Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| LUDWIG INSTITUTE FOR CANCER RESEARCH LTD | $79,750 | Grant | Trans-NIH Recovery Act Research Support: Eukaryotic chromosome segregation requires kinetochores, organelles that assemble on condensing chromosomes to form dynamic attachment sites for spindle microtubules. Errors in kinetochore function contribute to chromosomal instability during tumorigenesi | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Funding is requested for a 500 MHz NMR spectrometer to replace a 15 year old, outdated 500 MHz NMR. The new instrument is necessary for the solution-state NMR needs of the NIH user group at Columbia University that consists of 10 faculty who in aggregate | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $14,999,999 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Memorial Sloan-Kettering Cancer Center (MSKCC) is seeking $15 M of federal support for a $19.74 M project to expand and equip an existing state-of-the-art barrier vivarium. As a result of weakening economic conditions, MSKSKCC was forced to cease constr... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| ARCHITECTS DESIGN GROUP PC | $427,609 | Contract | : Architect & Engineering Services - NIH/Rocky Mountain Laboratories Building 7 Construction Contract Administration Services | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $492,101 | Grant | Trans-NIH Recovery Act Research Support: Crystallographic experiments require a reliable in-house X-ray facility for high throughput screening of crystal quality and cryoprotection conditions, and for high resolution data collection from many hundreds of protein crystals. The new equipment is re | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| CEDARS-SINAI MEDICAL CENTER | $9,552,872 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cedars-Sinai Medical Center has recently completed a $15 million seismic upgrade to the SS Building (SSB), currently a mixed-use facility. We now request the NIH to partner with us to redirect space in SSB for translat | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $29,000 | Grant | Trans-NIH Recovery Act Research Support: -80 C freezer to safely store the tissue and blood samples obtained from the mice used in the experiments for Aim1 and Aim 2, protein samples that are obtained from the cellular experiments performed in Aim 3, adenoviruses that are produced for creating | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $195,800 | Grant | Trans-NIH Recovery Act Research Support: The neurotransmitter dopamine is pivotal in decision making, habit and motor learning as well as in drug abuse, schizophrenia, attention deficit hyperactive disorder (ADHD), and Parkinson's disease. This joint effort from three NIH-funded laboratories exp | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $9,989,340 | Grant | National Center for Research Resources, Recovery Act Construction Support: This application for NIH ARRA funds seeks to expand, improve, and consolidate space for laboratories, lab support, training, and related administration on the entire 23rd floor of the Annenberg Tower (Ann-23). The proposed prproject will support translatio... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The morbidity of inflammatory bowel disease (IBD) stems from its effect on electrolytes, nutrients and fluid absorption; thus, patients with IBD sustain malabsorption and diarrhea with attendant malnutrition and weight loss. It has long beenheld that onc | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $382,500 | Grant | Trans-NIH Recovery Act Research Support: Herpes simplex virus (HSV-1) is a major cause of vision loss worldwide. Our long-term goal is to develop an effective vaccine against ocular herpes. Natural HSV-1 immunity does not efficiently protect against recurrent infections or new infections, sugg | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $102,400 | Grant | Trans-NIH Recovery Act Research Support: We are proposing global proteomics discovery studies using serum samples obtained from the prospective Drug-Induced Liver Injury Network (DILIN) clinical trial funded by the NIH. We hypothesize that discovery and validation of serum biomarkers will accura | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| MCLAUGHLIN RESEARCH INSTITUTE FOR BIOMEDICAL SCIENCES, INC. | $148,992 | Grant | Trans-NIH Recovery Act Research Support: The award grants McLaughlin Research Institute for Biomedical Sciences, Inc. funds with which to replace an aging and obsolete Molecular Dynamics Phosphorimager SI with a new General Electric Typhoon 9410 Variable Mode Imager. The acquisition of the GE Ty | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| UNIVERSITY OF TENNESSEE | $59,460 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research project is to define genetic networks controlling susceptibility and resistance of retinal ganglion cells to optic nerve damage and to characterize the early molecular signatures associated with these changes. Our worki | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| DELOITTE & TOUCHE L.L.P. | $61,989 | Contract | : This contract was awarded to Deloitte to enhance OHR's Workflow Information and Tracking System (WiTS) to capture and report on the ARRA data. NIH-OHR established the WiTS system to improve its HR services through standardized and streamlined business p | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $42,152 | Grant | Trans-NIH Recovery Act Research Support: While a role for adenosine monophosphate activated protein kinase (AMPK) in regulating body energy balance via effects in non-adipose tissues has gained acceptance, little is known about the biological function of AMPK in white and brown adipose tissues. | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| EAST TENNESSEE STATE UNIVERSITY | $6,729 | Grant | Trans-NIH Recovery Act Research Support: Life style alterations can be powerful deterrents to developing type 2 diabetes and are cornerstones of the treatment of this condition. Both aerobic and resistance exercise improve diabetes blood glucose control and insulin resistance. These two types of | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $77,817 | Grant | Trans-NIH Recovery Act Research Support: Web-based technology is increasingly being utilized in human subject research given its cost-effectiveness, efficiency, accuracy, and convenience. Web-based technology is also an innovative approach to proactively address participant retention in longitud | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| CARL ZEISS MICROIMAGING, INC. | $276,115 | Contract | : Laboratory Equipment | Health and Human Services, Department of / National Institutes of Health | 3/03/2010 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $109,981 | Grant | Trans-NIH Recovery Act Research Support: In this application, we propose to enroll patients with inborn errors of bile acid metabolism into investigative protocols approved by the consortium. These inborn errors present with cholestasis in children and lead to progressive liver disease if untrea | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $79,969 | Grant | Trans-NIH Recovery Act Research Support: This award is an administrative supplement to grant DK080351. The supplement is designed to acquire 3 instruments that will enhance the performance of the scientific program proposed in the parent grant. | Health and Human Services, Department of / National Institutes of Health | 2/15/2010 |
| PROMEGA CORPORATION | $18,961 | Contract | : purchase of Glomax luminometer | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| THE VANDERBILT UNIVERSITY | $8,675,794 | Grant | Trans-NIH Recovery Act Research Support: VANTAGE (VANderbilt Technologies for Advanced Genomics) represents a logical next step in advancing a highly successful institutional policy of shared resource management coupled to an increasingly robust scientific capability for translational research a | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF TOLEDO, THE | $409,200 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): To understand the interactions between the Mycobacterium tuberculosis (mtb) antigen 85 enzymes and their substrates, identify components of each enzyme that lead to differences in substrate specificity, identify inhibi | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $45,500 | Grant | Trans-NIH Recovery Act Research Support: ATP-dependent chromatin-remodeling complexes, such as the evolutionarily-conserved INO80 complex, are essential for the maintenance of genomic integrity. However, the diverse INO80 chromatin-modifying activities that are necessary for proper DNA damage re | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| EMORY UNIVERSITY | $14,868,223 | Grant | National Center for Research Resources, Recovery Act Construction Support: The goal of this project is the construction of a new dual function 19,800 sq ft building devoted to NHP research in two of the most rapidly growing areas of the Yerkes research portfolio that align with national health prioririties -infectious disease and ... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $26,000 | Grant | Trans-NIH Recovery Act Research Support: Feeding behavior is critical for animal survival, and is also a fundamental aspect of energy homeostasis. The growing incidence of eating disorders and their associated health costs have led to intensive research efforts directed to understand the mechani | Health and Human Services, Department of / National Institutes of Health | 2/08/2010 |
| UNIVERSITY OF WASHINGTON | $62,553 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement to the parent grant entitled, Genetic and Molecular Basis of Congenital Contractures is to explore the mechanism(s) by which mutations in genes that encode contractile proteins cause multiple congenital contractu | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $12,998,888 | Grant | National Center for Research Resources, Recovery Act Construction Support: The University of Pennsylvania proposes to catalyze the formation of the PENN Center for Chronobiology through construction of 46,204 gross square feet (gsf) of contiguous space in the Translational Research Building, thereby y uniting basic scientists stud... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Cyclic 3',5'-adenosine monophosphate (cAMP), the classical second messenger, regulates many diverse cellular functions. Although much has been learned about cAMP and cAMP-dependent protein kinase (PKA), there are still large gaps in our understa | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $99,783 | Grant | Trans-NIH Recovery Act Research Support: In our supplement to NIH R01DK076602, we are examining the functional properties of CAstration-Resistant Nkx3.1-expressing cells (CARNs), which are rare luminal epithelial cells in the androgen-deprived mouse prostate that are multipotent and can self-re | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| THERMO ELECTRON NORTH AMERICA LLC | $959,620 | Contract | : Laboratory Equipment | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF PITTSBURGH THE | $36,453 | Grant | Trans-NIH Recovery Act Research Support: The major piece of equipment (the bomb calorimeter) purchased under this ARRA award will be used to assess the energy content of fecal matter from mice, a critical component of energy homeostasis. The other equipment (Harvard pumps) is used to deliver r | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| NEW YORK UNIVERSITY (INC) | $11,718 | Grant | Trans-NIH Recovery Act Research Support: NIH identified five gateway areas to increasing public trust in clinical research: building trust through community partnerships; building relationships with patients; building partnerships with community providers; building trust in scientists; and build | Health and Human Services, Department of / National Institutes of Health | 2/08/2010 |
| VICON MOTION SYSTEMS, INC. | $143,150 | Contract | : Award of $143,150.00 was used to puchase a Vicon System and its related components and software to capture medical, dental, and scientific data for the use in NIA IRP CRB LSS longitudinal studies. | Health and Human Services, Department of / National Institutes of Health | 7/01/2009 |
| EMORY UNIVERSITY | $77,500 | Grant | Trans-NIH Recovery Act Research Support: The pathogenesis of sickle cell nephropathy. Sickle cell nephropathy is a common complication of sickle cell disease that affects both children and adults, and may lead to kidney failure. The mechanisms that cause kidney damage in sickle cell disease are | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $450,000 | Grant | Trans-NIH Recovery Act Research Support: We propose to develop an approach for the identification of cis-regulatory sequence elements in mammalian genomes. Our approach calls for simultaneous expression profiling and TF-binding-location analysis under multiple time points and conditions relevant | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $93,656 | Grant | Trans-NIH Recovery Act Research Support: One of insulin's major biologic effects is stimulation of glucose transport, and detailed knowledge of the molecular events which mediate this bioeffect will lead to improved understanding of mechanisms of insulin action as well as disease states characte | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| BECTON, DICKINSON AND COMPANY | $307,872 | Contract | : Purchase of Flow Cytometer | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| BECKMAN COULTER, INC. | $55,852 | Contract | : SW--42 Ti Swinging Bucket, Titanium Rotor Package, Item#331336;Type 70Ti Fixed Angle, Titanium Rotor Assembly,Item#337922; SW-32 Ti Swinging Bucket, Titanium Head/Titanium Buckets, Item#369650; SW-55Ti Swinging Bucket, Titanium Rotor Package, Item#342196 | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| UNIVERSITY OF CHICAGO, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The bulk of filtered CI is reabsorbed in the proximal tubule by passive and active pathways. SLC26A6 has recently emerged as the likely key transporter that accounts for reabsorption of this active component, and thus contributes significantly to proximal | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| LEGACY EMANUEL HOSPITAL & HEALTH CENTER | $281,936 | Grant | Trans-NIH Recovery Act Research Support: Ischemic stroke is a leading course of mortality and morbidity, and the most common reason for long-term disabilities. Unfortunately there is still no effective treatment for stroke patients. Our recent studies in neuronal cell culture have demonstrated | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| WASHINGTON UNIVERSITY, THE | $59,000 | Grant | Trans-NIH Recovery Act Research Support: DNA helicases are ATP-dependent motor proteins that unwind duplex DNA to form the single stranded (ss) DNA intermediates required for DNA metabolism in all organisms. We are studying the kinetic mechanisms of DNA unwinding and DNA translocation of three n | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $123,480 | Grant | Trans-NIH Recovery Act Research Support: Several messages can use an alternative mechanism of initiating translation when cap-dependent translation is down regulated. These messages contain internal ribosome entry sites within their 5'untranslated region. The mRNAs that contain IRESs encode pr | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Objectives: The objective of this study is to develop and pilot test a list of candidate quality-of-care indicators for women with (OAB). The study will also identify variation in care between primary care clinics in the VA healthcare system and at UCLA | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $491,996 | Grant | Trans-NIH Recovery Act Research Support: Measurement of the individual factors that drive energy balance and tissue macronutrient fuel choice is fundamental to understanding the mechanisms influencing food intake behavior, energy expenditure, and ultimately, weight gain and body composition. Suc | Health and Human Services, Department of / National Institutes of Health | 3/05/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $228,059 | Grant | Trans-NIH Recovery Act Research Support: This project titled 'GPU Computing Enabled Linux Computer Cluster ' is to set up a medium-sized specialized GPU computing enabled computer cluster equipment for fast processing of very large electron cryomicroscopy (cryoEM) datasets to facilitate routinel | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF WASHINGTON | $312,504 | Grant | Trans-NIH Recovery Act Research Support: Acquisition of a modern state-of-the art analytical ultracentrifuge (AUC) by the University of Washington School of Medicine is sought. Analytical ultracentrifugation is a powerful technique to characterize the size, shape, and oligomerization state of pr | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | $99,873 | Grant | Trans-NIH Recovery Act Research Support: Islet amyloid is a pathological feature of type 2 diabetes and contributes to +?-cell mass loss. It contains the unique peptide islet amyloid polypeptide (IAPP), also known as amylin, and when this peptide aggregates it is toxic to the +?-cell. The purpos | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $39,564 | Grant | Trans-NIH Recovery Act Research Support: XLocs and Gsa, the alpha subunit of the stimulatory G protein (Gsa), are two related proteins derived from the same gene locus, GNAS. XLas differs from the alpha subunit of the stimulatory G protein (Gsa) by a large N-terminal domain with unique sequence. | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| THE INSTITUTE FOR CANCER RESEARCH | $125,322 | Grant | Trans-NIH Recovery Act Research Support: Research into the mechanisms that specify chromosome segregation has revealed a plethora of new anti-cancer drug targets. In spite of these new discoveries, the mechanism by which inhibitors of mitosis kill tumor cells remains poorly understood. From a cl | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| UNIVERSITY OF TEXAS M D ANDERSON | $235,750 | Grant | Trans-NIH Recovery Act Research Support: Cell-based immunotherapies hold great promise for treatment of malignancies, yet they are among the greatest challenges to develop and implement in modern medicine. There are typically no or few markers such as distinct clinical features, specific morphol | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| THE MIRIAM HOSPITAL | $70,308 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is designed to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in a sample of over 5,000 overweight individuals with diabetes. Genetic markers are increasingly being identified that are associated with c | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $79,318 | Grant | Trans-NIH Recovery Act Research Support: The development of cell shape and three-dimensional organization (cellular morphogenesis) is a process of fundamental importance in cellular and developmental biology. Defects in cellular morphogenesis are also implicated in disease states such as birth | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $40,104 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement is to increase the researcher's effort to directly enhance and accelerate the aims of the parent grant in both cultured cell lines and in mouse model systems and to provide supplemental funds to purchase equipmen | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $205,759 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In this proposal, seven faculty of the Department of Biology and of the Koch Institute for Integrative Cancer Research at MIT request funding to upgrade the liquid-handling robot at MIT's BioMicro Center, a core facili | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| APPLIED BIOSYSTEMS, LLC | $30,124 | Contract | : Sale of equipment & supplies, Step One catalog number 437658 | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $499,785 | Grant | Trans-NIH Recovery Act Research Support: The ARRA award is an S10 grant to provide funding for a new LSRII flow cytometer. This will be a vital shared resource for the many investigators working on NIH-funded projects in our new Institute for Regenerative Cures. | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Polycystic Kidney Disease (PKD) causes renal failure due to progressive tubular cystic expansion. Mutations of PKD1 are responsible for 85% of ADPKD (autosomal dominant PKD), and the gene product (polycystin-1, PC1) is a large complex protein. Polycystin- | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $57,045 | Grant | Trans-NIH Recovery Act Research Support: The first aim of this renewal is to test a conceptual model linking pre-college students characteristics to students experience in the MSP and success in college, and in turn, the pathways from these college variables to PhD pursuit and receipt. This pro | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $72,303 | Grant | Trans-NIH Recovery Act Research Support: Fundamental information about how DMP1 and DSPP affect the formation of bone and dentin is essential to enhanced understanding concerning the pathogeneses of bony and dental defects associated with systemic diseases such as osteomalacia, osteoporosis and | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): High resolution morphological surface analysis is an integral part of biological investigations under both physiological and pathological conditions. The fine structure modifications induced during cell motility or cel | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $114,575 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): One route to regenerative medicine will involve introduction of stem or progenitor cells to repair damaged tissues. Maximizing the contribution of such cells will be important. Cell competition for growth and survival | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| WASHINGTON UNIVERSITY, THE | $118,849 | Grant | Trans-NIH Recovery Act Research Support: Although the regulation of gene expression has been intensively studied in the yeast S. cerevisiae, much about this process remains unknown. This is exemplified by our inability to predict, as opposed to explain, the expression pattern of any gene given i | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $77,687 | Grant | Trans-NIH Recovery Act Research Support: We are requesting an Administrative Supplement to our existing NEI-sponsored R01, Mechanisms of Learning a Visual Discrimination, which examines neural mechanisms of learning. The proposal meets the criteria of the ARRA, in that it will accelerate high-im | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $53,240 | Grant | Trans-NIH Recovery Act Research Support: DNA replication creates a pair of sister chromatids that are held together along their lengths by a ring-shaped protein complex known as cohesin. The phenomenon plays a central role in accurately segregating chromosomes between dividing cells, as well as | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF UTAH, THE | $127,925 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Recent advances in structural biology have enormously changed our understanding of how proteins are synthesized, how several antibiotics selectively mediate their effects and how to predict potential new antibiotic tar | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| UNIVERSITY OF UTAH, THE | $978,822 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application addresses broad Challenge Area (14) Stem Cells, and specific Challenge Topics 14-HL- 102: Bio-models and scaffolds for blood cell production and tissue regeneration and 14-DK-102: Discovery of methods | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| UNIVERSITY OF TEXAS M D ANDERSON | $149,562 | Grant | Trans-NIH Recovery Act Research Support: Sequencing of the human genome and those of other organisms has revealed that a large percentage of pre-mRNAs are spliced in multiple patterns to produce mRNAs encoding distinct proteins. Although alternate splicing is widespread and must regulate the exp | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $33,482 | Grant | Trans-NIH Recovery Act Research Support: Title: Living Donor Liver Transplant: Short & Long-Term Impact on Donors and Recipients - Funds provided to purchase an instrumentation and flow probes to perform the intra-operative measurements of blood flow to the liver vessels in the normal donors and | Health and Human Services, Department of / National Institutes of Health | 9/30/2010 |
| MCLEAN HOSPITAL CORPORATION, THE | $53,917 | Grant | Trans-NIH Recovery Act Research Support: This is a first resubmission of a K23-Mentored Patient-Oriented Research Career Development Award application entitled MRS Studies of Glutamate and GABA in Bipolar Disorder. The candidate's background is in postmortem studies of cellular abnormalities in | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $110,811 | Grant | Trans-NIH Recovery Act Research Support: The control of mRNA/protein complexes (mRNPs) is critical to animal development and cell function. Little is known about how specific mRNPs are regulated, and how this control is organized in the cytoplasm of living cells. This project plans to use C. ele | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $98,440 | Grant | Trans-NIH Recovery Act Research Support: The increasing incidence of obesity is a major health issue facing the USA. Moreover, the mechanisms underlying anorexia nervosa remain poorly understood. Fortunately, in the past decade several key hormones and CMS pathways controlling body weight and gl | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| BECTON, DICKINSON AND COMPANY | $35,000 | Contract | : Purchase of Flow Cytometer Option | Health and Human Services, Department of / National Institutes of Health | 2/03/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $251,444 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to elucidate mechanisms involved in the control of metabolism by insulin in skeletal muscle and fat cells. Both whole animal and cell culture models suggest that significant changes in phospholipid and TAG intermediates | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Determining the role of motor protein Myo1c in kidney biologySpecific Aims:This award was a supplement (as described below) to my previous K award that was aimed at investigating the hypothesis that Neph1 and the associated foot process junctional protein | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $435,500 | Grant | Trans-NIH Recovery Act Research Support: This application requests funds for the purchase of a BD FACSAria II flow cytometer / cell sorter. This application arises from the breakdown of the current flow cytometer, and from a growing demand for flow cytometric cell sorting services among a user g | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| ROBERTS OXYGEN COMPANY, INC. | $2,936 | Contract | : CRYOGENIC EQUIPMENT | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $148,500 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement Funds will allow continued funding of jobs created and work to be performed on core gastroparesis grants (Registry and NORIG studies). These funds will be utilized in the next 9 months to fund a post doctoral research position | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $262,416 | Grant | Trans-NIH Recovery Act Research Support: The so-called metabolic syndrome refers to a group of chronic diseases which appear to cluster in certain individuals. What appears to be central to these conditions is the existence of insulin resistance. Truncal adiposity, including fat stored in the in | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,815 | Grant | Trans-NIH Recovery Act Research Support: Glucose-stimulated insulin secretion (GSIS) from pancreatic islets is defective in Type 2 diabetes (T2DM). In healthy islets, GSIS is triggered by a complex network of intracellular signals (including [Ca2+]i) following glucose uptake and metabolism. Osci | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $496,331 | Grant | Trans-NIH Recovery Act Research Support: Research Computing Support (RCS), the high performance computing shared resource of the Fred Hutchinson Cancer Research Center, will be utilizing funds awarded to upgrade a 243-node high performance computing (HPC) cluster. The new system will offer a 15 | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $64,027 | Grant | Trans-NIH Recovery Act Research Support: Klf4 (Kruppel like factor 4, previously known as GKLF) is an epithelial zinc finger protein which controls cellular proliferation and differentiation in the skin and gastrointestinal tract. Klf4 mRNA is found at high evels in growth arrested cells and is | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| UNIVERSITY OF ALASKA FAIRBANKS | $7,425,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Center for Alaska Native Health Research (CANHR) conducts health disparities research in partnership with Yup'ik Eskimo communities in rural Southwest Alaska. The University of Alaska Fairbanks (UAF), on behalf of CANHR anand the Specialized Neuroscienc... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Specific Aim: To identify additional novel methylated genes involved in the initiation and progression of Barrett's esophagus and esophageal adenocarcinoma through the use of genome-wide methylation studies using Illulmina-?'s Infinium HumanMethylation27 | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $137,388 | Grant | Trans-NIH Recovery Act Research Support: The parent grant of this supplement application targets the development of computational tools for determining the structures of large protein complexes by combining atomic models of components with electron microscopy reconstructions in the resolution ra | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF ALASKA FAIRBANKS | $435,300 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Out-of-hospital cardiac arrest (CA) affects more than 300,000 people annually in the United States, with morbidity and mortality rates that have not improved in 50 years. Therapeutic hypothermia is currently the only t | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| KEYENCE CORP OF AMERICA | $48,670 | Contract | : Contract for Micro Analysis Division of Keyence. Maintaining personnel in that division. | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $82,786 | Grant | Trans-NIH Recovery Act Research Support: Natural products isolated from plants, bacteria, fungi, and many marine organisms have dramatically changed the course of human existence as is evidenced by the increased life expectancy since the 1940s. Many of these secondary metabolites function as ant | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $40,318 | Grant | Trans-NIH Recovery Act Research Support: The principle objective of this proposal is the development of general methods to produce robust synthetic nano-size polymers with the capacity to bind selectively to targeted peptides and proteins. In certain applications where cost, availability and/or | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Non-alcholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are important causes of chronic liver disease in the United States. The NASH Clinical Research Network (NASH CRN) was established in 2002 to conduct research related to its | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| TRUSTEES OF DARTMOUTH COLLEGE | $9,302,291 | Grant | National Center for Research Resources, Recovery Act Construction Support: The current fee-for-service health care system places extraordinary pressures on clinical translational research, especially activities which take place in high-cost, revenue generating facilities such as surgical operating rorooms and imaging suites. These... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $45,000 | Grant | Trans-NIH Recovery Act Research Support: The thyrotropin (TSH) receptor (TSHR) is the primary antigen of Graves' disease and the target for thyroid stimulating 'TSHR antibodies (TSHR-Ab)found in the serum of such patients. TSHR-Ab are characterized by their prolonged action and were originally c | Health and Human Services, Department of / National Institutes of Health | 1/30/2010 |
| UNIVERSITY OF WASHINGTON | $101,673 | Grant | Trans-NIH Recovery Act Research Support: Each year in the United States approximately 2.5 million individuals are hospitalized after sustaining traumatic physical injuries. Injured patients are at high risk for developing posttraumatic stress disorder (PTSD) and related comorbidities. High quali | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $97,941 | Grant | Trans-NIH Recovery Act Research Support: Principal Investigator/Program Director (Last, first, middle): Burgess, Shawn, C RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? m Yes l No 1.a. If YES to Human Subjects Is the IRB review Pending? m Yes m No IRB Approval Dat | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $81,126 | Grant | Trans-NIH Recovery Act Research Support: ATP-sensitive potassium (KATP) channels play a key role in coupling cell metabolism to cell excitability and govern diverse physiological processes including hormone secretions, control of vascular tone, and modulation of the activity of cardiac muscle an | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,932,637 | Contract | : After responding to a Request for Proposal issued by the National Institutes of Health entitled Recovery Act Contract Action: Providing Radiologic Outcomes for the Osteoarthritis Initiative, the Osteoarthritis Initiative (OAI) study received funding from | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| VEEX INC | $36,970 | Contract | : Telecommunications Test Equipment | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $825,073 | Grant | Trans-NIH Recovery Act Research Support: Our prior work has focused on the molecular mechanisms underlying Drosophila's circadian rhythms. Orthologs of genes initially characterized in Drosophila have now been linked to the control of rhythmic behavior and physiology in vertebrates, including fi | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| HAMPTON UNIVERSITY | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Hampton University (HU) Biomedical Research Center (BRC) will be a genuine national resource: a state-of-the-art, interdisciplinary, research facility situated on campus at an Historically Black University. The BRC will bebecome a flagship for integrate... Show more | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| THE VANDERBILT UNIVERSITY | $342,000 | Grant | Trans-NIH Recovery Act Research Support: We propose an upgrade to our existing Superconducting QUantum Interference Device (SQUID) biomagnetometer (Tristan Model 637i) that will allow us (1) to increase the spatial resolution by installing additional channels; and (2) to add additional magnetic | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $110,263 | Grant | Trans-NIH Recovery Act Research Support: University of North Carolina AIDS Clinical Trials Unit (ACTU)-ARRA. Since 2003, UNC-CH has collaborated with the North Carolina Department of Public Health in a statewide HIV testing initiative to detect AHI and has enrolled consenting patients in AHI pr | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $7,400 | Grant | Trans-NIH Recovery Act Research Support: Adult to Adult Living Donor Liver Transplantation in Adults (A2ALL) Cohort Study We are re-cutting, and staining 600 subjects liver biopsy slides for review by a single pathologist for standardized reading. We are interested in eliminating inter-observer | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| SOUTH DAKOTA STATE UNIVERSITY | $430,296 | Grant | Trans-NIH Recovery Act Research Support: Oxidative stress has been associated with various health issues. Amethod which can detect the status of oxidative stress in intact cells will help understand the role of ocidative stress in various diseses and dacilitate development of treatments to oxid | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $98,751 | Grant | Trans-NIH Recovery Act Research Support: Prolactin is essential for a number of bodily processes including reproduction and immune function. Despite the importance of this hormone, little information is available on the manner in which it is expressed in individual secreting cells. Recent eviden | Health and Human Services, Department of / National Institutes of Health | 3/12/2010 |
| UNIVERSITY OF UTAH, THE | $206,825 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The homeodomain-containing transcription factor Chx10 is a central regulator of retinal development. Much of what we know about Chx10 function comes from studies using ocular retardation J (orJ) mice, which have a null | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $181,066 | Grant | Trans-NIH Recovery Act Research Support: Not Started | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $1,557,486 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Forsyth Institute, the world's leader in oral and craniofacial disease research, requests $3.79 million to renovate 8,935 ft2 of space for laboratory, core facility, office and clinical research use to create a new interdidisciplinary research center of... Show more | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $67,074 | Grant | Trans-NIH Recovery Act Research Support: Project description: The overall hypothesis for the parent grant is that pain associated with painful bladder syndrome (PBS)/interstitial cystitis (IC) involves an alteration of visceral sensation/bladder sensory physiology. -?The working hypothesis for t | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $402,285 | Grant | Trans-NIH Recovery Act Research Support: High-throughput screening (HTS) of small molecule libraries is a widely recognized and increasingly important method for identifying compounds that modulate biological processes. Small molecule compounds thus identified can be powerful molecular probes fo | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $1,472,252 | Grant | Trans-NIH Recovery Act Research Support: Xenotransplantation could provide a solution to the critical shortage of donor organs that limits the field of transplantation today. The parent grant for which this Supplement is requested is a Program Project Grant (P01AI45897) entitled ?A Tolerance App | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $21,818 | Grant | Trans-NIH Recovery Act Research Support: Diabetes is a major public health problem in the United States and the world, with a huge societal cost in both human and financial terms. Phosphoinositide 3-kinases (PI 3-kinases) are lipid kinases that play an essential role in insulin action. While the | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF CONNECTICUT | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Acetaminophen (APAP), a commonly used over the counter analgesic and antipyretic drug, is responsible for 50% of all cases of drug-induced liver injury in the United States. An aspect of APAP hepatotoxicity that is less known is the development tolerance | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $56,266 | Grant | Trans-NIH Recovery Act Research Support: Aminoacyl-tRNA synthetases (ARSs) play a key role in one of the most important cellular processes, namely protein biosynthesis. They catalyze the covalent attachment of amino acids to their cognate transfer RNAs(tRNAs), an essential step in translation o | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| BAYLOR COLLEGE OF MEDICINE | $14,895,273 | Grant | National Center for Research Resources, Recovery Act Construction Support: DESCRIPTION (provided by applicant): The objective of this proposal is to build out 3 floors (total) in the Jan and Dan Duncan Neurological Research Institute (NRI) to accelerate research in understanding and treating disorderers of the brain and mind. Bayl... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $25,956 | Grant | Trans-NIH Recovery Act Research Support: We believe that this direct experience with health services research, combined with the didactic and mentoring aspects built into the SUMR program, will encourage interested students to pursue health related research careers. It may also feed the pipeline | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| HARTFORD HOSPITAL | $3,271,583 | Grant | National Center for Research Resources, Recovery Act Construction Support: To construct and renovate a total of 8700 square feet, which includes the expansion of an MRI Suite and associtate equipment and control rooms and a Research Staff Office Building in support of the Olin Research Center. | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The intestine is a complex and dynamic organ that, under normal physiologic conditions, performs a number of functions in the organism, some of which, including nutrient absorption, are essential for survival. The intestine is subject to pathologic distur | Health and Human Services, Department of / National Institutes of Health | 1/19/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $14,824,023 | Grant | National Center for Research Resources, Recovery Act Construction Support: In recognition of the critical role that social, psychological, and lifestyle factors (social determinants of health) play in disease onset, progression, and amelioration, the NIH over the last two decades has supported an incncreasing portfolio of extramur... Show more | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| DUKE UNIVERSITY | $97,305 | Grant | Trans-NIH Recovery Act Research Support: Decision-Making For Infants with Complex Life-Threatening Conditions Abstract Infants with life-threatening conditions who earlier would have died in the first months of life are now receiving highly complex and sometimes experimental treatments designed | Health and Human Services, Department of / National Institutes of Health | 2/23/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $51,709 | Grant | Trans-NIH Recovery Act Research Support: Gastrointestinal Peptide Signaling Through PKC/PKD Many gastrointestinal (GI) peptides, neurotransmiters and bioactive lipids bind to G protein-coupled receptors (GPCRs) and stimulate long-term biological responses, including cell migration and prolifera | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $162,418 | Grant | Trans-NIH Recovery Act Research Support: This project was a supplement that evaluated the role of microbial translocation and potential co pathogens in early immune recovery and clinical outcomes after HAART initiation in adults with HIV and active tuberculosis in Botswana. | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| CLAREMONT GRADUATE UNIVERSITY | $406,758 | Grant | Trans-NIH Recovery Act Research Support: associative effects have been shown to consistently predict level of use but have not yet been empirically linked to likely neural substrates. The application of associative memory concepts from basic science research suggests that one?s behavior at any m | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF CINCINNATI | $47,000 | Grant | Trans-NIH Recovery Act Research Support: Liver disease has emerged as a major source of morbidity and mortality in the United States with a disproportionate representation in some identifiable groups. Furthermore, unique management and treatment issues are associated with identifiable groups whi | Health and Human Services, Department of / National Institutes of Health | 1/20/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $14,954,444 | Grant | National Center for Research Resources, Recovery Act Construction Support: This is a request for $14,954,444 million dollars in renovation funds to complete 63,397 square feet of shell space in a newly constructed biomedical research building. The project will complete three floors of what is currentntly termed the Phase V researc... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $254,216 | Grant | Trans-NIH Recovery Act Research Support: Award description: Studies suggest that a large proportion of travelers engage in behaviors that place them at risk for HIV, hepatitis B (HBV) and hepatitis C (HCV) infection. As a supplement to the grant entitled 'International Mobility of HIV', we will | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| MICHIGAN STATE UNIVERSITY | $91,093 | Grant | Trans-NIH Recovery Act Research Support: To advance progress in Specific Aim 3 of the parent grant: Identify lipid binding motifs within lipid droplet associated proteins, we request funds to: (1) Hire an additional member to the research team; (2) Replac | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $54,881 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to investigate the morphogenesis of the coronal suture and mechanisms of coronal synostosis. The long-term aim is to understand how boundaries between cellular compartments form, and how such boundaries function in growth control and pa | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| THE JACKSON LABORATORY | $543,171 | Grant | Trans-NIH Recovery Act Research Support: The Jackson Laboratory (Jackson) is a world-class research center focusing on the use of mammalian genetics to interrogate human disease. It is increasingly clear that most, if not all, diseases are ultimately influenced by a complex mix of genetic factor | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| MAYO CLINIC | $1,911,769 | Grant | Trans-NIH Recovery Act Research Support: The U.S. Department of Health and Human Services report '2020:A New Vision' highlights that regenerative medicine is the vanguard of the 21st century healthcare. From bone marrow transplants five decades ago to the most recent stem cell-derived organ tran | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF ROCHESTER | $921,000 | Grant | Trans-NIH Recovery Act Research Support: The central hypothesis of this application is that impairment of myelination, irrespective of the mechanisms, can be diagnosed and characterized by utilizing auditory brain stem recordings and analysis as a sensitive and non-invasive diagnostic tool. We | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $71,558 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this application is to request salary support for retaining an experienced postdoctoral fellow, Dr. Nianlan Yang. Dr. Yang is intelligent, had very good training in molecular biology and excellent track record. With this support, Dr. Yang | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| MICHIGAN STATE UNIVERSITY | $200,481 | Grant | Trans-NIH Recovery Act Research Support: Using tomato (Solanum lycopersicum) and Arabidopsis thaliana (a small flowering plant native to Europe, Asia and northwestern Africa) as experimental model systems, the researcher will study the mechanism by which plants defend themselves against attack b | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Within the human adrenal, the zona glomerulosa produces aldosterone, the fasciculata produces cortisol and the reticularis produces the adrenal androgens, mainly DHEA and DHEA-sulfate. Adrenarche refers to the onset of adrenal reticularis production of a | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $53,796 | Grant | Trans-NIH Recovery Act Research Support: The goals of this supplement was to increase the tempo of my research by providing additional funding to make a half-time research coordinator full-time and therefore allow the coordinator to dedicate more time to patient recruitment in the fracture group | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $150,410 | Grant | Trans-NIH Recovery Act Research Support: Visual perception is mediated by complex interactions amongst neurons in the retina, visual cortex, and subcortical brain structures. The importance of vision to humans and other primates is reflected in the enormous percentage of cerebral cortex devoted | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF ROCHESTER | $187,480 | Grant | Trans-NIH Recovery Act Research Support: The two major goals in the parent grant for which this application requests an administrative supplement were: (1) test the hypothesis that myofibroblasts, through localized contraction of the corneal stroma, are responsible for the significant increase i | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF PITTSBURGH THE | $50,798 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this project is to accelerate the dissemination of findings from the SMART Trial. Funding was requested to hire a statistician to contribute a significant level of effort to this project. At this time data are available for the 6 m | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| AGILENT TECHNOLOGIES, INC | $31,559 | Contract | : G2943CA-2100 Bioanalyzer laptop system Includes 2100 Bioanalyzer with HP/Compaq laptop PC, printer, 2100 expert software vortex mixer, accessories. Does not include cartridge nor license. G2947CA-2100 Bioanalyzer electrophoresis set. Includes electrode ca | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| OREGON SOCIAL LEARNING CENTER | $76,475 | Grant | Trans-NIH Recovery Act Research Support: A Culturally Specific Intervention for Latino Families. The purpose of the project supported through the Summer Research with NIDA program is threefold: (1) to provide students from diverse backgrounds with fundamental knowledge and a skill set that will | Health and Human Services, Department of / National Institutes of Health | 6/20/2009 |
| UNIVERSITY OF WASHINGTON | $91,639 | Grant | Trans-NIH Recovery Act Research Support: The requested $90,333 will be used for the purchase of a new MicroBeta scintillation counter as a replacement of the current aging machine located at South Lake Union, Hampe Lab.($91,751 with indirect costs) | Health and Human Services, Department of / National Institutes of Health | 3/30/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Central goal is to elucidate the role of a MAP3K known as MLK3 (mixed lineage kinase-3) in inducing beta cell death. The rationale behind our studies is the demonstration that both cytokines and lipids, like ceramide, act as specific agonists of MLK3, su | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY | $348,275 | Contract | : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| CEDARS-SINAI MEDICAL CENTER | $73,209 | Grant | Trans-NIH Recovery Act Research Support: This application proposes a 5 year translational research training program for the development of an academic career in urologic oncology. The applicant completed urology residency at the University of Chicago and fellowships in urologic oncology and mini | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| UNIVERSITY OF WASHINGTON | $53,440 | Grant | Trans-NIH Recovery Act Research Support: This application describes a two-year Administrative Supplement to the remaining years of my five-year mentored training program to develop an independent clinician-scientist whose career in academic medicine will further our understanding of human red bl | Health and Human Services, Department of / National Institutes of Health | 2/15/2010 |
| UNIVERSITY OF WASHINGTON | $85,000 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an Administrative Supplement on NIDDK grant 5RO1DK074758 entitled Peripheral and Central Inflammatory Signals in the Sickness Response (PI: Brent E. Wisse, MD). The rationale for this request is based on exciting new data justifying | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| MIAMI UNIVERSITY | $58,092 | Grant | Trans-NIH Recovery Act Research Support: The 3' untranslated region (UTR) and the poly(A) tail of an mRNA can exert regulatory influences that affect message stability, rate of translation, and/or subcellular localization. Thus, the choice of where the cleavage reaction takes place in a pre-mRNA | Health and Human Services, Department of / National Institutes of Health | 1/22/2010 |
| LINCOLN UNIVERSITY | $343,215 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of GMaP is to create state-of-the-art regional networks or centers dedicated to cancer health disparities research and care. This award covers Area 5, which includes Massachusetts, Michigan, Minnesota, New York, Ohio, and Pennsylvania | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| NEUROSCIENCE RESEARCH INSTITUTE OF NORTH CAROLINA | $412,500 | Grant | Trans-NIH Recovery Act Research Support: The project aims to determine neuronal activity that is predictive of seizures in rat models of spontaneous seizures induced in the amygdala of the brain. Neuron ensembles will be recorded in amygdala and hippocampus. Pattern recognition techniques will | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this proposal is to refine magnetic resonance (MR) imaging and spectroscopy to provide a comprehensive non-invasive assessment of patients with non-alcoholic fatty liver disease (NAFLD). The specific aims are to implement and develop MR met | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| UNIVERSITY OF OREGON | $209,413 | Grant | Trans-NIH Recovery Act Research Support: Steroid hormone receptors play key roles in cancer as well as numerous other diseases and conditions affecting metabolism, immunity, and reproduction. Evolutionary studies are a powerful means to characterize protein structure-function relations, the fund | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| UNIVERSITY OF CHICAGO, THE | $55,207 | Grant | Trans-NIH Recovery Act Research Support: The asymmetric self-renewal divisions of adult stem cells underlie the continued homeostasis of many tissues of the body. Most, if not all, stem cells are present in a microenvironment, called a niche that provides three conditions necessary for long-term | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF FLORIDA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent grantis to determine the host specific factors that confer susceptibility to urinary tract infection (UTI) complicated by struvite baldder stone foramtion. The parent grant uses a rodent model of UTI caused by the human pa | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $237,082 | Grant | Trans-NIH Recovery Act Research Support: During this AI52218 funding period, we have developed novel high throughput screens for both nucleotidylyltransferases and glycosyltransferases which, in conjunction with directed evolution, has greatly advanced the discovery of unique catalysts specifica | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| UNIVERSITY OF ILLINOIS | $104,418 | Grant | Trans-NIH Recovery Act Research Support: The aminoacyl-tRNA synthetases (aaRSs) comprise a family of twenty enzymes that are essential to every living organism. Each enzyme recognizes a single cognate amino acid and covalently attaches it to the correct tRNA. The charged tRNA then transfers the | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF NEBRASKA | $101,371 | Grant | Trans-NIH Recovery Act Research Support: Apoptosis, or programmed cell death, is a biochemical pathway critical to normal development and tissue homeostasis in multi-cellular organisms. Aberrant suppression of apoptosis is a requisite contributor to human cancer. The long-term objective of this | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| THE VANDERBILT UNIVERSITY | $459,995 | Grant | Trans-NIH Recovery Act Research Support: This application requests funds to purchase a dedicated ClonePix FL system (Genetix Ltd.) to automate the screening and selection of monoclonal antibody-secreting hybridoma cell lines. The instrument will be housed and operated by the Vanderbilt Monoclona | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| EAST CAROLINA UNIVERSITY | $358,750 | Grant | Trans-NIH Recovery Act Research Support: Our hypothesis is that expression of Zfp206 is essential for maintenance of the differentiation potential and as terminal differentiation is established with the expression of PPARy, Zfp206 expression is diminished. The transient expression of the splice | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| BECTON, DICKINSON AND COMPANY | $297,000 | Contract | : Purchase of Flow Cytometer Laser Option | Health and Human Services, Department of / National Institutes of Health | 12/01/2009 |
| BENEDICT COLLEGE, THE | $78,904 | Contract | : Biomedical Research, Student Research and to purchase DNA Analyzer System | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $414,375 | Grant | Trans-NIH Recovery Act Research Support: PROJECT 1 DESCRIPTION (Understanding host-viral interaction is an essential step in developing safe and effective antimicrobials against biodefense agents and emerging pathogens. Early detection of invading viruses by the host depends on a limited number | Health and Human Services, Department of / National Institutes of Health | 6/01/2010 |
| UNIVERSITY OF KENTUCKY | $3,095,885 | Grant | Trans-NIH Recovery Act Research Support: This grant is to support the acquisition of a high-field small animal imager to support multiple NIH- funded investigators using small animals for biomedical research. The imager selected is a 7T Bruker ClinScan system which incorporates the advantages of | Health and Human Services, Department of / National Institutes of Health | 5/27/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $410,602 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The UT Southwestern high-throughput screening (HTS) laboratory creates and conducts screens of small molecules to identify those that can become leads for developing therapeutics or used as tools in research. In additi | Health and Human Services, Department of / National Institutes of Health | 4/29/2010 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $6,648,467 | Grant | Trans-NIH Recovery Act Research Support: Complex human diseases, such as hypertension and renal disease, are major health problems in the United States. The National Heart, Lung, and Blood Institute (NHLBI) has invested in many genome-wide association studies (GWAS) and other types of genetic an | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $441,632 | Grant | Trans-NIH Recovery Act Research Support: Advances in mass spectrometry instrumentation and methods have pushed mass spectrometry to the forefront in modern biomedical research. Electrospray and matrix-assisted laser desorption have dramatically extended the range of molecular weights that can b | Health and Human Services, Department of / National Institutes of Health | 4/22/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $42,634 | Grant | Trans-NIH Recovery Act Research Support: Skin color plays a distinct role in the detection of and perhaps the protection from skin injury in sexual assault. We have found significant differences in ano-genital injury prevalence in Black and White females after consensual sexual intercourse and s | Health and Human Services, Department of / National Institutes of Health | 5/13/2010 |
| UNIVERSITY OF CHICAGO, THE | $156,000 | Grant | Trans-NIH Recovery Act Research Support: The broad objective of this research proposal is to advance understanding of thyroid physiology through study of genetic defects at key regulatory processes. More specifically, research is centered on the mediation of thyroid hormone (TH) effects by study | Health and Human Services, Department of / National Institutes of Health | 4/15/2010 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $91,871 | Contract | : MSKCC has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas project. Specifically this award is to fund the provision of breast cancer specimens (N=55). These are predominantly retrospective specimens. These cases are | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $999,659 | Grant | Trans-NIH Recovery Act Research Support: The recent breakthrough of direct reprogramming adult mouse and human fibroblasts toward a pluripotent state by introducing Oct3/4, Sox2, Klf4, and c-Myc, has brought new hope for the generation of patient- and disease- specific stem cells without the eth | Health and Human Services, Department of / National Institutes of Health | 1/13/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $93,491 | Grant | Trans-NIH Recovery Act Research Support: We have recently described a network of protein-protein interactions that tethers the highly repetitive yeast ribosomal DNA (rDNA) repeats to the inner nuclear membrane. Two inner nuclear membrane proteins, Heh1 and Nur1, mediate this tethering, which is | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| LEICA MICROSYSTEMS INC | $28,672 | Contract | : PURCHASE OF CM1950 CRYOSTAT | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $49,900 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to understand the mechanisms by which extracellular stimuli can regulate protein expression in a cell through the process of signal induced alternative splicing. This supplement will accelerate progress toward increasing our u | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $342,226 | Grant | Trans-NIH Recovery Act Research Support: A major goal in neurobiology is the identification of functional neuronal pathways. Classical anatomical tracing techniques allow connectivity between brain regions to be determined. Lesion studies and anatomically restricted infusioon of pharmacologica | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $363,171 | Grant | Trans-NIH Recovery Act Research Support: The purchase of a bioluminescent imaging (BLI) system is requested for the core imaging facility at the University of California San Diego Medical Center (UCSDMC), Hillcrest. While various microscopes, and non-invasive imagers (i.e. magnetic resonance ima | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| YALE UNIVERSITY | $455,000 | Grant | Trans-NIH Recovery Act Research Support: We are requesting fund to purchase an Amis Image Stream, a unique instrument that combines flow cytometry with optical imaging to create a rea- sonbly detailed representation of each cell that passes through the chamber. This image is assembled from multi | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF IOWA, THE | $84,375 | Grant | Trans-NIH Recovery Act Research Support: Multidrug resistance often arises in human tumors due to overexpression of plasma membrane ATP-binding cassette (ABC) transporter proteins. Recent experiments have indicated that multidrug resistant cells frequently exhibit changes in the profile of lipid | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| YALE UNIVERSITY | $111,502 | Grant | Trans-NIH Recovery Act Research Support: Regulated proteolysis is used to drive many biological processes, including the cell cycle, cell death, and embryonic patterning. It is also thought to mediate complex brain functions such as learning and memory. Not surprisingly, then, defects in regulat | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| ALBANY MEDICAL COLLEGE | $9,173,559 | Grant | National Center for Research Resources, Recovery Act Construction Support: Albany Medical College (AMC) is a private medical and graduate education institution unaffiliated with the State University of New York (SUNY) or any other university system. Basic and translational biomedical research is cururrently confined to two adjoin... Show more | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| YALE UNIVERSITY | $105,620 | Grant | Trans-NIH Recovery Act Research Support: MicroRNAs (miRNAs) are an abundant family of endogenous approx 21nt small RNAs that repress gene expression post-transcriptionally. More than 4percent of the human genes encode for miRNAs and current estimates suggest that miRNAs could target more than 30 | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $312,755 | Grant | Trans-NIH Recovery Act Research Support: Cardiac ultrasonography continues to be used frequently in experimental medicine for certifying in vivo the physiologic and anatomic characteristics of the cardiovascular system. Advances in ultrasound technologies now provide, both for embryos and small | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $9,609,225 | Grant | Trans-NIH Recovery Act Research Support: This application proposes to create a new energy-efficient Data Center that will house, power, cool, network, and safeguard the rapidly expanding high-performance computing and data storage systems that are essential to the research of Fred Hutchinson Can | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $91,570 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent proposal is to reveal molecular mechanisms by which stearoyl-CoA desaturase (SCD) expression partitions lipids between storage and oxidation. SCD is the central lipogenic enzyme catalyzing all in vivo reactions in the synt | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| BECKMAN COULTER, INC. | $51,912 | Contract | : Optima Max-XP Tabletop Ultracentrifugation and related hardware components | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $158,081 | Grant | Trans-NIH Recovery Act Research Support: Pseudohyphal and invasive growth in the yeast Saccharomyces cerevisiae require a signaling pathway that is mediated by the G protein beta-subunit Gpa2p and its coupled receptor Gpr1. Gpr1p is a low affinity glucose receptor that responds to high concentra | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| TRUSTEES OF BOSTON UNIVERSITY | $104,861 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to provide additional funds to assess by multiplex technology sera obtained from patients enrolled in the parent clinical trial. The results will provide a deeper understanding of the serum status of the enrolled patients | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $101,364 | Grant | Trans-NIH Recovery Act Research Support: Genetic Architecture of Voluntary Exercise in Mice - ARRA Exercise induces metabolic changes including loss of weight, reduction in triglyceride and LDL levels, increased HDL, and enhanced insulin sensitivity. Moderate physical activity has been shown to | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| CITY & COUNTY OF SAN FRANCISCO | $9,508,907 | Grant | National Center for Research Resources, Recovery Act Construction Support: The award provides funding for the expansion & renovation of 17,417 sq ft of space at 25 Van Ness Avenue. The project will expand, renovate, & reorganize the three (3) Research units of the San Francisco Department of Public c Health to maximize efficiency... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| CRESS LLC | $93,640 | Grant | Trans-NIH Recovery Act Research Support: Ananlysis of children's speech | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CAL POLY POMONA FOUNDATION INC | $130,602 | Grant | Trans-NIH Recovery Act Research Support: Cellular events typically require precise regulatory control. Regulation failures may lead to problems like uncontrolled cellular proliferation and cancer. The regulation of spermiogenesis in the model nematode Caenorhabditis elegans is the focus of the p | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| HEALTH RESEARCH, INC. | $59,664 | Grant | Trans-NIH Recovery Act Research Support: Ribosomes are large ribonucleoprotien complexes, which interact with protien factors and small RNA molecules to carry out life-sustaining process of protein biosynthesis, or translation, in all cellsm and in cellular organelles such as mitochondria. An u | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| EAST TENNESSEE STATE UNIVERSITY | $74,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to elucidate the biochemical basis of the functions of human replication protein A (RPA) in DNA damage responses, and to better understand the damage-induced mutagenesis and carcinogenesis. DNA damage has been widely implicated | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $33,924 | Grant | Trans-NIH Recovery Act Research Support: Inflammatory bowel diseases are devastating illnesses that cause significant morbidity and mortality. We have developed a mouse model of ulcerative colitis (UC) that resembles the human disease. Studies of this model will hopefully lead to the identific | Health and Human Services, Department of / National Institutes of Health | 2/23/2010 |
| YALE UNIVERSITY | $84,105 | Grant | Trans-NIH Recovery Act Research Support: The long term goals of this proposal are to elucidate the molecular mechanisms involved in normal and abnormal expression of the human erythrocyte membrane protein ankyrin. Ankyrin-1, an important component of the red cell membrane skeleton, is expressed | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The hepatitis C virus (HCV) poses a public health threat. It is important to identify viral factors that thwart natural defenses and contribute to treatment failure. In a cross sectional study, we recently found an inverse relationship between viral repli | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| PACIFIC NORTHWEST RESEARCH INSTITUTE | $82,075 | Grant | Trans-NIH Recovery Act Research Support: C57BLKS/J mice overexpressing the antioxidant enzyme glutathione peroxidase-1 (GPx-1) specifically in pancreatic beta-cells were generated. The GPx-1 transgene was introgressed into the beta-cells of db/db mice. The onset of hyperglycemia in db/db-GPx(+ | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $5,882,526 | Grant | National Center for Research Resources, Recovery Act Construction Support: Boston University proposes to implement plans for the renovation of four laboratory modules consisting of 6,700 square feet of research and support space in the Metcalf Center for Science and Engineering on the University's ChCharles River Campus (CRC). Thi... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| WASHINGTON UNIVERSITY, THE | $14,273,023 | Grant | National Center for Research Resources, Recovery Act Construction Support: Washington University School of Medicine has been at the forefront of genome science since the inception of the field. There is currently over $81 million in annual grant funding to support major sequencing and genome analysisis projects at The Genome Cente... Show more | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $6,616,774 | Grant | National Center for Research Resources, Recovery Act Construction Support: Funds are to support the renovation of the 2nd floor of the Basic Sciences Building (BSB) at the Medical University of South Carolina. The primary users are research faculty and trainees in the Microbiology & Immunology and P Pharmacology Departments. The... Show more | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $45,600 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests an Administrative Supplement for parent grant Growth Hormone signaling to the nucleus. The overall aim of the parent grant is to gain fundamental understanding of growth hormone (GH) action in normal and pathological conditions by u | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF CINCINNATI | $8,439,998 | Grant | Trans-NIH Recovery Act Research Support: The Medical Sciences Building (MSB) animal facility at the University of Cincinnati was constructed 35 years ago to house primarily large-animal species. MSB is currently unable to meet the present and future needs for bench and translational research uti | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| SAIC FREDERICK, INC | $450,000 | Contract | : Re-engineering Protocol Implementation & Development (RaPID) Recent independent analyses of the National Cancer InstituteG??s (NCI) clinical trials systems have indicated an urgent need to re-evaluate engrained processes for developing and implementing ph | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| UNIVERSITY OF PITTSBURGH THE | $144,189 | Contract | : The University of Pittsburgh has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of Breast ductal carcinoma (110 cases), Breast lobular carcinoma (15 c | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $92,377 | Grant | Trans-NIH Recovery Act Research Support: In the past funding period, we have performed novel studies demonstrating an important role for Wnt signaling as an inhibitor of adipogenesis in cultured preadipocytes and in transgenic mice. Our studies have demonstrated that Wnt10b is expressed in pread | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,460 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The ability of chromosomes to move towards opposite poles of the mitotic spindle is fundamental for proper cell division and defects in this process are believed to be an initial step in tumorigenesis. Poleward chromos | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $99,210 | Grant | Trans-NIH Recovery Act Research Support: The first specific aim of this supplement is to purchase a computer cluster and software that coordinates utilization of the computing cluster to rapidly process and quantify The first specifc aim of this supplement is to purchase a computer cluster and s | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $14,920,230 | Grant | National Center for Research Resources, Recovery Act Construction Support: This ARRA C06 project will renovate more than 40,000 gross square feet of existing space in the heart of the UCLA biomedical campus to create the Integrative Phenotyping Center for Neuropsychiatry (IPCN). High-throughput stratategies for deep and technicall... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF TEXAS AT AUSTIN | $25,361 | Grant | Trans-NIH Recovery Act Research Support: The goal of the current application is to provide Dr. Igor Ponomarev with career development opportunities under the mentorship of Dr. R. Adron Harris. The excellent research environment, faculty and facilities at the University of Texas at Austin will al | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $417,792 | Grant | Trans-NIH Recovery Act Research Support: The broad, long term objective of this application is to obtain funds to purchase a new JEOL JEM-1400 transmission electron microscope (TEM) for the Electron Microscopy Research Laboratory (EMRL) at the University of Kansas Medical Center (KUMC). This cor | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $89,878 | Grant | Trans-NIH Recovery Act Research Support: Oxidative phosphorylation (OXPHOS) refers to the cell's core biochemical pathway for generating ATP. During the past 20 years, it's become abundantly evident that both inborn errors of metabolism as well as common, degenerative diseases stem from OXPHOS d | Health and Human Services, Department of / National Institutes of Health | 2/15/2010 |
| UNIVERSITY OF UTAH, THE | $499,950 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We propose replacing an existing FACSVantage SE cell sorter at the University of Utah's Health Sciences Center with a four laser (405, 488, 561 and 640 nm) FACSAria-II SORP cell sorter. The existing instrument was purc | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $88,107 | Grant | Trans-NIH Recovery Act Research Support: The primary goals of this proposal are to develop improved methods for probing the structure and dynamics of RNAs by nuclear magnetic resonance (NMR) spectroscopy and the application of NMR and biochemical methods to understand the molecular determinants | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to K08 DK078014 provides salary support for a research assistant. The responsibilities outlined in the supplemental application indicate that research assistant support will enhance our ability to process and analyze data th | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| BAYLOR COLLEGE OF MEDICINE | $220,057 | Grant | Trans-NIH Recovery Act Research Support: The initial and current funding periods of the Nuclear Receptor Signaling Atlas has demonstrated the ability of the Consortium members to pursue the collective goal of generation and validation of high-content datasets and the distribution of these data t | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $102,334 | Grant | Trans-NIH Recovery Act Research Support: The RPS2 signal transduction pathway in Arabidopsis thaliana is currently one of the most advanced systems that have been studied in plants to elucidate the molecular basis of plant innate immunity. During this funding period we have continued to make exc | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| UNIVERSITY OF ILLINOIS | $80,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the requested supplement is to purchase a second pulsed, tunable laser source for our multi-photon microscope. The additional laser source will allow uncompromised multi-color fluorescence imaging and thereby accelerate all three Specific A | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| FLORIDA STATE UNIVERSITY, THE | $95,738 | Grant | Trans-NIH Recovery Act Research Support: The goal of this award is to advance and augment the aim of our project to define the functions of Centrosomin protein in the regulation of centrosome replication. To achieve this goal, we will hire one postdoctoral fellow to work on this project and also | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $137,515 | Grant | Trans-NIH Recovery Act Research Support: The function of the visual system is to form images in the brain. Correct specification and patterning of the photoreceptor neurons within the retina are a prerequisite for precise retinotopic axonal projections and image formation. The Drosophila eye ser | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| DUKE UNIVERSITY | $149,904 | Grant | Trans-NIH Recovery Act Research Support: Encouraged by its success, the NIDDK has issued RFA-DK-08-505 whose objective is to continue the NASH CRN for additional five years. The objectives of the NASH CRN during the next funding period are (a) to successfully complete three network-v'de studies | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $79,350 | Grant | Trans-NIH Recovery Act Research Support: An emerging theme in experimental therapeutics concerns the use of glucagon-like peptide-1-(7-36)- amide (GLP-1) and its synthetic peptide analogs (the incretin mimetics) to lower levels of blood glucose in Type 2 diabetic subjects. This action of GLP-1 r | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $100,000 | Grant | Trans-NIH Recovery Act Research Support: MU Opioid Receptor Function in the Enteric Nevous System Administrative supplement to parent grant titled -? opioid receptor function in the enteric nervous system This is an administrative supplement request to purchase equipment and to support an under | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $107,615 | Grant | Trans-NIH Recovery Act Research Support: The cone photoreceptors in the retina are responsible for day- and color vision. These cones are lost in many diseases of the retina which lead to severe vision deficit and even blindness. This research proposal supplement evaluates the recovery of functi | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $14,873,525 | Grant | National Center for Research Resources, Recovery Act Construction Support: This project, Cardiovascular and Regenerative Sciences in WIMR Phase II, is an integral component of the Wisconsin Institutes for Medical Research (WIMR) strategic initiative. WIMR embodies a three phase effort to broadly incocorporate the research enterpri... Show more | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $93,857 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the parent grant ?The Central Melanocortin System and the Regulation of Energy Balance? is to understand how the brain senses levels of peripheral energy stores and integrates these signals to maintain energy balance. The propo | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF TEXAS AT AUSTIN | $3,841,038 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests funds to complete construction of a new home for the Imaging Research Center at the University of Texas at Austin. This center is currently located several miles from the main campus, which limits its effectiveness and availability. | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $54,161 | Grant | Trans-NIH Recovery Act Research Support: Obesity has become a widespread health problem reaching an epidemic level in our society, with the affected individuals having a high risk for diabetes, heart disease, hypertension and cancer. The adipocyte- derived hormone leptin regulates energy balance | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $230,187 | Grant | Trans-NIH Recovery Act Research Support: Award Title: BIOCHEMICAL PREDICTORS OF TYPE 2 DM IN WOMEN Despite much progress in biomedical science, type 2 diabetes (T2D) continues to be a leading cause of death and disability for millions of Americans. The fundamental basis of T2D pathogenesis invo | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| SAINT LUKE'S HOSPITAL OF KANSAS CITY | $4,173,058 | Grant | Trans-NIH Recovery Act Research Support: Identify the barriers in implementing individualized informed consents in routine clinical care. Test the impact of Personalized Risk Information Services Manager (PRISM) on the quality of informed consent, on the use of Bleeding Avoidance Therapies (BAT | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE VANDERBILT UNIVERSITY | $100,011 | Grant | Trans-NIH Recovery Act Research Support: Transforming Growth Factor -B1 (TGF-B) key mediator in tissue fibrosis. TGF-B involved in: 1) Differentiation of myofibroblasts, primary source of ECM production; 2) Stimulate synthesis of many other matrix components, such as collagens, fibronectins, and | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| OHIO STATE UNIVERSITY, THE | $111,200 | Grant | Trans-NIH Recovery Act Research Support: In the past ten years investigators at Ohio State University have used the powerful technique of X-ray crystallography for a wide variety of high-impact NIH-funded research, including the discovery of the 22nd genetically encoded amino acid in nature, st | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| NEW YORK UNIVERSITY (INC) | $99,705 | Grant | Trans-NIH Recovery Act Research Support: Membrane transport, for example glucose uptake, Is essential to the cell. Such processes are often mediated by secondary membrane transporters. The largest secondary transporter family is the major facilitator superfamily (MFS), with more than 5,000 membe | Health and Human Services, Department of / National Institutes of Health | 3/22/2010 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $996,415 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic 08-CA-104: Regulatory functions of small RNAs. Our goal is to identify small RNAs (smRNAs) as regulators of histone modifying enzymes, mediating interactions with | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| UNIVERSITY OF ROCHESTER | $99,948 | Grant | Trans-NIH Recovery Act Research Support: This project will accelerate studies proposed related to the epigenetic modification of the apob promoter due to changes in methylation status.-? Funds will provide technical support to carry out the proposed experiments.-? The overall goal is to determin | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| UNIVERSITY OF CHICAGO, THE | $212,294 | Grant | Trans-NIH Recovery Act Research Support: Fluorescence spectroscopy has made myriad essential contributions to our understanding of molecular and cellular biology. Fundamental properties of intrinsic and extrinsic fluorophores probes in biological systems are exquisitely sensitive to the local bi | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| NEW YORK UNIVERSITY (INC) | $154,315 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In order to develop a predictive science of infectious disease, an understanding of the range and intensity of evolutionary forces that shape genomes is required. The genome of an organism, i.e. the coding and non-codi | Health and Human Services, Department of / National Institutes of Health | 2/12/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $205,740 | Grant | Trans-NIH Recovery Act Research Support: The Transgenic Mouse Facility (TMF) was established in 1991 as a centralized core for the efficient production of transgenic animal models for UAB investigators. The shared facility is supported primarily by P30 Grants maintained by University Centers (Co | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $54,400 | Grant | Trans-NIH Recovery Act Research Support: Title: Polymeric Matrices With Defined Cell Adhesion The objective of this administrative supplement request is to accelerate the tempo of scientific research funded under the MERIT award. The long-term objective of this project is to develop material s | Health and Human Services, Department of / National Institutes of Health | 3/09/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $499,800 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cell membrane receptors utilize numerous intracellular second messengers to propagate their signal into and through the cell. Individual receptors can activate many intracellular signaling pathways. An instrument capab | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $27,656 | Grant | Trans-NIH Recovery Act Research Support: The investigations in this proposal are focused on identifying the molecularbasis for the direct and indirect consequences ofVitamin D Receptor (VDR) ablation. VDRknockoutmice develophypocalcemia and secondary hyperparathyroidism which, in turn, leads to | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| WESTERN MICHIGAN UNIVERSITY | $85,377 | Grant | Trans-NIH Recovery Act Research Support: The Michigan Bridges to the Baccalaureate Program (MBBP) will facilitate the transfer of underrepresented minority (URM) science students in community colleges (CCs) to baccalaureate-degree granting programs and inspire and support their progression towar | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $742,627 | Grant | Trans-NIH Recovery Act Research Support: UC Riverside supports a broad range of research including areas of significance to human health such as metabolism, neurobiology, lipid and hormonal signaling, tumor genesis, wounding, nutrition, aging, disease, and pathogenesis. The advent of genomics te | Health and Human Services, Department of / National Institutes of Health | 4/08/2010 |
| SOUTHERN ILLINOIS UNIVERSITY | $141,346 | Grant | Trans-NIH Recovery Act Research Support: Our progress over the last year has prompted us to expand our approach to examine the structure of the ISWI complexes either as free complexes or bound to nucleosomes in ever increasing molecular detail and now have the additional prospect of analyzing tr | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $359,897 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The objective of this proposal is to acquire a non-invasive 3D quantitative molecular imaging system that allows for in vivo, ex vivo and in vitro imaging. The system, called the IVIS Spectrum from Caliper LifeSciences | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| BECKMAN COULTER, INC. | $32,426 | Contract | : J26XPI Avanti Centrifuge, Item# 393127; JA20 Rotor Assembly, Item# 334831 | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $101,500 | Grant | Trans-NIH Recovery Act Research Support: 1. Evaluating the hypothesis that selected GCase-competitive inhibitors can act as pharmacological chaperones in vivo and can correct abnormal GCase function and glucosylceramide (GC) accumulation in visceral organs. These in vivo investigations will test | Health and Human Services, Department of / National Institutes of Health | 3/17/2010 |
| UNIVERSITY OF ILLINOIS | $89,928 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of this project are to understand the purpose of dynamic transcription complexes and the mechanisms that promote dissociation of the employed structures. The general strategy to be used is to focus on intracellular hormone recepto | Health and Human Services, Department of / National Institutes of Health | 1/26/2010 |
| PURDUE UNIVERSITY | $135,175 | Grant | Trans-NIH Recovery Act Research Support: Evolutionary forces are known to drive the fixation of locally adaptive genetic variation within populations, and such variation is thought to be involved in the differential response to disease and pharmacological agents observed in human populations. Na | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| MAYO CLINIC | $98,782 | Grant | Trans-NIH Recovery Act Research Support: This recovery act administrative supplement request to R01 DK57892 is designed to provide a stimulus to the US economy by retaining staff as well as potential long-term opportunities for improving well-being of celiac patients thereby reducing cost to the | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| THE WASHINGTON UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Urinary tract infection (UTI) is a common and costly disease that tends to recur in women despite current antibiotic therapies. Recent studies in a mouse model of UTI suggest that some recurrent UTIs are due to an intracellular reservoir of uropathogenic | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $431,678 | Grant | Trans-NIH Recovery Act Research Support: Individuals with substance abuse disorders often continue to seek and use illicit drugs despite the negative consequences that can arise from this behavior. In order to understand the neural basis of this behavioral inflexibility in the face of negative c | Health and Human Services, Department of / National Institutes of Health | 3/01/2010 |
| APPLIED BIOSYSTEMS, LLC | $109,800 | Contract | : single sale of lab supplies | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $354,177 | Grant | Trans-NIH Recovery Act Research Support: This research explores carbohydrate-protein interactions, providing a basis for better understanding of important processes such as immune system function, organ development, cancer progression and bacterial invasion. Carbohydrates coat the surfaces of h | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| ALA SCIENTIFIC INSTRUMENTS, INC. | $87,420 | Contract | : MEA 256 SYSTEM RETINAL | Health and Human Services, Department of / National Institutes of Health | 10/26/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $88,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis C virus (HCV) is the most common cause of chronic viral hepatitis in the United States, and is a significant cause of morbidity and mortality. The T cell response directed at HCV derived antigens is thought to be important in the pathogenesis of | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $90,284 | Grant | Trans-NIH Recovery Act Research Support: This was an administrative supplement to purchase microscope equipment. This microscope equipment will be used to enhance the progress on two aims of the original grant: 1) to understand the origin of endocytic protein that accumulate at focal adhesions | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| TEXAS A & M UNIVERSITY | $3,529,612 | Grant | National Center for Research Resources, Recovery Act Construction Support: The specific aim of the project is to build out 12,680 sq. ft. of current shell space on the second floor of Texas A&M University's new Interdisciplinary Life Sciences Building. The ILSB was specifically designed to function n as a hub for interdisciplinar... Show more | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $121,619 | Grant | Trans-NIH Recovery Act Research Support: This proposal ?A Novel Ligand for PBR Imaging? is to investigate neuroinflammation in HIV dementia using a novel translocator protein (TSPO) ligand known as [11C]DPA-713. Currently, the ligand used most commonly for evaluating PBR binding is [11C]-R-PK111 | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Hepatitis C virus (HCV) is a major cause of viral hepatitis. There is no effective therapy for most patients. Our long-term objectives are to understand the molecular virology of HCV and translate this knowledge into new antiviral strategies. Like other p | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $101,270 | Grant | Trans-NIH Recovery Act Research Support: In this award application we outline a strategy to identify genes that regulate cancer cell invasion, an early step in cancer metastasis, using the zebrafish. We have shown that zebrafish meltdown (mlt) mutants develop a cancer-like phenotype as a result | Health and Human Services, Department of / National Institutes of Health | 2/16/2010 |
| SEATTLE CHILDREN'S HOSPITAL | $76,010 | Grant | Trans-NIH Recovery Act Research Support: Award provided funding to purchase computer hardware and software to enhance our confocal microscopy capabilities for analyzing the virion binding and receptor interactions in Specific Aims 1 and 2 of the parent grant. Our studies on KSHV entry are depen | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| DUKE UNIVERSITY | $456,500 | Grant | Trans-NIH Recovery Act Research Support: Duke University Medical Center currently has 21 investigators in need of state-of-the-art technology that combines multispectral (brightfield, darkfield, and fluorescence) imaging with flow cytometry. These investigators come from a wide-range of departme | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $93,312 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this proposed administrative supplement is to request additional salary and supply funds for a new recruit to the grant for an accelerated investigation that is in accordance with the original objectives. The ORIGINAL OBJECTIVE is to identi | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| MIAMI UNIVERSITY | $14,681 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to understand the health-related effects of consuming polyphenols found in plant- based foods and beverages. Eating a diet rich in fruits, vegetables, and plant-derived beverages may reduce the risk of diseases that have been linked | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF ROCHESTER | $477,916 | Grant | Trans-NIH Recovery Act Research Support: The University of Rochester Medical Center has targeted X-ray crystallography as an area for strategic development due to its potential for high impact on existing NIH-funded research programs and Centers. A limiting factor in this plan is that our curren | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $975,069 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (14) Stem Cells and specific Challenge Topic, 14-DE-103: Enhancing Human Embryonic Stem (ES) Cell Culture Systems. The overall objective of this proposal is to develop and optimize a feeder-free in vitro cul | Health and Human Services, Department of / National Institutes of Health | 3/09/2010 |
| BECKMAN COULTER, INC. | $69,094 | Contract | : Optima L-100XP Ultracentrifuge (Item# 392052); SW-40Ti Swinging Bucket, Titanium Rotor Package (Item# 331301) | Health and Human Services, Department of / National Institutes of Health | 11/03/2009 |
| UNIVERSITY OF ROCHESTER | $99,875 | Grant | Trans-NIH Recovery Act Research Support: This award will fund the purchase of equipment to enhance cell imaging by upgrading current microscope equipment and contributing to the purchase of a state-of-the-art multispectral imaging flow cytometer. Our long-term aim is to elucidate the cellular | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| CHILDREN'S RESEARCH INSTITUTE | $99,844 | Grant | Trans-NIH Recovery Act Research Support: Regulatory factors sense and maintain nitrogen balance within the mammalian body. These sensors help to trigger the conversion of nitrogenous waste to urea through the urea cycle, and are just beginning to be identified. Our research provides evidence t | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| WAYNE STATE UNIVERSITY (INC) | $212,328 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPION (provided by applicant): Phosphorylation is a ubiquitous post-translational protein modification that plays a critical role in a variety of cellular functions. In fact, various drug targeting the kinases that phosphorylate protein substrates ha | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $381,491 | Grant | Trans-NIH Recovery Act Research Support: IVIS Spectrum Imaging System for the University of South Carolina IVIS Spectrum Imaging System for the University of South Carolina | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| I2S MICRO IMPLANTABLE SYSTEMS, LLC | $121,650 | Contract | : CEREBUS 128 - CHANNEL DATA ACQUISITION SYSTEM; INCLUDES RACK-MOUNTABLE NEURAL SIGNAL PROCESSOR WITH FRONT-END AMPLIFIER / DIGITIZER / FIBER-OPTIC LINK; CABLES, DATA ACQUISITION SOFTWARE, AND 128-CHANNEL NEURAL SIGNAL | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $76,670 | Grant | Trans-NIH Recovery Act Research Support: This application proposes the purchase of a new bone histomorphometry system (OsteoMeasure XP Advanced System) consisting of a digital video analysis system and a fluorescence microscope. This equipment will allow the PI of this application, Dr. Bellido, | Health and Human Services, Department of / National Institutes of Health | 2/22/2010 |
| UNIVERSITY OF MASSACHUSETTS | $238,157 | Grant | Trans-NIH Recovery Act Research Support: The rough endoplasmic reticulum is a major site of protein synthesis in eukaryotic cells, serving as the entry point for the secretory pathway, and the biosynthetic site for the majority of cellular integral membrane proteins. The long-term goal of the pa | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $94,961 | Grant | Trans-NIH Recovery Act Research Support: We propose to use FACS analysis to quantify immune populations in adipose tissue. This is in addition to the parent proposal in which we will quantify macrophage populations using immunohistochemistry. The supplemental funds will allow us to purchase a | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The proposed work in this shared instrumentation grant application comes from many of the clinical and/or translational research programs ongoing at the Cleveland Clinic, a major research institution in the northeast Ohio region. The purpose of this appli | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $139,092 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of my laboratory is to understand how new genes with novel functions originate and how these molecular innovations contribute to the survival, adaptation, and evolution of organisms. Gene duplication is wildly regarded as the prima | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| UNIVERSITY OF UTAH, THE | $168,650 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Breast cancer is a heterogeneous disease. A significant challenge in the development and testing of new therapies is determining which tumors a drug will target. Initial studies with a novel class of small molecule inh | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $6,089,770 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes a vital renovation that would allow advanced MRI research to proceed, grow, and flourish at this center. The BMRC currently includes 3 MRI scanner bays which house one GE 3.0 Tesla (T) and one GE 1.5T magnet. A 2nd 3.0T GE scanner | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $90,097 | Grant | Trans-NIH Recovery Act Research Support: Centrosomes are microtubule-organizing centers (MTOCs) consisting of two centrioles surrounded by pericentriolar material. Accurate centrosome duplication precisely once per cell cycle is required for formation of a bipolar mitotic spindle, the apparatus | Health and Human Services, Department of / National Institutes of Health | 3/24/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $74,997 | Grant | Trans-NIH Recovery Act Research Support: The Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to characterize the natural history of the different phenotypes of nonalcoholic fatty liver | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $106,029 | Grant | Trans-NIH Recovery Act Research Support: Molecular-motor based transport of organelles is common, and is required for cellular health and vitality; impared transport underlies a variety of neurodegenerative diseases. Much of this transport is bi-directional, with average transport of a specific | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $359,897 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): An IVIS Spectrum imaging system will be purchased for use in a shared small animal imaging facility at the Albert Einstein College of Medicine. The IVIS imaging systems allow the real time imaging of small animals expr | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $54,361 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to request funds for a study coordinator to assist the PI with the significant administrative activities resulting from the parent grant, G?Genotype-phenotype relationships in auditory neuropathy.G? To create a full-time | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF SOUTH ALABAMA | $397,435 | Grant | Trans-NIH Recovery Act Research Support: THIS PROPOSAL SEEKS SUPPORT UNDER THE NCRR SHARED INSTRUMENTATION GRANT PROGRAM TO OBTAIN A NIKON A1-R-SI LASER SCANNING CONFOCAL MICROSCOPE TO INITIALLY RESEARCH IN THE AREAS OF CARDIOVASCULAR BIOLOGY AND VASCULAR REMODELING, PULMONARY PHYSIOLOGY, AND CA | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| UNIVERSITY OF ROCHESTER | $370,097 | Grant | Trans-NIH Recovery Act Research Support: This is an award to purchase an IVIS Spectrum Multimodal (multispectral bioluminescence and fluorescence) Imaging instrument. The shared instrument will compliment and boost the extensive imaging resources available to University of Rochester Medical Cent | Health and Human Services, Department of / National Institutes of Health | 6/03/2010 |
| BOSTON MEDICAL CENTER CORPORATION | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This project addresses the broad Challenge Area (15) G?Translational ScienceG?, and the Specific Challenge Topic 15-OD(ORDR)-101, G?Pilot projects for prevention, early detection and treatment of rare diseasesG?. In this project, we will develop a G?secon | Health and Human Services, Department of / National Institutes of Health | 5/10/2010 |
| TRUSTEES OF GRINNELL COLLEGE, THE | $373,647 | Grant | Trans-NIH Recovery Act Research Support: We study positive allosteric modulation of neuronal nicotinic acetylcholine receptors (nAChRs). These ligand-gated ion channels are the seat of nicotine addiction and are implicated in a wide range of other neurological disorders. Allosteric modulation | Health and Human Services, Department of / National Institutes of Health | 4/19/2010 |
| MOLECULAR EXPRESS INC | $197,977 | Grant | Trans-NIH Recovery Act Research Support: The Company has been developing a new approach to immunization for herpes simplex virus type 2 (HSV2) infections that combines a unilamellar liposome carrier with a recombinant protein system that is capable of being engineered to express selected antigen | Health and Human Services, Department of / National Institutes of Health | 5/11/2010 |
| UNIVERSITY OF CONNECTICUT | $229,500 | Grant | Trans-NIH Recovery Act Research Support: A better understanding of the role of prostaglandins in the PTH-regulation of bone gain and loss could have an important impact on our understanding of general mechanisms that drive new bone formation, laying the basis for future development of new agents | Health and Human Services, Department of / National Institutes of Health | 4/12/2010 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $91,871 | Contract | : MSKCC has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas project. Specifically this award is to fund the provision of breast cancer specimens (N=55). These are predominantly retrospective specimens. These cases are | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $45,727 | Grant | Trans-NIH Recovery Act Research Support: The award will be used to purchase equipment necessary to read ELISAs, as well as BCA assays for Western blotting, as part of the biochemical analyses proposed in Specific Aims 3 and 4 of the parent grant. | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $150,000 | Grant | Trans-NIH Recovery Act Research Support: ChiLDREN is the Childhood Liver Disease Research and Education Network. At our site, Johns Hopkins University, we are actively recruiting and enrolling into the studies which compose ChiLDREN, including PROBE, START, BASIC, LOGIC, and MITOHEP. At the pres | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| CARNEGIE INSTITUTION OF WASHINGTON | $161,402 | Grant | Trans-NIH Recovery Act Research Support: Steroids are universal signaling molucules in all multicellular organisms and are critically important for both plant growth and human health. Understanding the mechanisms of steroid function in diverse organism will reveal conserved mechanisms and provid | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $181,873 | Grant | Trans-NIH Recovery Act Research Support: The research addresses diabetic retinopathy, the most common complication of diabetes. The research seeks to identify processes that are active early in diabetic retinal vessels, so as to develop the best drug strategy for prevention of the late damage. | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $154,000 | Grant | Trans-NIH Recovery Act Research Support: Over the past 20 years we developed Blood Glucose Awareness Training (BGAT), an 8-session intervention that focuses on preventing extreme blood glucose (BC), and better detection and management of extreme BG when it occurs. BGAT has broad benefits: reduc | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $174,781 | Grant | Trans-NIH Recovery Act Research Support: The aim of these studies is to understand the precise signaling mechanisms which regulate calcium release from inositol 1,4,5- trisphosphate receptor channels during apoptosis, with the ultimate goal of identifying novel targets for therapeutic interventi | Health and Human Services, Department of / National Institutes of Health | 3/10/2010 |
| STARKS ASSOCIATES, INC. | $70,000 | Contract | : This contract action provides compound synthesis support for the NCI American Recovery and Reinvestment Act (ARRA) project entitled Cancer Pathway Dissection and Combination Therapies project. The NCI wishes to build a specific targeted library or librar | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| HYPER TECH RESEARCH, INC. | $2,999,547 | Grant | Trans-NIH Recovery Act Research Support: Over the past several years, the price and life cycle cost of 1.5T and 3.0T MRI systems have been increasing due to a dramatic increase in helium cost, and there is a critical need to avoid further increases. This is particularly troubling to the medical | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| CARL ZEISS MICROIMAGING, INC. | $26,823 | Contract | : Laboratory Equipment | Health and Human Services, Department of / National Institutes of Health | 4/05/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $76,776 | Grant | Trans-NIH Recovery Act Research Support: The PHD finger is a signature chromatin-associated protein motif, mutations in which are associated with cancers, immunodeficiency syndromes, and other genetic disorders. Our long-term goal is to develop a comprehensive molecular understanding of how PHD | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $5,970 | Contract | : NIDA/Addition Res Center, Baltimore, Marland. Refig Chromatg 45.4 CUFT 115V and a Feezer | Health and Human Services, Department of / National Institutes of Health | 2/25/2010 |
| MCLEAN HOSPITAL CORPORATION, THE | $499,016 | Grant | Trans-NIH Recovery Act Research Support: This proposal is to fund a complete refurbishment of the McLean Hospital 4 Tesla Varian Whole Body Multinuclear Magnetic Resonance Imaging system. This instrument has been extremely productive since it was first installed in May, 2001 both as a developmen | Health and Human Services, Department of / National Institutes of Health | 3/18/2010 |
| NEW YORK UNIVERSITY | $74,613 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides for one postdoctoral scientist to accelerate the pace of the research. The proposed methods, conceptual framework, and findings can provide the basis for assessing flexibility in children with motor impairments and for tracking im | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $105,520 | Grant | Trans-NIH Recovery Act Research Support: Under normal conditions, most T lymphocytes are made in the thymus. However, the thymus degenerates with age, beginning around puberty. Because output of new Tcells from the thymus is proportional to its mass, age-related thymic atrophy results in a prog | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $969,931 | Grant | Trans-NIH Recovery Act Research Support: This application is focused on the design, synthesis and evaluation of potential biological probes and treatment agents for alcohol dependence based on their actions on the nociceptin (NOP) receptor. We seek to identify compounds thai act as partial agoni | Health and Human Services, Department of / National Institutes of Health | 5/22/2009 |
| YALE UNIVERSITY | $371,314 | Grant | Trans-NIH Recovery Act Research Support: The central goal of the Yale Center of Excellence in Molecular Hematology is to facilitate ongoing collaborative research designed to understand and manipulate gene expression and regulation related to the self-renewal, proliferation and differentiation o | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $14,287,680 | Grant | National Center for Research Resources, Recovery Act Construction Support: Funding for in-vivo based research at UCSD has doubled over the past decade while the primary species used (mice) has almost tripled during this same time period. Cleanliness achieved from adequate sanitation and sterilizationon of caging and equipment rema... Show more | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF FLORIDA | $99,471 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to elucidate the molecular determinants of the regulation of corneal epithelial cell phenotype. It is now apparent that corneal epithelial cell phenotype must be held in check by constant transcriptional maintenance, | Health and Human Services, Department of / National Institutes of Health | 1/29/2010 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $231,447 | Grant | Trans-NIH Recovery Act Research Support: We aim to synthesize marine metabolites with potential clinical applications. The focus of this research is the synthesis of biologically significant and synthetically challenging natural pyrrole-imidazole alkaloids, in particular, massadine, a newly disc | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $96,518 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is the development of high-throughput fluorescent assay for measurement of reduced folate pools in biological samples. Such an assay is an important research tool for biomedical studies relevant to folate metabolism and certai | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| TEXAS A & M UNIVERSITY SYSTEM HEALTH SCIENCE CENTER RESEARCH | $157,837 | Grant | Trans-NIH Recovery Act Research Support: Retinoic acid (RA), the active metabolite of vitamin A, is an important regulator of cell proliferation, embryonic/fetal development, and adult homeostasis. Mice that are deficient for Raldh2, an enzyme critically involved in the synthesis of RA from reti | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $293,496 | Grant | Trans-NIH Recovery Act Research Support: Bacterial pneumonia continues to be a leading cause of death and warrants improved treatment strategies. Recruitment of neutrophils into the lungs is one of the most important defense mechanisms in the initial host defense against bacterial infection. How | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $6,400 | Grant | Trans-NIH Recovery Act Research Support: Inadequate cell mass is common to both type 1 and type 2 diabetes. Our long-term research goal is to understand the signals that influence -cell growth, as a step towards regeneration of -cell mass in diabetes patients. Surprisingly little is known about | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $299,999 | Grant | Trans-NIH Recovery Act Research Support: Longitudinal Assessment of Bariatric Surgery (LABS) consortium was established in 2003 and was conceived to address important issues in bariatric surgery and metabolism in the obese and morbidly obese. LABS explores relationships of patient characteristic | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| ACTIGRAPH L.L.C. | $358,456 | Contract | : RECOVERY-Biomarker Based Validation of Diet and Physical Activity Assessment Tools in Existing Cohorts | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| YALE UNIVERSITY | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The challenge area (15-DK-103) is the translation of new molecules and pathways involved in pathogenesis of diseases of interest to NIDDK into potential therapies, diagnostics, or research tools. The specific challenge topic is the examination of the ther | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| UNIVERSITY OF CHICAGO, THE | $105,409 | Grant | Trans-NIH Recovery Act Research Support: Our understanding of reaction mechanisms in biological systems at the molecular level is presently based largely on knowledge of static, chemically- or physically-trapped structures obtained by high resolution X-ray crystallographic and NMR techniques. Ho | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $79,750 | Grant | Trans-NIH Recovery Act Research Support: Cells start migration by generating protrusions, which require the dynamic assembly of a branched actin network and remodeling of the plasma membrane. How actin dynamics and membrane activities are coordinated during cell migration is a fundamental questi | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The aim of this proposal is to upgrade the gradient/shim system on our human 4T/90cm Varian/Siemens MR scanner. This 4T magnet was installed in 1998, its console will be upgraded this year, but the current gradient/shim system will be the limiting factor | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| ANC RESEARCH & DEVELOPMENT, LLC | $666,021 | Contract | : Leica TCS SP5 II AOBS Spectral Confocal and MP System | Health and Human Services, Department of / National Institutes of Health | 2/18/2010 |
| A-TEK INC | $927,981 | Contract | : NOTE: This project was funded on 11/05/09 and began 11/16/09. There has been a follow-on task order awarded to continue support beyond 07/15/10; which was completed as of 09/30/10. The A-TEK Team was awarded the requirement to provide support for the US | Health and Human Services, Department of / National Institutes of Health | 11/05/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: HHRH is an autosomal recessive disorder. In a large Bedouin kindred affected by HHRH, we recently described a homozygous frameshift mutation (c.228del) in SLC34A3, the gene encoding NaPi-llc (Am J Hum Genetics, 78:179-192, 2006). Further analysis of this | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| NEW YORK UNIVERSITY (INC) | $9,339,773 | Grant | Trans-NIH Recovery Act Research Support: New York University Langone Medical Center School of Medicine (NYUSoM) is a leading center of excellence in health care, biomedical research, education, and public service in New York City. The proposed facility to be improved through the requested funds | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $99,740 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will provide funds for the addition of necessary equipment and personnel in our laboratory to increase the pace of research leading to a cure for sickle cell disease. Funds for the purchase of a real-time quantitative RT-PCR | Health and Human Services, Department of / National Institutes of Health | 1/18/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,221 | Grant | Trans-NIH Recovery Act Research Support: A hallmark of Type 2 diabetes is impaired insulin secretion from beta cells of the islets of Langerhans. Type 1 diabetes is characterized by autoimmune attack on beta cells and subsequent loss of insulin secretion. A promising treatment for type 1 diabete | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $94,714 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cyclic peptides have been explored as ligands against a wide variety of biological targets. They are relatively easy to synthesize, and, at the same time, exhibit a degree of complexity unrivaled by most other classes | Health and Human Services, Department of / National Institutes of Health | 1/21/2010 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $34,521 | Grant | Trans-NIH Recovery Act Research Support: Support for three undergraduates to work on summer projects on hepatocelluar carcinoma (HCC). They worked on proteomic and genomic data to construct a molecular profile of HCC and the steps in the progression from hepatitis C virus infection to cirrhosis | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: The advent of induced pluripotent stem cell (iPS cell) technology offers new and profound opportunities to study human disease and to develop cellular therapies targeted to a specific cell population. Our understanding of many genetic diseases is limited | Health and Human Services, Department of / National Institutes of Health | 4/07/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $103,093 | Grant | Trans-NIH Recovery Act Research Support: Mucosal organs such as the intestine and lung are highly vascular organs with extensive metabolic demands. Epithelial cells which line the intestine function to orchestrate a multitude of mucosal responses, and given their anatomic location, are primary t | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| CDW GOVERNMENT, INC. | $99,183 | Contract | : Purchase of information technology commercial items to improve agency operations or to fulfill agency requirements. | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $71,010 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award provides supplemental funds for an NIH funded grant to purchase a multi-electrode electrophysiological system for in-vivo recording of brain neuronal activity. This state-of-the-art instrumentation will allow us to conduct new studies that | Health and Human Services, Department of / National Institutes of Health | 2/10/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $175,442 | Grant | Trans-NIH Recovery Act Research Support: This project titled 'Anachem Lipidic Cubic Phase Crystallization Robot' is to purchase a lipidic cubic phase robot equipment to facilitate structure determination of membrane proteins in their lipid environments. Membrane proteins constitute about 30% o | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| FIG LEAF SOFTWARE INC. | $5,332 | Contract | : Forty hours of software configuration and training for the National Heart, Lung and Blood Institute, at a GSA hourly rate for Interactive Media Programmer of $133.31, for a contract total of $5,332.40. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $105,330 | Grant | Trans-NIH Recovery Act Research Support: The research outlined will develop a well-defined environment for culturing induced pluripotent stem (iPS) cells, thereby advancing the field of human stem cell biology. Human embryonic stem (hES) cells are being studied as potential source of cells for | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $392,535 | Grant | Trans-NIH Recovery Act Research Support: The goal of this award is to add a copper-64 (64Cu) targetry and handling system to a RDS 111 biomedical cyclotron to enable routine production of the radionuclide 64Cu for in vivo molecular imaging studies. The cyclotron and the proposed targetry system | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF IOWA, THE | $120,763 | Grant | Trans-NIH Recovery Act Research Support: Sexual reproduction is prevalent in eukaryotes and plays a key role in their fitness and survival. Asexual species often arise, but regularly go extinct due, in part, to deleterious mutation accumulation and the inability to adapt to changing environments | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| MAXWELL SENSORS INC. | $2,802,966 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to develop Barcoded Magnetic Beads for Rapid Tests of MRSA and Respiratory Viral Panels. This Barcoded Magnetic Beads, utilizing a digital technology instead of conventional analog methodology, offers unmatched accuracy, excell | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| ASTERAND INC. | $124,650 | Contract | : Asterand, Inc. has been awarded a contract to provide tumor types to the NCI for the Cancer Genome Atlas (TCGA) project. Specifically, this award is to fund the provision of 200 tissues from 100 Stomach Adenocarcinoma cases. The biospecimens from these | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The proposed upgrade of the 7 Tesla imaging resource will substantially impact the fundamental understanding, early diagnosis, and development of novel therapies for host of human disease. | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| SPAULDING REHABILITATION HOSPITAL (SRH) VOLUNTEER SERVICES, | $469,601 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this protocol is to investigate the central nervous system dysfunction that is associated with chronic pelvic pain and also a possible novel treatment using a neuromodulatory tool - transcranial direct current stimulation (tDCS) - for this | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $205,450 | Grant | Trans-NIH Recovery Act Research Support: Autophagy is a process that is involved in degradation of long-lived proteins and removal of damaged organelles. Autophagy is generally thought of as a survival process that is upregulated by the cells during periods of starvations, but recent studies ha | Health and Human Services, Department of / National Institutes of Health | 1/28/2010 |
| SAIC FREDERICK, INC | $9,500,000 | Contract | : Molecular Characterization & Assay Development DCTD Utilization of ARRA (Stimulus) Resources, NCIG??s Division of Cancer Treatment and Diagnosis (DCTD), under the umbrella of the American Recovery and Reinvestment Act of 2009 (ARRA), is requesting support | Health and Human Services, Department of / National Institutes of Health | 2/04/2010 |
| JACOBS PROJECT MANAGEMENT CO. | $5,301,667 | Contract | : As Construction Quality Manager (CQM), Jacobs will perform construction management services for the Porter Neuroscience Research Center (PNRC) - Phase II project. CQM services will be provided during pre-design, design, bidding, construction and project c | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| UNIVERSITY OF LOUISVILLE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Project description: 1) Performing computer simulations of the EPO dosing algorithms (aim 3 - parent grant). 2) Developing computer software to implement the EPO dosing algorithms for in-center use (aim 4 - parent grant). 3) Developing computer software | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,000 | Grant | Trans-NIH Recovery Act Research Support: End stage renal disease (ESRD) is an important public health issue. Based on 2005 USRDS data ESRD patients utilize 19.2% of medicare spending (21.3 billion dollars). Diabetic nephropathy and glomerulonephritis contributes about 56.5% of the incident patie | Health and Human Services, Department of / National Institutes of Health | 1/16/2010 |
| UNIVERSITY OF WASHINGTON | $97,487 | Grant | Trans-NIH Recovery Act Research Support: Funds requested by this administrative supplement will be applied to employ new personnel and purchase equipment that will address the original scope of the peer-reviewed activities and aims approved within the parent grant. Hiring of two graduate student | Health and Human Services, Department of / National Institutes of Health | 3/08/2010 |
| CHILDREN'S HOSPITAL ASSOCIATION, THE | $153,974 | Grant | Trans-NIH Recovery Act Research Support: In this application, the Principal and Co-investigators propose the development of a coordinated and integrated 'Rare Liver Disease Network' (RLDN) as a Rare Diseases Clinical Research Center in response to NIH RFA RR 03-008. The RLDN will focus on invest | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| THE JACKSON LABORATORY | $725,671 | Grant | Trans-NIH Recovery Act Research Support: The mammalian genome is a dynamic system that varies spatially in its organization and expression and temporally in its evolution and inheritance. Using a team of computational biologists, molecular biologists and geneticists, we are studying genome dynam | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| UNIVERSITY OF FLORIDA | $437,959 | Grant | Trans-NIH Recovery Act Research Support: Stroke is the leading cause of disability in the U.S. More than 4.5 million stroke survivors live in the community with functional limitations requiring the assistance of family caregivers. Stroke occurs suddenly, is unpredictable, life-disrupting, and do | Health and Human Services, Department of / National Institutes of Health | 3/15/2010 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $7,030,924 | Grant | National Center for Research Resources, Recovery Act Construction Support: Building on our strengths in rheumatology, autoimmunity and immunology, as well as our unique rural and American Indian patient populations, the Oklahoma Medical Research Foundation (OMRF) requested funds to build-out approximimately two floor of shell spac... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $501,011 | Grant | Trans-NIH Recovery Act Research Support: Longitudinal Assessment of Bariatric Surgery (LABS) consortium was established in 2003 and was conceived to address important issues in bariatric surgery and metabolism in the obese and morbidly obese. LABS explores relationships of patient characteristi | Health and Human Services, Department of / National Institutes of Health | 3/29/2010 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $234,765 | Grant | Trans-NIH Recovery Act Research Support: The cell envelope of Gram-negative bacteria contains two membranes, inner (IM) and outer (OM), and the aqueous compartment termed the periplasm that is located between the membranes. The long term goal of this grant has always been to understand the mecha | Health and Human Services, Department of / National Institutes of Health | 2/17/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $466,012 | Grant | Trans-NIH Recovery Act Research Support: We are requesting funding for a state-of-the-art matrix-assisted laser desorption ionization time-of-flight/time- of-flight (MALDI-TOF/TOF) mass spectrometer to be utilized for imaging by mass spectrometry (ImMS) of thin tissue sections. An exciting new a | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $130,359 | Grant | Trans-NIH Recovery Act Research Support: This proposal is for the purchase of a Moor Instruments Vascular Assessment System (VAS), which will serve 7 NIH-funded research groups. The VAS is an integrated laser Doppler imaging (LDI) device that will replace our first generation Moor LDI system, w | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $312,428 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to develop more effective therapeutic regimens for the treatment of colorectal cancer. These regimens will target not only malignant epithelial cells of the tumor, but also the cancer stem cells responsible for tumor re | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $79,000 | Grant | Trans-NIH Recovery Act Research Support: Additional support for the purchase of a fluorescence microscope and a cell counter for investigations with cultured cells in which we use fluorescent probes and reporters (e.g. green fluorescent protein) to follow the activity of various gene manipulatio | Health and Human Services, Department of / National Institutes of Health | 1/07/2010 |
| RHODE ISLAND HOSPITAL | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Obesity-related type 2 diabetes mellitus, characterized by insulin resistance, currently affects 150 million people worldwide. In the insulin resistant diabetic state, blood glucose levels are elevated due to increased glucose production from the liver (m | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| YALE UNIVERSITY | $81,045 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In adult, reproductively active females, there is a continued increase in prevalence and propagation of metabolic disorders, such as obesity and type II diabetes. Beyond the harmful effects of these disorders on the ad | Health and Human Services, Department of / National Institutes of Health | 3/11/2010 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $101,782 | Grant | Trans-NIH Recovery Act Research Support: TRPM7 was the first identified ion channel to contin its own kinase domain. Excessive TRPM7 channel activity has been implicated in neuronal cell death during ischemia, but the mechanisms by which the channel is regulated are not well understood. Prelim | Health and Human Services, Department of / National Institutes of Health | 2/24/2010 |
| UNIVERSITY OF UTAH, THE | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: DESCRIPTION (provided by applicant): Advances in medicine depend upon research and technology development at the interfaces of the physical and life sciences. Chemistry is essential to understanding life processes at the molececular level, and new physics-b... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| CORNELL UNIVERSITY, INC | $171,005 | Grant | Trans-NIH Recovery Act Research Support: This application requests funds for state-of-the-art Light Scattering (LS) devices for the characterization of macromolecular size, shape, oligomeric state and solution behavior. The instrumentation will consist of a Wyatt Technology Corporation DAWN HELE | Health and Human Services, Department of / National Institutes of Health | 2/20/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $34,938 | Grant | Trans-NIH Recovery Act Research Support: This application addresses NOT-OD-09-056: Notice of Availability of Recovery Act Funds for Administrative Supplements. PI will be mentoring Dr. Vuppalanchi to conduct a study to investigate the potential involvement of hepatic microRNA (mi-RNA) in the reg | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $549,708 | Grant | Trans-NIH Recovery Act Research Support: A new paradigm to treat gut bacteria-associated sepsis is urgent for persons who have radiation-associated damage in gastrointestinal system caused by terrorist acts or accidental exposure. Antibiotics are effective against these infections, however; anti | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $219,750 | Grant | Trans-NIH Recovery Act Research Support: This one year ARRA award provided us with bridge funding to continue a project that has been ongoing in our laboratory for over 10 years. The main goals of this project have been to: determine how the CFTR channel (i.e., the ion channel that is defective | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| SPARKS PERSONNEL SERVICES, INC. | $3,802 | Contract | : other management services | Health and Human Services, Department of / National Institutes of Health | 1/11/2010 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $13,533,254 | Grant | National Center for Research Resources, Recovery Act Construction Support: This proposal by Tulane University is a request for funds to remodel select biomedical research laboratories in the J. Bennett Johnston Health and Environmental Research Building (JBJ building) on our Health Science Center camampus. The main objective of th... Show more | Health and Human Services, Department of / National Institutes of Health | 3/25/2010 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $66,011 | Contract | : 1-ARRAY SYSTEM + HTF $57,255.35 1-ASSAY READER WASH STATION $8,755.55 | Health and Human Services, Department of / National Institutes of Health | 2/26/2010 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $3,137 | Contract | : 1-Cool Lab All Refrigerator 20CU FT 120V; catalog #3766A $1,977.10 1-Refrigerator /Freezer 5.6 CU FT; catalog #3750 $1,160 | Health and Human Services, Department of / National Institutes of Health | 1/12/2010 |
| LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY | $84,744 | Grant | Trans-NIH Recovery Act Research Support: The equipment supplement awarded under the American Recovery and Reinvestment Act funded the purchase of an Agilent Bravo robotic device for the Bottini lab and a used SpectraMax Gemini XS Microplate reader, used Beckman J2MI centrifuge and a used GelDoc- | Health and Human Services, Department of / National Institutes of Health | 1/30/2010 |
| MICHIGAN STATE UNIVERSITY | $11,993 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award provides an administrative summer research grant to an ongoing research project. The objective of the parent project is to test the hypothesis that the ribosome plays a central role in the initiation and integration of stress respo | Health and Human Services, Department of / National Institutes of Health | 5/21/2010 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $37,125 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Almost all cell surface and secreted proteins are modified by covalently-linked carbohydrate moieties and the glycan structures on these so-called glycoproteins have been implicated as essential mediators in processes | Health and Human Services, Department of / National Institutes of Health | 4/23/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $34,000 | Grant | Trans-NIH Recovery Act Research Support: This award was to purchase a multi-well plate scintillation counter and luminometer to assist us in our GST-pullldown protein-protein interaction assays and in our cell transfection assays. | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| LIFE MEASUREMENT, INC. | $99,675 | Contract | : ONE PEA POD SYSTEM | Health and Human Services, Department of / National Institutes of Health | 11/12/2009 |
| THE VANDERBILT UNIVERSITY | $39,500 | Grant | Trans-NIH Recovery Act Research Support: Zucker diabetic fatty (ZDF) rats, an animal model of human type 2 diabetes, have a blunted response to hyperglycemia with a failure to suppress net hepatic glucose production and increase glucose flux to glycogen, which are associated with a failure to st | Health and Human Services, Department of / National Institutes of Health | 2/02/2010 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $110,437 | Grant | Trans-NIH Recovery Act Research Support: We have recently discovered a novel mitotic histone kinase, haspin, that has homologs in diverse eukaryotes. Haspin phosphorylates Thr-3 in the N-terminal tail of histone H3. In human cells, H3 Thr-3 phosphorylation is first detected on chromosome arms in | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $99,500 | Grant | Trans-NIH Recovery Act Research Support: Thyroid hormone receptors (TRs) are ligand-dependent, transcriptional regulators of metabolism. TRs repress gene expression in the absence of hormone, which is paradigmatic for other nuclear receptors (NRs) that function as repressors in the unliganded st | Health and Human Services, Department of / National Institutes of Health | 1/15/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $99,710 | Grant | Trans-NIH Recovery Act Research Support: The Biochemical Basis for the Mechanics of Cytokinesis This grant supports our work on the mechanics of cell division particularly focusing on how forces affect the biochemistry of actin crosslinking proteins. We are elucidating the signaling pathways tha | Health and Human Services, Department of / National Institutes of Health | 1/14/2010 |
| NOVA SOUTHEASTERN UNIVERSITY, INC. | $453,430 | Grant | Trans-NIH Recovery Act Research Support: There are many uncertainties about the brain angiotensin system and its functionality is controversial. However, it is generally accepted that brain angiotensin causes hypertension and other cardiovascular disorders. With the recognition of functionality | Health and Human Services, Department of / National Institutes of Health | 2/23/2010 |
| UNIVERSITY OF NEW MEXICO | $212,968 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement, is to assess the biological validity of a novel hypothesis that, in the absence of genetic exchange, a population should adapt itself to extinction as the result of a strong evolutionary asymmetry in the mutatio | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| WAYNE STATE UNIVERSITY (INC) | $304,000 | Grant | Trans-NIH Recovery Act Research Support: This project provides administrative supplemental funding for eligible grantees from these programs (25 CNP-U01, 7 MI/CCP-U54, 8PNRP-U01 grants) to support a community health educator (CHE) at their respective sites. The roles of the CHE may include: 1) | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $7,214 | Contract | : Laboratory Equipment and supplies for the National Institute on Deafness and other Communication Disorders | Health and Human Services, Department of / National Institutes of Health | 1/31/2010 |
| FISHER SCIENTIFIC COMPANY L.L.C. | $15,252 | Contract | : Laboratory Equipment and Supplies. | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $14,830,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: Penn State proposes to build a new 1,858 m2 (20,000 GSF) animal biosafety level three (ABSL-3) building. This facility is critically needed to support expanding research programs in emerging pathogens, zoonoses, vector borne d diseases, the host pathogen in... Show more | Health and Human Services, Department of / National Institutes of Health | 3/04/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $300,544 | Grant | Trans-NIH Recovery Act Research Support: Title: Engineering Skeletal Muscle with Biodegradable Hydrogels. Skeletal muscle tissue is often required in reconstructive craniofacial surgery, and the long-term goal of the applicants? research is to regenerate functional craniofacial skeletal muscle. | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $94,092 | Grant | Trans-NIH Recovery Act Research Support: Vitamin A and its active metabolite, retinoic acid (RA), affect the immune system in multiple ways. Our research is focused on the ability of retinoids to work together with co-stimulatory molecules, of both endogenous and exogenous origin, to promote str | Health and Human Services, Department of / National Institutes of Health | 2/19/2010 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $197,056 | Grant | Trans-NIH Recovery Act Research Support: Corneal erosions/abrasions ranging from superficial defects to full thickness epithelial lesions are found in 50% of diabetic patients, and this condition is termed diabetic keratopathy. Moreover, difficulty with corneal re-epithelialization and persisten | Health and Human Services, Department of / National Institutes of Health | 2/01/2010 |
| MEHARRY MEDICAL COLLEGE | $99,823 | Grant | Trans-NIH Recovery Act Research Support: Research data indicates that nitric oxide (NO) mediated stomach smooth muscle relaxation is higher in healthy females than in age matched healthy male rats and a reduction of this system leads to severe stomach emptying problems in diabetic females only. | Health and Human Services, Department of / National Institutes of Health | 1/27/2010 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $423,500 | Grant | Trans-NIH Recovery Act Research Support: Trypanosomes and related protozoa cause a variety of debilitating diseases in the tropics including Human African Sleeping Sickness, Chagas Disease and various forms of Leishmaniasis. In the mammalian hosts, regulated gene expression is determined primar | Health and Human Services, Department of / National Institutes of Health | 5/04/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $34,669 | Grant | Trans-NIH Recovery Act Research Support: Title: SIGNALING TO PIAS1 TO REGULATE IMMUNE RESPONSES; This administrative supplement is to support NIH R01 award number 3R01GM085797. The request is to cover costs that are associated with purchasing equipment: 1) a sonicator with a probe, to be used to | Health and Human Services, Department of / National Institutes of Health | 4/09/2010 |
| DUKE UNIVERSITY | $732,237 | Grant | Trans-NIH Recovery Act Research Support: Explore and establish a web service or platform that serves as a common user interface. Current software was developed indepently by various labs using different third party libraries and coding languages ( C++, Java, Matlab and R) and using a variety of | Health and Human Services, Department of / National Institutes of Health | 4/23/2010 |
| BIO-RAD LABORATORIES, INC. | $20,058 | Contract | : LABORATORY SUPPLIES | Health and Human Services, Department of / National Institutes of Health | 5/13/2010 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $17,630 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent grant research is to investigate the potential impact of low levels of vanadium containing air pollutant particles on the innate immune responses to gram positive bacterial infections of the airway using a mouse animal ,odel. The i | Health and Human Services, Department of / National Institutes of Health | 6/09/2010 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $28,500 | Grant | Trans-NIH Recovery Act Research Support: This grant provided an equipment purchase to improve slice visualization and allow more stable long-term electrophsiolocal recordings for the project, Neuropeptide Y and the Control of Catecholamine Secretion from the Adrenal Gland. | Health and Human Services, Department of / National Institutes of Health | 4/09/2010 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $847,291 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this research is a detailed understanding of herpesvirus DNA polymerases and drugs that target them. These enzymes, which include a catalytic subunit (Pol) and an accessory subunit that stimulates long-chain DNA synthesis, are | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| COMPUTERBILITIES, INC | $36,043 | Contract | : Recovery - Dell computers and accessories | Health and Human Services, Department of / National Institutes of Health | 6/07/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $444,736 | Grant | Trans-NIH Recovery Act Research Support: Integrated system for phenotyping energy balance and metabolism in animal models Energy balance, the relationship between energy consumed (through food and drink) and energy expended (through activity and metabolic rate), plays a central role in many dis | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| UNIVERSITY OF WISCONSIN SYSTEM | $766,050 | Grant | Trans-NIH Recovery Act Research Support: This proposal is directed to the Recovery Act Limited Competition, High-End Instrumentation Grant Program (S10) Program Announcement (PA) Number: PAR-09-118. Funds are requested to upgrade the Bruker 750 MHz NMR spectrometer located in the National Magnet | Health and Human Services, Department of / National Institutes of Health | 4/08/2010 |
| DANA-FARBER CANCER INSTITUTE, INC. | $799,185 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to build an infrastructure to discover novel viruses associated with human cancer from next-generation sequencing data, using a sequence-based computational subtraction approach that we developed. This proposed project responds to the ARRA Res | Health and Human Services, Department of / National Institutes of Health | 5/03/2010 |
| CDW GOVERNMENT LLC | $170,890 | Contract | : Award was for the purchase of information technology commercial items to improve agency operations or to fulfill agency requirements. | Health and Human Services, Department of / National Institutes of Health | 4/07/2010 |
| ANN & ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO | $140,854 | Grant | Trans-NIH Recovery Act Research Support: Children's Memorial Hospital is a leading clinical center in the ChiLDREN consortium, and its predecessors BARC and CLiC. The project to which the requested supplement would contribute involves our ongoing contributions to achieving the goals of the ChiL | Health and Human Services, Department of / National Institutes of Health | 2/05/2010 |
| SAN DIEGO STATE UNIVERSITY | $327,773 | Grant | Trans-NIH Recovery Act Research Support: It is the over all goal of this project to develop a novel chemotherapeutic agent based on the San A scaffold. It is our hypothesis that analogs of San A with even greater potency and selectively can be synthesized by modifying key structural features ide | Health and Human Services, Department of / National Institutes of Health | 5/24/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $998,778 | Grant | Trans-NIH Recovery Act Research Support: The liver is the main site of intermediary metabolism of amino acids, carbohydrates, lipids and xenobiotics. Metabolic pathways, especially those of xenobiotic compounds, are highly species specific and can vary even between individuals of the same specie | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $94,194 | Grant | Trans-NIH Recovery Act Research Support: As a supplmenet to the Center for Nursing Outcomes Resarch we will purchase scientific equipment to enhance our capacity to conduct research using large data sets and to accelerate the tempo of that research. We propose to purchase a a Dell server with 2 | Health and Human Services, Department of / National Institutes of Health | 5/20/2010 |
| THE VANDERBILT UNIVERSITY | $350,550 | Grant | Trans-NIH Recovery Act Research Support: This application seeks funds to purchase a state-of-the-art small-animal fluorescence tomography system for users at Vanderbilt University. Non-invasive molecular imaging can be employed to quantitatively assess numerous physiological processes in vivo an | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| WASHINGTON UNIVERSITY, THE | $380,000 | Grant | Trans-NIH Recovery Act Research Support: While it has long been recognized that the wide array of polymorphisms in major histocompatibility complex (MHC) in combination with the direct role of MHC in activation of T cells through the T cell receptor (TCR) makes MHC the primary antigenic barrier | Health and Human Services, Department of / National Institutes of Health | 6/14/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | $405,468 | Grant | Trans-NIH Recovery Act Research Support: The Mechanism of Myosin ATPase Actin Activation Interaction of actin and myosin is the basis of muscle contraction and force generation in muscle, as well as the basis of cellular motion and intracellular traffic. In myosin II, actin binding initiates th | Health and Human Services, Department of / National Institutes of Health | 3/26/2010 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $186,534 | Grant | Trans-NIH Recovery Act Research Support: The work involves mouse embryonic stem cells and human embryonic stem cells obtained from federally-approved cell lines. The broad objective of this proposal is to enable embryonic stem cells (ESCs) to specifically recognize and bind to infarcted tissues, | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF FLORIDA | $45,150 | Grant | Trans-NIH Recovery Act Research Support: Maternal cortisol concentrations are normally increased by 2-3 fold in pregnancy. Maternal cortisol levels appear to affect fetal skeletal and visceral growth. Our previous data show reduced growth in fetuses of ewes with either increased or decreased mat | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| GOVERNMENT SCIENTIFIC SOURCE, INC. | $14,637 | Contract | : 1-BIO-PLEX II WASH STATION; BIO RAD PART # 3034377; $14,637.46 | Health and Human Services, Department of / National Institutes of Health | 1/25/2010 |
| NET ESOLUTIONS CORPORATION | $275,000 | Contract | : Provide the National Institutes of Health (NIH), Office of the Director (OD), Office of Science Policy and Analysis (OSPA) with the execution of NIH grant support implementation of the reqired NIH oversight related to the American Recovery and Reinvestmen | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| UNIVERSITY OF PITTSBURGH THE | $128,851 | Contract | : The University of Pittsburgh has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of Endometrial carcinoma (70 cases), Hepatocellular carcinoma (20 case | Health and Human Services, Department of / National Institutes of Health | 4/06/2010 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $126,562 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this proposal is to determine the mechanism(s) mediating the increased cellular damage and the impaired subsequent recovery in the diabetic brain following a stroke. The underlying hypothesis of this proposal is that the greater d | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| MOUNTAIN STATES GROUP, INC. | $327,229 | Grant | Trans-NIH Recovery Act Research Support: The Idaho Partnership for Hispanic Mental Health phase one planning project seeks to address the mental health service needs of Mexican immigrants in southwest Idaho through the development of a community-academic partnership. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This is an application for renewed CCSG funding for year 35 of the Albert Einstein Cancer Center which received its first NCI designation in 1972. There are seven established programs. These include: Immunooncology (Sc | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| IIT RESEARCH INSTITUTE | $99,757 | Grant | Trans-NIH Recovery Act Research Support: Many chronic inflammatory diseases are linked to an elevated risk of developing cancer. Yet, the functional significance of chronic inflammation in carcinogenesis is largely unknown. In the colon, strong support for a link between inflammation and cance | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| PONCE MEDICAL SCHOOL FOUNDATION INC | $140,747 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of the Ponce School of Medicine (PSM) MBRS-RISE Program is to increase the competitiveness and retention of underrepresented Hispanic students participating in biomedical research in the interdisciplinary Ph.D. Program at PSM in Puerto Ri | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| PONCE MEDICAL SCHOOL FOUNDATION INC | $344,697 | Grant | Trans-NIH Recovery Act Research Support: In the present application we are requesting funds to continue the support of the MBRS SCORE Program at the Ponce School of Medicine. The MBRS SCORE Program, since its implementation in 1985, has been the driving force in developing and strengthening the | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| PORTLAND STATE UNIVERSITY | $130,914 | Grant | Trans-NIH Recovery Act Research Support: This work aims to identify the structural interactions that underlie the process of transcription initiation. We expect to gain novel insight into the fine-scale positioning and function of TFB (Transcription Factor B) and TFE (Transcription Factor E). In | Health and Human Services, Department of / National Institutes of Health | 4/30/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $496,938 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and the specific Challenge Topic that this application addresses is: 03-DK-101 Discovery of biomarkers for disease risk, progression or response to therapy in disease | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| YESHIVA UNIVERSITY | $408,400 | Grant | Trans-NIH Recovery Act Research Support: Holz's research will attempt to provide a comprehensive assessment of the therapeutic potential of the S6K1 signaling pathway by identifying and characterizing downstream effectors of the S6K1 pathway in breast cancer cells. | Health and Human Services, Department of / National Institutes of Health | 5/30/2010 |
| WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY | $69,416 | Contract | : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula | Health and Human Services, Department of / National Institutes of Health | 3/23/2010 |
| WASHINGTON UNIVERSITY, THE | $484,350 | Grant | Trans-NIH Recovery Act Research Support: We propose to acquire an Applied Biosystems Sciex QTRAP 5500 hybrid triple quadrupole-linear ion trap mass spectrometer (MS) for LC/MS/MS analyses of biomedically important complex lipids. This program will benefit from the sensitivity and versatility of | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| DUKE UNIVERSITY | $756,423 | Contract | : The present application addresses a major area of concern in the substance use field G?? the association between attention-deficit/hyperactivity disorder (ADHD) in childhood and patterns of substance use, abuse, and dependence (as well as desistance) in l | Health and Human Services, Department of / National Institutes of Health | 4/22/2010 |
| SCRIPPS RESEARCH INSTITUTE, THE | $1,023,775 | Grant | Trans-NIH Recovery Act Research Support: Malaria causes 1-2 million deaths worldwide each year. Resistance to chloroquine, the major antimalarial drug, has emerged in all malaria subtypes and resistant strains now constitute the majority of new infections. A major cause of chloroquine resistan | Health and Human Services, Department of / National Institutes of Health | 6/21/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $499,462 | Grant | Trans-NIH Recovery Act Research Support: This is a request to replace a 2-photon confocal microscope that was purchased in 1999 with a new system incorporating several advances in multiphoton microscopy. The requested system consists of the Zeiss LSM 710 NLO confocal system and Coherent Chameleo | Health and Human Services, Department of / National Institutes of Health | 4/22/2010 |
| UNIVERSITY OF TEXAS AT ARLINGTON | $444,890 | Grant | Trans-NIH Recovery Act Research Support: Cancer is a major cause of death in United States and around the world. Numerous studies suggest that in addition to genetic factors, environmental factors, food habit and geographic location have significant contribution to the rate of cancer incidence. | Health and Human Services, Department of / National Institutes of Health | 5/10/2010 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $999,940 | Grant | Trans-NIH Recovery Act Research Support: BACKGROUND. Genetic and molecular testing technologies have expanded rapidly into the newborn screening programs that are used for nearly every U.S. newborn. These techniques lead to biomedical benefit for some infants but troubling psychosocial harms for | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $201,257 | Grant | Trans-NIH Recovery Act Research Support: This award was requested to allow the Neurobiology Department to obtain a flourescence microscope equipped with a sensitive CCD (Charge-coupled device)and a motorized stage for Array Tomography to determine with high resolution the location of multiple pr | Health and Human Services, Department of / National Institutes of Health | 4/15/2010 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $107,827 | Grant | Trans-NIH Recovery Act Research Support: The etiologies of aging, inflammation and neurodegenerative diseases, have all (with varying degrees of certitude) been associated with increased exposure to reactive oxygen species (ROS) and/or reactive nitrogen species (RNS). We have developed a cell-ba | Health and Human Services, Department of / National Institutes of Health | 5/29/2010 |
| LAB PRODUCTS INC | $57,763 | Contract | : LAB RESEARCH EQUIPMENT | Health and Human Services, Department of / National Institutes of Health | 4/07/2010 |
| MICHIGAN TECHNOLOGICAL UNIVERSITY | $388,708 | Grant | Trans-NIH Recovery Act Research Support: The goal of this study is to develop new technology to reduce secondary injury following spinal cord injury. Currently, there are no viable treatments for patients who have sustained spinal cord injury. Clinically, interventions involve injection of agent | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| THE VANDERBILT UNIVERSITY | $232,500 | Grant | Trans-NIH Recovery Act Research Support: ???cell proliferation is high during perinatal stages, but declines precipitously prior to adulthood, due in part to increased expression of cell cycle inhibitors with age. Insulin resistant states, such as pregnancy and obesity, stimulate replication in | Health and Human Services, Department of / National Institutes of Health | 6/07/2010 |
| ONTARIO INSTITUTE FOR CANCER RESEARCH | $637,000 | Contract | : Ontario has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of endometrial, papillary, cervical, lung, stomach, colon, and rectal cancer specimens (392 | Health and Human Services, Department of / National Institutes of Health | 6/25/2010 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $869,840 | Grant | Trans-NIH Recovery Act Research Support: This application requests funds for purchase of a two-photon microscopy system with imaging and uncaging capabilities that will constitute a shared facility in the Departments of Neurosciences and Radiology at the University of California, San Diego. Two- | Health and Human Services, Department of / National Institutes of Health | 5/27/2010 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $407,000 | Grant | Trans-NIH Recovery Act Research Support: Major depression and alcoholism feature lower-than-normal densities of neurons and glial cells in the prefrontal cortex (PFC) brain region heavily involved in addictive and affective disorders. In establishing the pathophysilology of MDD and alcoholism, | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $698,491 | Grant | Trans-NIH Recovery Act Research Support: A Core Center Grant is proposed to support vision research at The University of Texas Southwestern Medical Center. The recent expansion of vision research on our campus has created an opportunity to enhance visual science research at U.T. Southwestern Med | Health and Human Services, Department of / National Institutes of Health | 6/10/2010 |
| UNIVERSITY OF UTAH, THE | $32,358 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal focuses on the assembly of metal centers cytochrome c oxidase (CcO) using yeast as an experimental system. CcO deficiency is an important cause of respiratory chain disorders in infants that can present a | Health and Human Services, Department of / National Institutes of Health | 5/21/2010 |
| BAYLOR COLLEGE OF MEDICINE | $127,421 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to improve our ability to target drugs to particuliar protein conformations and thereby deliver highly specific drug action. Conformation changes and protein interactions underlie the function of many protiens, but are partic | Health and Human Services, Department of / National Institutes of Health | 4/22/2010 |
| UNIVERSITY OF CONNECTICUT | $792,159 | Grant | Trans-NIH Recovery Act Research Support: This project will design novel regenerative therapy approaches using osteoclasts as cellular vectors to deliver signals to the bone marrow microenvironment. Using these methods we propose to modulate properties of the bone marrow compartment to increase i | Health and Human Services, Department of / National Institutes of Health | 4/21/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: ESCRIPTION (provided by applicant): Khodakhah, Kamran To understand brain function in health and disease one needs to elucidate how it processes sensory inputs, how it encodes information, and how it computes. Exploration of these facets requires tools wh | Health and Human Services, Department of / National Institutes of Health | 5/13/2010 |
| BECTON, DICKINSON AND COMPANY | $125,562 | Contract | : Purchase of: FACSCalibur Flow Cytometer | Health and Human Services, Department of / National Institutes of Health | 6/10/2010 |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON | $179,968 | Grant | Trans-NIH Recovery Act Research Support: These studies are designed to extend the work in the parent grant on the role of the cytokine TSLP in regulating B cell development and function. Specifically, we will examine changes in the B cell transcriptome following exposure to TSLP, looking both g | Health and Human Services, Department of / National Institutes of Health | 6/29/2010 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $102,060 | Grant | Trans-NIH Recovery Act Research Support: The adipoeyte-secreted hormone leptin signals the amount of energy stored in adipose tissue to the central nervous system. We have shown, in the context of this grant, that leptin administration to normalize the relative leptin deficiency induced by short | Health and Human Services, Department of / National Institutes of Health | 4/05/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $498,683 | Grant | Trans-NIH Recovery Act Research Support: This project focuses on the production to MRM assays for the quantification of one or more protein in clinical sample sets. A group of very experienced investigators with targeted studies to address key clinical questions will use the dual liquid chromato | Health and Human Services, Department of / National Institutes of Health | 4/08/2010 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $297,846 | Grant | Trans-NIH Recovery Act Research Support: This project addresses the efficient operation of the Teen-LABS Data Coordinating Center (DCC) which is essential. In the spring of 2009, at the request of the NIDDK, Dr. Steven Belle and colleagues from The Epidemiology Data Center at the University Of P | Health and Human Services, Department of / National Institutes of Health | 6/14/2010 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Multiphoton microscopy is a powerful new tool that facilitates the study of discrete cellular processes within the three-dimensional, natural environment of intact organs in living animals. During the past few years, multi-photon microscopy has revolution | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $1,234,261 | Grant | Trans-NIH Recovery Act Research Support: A major goal of biologists is to G?seeG? inside cells to discover where and when each individual protein acts. Conventional light microscopy approaches limit our spatial resolution to ~250 nm, which in several instances is only slightly smaller than the o | Health and Human Services, Department of / National Institutes of Health | 5/13/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $121,619 | Grant | Trans-NIH Recovery Act Research Support: This proposal ?A Novel Ligand for PBR Imaging? is to investigate neuroinflammation in HIV dementia using a novel translocator protein (TSPO) ligand known as [11C]DPA-713. Currently, the ligand used most commonly for evaluating PBR binding is [11C]-R-PK111 | Health and Human Services, Department of / National Institutes of Health | 3/19/2010 |
| RFCUNY - THE GRADUATE CENTER | $471,925 | Grant | Trans-NIH Recovery Act Research Support: With changing family structure and employment opportunities in the United States, young children are highly likely to experience residential mobility and neighborhood change. However, the effects of residential instability on young children are not well u | Health and Human Services, Department of / National Institutes of Health | 4/14/2010 |
| AEROSOL DYNAMICS INC. | $2,691,763 | Grant | Trans-NIH Recovery Act Research Support: This is a research project to develop a new 'smart sampler' to provide cost-effective, time-resolved monitoring of chemical constituents of ambient particles, with application to characterization for environmental health studies. The project uses scientis | Health and Human Services, Department of / National Institutes of Health | 6/05/2010 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $507,998 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this proposal is to establish the infrastructure for the development of the World Wide Web representation for the Digestive Diseases Research Core Centers (DDRCCs) and the Digestive Diseases Research Development Centers (DDRDCs). This | Health and Human Services, Department of / National Institutes of Health | 6/14/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The Human Immune Monitoring Center (HIMC) aims to acquire and co-develop one of the world's first mass spectrometry-based systems for single-cell analysis using unique mass tags; this system is known as Cytometry via Time of Flight or CyTOF. With this tec | Health and Human Services, Department of / National Institutes of Health | 5/20/2010 |
| BECTON, DICKINSON AND COMPANY | $48,750 | Contract | : Purchase of: LSR II Upgrades | Health and Human Services, Department of / National Institutes of Health | 5/20/2010 |
| JOHNS HOPKINS UNIVERSITY, THE | $498,474 | Grant | Trans-NIH Recovery Act Research Support: This award will be used to obtain a new multiphoton microscope to study the physiology and pathophysiology of intestinal tissue, a pancreas and a heart using whole animal models. The instument will be used mainly by four NIH funded investigators, the memb | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| THE INSTITUTE FOR CANCER RESEARCH | $10,665 | Grant | Trans-NIH Recovery Act Research Support: Title: Role of RPL22 in Thymocyte Development Abstract: We are asking for supplemental funds to accelerate the pace of discovery in our project seeking to understand the basis for the ?? T lineage-specific requirement for the ribosomal protein, Rpl22. Ri | Health and Human Services, Department of / National Institutes of Health | 5/24/2010 |
| CEDARS-SINAI MEDICAL CENTER | $17,967 | Contract | : The Cedars-Sinai Medical Center has been awarded a contract to provide tumor types to the NCI for The Cancer Genome Atlas (TCGA) project. Specifically this award is to fund the provision of cervical cases. These cases are all primary and untreated. The | Health and Human Services, Department of / National Institutes of Health | 6/23/2010 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $8,658 | Grant | Trans-NIH Recovery Act Research Support: Although it has been known for about 100 years that diptheria (DPH) toxin targets the transaltion elongation factor 2, the mechanism by which the inhibition of cell growth and resulting death occurs is not well understood. This ARRA supplement is to all | Health and Human Services, Department of / National Institutes of Health | 6/01/2010 |
| METHODIST HOSPITAL RESEARCH INSTITUTE, THE | $488,566 | Grant | Trans-NIH Recovery Act Research Support: Obesity is a major health problem in the United States. It increases the risk of insulin resistance (IR) and metabolic syndrome (MS), a cluster of cardiovascular disease (CVD) risk factors, and leads to additional pathologies, including non-alcoholic stea | Health and Human Services, Department of / National Institutes of Health | 6/01/2010 |
| JBS INTERNATIONAL, INC. | $2,647,435 | Contract | : The purpose of this project was to create the Go4Life exercise campaign including to create a communication plan and public health messages, develop outreach strategies and begin to identify community partners to raise awareness of the importance of physi | Health and Human Services, Department of / National Institutes of Health | 5/03/2010 |
| UNIVERSITY OF UTAH, THE | $122,000 | Grant | Trans-NIH Recovery Act Research Support: We request funding from the Shared Instrumentation Grant Program (S10) to purchase a Covaris E210 Adaptive Focused Acoustic (AFA) instrument for the extraction of cellular RNA and the preparation of DNA for sequencing. The E210 would relieve the current b | Health and Human Services, Department of / National Institutes of Health | 4/15/2010 |
| CHESTNUT HEALTH SYSTEMS, INC. | $369,875 | Grant | Trans-NIH Recovery Act Research Support: Comprehensive and standardized biopsychosocial assessments are a key piece of infrastructure in the drive towards evidence-based and effective substance abuse treatment. Demands to cover more areas and constructs mean that such assessments can take 1-2 ho | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| MINUS K TECHNOLOGY INC | $8,250 | Contract | : 3 vibration isolation units purchased from the manufacturer | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PRECISION GENOME ENGINEERING | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Genome engineering is an emerging field in which site specific rare cutting endonucleases are used to create DNA double strand breaks at desired genomic sites. Endonuclease-induced double strand breaks are resolved by endogenous DNA repair pathways, resul | Health and Human Services, Department of / National Institutes of Health | 4/05/2010 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $179,800 | Grant | Trans-NIH Recovery Act Research Support: Microscale systems have a strong and increasing presence in basic and applied biomedical research. The ability to manipulate and define an experimental system at the scale of micrometers has revealed much about how cells interact with their complex enviro | Health and Human Services, Department of / National Institutes of Health | 4/15/2010 |
| YALE UNIVERSITY | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of numerous cysts in affected kidneys that lead to renalfailure in about half of ADPKD patients. The disease burden from ADPKD in U.S. alone is estimated at 6 | Health and Human Services, Department of / National Institutes of Health | 4/01/2010 |
| VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO | $439,920 | Grant | Trans-NIH Recovery Act Research Support: This award is to help support the replacement of an existing older cell sorter instrument within a core facility with a new upgraded model, a MoFlo XDP High Speed Cell Sorter manufactured by Beckman Coulter. The requested new instrument represents much im | Health and Human Services, Department of / National Institutes of Health | 5/20/2010 |
| MOUNT SINAI SCHOOL OF MEDICINE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: A multiphoton laser scanning microscope is requested for the use of eight major users at the Mount Sinai School of Medicine. The instrument will be used for multichannel fluorescence and second harmonic generation imaging of a variety of organs and tissue | Health and Human Services, Department of / National Institutes of Health | 5/27/2010 |
| UNIVERSITY OF NEW MEXICO | $9,586,673 | Grant | Trans-NIH Recovery Act Research Support: The Core Facility to be renovated, the University of New Mexico Center for Molecular Discovery, represents a one of a kind sustainable facility (technologically, financially, architecturally) that will have local, regional, national and international impa | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $125,800 | Grant | Trans-NIH Recovery Act Research Support: During fasting, elevations in circulating pancreatic glucagon promote hepatic glucose output through induction of the gluconeogenic program by the CREB coactivator TORC2. Sequestered in the cytoplasm during feeding, TORC2 translocates to the nucleus in re | Health and Human Services, Department of / National Institutes of Health | 4/09/2010 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $111,875 | Grant | Trans-NIH Recovery Act Research Support: There are two main goals of our proposal. The first goal is to acquire long-term clinical and genetic information of the most common genetic deletion known (DiGeorge syndrome type 1; DGS1), affecting 1 in 4,000 live births. This information will allow u | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $154,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) is a major cause of morbidity and mortality in the USA and worldwide. While disease prevalence varies with age, sex, and population, it is estimated that in 2005, 20.6 million Americans aged e20 y | Health and Human Services, Department of / National Institutes of Health | 4/07/2010 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $650,167 | Grant | Trans-NIH Recovery Act Research Support: Meiosis is a specialized cell division process, common to sexually reproducing eukaryotes, that reduces diploid zygotes to recombinant haploid gametes. Defects in meiosis have profound consequences for human health. More than half of human miscarriages re | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $486,094 | Grant | Trans-NIH Recovery Act Research Support: This supplement is designed to allow us to mine our recently published database of spatial and temporal gene expression in lymphoid and stomal cells in the thymus. Our goal is to identify new stomal-to-lymphnoid signals that regulate stage-specific devel | Health and Human Services, Department of / National Institutes of Health | 6/14/2010 |
| BAYLOR COLLEGE OF MEDICINE | $303,492 | Grant | Trans-NIH Recovery Act Research Support: This proposal is requesting funds to purchase a Thermo Electron Delta V Advantage Isotope Ratio Mass Spectrometer with a H/Device, a GasBench II, and the accompanied accessories. The Delta V mass spectrometer system will provide accurate and automated sta | Health and Human Services, Department of / National Institutes of Health | 4/08/2010 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $496,686 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to shorten the timeline for activating National Cancer Institute(NCI) sponsored Cooperative Group phase 1-3 clinical trials thereby allowing patient accrual to the trials to start sooner and results analyzed and reported faster. T | Health and Human Services, Department of / National Institutes of Health | 5/19/2010 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $137,250 | Grant | Trans-NIH Recovery Act Research Support: Dr. Rothenberg has indicated that each 2nd endoscopy (in week 12) will cost $3,000.00. This cost includes pre-op preparation, anesthesia, equipment, biopsy procurement, and pathology specimen preparation and analysis. | Health and Human Services, Department of / National Institutes of Health | 6/28/2010 |
| WASHINGTON METROPOLITAN AREA TRANSIT AUTHORITY | $69,828 | Contract | : These ARRA funds provided SmartBenefits on SmarTrip cards to NIH employees that they may use to ride MetroBus or MetroRail. The fare media may also be used on DASH, Ride On, Fairfax Connector, ART, CUE, Loudoun County Transit, Omniride, TheBus, DC Circula | Health and Human Services, Department of / National Institutes of Health | 4/07/2010 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $59,634 | Grant | Trans-NIH Recovery Act Research Support: This application is the response of three existing Summer Research Programs for Science Teachers at Columbia University, Stanford University, the University of Texas Southwestern Medical Center, and the nascent Summer Research Program at National Jewish M | Health and Human Services, Department of / National Institutes of Health | 6/01/2010 |
| NEW YORK UNIVERSITY (INC) | $590,479 | Grant | Trans-NIH Recovery Act Research Support: As antibiotics are becoming less and less effective against bacteria such as the notorious MRSA, there is a great need for new anti-infective strategies that do not involve conventional antibiotics. We propose to develop and implement two such strategies, | Health and Human Services, Department of / National Institutes of Health | 6/28/2010 |
| THE VANDERBILT UNIVERSITY | $628,478 | Grant | Trans-NIH Recovery Act Research Support: This program describes a chemical synthesis route to biologically active natural products. Mitomycin C is a clinically-used small molecule for chemotherapy that functions as a DNA cross-linking agent. No other known chemotherapeutic duplicates this mechan | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $64,498 | Grant | Trans-NIH Recovery Act Research Support: The award of the ARRA administrative supplement has allowed us to complement and strengthen the Columbia DERC's existing activities in diabetes research, with the ultimate goals of accelerating the pace of discovery and facilitating the achievement of res | Health and Human Services, Department of / National Institutes of Health | 4/30/2010 |
| UNIVERSITY OF WASHINGTON | $137,980 | Grant | Trans-NIH Recovery Act Research Support: Our research is aimed at determining how cysteinates influence function in non-heme iron enzymes. Cysteinate-ligated non-heme iron containing SOR and NHase are involved in the detoxification of superoxide radicals, and nitrile wastes, respectively. Supero | Health and Human Services, Department of / National Institutes of Health | 3/16/2010 |
| UNIVERSITY OF TEXAS AT AUSTIN | $99,534 | Grant | Trans-NIH Recovery Act Research Support: Cancer is one of the leading causes of death in the US. Chemotherapy remains an important cancer treatment modality. Traditionally, cytotoxic molecules that activate only a single tumorkilling mechanism are used. Combination chemotherapy is now a common p | Health and Human Services, Department of / National Institutes of Health | 6/28/2010 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $361,760 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of this proposal is to develop and deploy cutting edge technologies and chemical genomic tools and to understand the effects of small molecule inhibitors in vivo, and to characterize the model organism Saccharomyces cerevisiae on a s | Health and Human Services, Department of / National Institutes of Health | 5/06/2010 |
| LOCKHEED MARTIN ACULIGHT CORPORATION | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Urologic disease represents a debilitating medical problem that adversely affects the lives of people of all ages and backgrounds. Surgical lasers form the standard of care for many treatments and endoscopic procedures in the prostate, kidney, ureter, bl | Health and Human Services, Department of / National Institutes of Health | 5/24/2010 |
| BAYLOR COLLEGE OF MEDICINE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Statement of Purpose (15 words): This instrument will help transform the way scientists from a broad range of disciplines conduct research to understand the molecular mechanisms of human diseases, including disease gene cloning, cancer, gene expression, s | Health and Human Services, Department of / National Institutes of Health | 6/10/2010 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $3,853,630 | Grant | Trans-NIH Recovery Act Research Support: Pacific-Southwest Regional Center of Excellence for Biodefense and Emerging Diseases (the Center) is a research consortium comprising 28 projects clustered within six programs. The Center also features five core facilities that serve the entire region. Al | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF KENTUCKY | $31,928 | Grant | Trans-NIH Recovery Act Research Support: Circadian rhythms have long been known to influence behavioral and biological processes such as physical activity and feeding behavior. The fundamental importance of this system, which works to link physiology with the day/night cycle, is underscored by i | Health and Human Services, Department of / National Institutes of Health | 5/19/2010 |
| UNIVERSITY OF WASHINGTON | $100,000 | Grant | Trans-NIH Recovery Act Research Support: As a part of experiments proposed in the original proposal, we have recently discovered that the lipid-nanoparticle platform not only is an effective anti-HIV drug carrier, but also provides outstanding MR image enhancement and improved disposition proper | Health and Human Services, Department of / National Institutes of Health | 6/07/2010 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $201,428 | Grant | Trans-NIH Recovery Act Research Support: We seek support from the Recovery Act Funds to expand the scope of the specific aims, research design, and methods of GM065997, which bears the title: Regulation of cullin-RING ligases by Nedd8. Nedd8 is a ubiquitin-like protein that is reversibly conjuga | Health and Human Services, Department of / National Institutes of Health | 6/25/2010 |
| UNIVERSITY OF SOUTH FLORIDA | $72,728 | Grant | Trans-NIH Recovery Act Research Support: The study of viral dynamics is one of the most important developments in recent HIV/AIDS research for understanding HIV pathogenesis and antiretroviral (ARV) therapies. However, most studies focused on short-term viral dynamics, and the models therein may | Health and Human Services, Department of / National Institutes of Health | 4/08/2010 |
| UNIVERSITY OF LOUISVILLE | $616,281 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this proposal is to determine how tiny microvesicles (so called exosomes) released from lung tumor cells promote an inflammator response, and growth of lung tumors. Our results showed that pretreatment of A/J mice with tiny microvesicl | Health and Human Services, Department of / National Institutes of Health | 4/12/2010 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $410,460 | Grant | Trans-NIH Recovery Act Research Support: The mission of the Southwest Oncology Group is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The Group's network includes more than 5,000 physicians who practice at nearly 550 in | Health and Human Services, Department of / National Institutes of Health | 6/11/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $347,628 | Grant | Trans-NIH Recovery Act Research Support: Prospective Studies of the Pathogenesis of Schizophrenia - ARRA We will study neuronal oscillations and EEG synchrony in high risk and control 1 and 2 year olds. We will test one main hypothesis - children at genetic high risk will have reduced resting | Health and Human Services, Department of / National Institutes of Health | 5/22/2010 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $95,718 | Grant | Trans-NIH Recovery Act Research Support: The evolution of enzymes was a critical element of the emergence of life on Earth and its subsequent divergence to occupy a vast range of ecological niches. Most enzymes have impressive catalytic capabilities that have been honed over 3.8 billion years of | Health and Human Services, Department of / National Institutes of Health | 5/07/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $99,600 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): It is estimated that, on average, 50% of the 10 million men with diabetes mellitus (DM) have erectile dysfunction (ED) with both Type 1 and Type 2 DM nearly equally associated with ED. Although efficacious orally acti | Health and Human Services, Department of / National Institutes of Health | 4/27/2010 |
| PUGET SOUND BLOOD CENTER PROGRAM | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement award is to support the research of the parent K01 entiltled: MASTL Kinase activity in megakaryocytpoeisis. We are particularly interested in extensively characterizing the gene trap mice deficient in MASTL kinase. These m | Health and Human Services, Department of / National Institutes of Health | 5/27/2010 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $226,732 | Grant | Trans-NIH Recovery Act Research Support: Social network analysis (SNA) is one tool for advancing the development of evaluation metrics to assess the key objectives of Clinical and Translational Science Awards (CTSA). SNA is particularly suitable for describing relationships with the most promisi | Health and Human Services, Department of / National Institutes of Health | 4/15/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $226,604 | Grant | Trans-NIH Recovery Act Research Support: The goal fo this proposed research is to begin to understand how a macrophage responds to Samonella infection and how Salmonella virulence factors alter tht response. We will infect cells with the parent 14028 and isogenic derivatives either missing spec | Health and Human Services, Department of / National Institutes of Health | 6/14/2010 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $91,024 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement entitled !The Cullin-ROC Family of E3 Ubiquitin Ligases! for GM067113, an investigation aimed at a long-term goal of determining the function and mechanism of the cullin-RING family of E3 ubiquitin ligases (CRLs), the | Health and Human Services, Department of / National Institutes of Health | 6/25/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $632,000 | Grant | Trans-NIH Recovery Act Research Support: The Einstein DRTC serves as a nexus to i) enhance diabetes research, education and training; ii) to attract, mentor and retain research investigators; iii) provide state-of-the-art Core services to maximize research productivity; iv) foster interdiscipli | Health and Human Services, Department of / National Institutes of Health | 5/11/2010 |