixed biological samples. This instrument will be a shared reso | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $125,437 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent proposal (GM069420) is to develop synthetic transcriptional regulators using modular assembly of functional domains. Based on the architecture of natural transcription factors we hypothesized that tethering synthetic DNA | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| UNIVERSITY OF MONTANA SYSTEM | $421,525 | Grant | Trans-NIH Recovery Act Research Support: Multiple signals determine cell fates such as cell birth, death and differentiation during development and in adult multicellular organisms. A major challenge in biology is to understand how signals from different receptors are integrated to determine an | Health and Human Services, Department of / National Institutes of Health | 3/30/2010 |
| UNIVERSITY OF ILLINOIS | $9,915,615 | Grant | National Center for Research Resources, Recovery Act Construction Support: The College of Dentistry proposes to renovate 23,000 square feet of space into up-to-date, LEED certified research space. This project will add at least 9,000 square feet of new research space and renovate approximately 14,00000 square feet of poorly confi... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This shared instrumentation grant request funds to partially offset the cost of an upgrade of the current 3 Tesla whole body magnetic resonance imaging (MRI) system at the UCSD Center for Functional MRI (CFMRI). In comparison to our existing system, the u | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $32,681 | Grant | Trans-NIH Recovery Act Research Support: About 75% of birth defects involve the head, face, and oral tissues. Although orofacial clefts and other craniofacial malformations have clear environmental and genetic causes, insufficient information exists concerning the mechanisms of craniofacial deve | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $499,000 | Grant | Trans-NIH Recovery Act Research Support: This award is for the purchase of a Becton Dickinson Influx Flow Cytometer. This instrument will be configured with a biological safety cabinet that will permit the sorting and/or analysis of primary human cell populations, as well as primary cells and ce | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $495,000 | Grant | Trans-NIH Recovery Act Research Support: Funding is requested to upgrade a 12-year-old 600 MHz MR spectrometer with a Bruker Biospin AVANCE IIINMR Console, quadruple resonance inverse detection QCI CryoProbe, and SampleJet automated sample changer. The requested equipment will be installed on an | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $99,841 | Grant | Trans-NIH Recovery Act Research Support: Project Summary. Biliary atresia (BA) is a progressive, inflammatory, sclerosing extrahepatic and intrahepatic cholangiopathy which presents in infancy and leads to bile duct obstruction and biliary cirrhosis. Intrahepatic biliary inflammation and scleros | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $176,047 | Grant | Trans-NIH Recovery Act Research Support: The focus of our original submission was on the use of NMR spectroscopy to determine the structure and understand the mechanism of the integral membrane enzyme DsbB. Four aims were included in the funded grant: Aim 1: Determination of the solution structu | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $149,143 | Grant | Trans-NIH Recovery Act Research Support: The optic nerve is an accessible and anatomically simple part of the central nervous system (CNS) that has long been used to investigate the development and regeneration of CNS connections. Like most neurons in the CNS, retinal ganglion cells (RGCs), the | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF ILLINOIS | $235,500 | Grant | Trans-NIH Recovery Act Research Support: Our long term objective is to understand the essential roles of regulatory carboxypeptidases in physiological and pathological processes. Membrane-bound carboxypeptidase (CP) M is an important regulator of the kallikrein-kinin system via its ability to g | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| BANNER HEALTH | $6,530,203 | Grant | National Center for Research Resources, Recovery Act Construction Support: This application requests funds for the renovation of existing space as well as for a small building addition that will allow us to relocate and expand our nearly 20 year old cyclotron and radiochemistry laboratory, Positron E Emission Tomography (PET) imag... Show more | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $159,460 | Grant | Trans-NIH Recovery Act Research Support: This request is for funds to purchase a nucleic acid extraction system consisting of an AutoGenFlex Star automated DNA isolation system and the AutoGen Quick-Gene 810 RNA isolation unit. The instruments will be housed, managed, and maintained by the India | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $481,775 | Contract | : The University of North Carolina has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of breast, lung, colon, head and neck, hepatocellular, kidney, bl | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| UNIVERSITY OF PITTSBURGH THE | $227,250 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the proposed research is to elucidate the mechanisms that regulate PTH1R endocytosis and intracellular traffic. Previous work from our laboratory and others has shown that the PTH1R is internalized by a combination of arrestin-dependent a | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Hematopoietic stem cells (HSCs) both self-renew and generate all blood cell lineages for life. HSCs are born in the embryo, but relatively little is known regarding their ontogeny and early function. This is due, in large part, to these events occurring i | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $202,499 | Grant | Trans-NIH Recovery Act Research Support: ARRA supplementation at Columbia will be used to extend employment of current study personnel to complete existing study tasks, increase the pace of scientific investigation, and to add study personnel with expertise in radiologic interpretation to benef | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY | $443,945 | Grant | Trans-NIH Recovery Act Research Support: There is a fundamental gap in understanding how cytokine milieu affects the oxidative capacity of macrophages, in general, and in neonates, in particular. Systemic and pulmonary innate immune responses are highly reliant on phagocytes and their capacity f | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| TEXAS A & M RESEARCH FOUNDATION | $106,271 | Grant | Trans-NIH Recovery Act Research Support: Thiamin is an essential component of the human diet with an RDA of 1.2 mg. It is also an important commercial chemical and it is widely used as a food additive and flavoring agent. Annual production, by chemical synthesis, is on the order of 3,300 tons. T | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $297,297 | Grant | Trans-NIH Recovery Act Research Support: Studies of molecular events inside of cells have provided novel and important insights into many questions in physiology and pathology: How do cellular motors work? How does a proton pump generate ATP? How is cargo secreted from cells? How do viruses ente | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF PITTSBURGH THE | $99,452 | Grant | Trans-NIH Recovery Act Research Support: The sorting and delivery of a subset of newly synthesized proteins to the apical surface is critical for maintaining renal function. This supplement focuses on the mechanisms by which apical membrane and secreted proteins are recognized and sorted. Both | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| WASHINGTON UNIVERSITY, THE | $239,395 | Grant | Trans-NIH Recovery Act Research Support: The Washington University High Resolution NMR Facility requests funding to purchase a Varian DirectDriveT console for an aging 500 MHz NMR instrument and a magic angle sample spinning NanoprobeT to allow for studies of metabolite profiles from cancer tiss | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $1,793,470 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Beth Israel Deaconess Medical Center (BIDMC) is a 566-bed teaching hospital of Harvard Medical School (HMS) with over 114 principal investigators (PIs) engaged in NIH-funded pre-clinical and clinical cancer research. In 202006, the BIDMC was awarded a h... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| NORTHWESTERN UNIVERSITY | $87,133 | Grant | Trans-NIH Recovery Act Research Support: Dendritic cells (DCs) are potent antigen presenting cells (APCs) due to the ability to stimulate nai've T cells with antigen. DCs are also a promising new source of vaccine development. Endocytosis and migration are two key processes in the ability of DCs | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $57,413 | Grant | Trans-NIH Recovery Act Research Support: This supplemental is for a fluorescence plate reader/spectrofluorimeter combined instrument and a stereology upgrade to an existing microscope. The spectrofluorimeter will greatly speed the NAD+ and FBP/DHAP measurements proposed in Aims 1.2 and 2.2. | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $42,476 | Grant | Trans-NIH Recovery Act Research Support: The 500 Nations Haskell / KU Bridge program supports students from Haskell Indian Nations University who seek to transfer to other institutions; it works collaboratively with other MORE programs (IMSD, RISE, PREP, and IRACDA) to move American Indians into | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| VETERANS BIO-MEDICAL RESEARCH INSTITUTE INC | $374,203 | Grant | Trans-NIH Recovery Act Research Support: Motion sickness is a debilitating condition that affects a wide range of individuals in both daily life and in pathological conditions. While it is widely seen in many clinical settings, it remains difficult to objectively evaluate and treat. Recent work | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $94,311 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The ultimate goal of this proposal is to determine the cause(s) of impaired glucose tolerance leading to type 2 diabetes. An improved understanding of the underlying pathophysiology of the early events should provide a | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| EMMES CORPORATION, THE | $145,278 | Grant | Trans-NIH Recovery Act Research Support: The award provides additional funding for research design and protocol development, including definition of objectives and approaches, planning, implementation, participant recruitment and follow-up, data collection, quality control, interim data and safe | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| NEW YORK UNIVERSITY (INC) | $480,900 | Grant | Trans-NIH Recovery Act Research Support: The DNA Sequencing Facility within the Skirball Institute at New York University Langone Medical Center provides sequencing services to about 200 labs and hundreds of scientists in the NYU community. As a core facility, the sequencing lab offers state-of- | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $179,228 | Grant | Trans-NIH Recovery Act Research Support: Ionizing radiation plays a significant role in the treatment of human cancers, while exposure to relatively low doses can lead to the induction of cancer, to teratogenesis and mutagenic consequences. Laboratory studies at Columbia University have explored | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $53,000 | Grant | Trans-NIH Recovery Act Research Support: Funds were awarded to purchase an FPLC apparatus in furtherance of the specific aims of the parent grant. Due to a change in plans we received permission from NIH to instead purchase an Accuri 6 flow cytometer. | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $106,785 | Grant | Trans-NIH Recovery Act Research Support: Podocyte depletion is a hallmark of progressive glomerulosclerosis and diabetic nephropathy. CD2- associated protein (CD2AP) is a widely-expressed cytoplasmic adaptor protein that has previously been implicated in podocyte slit diaphragm protein complex f | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $99,000 | Grant | Trans-NIH Recovery Act Research Support: GENETICS ANALYSIS OF HEMATOPOIETIC DEVELOPMENT Abstract: Our goal is to understand the underlying mechanisms involved in regulating lineage specification of hematopoietic stem cells (HSC) and vascular angioblast cells from mesoderm during embryogenesis. | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $80,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): A major regulator of body composition, energy balance and food intake is leptin, an adipocytokine. Leptin circulates and has direct actions in the brain and skeletal muscle by binding to the B isoform of leptin recepto | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $99,998 | Grant | Trans-NIH Recovery Act Research Support: Inherited disorders of intrahepatic bile duct development are a major cause of morbidity and mortality in the pediatric population. In recent years, advances have been made toward understanding the genetic control of liver development, but relatively litt | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| JACKSON CONTRACTOR GROUP, INC. | $5,639,662 | Contract | : Renovation of Building #7 on the Rocky Mountain Laboratory Facility in Hamilton Montana. | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $79,028 | Grant | Trans-NIH Recovery Act Research Support: Several risks factors of the metabolic syndrome such as insulin resistance and obesity present mitochondrial dysfunction that is associated with increased intramyocellular lipid accumulation. In response to nutrients and cold stimuli, transcriptional comp | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| THE VANDERBILT UNIVERSITY | $78,876 | Grant | Trans-NIH Recovery Act Research Support: Pancreatic islets are extensively vascularized and this is important in their ability to sense the blood glucose and quickly secrete insulin. While islets receive up to 20 times more blood flow than surrounding pancreatic acinar tissue, the molecular fact | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| DISCOVERYBIOMED, INC. | $200,000 | Grant | Trans-NIH Recovery Act Research Support: This Phase 1 SBIR award was a Catalyst award under ARRA. This award was garnered based upon a program to discover novel botanical or phytochemical-derived chemicals that will be developed an future anti-inflammatory drugs for a series of chronic respirato | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| DUKE UNIVERSITY | $89,347 | Grant | Trans-NIH Recovery Act Research Support: In the approved parent grant, we proposed three specific aims, the completion of which would define the role of ERR? in breast cancer, and enhance our understanding of ERR? biology. We have now completed Aim 1 and demonstrated that ERR? activity is funct | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $454,415 | Grant | Trans-NIH Recovery Act Research Support: A group of six investigators at West Virginia University are requesting funds Vevo 2100 micro-ultrasound for real-time, 3D imaging in small animals. Although clinical ultrasounds have been routinely used in humans for years, the Vevo is the only preclini | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| BAYLOR COLLEGE OF MEDICINE | $82,900 | Grant | Trans-NIH Recovery Act Research Support: This project is focused on elucidating molecular mechanisns of skeletal abnormalities in tricho-rhino-phalangeal syndrome.Mutations of the human TRPS1 gene cause a dominantly inherited skeletal dysplasia tricho-rhino-phalangeal syndrome (TRPS). Although | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $138,614 | Grant | Trans-NIH Recovery Act Research Support: The proposed research will provide insights into ways that regeneration can be enhanced after tissue damage or injury and could impact the treatment of many diseases (e.g. heart attacks, strokes). Funds requested in the supplement will generate employment | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| SIEMENS MEDICAL SOLUTIONS USA, INC. | $67,780 | Contract | : syngo-? CT Oncology is a comprehensive software solution designed to fast-track routine diagnostic oncology, staging, and follow-up. It provides a range of fully automated tools specifically designed to support physicians in the detection, segmentation, a | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $450,960 | Grant | Trans-NIH Recovery Act Research Support: This instrumentation request is to purchase a new four-channel NMR console to be used in conjunction with an existing 11.7 T narrow bore super conducting magnet to create a new spectrometer capable of state-of-the-art NMR experiments on solid samples. Thr | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $132,537 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand how vitamin A signaling is modulated by orphan nuclear receptors belonged to the TR2 and TR4 family. Previous studies focused on the repressive mechanisms of TR2 that include i) directly recruiting co-re | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $99,930 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to establish a plasma biomarker panel to verify and monitor initiation and progression of liver cell injury. A recent graduate with a B.S. degree in analytical chemistry/biochemistry will be hired as a Research Associate to | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| FLORIDA STATE UNIVERSITY, THE | $119,668 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the proposed research are: 1, To establish the regulatory relationship between the EGFR and Notch signaling pathways and DG in follicle cell-oocyte communication. 2, To characterize Dystroglycan- and Laminin-mediated cell-cell communi | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $50,930 | Grant | Trans-NIH Recovery Act Research Support: Thyroid hormone (TH) is a key regulator of metabolic homeostasis in humans. It also plays a fundamental role in human development. Thus, an elegant feedback system has developed to tightly control circulating TH levels within a tight range. Central to thi | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | $102,125 | Grant | Trans-NIH Recovery Act Research Support: Predicting Protein Flexibility and Stability (supplement) This research focuses on development of a unique new approach for modeling protein thermodynamic and mechanical properties, which is expected to overcome many of the hurdles limiting the success o | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $89,477 | Grant | Trans-NIH Recovery Act Research Support: This supplement is a request to provide a comprehensive basic imaging analysis software package which can be used by each of the investigators as we begin to extend our collaborative interaction in preparation for our competing renewal application. The s | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $71,000 | Grant | Trans-NIH Recovery Act Research Support: Hyperglycemia and insulin resistance are two major hallmarks of type 2 diabetes. Insulin resistance can cause dysregulation of hepatic gluconeogenesis that leads to the elevated blood glucose levels in diabetics. Pyruvate dehydrogenase kinase 4 (PDK4) pro | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF CONNECTICUT | $7,937,037 | Grant | Trans-NIH Recovery Act Research Support: The University of Connecticut Health Center (UCHC) will renovate 15,480 square feet of space for the Animal Cage Processing Facility (CPF) and surgical suite. UCHC will consolidate and modernize the cage processing and autoclave facilities, properly conf | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| THE VANDERBILT UNIVERSITY | $144,682 | Grant | Trans-NIH Recovery Act Research Support: Metabolic syndrome is devastating our health care system and compromising the quality of life for millions. Understanding the pathogenesis of this condition is paramount to eliminating it. The metabolic syndrome is an epidemic because people have adopted | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $56,537 | Grant | Trans-NIH Recovery Act Research Support: Pancreatic ??cell failure is a critical determinant for the development of diabetes. In spite of the importance of ??cell mass in diabetes, there is a lack in the knowledge base that centers on how ??cells enter the cell cycle and proliferate. Akt is one | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| DUKE UNIVERSITY | $129,897 | Grant | Trans-NIH Recovery Act Research Support: The primay goal of the parent grant is development of innovations in shock wave lithotripsy (SWL) technology. In the past two years, we have completed a series of experiments aiming at comparison of the characteristics of acoustic field, stone comminution | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $428,533 | Grant | Trans-NIH Recovery Act Research Support: Pulmonary arterial hypertension (PAH) is a rare disease that restricts the flow of blood through the pulmonary arteries of the lungs, which leads to right heart failure and death. Epoprostenol, treprostinil, and iloprost are three important drugs that are | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| UNIVERSITY OF NEBRASKA | $998,212 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (11): Regenerative Medicine and specific Challenge Topic 11-AA-102: Roles of Cellular Organelles and the Cytoskeleton in Alcohol-induced Organ Damage. Alcohol abuse and alcohol-induced liver disease are a ma | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF NEBRASKA | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: This University of Nebraska Medical Center proposal describes a plan to renovate the entire interior of the 52,900-square-foot Eppley Cancer Institute building. Opened in 1963, most of the research taking place in the buildingng focused on testing carcinoge... Show more | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The University of Alabama at Birmingham (UAB) has been a clinical site for 7 years in the Urinary Incontinence Treatment Network (UITN), a clinical research network, including nine clinical centers (CC) and a data coordinating center (DCC), established by | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| THE INSTITUTE FOR CANCER RESEARCH | $80,034 | Grant | Trans-NIH Recovery Act Research Support: Title: KINETOCHORE STRUCTURE AND FUNCTION The long term goals of my research program at the Fox Chase Cancer Center are to understand the key mechanical and regulatory events that specify accurate chromosome segregation in human cells. We have focused ou | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $150,417 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We propose to develop and maintain a Data Coordinating Center (DCC) that will provide support for a network of clinical sites studying chronic pediatric liver disease. Specifically we will continue, expand, and merge t | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $149,593 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this application is to ensure the continued success of the Biliary Atresia Research Consortium (BARC) and the Cholestatic Liver Consortium (CLiC). Through a coordinated effort, investigations of eight cholestatic pediatric disorders wi | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| UNIVERSITY OF TEXAS AT AUSTIN | $68,000 | Grant | Trans-NIH Recovery Act Research Support: The Hispanic population, the fastest growing ethnic minority in the US, has a high fertility rate and the potential for a high rate of preterm births (PTB). If the PTB rate continues to rise, it will have devastating effects on children and increase medic | Health and Human Services, Department of / National Institutes of Health | 2/11/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $399,053 | Grant | Trans-NIH Recovery Act Research Support: This is the Final Report. This project is complete. This grant was fully expended. The FFR has been transmitted to the sponsor. Scanned copies of the closeout documents are being emailed to [email protected]. | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF PITTSBURGH THE | $25,000 | Grant | Trans-NIH Recovery Act Research Support: $25,000 supplement to K24 to purchase research van for the transport of study patients | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $94,937 | Grant | Trans-NIH Recovery Act Research Support: Molecular genetics of liver development This administrative supplement is aimed to replace failing equipment used to support our zebrafish colony. PUBLIC HEALTH RELEVANCE It is not known how the endoderm gives rise to the variety of cell types of the dig | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| RNSOLUTIONS, INC. | $217,574 | Contract | : NIH Grant Implementation Support Services for eRA. | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| ZANTECH IT SERVICES, INC. | $827,944 | Contract | : RECOVERY - Service Oriented Architecture (SOA)Technical Support Services | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $235,500 | Grant | Trans-NIH Recovery Act Research Support: Overall, these proposed studies are of importance to understand pancreatic progenitor maintenance and specification, and will directly impact studies of regenerative medicine for diabetes and treatment modalities for pancreatic cancer. They are also rel | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $194,240 | Grant | Trans-NIH Recovery Act Research Support: This is a re-submission application for a request for a new transmission electron microscope (TEM) to replace an existing one that was purchased in 1979. Our current TEM has been operating for 28 years. It is failing and is wholly inadequate to serve the | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| THE GEORGE WASHINGTON UNIVERSITY | $226,738 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the qualitative component for HPTN 064 is to contextualize the behaviors and structural risk factors that put heterosexual women at risk for HIV. These data will complement the quantitative data collected using the computerized, structured | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF OREGON | $177,000 | Grant | Trans-NIH Recovery Act Research Support: We proposed supplemental aims that expanded goals outlined in our last renewal for R01GM058017-11, one of two NIH R01s that fund all the research in our lab. To explore the gene requirements and pathways that regulate and execute cell division, we screen | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF FLORIDA | $179,338 | Grant | Trans-NIH Recovery Act Research Support: Endothelial progenitor cell (EPC) dysfunction may have a key role in the pathogenesis of DR. Two populations of EPCs that arise from cultured mononuclear cells (MNC) are the late outgrowth endothelial cells (OECs), which display a clonal phenotype and bel | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| DJD CONSULTING | $24,000 | Contract | : Technical Review of Assurance and Related Documents | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $123,239 | Grant | Trans-NIH Recovery Act Research Support: Sirtuins are a conserved family (class III) of protein deacetylases that require NAD+ as a co-substrate. There are seven mammalian sirtuins (Sirt1-7) and eleven members of the unrelated class I, II, and IV protein deacetylases. Recent proteomic and direc | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $105,298 | Grant | Trans-NIH Recovery Act Research Support: Some patients respond well to antidepressants, whereas others do not. The biological basis for differences among patients in antidepressant response is poorly understood. Pharmacogenetics seeks DNA markers that can predict medication treatment outcomes. W | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF IOWA, THE | $98,028 | Grant | Trans-NIH Recovery Act Research Support: We have discovered 2 ubiquitin sorting receptors (Ub-sorting receptors) that sort ubiquitinated membrane proteins (Ub-cargo) for degradation in the lysosome. One is the GGA coat protein, which appears to bind Ubcargo at the TGN and incorporate it into ves | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| PC MALL GOV, INC. | $6,041 | Contract | : DELL PRECISION WORKSTATION | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $239,125 | Grant | Trans-NIH Recovery Act Research Support: An adequate number of beta cells are required for production of a sufficient amount of insulin to maintain normoglycemia. Enhancing beta cell proliferation or regeneration can be an effective means to treat type 2 diabetes (T2D). Mutations in the multiple | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| SAINT LOUIS UNIVERSITY | $149,038 | Grant | Trans-NIH Recovery Act Research Support: As an observational study that also serves as a resource for ancillary treatment trials, the multicenter NASH Database study provides a unique opportunity to understand the causes of NASH, identify treatments, and facilitate diagnosis. This supplemen | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF NEBRASKA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: SIG support in next generation DNA | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The Environmental Determinants of Diabetes in the Young (TEDDY), a multicenter prospective cohort study, was initiated in 2003 to identify environmental factors that trigger or protect against the development of islet autoimmunity and type 1 diabetes (T1D | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| NEW YORK UNIVERSITY | $234,337 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides project support, for a technician and for equipment and supplies, to develop a new imaging system, to accelerate the pace of the research. The goal of the research is to employ a new system to study basic properties of regenerat | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | $80,547 | Grant | Trans-NIH Recovery Act Research Support: The database is being assembled and tracking log has been created. Data The database is being assembled and tracking log has been created. MRI data has been obtained from Dr. Heymsfield. MRI data and other relevant data have been obtained from Dr. Gallagh | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| DREXEL UNIVERSITY | $345,938 | Grant | Trans-NIH Recovery Act Research Support: This is an application to develop an orally available imino sugar for the treatment of flaviviruses infections of bioterror concern, with a focus upon West Nile Encephalitis virus (WNEV) and Dengue Viruses (DV). Our lead compound, the imino sugar, N, -non | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF CHICAGO, THE | $92,046 | Grant | Trans-NIH Recovery Act Research Support: Modern drugs are highly functionalized molecules, and often these molecules are chiral. The most promising solution for production of these molecules has relied on an asymmetric catalytic process, especially catalytic asymmetric oxidation, which can intro | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF WASHINGTON | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Impaired mobility in Parkinson's disease (PD) is associated with decreased independence, reduced quality of life, and increased risk for falls, leading people with PD to identify mobility limitations as one of the worst aspects of the disease. We have an | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| UNIVERSITY OF CONNECTICUT | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Precise control of biosynthesis, storage and secretion of bioactive peptides requires coordinate control of many cellular processes. Genetically engineered mice were used to determine that Kalirin, a large protein with many interactions, plays an essentia | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF MASSACHUSETTS | $92,845 | Grant | Trans-NIH Recovery Act Research Support: Our current work under this grant has focused on understanding the function of one of the FYVE-domain containing proteins, WDFY2 in cultured cells. We identified this previously uncharacterized protein, which contains a FYVE domain embedded within WD40 re | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF ARIZONA | $186,349 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of this administrative supplement is to describe patterns of genetic variation across the genome in wild house mice (Mus musculus). These data will be used to address questions concerning the distribution of variation among subspecies, th | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| NEWPORT CORPORATION | $284,375 | Contract | : SPFIRE PRO_F1KXPPhilip Anfinrud Bldg 5/134 | Health and Human Services, Department of / National Institutes of Health | 11/12/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $116,991 | Grant | Trans-NIH Recovery Act Research Support: DNA replication is a crucial step in the eukaryotic cell cycle. Activation of replication origins in early S phase requires the assembly of a pre-replication complex that is subsequently modulated into a pre-initiation complex and finally into a fully act | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $300,329 | Grant | Trans-NIH Recovery Act Research Support: With the NIH-support parent grant (P30 DK040561), we proposed an established instituional resource, the Harvard Clinical Nutrition Reasearch Center (HCNRC), principally based at the Massachusetts General Hospital of the Harvard Medical School in close col | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| UNIVERSITY OF PITTSBURGH THE | $134,338 | Grant | Trans-NIH Recovery Act Research Support: The focus of this award is on generation of new knowledge that will lead to novel approaches to diseases. During growth factor-induced migration of adherent cells, which is critical to wound repair and tissue regeneration, adhesions to the underlying sub | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $66,540 | Grant | Trans-NIH Recovery Act Research Support: Comparative interaction mapping resolves protein complexes and signaling pathways on the basis of their conservation across different species or types of interaction network. It is an emerging methodology which, like comparative genomics, provides a power | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $78,860 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand the molecular basis of inherited metabolic diseases caused by inborn errors of macromolecular catalytic machines. The model system under study is a family of highly conserved human alpha-ketoacid dehydro | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| THOMAS JEFFERSON UNIVERSITY | $231,680 | Grant | Trans-NIH Recovery Act Research Support: Liver injury due to prescription and non-prescription medication use is an important public health problem. Drug-induced liver injury (DILI) is the most common reason for adverse actions taken on drugs by the Food and Drug Administration. Detection of DIL | Health and Human Services, Department of / National Institutes of Health | 3/29/2009 |
| MICHIGAN STATE UNIVERSITY | $7,479,525 | Grant | National Center for Research Resources, Recovery Act Construction Support: As our nation struggles with health care challenges from an aging population, to a shortage of nurses, there is an increasing need for nurse scientists to provide leadership in the translation of successful research into clininical practice. The land-grant ... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| CALDERA PHARMACEUTICALS, INC. | $178,915 | Grant | Trans-NIH Recovery Act Research Support: Caldera Pharmaceuticals will complete the necessary steps to commercialize its XRflo system. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF PITTSBURGH THE | $92,001 | Grant | Trans-NIH Recovery Act Research Support: The Nikon Swept Field Confocal microscope system will provide widefield microscope capacity with greater speed and higher resolution than other available systems. This means that we will be able to capture the most rapid processes in delineating disease | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| THOMAS JEFFERSON UNIVERSITY | $174,955 | Grant | Trans-NIH Recovery Act Research Support: The importance of imaging small animals in basic and translational biomedical research, with such modalities as PET, SPECT, CT, optical, ultrasound, and MRI, cannot be over- emphasized. The ability to image small animals without sacrificing them, allows i | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $14,590,939 | Grant | National Center for Research Resources, Recovery Act Construction Support: The West Virginia University Robert C. Byrd Health Science Center is seeking to expand support of its biomedical research activity and infrastructure by constructing a new animal facility addition to the current vivarium. Thihis proposal requests funding f... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| BIOANALYTICAL SYSTEMS, INC. | $17,021 | Contract | : Ternary Gradient System | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| UNIVERSITY OF IOWA, THE | $100,651 | Grant | Trans-NIH Recovery Act Research Support: Genetic pathways that promote cell-survival during development are poorly defined, yet represent potential targets for anti-cancer drugs. The genes that promote survival of melanocytes, in particular those that operate independently of the well-characteri | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| EMORY UNIVERSITY | $154,463 | Grant | Trans-NIH Recovery Act Research Support: BASES OF PATHOPHYSIOLOGY IN GALACTOSEMIA Profound impairment of galactose-1-phosphate uridylyltransferase (GALT) results in the inborn error of metabolism classic galactosemia. Although the acute and potentially lethal sequelae of this disorder can be res | Health and Human Services, Department of / National Institutes of Health | 1/30/2010 |
| UNIVERSITY OF FLORIDA | $113,146 | Grant | Trans-NIH Recovery Act Research Support: Mitochondria (mt) play key roles in cellular energy production and cell death. Beta cell function is tightly linked to mitochondria, as both insulin synthesis and glucose stimulated insulin secretion require mitochondrial ATP production. In this context, | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $194,416 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Therapeutic agents such as small interfering silencing ribonucleic acids (siRNAs), ribozymes, and anti-sense ribonucleic acids (RNAs) show significant potential in new molecular approaches to down-regulate specific gen | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| TRUSTEES OF BOSTON UNIVERSITY | $100,001 | Grant | Trans-NIH Recovery Act Research Support: Administration Supplement funds are requested to follow up on exciting new research progress under grant DK33765, 'Cytochrome P450-Endogenous Substrate Metabolism'. Specifically, the supplemental funding will be used to accelerate the pace of scientific d | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $98,350 | Grant | Trans-NIH Recovery Act Research Support: The scientific relevance of this proposal derives from the potential clarification of the phenotype-genotype relationship within the most common genetic form of severe obesity in humnas. Relevance of the proposal to the intent of the Recovery Act stems fr | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $100,141 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to further studies that examine the effects of Roux-en-Y gastric bypass surgery on insulin secretion and sensitivity in individuals with Type 2 diabetes. The main objective is to compare outcomes of surgery with that of a | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| CORNELL UNIVERSITY, INC | $468,630 | Grant | Trans-NIH Recovery Act Research Support: In this proposal, funds are requested to acquire a sensitive modern X-band CW-ESR spectrometer, which will support biomedical research at Cornell (Ithaca) and Weill Medical College of Cornell University. This will replace a 25 years old ESR spectrometer t | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $98,763 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this research is to determine the molecular basis of membrane traffic in mammalian cells. The focus is on mannose 6-phosphate receptors (MPRs) that deliver newly synthesized lysosomal enzymes from the Golgi to pre-lysosomes, and then | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $75,913 | Grant | Trans-NIH Recovery Act Research Support: Duplex DNA is copied continuously on one strand (leading), but discontinuously on the other (lagging) strand to form short segments called Okazaki fragments. Thus, lagging strand synthesis is a much more complex process. Failure to properly synthesize and | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $79,326 | Grant | Trans-NIH Recovery Act Research Support: The problem of progression of renal fibrosis leading to endstage renal failure remains unresolved. The progressive tubulointerstitial lesions are characterized by tubuloepithelial damage and atrophy, peritubular capillary rarefication and interstitial fib | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| UNIVERSITY OF MIAMI | $129,787 | Grant | Trans-NIH Recovery Act Research Support: Restoring blood flow to the site of injured tissue is a prerequisite for mounting a successful repair response. It is now well established that the sources of endothelial cells which build newly-formed blood vessels come from both pre-existing vessels (an | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $95,687 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to support the training of a pre-doctoral graduate student who is Mexican-American. The objective is to provide the student with educational opportunities and experience that will facilitate the development of the student' | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| ALLEN INSTITUTE FOR BRAIN SCIENCE, THE | $16,210,005 | Grant | Trans-NIH Recovery Act Research Support: The goal of the current Grand Opportunity is to create a unique, multimodal transcriptional atlas of the pre- and postnatal developing human brain. This new and unique data-rich resource will integrate transcriptomic, cellular resolution histology and im | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Treatment options for GI motility disorders are limited, reflecting the need for new model systems and for identification of new, effective drug targets. The specific objective of this AREA proposal is to establish the zebrafish as a model system to study | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $99,340 | Grant | Trans-NIH Recovery Act Research Support: Kidney injury molecule-1 (KIM-1) is strongly upregulated in proximal tubular epithelial cells in various states characterized by epithelial cell dedifferentiation: ischemia, toxic renal injury, polycystic kidney disease and renal cell carcinoma. It is upr | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $105,653 | Grant | Trans-NIH Recovery Act Research Support: The essential role of vitamin B12 (Cbl) in recycling folate and thereby in DMA synthesis and single carbon metabolism and in the generation of methionine, the precursor for biological methylations is indicated by the clinical presentation of megaloblastic | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $99,600 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Erectile dysfunction (ED) is increasing in prevalence with the ageing of society and with greater numbers of patients suffering from diabetes, which are risk factors for its development. The impact of ED on quality of | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $384,820 | Grant | Trans-NIH Recovery Act Research Support: The signal transduction events within endothelial cells (ECs) or macrophages which encode the complex cascade of events required for angiogenesis are poorly understood. The objective of this proposal is to gain insight into the regulatory network in ECs o | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| IRON BRICK ASSOCIATES, LLC | $865,607 | Contract | : Recovery- Storage System for NIH Biowulf Cluster | Health and Human Services, Department of / National Institutes of Health | 5/03/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $90,772 | Grant | Trans-NIH Recovery Act Research Support: Supplementary funds are requested to purchase three items of equipment that are needed for research supported by this grant. Over the 24 years of funding of this grant there has been great difficulty in maintaining our equipment needs. One item requested | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Shared instrumentation grant to establish next-generation sequencing technology at The Research Institute at Nationwide Children's Hospital | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $12,970,423 | Grant | National Center for Research Resources, Recovery Act Construction Support: NIH-funded research has been increasing at a dramatic pace on the University of California, Irvine (UCI) campus, and is enabling breakthroughs in a number of fields, in particular the emerging area of stem cell and regenerativive medicine research. This AR... Show more | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $14,228,198 | Grant | National Center for Research Resources, Recovery Act Construction Support: This application from California National Primate Research Center (CNPRC) located on the University of California (UC), Davis campus seeks to obtain federal funding through the American Recovery Act Limited Competition Extramumural Research Facility Improve... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $257,642 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $32,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Metabolic syndrome is emerging as a global epidemic. The profound metabolic dysregulation in this syndrome is typically manifested by clustering of several disorders, including obesity, type 2 diabetes, and dyslipidemi | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $81,673 | Grant | Trans-NIH Recovery Act Research Support: Microtubules are rigid polymers that serve a critical role in cellular architecture as structural buttresses and tracks for motor proteins. The molecular mechanisms of microtubule polymerization dynamics are not well understood, and this confounds rigorou | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $159,408 | Grant | Trans-NIH Recovery Act Research Support: The proposed research will accelerate the development of new classes of therapeutics for CNS and eye diseases, as identified in the parent project (EY018479). Measured against a quarterly progress schedule, this concerted and dedicated effort by 1 new res | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF HOUSTON SYSTEM | $450,000 | Grant | Trans-NIH Recovery Act Research Support: Bacterial resistance to antibiotics is rising at an alarming rate. Of particular concern is the prevalence of multidrug resistant Gram-negative bacteria (e.g., Pseudomonas aeruginosa), for which all available first-line antibiotics are ineffective. The | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| SOUTH DAKOTA STATE UNIVERSITY | $107,564 | Grant | Trans-NIH Recovery Act Research Support: The novel contributions under the requested supplement fall into third major areas. First, we will be able to develop a more sophisticated framework for system design and evaluation that was envisioned under the original application. In particular, we wil | Health and Human Services, Department of / National Institutes of Health | 4/05/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $164,000 | Grant | Trans-NIH Recovery Act Research Support: The project funded by this ARRA supplement will advance our mechanistic understanding of the Biogenesis of Exosomes, small vesicles that are secreted by human cells, play important roles in immune signaling and development, and are implicated in cancers, | Health and Human Services, Department of / National Institutes of Health | 3/09/2010 |
| UNIVERSITY OF ARIZONA | $73,945 | Grant | Trans-NIH Recovery Act Research Support: Protein aggregation resulting from stress, disease or mutation poses a major threat to all cells. Consequently, cells have developed mechanisms of ?protein quality control? involving specific proteases and molecular chaperones that prevent or resolve pro | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $64,230 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to investigate the signaling pathways controlled by mTOR, a highly conserved Ser-Thr phosphatidylinositol 3-kinase-related protein kinase. We recently demonstrated that the mTOR-mediated phosphorylation of raptor is required fo | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| UNIVERSITY OF THE SCIENCES IN PHILADELPHIA | $25,000 | Grant | Trans-NIH Recovery Act Research Support: The National Institutes of Health hereby awards a grant in the amount of $25000 to USP in support of Dr. Li's research. The award is pursuant to the authority of 42 USC 241 42 CFR 52 and is subject to the requirements of this statute and regulation and of | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| RENSSELAER POLYTECHNIC INSTITUTE | $128,845 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to delinate the complete catalytic mechanisms of protein splicing by applying solution NMR in an interdisciplinary approach for studying enzyme catalysis, structure, dynamics and function. | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| WASHINGTON UNIVERSITY, THE | $99,895 | Grant | Trans-NIH Recovery Act Research Support: Development in all living organisms is controlled by the precise arrangement of molecular cues. For proper development, these cues must be present at specific concentrations and in defined locations. Traditional biological approaches to studying developme | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF WASHINGTON | $98,719 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement application is to investigate the structure /function relationships of the beta globin locus control region by introducing mutations in the endogenous beta globin LCR of human ES cells and assessing effects on gl | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| CLAREMONT GRADUATE UNIVERSITY | $107,803 | Grant | Trans-NIH Recovery Act Research Support: Chronic non communicable disease accounts for 60% of the world's mortality and morbidity. Training programs in global public health, specific to the NCD epidemic are vital especially in developing nations that until recently have dealt primarily with infe | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $86,611 | Grant | Trans-NIH Recovery Act Research Support: Adolescents with bipolar disorder (BP) have high rates of recurrence, suicide attempts, functional impairment, and service utilization even when aggressively treated with mood stabilizers and antipsychotics. Despite its considerable public health risk, th | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $111,050 | Grant | Trans-NIH Recovery Act Research Support: The broad, long-term objective of this proposal is to understand the molecular signaling events during AIDS neuropathogenesis and blood-brain barrier (BBS) disruption. Encephalitis, characterized by perivascular cuffing of infected monocyte-derived macrop | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Funds are requested to upgrade an existing commercial Bruker Elexsys 500 continuous wave EPR spectrometer to add pulse capability. The upgraded instrument will be a highly versatile EPR instrument that will be capable of a broad range of pulse experiments | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| PRICEWATERHOUSECOOPERS LLP | $454,786 | Contract | : The purpose of this statement of work is to assist NIH OFM management in the performing the procedures necessary to meet at minimum the requirements included in Department Guidance Manual for OMB Circular A-123 Assessment. The objective of which is to con | Health and Human Services, Department of / National Institutes of Health | 1/06/2010 |
| UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION | $94,775 | Grant | Trans-NIH Recovery Act Research Support: A central goal of our current North San Diego Bridges to the Future program is to enhance the academic achievement of underrepresented science majors. Our program does this by providing Supplemental Instruction (SI) for gatekeeper courses in math and the | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| RESEARCH TRIANGLE INSTITUTE | $962,616 | Contract | : RTI is to create a public query tool (application) to enhance the research capability of the the NIDDK data repository, and will modify the NIDDK CDR portal . | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $45,603 | Grant | Trans-NIH Recovery Act Research Support: Summer research project has been planned and was work on with HR for some period of time and 2 students will officially began work on July 5, 2010. Specifically, this supplement will allow us to support summer research opportunities to a TTUHSC medical s | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The objectives of this research plan are to determine the mechanism by which SFA activate PP2A in hepatocytes and the mechanism by which events downstream of PP2A cause lipotoxic cell death. This is the final report for this award. The FFR was submitted | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| MCCONNELL GROUP, INC. THE | $179,000 | Contract | : Purchase of a bioanalytical equipment, a Genome Analyzer. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $66,473 | Grant | Trans-NIH Recovery Act Research Support: Delayed parenchymal (hepatocellular) killing occurs in liver grafts that begins after about 4 h and can lead to graft dysfunction and failure. The mechanisms of delayed parenchymal cell injury develops remain poorly understood. Our preliminary experiments | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| UNIVERSITY OF KENTUCKY | $438,780 | Grant | Trans-NIH Recovery Act Research Support: Challenge Area - (11) Regenerative Medicine Specific challenge topic - 11-DK-101 Promote regeneration and repair in the digestive system, liver, pancrease, kidneys, hematologic, and urological system. 3. Project Title: Slit2-mediated expansion of primitiv | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| SOUTHERN UNIVERSITY AND ANM COLLEGE SYSTEM | $144,570 | Grant | Trans-NIH Recovery Act Research Support: The SCORE program at Southern University at Baton Rouge (SUBR) was reestablished in 2006 with the long-term goal to enhance and expand the overall biomedical research capability of the university. The SUBR SCORE program continues to enhance the research a | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF MARYLAND | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This is a 5-year training plan for a mentored physician scientist in Gastroenterology and Hepatology. The Principal Investigator is a junior faculty member in the Division of Gastroenterology and Hepatology at University of Maryland School of Medicine (UM | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF ROCHESTER | $39,270 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the parent proposal is to elucidate the mechanism through which androgen receptor (AR) regulates B lymphopoiesis. The original proposed studies will test the hypothesis that AR up-regulates proliferation and resistance to apoptos | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| MAYO CLINIC | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The requested funds will be used to secure employment for a post-doctoral research scientist and provide resources to accelerate our research mission of developing a cellbased liver support device for treatment of acute liver failure. Liver failure is a s | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| UNIVERSITY OF FLORIDA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The University of Florida contributes substantially to the local and regional economy. In 2008, UF created 2,525 jobs and recent studies have shown that UF contributes nearly $6 billion annually to Florida's economy. The university employs about 34,000 pe | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $119,217 | Grant | Trans-NIH Recovery Act Research Support: The aims of the supplement are to support the goals of the parent grant by 1) increasing the efficiency of creating transgenic lines of Drosophila melanogaster expressing myosin heavy chain, 2) improving the expression of levels of transgenic myosin genes | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| TRUSTEES OF THE SMITH COLLEGE, THE | $367,879 | Grant | Trans-NIH Recovery Act Research Support: Ischemic injury is a debilitating outcome of natural illness and is a complication of commonly performed medical procedures. Given the prevalence and severity of outcomes in ischemic injury, there is significant interest in developing better pharmacologic | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| THE GEORGE WASHINGTON UNIVERSITY | $15,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: Title: Space Renovation for New Research Center for the Neglected Diseases of Poverty - The George Washington University ('GWU') is to renovate approximately 25,400 net square feet of obsolete space to create a centrally locatated modern research complex fo... Show more | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| ST LUKE'S-ROOSEVELT HOSPITAL CENTER | $11,262 | Contract | : As defined in the project abstract | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $288,521 | Grant | Trans-NIH Recovery Act Research Support: This is a Competitive Revision for GM50403 of Notice Number (NOT-OD-09-058), and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The state of Michigan has been particularly hard hit by the economic | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $196,041 | Grant | Trans-NIH Recovery Act Research Support: Proopiomelanocortin (POMC) neurons within the arcuate nucleus are a critical component of the hypothalamic neural circuits that regulate whole body energy balance. However, individual POMC neurons exhibit significant heterogeneity in their repertoire of | Health and Human Services, Department of / National Institutes of Health | 1/05/2010 |
| PURDUE UNIVERSITY | $495,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The Purdue Flow Cytometry and Cell Separation Facility of the Bindley Biosciences Center in Discovery Park at Purdue University proposes to purchase a new LEAP (Laser Enabled Analysis and Processing) (Cyntellect, Inc., | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| WORLD WIDE TECHNOLOGY, INC. | $376,275 | Contract | : ADP Support Equipment | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF BOSTON UNIVERSITY | $406,681 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06) Enabling Technologies and specific Challenge Topic, 06-DK-104 Enabling technology for the prevention and treatment of diseases within the NIDDK mission. . In particular, it addresses the three priority | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $126,475 | Grant | Trans-NIH Recovery Act Research Support: The zebrafish is an ideal model system in which to study the effects of genetic mutations on eye development and function. Its retina contains four types of cones as well as abundant rods, and the animals are highly responsive visually, enabling the analy | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $114,516 | Grant | Trans-NIH Recovery Act Research Support: Stem cells, and how they are controled is a key question in biomedical research. The protein, Zfh1, controls adult stem cells in the Drosophila testis. This supplement has accelerated our ability to identify the suite of Zfh1 target genes that control sel | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $37,000 | Grant | Trans-NIH Recovery Act Research Support: We requested funds to increase the tempo of our research progress. Funds were provided to (a) update an stopped flow fluorometer that used a computer platform that was no longer supported, and (b) increase the rate at which we can produce recombinant pro | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $2,039,261 | Grant | National Center for Research Resources, Recovery Act Construction Support: In the last decade the Cleveland Clinic Taussig Cancer Institute (TCI) has demonstrated tremendous growth in terms of cancer care, clinical trials and translational cancer research. This expansion was initially enabled by a momove into a new building in 200... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $612,145 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The exquisite alignment of projections from the two eyes in central visual structures is fundamental for a precise representation of the visual world. We have discovered that the transmembrane protein Ten_m3 is a criti | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Neural crest stem cells are involved in human illnesses including tumors and craniofacial and heart malformations. They generate most of the cells of the peripheral nervous system, craniofacial bone and cartilage, cells of the outflow tract of the heart a | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| THE VANDERBILT UNIVERSITY | $129,600 | Grant | Trans-NIH Recovery Act Research Support: This application is a response to NOT-DK-04-501 and a letter RFA for Vanderbilt University to continue to serve as the Coordinating Center (CC) for the Beta Cell Biology Consortium (BCBC), a team science initiative that has been in existence since Septemb | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF UTAH, THE | $44,897 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The fruit fly Drosophila melanogaster has 18 nuclear receptor (NR) genes, significantly fewer than the 48 genes found in humans, spanning all vertebrate NR subclasses and encoding orthologs of key human receptors, incl | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $131,824 | Grant | Trans-NIH Recovery Act Research Support: In the NIH-supported core projects conducted by the eight co-investigators of this proposal, Circular Dichroism (CD) spectropolarimetry provides a unique window into dynamic aspects of protein conformation and unfolding, conformational transitions accompa | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| THE VANDERBILT UNIVERSITY | $95,263 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to fund equipment infrastructure upgrade to allow uninterrupted progress of proposed study in the parent grant. The goal of this study is to understand how the subcellular localization and activation of WASP is regulated | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| PURDUE UNIVERSITY | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The active form of vitamin D (1,25(OH)2D) regulates events in bone, kidney and intestine to control whole body Ca metabolism and influence the development of osteroporosis. Several lines of evidence suggest that the role of Ca absorption in osteoporosis d | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| JOHNS HOPKINS BAYVIEW MEDICAL CENTER, INC | $7,000,028 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We request funds to develop a Translational Molecular Imaging Center (TMIC) on the Johns Hopkins Bayview (JHB) medical campus. There is currently no such center at the Johns Hopkins Medical Institutions (JHMI) and few, | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| BAYLOR COLLEGE OF MEDICINE | $149,952 | Grant | Trans-NIH Recovery Act Research Support: The Liver Center at Texas Children's Hospital/Baylor College of Medicine (TCH/BCM) has been an active participant in BARC and CLiC, and is excited by the opportunity to continue participation. The overarching aims of this Center are to help advance the cl | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| PRICEWATERHOUSECOOPERS LLP | $8,619,910 | Contract | : PwC will assist the NIH Business System (NBS) Program to: G?? Support funds control at the Anti-Deficiency Act (ADA) Level, G?? Integrate grants and financial management systems, G?? Integrate the payment management system (PMS) and financial management | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $419,168 | Grant | Trans-NIH Recovery Act Research Support: We propose to expand and maintain the Adult to Adult Living Donor Liver Transplantation Cohort Study Data Coordinating Center (A2ALL DCC) that will support a consortium of transplant centers in conducting continued observational and interventional researc | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $206,532 | Grant | Trans-NIH Recovery Act Research Support: Award Description: PROJECT SUMMARY: About 1-2% of American children have abnormal binocular vision, characterized by misalignment of the eyes. This condition is called strabismus. The goal of this project is to understand how the brain compensates for str | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| UNIVERSITY OF ILLINOIS | $47,361 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of this project are to couple our molecular modeling capabilities with new methodologies for encapsulating membrane proteins in soluble Nanodisc structures and obtaining precise three-dimensional structures by solid-state NMR (SSNMR) to | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |