Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $46,952 | Grant | Trans-NIH Recovery Act Research Support: Proper functioning of the immune system requires elaborate network of negative regulatory mechanisms to modulate the strength of activation signal or to disengage the immune response after successful completion of a defense mounted against pathogens. One | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF WASHINGTON | $99,995 | Grant | Trans-NIH Recovery Act Research Support: Our research studies proposed in parental grant recently funded by NIAID (1R21AI079778-01) focused on establishing cellular and animal models of myelokathexis (MK or WHIM syndrome), a stem cell disorder of immunodeficiency caused by heterozygous mutations | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $47,680 | Grant | Trans-NIH Recovery Act Research Support: This suplement involves the recruitment of a middle school science teacher to perform food allergy reseach in the laboratory during the summer months. Food allergy is a significant public health problem. The cause for the disease is poorly understood and | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| EMORY UNIVERSITY | $509,947 | Grant | Trans-NIH Recovery Act Research Support: Title: Melatonin and Nighttime Blood Pressure in African Americans. Our ARRA-funded project is a randomized, double-blind, placebo-controlled, crossover clinical trial that is testing the effect of 24 mg/night of melatonin supplementation on nighttime bl | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF SOUTHERN MISSISSIPPI | $120,684 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent proposal is to develop an efficient cancer cell-specific siRNA delivery system by folate receptor (FR)-assisted endocytosis. However, unmodified and unprotected siRNA in the parent proposal is susceptible to hydrolytic degradation b | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $105,987 | Grant | Trans-NIH Recovery Act Research Support: The prevention of any malignancy inevitably depends on the successful interruption of the transition from a precursor to a malignant state. To accomplish this, the precursor must be known. The precursor to pelvic serous carcinoma has not been previously i | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $70,267 | Grant | Trans-NIH Recovery Act Research Support: Early detection of prostatic adenocarcinoma (CAP) offers the best hope of curing it. Currently, the only way to definitively diagnose CAP is through histological analysis of excised tissue, obtained via blind sextant trans-rectal ultrasound (TRUS)-directe | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF FLORIDA | $146,497 | Grant | Trans-NIH Recovery Act Research Support: Muscle wasting is a prevalent health care problem that has a high morbidity in the adult population and causes a loss of muscle strength, increased vulnerability to falls, increased health care utilization and a reduced quality of life. In order to develo | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SPAULDING REHABILITATION HOSPITAL (SRH) VOLUNTEER SERVICES, | $136,902 | Grant | Trans-NIH Recovery Act Research Support: Excessive bone loss occurs following spinal cord injury (SCI) leading to osteoporosis and an increased risk of fracture. While the underlying cause of this bone loss remains to be clarified, it is distinct in severity and pattern from other known causes o | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $16,038 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of the parent grant is to obtain the 3D crystal structure of eukaryotic facilitated glucose transporters. The GLUT1 from human red blood cells (RBCs) is an important human facilitated glucose transporter. Glut1 catalyzes the equilibratio | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $200,000 | Grant | Trans-NIH Recovery Act Research Support: To facilitate the structural determination of this important glucose transporter, the specific aims of this request are to characterize GLUT1 samples isolated directly from human RBCs as well as the development of an heterologous-expression system. Clear | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $135,378 | Grant | Trans-NIH Recovery Act Research Support: These studies will be the first to systematically investigate alternative splicing in human heart failure, and among the first to examine regulation of splicing on a genome-wide level in human disease. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $107,195 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Poor ischemic tolerance and loss of ischemic preconditioning are hallmarks of the aged heart, and contribute to the fact that age is the strongest risk factor for cardiovascular disease. However, the metabolic adjustme | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WASHINGTON UNIVERSITY, THE | $168,015 | Grant | Trans-NIH Recovery Act Research Support: This project will empirically test whether quantitative information about drug dose effects on brain function can be extracted from functional Magnetic Resonance Imaging (fMRI) We have developed a method for determining the ED50 - the drug dose required t | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OKLAHOMA STATE UNIVERSITY | $10,986 | Grant | Trans-NIH Recovery Act Research Support: The current study is an intervention designed to help reduce parents' distress associated with their child's recent diagnosis of cancer. The intervention will include the expertise of both psychologists and nurses in teaching parents skills to help manage | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF WASHINGTON | $126,782 | Grant | Trans-NIH Recovery Act Research Support: New non-destructive tissue imaging tools, including optical projection tomography (OPT) and micro-computed tomography (microCT) are now being utilized for model organism research. These technologies will have appeal to developmental biologists and others | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $345,846 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement was requested to speed research progress on the specific aims of the R24 grant National Center for Medical Rehabilitation Research: Integrated Molecular Core. The overall goal of the parent grant is to provide services and tra | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| EMORY UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Establishment of atransgenic monkey model of Huntington's disease This study is propose to monitor the gene expression and miRNA expression profile of the peripheral blood of these HD monkeys at six months intervals throughout the two budgeted years. Whi | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NEW MEXICO STATE UNIVERSITY | $339,833 | Grant | Trans-NIH Recovery Act Research Support: The MORE Division of NIGMS has supported an R25 G?BridgeG? grant at NMSU, Las Cruces since October 1, 1992. This project is a Bridges to the Future: Associate to the Baccalaureate Program. The specific program at NMSU is entitled: Bridges to the Bacca | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $100,506 | Grant | Trans-NIH Recovery Act Research Support: According to the 2005 Woodrow Wilson Foundation report, Diversity & the Ph.D., while African Americans and Hispanics together currently constitute approximately 1/3 of the U.S. citizens in the Ph.D. candidate age range, they only receive 7% of the doctora | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $140,931 | Grant | Trans-NIH Recovery Act Research Support: The Medical Sciences Campus of the University of Puerto Rico (UPR?MSC) has had a long history of NIH? NIGMS supported MBRS Programs as evidenced by 22 years of uninterrupted funding. The MBRS RISE Program at the UPR MSC, currently in its ninth year of sup | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF GUAM | $79,200 | Grant | Trans-NIH Recovery Act Research Support: BUILDING TOWARD 2010 AT THE UNIVERSITY OF GUAM | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF MARYLAND | $164,637 | Grant | Trans-NIH Recovery Act Research Support: Development of two new courses - population genetics and modern approaches to the epidemiology and control of infestious diseases for inclusion in the MBRS RISE curriculum. This in turn brought to five, the number of new courses introduced into the BS De | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RFCUNY- QUEENSBOROUGH COMMUNITY COLLEGE | $190,894 | Grant | Trans-NIH Recovery Act Research Support: This proposal is an application for an administrative supplement to the existing Bridges to the Baccalaureate Program (GM065096-07) at Queensborough Community College (QCC). The goals and objectives of the Bridges partnership between QCC and Queens Colleg | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF TEXAS AT BROWNSVILLE | $164,171 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funding for the MBRS RISE Program at the University of Texas at Brownsville supports student development activities that address MBRS RISE student needs in critical thinking, reading, communication and mathematics skills to enhance preparation to | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION | $48,237 | Grant | Trans-NIH Recovery Act Research Support: A central goal of our current North San Diego Bridges to the Future program is to enhance the academic achievement of underrepresented science majors. Our grant accomplishes this by providing Supplemental Instruction (SI) for courses in mathematics and | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | $230,738 | Grant | Trans-NIH Recovery Act Research Support: We will develop a suite of programs aimed at improving K-12 and the general public's understanding of health science advances created by National Institutes of Health funded clinical and basic research in the areas of stem cell biology and regenerative m | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| TEACHERS COLLEGE, COLUMBIA UNIVERSITY | $101,565 | Grant | Trans-NIH Recovery Act Research Support: Increased rates of obesity in children and adolescents accompanied by increases in type 2 diabetes and cardiovascular disease risk factors have lead to the need for wide-spread and in-depth education for youth to understand basic health science research o | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $149,894 | Grant | Trans-NIH Recovery Act Research Support: Under SEPA funding, we created a very effective school year experience for about 3,000 Birmingham area middle school students each year. Our programs are reaching underserved populations because most (98%) of the students in the Birmingham City School sy | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $226,568 | Grant | Trans-NIH Recovery Act Research Support: Through funding from the National Institutes of Health, National Center for Research Resources Science Education Partnership Award, the Health Sciences and Technology Academy (HSTA) has built a partnership with investigators within the Clinical translatio | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF ROCHESTER | $183,795 | Grant | Trans-NIH Recovery Act Research Support: This supplement grant will support broader dissemination and adoption of our SEPA-funded curriculum modules. It will also provide opportunities for increasing the involvement of scientists in bringing information on biomedical science and research to hig | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $119,136 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to provide a novel representation of the flexibility of biological macromolecules that is computationally tractable and usable in simulations such as automated docking. The approach is based on the development of a hier | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| GEORGETOWN UNIVERSITY (THE) | $150,484 | Grant | Trans-NIH Recovery Act Research Support: Interventions to Test the alpha 7 Nicotinic Receptor Model in Schizophrenia- The aim of the supplement is to add an eye-movement measure to our ongoing clinical trial of a novel nicotinic agonist strategy in schizophrenia patients with negative symptoms. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $110,081 | Grant | Trans-NIH Recovery Act Research Support: Head trauma affects 1.5 million people annually in the US, leading to debilitating neurological disorders, including epilepsy. After traumatic brain injury, 5% of the patients develop post-traumatic epilepsy, and following penetrating head injuries this n | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| WAKE FOREST UNIVERSITY | $69,901 | Grant | Trans-NIH Recovery Act Research Support: Exercise intolerance due to diastolic heart failure (DHF) is a major cause of disability among older Americans. However, relatively little is known regarding the pathophysiology and potential treatment of this pivotal outcome. Several lines of evidence su | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $499,099 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to understand how mutations in voltage-gated ion channels cause episodic weakness and stiffness in several heritable forms of periodic paralysis and myotonia. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $661,549 | Grant | Trans-NIH Recovery Act Research Support: Despite substantial progress in the past two decades, cancer remains the leading cause of death by disease in US children between 1 and 15 years of age. Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and cure rates are approaching | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $99,839 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement request in support of NCI award R37-CA44848-23. This application requests funds for the purchase of a new large-scale autoclave to replace an old unit that is barely functional. The new unit will allow the large-sca | Health and Human Services, Department of / National Institutes of Health | 7/08/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $97,853 | Grant | Trans-NIH Recovery Act Research Support: Esophageal Cytoprotection: Agents and Mechanisms (ARRA) The long term goal of this proposal is to understand the pathogenesis of gastroesophageal reflux disease (GERD), and by this means, to open up new avenues for its diagnosis and treatment. The goal is | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $83,315 | Grant | Trans-NIH Recovery Act Research Support: The overall aim of this research is to understand how regulatory neurotransmitters and gastrointestinal hormones act through changes in intracellular free Ca2+ to bring about digestive enzyme secretion by pancreatic acinar cells. This proposal focuses on | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $78,440 | Grant | Trans-NIH Recovery Act Research Support: Drugs have varying capacities to penetrate the genital tract compartments based on their physicochemical properties and affinities for drug transport proteins. Using drug therapy with intrinsically enhanced penetrations into the genital tract would be opt | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $82,243 | Grant | Trans-NIH Recovery Act Research Support: Bacteriorhodopsin and halorhodopsin are the simplest ion pumps, and prototypes of the ubiquitous seven-transmembrane-helical proteins. We have made unusual progress in the past years and now propose to test and extend the resulting detailed step-by-step h | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $178,891 | Grant | Trans-NIH Recovery Act Research Support: STAT3 Functional Defects and a Novel Therapeutic Approach for Hyper IgE Syndrome -- Autosomal Dominant Hyper IgE Syndrome (AD-HIES) is caused by heterozygous hypomorphic mutations of the transcription regulator STAT3. Characteristically, these mutations o | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WASHINGTON | $216,758 | Grant | Trans-NIH Recovery Act Research Support: This supplement supports an R01 to investigate the neural mechanisms controlling voluntary hand and arm movement in primates. In particular, the supplement is needed to pursue Aims 3-5 of the original proposal. To obtain information important for the u | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $130,787 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement Request is for work within the scope of the Parent Grant, which aims to establish the cellular and synaptic mechanisms by which a defined central pattern generator (CPG) circuit is configured by integrated descending, hormon | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $164,000 | Grant | Trans-NIH Recovery Act Research Support: Our Administrative ARRA Supplement Aims remain: (1) Investigate novel, Rho GTPase-mediated, signaling events involving transmembrane semaphorin reverse signaling during Drosophila neural development, and; (2) Utilize genetically encoded fluorescent intrac | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LOCKHEED MARTIN ACULIGHT CORPORATION | $230,457 | Grant | Trans-NIH Recovery Act Research Support: In Phase 1, we successfully developed a research cochlear infrared stimulator and identified the optimal parameter set for this highly selective stimulation technique in the gerbil cochlea. Based on these promising results, the purpose of our original Ph | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MARYLAND | $340,001 | Grant | Trans-NIH Recovery Act Research Support: Antibodies directed at various targets (especially Gal al,3Gal) and complement are pivotal mediators of hyperacute rejection of the heart, lung, and other organs. However in pig-to-human and pig-to-non-human primate models, we have consistently found that | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $1,413,300 | Grant | Trans-NIH Recovery Act Research Support: The Johns Hopkins University AIDS Clinical Trials Unit (CTU) will bring together three independently funded HIV clinical research groups that perform (1) adult and (2) pediatric treatment trials, and (3) HIV prevention research. These three groups will fo | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE VANDERBILT UNIVERSITY | $293,588 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will support the creation and deployment of computer software that will enable each of the seven sites in IeDEA Region 2 (Caribbean, Central and South America) to transmit HIV epidemiology research data that is quality contr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $48,121 | Grant | Trans-NIH Recovery Act Research Support: The 2 summer students that were employed under ARRA subcontract, Pial Hossain and Doug Jacobs, were both pre-med students at UCSD and Brown University, respectively. Each of them was assigned to a particular subtopic of our ongoing grant that aims at unde | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $98,607 | Grant | Trans-NIH Recovery Act Research Support: This award funds the purchase of two instruments as an administrative supplement to the grant U01 AI75490-01 G?Integrated Dual-Use Systems for Bio-Defense & Sepsis DiagnosisG?. The aim of the parent grant is to develop a user-friendly assay system aimed | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $798,964 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this U01 application from the Dana-Farber/Harvard Cancer Center (DF/HCC) is to provide clinical and scientific experience and patient resources to perform Phase I single agent clinical trials* Phase I agent combination clinical tr | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $717,824 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): The goals of our Phase 1 research program at MSKCC | Health and Human Services, Department of / National Institutes of Health | 7/28/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $247,675 | Grant | Trans-NIH Recovery Act Research Support: This proposal responds to RFA-CA-07-505 'The American College of Radiology Imaging Network' and addresses the needs of ACRIN's Biostatistics and Data Management Center (BDMC). This proposal is submitted in coordination with a proposal from the Headquarter | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| INTER TRIBAL COUNCIL OF ARIZONA, INC. | $251,361 | Grant | Trans-NIH Recovery Act Research Support: To eliminate cancer health disparities among American Indians by closing the gap between the health needs of the community and the promise of cancer prevention and cure made possible by a repsonive health delivery and research system. | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| MAYO CLINIC | $616,035 | Grant | Trans-NIH Recovery Act Research Support: Chronic lymphocytic leukemia (CLL) is a malignant B cell lymphoproliferative disorder and is most common in Caucasians, with a lifetime risk of 1 in 200. It has been known for decades that a genetic component affects CLL risk, with the risk of CLL on the | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MAYACHITRA INC | $216,371 | Grant | Trans-NIH Recovery Act Research Support: The goal of this STTR phase II effort is to develop a bioimage database and management system that is easy to use and provides sophisticated image processing and computer vision functionalities. The primary outcome of the parent project is a software that | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| INFORMATION IN PLACE INC | $46,715 | Grant | Trans-NIH Recovery Act Research Support: Design, Development, and Evaluation of Viyant HAZMAT eLearning Modules and Job Aids to Support Worker Health and Safety at Green Construction Sites. This supplement will enable our team to build these new just in time training modules and job aids for de | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| BIOINFORX, INC. | $77,164 | Grant | Trans-NIH Recovery Act Research Support: Though microarray experiments are very popular in life science researches, managing and analyzing microarray data are still challenging tasks for many biologists. Most microarray programs require users to obtain sophisticated knowledge of mathematics, sta | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| GT LIFE SCIENCES, INC. | $194,459 | Grant | Trans-NIH Recovery Act Research Support: Title: Model-driven Media and Process Optimization in Mammalian Cell Lines. Description: The overall goal of the project is to develop and validate a metabolic model-based platform for rational media and process optimization that significantly improves th | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| VIEW PLUS TECHNOLOGIES INC | $50,305 | Grant | Trans-NIH Recovery Act Research Support: The long range goal of this project is to provide authoring tools permitting graphical information to be exported from popular computer applications in a form that is universally usable by all people, in particular by people who are blind or who have othe | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| AZEVAN PHARMACEUTICALS INC | $226,385 | Grant | Trans-NIH Recovery Act Research Support: A POTENTIAL NEW DRUG FOR DEPRESSION Additional support was requested to broaden the scope of R44 MH063663, A Potential New Drug for Depression, an active SBIR Phase IIa award. The requested funds will allow additional characterization studies of three ne | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $336,375 | Grant | Trans-NIH Recovery Act Research Support: Specific B cells are stimulated to make antibody and memory B cells in germinal centers (GCs). These antibodies help protect people against infections diseases. We are studying molecules on a GC cell (follicular dendritic cells) that help regulate GCs. We | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $386,002 | Grant | Trans-NIH Recovery Act Research Support: The identification of a basic-rich motif in the cytoplasmic tail of the CD3e subunit could represent an important breakthrough in our understanding of how complex multi-subunit receptors are assembled, recycled, and signal. Preliminary results demonstrat | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $474,750 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of these studies is to define the innate host-virus interactions that occur during hepatitis C virus (HCV) infection with the hope that this will lead to novel therapeutic approaches to this disease. Using a robust cell culture model of | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF WASHINGTON | $115,674 | Grant | Trans-NIH Recovery Act Research Support: Targeted gene correction enlists a cell's own homologous recombination pathways to correct genetic deficiencies. Correction is targeted to the mutant gene by a DNA break, and templated by a correct copy of the mutant region, provided in trans. We are cu | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $78,101 | Grant | Trans-NIH Recovery Act Research Support: The specific aim is to generate glycosylated and non-glycosylated conserved and polymorphic domains of gp40 from major Cryptosporidium subtypes in order to investigate subtype-specific immune responses to these domains. | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $206,581 | Grant | Trans-NIH Recovery Act Research Support: HIV is a major pandemic of humankind. Little is understood about the early events of viral replication that occur soon after entry into the cells. This application is aimed at understanding how HIV is able to establish an infection in critical target ce | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $38,160 | Grant | Trans-NIH Recovery Act Research Support: The parent grant and this project focus on the role of cdk6 in thymocyte development and tumorigenesis. Using CDK6 knockout and knockin mice we made, we have found that cdk6 is an important regulator of T cell proliferation and development, and is crucia | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $50,460 | Grant | Trans-NIH Recovery Act Research Support: This is a supplemental application to DK067558 entitled Acinus: A Novel Corepressor of RAR-Regulated Gene Expression under the program for administrative supplements utilizing recovery act funds for summer research experiences for students and science ed | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $137,692 | Grant | Trans-NIH Recovery Act Research Support: Activation of eukaryotic transcription requires an orchestrated assembly of refined multi-protein complexes at chromatin-packaged genes. The long-term objective of our research is to elucidate the molecular mechanisms underlying eukaryotic transcription a | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $305,189 | Grant | Trans-NIH Recovery Act Research Support: Our original application (R01 HD048730, Stability of Epigenetic Structures in ART Children) had three specific aims centered on the hypothesis that Assisted Reproductive Technology (ART) can destabilize the establishment or faithful propagation of epigene | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OREGON SOCIAL LEARNING CENTER | $7,696 | Grant | Trans-NIH Recovery Act Research Support: Title: A Randomized Trial of a Mentoring Program for High Risk Children. The supplement enabled us to provide summer research experiences for students and benefitted the study at large by expediting our data collection and management efforts this summer | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $240,000 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement is to provide direct evidence of the intracellular location of the G protein-coupled estrogen receptor GPR30/GPER in neurons. Despite the recent acceptance of GPR30/GPER as an estrogen receptor by the scientific community, | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RFCUNY - CITY COLLEGE | $93,500 | Grant | Trans-NIH Recovery Act Research Support: Minority Biomedical Research Support - MBRS: To strengthen the biomedical research and research training capability of ethnic minority institutions, and thus establish a more favorable milieu for increasing the involvement of minority faculty and students | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE VANDERBILT UNIVERSITY | $126,498 | Grant | Trans-NIH Recovery Act Research Support: Vanderbilt University requests an Administrative Supplement to the Vanderbilt Biomedical Informatics Training Program for six Summer Research Experiences for each of two years: Year 1 G?? May 1, 2009 to April 30, 2010 and Year 2 G?? May 1, 2010 to April 3 | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF UTAH, THE | $134,168 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This is a competing continuation application for the Multidisciplinary Cancer Research Training Program (MCRTP) at the University of Utah. The MCRTP trains pre and postdoctoral scientists who will initiate independent | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $44,953 | Grant | Trans-NIH Recovery Act Research Support: This award provided for one funded position (ie, MD/PhD student) in our Medical Scientist Training Program. | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF WASHINGTON | $66,359 | Grant | Trans-NIH Recovery Act Research Support: Continuation of an ongoing interdisciplinary graduate training program in molecular biophysics at the University of Washington is sought. Support for the training of 13 predoctoral students per year is requested. Trainees will be selected competitively | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,604 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The University of Michigan proposes to continue predoctoral training in Molecular Biophysics, supporting in each year 12 Ph.D. students who will be part of the selected cohort of approximately 30 students in the Biophy | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $159,360 | Grant | Trans-NIH Recovery Act Research Support: The Universityof Michigan proposes to continue a predoctoral Chemistry-Biology Interface (CBI) Training rogram for a selected group of Ph.D. students. The number of students requested for this new training program is 10 for a five-year period of support. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $87,028 | Grant | Trans-NIH Recovery Act Research Support: This renewal application requests continuing support for the Molecular and Cellular Pharmacology Predoctoral Training (MCP) Program at the University of Wisconsin-Madison. Graduate training in pharmacology has been strong at Wisconsin for many decades and | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $157,928 | Grant | Trans-NIH Recovery Act Research Support: This project provides continued support of the Medical Scientist Training Program at the Medical University of South Carolina. The goal is to produce physician-scientists who choose a lifelong career in biomedical research spanning the interface between | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $74,418 | Grant | Trans-NIH Recovery Act Research Support: The sequencing of the human genome has set the stage for the next major frontier in biology, the proteome, and has paved the way for the new 'omics' era in biomedical reseach. The exploding cascadeof data requires integration of bioinformatics tools for d | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF NOTRE DAME DU LAC | $174,056 | Grant | Trans-NIH Recovery Act Research Support: The goals of the Chemistry-Biochemistry-Biology Interface (CBBI) Program is to train a highly qualified group of pre-doctoral students in an interdisciplinary environment that will provide them with significant cross-training at the interface of chemistry | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF ILLINOIS | $94,164 | Grant | Trans-NIH Recovery Act Research Support: The original award notice of NIH Training Grant T32GM079086-01, effective 7/1/09 for 5 years, showed an allotment for support for 2 students in year 1, 4 in year 2 and 6 in each of years 3, 4, and 5. When we received the 3rd year award notice, effective 7 | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $162,880 | Grant | Trans-NIH Recovery Act Research Support: BIOMEDICAL-BEHAVIORAL INTERFACE: PREVENTION AND DEVELOPMENTAL SCIENCES TRAINING This application proposes support for a program of interdisciplinary research training that interfaces the behavioral and biomedical sciences, with a cross-cutting theme empha | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $154,488 | Grant | Trans-NIH Recovery Act Research Support: These funds provide stipends, tuition, travel and training-related support for two Ph.D. students in the behavioral and biomedical sciences. Provision of these funds allows the students to devote full-time effort to their doctoral training. This include | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF PITTSBURGH THE | $174,056 | Grant | Trans-NIH Recovery Act Research Support: The objective of this predoctoral training program is to train the next generation of behavioral science researchers to skillfully incorporate neuroscience perspectives and methods into their programs of research, based on an understanding of brain struct | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CALIFORNIA STATE UNIVERSITY, FULLERTON | $64,092 | Grant | Trans-NIH Recovery Act Research Support: The goals are to provide research training of undergraduate paticipants, and to place and ensure the success of the participants in respected health-oriented graduate programs. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $47,779 | Grant | Trans-NIH Recovery Act Research Support: FIU is a public minority-serving research institution located in Miami. It has an enrollment of 38,000+ students (71.99% URM), health as a designated mission area, and a stated goal to be one of the nation's top public urban research universities. FIU pro | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY AUXILIARY AND RESEARCH SERVICES CORPORATION | $130,890 | Grant | Trans-NIH Recovery Act Research Support: A major goal of the CSUSM MARC Phase II Curriculum Improvement grant is to integrate quantitative and computational knowledge and skills throughout the entire undergraduate biology curriculum. Calculus is potentially an important tool for many science co | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $215,380 | Grant | Trans-NIH Recovery Act Research Support: In the fall semester 2011 a final testing of the revised MATH course for majors in the Biological Sciences was performed. Compiling of the results is underway and final assessment will be reported in the final report for the grant. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $441,958 | Grant | Trans-NIH Recovery Act Research Support: We are producing replicated lines of mice selectively bred for their propensity to high drinking in the dark (HDID). We are breeding mice for their high (>150 mg-%) BALs on the second day of 2 daily exposures to 20% ethanol for 2-4 h/day, starting in hr 3 | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $40,803 | Grant | Trans-NIH Recovery Act Research Support: This fund is an ARRA administrative supplement to 53311E entitled, 'A Multisite Neurobehavioral Assessment of Fetal Alcohol Spectrum Disorders.' The supplement will be used to hire undergraduate college students who will support the research efforts of th | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $803,600 | Grant | Trans-NIH Recovery Act Research Support: The Brooklyn WINS site is one of six clinical WIHS sites that together form the largest ongoing study of HIV infection in women in the US The WIHS in general, and the SUNY Brooklyn site in particular, have demonstrated their ability to recruit, retain and | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $885,989 | Grant | Trans-NIH Recovery Act Research Support: This award responds to RFA-CA-08-504 which is intended to continue support for Phase 1 and 2 treatment studies in adults with primary central nervous system cancers and to continue the activities that were funded initially under RFA CA-04-001. This single | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Prevention Program Outcomes Study (DPPOS) Diabetes Prevention Program (DPP) demonstrated that lifestyle and metformin reduce the risk of diabetes (DM) by 58% and 31% (NEJM 346;393-403,2002). The DPPOS, now in year 7, aims to determine whether re | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE MIRIAM HOSPITAL | $93,158 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | $100,630 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement to Look AHEAD will increase the scientific impact of Look AHEAD and retain and/or create new staff positions. Look AHEAD is a randomized, controlled, multi-center clinical trial comparing the long-term health effects of an in | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $114,660 | Grant | Trans-NIH Recovery Act Research Support: Chronic Kidney Disease is a silent epidemic affecting more than 10 million Americans. The burden of morbidity and mortality associated with chronic kidney disease derives from the frequent progression of chronic kidney disease to end-stage renal disease ( | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| DUKE UNIVERSITY | $369,999 | Grant | Trans-NIH Recovery Act Research Support: Liver injury caused by prescription drugs is the single most important reason for regulatory actions by the Food & Drug Administration, including failure to gain approval and removal from the market. These drug-induced liver injuries (DILIs) are usually i | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $100,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Diabetic gastropathy, presenting as nausea, vomiting, bloating, and pain, has been considered synonymous with gastroparesis as many patients exhibit delayed gastric emptying. Yet, emptying rates correlate poorly with s | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $149,994 | Grant | Trans-NIH Recovery Act Research Support: The Gastroparesis Clinical Research Consortium (GpCRC) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to focus on the etiology, natural history, and therapy of gastroparesis. The goal of this consortium is to | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WAYNE STATE UNIVERSITY (INC) | $267,999 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Primary vesicoureteral reflux (VUR) is a common problem, occurring [sic] in 8-50% of children with urinary tract infection (UTI). It has the potential for causing irreparable renal damage, particularly [sic] in younge | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| UNIVERSITY OF PITTSBURGH THE | $124,999 | Grant | Trans-NIH Recovery Act Research Support: Autosomal dominant polycystic kidney disease (ADPKD) is a major cause of disabling morbidity and is the fourth leading cause of end-stage renal failure in the world, affecting more than 500,000 Americans and millions more worldwide. CRISP I and II cohort | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $1,888,985 | Grant | Trans-NIH Recovery Act Research Support: The Pediatric HIV/AIDS Cohort Study (PHACS) was established to evaluate 2 critical areas in pediatric HIV research: the long-term safety of fetal and infant exposure to prophylactic antiretroviral (ART) chemotherapy, and the effects of prenatally acquired | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $160,058 | Grant | Trans-NIH Recovery Act Research Support: In October 2004, the U.S. Food and Drug Administration (FDA) issued an advisory that antidepressants may be associated with an increased risk of suicidal thoughts and behaviors in children and adolescents. These warnings were prompted by its meta-analysis | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| FRONTIER SCIENCE & TECHNOLOGY RESEARCH FOUNDATION, INC. | $785,220 | Grant | Trans-NIH Recovery Act Research Support: The E1508 randomized phase II clinical trial will evaluate the combination of cisplatin and etoposide versus cisplatin and etoposide with either GDC-0449 or IMC-A12 for selection of the regimen with superior anti-cancer activity (primary endpoint is progr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $789,614 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to facilitate accrual to RTOG 0539, 'A Phase II Trial of Observation for Low-risk Meningiomas and of Radiotherapy for Intermediate- and High-risk Meningiomas.' The awarded funds will be used to speed protocol development and activa | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| HEALTH RESEARCH, INC. | $181,655 | Grant | Trans-NIH Recovery Act Research Support: The NCI has released the latest Common Terminology Criteria for Adverse Events version 4.0 (CTCAEv4.0). In order to collect and report on these new criteria, database table(s) will need to be created, the new criteria will need to be loaded, mappings fro | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| FRONTIER SCIENCE & TECHNOLOGY RESEARCH FOUNDATION, INC. | $689,882 | Grant | Trans-NIH Recovery Act Research Support: This award funds a CTEP Initiative: ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT). The main objectives of this funding is to provide support for integration, standardization, and coordination of standardized informat | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NEW MEXICO | $317,201 | Grant | Trans-NIH Recovery Act Research Support: With the highest proportion of Hispanics and American Indians of any State (42% Hispanic, and 10% American Indian), New Mexico's 1.9 million people have tremendous cancer health disparities. Ranking only 47th in per capita income, New Mexico's population | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| WASHINGTON UNIVERSITY, THE | $1,301,816 | Grant | Trans-NIH Recovery Act Research Support: The Coordinating Center of the Ocular Hypertension Treatment Study (OHTS) has 3 specific aims to be completed within the 24 month funding period of the Recovery Act as follows: a. OHTS is the only randomized trial to compare the safety and efficacy of two | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $303,357 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will support the timely review of Serious Adverse Events in patients participating in the Lucentis Avastin clinical trial for neovascular age related macular degeneration. In addition, the reserach coordinator hired will pr | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| WAYNE STATE UNIVERSITY (INC) | $243,183 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the project is to complete and facilitate ongoing PPRU investigator initiated studies and to transfer legacy PPRU data into the PEDAR Database. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LOYOLA UNIVERSITY | $240,956 | Grant | Trans-NIH Recovery Act Research Support: This supplement will augment the activities and aims supported by the parent grant (5U10HD041250). Loyola University Chicago, Stritch School of Medicine (LUC-SSOM), has been a clinical site for 8 years in the Pelvic Floor Disorders Network (PFDN), a clini | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| DUKE UNIVERSITY | $252,254 | Grant | Trans-NIH Recovery Act Research Support: This proposal is responding to notice NOT-OD-09-056 of the NICHD's FY 2009 program for the American Recovery and Reinvestment Act (ARRA). The parent grant which serves as the umbrella from which this application originates is 5U10-HD041267. The proposed s | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $273,147 | Grant | Trans-NIH Recovery Act Research Support: In 2004, it is expected that over 1.3 million new cancer cases will be diagnosed and an estimated 563,700 Americans will die of this disease. The overall goal of our NCDDG program is to discover marine natural product leads for cancer chemotherapy. There | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| BROAD INSTITUTE, INC., THE | $611,323 | Grant | Trans-NIH Recovery Act Research Support: The goal of The Cancer Genome Atlas (TCGA) is to completely characterize the genomes of all human cancer types. During the past three years, the pilot project of TCGA has committed to studying 500 tumor/normal pairs of glioblastoma, serous adenocarcinoma | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF MASSACHUSETTS | $373,270 | Grant | Trans-NIH Recovery Act Research Support: The New England Consortium (TNEC), based at the University of Massachusetts at Lowell, received $373,270 to provide worker health and safety training courses related to the handling of hazardous materials and hazardous waste to students identified by work | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF CINCINNATI | $620,494 | Grant | Trans-NIH Recovery Act Research Support: The Midwest Consortium for Hazardous Waste Worker Training will conduct HWWT and HDPTP programs. In the HWWT program, HAZWOPER training will be provided in eight states of the Midwest and on the Reservation of The Three Affiliated Tribes. We will continue | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| CENTER FOR CONSTRUCTION RESEARCH AND TRAINING | $615,000 | Grant | Trans-NIH Recovery Act Research Support: Worker Health and Safety Training Cooperative Agreement. The purpose of this supplemental proposal is to provide additional safety and health training for our consortium partners, so that they will be able to provide trained workers for the projected inc | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF WASHINGTON | $1,954,800 | Grant | Trans-NIH Recovery Act Research Support: The NWRCE is receiving support for new projects from the recently signed American Recovery and Reinvestment Act (ARRA) in both FY09 and FY10. These projects are exceptionally innovative, and balance a greater than usual degree of scientific risk with the | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $3,365,340 | Grant | Trans-NIH Recovery Act Research Support: The New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research (NERCE) is one of eleven Region Centers across the nation support by the National Institute of Allergy and Infectious Diseases. Since its initial fundin | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $819,649 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application is to establish the Pacific Northwest Regional Center of Excellence (PNWRCE) in NIAID Region X. The two inter-related but distinct PNWRCE themes that we have selected reflect not only the scientific strengths at our institutio | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $81,347 | Grant | Trans-NIH Recovery Act Research Support: This funding contributes to using mass spectrometry to profile and identify adducts of human serum albumin (HSA) in lymphoma cases and controls and in smokers and nonsmokers. Although substantial progress has been made in detecting and profiling major HSA | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BAYLOR COLLEGE OF MEDICINE | $35,000 | Grant | Trans-NIH Recovery Act Research Support: PURPOSE: Equipment Acqusition. A Beckman-Coulter IC-100 High Throughput automated microscope will be acquired from the University of Texas, Southwestern, and moved to Houston for use in the Integrated Microscopy Core and as a resource for our NICHD U | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $136,437 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies take advantage of recent technical advances, animal models, and alternative strategies to implement methodological changes in Aims 1 and 3 that will expedite progress towards our research goals by increasing data quality and acquisiti | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $298,200 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to expand the community-based activites and infrastructure to pave the way to more intense community participation in the research activities of the PR-CCHD. This will be accomplished by an expansion of the community-base | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MASSACHUSETTS | $304,991 | Grant | Trans-NIH Recovery Act Research Support: The Patient Navigator supplement is an addition to the project staff for the UMB/DF-HCC U56 pilot entitled, Cancer Screening among Latinos in Churches. This community-based outreach pilot is funded by the U56 Developmental Core and began its final year of | Health and Human Services, Department of / National Institutes of Health | 7/01/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $418,361 | Grant | Trans-NIH Recovery Act Research Support: The Rockefeller University Center for Clinical and Translational Science proposes to create a comprehensive course in the area of Applied Bioinformatics for the further education of clinical researchers. The field of bioinformatics, which applies informat | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $288,300 | Grant | Trans-NIH Recovery Act Research Support: The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF IOWA, THE | $599,757 | Grant | Trans-NIH Recovery Act Research Support: An essential element of the RFA entitled Institutional Clinical and Translational Science Award, CTSA, is the creation of an academic home that is a department, center, or institute. In response to the RFA, the University of Iowa will create The Universit | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| WASHINGTON UNIVERSITY, THE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: This requested NCRR ARRA supplement submitted under the 'Enhancing NCRR Pilot Project Mechanism' priority provided funds to support two meritorious translational research projects selected from among the best scoring grant applications in Washington Unive | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| UNIVERSITY OF CHICAGO, THE | $598,128 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our community to determine the molecular underpinnings of disease or disease predisposition in | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $472,740 | Grant | Trans-NIH Recovery Act Research Support: The research proposed in this collaborative application Implementation and Evaluation of Formal Training for Mentors of K-Series Mentored Career Development Awards will uniquely study mentor training in the biomedical academic community with a level of sc | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF WASHINGTON | $590,641 | Grant | Trans-NIH Recovery Act Research Support: The University of Washington, the ITHS' home institution, serves as the medical school for five states -- Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI), providing the ITHS with enormous potential for collaboration and development of translationa | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $1,654,111 | Grant | Trans-NIH Recovery Act Research Support: The primary objective of the Translational Informatics and Data-management (TRIAD) Grid Project is to expand the scope and increase the pace of execution of programmatic efforts at The Ohio State University (OSU) Center for Clinical and Translational Scie | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $285,090 | Grant | Trans-NIH Recovery Act Research Support: The Harvard Catalyst Bioinformatics Program and Clinical and Translational Methods Linkages Program will: 1) improve the articulation of critical questions such that new individuals are attracted to the problem, 2) uncover the broadest possible community | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $981,624 | Grant | Trans-NIH Recovery Act Research Support: A partnership between the UAB Center for Clinical and Translational Science (CCTS) and 7 other CTSAs to develop a network of networks of practice-based physicians for conducting large-scale simple trials (LSTs) of therapeutics for chronic diseases using l | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $499,942 | Grant | Trans-NIH Recovery Act Research Support: One of medicine's greatest challenges today is the efficient, seamless translation of biomedical research discoveries into clinical applications. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $108,243 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the work to be supported by the requested administrative supplement will accelerate and expand the work plan contemplated under both randomized clinical trials in the HALT PKD network: 1) Maintain and retain a large HALT study populat | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $324,877 | Grant | Trans-NIH Recovery Act Research Support: The main hypothesis of the proposal is that a combination of anatomic and functional abnormalities of the arterial and venous circulations of the upper extremities, predict arteriovenous fistula maturation failure in patients with a stage 4 and 5 chronic | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| HARVARD PILGRIM HEALTH CARE INC | $447,156 | Grant | Trans-NIH Recovery Act Research Support: Nonpayment for Preventable Complications: Impact on Hospital Practices and Health Our long-term goal is to assess the overall impact of Medicare?s new policy of no longer paying hospitals for treating certain healthcare associated infections (HAIs) that | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $5,084,481 | Grant | Trans-NIH Recovery Act Research Support: This award, entitled ?Intracellular pathogens and innate immunity,? is a program project grant that consists of investigators from UC Berkeley, UCSF and Stanford Universities. There are four projects and three cores to support the research. Each investi | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $812,687 | Grant | Trans-NIH Recovery Act Research Support: Title: Imaging and Tissue Biomarkers in the Treatment of Brain Tumors. The aim of the Program Project is focused on the development of physiologic neuro-imaging methodologies and tissue biomarkers for the management of brain tumor patients with the ultim | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $294,200 | Grant | Trans-NIH Recovery Act Research Support: PURPOSE and OUTCOME: 1) To expand the Pilot/Feasibility (P/F) Program - We have transferred $20,000 to each of the three 2009 P/F awardees. We will also use funds to issue new P/F awards of $40-50,000 depending on budgetary needs of individual applicatio | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BUCK INSTITUTE FOR RESEARCH ON AGING | $807,226 | Grant | Trans-NIH Recovery Act Research Support: Aging is the single largest risk factor for disease in developed countries. The ongoing demographic change in the American population is greatly increasing the proportion of the population at risk for socially and economically significant age-related dise | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $49,999 | Grant | Trans-NIH Recovery Act Research Support: Cancer Center Support Grant - The ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring is intended to improve the efficiency and effectiveness of the clinical trials process and reduce costs, thereby realizing the goal of more rapid | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $150,000 | Grant | Trans-NIH Recovery Act Research Support: We are seeking administrative supplement funding to expand the scope and validate the new scope of Specific Aim 4 within our Cancer Nanotechnology platform grant. Specific objective within the the current grant entails: Investigation on the utility of AuN | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $401,722 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The insulin/insulin-like growth factor (IGF)-axis is a major regulator of cell proliferation/survival, and circulating IGF-axis protein levels are associated with the risk of several solid tumors, including tumors of t | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $998,815 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): RFA-03-CA-101. Challenge Area: Biomarker Discovery and Validation. Challenge Topic: Fingerprints for the Early Detection and Treatment of Cancer. Title: Early Functional Genetic and Epigenetic Changes in Human Lung Car | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $375,071 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $48,120 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Understanding energy balance and body weight regulation requires an understanding of the behavioral and neural evaluation of the oral and post-oral sensory signals involved in the control of food intake within a meal, | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $561,739 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to develop an approach that will improve the diagnosis of acute liver failure in infants, resulting in significantly improved outcome with medical therapy, and reduced utilization of liver transplantation in pediatric patients. Neonatal | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $1,249,535 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MONTEFIORE MEDICAL CENTER | $799,786 | Contract | : Recovery-ACTNOW Clinical Trial 8376 Early Therapeutics Development with Phase II Emphasis'. Purpose: To allot American Recovery and Reinvestment Act (AA) funds for the ACTNOW project entitled A Randomized, Phase II Study of FOLFOX in Combination with Be | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NATIONAL ASSOCIATES, INC. | $71,386 | Contract | : Temporary Clerical Support | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| LUCID INFORMATION DEVELOPMENT SOLUTIONS, LLC | $50,000 | Contract | : Provide technical writing support to review and process challenge grants. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| DJD CONSULTING | $48,000 | Contract | : Technical Review of Assurance and Related Documents | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $112,482 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We will evaluate the association between growth failures (GF) in children, and sleep disordered breathing (SDB) characterized by snoring, apnea, and mouth-breathing. Adenotonsillar hypertrophy is the primary factor lea | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $876,120 | Grant | Trans-NIH Recovery Act Research Support: The identification of ultraconserved non-coding sequences in vertebrates has been associated with developmental regulators and DNA binding proteins. One of the first of these was identified in the intergenic region between the Dlx-5 and Dlx-6 genes, memb | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $15,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement application is to request salary support for a summer research experience for undergraduate students in 2009 and 2010. The funding will allow students to help to conduct research through a parent grant (R01 A | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $266,184 | Grant | Trans-NIH Recovery Act Research Support: Project title: Protein Function Prediction by Statistical Phylogenomics ? ARRA Administrative Supplement Summary: Prediction of protein functions facilitates understanding the role human proteins have in maintaining health, as well as elucidating the fu | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $242,753 | Grant | Trans-NIH Recovery Act Research Support: 1A. Bioinformatically define targets of miR-21 and miR-196b, then identify those that are expressed in myeloid progenitors. 1B. Define the sensitivity of these targets to miR-21 and miR-196b knockdown through a luciferase-sensor assay (luciferase tagge | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $242,069 | Grant | Trans-NIH Recovery Act Research Support: Overall Purpose - Fanconi anemia (FA) is a recessive genetic instability syndrome that has uncovered a cellular pathway involved in the protection against replication-blocking lesions. Inactivation of this pathway, as seen in FA patients, results in | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $87,832 | Grant | Trans-NIH Recovery Act Research Support: Purpose This ethnographic study involving up to 30 participants explores patients socio-cultural context at the time of clinical trial (CCT) decision-making to identify how and when the Cancer Information Service can provide appropriate informational supp | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: PI left UCSF as of 10/31/09. Project has filed for early termination. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $298,193 | Grant | Trans-NIH Recovery Act Research Support: The ARRA supplement to the IRACDA Scholars in Science (ISIS) parent grant enables UCSF to increase the number of ISIS Fellows who benefit from mentored teaching and career-enhancing training. The supplement also provides current ISIS Fellows with the opp | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF MASSACHUSETTS | $207,325 | Grant | Trans-NIH Recovery Act Research Support: The supplemental funds requested would be used to accelerate the tempo of scientific research on antibiotic resistance and more rapidly research the position where translational research is possible. The translation of this basic research into application | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MASSACHUSETTS | $46,629 | Grant | Trans-NIH Recovery Act Research Support: Maintaining proper cellular levels of metal ions is key to the survival of all organisms. The viability of bacteria, including human pathogens, has been linked to the ability to acquire or compete for transition metals. Several human diseases have been sh | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| VILLANOVA UNIVERSITY IN THE STATE OF PENNSYLVANIA | $228,898 | Grant | Trans-NIH Recovery Act Research Support: Study of the health related adjustments of adult females who experienced childhood cancer. | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $404,592 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Chronic disease management is the biggest health care problem facing the United States today. Chronic diseases especially affect older adults, 80% of older adults have at least one chronic condition and 50% have two or | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| ILLINOIS INSTITUTE OF TECHNOLOGY | $386,824 | Grant | Trans-NIH Recovery Act Research Support: Funds were requested as an administrative supplement using ARRA funds in order to ?accelerate the tempo of scientific research? by providing additional effort for the ProjectBioCAT - Biophysics Collaborative Access Team from NCRR with an emphasis on aims | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF ILLINOIS | $476,276 | Grant | Trans-NIH Recovery Act Research Support: The principal aim this Administrative Supplement request is to increase the pace of discovery of novel phosphonate antibiotics by enhancing our ongoing microbial screening program. The proposed supplement would be used to fund the immediate screening of t | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $225,570 | Grant | Trans-NIH Recovery Act Research Support: This supplement supported seven high school students, two undergraduate students, and two teachers in a Summer Research Experience in the Lim lab at UCSF to teach research skills. | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $767,188 | Grant | Trans-NIH Recovery Act Research Support: The movement of cells and organisms toward or away from chemicals, chemotaxis, is a crucial behavior for their survival that requires sensitive information detection and processing. Bacterial chemotactic behavior has been intensively studied for nearly 40 | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| UNIVERSITY OF MARYLAND | $53,730 | Grant | Trans-NIH Recovery Act Research Support: Research objectives: The studies that Javier Robalino will conduct will fully integrate into the objectives of the parent grant. We propose to identify natural inducers of antiviral immunity in Drosophila. We will focus on testing the potential of virus-d | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $712,293 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Manipulation of Macrophage Responses by M. tuberculosis. This grant provided funding for studies on the molecular basis of tuberculosis pathogenesis to determine the pathogen and host factors responsible for innate immune signaling during | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $213,217 | Grant | Trans-NIH Recovery Act Research Support: Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disease with deregulated expression of the fusion gene p210-BCR-ABL. Molecular targeting of p210-BCR-ABL by inhibiting the abl kinase activity with Imatinib or other agents can suppress gro | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $171,970 | Grant | Trans-NIH Recovery Act Research Support: This award provides salary support for a graduate student, Mardi Sutherland. Mardi is using a conditional mouse model of Zic3 to study the tissue and developmental stage specific requirement for Zic3. In this quarter, Mardi has been testing the efficiency | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CENTRAL FLORIDA | $1,310,275 | Grant | Trans-NIH Recovery Act Research Support: Research spanning more than two decades consistently has demonstrated the positive benefits of physical activity in the primary and secondary prevention of chronic diseases such as cardiovascular disease, cancer, obesity, diabetes, osteoporosis, depressio | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $63,900 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Administrative Supplement application for the parent grant R01NS050536: Drug and Non-Drug Treatment of Pediatric Chronic Headache is to enhance the activity of this randomized clinical trial by increasing the rate of enrollment, increa | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $305,539 | Grant | Trans-NIH Recovery Act Research Support: Grant Name: Neural Mechanisms Underlying Cognitive Aging: The goal of the parent R01 is to identify alterations in fundamental neural mechanisms that underlie a wide range of age-related cognitive deficits, so that we can generate a unifying cognitive ag | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,408,606 | Grant | Trans-NIH Recovery Act Research Support: The Impact of Early Antiretroviral Therapy in HIV Persistence grant aims to determine the effect of early versus delayed HAART on viral persistence, and to determine the association between high-through put measures of low level viral load and amount of r | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $464,598 | Grant | Trans-NIH Recovery Act Research Support: Currently, there is great interest in the idea of personalized therapy for cancer, based on the notion that each patient's cancer is distinct. However, there remains substantial evidence that cancers also share common, obligate elements that, if adroitly | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $470,456 | Grant | Trans-NIH Recovery Act Research Support: Breast cancer is the second leading cause of cancer deaths in women and is the most common cancer among women. The primary cause of death in breast cancer is metastasis, a process that is still poorly understood, and it is still not possible to accurately | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $765,388 | Grant | Trans-NIH Recovery Act Research Support: The title of the project is Resolving microRNA Targets. The nature of small RNA biology is not well understood, and there is a need to develop additional tools to interrogate the factors involved. MAJOR GOAL - The goal of this proposal is to identify mi | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $718,000 | Grant | Trans-NIH Recovery Act Research Support: Grant Name: Selective Ablation of Dental Caries and Composites. The overall objective of this research is to increase our fundamental understanding of the interaction of high intensity laser radiation with dental hard tissues and apply that knowledge to d | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| KANSAS STATE UNIVERSITY | $257,674 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to fund sequencing of the Manduca sexta genome, which will provide data that will substantially accelerate progress on the aims of the parent grant. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND | $81,255 | Grant | Trans-NIH Recovery Act Research Support: This supplemental effort will enable substantial acceleration of our work on the modeling and design of low molecular weight receptors (hosts) with biomedical applications. In the course of the existing project, we have developed unique software for rapi | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| VAN ANDEL RESEARCH INSTITUTE | $764,398 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of this project are to unravel the structural basis of hormone binding and activation of the family of Class B G-protein-coupled receptors (GPCRs) and to explore the obtained structural information with a goal toward rational desi | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ARIZONA STATE UNIVERSITY | $581,750 | Grant | Trans-NIH Recovery Act Research Support: High-throughput analysis has become an essential tool in biomedical informatics and genomic research. One aspect of this research paradigm that has not been heavily examined is how errors generated in early stages of these analyses propagate through downs | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $164,267 | Grant | Trans-NIH Recovery Act Research Support: The goal is to provide funding for personnel and technology for 2 major enhancements to main grant, incl. active recruit. of subjects with acute HIV infection, & process. & analysis of diffusion tensor imaging obtained in primary infection subjects. | Health and Human Services, Department of / National Institutes of Health | 3/31/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $124,914 | Grant | Trans-NIH Recovery Act Research Support: Immigrant children living in poverty are disproportionately exposed to family, economic, cultural, and community adversities. The autonomic nervous system (ANS) responds to adversities by activating the sympathetic nervous system (flight or fight respons | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CARNEGIE MELLON UNIVERSITY | $153,500 | Grant | Trans-NIH Recovery Act Research Support: Sustained selective attention underlies our ability to process some parts of the environment at the exclusion of others over a period of time. Therefore, sustained selective attention is a crucially important process enabling one to process relevant infor | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $397,530 | Grant | Trans-NIH Recovery Act Research Support: Fungal infections are increasingly important, often fatal complications of intrusive medical procedures ranging from the sustaining therapies for neonates to bone marrow transplantation, chemotherapy and deep surgical procedures. This study is designed t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $345,003 | Grant | Trans-NIH Recovery Act Research Support: Purpose: The aim of the HEARTS study is to better understand the distribution and correlates of Human Papilloma Virus (HPV) among homeless and unstably housed women. Goal: The overall goal of the study is to provide population-specific inform for pre | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| BANYAN BIOMARKERS INC. | $30,351 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the current Summer Student Research Experiences Administrative Supplements to Svetlov-SBIR grant (5R44DK074205-03) is to develop experimental data on systemic and topical use of ASS to clear the body of bacterial toxins and accele | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $889,218 | Grant | Trans-NIH Recovery Act Research Support: The G?SystemsG? approach aims to capitalize on the dramatic advances in proteomics, genomics, and measurement technologies such as DNA arrays to generate a holistic understanding of biological organisms. Systems biology approaches can be profitably exploi | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: One of the major unsolved problems in drug delivery is how to transport poorly permeable molecules across membrane barriers and release them in specific cells or tissues. The way that Nature solves this problem is through membrane trafficking; cell imperm | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $999,999 | Grant | Trans-NIH Recovery Act Research Support: Grant Name: Determinants of Participation in an Anal Cancer Prevention Trial (IMPACT) The incidence of anal cancer among people with HIV is higher than cervical cancer was before routine cervical cytology screening was introduced, but unlike cervical can | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $4,131,403 | Grant | Trans-NIH Recovery Act Research Support: Advances in basic science research over the past 20 years have created new opportunities for targeted therapies for TBI, but such advances have failed to translate into successful clinical trials or treatments. Improving the quality of healthcare delivery | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $304,846 | Grant | Trans-NIH Recovery Act Research Support: The broad, long-term objective of the work proposed herein is to validate a novel strategy for anti-cancer therapy. A hallmark of cancerous cells is their ability to resist apoptosis and become immortal. This resistance is typically due to mutations in or | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ILLINOIS | $374,020 | Grant | Trans-NIH Recovery Act Research Support: A central interest in developmental, reproductive, and stem biology is how common precursor cells acquire instruction to differentiate into specialized cell types in various organs. Understanding how cell fates are determined not only satisfies the curios | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $932,481 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this application is to continue operation of the National Swine Resource and Research Center (NSRRC). To date, the NSRRC is just beginning its fourth year of operation and it has successfully developed the infrastructure needed to assi | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $2,782,895 | Grant | National Center for Research Resources, Recovery Act Construction Support: To renovate existing research facilities and build new research facilities to meet basic and clinical space requirements, laboratory safety, biohazard containment, and animal care standards in order to support the facility dememands of NIH research programs... Show more | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $305,079 | Grant | Trans-NIH Recovery Act Research Support: The highly polymorphic HLA class I and II genes play an essential role in immune recognition, and underlie susceptibility to autoimmune diseases [1]. In particular, multiple associations between HLA alleles and rheumatoic diseases, including rheumatoid ar | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $134,606 | Grant | Trans-NIH Recovery Act Research Support: The Multicenter Osteoarthritis Study (MOST) received an NIA ARRA (American Recovery and Reinvestment Act) Administrative Supplement in order to relocate the MOST biospecimens to a reliable commercial repository to facilitate quality assurance for long-ter | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MARYLAND MEDICAL RESEARCH INSTITUTE, INC. | $423,600 | Grant | Trans-NIH Recovery Act Research Support: Silent Cerebral Infarct Multi-Center Clinical Trial - SCC | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $1,103,695 | Grant | Trans-NIH Recovery Act Research Support: Molecular Genetics of HLA and Disease: Our overall objective is to advance the understanding of autoimmunity through genetic analysis of the polygenic Human Leukocyte Antigen (HLA) locus, the strongest genetic factor identified as influencing risk for aut | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $280,753 | Grant | Trans-NIH Recovery Act Research Support: The NIH Human Endometrial Tissue and DNA Bank, a national resource founded in 2000, resides in our NIH U54 SCCPIR Center at UCSF and serves as a repository for human endometrial tissue, DNA, and blood specimens for SCCPIR and other NIH investigators. To | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| XCISION MEDICAL SYSTEMS, LLC | $399,912 | Grant | Trans-NIH Recovery Act Research Support: We propose to increase 1.4 FTE to improve the quality and accelerate the development of the planning system and treatment device. The proposed projects will also strengthen the quality processes to ensure a timely FDA submission, which, in turn, will brin | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| INFOSCITEX CORPORATION | $51,348 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience(s) for 9 college students and 1 science educator in health?related scientific research. The college students were: Meixin Wang, Prasant Varghese, Debra Leong, Ranjan Upadhyay, David Shiovitz, Jennifer Wang, | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $453,601 | Grant | Trans-NIH Recovery Act Research Support: he recent passage of the Paul Wellstone and Pete Domenici Mental Health Parity and Addiction Equity Act of 2008, which requires private health plans to provide equal coverage of behavioral and medical/surgical services, also known as parity, represents an | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $87,890 | Grant | Trans-NIH Recovery Act Research Support: Candidate: Jonathan Mansbach, MD is an Instructor in Pediatrics at Harvard Medical School at Children's Hospital Boston (CHB). He supervises an inpatient pediatric service and works with his mentor, Carlos A. Camargo, MD, DrPH, conducting bronchiolitis re | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| RESEARCH TRIANGLE INSTITUTE | $411,222 | Grant | Trans-NIH Recovery Act Research Support: This project will refine an intervention to reduce sexual and injection risk behaviors that lead to infection with HIV and other sexually transmitted infections (STIs) and the hepatitis C virus (HCV) for use in rural areas. The intervention features a sy | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $233,947 | Grant | Trans-NIH Recovery Act Research Support: The long term objective of our studies is to understand the gene regulatory networks that define pancreatic multipotent progenitor cells (MPCs). This knowledge will provide new insights into the biology of MPCs and also assist in the validation of protoc | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| INTERNATIONAL CHEMICAL WORKERS CREDIT UNION | $403,044 | Grant | Trans-NIH Recovery Act Research Support: The ICWUC CenterG??s ARRA efforts are centered on expanding the emergency/response/ disaster community and worker training by working with CBTU's National Priority Issues that disproportionately impact minority communities including Emergency Response, Wa | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| INTERNATIONAL UNION OF OPERATING ENGINEERS NATIONAL TRAINING FUND | $441,000 | Grant | Trans-NIH Recovery Act Research Support: This award includes an administrative supplement of $441,000 total costs to provide hazardous waste worker training to target populations in emerging health and safety areas associated with green construction and green building operations. A universal gr | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| DILLARD UNIVERSITY | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The Historically Black Colleges and Univeristy(HBCU) Consortium consists of Dillard University's Deep South Center for Environmental Justice(New Orleans) in partnership with Clark Atlanta Univeristy Environmental Justice Resource Center(Atlanta, GA) The m | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH | $261,473 | Grant | Trans-NIH Recovery Act Research Support: The use of appropriate point-of-care (POC) diagnostic tests can mean the difference between the right treatment or continued sickness or death: In low-resource settings (LRS), especially in developing countries, diagnostic capabilities are minimal, inadeq | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| POPULATION COUNCIL, INC., THE | $296,447 | Grant | Trans-NIH Recovery Act Research Support: The goals of the Cooperative Contraceptive Development Research Center are to identify and further develop new leads that look promising as safe and effective contraceptive methods for men and women. The five approved projects address unmet needs in contr | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHARLES DREW UNIVERSITY OF MEDICINE AND SCIENCE | $169,968 | Grant | Trans-NIH Recovery Act Research Support: Through this Research Center for Minority Institutes (RCMI) Clinical Research Infrastructure Initiative (RCMI-CRC) supplement, Charles Drew University of Medicine and Science (CDU) will expand upon the CRC mission by developing future investigators from d | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| NORTHEASTERN UNIVERSITY | $29,999 | Grant | Trans-NIH Recovery Act Research Support: Femtosecond Coherence Spectroscopy and Ultrafast Kinetic Investigations of HemeP | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $4,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The purpose of this grant is to obtain is to build essential infrastructure improvements to enhance the quality of animal research and care at the Sabana Seca Field Station of the Caribbean Primate Research Center (CPRC). The e materials and equipment that ... Show more | Health and Human Services, Department of / National Institutes of Health | 10/20/2009 |
| BIOMEDICAL RESEARCH INSTITUTE OF NEW MEXICO | $57,404 | Grant | Trans-NIH Recovery Act Research Support: Project Title: -?-?C-reactive protein suppresses the immune system through Fc gamma receptors.-?-? Grant Number: 5F31AI080178-02 A great deal of the original work that was proposed in the original grant application was published: Kristopher D Marjon, Lor | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $102,208 | Grant | Trans-NIH Recovery Act Research Support: The goal of this Ruth L. Kirschstein National Research Service Award for Individual Postdoctoral Fellows is to understand the mechanisms involved in chromatin-mediated regulation of gene expression. We will use herpes simplex virus-1 (HSV-1) to investigat | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| BATTELLE MEMORIAL INSTITUTE | $935,351 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Visual Analytics Software Environment for Proteomics Data Integration Award Purpose: The continued development and maintenance of visual analytics software providing a multi-resolution environment that can currently integrate genomic and p | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UT-BATTELLE, LLC | $82,178 | Grant | Trans-NIH Recovery Act Research Support: NIH Grant Number -- 1R01GM088501-01: Accurate Mass Analysis of Singly-Charged Intact Proteins: This award provides funding from the National Institutes of Health (NIH). Our goal is analysis of singly-charged intact proteins and complexes with part-per- | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF PITTSBURGH THE | $189,375 | Grant | Trans-NIH Recovery Act Research Support: Alcohol abuse and consumption are major causes of liver disease and is a major health problem in the United States. The characteristics of this disease are fatty liver, hepatitis, fibrosis, and cirrhosis. Cirrhosis is the eleventh leading cause of death i | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $274,940 | Grant | Trans-NIH Recovery Act Research Support: We propose the acquisition of Bioptigen, Inc. 840 nm SDOCT Optical Coherence Tomography (OCT) bundled with Phoenix Research Laboratories, Inc. Micron III Retinal Imaging Microscope package (total cost $274,940) for use with both humans and other animals. | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| UNIVERSITY OF NOTRE DAME DU LAC | $144,480 | Grant | Trans-NIH Recovery Act Research Support: Characterization of protein conformational changes is a crucial pre-requisite to understanding biological functions on a molecular level. Circular dichroism (CD) spectroscopy has been an essential component of the biophysical tool kit for decades, exploit | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF CHICAGO, THE | $420,000 | Grant | Trans-NIH Recovery Act Research Support: Cytometry, at its core understanding, requires the ability to measure many characteristics of cells and sub- cellular structures for the purpose of understanding the function of proteins within a cell, cell subtypes within a population, and subsequently t | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $247,658 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to bring a new genetic technology, the BioMark MX/HX Genetic Analysis System, to our shared instrument facility as a tool in the many genetic analysis projects that are performed in this facility. The BioMark is a high throughp | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| UNIVERSITY OF NEBRASKA | $125,000 | Grant | Trans-NIH Recovery Act Research Support: The main purpose of this proposal is to use the allocated funds for the purchase of an ultrasensitive iTC200 microcalorimeter from GE Healthcare, Microcal Products Group. This isothermal titration calorimeter (ITC) is capable of measuring complete therm | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| NATIONAL JEWISH HEALTH | $499,998 | Grant | Trans-NIH Recovery Act Research Support: This application is for an iCyt Reflection System Fluorescence Activated Cell Sorter to be housed in the Flow Cytometry and Microscopy core Facility at National Jewish Health. National Jewish investigators have extensive experience in cell sorting, and 22 | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $482,451 | Grant | Trans-NIH Recovery Act Research Support: Funds are requested to purchase a VisualSonics Vev02100 phased array small animal ultrasound imaging system - including transducers appropriate for cardiovascular, cancer, nephrology and diabetes research. High resolution ultrasound is the preferred modal | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $500,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This project will establish a modern environmental SEM platform and automated ultramicrotome system for serial block-face scanning electron microscopy (SBFSEM) at the National Center for Microscopy and Imaging Research | Health and Human Services, Department of / National Institutes of Health | 12/24/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $498,925 | Grant | Trans-NIH Recovery Act Research Support: The University of Virginia School of Medicine currently has an obsolete 40-year-old orthovoltage XRAY machine which is used for irradiation of small animals. This proposal is to replace our obsolete irradiator with a state of the art small animal radiatio | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| OHIO STATE UNIVERSITY, THE | $3,920,956 | Grant | National Center for Research Resources, Recovery Act Construction Support: This C06 research facilities construction proposal seeks to renovate research facilities to enhance a group of well-bonded investigators that use integrated models to elucidate basic cellular mechanisms of human infectious didisease. The recent funding of ... Show more | Health and Human Services, Department of / National Institutes of Health | 10/16/2009 |
| STERN MAGNETICS, LLC | $183,490 | Grant | Trans-NIH Recovery Act Research Support: Phase I SBIR | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| SOCIOMETRICS CORPORATION | $999,995 | Grant | Trans-NIH Recovery Act Research Support: The proposed project directly addresses the need for evidence-based, culturally relevant drug prevention interventions that are accessible and engaging to Native American youth in remote locations. We propose to make use of the latest advances in informat | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BETASTEM THERAPEUTICS INC | $996,184 | Grant | Trans-NIH Recovery Act Research Support: Our specific aims will determine the best time in the natural history of the disease to treat the patient, identify the ideal EPC population to use for therapy, and determine the best method of delivery to the eye. In this proposal, we are using a combina | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HEALTH RESEARCH, INC. | $4,675,896 | Grant | National Center for Research Resources, Recovery Act Construction Support: This NTH construction application is requesting $2,401,705 to renovate the third and three-quarters of the fourth floor (20,763 net sq. ft) in the 30-year-old, 5-story Cancer Cell Center building (CCC) at Roswell Park Cancer I Institute (RPCI) for occupancy... Show more | Health and Human Services, Department of / National Institutes of Health | 10/20/2009 |
| YALE UNIVERSITY | $898,724 | Grant | Trans-NIH Recovery Act Research Support: This high-end instrument grant is to request funds for an iCyt Reflection Cell Sorter that will be dedicated for Biosafety Level 3 (BSL3) research at Yale University School of Medicine as a shared instrument amongst greater than 15 labs. In response to th | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| JOSLIN DIABETES CENTER, INC. | $496,494 | Grant | Trans-NIH Recovery Act Research Support: G?COPAS BIOSORT Flow CytometerG? During the last 30 years, the technology of fluorescence-activated cell sorting has enabled countless breakthroughs in many fields. In an exciting technological leap, this concept has recently been extended to include sor | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| SOUTH DAKOTA STATE UNIVERSITY | $367,958 | Grant | Trans-NIH Recovery Act Research Support: This project is to study antitoxin vaccines against enterotoxigenic Escherichia coli (ETEC) diarrhea disease using a pig model. Heat-labile (LT) and heat-stable (STa) enterotoxins produced by ETEC are the virulence determinant in ETEC diarrhea. Antitoxi | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| RIGAKU AMERICAS CORPORATION | $179,300 | Contract | : CCD X-Ray Detector accessories | Health and Human Services, Department of / National Institutes of Health | 11/12/2009 |
| UNIVERSITY OF LOUISVILLE | $811,389 | Grant | Trans-NIH Recovery Act Research Support: This is a request to provide funding for a bioinformatics faculty member with a specialty in eipgenetics. This request is put forward by the University of Louisville Alcohol Research Center (ULARC-NIAAA-funded P01AA017103-01- PI) and the new faculty lin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF LOUISVILLE | $739,441 | Grant | Trans-NIH Recovery Act Research Support: Alcoholic liver disease (ALD) is an important health problem, but an FDA-approved effective therapy is not available. Although previous studies have largely focused on the direct effects of ethanol on the liver, clinical evidence indicates that excessive | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $699,968 | Grant | Trans-NIH Recovery Act Research Support: This award is to study the mechanism of necroptosis, a novel programmed necrotic cell death pathway, in cancers. Our study focuses on the initiation of signaling mechanism of necroptosis that occur with the receptor of TNFalpha. (TNF = Tumor necrosis fact | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OHIO STATE UNIVERSITY, THE | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: The major goal of the Biomedical Research Tower (BRT) is to create a multidisciplinary biomedical research and education center for The Ohio State University Medical Center (OSUMC) that will be a centerpiece of a dramaticallyly enhanced health sciences cam... Show more | Health and Human Services, Department of / National Institutes of Health | 10/16/2009 |
| UNIVERSITY OF NEBRASKA | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: A facility for the Nebraska Center for Virology (NCV), an NCRR Center of Biomedical Research Excellence, is the highest facility construction priority of the University of Nebraska-Lincoln (UNL). NCV scientists conduct basic r research on human, animal, and... Show more | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| BOISE STATE UNIVERSITY | $3,978,104 | Grant | National Center for Research Resources, Recovery Act Construction Support: An introduction to the revisions contained in this application may be found in the following section. To become a 'metropolitan research university of distinction' is the goal of the president of Boise State University (BSU). . To become a Carnegie Research... Show more | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $2,786,306 | Grant | National Center for Research Resources, Recovery Act Construction Support: The objective of this application is to obtain matching funds to integrate and enlarge space for the existing Drug Discovery Core Facility (DDCF) of the Pennsylvania State University College of Medicine (PSUCOM). Drug discovevery and development are the na... Show more | Health and Human Services, Department of / National Institutes of Health | 10/20/2009 |
| UNIVERSITY OF DELAWARE | $8,000,000 | Grant | National Center for Research Resources, Recovery Act Construction Support: This award, McKinly Laboratory Animal Facility Renovation And Expansion, will pay for construction of a new animal facility to support basic research in biomedical and behavioral science at the University of Delaware. The resusult will be a large increase i... Show more | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| YALE UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Olfactory receptors (ORs) are seven-transmembrane chemosensors which are responsible for the initial step of odorant detection in the olfactory epithelium. Recently, ORs have also been found to play a role in chemosensation in non-olfactory tissues. Howev | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| YALE UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The majority of emerging infectious diseases that affect humans are zoonotic; diseases that are transmittable between animals and humans. The health of animals can be a sentinel for zoonotic diseases in humans. Unfortunately, most local and state health d | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| YALE UNIVERSITY | $84,200 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this Program Project is to understand the mechanisms underlying renal fluid and electrolyte homeostasis and renal epithelial function in health and the processes that modulate these mechanisms in disease. A broad spectrum of techniques | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| YALE UNIVERSITY | $331,000 | Grant | Trans-NIH Recovery Act Research Support: The Yale Diabetes Endocrinology Research Center was established in the Spring of 1993 with the goal of promoting research in diabetes and related metabolic and endocrine disorders at the University. The Center brings together a multidisciplinary group of | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| YALE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The proximal tubule reabsorbs low molecular weight protein (less than 70 kDa) that passes the glomerular filtration barrier by a mechanism that is largely dependent on the scavenger receptor megalin. In the healthy adult this amounts to as much as 0.6-5.0 | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| YALE UNIVERSITY | $67,281 | Grant | Trans-NIH Recovery Act Research Support: We have created an allelic PTHrP-lacZ knockin mouse that provides a simple and sensitive reporter of PTHrP gene expression. The PTHrP-lacZ mouse demonstrates PTHrP gene expression in a wide variety of locations, including several that were previously unap | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| YALE UNIVERSITY | $26,045 | Grant | Trans-NIH Recovery Act Research Support: The lateral hypothalamus (LH) serves as a central hub, integrating a wide range of inputs from various brain regions and projecting neuropeptide-containing nerve fibers all over the brain. The LH has long been recognized as a feeding center. The regulatio | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $92,600 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Recovery Act Administrative Supplement is to accelerate the pace of research on the parent NIH grant 5R01DK042921-17 entitled ?Regulation of Kidney-Specific Gene Expression.? The goal of the parent grant is to understand the roles of t | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $90,500 | Grant | Trans-NIH Recovery Act Research Support: We continue our efforts to recruit additional pedigrees with various types of genetic lipodystrophies to ascertain those which are not linked to the known loci. These include pedigrees with congenital generalized lipodystrophy familial partial lipodystrop | Health and Human Services, Department of / National Institutes of Health | 12/26/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Quantifying the extent of interactions between different PDK isoforms and the inner lipoyl-bearing domain and between PDK4 and novel PDK4 specific inhibitors. These experiments are designed to corroborate the proposed allosteric model for the regulation | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| LOS AMIGOS RESEARCH AND EDUCATION INSTITUTE, INC. | $124,138 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to accelerate the rate of data collection, processing, and analysis of the biomechanical parameters of wheelchair propulsion while continuing our efforts in subject recruitment and retention in our on-going research project. | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $184,659 | Grant | Trans-NIH Recovery Act Research Support: Without large population studies, the promise of the Human Genome project and personalized genomic medicine will remain unfulfilled in significant ways. Sufficiently large numbers of individuals from a wide variety of backgrounds enrolled in cohort studie | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| WILDLIFE TRUST INC. | $51,225 | Grant | Trans-NIH Recovery Act Research Support: This application for supplements addresses NOT-OD-056, Fogarty ARRA Administrative Supplement for Support of Information and Communication Technology Initiatives in Research and Research Training Programs. In the parent grant, we propose a series of stud | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF LOUISVILLE | $18,254 | Grant | Trans-NIH Recovery Act Research Support: Quarterly Activities/Project Description:This administrative supplement is to provide summer research experience for two undergraduate students. The other purpose of the supplement is to accelerate our research on the migration of pancreatic cancer cells. | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| SAINT LOUIS UNIVERSITY | $44,966 | Grant | Trans-NIH Recovery Act Research Support: This supplement would provide a modern liquid scintillation counter, a machine that will aid in metabolic measurements, to support an ongoing NIH-funded project. The proposal meets the aims of the ARRA by providing funds that would be rapidly spent on equ | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| OHIO UNIVERSITY | $34,185 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement seeks funds to accelerate the tempo of the parent AREA grant and to refine several of the studies through the use of new technology. The overall research goal of the parent grant is to study the relationship between growth | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| GEORGETOWN UNIVERSITY (THE) | $45,000 | Grant | Trans-NIH Recovery Act Research Support: The long term objective of this project is to understand the relationship between the regulation of gene expression and nuclear substructure. Recent reports indicate that, soon after they are transcriptionally induced, genes in the model eukaryote Sacchar | Health and Human Services, Department of / National Institutes of Health | 1/01/2010 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: A. SPECIFIC AIMS The Specific aims of the project are; Aim 1: To test the effectiveness of the Experimental Intervention on reducing BMI z-score compared to the control intervention. Aim 2: To test the effects of the Experimental Inten/ention compared to | Health and Human Services, Department of / National Institutes of Health | 12/29/2009 |
| DUKE UNIVERSITY | $99,999 | Grant | Trans-NIH Recovery Act Research Support: E.coli induced Urinary tract infections (UTIs) constitute one of the most common bacterial infections of man. Because of the recurrence of UTIs in infected patients and the growing resistance of E.coli to antibiotics, there is great interest in developing | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $72,867 | Grant | Trans-NIH Recovery Act Research Support: In this administrative supplement to the parent grant, 1 R21 DK078368 01A2 (Magnesium and the Metabolic Syndrome Trial [MMST]), we propose to: 1. Expedite goals of the parent grant by increasing percent effort of the Principal Investigator (PI) and Co In | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF MARYLAND | $56,521 | Grant | Trans-NIH Recovery Act Research Support: The parent grant (R37 DK42495-20) associated with this application focuses on the role of gap junctions that confer syncytial properties to renal medullary descending vasa recta (DVR) endothelium. DVR are microvessels, 12 to 15 micron branches of juxtamed | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $976,254 | Grant | Trans-NIH Recovery Act Research Support: Exposure to chemical mixtures is the rule rather than the exception. Examples include diet, pharmaceutical agents and air pollution. In public health, is deemed important to develop statistical methods for estimating the toxicity of a complex mixture. By | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| NEVADA SYSTEM OF HIGHER EDUCATION | $144,000 | Grant | Trans-NIH Recovery Act Research Support: Perfluorinated hydrocarbon compounds such as perfluorooctane sulfonate (PFOS) are emerging contaminants of concern. Concentrations of PFOS have been detected in water, house dust and in human serum. PFOS is persistent, bioaccumulative, and highly toxic. C | Health and Human Services, Department of / National Institutes of Health | 11/10/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $361,940 | Grant | Trans-NIH Recovery Act Research Support: Cellular restriction of HIV infection in host cells reflects innate antiviral immunity. Monocytes are important immune sentinels and precursors of antigen presenting cells. Undifferentiated human monocytes are resistant to HIV infection despite the expres | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| SALK INSTITUTE FOR BIOLOGICAL STUDIES,THE | $4,429,620 | Grant | National Center for Research Resources, Recovery Act Construction Support: The Salk Institute for Biological Studies focuses on fundamental biomedical discoveries aimed at the improvement of human health. Led by 57 faculty members, the Salk receives ~$58 million annually from the NIH in the form of i investigator-initiated grant s... Show more | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $3,999,496 | Grant | National Center for Research Resources, Recovery Act Construction Support: Oregon Health & Science University (OHSU) seeks funds to construct new outdoor group housing and a clinic and hospital support facility at the Oregon National Primate Research Center (ONPRC). The proposed outdoor group housingng will be called the Primate E... Show more | Health and Human Services, Department of / National Institutes of Health | 10/20/2009 |
| LOS ALAMOS NATIONAL SECURITY, LLC | $730,160 | Contract | : Broadly reactive human antibodies against influenza M2 for therapy and prophylaxisG? Influenza is a globally important pathogen responsible for intermittent lethal pandemics. Present vaccination strategies are mainly based on a trivalent vaccine created p | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF LOUISVILLE | $195,360 | Grant | Trans-NIH Recovery Act Research Support: To examine the anti-tumorgenific effects of CSN disruption using genetic and pharmacologic testing of CSN5 both in vitro and in murine models of human lung cancers. Award relinquished in full on January 14, 2010. | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| KAUNITZ, JONATHAN D | $336,500 | Grant | Trans-NIH Recovery Act Research Support: The purpose is to delevop and characterize an in vitro system for measurement of dudenal bicarbonate secretion. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| XAVIER UNIVERSITY OF LOUISIANA | $341,660 | Grant | Trans-NIH Recovery Act Research Support: Research is focused on drug development against potentially blinding human eye disease herpetic stromal keratitis. During this period, I have published a patent application WO/2012/027524 A METHOD OF INHIBITING ANGIOGENESIS including the inhibition of abn | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $487,250 | Grant | Trans-NIH Recovery Act Research Support: Research to Address the Heterogeneity in Autism Spectrum Disorders (R21) Project title: An ex-vivo placental perfusion system to study materno-fetal biology. This grant will focus on developing and validating a model system to examine the effects of alter | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MAINE MEDICAL CENTER | $501,085 | Grant | Trans-NIH Recovery Act Research Support: Marrow adiposity has long been identified as a component of the bone marrow micro-environment, although its function, relevance to mineral metabolism and relationship to energy homeostasis has been ignored until recently. Adipocytes originate from a commo | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| LOS ALAMOS NATIONAL SECURITY, LLC | $443,846 | Contract | : Riboswitch design principles: interplay between switching, ligand binding and foldingG? Riboswitches are recently discovered powerful noncoding RNAs that turn on or off gene expression, depending on the presence of a ligand. We will use an approach that | Health and Human Services, Department of / National Institutes of Health | 8/30/2009 |
| MAHARISHI UNIVERSITY OF MANAGEMENT RESEARCH INSTITUTE | $998,507 | Grant | Trans-NIH Recovery Act Research Support: The broad Challenge Area is:09 Health Disparities. The specific Challenge Topic is: Develop tools to detect early indicators of health disparities, and to test collaborative interventions to reduce differential health care or outcomes of heart, lung,and | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| ABIOMED, INC. | $999,794 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research and Specific Challenge Topic 04-HL-110 Treatment of pulmonary hypertension and right heart failure. The overall objective of this proposed program is the U.S. clinical introduction of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $499,582 | Grant | Trans-NIH Recovery Act Research Support: Cholera has reemerged as a global killer with the world witnessing an unprecedented rise in cholera infection and transmission. The causative agent of cholera is Vibrio cholera, a natural inhabitant of environment but is more prevalent in coastal ecosyste | Health and Human Services, Department of / National Institutes of Health | 11/06/2009 |
| SETON HALL UNIVERSITY | $1,019,476 | Grant | Trans-NIH Recovery Act Research Support: The objective of this research is to determine if the developing dopaminergic system in the adolescent is a significant factor in the adolescent?s vulnerability to alcohol abuse and, ultimately, to developing alcohol addiction and dependence. The high ris | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $3,425,234 | Grant | Trans-NIH Recovery Act Research Support: Relapse after therapy remains a critical problem for most types of cancer in humans, even when cancer-specific therapy is initially effective. Understanding the basis for cancer resistance and recurrence is a critical pre-requisite for developing more eff | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BATTELLE MEMORIAL INSTITUTE | $985,726 | Grant | Trans-NIH Recovery Act Research Support: This is a combined submittal for 1RC2ES018786-01,3RC2ES018786-01S1, 5RC2ES018786-02 The increasing use of engineered nanomaterials in industrial and medical applications is expected to increase both unintended environmental or occupational exposures and | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION | $4,026,764 | Grant | Trans-NIH Recovery Act Research Support: This is a combined project led by the American College of Cardiology (ACCF) and The Society of Thoracic Surgeons (STS) to compare two procedures to treat coronary artery disease (CAD), percutaneous coronary intervention (PCI) and coronary artery bypass gr | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TUSKEGEE UNIVERSITY | $1,265,489 | Grant | Trans-NIH Recovery Act Research Support: Bioethics infrastructure initiative focused on bioethics training, inclusive of clinical trails, for delivery to biomedical scientists and health care professionals. | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $358,750 | Grant | Trans-NIH Recovery Act Research Support: This enables the purchase of a TRIPLE RESONANCE OBSERVE Detection Cyroprobe that will optimize the power of our Avance III 800 Nuclear Magnetic Resonance spectrometer. It will have one cryoplatform and two triple-resonance cryoprobes that are optimized | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $380,800 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to support the purchase of a Scanco CT100 specimen micro computed tomography scanner (?CT) that is to be part of an Imaging Core Facility at the University of Michigan School of Dentistry. This instrument will mainly support NIH-sponsor | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $250,000 | Grant | Trans-NIH Recovery Act Research Support: Purchase of the MicroCal AutoITC System to support NIH-funded projects from PIs across the UAB campus and Emory who require a quantitative and complete thermodynamic evaluation of the molecular interactions of biological macromolecules. | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| BROAD INSTITUTE, INC., THE | $253,795 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In this proposal six NIH-funded faculty from the Broad Institute of MIT and Harvard request to purchase a Nanostring nCounterTM Analysis System. Nanostring is a new technology for multiplex measurement of up to 550 gen | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $364,762 | Grant | Trans-NIH Recovery Act Research Support: A Biacore T100 Surface Plasmon Resonance instrument is requested. The instrument will be housed in the UTHSCSA Center for Macromolecular Interactions. It will support a wide range of projects that are supported by 7 different NIH institutes including the | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| DUKE UNIVERSITY | $446,281 | Grant | Trans-NIH Recovery Act Research Support: Caenorhabditis elegans, a multicellular roundworm of approximately 1000 differentiated cells in adult animals, offers numerous advantages, namely it has an extremely short generation time, and its genome can be readily mutagenized, so that together with r | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $315,427 | Grant | Trans-NIH Recovery Act Research Support: In this proposal, a group of six faculty members in the Division of Chemistry and Chemical Engineering at the California Institute of Technology are requesting a shared 400 MHz nuclear magnetic resonance spectrometer. All are synthetic organic chemists; | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| UNIVERSITY OF CINCINNATI | $358,323 | Grant | Trans-NIH Recovery Act Research Support: In order for structural biologists to continue to tackle increasingly difficult problems, it is vital to exploit whatever technological advances are available. The current proposal requests funds to purchase a state-of-the-art console for the 800 MHz NMR | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF NOTRE DAME DU LAC | $125,000 | Grant | Trans-NIH Recovery Act Research Support: Funds are requested to purchase a new generation, highly sensitive isothermal titration calorimeter. This instrument will replace older models currently on campus. A major benefit of the new instrument will be the requirement for smaller reaction volumes | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $323,785 | Grant | Trans-NIH Recovery Act Research Support: A fermentation system is requested, comprising a pilot scale fermentor for cell growth and a continuous flow centrifuge for cell harvest. This system will replace existing equipment that is 30 years old and lacks many capabilities of modern fermentors. Th | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| SCHEPENS EYE RESEARCH INSTITUTE, INC., THE | $332,840 | Grant | Trans-NIH Recovery Act Research Support: In this project, a multi-institutional group of investigators from the Boston area will purchase a state-of-the-art driving simulator with an integrated eye and head tracking system. This multi-user plan brings together investigators who have many years o | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $1,039,916 | Grant | Trans-NIH Recovery Act Research Support: The bio-molecular research community in the Los Angeles area is requesting NIH funding to purchase a state-of-art pulse electron paramagnetic resonance (EPR) spectrometer, the EleXsys FT-EPR system from Bruker Corporation. Pulse EPR spectroscopy is a powe | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Proteinuria is one of the most important problems in medicine today. Its presence is associated with markedly increased morbidity and mortality. The events that result in and perpetuate proteinuria are incompletely understood. The goal of this proposal is | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| THE WASHINGTON UNIVERSITY | $39,920 | Grant | Trans-NIH Recovery Act Research Support: This application is for an administrative supplement for parent grant DK064989, entitled Cellular mechanisms that promote or prevent lipotoxicity. Specifically, funds are being requested for the purchase of a quantitative real-time PCR instrument that wil | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| THE WASHINGTON UNIVERSITY | $70,000 | Grant | Trans-NIH Recovery Act Research Support: Hh signaling plays a fundamental role in both development and homeostasis of a wide variety of tissue types in mammals. The parent grant proposed three aims to investigate both the molecular mechanism underlying Ihh signaling in skeletal development, and | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $76,099 | Grant | Trans-NIH Recovery Act Research Support: Multiple potential causes of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) have been proposed, but conclusive proof of any specific cause remains elusive. However, many patients report one or more episodes of bladder infection prior to the onset | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $99,960 | Grant | Trans-NIH Recovery Act Research Support: The kidney collecting system arises through branching morphogenesis of the ureteric bud (UB), a process that we have been able to replicate in vitro by culturing the isolated UB in the presence of a metanephric mesenchyme cell conditioned medium. Our puri | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $30,000 | Grant | Trans-NIH Recovery Act Research Support: We are requesting a supplement to the parent grant to purchase of equipment necessary to allow us to quantify mRNA in our oligodendrocyte cell cultures. We will initially measure mRNA of proteins known to be induced in oligodendrocytes by diabetes that | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $88,898 | Grant | Trans-NIH Recovery Act Research Support: This application is submitted in response to NOT -OO-09-056NIH Announces the Availability of Recovery Funds for Administrative supplements. During the first 5 years of support for OK 57878 -Effect of insulin on the microvasculature, we investigated the | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $99,547 | Grant | Trans-NIH Recovery Act Research Support: Growth hormone (GH) regulates postnatal growth and metabolism in vertebrates in an endocrine fashion. In addition, recent studies suggest roles for autocrine-derived GH and for an intact GH axis in formation and behavior of cancers in animals. GH receptor | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $53,636 | Grant | Trans-NIH Recovery Act Research Support: The supplement funding to 2 RO1 DK058702-06 A2, entitled !Episomal lenti vector for a humanized hemophilia mouse!, will enable us to hire/retain three researchers whose additional skills and research capabilities would significantly expedite our progress | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The adipoeyte-secreted hormone leptin signals the amount of energy stored in adipose tissue to the central nervous system. We have shown, in the context of this grant, that leptin administration to normalize the relative leptin deficiency induced by short | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| MONELL CHEMICAL SENSES CENTER | $30,000 | Grant | Trans-NIH Recovery Act Research Support: In mice, many genomic regions contain variation that results in differences in adiposity (Reed 2003; 2006; 2007; 2008). The goal of this research program is to find the gene or genes on mouse chromosome 9 that account for the quantitative trait locus Adip | Health and Human Services, Department of / National Institutes of Health | 11/16/2009 |
| PURDUE UNIVERSITY | $98,899 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION: In the elderly, gastrointestinal (GI) disorders are common, often either complicate or are complicated by other diseases, and can be debilitating. Research over the last decade has established that aging-related GI disorders are correlated wi | Health and Human Services, Department of / National Institutes of Health | 1/04/2010 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $99,916 | Grant | Trans-NIH Recovery Act Research Support: Obesity is a prevalent and serious metabolic disease, and is the most significant risk factor for type 2 diabetes and cardiovascular and cerebrovascular diseases. The major goal of this work is trying to better understanding how the central melanocortin | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $99,921 | Grant | Trans-NIH Recovery Act Research Support: The unique property of polycystin-1 (large size, transmembrane nature and low level of expression of the protein) makes the analyses of the protein a great challenge. The proposed biochemical characterization of the complex polycystin-1 products using the | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| YALE UNIVERSITY | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The short-term deleterious effects of acute kidney injury (AKI) on morbidity and mortality are well-known from several epidemiological studies. However, the long-term sequelae of AKI have not been thoroughly explored. Although AKI has been widely consider | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| LONG ISLAND UNIVERSITY | $125,720 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will be used to support a community health educator (CHE) for outreach, education, coordination and evaluation. This individual's primary responsibility will be to adapt cancer education materials, including those from nati | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $540,706 | Grant | Trans-NIH Recovery Act Research Support: Generation of functionally competent B lymphocytes is essential for producing antibodies (also called immunoglobulin, B cell receptor), the molecules mediating body's humoral immunity against pathogens and tumor cells. Abnormal B cell function and develop | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| YALE UNIVERSITY | $39,541 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the proposed study is to investigate the role of cholesterol, including serum and islet cholesterol, in pancreatic (-cell dysfunction that characterizes the progression of type 2 diabetes. Alteration of pancreatic (-cell function leadi | Health and Human Services, Department of / National Institutes of Health | 12/26/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $80,204 | Grant | Trans-NIH Recovery Act Research Support: Accelerate the in vitro experiments of Specific Aim III. Use microarray techniques to analyze mRNA expression by freshly isolated TLR4 sufficient versus deficient endothelia and tubules from ischemic kidneys. | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $97,508 | Grant | Trans-NIH Recovery Act Research Support: Obesity is now recognized as a chronic inflammatory state due in large part to the infiltration into fat of immune cells called macrophages. This infiltration of macrophages is associated with fat inflammation and insulin resistance. Studies proposed in | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $67,063 | Grant | Trans-NIH Recovery Act Research Support: The primary purpose of this supplement funding request is to evaluate renal blood flow and measure GFR in mice subjected to the cecal ligation and puncture (CLP) model of sepsis. Our studies during year 1 revealed that systemic blood pressure might be pla | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $92,437 | Grant | Trans-NIH Recovery Act Research Support: Title: NBC1 and Proximal RTA Pathogenesis and Treatment Description: Mutations in the SLC4A4 gene encoding the electrogenic sodium bicarbonate cotransporter NBC1 (NBCe1-A) cause hereditary proximal renal tubular acidosis (proximal RTA). Various mutations | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| BOSTON MEDICAL CENTER CORPORATION | $91,249 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this project is to define the role of ROBO2 deficiency in the pathogenesis of vesicoureteral reflux (VUR) and reflux nephropathy. VUR is one of the commonest genetic disorders found in children, with an incidence of about 1:100. | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $63,990 | Grant | Trans-NIH Recovery Act Research Support: The supplement request is a direct continuation of the parent grant. It follows the same idea and strategy, but deepens the approach by studying trafficking of endonucleases by using state-of-the-art equipment. The hypothesis of the overall project is tha | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Regulation of PTH-Induced Osteoanabolism by Inflammatory Lipids: The Aim of the parent grant is to determine the inhibitory mechanism of high cholesterol levels, hyperlipidemia, on bone repair and on the efficacy of parathyroid hormone (PTH) treatment of | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $59,390 | Grant | Trans-NIH Recovery Act Research Support: The parent project deals with understanding how cellular metabolism is modified in a situation of nutritional copper deficiency using Chlamydomonas as a reference organism. Our goal was to understand the mechanism of copper sensing via regulator named CRR | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The parent grant, which is in its 19th year of funding, seeks to understand the mechanisms by which long-range repressors direct the formation of large transcriptionally silent chromosomal domains. In particular, we are focusing on the corepressor Groucho | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $195,378 | Grant | Trans-NIH Recovery Act Research Support: Phage lambda Integrase (Int) is the prototype of a large family of tyrosine recombinases that performs site-specific recombination. The family includes bacterial, phage, conjugative transposon, integron and yeast plasmid enzymes. Many of these elements co | Health and Human Services, Department of / National Institutes of Health | 12/11/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $148,432 | Grant | Trans-NIH Recovery Act Research Support: The essential contribution of the secreted Hedgehog signaling molecules to embryonic development and tissue homeostasis in post-embryonic animals is well established. Frequently misactivation of the Hh signal transduction pathway results in cancer. The | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $74,535 | Grant | Trans-NIH Recovery Act Research Support: The specific aim of this Administrative Supplement is to enhance overall program development and accelerate the implementation of activities and achievement of stated goals through the development of a new partnership, the expansion of current personnel p | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $199,852 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of this proposal revolve around the need to understand how this multifunctional pathway performs funtctions that are ligand specific at selected sites of action. We know a great deal about this pathway, but not nearly enough to underst | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $65,023 | Grant | Trans-NIH Recovery Act Research Support: Molecular chaperones are involved in a wide range of essential cellular processes: protein synthesis, molecular assembly, translocation, degradation, and folding. The E. coli molecular chaperone GroEL, along with its cochaperone GroES, increases the effic | Health and Human Services, Department of / National Institutes of Health | 12/24/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $90,656 | Grant | Trans-NIH Recovery Act Research Support: We study the molecular mechanisms controlling gradient formation by morphogens, signaling molecules that specify different cell fates at distinct concentration and signaling thresholds. These molecules provide a fundamental mechanism of generating patter | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $43,798 | Grant | Trans-NIH Recovery Act Research Support: Translation termination is the final stage of protein synthesis. It includes at least two essential functions, stop codon recognition and polypeptide chain release. In eukaryotic organisms, the class I release factor eRF1 recognizes each of the three term | Health and Human Services, Department of / National Institutes of Health | 12/25/2009 |
| UNIVERSITY OF WASHINGTON | $20,804 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to further develop Methanococcus maripaludis as a model organism. Work to date under this grant as well as work preceding this grant have led to the development of outstanding tools, which we propose to augment. As a member o | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| BENEDICT COLLEGE, THE | $78,904 | Grant | Trans-NIH Recovery Act Research Support: The MBRS-RISE Program supported student research and development. | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. | $117,948 | Grant | Trans-NIH Recovery Act Research Support: The goals of the RISE at Universidad Metropolitana (UMET) program are: (1) to increase the number of Puerto Rican students engaging in biomedical and behavioral research, and (2) to motivate a larger number of students in the School of Science and Technol | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $600,000 | Grant | Trans-NIH Recovery Act Research Support: Bronx Community Research Review Board: Evaluation of an Innovation Model for Community-based Research Consultation & Review (Date of award: 9/3/09) Aim 1. With the Bronx Health Link collaboratively develop an independent Bronx Community Research Review | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $98,925 | Grant | Trans-NIH Recovery Act Research Support: Produce and purify the modified tRNA reagent utilized to identify novel protein interactions with CFTR as outlined in Aim 3 of the parent Grant. | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $1,701,287 | Grant | Trans-NIH Recovery Act Research Support: The funds will be used to develop, open and analyze three H1N1 studies in HIV-infected populations. The first study will determine the safety and immunogenicity of an H1N1 vaccine in HIV-infected pregnant women. The second study will determine safety an | Health and Human Services, Department of / National Institutes of Health | 11/25/2009 |
| UNIVERSITY OF PUERTO RICO | $246,820 | Grant | Trans-NIH Recovery Act Research Support: To provide support for initiatives funded under The American Recovery and Reinvestment Act of 2009 (ARRA). This project will provide economic stimulus to the nation while furthering the NIH mission to uncover next knowledge that will lead to better healt | Health and Human Services, Department of / National Institutes of Health | 11/15/2009 |
| MOREHOUSE COLLEGE (INC.) | $84,928 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the MBRS-SCORE program is to increase the capacity of faculty research in order to enhance student education. This is consistent with the mission of Morehouse College. Faculty research capacity will be enhanced by the addition of stat | Health and Human Services, Department of / National Institutes of Health | 9/12/2009 |
| SOUTHERN UNIVERSITY SYSTEM | $144,570 | Contract | : Southern University at Baton Rouge (SUBR) proposes to re-establish the MBRS-SCORE program on its campus. The overall long-term goal of the proposed program is to enhance and expand the overall biomedical research capability of the university. Goal 1 is de | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $69,206 | Grant | Trans-NIH Recovery Act Research Support: Individual investigator-initiated research projects for faculty at MSIs to conduct research of limited scope in environments with limited research infrastructure/facilities. | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $95,000 | Grant | Trans-NIH Recovery Act Research Support: The NLM-sponsored Biomedical Informatics (BIT) Training Program of the University of California, Irvine is administered by the UCI Institute for Genomics and Bioinformatics (IGB). The BIT Program recruits predoctoral students and postdoctoral fellows from | Health and Human Services, Department of / National Institutes of Health | 12/24/2009 |
| NATIONAL COALITION OF ETHNIC MINORITY NURSE ASSOCIATIONS, INC. | $151,746 | Grant | Trans-NIH Recovery Act Research Support: Nurse Scientist Stimulation Program works to increase the number of ethnic minority nurse researchers (PhD) by addressig four specific aims: 1) creating a network of ethnic minority nurse researchers, 2) developing the mechanisms to support and engage eth | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $530,618 | Grant | Trans-NIH Recovery Act Research Support: This supplement supports the IMPAACT Statistical and Data Management Center in the design, data analysis and presentation of results from 3 IMPAACT studies of the safety and immunogenicity of H1N1 influenza vaccines in HIV-infected children, youth, and pr | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| AMERICAN SAMOA MEDICAL CENTER AUTHORITY | $111,068 | Grant | Trans-NIH Recovery Act Research Support: Research Project Cooperative Agreement from the Natl. Cancer Institute to the American Samoa Community Cancer Network (N.C.I. grant funded project - award #U01CA114590) to support the 'Patient Navigators for the Cancer Care Continuum' ARRA Program. | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Prevention Program Outcomes Study (DPPOS) Diabetes Prevention Program (DPP) demonstrated that lifestyle and metformin reduce the risk of diabetes (DM) by 58% and 31% (NEJM 346;393-403,2002). The DPPOS, now in year 7, aims to determine whether re | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $46,617 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Prevention Program Outcomes Study (DPPOS) The supplement's purpose is to provide new computers for data entry to the 26 DPPOS clinical centers. The Diabetes Prevention Program (DPP) demonstrated that lifestyle and metformin reduce the risk of di | Health and Human Services, Department of / National Institutes of Health | 12/23/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Equipment used in relation to work being carried out on parent grant (1DP2DK083052-01). The overall goal of our work is to develop a means for preventing type I diabetes (T1D) by inducing tolerance to the auto-antigens involved in the pathogenesis of the | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $154,288 | Grant | Trans-NIH Recovery Act Research Support: Our requests for supplemental funding will allow us to accelerate our progress in several areas, and each of these requests are driven by technological advances in parallel with an enhanced understanding of the increasingly complex signaling networks that | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF CHICAGO, THE | $75,622 | Grant | Trans-NIH Recovery Act Research Support: Our research involves specific aims distributed among three projects served by three cores. Of these, some are currently in progress as a result of new findings discovered during the present grant period. The remainder represent new projects. Almost all o | Health and Human Services, Department of / National Institutes of Health | 11/26/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $144,830 | Grant | Trans-NIH Recovery Act Research Support: This Supplemental requests funding to improve our ability to isotopically label peptides and proteins by creating a new research position and by purchasing equipment for this purpose. These steps will accelerate our research and in the process of doing so | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $105,792 | Grant | Trans-NIH Recovery Act Research Support: Chronic renal insufficiency (CRI) is a G??silent epidemicG?? affecting an estimated 10 million Americans. CRI progresses at an unpredictable rate to end stage renal disease (ESRD) with the associated high morbidity, mortality and costs. The Chronic Renal | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $80,751 | Grant | Trans-NIH Recovery Act Research Support: PROJECT NARRATIVE Obesity, sequelae of which include diabetes mellitus and cardiovascular disease, is a major public health challenge. A better understanding of the molecular physiology of energy balance is critical to the development of effective therape | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF MARYLAND | $40,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetes mellitus in pregnancy is one of the maternal diseases that cause congenital defects in infants. Although control of glycemic level during pregnancy has been associated with reduced rate of malformed infants, nevertheless, achieving and maintainin | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $97,802 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): In the brain, key focal points for control of metabolic function and feeding behavior are melanocortin receptors MC3R and MC4R. These receptors respond to two ligands, alpha-melanocyte stimulating hormone and Agouti-re | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $193,370 | Grant | Trans-NIH Recovery Act Research Support: This supplemental project is focused on accelerating and enhancing the tempo and productivity of the parent project developing new hyperpolarized metabolic imaging methods by funding a new post-doctoral position. This post-doctoral fellow will develop spe | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| PARION SCIENCES, INC | $500,000 | Grant | Trans-NIH Recovery Act Research Support: We are developing a therapeutic countermeasure for radiological material inhalation exposure through the product development process. As discussed below, the greatest risk to the lungs following a radiological attack, such as a dirty bomb, results from th | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $4,753,886 | Grant | Trans-NIH Recovery Act Research Support: The genetic components of age-related disorders are of intense interest, and genome wide association studies (GWAS) are an important tool in identifying chromosomal loci that are associated with disease. Two of the major and interlinked challenges for suc | Health and Human Services, Department of / National Institutes of Health | 11/25/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $90,000 | Grant | Trans-NIH Recovery Act Research Support: Immunology T lymphocytes are central mediators of adaptive immunity, playing a key role in both appropriate immune responses (such as immunity against pathogens) and abnormal ones (such as autoimmune response that lead to type 1 diabetes). Optimal activat | Health and Human Services, Department of / National Institutes of Health | 12/19/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $85,000 | Grant | Trans-NIH Recovery Act Research Support: One to two million people in the United States suffer from type 1 diabetes mellitus. Diabetic cardiomyopathy is an impairment of heart muscle that exists independently of coronary artery disease, and is associated with diabetes mellitus Diabetic cardiom | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $67,087 | Grant | Trans-NIH Recovery Act Research Support: The intended impact of the research is to establish a platform for preclinical testing of peptides and small molecules that promote the formation of new beta cells from ducts. Such an approach could, if ultimately successful, significantly lower the barri | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: CooleyG??s anemia or beta-thalassemia major is a severe congenital anemia caused by deficient production of the beta chain of hemoglobin (Hb) and characterized by ineffective erythropoiesis and hemolysis. Current disease management consists of prenatal di | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF WASHINGTON | $12,496 | Grant | Trans-NIH Recovery Act Research Support: Transforming growth factor TGF-Beta is required for early protective responses to injury and infection; yet, when dysregulated its activity persists thereby leading to organ scarring and clinical disease. We previously showed that Smad3 is required for T | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Autosomal dominant polycystic kidney disease (ADPKD) is the most common life threatening hereditary renal disease. ADPKD is characterized by progressive development and enlargement of cysts in ADPKD kidneys. These enlarging cysts continuously compre | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| UNIVERSITY OF MIAMI | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Beta2 integrins are critical for the normal function of leukocytes. Yet, the structural mechanism behind integrin activation is not completely clear. The overall goal of this project is to define structural mechanisms behind integrin activation. | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The parent K01 award of this supplement aimed to study role of ADAMs ( a disintegrin and metalloenzymes) in cross-talk between G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that are present in physiological condition in renal me | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Megakaryopoiesis is a complex process by which bone marrow cells called megakaryocytes (MK) give rise to circulating platelets. Normal platelet production depends on two unique events that characterize megakaryopoiesis: polyploidization and proplatelet fo | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF WASHINGTON | $51,398 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement application is to speed up the tempo of investigating the hematopoietic/erythroid differentiation of human embryonic stem cells. In Specific Aim 1, we will be studying the effect of HoxB4 on improving the hematop | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| MAINE MEDICAL CENTER | $54,000 | Grant | Trans-NIH Recovery Act Research Support: G?Role of Slug in Regulation of Hematopoietic Stem CellsG? Although retaining enormous proliferative capacity, most hematopoietic stem cells (HSCs) reside in a state of relative quiescence in vivo under homeostatic conditions, with a cell division cycle o | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| THE WASHINGTON UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In this application for administrative supplemental funding to grant K01DK078318, no new specific aims are proposed. Instead, we propose a set of expenditures that will greatly accelerate the pace of completion of aims 1d and 3a already described in the | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| UNIVERSITY OF PITTSBURGH THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to characterize the binding of a relatively new inhibitor of the epithelial sodium channel (ENaC). ENaC helps facilitate Na+ transport across epithelia in the kidney where it helps regulate extracellular Na+ balance and blood pre | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Aim of the study was to examine the magnitude of importance and age related changes in voltage-dependent calcium channel (VDCC) CaV2.1 (L-type) and CaV2.3 (R-type) subunits in the rat urinary bladder. a) Expression and distribution of anti- CaV2.1 and an | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $53,520 | Grant | Trans-NIH Recovery Act Research Support: A 5-year plan is proposed in which the candidate will establish herself as an independent investigator in Stem Cell biology and further our understanding of hematopoietic stem cells generated by embryonic stem cells (ESC-HSC). In graduate school, the cand | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| EMORY UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The parent grant, 1K01DK082733-01, aimed to determine if a vasopressin-mediated increase in intracellular cAMP would stimulate a specific signaling complex of proteins that regulate UT-A1 function. The above hypothesis will be resolved by: 1. Determining | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $103,661 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to provide additional time for establishing grant-writing skills and new collaborative efforts in international health while further building a research base in Afghanistan. For this reporting period, 134 female follow-u | Health and Human Services, Department of / National Institutes of Health | 11/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $53,200 | Grant | Trans-NIH Recovery Act Research Support: The objective of this supplement is to support expanded device development within the scope of Dr Weitzel's K08 award novel methods of hemodialysis evaluation. Dr Weitzel's K08 award has two main objectives: 1) Develop and test a prototype Doppler device | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF IOWA, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The Pax2 gene is an essential regulator of early renal development and has also been implicated in a variety of human diseases both congenital and acquired. During embryonic development, Pax2 is required for the initiation and maintenance of the conversio | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF ROCHESTER | $49,538 | Grant | Trans-NIH Recovery Act Research Support: Recently, an autosomal recessive K+ wasting syndrome (SeSAME/EAST syndrome) was reported in several families which linked to the Kir4.1 gene locus (KCNJ10).-?-?-? Six Kir4.1 mutations were reported.-? The patients had seizures, deafness, and ataxia along | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $54,000 | Grant | Trans-NIH Recovery Act Research Support: In the setting of end-stage bladder disease, current bladder replacement techniques involve the use of intestinal segments, which are associated with significant perioperative morbidity and long-term complications. Combining tissue engineering techniques | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $53,378 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes a 5 year training program for the continued development of a career in academic nephrology. The principal investigator has completed residency and clinical nephrology training in Boston and now will expand his scientific skills thr | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| DUKE UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Uropathogenic Escherichia coli (UPEC) is by far the leading cause of urinary tract infection (UTI), producing 8 of the 10 million infections in the US per year. The most serious complications of UTI include pyelonephritis, sepsis, and meningitis. However, | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the parent grant that will benefit from the Administrative Supplement is to define the role of renin during the differentiation of ectodermal precursors into their derivative tissues (Le. skin., choroid plexus, sympathetic ganglia, adren | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The applicant proposes a program to prepare for a career in academic medicine and basic science research in the field of TGF-beta superfamily signaling and iron metabolism. Research will be conducted in the laboratory of Dr. Dennis Brown at MGH. Iron home | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $54,000 | Grant | Trans-NIH Recovery Act Research Support: As a pediatric hematologist, I feel a great need to understand the mechanisms behind the dysregulation of differentiation and proliferation that occur in certain acquired and congenital aplastic anemias and leukemias found in my patient population. The mo | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Diabetic nephropathy, the leading cause of renal failure in the United States, results from injury to the renal microvasculature. In this proposal, we use rodent models to investigate the protective role of ENTPD1 (also known as CD39) in renovascular dise | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $38,058 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Growing evidence suggests that inflammation may be a central mechanism behind the development of many obesity-related diseases that include the metabolic syndrome and diabetes. Inflammatory changes in obesity include t | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $52,599 | Grant | Trans-NIH Recovery Act Research Support: Kidney transplantation is an obvious candidate for value based purchasing initiatives, aimed at improving quality and reducing costs of kidney transplant care in the United States. There is wide variation in quality, a large, single payer (CMS), and high | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Tile parent grant of this proposal, Adenosine A2a Receptor Agonist in Diabetic Nephropathy, was designed to study the anti-inflammatory, hemodynamic and antiproteinuric effects of A2a agonist in individuals with type 2 diabetes and nephropathy as compare | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $50,288 | Grant | Trans-NIH Recovery Act Research Support: This comprehensive five-year career development plan has a two-fold purpose: 1) to bring about the candidate's development into an independent clinical investigator through a combination of formal didactic coursework, directed mentoring and the conduct of | Health and Human Services, Department of / National Institutes of Health | 1/08/2010 |
| TRUSTEES OF INDIANA UNIVERSITY | $49,917 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to support a research coordinator that will assist Dr. MoeG??s mentees in clinical research projects that involve dialysis patients. These projects are broadly in the field of musculoskeletal diseases of di | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $53,826 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will enhance the activities and aims approved by the parent grant (5 K24 DK068389). It will allow us to continue research initiatives, as well as the clinical care offered through the UAB Genitorectal Disorders clinic. The a | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $53,040 | Grant | Trans-NIH Recovery Act Research Support: My educational background is in physics (B. S. and M.S.) and materials engineering (PhD). My academic research over the last five years has been focused on both ballistic electron transport and microfluidics. I built a microfabricated microfluidic sensor | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $48,535 | Grant | Trans-NIH Recovery Act Research Support: Craniofacial and dental genetic disorders like CL/P constitute a significant public health burden. The parent grant focuses on enhancing our understanding of such complex traits by developing, implementing computationally, and applying in analyses, statis | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF PITTSBURGH THE | $51,109 | Grant | Trans-NIH Recovery Act Research Support: The award is to accelerate data acquisition related to the activities of the K99 award listed above. To this end, new equipment will be purchased to triple the available electrophysiological equipment from 3 to 9 chambers to accelerate the pace of researc | Health and Human Services, Department of / National Institutes of Health | 12/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $30,739 | Grant | Trans-NIH Recovery Act Research Support: This is a request for supplementary funds to the parent grant DK080981, Stress-Induced Bladder Hyperalgesia: A Potential Mediator, to procure a FluoSTAR microplate reader ($30,000.00; BMG Labtech, Durham, NC.) and a Dell computer ($640.00) and printer ($9 | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $157,183 | Grant | Trans-NIH Recovery Act Research Support: This award has allowed us to purchase much needed equipment to allow us to study bone development. These studies form the basis for our discovering novel treatments for osteoporosis. | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| SALK INSTITUTE FOR BIOLOGICAL STUDIES | $129,680 | Grant | Trans-NIH Recovery Act Research Support: The parent grant focuses on the role of the CRF family peptides, their cognate receptors, and CRF-binding protein on the modulation of endocrine responses to challenge. This work has identified Ucn 2 as a paracrine inhibitor of insulin-induced skeletal m | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF PITTSBURGH THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The equipment we have requested constitutes the essential components of a rig enabling the physiological and pharmacological analysis of isolated cells. At the core of this set-up is an inverted microscope that enables visualization of the cells of intere | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $246,095 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement for grant entailing studies aimed at understanding the cellular and molecular basis for diabetes and related metabolic diseases. Funds are requested to supplement 2 projects and 2 cores and will lead to 1) the creation | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| DUKE UNIVERSITY | $28,960 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of our NIH-funded program project PO1DK58398-9, now in its ninth year, has been to develop new therapies for type 2 diabetes by melding of novel insights into b-cell biology with unique metabolic analysis, imaging, and molecular manip | Health and Human Services, Department of / National Institutes of Health | 12/09/2009 |
| BAYLOR COLLEGE OF MEDICINE | $110,110 | Grant | Trans-NIH Recovery Act Research Support: Purchase of Biospectrum 600 Imaging System, Stepone Plus RT PCR System and Thermo Nanodrop Spectrophotometer | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $267,501 | Grant | Trans-NIH Recovery Act Research Support: A complex interaction of different processes play a critical role in the development of hematopoietic lineages, and among the most important are the controls of hematopoietic stem cell (HSC) commitment. Understanding this process is critical to understand | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This award of $100,000 was for partial funding for a Bruker Biospin 800 MHz solution NMR spectrometer costing $1,050,000. The spectrometer dramatically enhance access to high-field NMR spectrometer time urgently needed for studies of large proteins and pr | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MCLAUGHLIN RESEARCH INSTITUTE FOR BIOMEDICAL SCIENCES, INC. | $137,568 | Grant | Trans-NIH Recovery Act Research Support: Genetics of Prion Susceptibility in Vitro The overall goal of the parent project is to understand genetic susceptibility to prion disease and to identify pathways involved in the conversion of normal, benign prion protein (PrPC) to the malignant disease- | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| LINCOLN UNIVERSITY | $343,215 | Contract | : The overall purpose of GMaP is to create state-of-the-art regional networks or centers dedicated to cancer health disparities research and care. This award covers Area 5, which includes Massachusetts, Michigan, Minnesota, New York, Ohio, and Pennsylvania | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF THE VIRGIN ISLANDS | $600,000 | Grant | Trans-NIH Recovery Act Research Support: The grant's objectives support the mission of the NCMHD and the UVI Caribbean Exploratory Research Center's aim to enable academic,institutional and community partners to evaluate interventions designed to improve the health of Virgin Islanders. The proje | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF WASHINGTON | $273,452 | Grant | Trans-NIH Recovery Act Research Support: The University of Washington Diabetes Endocrinology Research Center (DERC) requests an administrative supplement of $1,084,523 to provide additional funds for three P&F projects and equipment for two biomedical research cores. The Specific Aims of this pr | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $318,667 | Grant | Trans-NIH Recovery Act Research Support: The Penn Diabetes and Endocrinology Research Center (DERC) participates in the nationwide interdisciplinary program established nearly three decades ago by the NIDDK to foster research and training in the areas of diabetes and related endocrine and metabo | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $231,750 | Grant | Trans-NIH Recovery Act Research Support: The overall mission of the UCLA-UCSD DERC is to foster research in the prevention and treatment of diabetes and its complications and ultimately to improve the lives of patients with diabetes. This unique Center crossed institutional boundaries to harness | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| NEW ENGLAND BIOLABS, INC. | $250,000 | Grant | Trans-NIH Recovery Act Research Support: Supplement to 3P41LM005800-14S1 maintenance of REBASE, the database of restriction enzymes and DNA methyltransferases. This supplement supports one programmer to initiate and implement new software to allow greatly increased automation during the maintena | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BATTELLE MEMORIAL INSTITUTE | $2,000,000 | Grant | Trans-NIH Recovery Act Research Support: Award Title: A Proteomics Research Resource for Integrative Biology Award Purpose: The next generation proteomics platforms will provide the tools necessary for future applications of proteomics to investigate large human populations. The data from th | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $461,220 | Grant | Trans-NIH Recovery Act Research Support: Polycystic kidney disease (PKD) is characterized by the formation of innumerous fluid-filled cysts that can expand to several centimeters in diameter due to aberrant cell proliferation. The insistent enlargement of cysts disrupts the normal renal archite | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| MAYO CLINIC | $64,209 | Grant | Trans-NIH Recovery Act Research Support: Recent studies highlight the importance of early precursor lesions in the pathogenesis of NL, a common disease affecting up to 10% of the population. Randall's plaques, first described in the 1930s, are medullary interstitial deposits of calcium phosphate | Health and Human Services, Department of / National Institutes of Health | 11/24/2009 |
| MAYO CLINIC | $181,320 | Grant | Trans-NIH Recovery Act Research Support: A robust Pilot and Feasibility Program will be an integral portion of the Mayo Clinic Urology O'Brien Center. The Center currently funds 2 projects at all times. The primary focus is to support new investigators interested nephrolithiasis (NL) research. T | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $412,532 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this program is to foster biomedical research in diabetesrelated areas and to promote the translation of research findings into improved health outcomes, especially in underserved and minority populations. Funding in this application is to | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $309,000 | Grant | Trans-NIH Recovery Act Research Support: Michigan Diabetes Research and Training Center The Michigan Diabetes Research and Training Center (MDRTC) is a multidisciplinary unit of The University of Michigan Health System. The MDRTC is now in its thirtieth year, having been funded by the NIH/NIDDK | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| THE WASHINGTON UNIVERSITY | $304,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to NIDDK RFA-DK-06-014 and is entitled Washington University Diabetes Research and Training Center (WU DRTC). The overall goal is to support centralized resources, facilities, and expertise shared by diabetes investigators at | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| THE VANDERBILT UNIVERSITY | $310,000 | Grant | Trans-NIH Recovery Act Research Support: This application from the Vanderbilt Diabetes Research and Training Center (DRTC; P60 DK020593) seeks supplemental funding under the American Recovery and Reinvestment Act of 2009 for the DRTCG??s long-standing efforts to facilitate the discovery, applica | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $99,945 | Grant | Trans-NIH Recovery Act Research Support: As the prevalence of Diabetes Mellitus increases, the need for recognizing the major cellular and molecular processes that underlie progression of the disease becomes more urgent. It is becoming increasingly clear that in patients with type 2 diabetes, P- | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Provides the funds for the procurement of additional equipment which will increase the speed at which the parent grant's specific aims are addressed. DK078732 addresses the critical need to increase the availability of pancreatic islets by pursuing the fo | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $32,287 | Grant | Trans-NIH Recovery Act Research Support: Regulation of GLUT4 Exocytosis | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $71,000 | Grant | Trans-NIH Recovery Act Research Support: Hyperglycemia and insulin resistance are two major hallmarks of type 2 diabetes. Insulin resistance can cause dysregulation of hepatic gluconeogenesis that leads to the elevated blood glucose levels in diabetics. Pyruvate dehydrogenase kinase 4 (PDK4) pro | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| JOSLIN DIABETES CENTER, INC. | $105,287 | Grant | Trans-NIH Recovery Act Research Support: Embryonic Gene Expression During Diabetic Embryopathy - The overall goal of the parent grant, G?Embryonic Gene Expression During Diabetic EmbryopathyG?, is to understand how excess glucose metabolism by embryos of diabetic mothers inhibits expression of P | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| JOSLIN DIABETES CENTER, INC. | $38,145 | Grant | Trans-NIH Recovery Act Research Support: Role of BMPs in Adipogenesis, Mitochondrial Function and Energy Homeostasis - Obesity is an epidemic health problem in the United States and worldwide that impacts the risk and prognosis of many diseases, especially type 2 diabetes mellitus, cardiovascula | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| JOSLIN DIABETES CENTER, INC. | $99,183 | Grant | Trans-NIH Recovery Act Research Support: Development Genes and the Origin of Fat. The development of obesity depends in part on the balance between food intake and energy utilization; but also on the balance between white adipose tissue, which is the primary site of energy storage, and brown ad | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $20,629 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Relevance: Alcohol and other drug use are common among U.S. adolescents. Our prior studies found that adolescents with alcohol use disorders (AUD) show abnormalities on indices .of brain functioning, including neuropsy | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $581,511 | Grant | Trans-NIH Recovery Act Research Support: Critical issues for improving the treatment of alcoholism are what neurobiological changes are responsible for the transition from non-dependent alcohol use to alcoholism, and what persistent changes mediate relapse. The goals of the present proposal are | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $4,609,171 | Grant | Trans-NIH Recovery Act Research Support: We will conduct a genome-wide scan on an Illumina 610k platform for colorectal cancer in the following well characterized study populations: The Women's Health Initiative (WHI), the Nurses' Health Study (NHS), the Physician's Health Study, (PHS), and the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $427,626 | Grant | Trans-NIH Recovery Act Research Support: This activity extends the scope of CA079992, moving to studies of the intracellular domain specifically the ErbB3 kinase domain. The proposal is to test the physiological importance of kinase activity by this domain. Central to the proposal is recruit | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $95,184 | Grant | Trans-NIH Recovery Act Research Support: Glucose toxicity accounts for insulin resistance in patients with uncontrolled type 1 diabetes and contributes to to it in type 2 diabetes. It contributes to vascular complications, the major causes of morbidity and mortality in diabetic patients. Susta | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| THE VANDERBILT UNIVERSITY | $239,408 | Grant | Trans-NIH Recovery Act Research Support: The parent grant (DK018243-34 G?Gluconeogenesis and Glycogenolysis: Role and RegulationG?) supports work carried out in the conscious dog, the specific aims of which relate to brain insulin action, hypoglycemic counterregulation and the interplay between | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $99,000 | Grant | Trans-NIH Recovery Act Research Support: Acquisition of an extracellular flux analyzer to enhance the specific aims of the parent grant studying the deleterious effects of various lipotoxicty, glucotoxicity, and other metabolic problems of Type 2 diabetes patients. | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF MASSACHUSETTS | $198,312 | Grant | Trans-NIH Recovery Act Research Support: Insulin Signaling and Metabolic Regulation in Adipocytes:Failure of normal adipocyte function has been proposed to be a key element in the development of insulin resistance and type 2 diabetes related to obesity. We have pursued studies of regulators of a | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of the proposed work are to obtain data that will allow descriptions at the molecular level how the terminal two heme synthetic pathway enzymes, protoporphyrinogen oxidase (PRO) and ferrochelatase function. The goals of the current propo | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| UNIVERSITY OF ARIZONA | $29,925 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is designed to support experiments that define the hormonal communication between bone (osteoblasts) and kidney (proximal tubule cells) which is hypothesized to regulate blood phosphate and control ectopic calcification. We | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $95,855 | Grant | Trans-NIH Recovery Act Research Support: Administration Supplement funds are requested for the purchase of laboratory equipment to support our research under grant DK33765, Cytochrome P450-Endogenous Substrate Metabolism. The supplemental funding requested will be used to purchase several pieces | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $85,238 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Ischemic and toxic acute renal failure remain important causes of morbidity and mortality in hospitalized patients and greatly increase the expense of care. ATP production in the kidney proximal tubule, a major site of | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| UNIVERSITY OF MASSACHUSETTS | $162,366 | Grant | Trans-NIH Recovery Act Research Support: The overall scope of the parent grant is to understand how ATP allosterically inhibits the transport activity of the human, blood brain barrier glucose transport protein, GLUT1 .The supplement seeks additional support to identify sites of interaction bet | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $67,291 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to upgrade antequated image analysis equipment, obtain equipment to facilitate stereotaxic surgery of the brain particularly in mice, and purchase a portable autoclave to accelorate throughput for in situ hybridization histoch | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| THE VANDERBILT UNIVERSITY | $83,241 | Grant | Trans-NIH Recovery Act Research Support: Prostaglandin E2 (PGE2) regulates blood pressure, where it can exert either vasopressor or vasodepressor effects. These physiologically opposing effects can be explained in part by the existence of four PGE2 receptors, designated the E-Prostanoid (EP) rec | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $82,388 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this project is to determine the role of the sorting proteins PACS-1 and PACS-2 in autosomal dominant polycystic kidney disease (ADPKD). This inherited disorder manifests in formation of numerous cysts in the kidney, culminating in e | Health and Human Services, Department of / National Institutes of Health | 12/29/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $35,077 | Grant | Trans-NIH Recovery Act Research Support: The broad mandate of this proposal is to use transgenic, molecular and biochemical approaches to determine the in\ vivo biological effects specific to the Pit-IB isoform with regards to Pit-1-dependent pituitary cell ontogeny and gene expression, and to d | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $74,070 | Grant | Trans-NIH Recovery Act Research Support: The proposal is for an administrative supplement to R01 DK-038765 (PI: Garvey) entitled Mechanisms of Human Resistance. This program has been continuously funded by NIDDK since 7/1/1988, and the current competitive renewal extends from 7/1/2006 to 6/ | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $28,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to purchase a UV-Vis spectrophotemeter which will allow more sophisticated and useful spectrophotemetric assays. This, in turn, will accelerate and deepen the overall activities and success of the parent | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $77,422 | Grant | Trans-NIH Recovery Act Research Support: In the more than 2 decades that the NIH DK40344 grant has been ongoing, we have not requested NIH funds to purchase equipment needed for the project. This year, after 4 years of planning and construction, we are finally slated to move our laboratory to t | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $37,900 | Grant | Trans-NIH Recovery Act Research Support: This Supplement will provide a unique opportunity to accelerate the tempo of our research on a particularly important part of the project. The proposed experiments and their conceptual framework emerged from the robust progress we have made on Aim 1 durin | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $44,296 | Grant | Trans-NIH Recovery Act Research Support: How insulin binds to its receptor defines a central problem in molecular endocrinology. This competing application seeks to define the active structure of insulin and points of contact between the hormone and the a subunit of the insulin receptor (IR). We | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The long-range goal of this project is the detailed molecular characterization of the NaVl symporter (NIS), a key intrinsic plasma membrane transport protein that mediates the active translocation of l in the thyroid gland and other tissues. NiS plays a c | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,540 | Grant | Trans-NIH Recovery Act Research Support: An administrative supplement of ~$55,000 to grant R01 DK042303 (8/1/08 G?? 6/30/12) is requested under the ARRA to purchase a protein purification system and associated columns in order to address a substantially greater need for protein purification than | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $49,198 | Grant | Trans-NIH Recovery Act Research Support: his grant was an equipment supplement. We have purchased and received the three major items: Bio-Rad realtime PCR with reagents and a double head thermocycler Thermo ultra-low freezer Eppendorf refrigerated centrifuge. Payment for these items is in pro | Health and Human Services, Department of / National Institutes of Health | 11/27/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Insulin-like growth factors (IGFs) play key roles in normal muscle development in the fetus, are important for coordinating muscle regeneration following injury in the adult, and are critical for maintaining muscle mass during aging and in disease. The fo | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $87,241 | Grant | Trans-NIH Recovery Act Research Support: This request for a Recovery Act Administrative Supplement is to procure additional needed equipment to accelerate the tempo of scientific research under the parent grant 2R01DK043701-14A1 entitled G?Specific Repression of Prolactin Gene ExpressionG?. The | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $100,290 | Grant | Trans-NIH Recovery Act Research Support: Fanconi Anemia (FA) is an autosomal recessive cancer susceptibility disorder characterized by congenital abnormalities, bone marrow failure, and cellular hypersensitivity to DNA crosslinking agents. Nine FA genes have been cloned, and the nine encoded pro | Health and Human Services, Department of / National Institutes of Health | 11/18/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $11,000 | Grant | Trans-NIH Recovery Act Research Support: specific aims as listed in the original application: 1. Does insulin regulate hepatic glucose fliixes via activation of PI(3)K/Aktdependent pathways in the hypothalamus? We will examine whether stimulation of hypothalamic PI(3)K pathway is sufficient to r | Health and Human Services, Department of / National Institutes of Health | 12/31/2009 |
| SAINT FRANCIS HOSPITAL AND MEDICAL CENTER | $95,000 | Grant | Trans-NIH Recovery Act Research Support: Equipment | Health and Human Services, Department of / National Institutes of Health | 11/23/2009 |
| NEW YORK MEDICAL COLLEGE | $96,672 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that glutamine supplementation in mice chronically treated with non-pressor doses of L-NMMA, a model of early G?asymptomaticG? endothelial dysfunction, may improve mitochondrial function and metabolic profile of endothelial cells, eventuall | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $48,500 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplemental proposal is to seek additional funding to hasten progress on the aims of the parent grant by (i) supporting recruitment of a new research associate who has already been identified and (ii) by acquisition of instrumentation to | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $70,379 | Grant | Trans-NIH Recovery Act Research Support: We have developed an exciting new way of monitoring podocyte loss using a urine podocyte mRNA assay. We needed a non-invasive method to measure ongoing podocyte loss from glomeruli on a daily basis in order to measure podocyte stress and depletion as the | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $104,505 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this research is to comprehensively understand the mechanisms and regulation of intracellular protein. Protein degradation regulates nearly every aspect of normal cellular function. Dysfunction of protein degradation underlies many | Health and Human Services, Department of / National Institutes of Health | 12/22/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This application addresses the mechanisms by which prostaglandin (PG) signaling is terminated. PGs n signal a diverse array of cellular events. This signaling diversity requires that they be inactivated quickly n and over short distances. Evidence from ou | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| UNIVERSITY OF MARYLAND | $70,000 | Grant | Trans-NIH Recovery Act Research Support: The maturation of peptide hormones within secretory tissues such as the pancreas, pituitary and adrenal requires the participation of specific proteolytic converting enzymes, the prohormone convertases, and small convertase binding proteins such as 7B2 an | Health and Human Services, Department of / National Institutes of Health | 12/03/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $58,688 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Expression and function of the growth hormone receptor (GHR) is essential for the action of pituitary growth hormone (GH). The GH/IGF-1 axis plays a critical permissive role in the pathogenesis of chronic microvascular | Health and Human Services, Department of / National Institutes of Health | 12/04/2009 |
| UNIVERSITY OF ROCHESTER | $97,705 | Grant | Trans-NIH Recovery Act Research Support: Metabolic acidosis is a common but potentially life-threatening disorder that occurs when too much acid accumulates in the blood. The kidney is the organ that is primarily concerned with controlling the level of acid in the blood. The cortical collecting | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| EMORY UNIVERSITY | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an Administrative Supplement to parent grant R01 DK050740 entitled G?Muscle-specific nutritional adaptations to catabolic statesG? which is funded through 7/31/10. The aims of the grant are: 1) to study how FOXO1 and FOXO3a affect sk | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| THE WASHINGTON UNIVERSITY | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The ability of enterococci to form biofilms on abiotic materials, their propensity to acquire vancomycin-resistance, and their intrinsic antimicrobial resistance obviate the importance of ongoing research to combat these emerging and ubiquitous pathogens. | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $98,258 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of these studies is to understand general principles that govern normal and pathological CFTR folding in the endoplasmic reticulum (ER) membrane. Molecular mechanisms of membrane proteins biogenesis represent a poorly understood area o | Health and Human Services, Department of / National Institutes of Health | 12/27/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $196,847 | Grant | Trans-NIH Recovery Act Research Support: HMG-CoA reductase (HMGR) is the rate-limiting enzyme of sterol synthesis. HMGR is an integral membrane protein that undergoes regulated degradation by ER-associated degradation, or ERAD, in response to changing cellular demand for sterols. We originally s | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $80,258 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the parent project, DK52852, is to understand the regulation of the membrane trafficking pathway that shuttles the GLUT4 glucose transporter between intracellular storage compartments and the plasma membrane of adipocytes. Insul | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| NEW YORK UNIVERSITY (INC) | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The metabolic and growth-stimulatory effects of insulin are mediated by the insulin receptor, an a2,2 transmembrane glycoprotein with intrinsic protein tyrosine kinase activity. Insulin binding to the extracellular domains of the receptor induces a struct | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| EMORY UNIVERSITY | $103,100 | Grant | Trans-NIH Recovery Act Research Support: Title of grant: Regulation of pendrin by angiotensin II With this supplemental funding we are exploring the role of T and B lymphocytes in the regulation of pendrin by angiotensin II. Thus, we have been able to retain the services of Mr. Seongun Hong. Mor | Health and Human Services, Department of / National Institutes of Health | 12/08/2009 |
| DUKE UNIVERSITY | $129,897 | Grant | Trans-NIH Recovery Act Research Support: The primay goal of the parent grant is development of innovations in shock wave lithotripsy (SWL) technology. In the past two years, we have completed a series of experiments aiming at comparison of the characteristics of acoustic field, stone comminution | Health and Human Services, Department of / National Institutes of Health | 11/19/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $48,600 | Grant | Trans-NIH Recovery Act Research Support: This award provides additional funding to study the molecular basis of novel genetic forms of congenital hyperinsulinism (HI) in children. Previous years focused on the mechanisms of the hyperinsulinism / hyperammonemia syndrome associated with dominant, | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $97,795 | Grant | Trans-NIH Recovery Act Research Support: This award provides for funds to purchase two pieces of equipment: a table top ultracentrifuge and a FPLC chromatography system. Both pieces of equipment have been ordered. | Health and Human Services, Department of / National Institutes of Health | 12/14/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $64,249 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an administrative supplement to accelerate progress on studies described in the parent R01 award. The parent award addresses the hypothesis that ischemia and ATP depletion lead to activation of the AMP-dependent kinase (AMPK), w | Health and Human Services, Department of / National Institutes of Health | 12/18/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $99,901 | Grant | Trans-NIH Recovery Act Research Support: Urolithiasis is a multi-factorial disease and it is unlikely that a single factor will be responsible for the entire spectrum of this disorder. Nonetheless, oxalate and calcium-oxalate crystal (COM-crystal) interactions with renal epithelial cells, and th | Health and Human Services, Department of / National Institutes of Health | 11/20/2009 |
| UNIVERSITY OF MASSACHUSETTS | $98,998 | Grant | Trans-NIH Recovery Act Research Support: During the present and previous grant periods, our laboratory has comprehensively investigated the patterns of RNA expression in normal resting and activated neutrophils. These studies revealed remarkably vigorous transcriptional activity in neutrophils, | Health and Human Services, Department of / National Institutes of Health | 12/17/2009 |
| WAKE FOREST UNIVERSITY | $104,242 | Grant | Trans-NIH Recovery Act Research Support: Primary hyperoxaluria is a rare, genetic disorder that results from an excessive endogenous synthesis of oxalate. Glyoxylate reductase (GR) is a key enzyme in this biosynthetic pathway, converting glyoxylate, the main precursor of oxalate, to glycolate an | Health and Human Services, Department of / National Institutes of Health | 11/28/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $272,625 | Grant | Trans-NIH Recovery Act Research Support: Eukaryotes rely on mitochondria to produce ATP efficiently, yet this same organelle is the major source of reactive oxygen species (ROS), an endogenous toxin. Mitochondria! dysfunction has been associated with many disorders including type 2 diabetes, obe | Health and Human Services, Department of / National Institutes of Health | 12/21/2009 |
| NEW YORK MEDICAL COLLEGE | $100,965 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that stress-induced premature senescence (SIPS) is accompanied by subverted autophagy. To obtain direct proof of this hypothesis we propose to perform studies using intravital videomicroscopy of endothelial cells transfected with GFP-LC3 or | Health and Human Services, Department of / National Institutes of Health | 12/15/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY | $25,000 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to existing NIH grant 5 R01 DK054830 has been solicited by the Program Director, Dr. Catherine McKeon. It requests funds to expand the existing research in two ways: a) by purchasing new equipment, and b) re-directing the e | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| EASTERN VIRGINIA MEDICAL SCHOOL | $31,672 | Grant | Trans-NIH Recovery Act Research Support: There is an epidemic of diabetes in the United States today and the rates of diabetes development are predicted to increase further causing a major cost to our healthcare systems in terms of lives and dollars. Our research program is designed to identify | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The purchase of a new microscope will accelerate data collection and scientific output for our studies for this research project, all aims proposed rely on high resolution light microscopy, and fluorescence microscopy for the detection of various islet a | Health and Human Services, Department of / National Institutes of Health | 12/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $100,001 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will utilize recovery act funds to more quickly and completely achieve the goals of our NIDDK-funded research into Trafficking and Regulation of the Epithelial Na+ Channel. Specific Aim 1: To determine if channel endocytosi | Health and Human Services, Department of / National Institutes of Health | 12/07/2009 |
| EAST CAROLINA UNIVERSITY | $120,579 | Grant | Trans-NIH Recovery Act Research Support: A key feature of healthy skeletal muscle is an ability to adapt to changes in fuel supply. Accordingly, in the skeletal muscle of lean individuals, exposure to dietary lipid results in the activation of a global transcription program that enhances the ex | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $85,000 | Grant | Trans-NIH Recovery Act Research Support: Heat-shock protein 40 (Hsp40) plays essential roles in cell physiology since it cooperates with Hsp70 and Hsp90 to facilitate protein folding. The goal of the parent grant is to carry out X-ray crystallographic studies on Hsp40 to uncover the mechanisms b | Health and Human Services, Department of / National Institutes of Health | 12/30/2009 |