Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $48,358 | Grant | Trans-NIH Recovery Act Research Support: This proposal focusses on transcription initiation and elongation by bacterial RNA polymerase (RNAP). Transcription initiation and elongation involve a series of steps: (i) RNAP binds to promoter DNA, yielding an RNAP-promoter closed complex; (ii) RNAP un | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $94,098 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement was to purchase equipment essential to the project and to hire a postdoctoral research scientist to accelerate the tempo of one of the original aims of the research program. I have purchased a new gel documen | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $173,255 | Grant | Trans-NIH Recovery Act Research Support: In the last 3 months, we developed a method for quantitative analysis of the reactive oxygen species content in mitochondria as a function of position within the yeast cell. We performed ratiometric imaging of mitochondria-targeted GFP to dihydroethidium | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF TENNESSEE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: A significant component of the parent grant is the development and analysis of very complex and biologically realistic spatially and genetically explicit individual-based mathematical models of biological populations. One can say that the complexity of th | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $50,167 | Grant | Trans-NIH Recovery Act Research Support: Factors Stabilizing RNA Structures (supplement) - The primary purpose of the proposed supplement is the replacement of an aging UV spectrophotometer we use for measuring the free energy of RNA folding transitions. The poor quality of the data and the down | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $413,292 | Grant | Trans-NIH Recovery Act Research Support: Maintenance of the epigenetic marks (a set of specific, targeted covalent modifications of DNA and core histone proteins) during various nuclear processes is essential for survival and development of all eukaryotic cells. However molecular mechanisms main | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $49,159 | Grant | Trans-NIH Recovery Act Research Support: The supplement will provide funds for deep sequencing of mutant lines and for bioinformatic analyses of the data. The use of deep sequencing technology will greatly accelerate the pace of discovery for this project. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $85,000 | Grant | Trans-NIH Recovery Act Research Support: In this proposal, we focus on the mechanisms of assembly and disassembly of mitotic checkpoint complex (MCC). | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF NEW MEXICO | $58,175 | Grant | Trans-NIH Recovery Act Research Support: It is now broadly appreciated that the formation of specific tissues and organs within the body arises from the activity of a conserved regulatory network, primarily driven by transcriptional regulatory interactions. In Drosophila, mesodermal cells are in | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $185,897 | Grant | Trans-NIH Recovery Act Research Support: Acetaminophen (APAP) is the most commonly used medication in the United States but is also the most frequent cause of drug-induced hepatotoxicity. The long-term objective of this research is to elucidate the pharmacogenetic mechanisms that contribute to v | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ILLINOIS | $138,614 | Grant | Trans-NIH Recovery Act Research Support: This supplement will allow us to continue our progress in two areas. First, we determined whether our cheY mutants generated by gene shuffling have increased affinity for the target protein FliM in the activated and inactive forms. This information will a | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $140,251 | Grant | Trans-NIH Recovery Act Research Support: With the completion of the human genome project, it has become clear that the number of genes cannot account for the complexity of the human proteome. This conclusion has lead to a dramatic increase in our appreciation of the abundance and importance of | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The ARRA was a supplement to R01GM62437 which relates to basic science research on enzymes that are involved in epigenetics. Specifically, the award covered the purchase of major equipment used to allow more rapid progress toward achieving the specific ai | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $50,157 | Grant | Trans-NIH Recovery Act Research Support: The goals of our parent grant encompass the development and implementation of new methodology for directed evolution of enzymes, specifically glycosidases (with the potential for use in drug discovery and synthesis) and cellulases (with applictaions in bi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $91,041 | Grant | Trans-NIH Recovery Act Research Support: Lipoic acid is an essential sulfur-containing cofacor that is found in several multienzyme complexes that are involved in energy metabolism. In its functional form it is covaleritly attached to the epsilon amino group of a specific lysine residue on a des | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $213,629 | Grant | Trans-NIH Recovery Act Research Support: Retroviral Genomic RNA Dimer Structure and Function The long terms goals for the parent grant were motivated by the large consequences of retroviruses on human health. Retroviruses like HIV and HTLV are serious human pathogens and cause extraordinary mo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $246,178 | Grant | Trans-NIH Recovery Act Research Support: Endosomes segregate endocytosed macromolecules destined to be degraded in the lysosome from molecules that are either recycled back to the cell surface or routed to other intracellular organelles. The multivesicular body (MVB) is a late endosome that cont | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $255,157 | Grant | Trans-NIH Recovery Act Research Support: Most modern methods dealing with detecting genetic factors of complex human disorders require the usage of substantial markers. In our parent proposal (awarded 2005) we proposed to study and develop a fundamentally different approach that has shown promis | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $291,278 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic changes caused by DNA methylation, histone modifications and histone variants play crucial roles in the regulation of chromatin structure and genome stability, developmental specific gene regulation, genomic imprinting and transcriptional silen | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $197,488 | Grant | Trans-NIH Recovery Act Research Support: Phosphorylated inositol phospholipids (phosphoinositides) regulate a multitude of cellular functions via downstream lipid-binding effector proteins. Phosphoinositide-controlled processes include cytoskeletal organization, gene expression, cell proliferati | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF MARYLAND | $80,348 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Administrative supplement is to accomplish new objectives within the scope of the parent award that will 1) increase the scientific value of the project, 2) preserve the job of the current postdoc and 3) strengthen the data for a renew | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $142,599 | Grant | Trans-NIH Recovery Act Research Support: This Supplement to research grant R01GM072663 (G?The Electrochemistry of Diheme Cytochrome c Peroxidases) supports additional spectroscopic studies of bacterial cytochrome c peroxidase (CCP) enzymes, which are studied in the parent grant using electrochem | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $30,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The role of solid-state form in determining the properties of Pharmaceuticals is a critical issue in drug delivery. The ability of a solid to exist as more than one polymorph, supramolecular isomers that differ only in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CHICAGO, THE | $332,366 | Grant | Trans-NIH Recovery Act Research Support: Our proposalwill investigate the genetic and molecular basis of complex traits and their interactions with theenvironment using the model plant Arabidopsis thaliana. We will implement a multi use, high density oligo- nucleotide tiling array for whole geno | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $121,536 | Grant | Trans-NIH Recovery Act Research Support: The field of promoter prediction holds almost limitless potential, but has had very limited success. Instead of analyzing DMA sequence homology, we propose a novel method of eucaryotic promoter prediction based on the physical properties of DNA which aris | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| DUKE UNIVERSITY | $49,346 | Grant | Trans-NIH Recovery Act Research Support: Summary The Richardson lab tools for structure validation and correction are a powerful system for improving the accuracy of experimental 3D structures of protein and RNA, and are the critical components of the MolProbity web server. As assessors for the | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BROAD INSTITUTE, INC., THE | $64,000 | Grant | Trans-NIH Recovery Act Research Support: GenePattern is a freely available computational genomics environment, with over 11,000 users world-wide, that aims to bring advanced mathematical methods and computational algorithms for the analysis of microarray and other genomic data to the research co | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $78,909 | Grant | Trans-NIH Recovery Act Research Support: This supplemental effort would take advantage of an exciting collaborative opportunity to cap off the aims and accomplishments of the parent grant, while providing a major service to the biological and biomedical research communities and a job to a talent | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $142,901 | Grant | Trans-NIH Recovery Act Research Support: The research will provide fundamental understanding of the factors that prevent protein misfolding which is the cause of diseases like cyctic fibrosis and huntington's disease. The central hypothesis of the proposed research is that non-random structure | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $106,458 | Grant | Trans-NIH Recovery Act Research Support: Higher plants produce a diverse array of complex natural products many of which have potent anti-cancer activity. Unfortunately however the biosynthetic pathways that are responsible for the construction of these plant-derived molecules are not well und | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $163,091 | Grant | Trans-NIH Recovery Act Research Support: The proposed work focuses on basic structure/activity studies of two molybdenum-containing enzymes, xanthine oxidoreductase and carbon monoxide dehydrogenase. The first enzyme catalyzes the final two steps in purine metabolism in humans, and is also an im | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $76,054 | Grant | Trans-NIH Recovery Act Research Support: The general goal of the parent grant (1R01GM075315) is the molecular, genetic, and behavioral characterization of 3 Drosophila short sleeping lines (ss1, ss2, ss3). The first 3 specific aims of the project have not been modified, and a fourth aim was adde | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WASHINGTON UNIVERSITY, THE | $332,530 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to define the role of the cellular ESCRT machinery in the budding and release of intralumenal vesicles in multivesicular endosomes and in the topologically related process of viral budding. The specific aims are (1) to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $189,102 | Grant | Trans-NIH Recovery Act Research Support: We are currently in the last year of the parent grant and have made significant progress toward our stated goals. We have identified a number of novel cis-regulatory modules (CRMs) that support expression along the dorsoventral axis of developing Drosophi | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $35,650 | Grant | Trans-NIH Recovery Act Research Support: These studies address the fundamental mechanisms by which SUMO modification regulates gene expression in human cells. Altered SUMOylation is associated with cancer, neurodegeneration and other diseases in humans. Increased understanding of SUMO function | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $300,115 | Grant | Trans-NIH Recovery Act Research Support: Central biological functions such as replication, transcription, mRNA splicing, transport, and signaling are performed by molecular machines. Standard structural techniques fail to deal with the large size of molecular complexes and provide minimal dynami | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NEW YORK UNIVERSITY (INC) | $221,598 | Grant | Trans-NIH Recovery Act Research Support: Embryonic cells polarize to develop specializations needed for morphogenesis and differentiation. Using the C. elegans embryo as a simple model, our long-term goal is to understand how early embryonic cells acquire an inner-outer polarity that regulates t | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| BRIGHAM YOUNG UNIVERSITY | $168,126 | Grant | Trans-NIH Recovery Act Research Support: Heterotrimeric G proteins play a fundamental role in cell signaling by shuttling the ligand binding information received by G protein-coupled receptors (GPCRs) on the cell surface to effector enzymes and ion channels on the intracellular face of the plasm | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $253,808 | Grant | Trans-NIH Recovery Act Research Support: A central issue in healthy and diseased cells is how cells sense signals from the outside, and how these signals are used to organize cellular responses. The small GTPase families Ras and Rho are intimately involved in these processes, and mutations in th | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $300,834 | Grant | Trans-NIH Recovery Act Research Support: This award combines two supplemental requests: 1)Double-strand breaks (DSBs) are a major result of endogenous DNA replication errors and of exposure to exogenous DNA damaging agents, and failure to repair such breaks leads to the gross chromosomal rear | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $318,994 | Grant | Trans-NIH Recovery Act Research Support: This is a administrative supplement. It is for expansion of studies relating to the engagement of the heterotrimeric G protein G13 by Sonic hedgehog and other agonists as they relate to the activation of Gli transcription factors. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WASHINGTON UNIVERSITY, THE | $428,676 | Grant | Trans-NIH Recovery Act Research Support: Heterotrimeric G proteins (123) mediate the majority of signaling pathways in mammalian cells. It is long held that G protein function is localized to the plasma membrane. Observation of the spatio-temporal dynamics of G protein localization in living mam | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| BAYLOR COLLEGE OF MEDICINE | $115,125 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to initiate a new research direction for the PI in iPS field. The RFWD3 protein is originally identified as a putative ATM substrate in response to DNA damage. Subsequent biochemical analysis in our lab revealed that RFWD3 f | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| EMORY UNIVERSITY | $310,020 | Grant | Trans-NIH Recovery Act Research Support: This supplement request is to accelerate the process of the parent grant entitled G?A new role of MEPE/OF45 as a co-factor of CHK1 for DNA damage response,G? by hiring new employees. The research design/proposed scientific activities, methods and data ana | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $347,607 | Grant | Trans-NIH Recovery Act Research Support: This application requests supplemental funding for the parent grant 1 R01 GM081510, SIS Multicenter Study of Duration of Antibiotics for Intraabdominallnfection. The main purpose of these supplemental funds is to hire of an additional research coordinato | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $99,753 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement under the American Recovery and Reinvestment Act is to update our spinning disk confocal microcope with a motorized stage and faster camera to facilitate both Aims of the parent grant. These microscope updates will greatly i | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THOMAS JEFFERSON UNIVERSITY | $83,753 | Grant | Trans-NIH Recovery Act Research Support: This application is to seek a Recovery Act Administrative Supplement to the parent project, 1R01GM081601-1A2 G?Functions of tRNA modificationsG?, which investigates the mechanism of tRNA(m1G37) modification by the bacterial TrmD and the eukaryotic/archaea | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF FLORIDA | $156,307 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to understand the mechanism of Adeno-associated virus (AAV) receptor recognition and internalization. AAV is important both as a simple mammalian T=1 icosahedral virus model and also as a successful vector for human gene therapy that is recei | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $303,151 | Grant | Trans-NIH Recovery Act Research Support: Fires and burns are among the most common causes of death from unintentional injury. In the United States, almost 1.2 million burn injuries are reported annually and despite significant advances in burn care, infection remains a major cause of morbidity a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $138,600 | Grant | Trans-NIH Recovery Act Research Support: The capacity for tissue repair is a fundamental property of multicellular organisms that is often critical for survival. Despite its biological and clinical importance, the signals that initiate and terminate epidermal wound closure remain obscure, as do | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE JACKSON LABORATORY | $316,123 | Grant | Trans-NIH Recovery Act Research Support: Genetic recombination is responsible for the re-assortment of alleles at each generation; for our own species, this means the assortment of disease susceptibility alleles across generations and populations, and for all organisms, generating the substrates | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF IOWA, THE | $60,000 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of these studies is to better understand cell division in the model organism Escherichia coli. A deeper understanding of bacterial cell division is expected to facilitate the development of new antibiotics and will therefore benefit pub | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $215,416 | Grant | Trans-NIH Recovery Act Research Support: Acetylation of histone H4 N-terminal tail plays a crucial role in gene activation in chromatin environments; and alterations in this epigenetic process can lead to various diseases. Our long-term objective is to understand how H4 acetylation regulates p53 | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $180,117 | Grant | Trans-NIH Recovery Act Research Support: We are establishing C. elegans as a model for studying prostaglandin metabolism, genetic regulation, and biological functions. Using a combination of genetic analyses, in vivo bioactivity assays, and liquid chromatography-tandem mass spectrometry, we hav | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $291,870 | Grant | Trans-NIH Recovery Act Research Support: Proposal to focus on the production of G protein coupled receptors and their structural characterization by a novel NMR based approach. The requested funds will allow us to purchase equipment and hire additional technical help for the production of protei | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PURDUE UNIVERSITY | $207,077 | Grant | Trans-NIH Recovery Act Research Support: The proposed work focuses on the development of advanced methods in nuclear magnetic resonance (NMR) spectroscopy for metabolomics-based studies. The rapidly expanding field of metabolomics provides new information on biological perturbations based on mul | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF ARIZONA | $296,123 | Grant | Trans-NIH Recovery Act Research Support: The overall scope of the parent EUREKA grant is to characterize the structures of G-quadruplex/i-motif complexes found in promoter regions of a number of important genes involved in proliferation, apoptosis, and development, which will serve as a basis fo | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE WASHINGTON UNIVERSITY | $55,527 | Grant | Trans-NIH Recovery Act Research Support: In year 2 of the grant, we will have identified the ligand which binds to CG4395, synthesized it and raised antibodies to it. We originally planned to develop competitive ELISA assays to do this, using fluorescence detection. However, we recently isolated | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $178,735 | Grant | Trans-NIH Recovery Act Research Support: This project will develop software that is usefule for computational screening in drug discovery projects and takes advantage of otherwise idle computers. The Supplement will support the accelerated development and deployment of a distributed MM/PBSA prog | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF OREGON | $9,292 | Grant | Trans-NIH Recovery Act Research Support: Development of the central nervous system requires the production of the neuronal and glial cell types at the right place (spatial patterning) and at the right time (temporal patterning). Disruption of either spatial or temporal patterning can lead to emb | Health and Human Services, Department of / National Institutes of Health | 6/23/2009 |
| NORTHWESTERN UNIVERSITY | $154,115 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement will be used forjob creation,job retention, and procurement of additional needed equipment that will streamline data collection and analysis enormously. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON STATE UNIVERSITY | $85,424 | Grant | Trans-NIH Recovery Act Research Support: Errors during meiotic cell division are a leading cause of mental retardation and pregnancy loss in our species. The vast majority of human meiotic errors are maternal in origin and the rate of errors is strongly influenced by age. While the mechanism(s) | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The objective is to provide students, educators and researchers accurate, inexpensive and easily accessible visual data on human embryonic development. Aligned digital images of the serial sections of the best normal human embryos in the Carnegie collecti | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $10,950 | Grant | Trans-NIH Recovery Act Research Support: The award supported summer research of undergraduate student. It was a great educational opportunity for students, which allowed hands-on laboratory research experience and active contribution to laboratory work. In addition the student was able to partic | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| DUKE UNIVERSITY | $10,296 | Grant | Trans-NIH Recovery Act Research Support: While there are a number of surgical alternatives to autologous large diameter vascular grafts, i.e. allografts, xenografts, and synthetic vascular graft substitutes, there are no clinically acceptable alternatives to healthy autologous small diameter (<6 | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF HOUSTON SYSTEM | $24,969 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to structurally understand how the thromboxane A2 synthase (TXAS), coordinates (couples) with the upstream cyclooxygenase (COX) isoform-1 (COX-1) vs. isoform-2 (COX-2) in the biosynthesis of TXA2 (a key pro-thrombotic mediator | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| KENT STATE UNIVERSITY | $62,228 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the requested supplement was to promote summer job creation for faculty from a non-research intensive institution. The administrative supplement was awarded to Dr. Mary Russell, a science educator at the Trumbull campus of Kent state Unive | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF CINCINNATI | $67,510 | Grant | Trans-NIH Recovery Act Research Support: This application proposes to continue our studies of the Na,K-ATPase and is directed toward several ongoing goals. One of these is to test whether the cardiac glycoside binding site of the alpha2 or alpha3 isoforms of this enzyme, which is highly conserve | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $296,563 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Protein drugs are currently administered systemically by injections. For individuals requiring chronic therapy, self administration with a needle is an unpleasant everyday experience. Development of injectable biodegra | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS HEALTHCARE AT TYLER | $30,315 | Grant | Trans-NIH Recovery Act Research Support: Title: Structural Mechanisms of Factor IXa Function. The purpose of this award was to provide a summer research experience for a high-school or college level science teacher under NOT-OD-09-060 Administrative Supplement Notice for Students and Science Edu | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| THE VANDERBILT UNIVERSITY | $150,145 | Grant | Trans-NIH Recovery Act Research Support: The goal of this Administrative Supplement is to support the employment of additional laboratory personnel. Increased support is needed to bolster our efforts to identify and characterize genes that regulate oxygen sensing, smooth muscle responsiveness, | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $1,127,044 | Grant | Trans-NIH Recovery Act Research Support: Rapid advances in nanotechnology will be accompanied by the exposure of millions of individuals to products containing nanomaterials. Carbon Nanotubes (CNTs) are engineered nanomaterials designed for multiple uses (electronics, engineering, medicine), but | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $1,614,214 | Grant | Trans-NIH Recovery Act Research Support: Obesity and its complications are a major health concern in the US and other industrialized nations. Based on the coincident increase in industrial chemical production and the meteoric rise in body weight in recent decades, a mechanistic connection betwee | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $249,127 | Grant | Trans-NIH Recovery Act Research Support: NPCC is proposing to adopt Cancer 101 as one of its outreach and education activities. We will expand and update the Cancer 101 curriculum to reflect recent developments in cancer science, prevention, and treatment. We will also explore new ways of dissem | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DENVER HEALTH AND HOSPITALS AUTHORITY | $237,685 | Grant | Trans-NIH Recovery Act Research Support: Improving Patient Outcomes Through System Navigation Supplement - Build on the objectives of the parent Patient Naviation award through increasing education for the patient navigators and the community health educator. In addition, develop new training m | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $37,352 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer resaerch experience for three undergraduate students in health-related scientific research. The goal of this project is to develop a personal, self-contained circadian light and activity measurement device to correct sleep di | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| PONCE MEDICAL SCHOOL FOUNDATION INC | $261,857 | Grant | Trans-NIH Recovery Act Research Support: Endometriosis is a poorly understood gynecologic condition defined as the presence of endometrial tissue at ectopic sites. This condition is characterized by severe pelvic pain, dyspareunia, dysmenorrhea, and infertility. Endometriosis continues to incapa | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $63,765 | Grant | Trans-NIH Recovery Act Research Support: All vertebrates have internal asymmetries along the left-right (LR) axis, such as the asymmetric placement of organs about the midline. Correct asymmetric placement of organs is critical for their function, as it allows for proper connectivity within the | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $49,348 | Grant | Trans-NIH Recovery Act Research Support: The childhood obesity epidemic raises important clinical and public health questions about the effects of both obesity and obesity treatment on bone development. Osteoporotic fractures are a major cause of morbidity and mortality in the aged. However, pea | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. | $277,130 | Grant | Trans-NIH Recovery Act Research Support: The parent grant supports research to synthesize and analyze the major experimental early childhood intervention programs and non-experimental studies of family influence. Three tasks were delineated in the original proposal: (1) to put the intervention | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $124,146 | Grant | Trans-NIH Recovery Act Research Support: Congenital Diaphragmatic Hernia (CDH) is a frequent and often fatal developmental condition of diaphragm defects associated with lung hypoplasia caused by diverse factors that we hypothesize are predominantly genetic, but heterogeneous. Project IV will us | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF ROCHESTER | $41,931 | Grant | Trans-NIH Recovery Act Research Support: The supplement will provide detailed pharmaceutical data to determine if women who receive an epidural during delivery are at higher risk for premature breastfeeding termination or early supplementation with formula. The parent grant will use these findin | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF FLORIDA | $86,063 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the experiments performed in this laboratory are to identify the mechanisms controlling the activity of the hypothalamus-pituitary-adrenal (HPA) axis in fetal sheep. Providing a more complete understanding of the activity of the HPA ax | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $186,347 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to examine how a group of low-income parents from New Orleans, most of whom are single African American women, have coped with the effects of Hurricane Katrina. The 1,019 low-income parents in our sample are part of a random | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MIAMI | $11,157 | Grant | Trans-NIH Recovery Act Research Support: Novel Gene Targets for CNS Axonal Regeneration: Undergraduate research experiences are essential to providing important skills and encouragement for students to pursue careers in the health related sciences. These opportunities are often very difficult fo | Health and Human Services, Department of / National Institutes of Health | 7/09/2009 |
| MAYO CLINIC | $228,200 | Grant | Trans-NIH Recovery Act Research Support: The decline of contractility with ischemia - reperfusion is multifactorial. The parent grant, HL78845, aimed to define the root causes of the contractility decline by focusing on three specific aims: 1) To test the hypothesis that ischemia - reperfusion r | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $174,449 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long term objective of this work is to understand the mechanisms of genetically defined inherited cardiomyopathies in order to shed light on common mechanisms and devise therapies for cardiovascular disease in huma | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $243,004 | Grant | Trans-NIH Recovery Act Research Support: The reported association between an unfavorable fetal environment and adult diseases may be confounded by a genetic predisposition toward specific diseases (eg, vascular diseases) as the maternal genes that are transmitted o the fetus may also set the ute | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ROCHESTER | $237,695 | Grant | Trans-NIH Recovery Act Research Support: In this Administrative Supplement, we will examine the potential role of PECAM1 in fluid shear stress-mediated VEGFR2/Gab1/eNOS signal pathway, which is involved in flow atheroprective effects. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $196,269 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement to the parent R01. We propose to study a refined approach for quantification of contractile function of the heart. The supplement is expected to increase the tempo of scientific research and create one job position. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NEW YORK UNIVERSITY (INC) | $165,742 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent grant is to understand the relationship between sleep disordered breathing (SDB) and excessive daytime sleepiness in patients with obstructive sleep apnea hypopnea syndrome (OSAHS), at baseline and following therapy with C | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $230,280 | Grant | Trans-NIH Recovery Act Research Support: In the United States, homeless people number at least four million, a figure that is currently growing rapidly due to the recent rise in mortgage foreclosures across the nation. Despite progress made in reducing cigarette smoking in the general populatio | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $173,589 | Grant | Trans-NIH Recovery Act Research Support: This project award will retain a pre-doctoral graduate student (FTE). The overall aim of the parent grant (PG, HL081682) proposal is to determine the mechanisms by which calcium (Ca) signaling differentially regulates vascular smooth muscle cell (SMC) phe | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $254,764 | Grant | Trans-NIH Recovery Act Research Support: Aim 1 of the parent grant focused on characterizing the regulation and localization of several catenin proteins as a function of the hemodynamic environment in vitro and in vivo in the context of atherosclerosis. One of our major observations was that p1 | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $163,385 | Grant | Trans-NIH Recovery Act Research Support: The aims of this supplement are to to determine if genetic variation in thromboxane synthase, ET-1, or Rho-kinase determine six minute walk distance and response to therapy in PAH. Samples are undergoing genetic and statistical analysis currently.The | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF LOUISVILLE | $247,087 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to elucidate the regulation of mitochondrial turnover by O-GlcNAc signaling. Because O-GlcNAc is a metabolic signal, it may affect mitochondrial abundance during pathologic events, such as myocardial infarction (ischemia-repe | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $232,394 | Grant | Trans-NIH Recovery Act Research Support: We requested funds to hire a new staff member to assist us in adding polysomnography (sleep recording) and sleep scoring to these studies. This will expand the scope of the studies in the original grant. This new staff member will gain experience in cir | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE INC | $325,042 | Grant | Trans-NIH Recovery Act Research Support: The broad long-term objectives of the application are to determine the mechanisms by which the Severe Acute Respiratory Syndrome (SARS)-associated coronavirus (SCoV) causes acute lung injury and to identify new therapeutic strategies. The central hypothes | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| THE VANDERBILT UNIVERSITY | $15,500 | Grant | Trans-NIH Recovery Act Research Support: The student will participate in testing how different PAR agonists differentially regulate barrier function using ECIS in an endothelial cells as a model. We will further explore the ability of different PAR agonists to differentially regulate different G | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $191,634 | Grant | Trans-NIH Recovery Act Research Support: The parent application for this administrative supplement focuses on the mechanism by which inhaled carbon monoxide (CO) exerts its therapeutic actions in the mouse model of experimental pulmonary hypertension. In the process of conducting related experim | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $224,936 | Grant | Trans-NIH Recovery Act Research Support: Idiopathic pulmonary fibrosis (IPF) is characterized by fibroblast and myofibroblastic foci, and has excessive extracellular matrix protein accumulation. Focal-adhesion-kinase-related-non-kinase (FRNK) mediates integrin-mediated cell migration. This propo | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS HEALTHCARE AT TYLER | $204,647 | Grant | Trans-NIH Recovery Act Research Support: There is considerable interest in the mechanisms underlying the regulatio of transalveolar fluid clearance. The main goal of the parent grant is to study the contribution of the cGMP-activated +? ENaC-containing channels to transepithelial salt and fluid | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WRIGHT STATE UNIVERSITY | $182,786 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of the project, as mentioned in the parent grant proposal (1R01HL087795-01A1), is to utilize an ontology?]driven problem solving environment (PSE) for the human pathogen Trypanosoma cruzi. The PSE will enable the identification of vaccine | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MARYLAND | $203,406 | Grant | Trans-NIH Recovery Act Research Support: The treatment with cardiovascular medical devices enhances survival for many patients with otherwise hopeless medical conditions. Unfortunately, in many cases these devices cause dangerous pathological complications, in particular thrombosis and thromboem | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $21,555 | Grant | Trans-NIH Recovery Act Research Support: To develop a reproducible, bioreactor-based system to expand and differentiate adult bone marrow and skeletal muscle-derived side population (SP) stem cells to determine their regenerative and reparative potential. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF WASHINGTON | $254,533 | Grant | Trans-NIH Recovery Act Research Support: Intimal hyperplasia, which is caused by proliferation and migration of smooth muscle cells (SMCs), contributes to restenosis (the re-occlusion of vessels) after arterial reconstruction. We have recently found that carotid artery injury results in the form | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $125,568 | Grant | Trans-NIH Recovery Act Research Support: This supplement will advance our scientific discovery by accelerating data analyses on a funded-study involving approximately 620 adolescents, assessed in infancy, 3 to 5 years and 10 years as part of a NIH-supported cohort study of the behavioral and dev | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $24,587 | Grant | Trans-NIH Recovery Act Research Support: Mammals that hibernate depress their metabolic, heart and respiratory rates, as well as their core body temperature (Tb) to enter a state called torpor. In hibernators such as ground squirrels, torpor is precisely controlled and fully reversible using onl | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $290,211 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks supplemental funding through the Recovery Act to extend the Specific Aim #2 of the parent grant. Our long-term objective is to elucidate the endocytic trafficking pathways of the Cystic Fibrosis Transmembrane Conductance Regulator (CFT | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $341,536 | Grant | Trans-NIH Recovery Act Research Support: This application raises the possibility that the myocyte compartment of the embryonic, fetal and post-natal heart is generated by activation and lineage commitment of a pool of resident c-kit-positive cardiac progenitor cells (CPCs) which are clustered in | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ARIZONA | $236,455 | Grant | Trans-NIH Recovery Act Research Support: Deciphering how signals between cells coordinate heart development is essential for the diagnosis and treatment of congenital heart disorders. Our long-term goal is to gain a comprehensive understanding of how one of these signals, fibroblast growth facto | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $290,971 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement provides an opportunity for Dr. Manjunath Harlapur, a post-doctoral fellow, to receive high quality training in conducting patient-oriented translational research in the area of preventive cardiology. Dr. Harlapur?s research | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $345,523 | Grant | Trans-NIH Recovery Act Research Support: Sepsis is lethal, common, and expensive. The hospital case mortality rate for severe sepsis (sepsis plus organ dysfunction) is 30-50%; there are 751,000 cases of severe sepsis in the US annually at a cost of $17 billion. The endothelial response is emergi | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $209,552 | Grant | Trans-NIH Recovery Act Research Support: cDNA microarrays are a powerful tool to uncover genetic mechanisms underlying any condition. A major limitation is that the microarrays are not designed for rare species, such as in this grant, hibernating woodchucks. Accordingly this supplemental applic | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MIAMI | $159,120 | Grant | Trans-NIH Recovery Act Research Support: The incidence of congenital heart disease, including heart valve abnormalities, is approximately 1% of live births, and structural anomalies of heart valve leaflets and supporting structures are commonly observed. Mature heart valve structures are compose | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $15,777 | Grant | Trans-NIH Recovery Act Research Support: The challenges of warfarin therapy are significantly greater among patients with chronic kidney disease (CKD) and ESRD compared to that among patients with normal renal function. CKD can significantly reduce non-renal clearance and alter the bioavailabili | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $294,255 | Grant | Trans-NIH Recovery Act Research Support: Sepsis affects more than 300,000 individuals in the US annually, costs more than $16 billion/yr to treat, is associated with an acute mortality of 30%, and is expected to increase in incidence, making this disease a major public health concern. Care of th | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| THE VANDERBILT UNIVERSITY | $87,028 | Grant | Trans-NIH Recovery Act Research Support: The first goal is to train future investigators to characterize human genetic variation and its phenotypic implications. The research may be either direct studies of human traits or studies of animal models of human traits. The second goal is to provide s | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $183,084 | Grant | Trans-NIH Recovery Act Research Support: This program will train Ph.D. students at The Scripps Research Institute in the principles of evolutionary mechanisms in biological systems, and in the application of those principles in the laboratory to problems of biomedical science. ARRA funding will | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $87,028 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will enable support of the tuition and stipend of a student in the Computational and Systems Biology (CSB) Ph.D. Program, helping the program to maintain a critical mass of at least 6 students in each entering class. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| SAN FRANCISCO STATE UNIVERSITY | $99,909 | Grant | Trans-NIH Recovery Act Research Support: Purchase the equipment and provide supplemental instruction to build skills in reading for comprehension, writing, analyzing and representing scientific data. | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $60,584 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Alphaviruses and flaviviruses cause severe human and animal illnesses such as encephalitis, polyarthritis, and dengue fever, with millions of cases in humans per year. These viruses include many potential bioterrorist | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| CHILDREN'S MEMORIAL HOSPITAL, THE | $1,342,900 | Grant | Trans-NIH Recovery Act Research Support: Food allergy (FA), a condition caused by an immunoglobulin (Ig) E-mediated hypersensitivity reaction to food, is a growing clinical and public health problem in the U.S. and worldwide. FA affects approximately 5-8% children and 1-4% of adults. A positiv | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| DUKE UNIVERSITY | $2,583,504 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this research project is to improve the efficacy of anti-nicotine vaccination/immunotherapy for smoking cessation. The proposal relates to the special interest of NIDA in RFAOD- 09-004: G?Nicotine and Tobacco ResearchG? and addresses | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CINCINNATI | $1,349,819 | Grant | Trans-NIH Recovery Act Research Support: Despite increasing recognition that BPA has harmful effects on the reproductive, nervous and immune systems. While higher urine BPA concentrations are associated with cardiovascular disease in humans, the effect(s) of BPA at environmentally relevant conce | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BROAD INSTITUTE, INC., THE | $24,870,017 | Grant | Trans-NIH Recovery Act Research Support: We are embarking on contributing to a large catalogue of DNA sequence variation in phenotyped samples and to pioneering the application of this depth and scale of data to the analysis of key cardiovascular phenotypes. We propose to do this by (1) performi | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WASHINGTON | $7,654,551 | Grant | Trans-NIH Recovery Act Research Support: Twin studies have provided insights into multiple disease and developmental endpoints. Because their genetic and environmental similarities are easily understood, twins can elucidate the contributions of genetic and environmental factors to illness and he | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $1,334,969 | Grant | Trans-NIH Recovery Act Research Support: American Indians and Alaska Natives (AI/ANs) are at increased risk for Type 2 diabetes when compared to other Americans, a gap that continues to widen. Cardiovascular disease (CVD) has become the number one cause of death among AI/ANs, is now more common | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $34,560 | Grant | Trans-NIH Recovery Act Research Support: This proposed STEER program is intended to support the annual participation of eight academically talented undergraduates in the Environmental Health Sciences Summer Undergraduate Research Program (EHS-SURP). The overall goal of EHS-SURP is to provide an | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| CLARK ATLANTA UNIVERSITY, INC. | $190,691 | Grant | Trans-NIH Recovery Act Research Support: The goal of the MBRS RISE Program is to increase the number of young people who will enter biomedical fields. This supplement proposal will provide opportunities to implement a plan to strengthen and support the CAU RISE students while also providing new | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $181,948 | Grant | Trans-NIH Recovery Act Research Support: The Post-Baccalaureate Research Education Program (PREP) at the University of California Irvine (UCI) aims to increase the pool of admitted underrepresented minority graduate students by encouraging, orienting and better preparing recent baccalaureate rec | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| WAKE FOREST UNIVERSITY | $152,066 | Grant | Trans-NIH Recovery Act Research Support: This program is designed to provide interim positions for under-represented minority students and students from disadvantaged groups with post- baccalaureate degrees interested in pursuing graduate education. The focus is on research training under a stro | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $237,745 | Grant | Trans-NIH Recovery Act Research Support: The supplement is to enhance the University of Minnesota Duluth 'Pathway to Advanced Degrees in Life Sciences Program.' The program supplement will increase participation by underrepresented minorities in biomedical research. Program activities emphasize | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $128,812 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement focuses on the design and implementation of a comprehensive evaluation of the mobile laboratory program created by BUSM and replicated in substantially equivalent forms at SEPA and non-SEPA funded sites throughout the countr | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| MIAMI UNIVERSITY | $200,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The overriding goal of this Phase II project is to promote national dissemination of the Phase I HealthRICH products and resources, as these materials effectively encourage young teens and their families to make inform | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $292,249 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement to a NIH-NCRR Science Education Partnership Award (SEPA) grant, which is designed to teach high school students about clinical research. As part of the parent grant, a partnership was formed between the University of California | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| WASHINGTON UNIVERSITY, THE | $272,163 | Grant | Trans-NIH Recovery Act Research Support: The Siteman Cancer Center (SCC) Program for the Elimination of Cancer Disparities (PECaD) is a multidisciplinary community-focused program established to eliminate pervasive disparities of cancer education, prevention, and treatment. The SCC Senior Leader | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| AMHERST COLLEGE, TRUSTEES OF | $141,310 | Grant | Trans-NIH Recovery Act Research Support: Advances in obesity treatment may be provided by continued resolution of the neural circuits that mediate leptin, ghrelin, and insulin responses. Considerable recent research has detailed first and second order sites in hypothalamic regions that are sensi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $118,059 | Grant | Trans-NIH Recovery Act Research Support: Our aim is to compare the structure and function of different eukaryotic and archaeal Pus10 protein orthologs. We will bioinformatically identify candidate residues and structures, which confer Ø54 and Ø55 activity in Pus10 using homology model | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | $36,580 | Grant | Trans-NIH Recovery Act Research Support: The molybdenum cofactor (Moco) is a remarkable metal center that lies at the catalytic heart of a variety of enzymes. The unique and `universal' Moco has the same core structure in all mononuclear molybdenum enzymes (MMEs) and is found in all forms of lif | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CHICAGO, THE | $185,745 | Grant | Trans-NIH Recovery Act Research Support: Our parent grant, entitled G?Answering Information Needs in WorkflowG?, proposes to explore technologies to help clinicians articulate information needs that arise during clinical practice, and address them in a timely manner that fits with clinical workf | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $123,630 | Grant | Trans-NIH Recovery Act Research Support: Knowledge of protein function serves as a corner stone for biomedical research, which is fundamental for understanding biologic systems, the mechanism of disease and ultimately the human health. Decades of biomedical research has accumulated a great weal | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $249,239 | Grant | Trans-NIH Recovery Act Research Support: As new technologies such as virtual microscopes, multi-spectral imaging, and antibody-conjugated quantum dot probes (QD) continue to gain acceptance we have capitalized on the modular, flexible design of the imaging tools that we are developing so that wi | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $170,789 | Grant | Trans-NIH Recovery Act Research Support: The principal objective of this project is to develop methods that combine pathogen genotyping and patient epidemiology data that can be used in the control, understanding, and tracking of infectious diseases. | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $419,971 | Grant | Trans-NIH Recovery Act Research Support: Neurophysiological Studies of Schizophrenia: Translational Science: Innovative Targets and Models for Developing Treatments for Mental Disorders. The overall goal is the creation of an in vitro animal model of high frequency (gamma band; approx 40Hz) neoc | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $161,444 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application is the first competitive renewal of a project designed to understand the effects of abuse on children's brain-behavioral development. Studies of non-human animals have shown that adverse parental care | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $338,035 | Grant | Trans-NIH Recovery Act Research Support: Schizophrenia is currently thought to be a complex genetic disorder, with early developmental abnormalities in brain structure and function, being important in determining vulnerability to illness. This study will examine changes in smell abilities in sch | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $439,814 | Grant | Trans-NIH Recovery Act Research Support: Project Summary: Cortical circuits are composed of a complex network of many neuron types. Their function is dependent on how neurons are interconnected, how the connections function, and how the information delivered to individual neurons is integrated w | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| THE VANDERBILT UNIVERSITY | $31,644 | Grant | Trans-NIH Recovery Act Research Support: The parent grant is focused on identifying cognitive and neural components of working memory (WM) deficit, a core feature of schizophrenia (SZ). Since WM deficit is linked to poor social functioning and outcome, it is very important to develop treatment | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $88,432 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the present proposal is to develop, evaluate, distribute, and apply tools for quantitative meta-analysis of the human functional brain mapping (HFBM) literature. The BrainMap database may be used as an internet-based resource for | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $269,500 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision is to enlarge the scope of the current R01 - G??Dysfunctional Corticolimbic Activity and Connectivity in Bipolar Disorder' to also study at baseline 20 bipolar disorder (BD) patients in the euthymic state (BDE) and 40 unaffected | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CHICAGO, THE | $135,111 | Grant | Trans-NIH Recovery Act Research Support: This proposal describes a rational system for the identification of genes that controlnaturally occurring variability for fear conditioning (FC) in mice using a quantitative trait locus (QTL) mappingstrategy. As QTL strategies and technologies have mature | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $172,655 | Grant | Trans-NIH Recovery Act Research Support: The ARRA award provides supplemental funds to an existing research grant, ?Effectiveness Of A Depression Care Management Initiative In Home Healthcare? (R01 MH082425, PI: Martha L. Bruce). The goal of the research is to improve depression treatment and o | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $108,864 | Grant | Trans-NIH Recovery Act Research Support: Our principal objective is to identify genetic variation that underlies liability to schizophrenia and other psychotic disorders (henceforth called Scz) in the Oceanic population of Palau. We will accomplish this goal by capitalizing on a wide range of sc | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $149,840 | Grant | Trans-NIH Recovery Act Research Support: Chemotherapy, Pain, Sleep, Fatigue in Children and Parents Symptom management is a critical issue in both acute and chronic illness care. Studies with adults repeatedly demonstrate the deleterious effects of symptoms on health outcomes such as mood, physi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF MARYLAND | $99,262 | Grant | Trans-NIH Recovery Act Research Support: One of the most debilitating neurological complications of HIV infection is painful peripheral neuropathy (PPN) associated with nucleoside reverse transcriptase inhibitors (NRTIs). The predominant symptom, excruciating and unremitting pain, is resistant t | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $16,181 | Grant | Trans-NIH Recovery Act Research Support: This grant provides a summer research experience for one undergraduate student in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $118,800 | Grant | Trans-NIH Recovery Act Research Support: Award description: A fundamental question in neuroscience is to understand how inputs from our hands, eyes and ears are processed in the central nervous system. At the input level for each sensory system are arrays of receptors that are sensitive to diffe | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF CHICAGO, THE | $93,600 | Grant | Trans-NIH Recovery Act Research Support: Brain becomes more resilient to injury through activity, including that from spreading depression (SD). While, mechanisms for this intrinsic process remain undefined, they involve innate cytokines. Importantly, innate cytokines are redundant and pleiotrop | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| BAYLOR COLLEGE OF MEDICINE | $213,003 | Grant | Trans-NIH Recovery Act Research Support: Detrmine how Caicua modifies the course of SCA1 and to uncover the molecular functions of Ataxin1. ABSTRACT: Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disorder caused by expansion of a CAG repeat that encodes glutamine in Ataxin-1. Our | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $110,779 | Grant | Trans-NIH Recovery Act Research Support: Nicotinic acetylcholine receptors (nAChRs) are essential to behaviors as basic as breathing and as mysterious as motivation, memory and mood. Loss of cholinoceptive sites, evident as decreased nAChRs and deterioration of central cholinergic projections ar | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $4,680 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement for a Summer Undergraduate Student for RO1 NS032401, G?PACAP Regulation of Neurogenesis and SurvivalG? (PI: E. DiCicco-Bloom). I requested this supplement so that we may 1) accelerate the tempo of scientific research and 2) crea | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $114,996 | Grant | Trans-NIH Recovery Act Research Support: The neuronal ceroid lipofuscinosis (NCLs) are recessively inherited childhood disorders, with an incidence of approximately 1:12,500 in the U.S. NCL is a problem of selectively impaired mitochondrial autophagy, as neuronal cells in the CNS feature the acc | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $29,964 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this award was to examine the effects of lesions to specified areas in posterior parietal cortex. We examined the effects of lesions to area 5 on two well defined manual and bimanual behaviors, as well as the effects that this les | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $20,849 | Grant | Trans-NIH Recovery Act Research Support: Songbirds provide an animal model for human speech perception and production, and for developmentally restricted forms of learning and memory, in which it is possible to causally link specific behaviors and their underlying neural circuitry. Birds, like h | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $31,255 | Grant | Trans-NIH Recovery Act Research Support: Mental retardation is a prominent clinical feature of the lysosomal storage disorders (LSD's), due to the severe pathology in the central nervous system (CNS). The LSD's constitute a significant number of the human genetic diseases that affect the CNS. Th | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| NEW YORK UNIVERSITY (INC) | $245,672 | Grant | Trans-NIH Recovery Act Research Support: Thalamic injury has been poorly investigated in mild traumatic brain injury (MTBI). The thalamus is important to communication among many associative brain regions including sensory, motor, cognitive, and behavioral functions; it is one of the key element | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $200,744 | Grant | Trans-NIH Recovery Act Research Support: Our currently funded studies from NINDS were designed to test the overall hypothesis that rapid rotations of the immature brain (as associated often with abuse, motor vehicle accidents and falls) produce brain injury via both mechanical and biochemical si | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $161,954 | Grant | Trans-NIH Recovery Act Research Support: Regulatory T cells (Tregs), a special subset of T cells, serve as a primary regulator for immune response. The major function of Tregs is to oppose and control Th1, Th2 and Th17 cells. Here we will test a novel hypothesis that in addition to controlling T | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $97,890 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant is to perform cognitive neuroscience experiments using electrocorticographic ECoG recordings in human subjects (EEG recorded from the brain surface with electrodes surgically implanted for epilepsy surgery). These reco | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $22,096 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to provide (1) a summer research experience for an undergraduate student with an interest in pursuing a career in neuroscience and to accelerate the tempo of work on the parent grant. The hypothesis of the parent proposal is that a | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| MONTEFIORE MEDICAL CENTER | $281,653 | Grant | Trans-NIH Recovery Act Research Support: Temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) is often associated with a history of febrile seizures (FC). However, the proposed causal relationship between FCs and MTS remains controversial. Identification of children at high risk to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $147,600 | Grant | Trans-NIH Recovery Act Research Support: The competitive award was requested to explore the role of mitochondria in HIV neuropathy and specifically the interaction between HIV envelope protein gp120 and mitochondrial function in causing distal axonal degeneration. We have already obtained prelim | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $180,087 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): The specification of cell types in the ventral hal | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $76,708 | Grant | Trans-NIH Recovery Act Research Support: Viral-induced encephalitis remains a major cause of morbidity and mortality throughout the world. Effective therapies are available for only a few neurotropic viruses, and even when these infections are optimally treated, residual mortality and neurologic | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $50,836 | Grant | Trans-NIH Recovery Act Research Support: Our research program is toward the understanding of molecular basis of myelin regeneration and repair after injury in the central nervous system. This critical event is facilitated by specialized cells called oligodendrocytes, which insulate axons, facil | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $153,687 | Grant | Trans-NIH Recovery Act Research Support: We are requesting an Administrative Supplement to our Grant ?Neurotoxins from Marine Algae and Cyanobacteria? (NS053398) so as to increase the pace and tempo of the research on aims previously approved in peer review. The broad, long term objectives of | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $97,346 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is slated for upgrading a spinning disk confocal microscope for live cell imaging. So far, we have purchased from Morrell Instrument Company a 60x Nikon lens ($10,020), which will allow us to visualize the entire dendritic | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF IOWA, THE | $102,079 | Grant | Trans-NIH Recovery Act Research Support: In addition to their bioenergetic function, mitochondria are critical regulators of Ca signaling in neurons. Mitochondria efficiently buffer Ca2+ influx during excitation and limit the amplitude of the cytosolic Ca2+ concentration ([Ca2+]i) increase. Rapi | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| BAYLOR COLLEGE OF MEDICINE | $199,550 | Grant | Trans-NIH Recovery Act Research Support: Study the consequences of loss of MeCP2 function in cholinergic neurons. ABSTRACT: Rett Syndrome (RTT) is a devastating neurological disorder characterized by autistic features, cognitive impairments, motor abnormalities, seizures, and autonomic dysfunct | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| EMORY UNIVERSITY | $183,749 | Grant | Trans-NIH Recovery Act Research Support: Title: Combination therapy in human ES cell transplantation after neonatal stroke Embryonic stem cell transplantation has been widely investigated as a novel therapeutic strategy in ischemic stroke. The original Specific Aims address three key issues in s | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $207,468 | Grant | Trans-NIH Recovery Act Research Support: Among the billions of neurons and glia in the vertebrate central nervous system (CNS) is a rich milieu of extracellular matrix (ECM) proteins. Most CNS cells interact with ECM components via members of the integrin family of cell surface adhesion receptor | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $42,742 | Grant | Trans-NIH Recovery Act Research Support: Spinal cord injuries with consequent paralysis affect more than 250,000 people in the US and several million worldwide. The biological causes that prevent axonal regeneration to occur in the central nervous system (CMS) are still elusive. The lack of expe | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| UNIVERSITY OF IOWA, THE | $31,653 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to understand the role of the Sen1 helicase in termination of RNA Polymerase II (PolII) transcripts and to establish how mutations in the human homolog of Sen1, Senataxin (SETX), cause the neurodegenerative disorders Ataxia-Oc | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MARYLAND | $70,711 | Grant | Trans-NIH Recovery Act Research Support: There are persistent questions regarding the evolution and function of the immune system. Previously studies performed in non-mammalian vertebrates have helped to reveal basic features of the immune system that are universal. In other cases, studies outsi | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $330,697 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to determine the biological mechanisms that regulate male-typical sexual partner preference, and, thereby, to develop a better understanding of mammalian sexual differentiation and psychosexual development. The successful coun | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $303,529 | Grant | Trans-NIH Recovery Act Research Support: This research proposal is a revised R01 application in response to the Program Announcement Continued Development and Maintenance of Bioinformatics and Computational Biology Software for five years of funding to continue development and maintenance of an | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $93,854 | Grant | Trans-NIH Recovery Act Research Support: The present proposal is aimed at incorporating the newly developed cross-correlation light scattering capability with synchrotron X-ray scattering, specifically designed for bio-macromolecular gels, solutions and suspensions. The combined X-rays and laser | Health and Human Services, Department of / National Institutes of Health | 8/25/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $202,649 | Grant | Trans-NIH Recovery Act Research Support: Researchers in bioinformatics and computational biology (BCB) continue to require virtually unbounded high performance computing (HPC) capability: New scientific insights emerge with each significant advance in HPC technology. The current HPC generation | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| GEORGETOWN UNIVERSITY (THE) | $76,750 | Grant | Trans-NIH Recovery Act Research Support: This supplemental grant supports our investigation of ApoEr2?s interaction with the protein Reelin, and the effects of this interaction on synapse and dendritic spine formation (which are known to be important for learning and memory) in the brain. We ar | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| EASTERN VIRGINIA MEDICAL SCHOOL | $57,400 | Grant | Trans-NIH Recovery Act Research Support: Supplement to NIH R03 award to advance progress on the analysis of human cytomegalovirus tegument proteins. This will be accomplished through the hiring of a new research assistant | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF LOUISVILLE | $18,254 | Grant | Trans-NIH Recovery Act Research Support: This supplement supported an undergraduate summer research student. The project is ongoing, and involves back-crossing knockout mice into another genetic background. He performs genotyping and overall maintenance of the colony. His work has progressed t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | $26,680 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 2 undergraduate college students in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $7,725 | Grant | Trans-NIH Recovery Act Research Support: The P.I. proposes to study the role of auditory perception in mediating vocal learning in a songbird, the zebra finch. Young male zebra finches learn their songs from adult models through a process of imitation that resembles human speech acquisition. As | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $56,918 | Grant | Trans-NIH Recovery Act Research Support: The cochlear microcirculation is essential for normal hearing. A reduction of cochlear blood flow is involved in a number of hearing disorders. Pericytes, surrounding blood microvessels, play important roles for many organs in the regulation of microvesse | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| EASTERN VIRGINIA MEDICAL SCHOOL | $71,750 | Grant | Trans-NIH Recovery Act Research Support: Myosin VIIA is a cellular motor protein which is expressed in a several tissues including the inner ear and the retina. Mutations in the myosin VIIA gene are associated with a variety of sensory neuronal disorders including the Usher syndrome 1B, characte | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WAKE FOREST UNIVERSITY | $70,670 | Grant | Trans-NIH Recovery Act Research Support: The basic functional of the auditory system is to allow listeners to detect signals in quiet as well as noisy environments. The ability to detect sounds in noisy environments is compromised in the elderly and the hearing impaired. The representation of si | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $10,616 | Grant | Trans-NIH Recovery Act Research Support: This supplement is for 5R03HD055216-02, ?Mothers' attitudes about elective cesarean: results, expectations & satisfaction? (MADRES).-? The original goals of the MADRES study were to study the attitudes and expectations of pregnant women with respect to ch | Health and Human Services, Department of / National Institutes of Health | 5/27/2009 |
| WASHINGTON UNIVERSITY, THE | $75,812 | Grant | Trans-NIH Recovery Act Research Support: This RO3 addresses the fundamental question related to gonadotropin secretion from the anterior pituitary. Specifically, why FSH is secreted constitutively and LH is primarily released through the regulated pathway. This is an intriguing issue since bot | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | $65,400 | Grant | Trans-NIH Recovery Act Research Support: Novel Intracellular Pattern Recognition Receptor Expression by Resident CNS Cells While glial cells are recognized for their roles in maintaining neuronal function, there is growing appreciation of the ability of resident brain cells to initiate and/or r | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY ENTERPRISES, INC. | $17,664 | Grant | Trans-NIH Recovery Act Research Support: Fund two undergraduates and one high school student for summer resesarch. These students will be working on the synthesis of novel glycodendrimer structures (undergraduates) and the generation of quantitative amounts of oligomeric sugars to be used for g | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| SAINT LOUIS UNIVERSITY | $3,248 | Grant | Trans-NIH Recovery Act Research Support: This project investigates the potential of targeting two amino acid transporters, ASCT2 and LAT1, as therapy for human hepatocellular carcinoma (HCC), and to determine their role in HCC development and growth. The incidence of HCC is on the rise in the Un | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $70,000 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement award to the existing parent R-15 grant (R15CA119253) that was awarded for a 1-year period. The objective of this administrative supplement award is to purchase an equipment (intensified charge coupled device, ICCD, | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $983,634 | Grant | Trans-NIH Recovery Act Research Support: This project is significant as it addresses scientific knowledge gaps in sophisticated quality of life and neurocognitive assessment tools, specifically the Neuro-QOL and the NIH Toolbox neurocognitive battery, through the use of a well-controlled psychom | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $856,378 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Analysis of Neural Circuits using a Genetically-encoded Silencer. Two postdoctoral students and one research technician will direct their effort to generate the constructs requited to generate these mice and to carry out analysis. The mice | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WGBH EDUCATIONAL FOUNDATION | $960,349 | Grant | Trans-NIH Recovery Act Research Support: The Hastings Center (the nation's first and foremost bioethics research organization), NOVA (the nation's most-watched science program) and WGBH (PBS's leading producer of programming) have partnered to research whether a multi-platform media project can | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $971,784 | Grant | Trans-NIH Recovery Act Research Support: Research and Treatment in Comparative Effectiveness, Quality Improvement (QI) and Investigational New Drugs (IND) Research examines the research-treatment interface in the context of traditional clinical trials, comparative effectiveness research, and qua | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $1,009,959 | Grant | Trans-NIH Recovery Act Research Support: Current experimental evidence supports a J- or U-shaped association between alcohol consumption and heart attack and/or high blood pressure. As such, while light-to-moderate drinking has been associated with protection from heart disease, heavy drinking i | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $23,822,294 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to determine the clinical, cognitive, imaging, genetic, and biochemical biomarker characteristics of the early (pre-dementia) stages of Alzheimer's disease (AD). The project builds on the NIA-funded AD Neuroimaging Initiative (ADNI1) and serve | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $5,227,290 | Grant | Trans-NIH Recovery Act Research Support: The recent report that rapamycin increases the lifespan of mice is a major breakthrough in aging because it can be translated easily to humans. However, the critical question is whether long-term rapamycin treatment improves healthspan/quality-of-life as | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $2,654,871 | Grant | Trans-NIH Recovery Act Research Support: The major goal of this project is to assess the associations of genetic markers with cognitive decline among older African Americans and Africans so as to identify genetic factors that are related to this problem. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CLEVELAND BIOLABS, INC. | $5,329,543 | Grant | Trans-NIH Recovery Act Research Support: The severity of radiation injury in humans is largely determined by high sensitivity of the gastrointestinal (GI) tract, yet no drugs are approved for this indication. This award is focused on a novel, clinical-stage drug candidate, Protectan CBLB502, a T | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ILLINOIS | $1,231,805 | Grant | Trans-NIH Recovery Act Research Support: Natural products and nature-derived materials continue to represent major analytical challenges in biomedical research. Their innate chemical complexity is of biogenetic origin, and can obscure correlations between chemical structures and observed biologi | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF WASHINGTON | $992,785 | Grant | Trans-NIH Recovery Act Research Support: This RC2 proposal is responsive to this Specific Topic because: 1) It focuses on an often lethal but rare disease: Merkel cell carcinoma (MCC), with prevalence of well under 200,000 cases in the US. 2) We will generate preliminary results that evaluate th | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $2,653,695 | Grant | Trans-NIH Recovery Act Research Support: The class IA phosphatidylinositol 3 kinase (PI3K) signaling axis is perhaps the most frequently activated pathway in human cancer. In response to the activation of receptor tyrosine kinases (RTKs), G-protein coupled receptors (GPCRs) or Ras, class IA PI3K | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $4,001,033 | Grant | Trans-NIH Recovery Act Research Support: Through a partnership between investigators in the Cancer Research Network (CRN) and Dana-Farber/Harvard Cancer Center, we propose to develop a resource with sufficient depth and breadth to support high quality cancer comparative effectiveness research (C | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $3,962,575 | Grant | Trans-NIH Recovery Act Research Support: Emerging imaging technologies are an important component of efforts to effectively detect and treat cancer. The American Recovery and Reinvestment Act of 2009 specifically targets the development of comparative effectiveness research (CER) to increase the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $1,303,720 | Grant | Trans-NIH Recovery Act Research Support: 1. We purchased and received a mass spectrometer and have developed protocols for using it to sequence peptoids. 2. We successfully created an on-bead 5-mer peptoid library with individual library members composed of all combinations of ten possible mono | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $989,312 | Grant | Trans-NIH Recovery Act Research Support: Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is the etiologic agent of Kaposi's sarcoma (KS), and other proliferative disorders. KS was one of two sentinel diseases that heralded the AIDS epidemic. Althought the level of KS has | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $1,181,792 | Grant | Trans-NIH Recovery Act Research Support: The central goal of this GO RC2 application is to leverage the collective resources of three institutions (VCU/Massey Cancer Center, MD Anderson Cancer Center, H. Lee Moffitt Cancer Center) and various associated support mechanisms (i.e., R01, P01, N01, a | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $2,033,332 | Grant | Trans-NIH Recovery Act Research Support: Cancer is a disorder of unrestrained cell proliferation, but increasingly it seems that not all proliferating cells in a tumor matter equally. As with cells in normal tissues, tumor cells appear to progress through lineage stages, in which the capacity fo | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $1,440,000 | Grant | Trans-NIH Recovery Act Research Support: This grant is responsive to recent data suggesting that bisphenol A (BPA) may contribute to asthma, possibly through heightened inflammation and T regulatory cell dysfunction. Preliminary data show a dose-dependent association between early-life BPA expos | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $784,125 | Grant | Trans-NIH Recovery Act Research Support: While it is now recognized that the manufacture of nanomaterials may present unique risks to humans and the environment, the field of nanotoxicology remains at an early stage. Nanomaterials, the building blocks of nanotechnology, constitute a very diverse | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| THE VANDERBILT UNIVERSITY | $6,406,203 | Grant | Trans-NIH Recovery Act Research Support: An important potential enabling resource for Personalized Medicine is the combination of a DNA repository with Electronic Medical Record (EMR) systems sufficiently robust to provide excellence in clinical care and to serve as resources for analysis of dis | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| COLD SPRING HARBOR LABORATORY | $2,979,908 | Grant | Trans-NIH Recovery Act Research Support: Mammalian development is driven by the successive restriction of developmental potential as the totipotent zygote generates the diversity of mature cell types present within an adult animal. The characteristics adopted by each cell within the animal are s | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| EMORY UNIVERSITY | $3,423,980 | Grant | Trans-NIH Recovery Act Research Support: Title: CNV Atlas of Human Development Abstract: The recent discovery that copy number variations (CNVs), the loss or gain of small genomic segments, is common in all normal individuals and plays a major role in human phenotypic variation and disease, has | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SEQUOIA FOUNDATION | $3,400,776 | Grant | Trans-NIH Recovery Act Research Support: Population-based biobanks are a critical resource for identifying disease mechanisms and developing screening tests for biomarkers associated with certain disorders. The California Department of Public Health has been banking newborn specimens statewide | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $1,472,257 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): DNA sequencing is currently in the midst of disruptive technological shifts, with 454, Illumina, and Solid providing us with enormous throughput increases and large reductions in cost per base. Massively parallel tech | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | $1,190,022 | Grant | Trans-NIH Recovery Act Research Support: In this program, we will enable direct DNA methylation profiling during real-time DNA sequencing, without bisulfite conversion. We will accomplish this by tailoring Pacific Biosciences? high throughput Single-Molecule Real-Time (SMRT) DNA sequencing techn | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| INSTITUTE FOR SYSTEMS BIOLOGY | $4,576,646 | Grant | Trans-NIH Recovery Act Research Support: Personalized medicine will depend on molecular signatures to match the right patients to the right drugs, first in clinical trials, then in clinical practice. Personalized medicine is a new paradigm in which information technology, science, and clinical t | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $1,817,442 | Grant | Trans-NIH Recovery Act Research Support: This stage one TRIP application will enable a phase II clinical trial of a new therapy to treat sickle cell disease (SCD) in two years. The basis of our proposal is our recent discovery that invariant NKT (iNKT) cells contribute importantly to tissue infl | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $3,297,821 | Grant | Trans-NIH Recovery Act Research Support: Hutchinson-Gilford Progeria Syndrome (HGPS or progeria) is a rare autosomal dominant 'premature aging' disease. Children die at a median age of 13 years due to heart attacks and strokes caused by accelerated, global arteriosclerosis. The HGPS mutation lie | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $7,915,507 | Grant | Trans-NIH Recovery Act Research Support: Patient recruitment and retention Patient recruitment and retention of study subjects has been excellent in this study. The COMET Network was able to screen 108 potential subjects. From these there were 12 screen fails, 3 subjects withdrew consent, two | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $3,432,177 | Grant | Trans-NIH Recovery Act Research Support: Comparative phenotypic, functional, and molecular analysis of pluripotent stem cells arguably the most significant challenge in stem cell biology today is determining whether human induced pluripotent stem cells (hiPSC) are truly equivalent to human embry | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $1,334,973 | Grant | Trans-NIH Recovery Act Research Support: Chronic illness and health disparities are prevalent in the United States. More than 61 million Americans have heart disease, 20 million have diabetes, 50 million have hypertension, and 7.4 million have kidney disease. Those from racial and ethnic minorit | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF FLORIDA | $12,201,380 | Grant | Trans-NIH Recovery Act Research Support: The proposed work will establish national networking of scientists by providing a new software system (VIVO) and support for scientists using VIVO. Scientists using VIVO will be able to find other scientists and their work. Conversely, scientists using | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NORTHWESTERN UNIVERSITY | $1,200,000 | Grant | Trans-NIH Recovery Act Research Support: This proposed Patient-Reported Outcomes Measurement Information System (PROMIS) Statistical Center (PSC) will advise and educate members of the network on a range of qualitative research methods; develop and implement processes to ensure data quality; pro | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $58,852 | Grant | Trans-NIH Recovery Act Research Support: The broad, long term objective of the parent proposal, Sequence Acquisition from Mapped Single DNA Molecules, is to develop a scheme for acquisition of sequence information using large genomic DNA molecules. Sequence information is revealed by imaging str | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $112,260 | Grant | Trans-NIH Recovery Act Research Support: In vascular diseases, contractile genes are often downregulated in smooth muscle cells (SMC). A crucial regulator of their expression is a complex involving coactivators of the Myocardin family recruited to a conserved DNA sequence, the G??CArG-boxG??. Th | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $100,800 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Cardiomyopathy and heart failure are potentially fatal complications of diabetes, but the molecular mechanisms leading to diabetes-induced cardiomyocyte damage are not well understood and therapies targeting these proc | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NATIONAL ASSOCIATION OF COUNTY AND CITY HEALTH OFFICIALS | $1,222,811 | Grant | Trans-NIH Recovery Act Research Support: Convincing evidence of the importance of the social determinants of health and health inequity continues to be documented. Relatively few students and even fewer health practitioners, however, receive training in taking action. Healthy People 2010, with h | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WESTAT, INC. | $1,334,969 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the project is to develop and test new performance measures in community care coordination using the Pathways Model as the framework for developing the measures. There are four major goals for this project, which are to: (1) refine the log | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $3,378,613 | Grant | Trans-NIH Recovery Act Research Support: Major depressive disorder (MDD) is the leading cause of disability in the world (WHO). The severe, recurrent form often onsets during childhood or adolescence and becomes chronic. Heritability (35-70%) is similar to that of other common disorders for whic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | $3,453,837 | Grant | Trans-NIH Recovery Act Research Support: Common and Rare Genetic Factors in an Ethnically Homogeneous Schizophrenia Cohort: This project aims to perform a genomewide association study (GWAS), as well as extensive next-generation resequencing, in a large cohort of Ashkenazi Jewish patients with | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $10,071,173 | Grant | Trans-NIH Recovery Act Research Support: Advances in genomics are revolutionizing medicine with novel discoveries that help understand mechanisms and design novel treatments. For mental illnesses to join genomics we need robust phenotypic developmental data linked to brain function. The goal of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRANSLATIONAL GENOMICS RESEARCH INSTITITUE, THE | $7,551,983 | Grant | Trans-NIH Recovery Act Research Support: Advancing new therapeutic targets into innovative drugs is a major translational bottleneck in the southwestern United States. To address this urgent need, we aim to build a critical resource closing major medicinal chemistry resource gaps for our region | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MIAMI | $2,615,045 | Grant | Trans-NIH Recovery Act Research Support: Proteomics remains virtually without context. The project will show context-specific proteomic maps of wild type neurons in the intact brain, furnishing a much-needed intellectual infrastructure to transform definitions of the molecular circuitries affec | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $631,183 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Evaluation of research effort, such as estimation of the proportion of treatment successes in clinical trials, has important ethical, scientific, and public policy implications. Researchers, policymakers, funding agenc | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $684,700 | Grant | Trans-NIH Recovery Act Research Support: Histone deacetylases (HDACs) are enzymes that regulate the functions of histone proteins by catalyzing the removal of acetyl groups from lysine residues. They play a pivotal role in the regulation of gene transcription and are indispensable in numerous eu | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $800,000 | Grant | Trans-NIH Recovery Act Research Support: Onchocerciasis is a debilitating disease caused by infection with the parasite Onchocerca volvulus. The public health importance of onchocerciasis has been recognized by the international community, which has sponsored several programs whose goal (dependi | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $150,000 | Grant | Trans-NIH Recovery Act Research Support: Colorectal cancer is a preventable yet highly prevalent disease worldwide. Poor patient compliance with screening procedures increases the mortality due to colorectal cancer. There is an urgent need for chemopreventive measures for this tumor type. One of | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $253,515 | Grant | Trans-NIH Recovery Act Research Support: This award will provide partial support for the acquisition of a Biacore T100 surface plasmon resonance system at the University of Texas Medical Branch (UTMB) in Galveston. Molecular recognition is one of the most important problems in biology and medici | Health and Human Services, Department of / National Institutes of Health | 4/27/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This application covers the acquisition of a quadrupole time-of-flight (Q-TOF) ion mobility hybrid mass spectrometer. This instrument will be added to an existing core facility in the University of Georgia, College of Pharmacy and be directly involved in | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This award was for the purchase of a Illumina GAIIx high-throughput sequencer. (HTS) | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This is an instrumentation grant. Every cell and tissue biology research program has needs for microscopic visualization of research specimens. While some of these needs are best addressed by traditional, routine light and confocal microscopy of thin, fix | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $295,533 | Grant | Trans-NIH Recovery Act Research Support: Ultrasound offers unique capabilities for investigating tumor development in terms of anatomy and perfusion. The new instrument will accelerate development of new therapies in our institution, which will be directly translatable to the clinic, and thus, p | Health and Human Services, Department of / National Institutes of Health | 4/28/2009 |
| COLORADO STATE UNIVERSITY | $1,958,105 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of our program is to develop novel broad spectrum chemotherapeutics that can be used for Phase 1 clinical trials for treating the diseases caused by priority pathogens such as Francisella tularensis, Burkholderia pseudomallei and Yersin | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $2,365,512 | Grant | Trans-NIH Recovery Act Research Support: Orthopoxviruses (Smallpox, Monkeypox, etc.) have the potential for causing serious human health problems. Although Smallpox has been eradicated from the wild, it is feared that there may be rogue stockpiles that have the potential to be used as weapons o | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $838,896 | Grant | Trans-NIH Recovery Act Research Support: Influenza virus infections cause significant morbidity and mortality in the US and the world. Cytolytic CD8 T lymphocytes are critical for the control of respiratory viral infections, and their recruitment into tissues is essential for local immune and in | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $770,000 | Grant | Trans-NIH Recovery Act Research Support: Title: MODELING HIV- 1 SIRNA THERAPY The overall hypothesis to be tested in this proposal is that RNA interference can be developed as a therapeutic modality for HIV-1 disease. RNA interference is a highly evolutionary conserved cellular mechanism whereby | Health and Human Services, Department of / National Institutes of Health | 5/04/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $769,386 | Grant | Trans-NIH Recovery Act Research Support: This project will characterize the role of the ubiquitin ligase RNF5 in ER stress response in breast cancer and melanoma tumors, where its expression is elevated. Our preliminary results established a novel link between RNF5, ER stress and key phenotypes | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $9,296 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement (NOT-OD-09-060) for AREA grant research project Investigating the Role of Atgl in the Regulation of Glutamate Receptors. The research investigates a mutation that affects the number and placement of glutamate receptors at the syn | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| UNIVERSITY OF MARYLAND | $276,723 | Grant | Trans-NIH Recovery Act Research Support: We are submitting a One Year Competing Revision of R01 AG 16613 according to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. This competing revision supports a signific | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $126,125 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application is being submitted in response to Notice Number NOT-OD-09-058, entitled NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. For the supplement, we propose to add | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF KENTUCKY | $233,888 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision application is in response to NOT-OD-09-058 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.' We request competitive supplement to our NIH grant R21AG032567 entitled 'Role of p62 in Pro | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $524,371 | Grant | Trans-NIH Recovery Act Research Support: Alzheimer?s disease (AD) is characterized by a dominant component of inflammation, which in concert with enhanced amyloid production leads to secondary neuronal degeneration. Additionally, recent evidence also suggests a strong link between cerebrovascula | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MARYLAND | $90,804 | Grant | Trans-NIH Recovery Act Research Support: In our knowledge of the mechanism of sexual transmission of HIV-1 there is a very important gap. The population of HIV viruses soon after infection is, in most cases, monotypic; it is as if a single virus initiated infection. The population of viruses in | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $16,005 | Grant | Trans-NIH Recovery Act Research Support: Herpesvirus-encoded protein kinases (HPKs) have attracted increasing attention lately due to the growing evidence of their involvement in different aspects of the viral life cycle, making them appealing targets for antiviral therapy. The broad objectives | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| UNIVERSITY OF ARIZONA | $115,065 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is requested to provide salary and supplies for a talented post-doctoral student who will extend the analysis of human IL13 polymorphisms by generating and analyzing additional TG lines representing the Th2 locus-wide haplot | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $7,457 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funds I received were under call NOT-OD-09-60 Administrative Supplement Providing Summer Research Experiences for Students and Science Educators, to supplement my NIH R21 grant 1R21AI077907-01A1 from the NATIONAL INSTITUTE OF ALLERGY AND INFECTIO | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF ROCHESTER | $114,241 | Grant | Trans-NIH Recovery Act Research Support: On the parent R21 award, we have established a system of passively transferring protective anti- influenza nucleoprotein monoclonal antibodies into both B lymphocyte-deficient mice as well as normal mice. This is a significant step in allowing the Specifi | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WAKE FOREST UNIVERSITY | $294,958 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision of R21 AT004234-01 Effectiveness of Integral Yoga on Objective and Subjective Menopausal Hot Flashes is in response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Th | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| GEORGE MASON UNIVERSITY | $10,805 | Grant | Trans-NIH Recovery Act Research Support: Parent R21 Grant: Surrogate and Sentinal Technologies to Monitor Stability of Cancer Phosphoproteins The purpose of this ARRA supplement is | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $99,328 | Grant | Trans-NIH Recovery Act Research Support: ARRA award funds will carry out a pilot study where we will examine MCJ expression in tumor tissues of breast cancer patients. Since no previous published studies have examined MCJ in breast tumors the purpose of this Revision application is to find what | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $118,002 | Grant | Trans-NIH Recovery Act Research Support: This application is submitted in response to NIH Notice Number NOT-OD-09-058 entitled 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications'. Current techniques for full karyotype analysis rely on metaphase spreads, a | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $18,180 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to provide support for summer employment of two undergraduate research fellows who will work in a laboratory at the University of Montana COBRE Center for Structural and Functional Neuroscience. The summer fellowships will | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $204,149 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research proposal is to understand the nature of the interactions between sweet proteins and sweet taste receptor (STR). Recent chimera and mutagenesis studies show that both the Venus Flytrap Module (VFTM) and Cysteine Rich Domain (CRD) | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| NORTHWESTERN UNIVERSITY | $105,339 | Grant | Trans-NIH Recovery Act Research Support: We are conducting an experiment to examine how adults learn a grammar involving combining sounds of an artificial language. Grammar learning provides an advantage for investigating the interaction between genes and language acquisition because of the est | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,534 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Positional cloning has helped identify the molecular causes of many of Mendelian disorders. Genes involved in the more common forms of deafness and ataxia have been identified and are often clinically tested. However, | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $95,625 | Grant | Trans-NIH Recovery Act Research Support: Selection of odorant receptor (OR) and maintainence its expression in the olfactory sensory neuron (OSN) is not well understood. To investigate the mechanism of OR selection and maintenance, in the parent application we proposed to define OR sequence fra | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $13,763 | Grant | Trans-NIH Recovery Act Research Support: This grant was awarded as an Administrative Supplement under the parent grant entitled, Comprehensive transcriptome analysis for Porphyromonas gingivalis and has the same long term objectives.The parent grant aims to explore the use of a commercially avai | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER | $115,356 | Grant | Trans-NIH Recovery Act Research Support: This application for a Competitive Revision to the previously funded project, R21DE019414-01 is in response to NOT-OD-09-058 NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Candida albicans causes both mucosal a | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF UTAH, THE | $91,569 | Grant | Trans-NIH Recovery Act Research Support: Project Summary The association between the physical environment and the risk of being overweight or obese are difficult to estimate because residents are not randomly distributed by neighborhood. When neighborhood selection bias exists, estimates of the | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $40,125 | Grant | Trans-NIH Recovery Act Research Support: 1. The holographic recording material proposed on the parent grant proves to be too insensitive for practical application. We plan to explore a range of other holographic materials including near infrared (NIR) sensitive materials (InPhase Technologies, B | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $252,134 | Grant | Trans-NIH Recovery Act Research Support: The significant contribution of the Administrative Supplement would be to provide for the long-term hiring of a Research Assistant at UAB which will allow us to increase the rate at which we record using fMRI and electrophysiology in this study. This will | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $9,870 | Grant | Trans-NIH Recovery Act Research Support: Sexual dysfunction, including disorders of sexual desire, arousal, orgasm and sexual pain, affects approximately 40% of American women, often with significant consequences on quality of life. Despite the prevalence, the causes of female sexual dysfunction | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $11,980 | Grant | Trans-NIH Recovery Act Research Support: The broad, long-term objective of this study is to validate Measurement of Youth Media Exposure (MYME), a multimethod instrument designed to obtain a more sensitive and comprehensive assessment of adolescent use of and exposure to entertainment media. | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $80,584 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by the applicant) In women, one function most adversely affected by the age-related decrease in ovary reserve is decreased fecundity. The basis for this age-related change is the failure of dominant follicles to release eggs that can | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $68,917 | Grant | Trans-NIH Recovery Act Research Support: Myocardial infarction is a major cause of morbidity and mortality in the United States and most developed countries. Heart transplantation is an effective therapeutic modality in reconstituting the function of damaged heart. However, widespread applicatio | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $175,085 | Grant | Trans-NIH Recovery Act Research Support: Gene therapy has long been touted to hold the promise of cure for a variety of congenital diseases. However, gene therapy trials are still small in number and scale due to several problems that have prevented wider application of current technology. Ineff | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| KAISER FOUNDATION HOSPITALS | $99,971 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement would accelerate work on the two aims of the parent R21 grant: 1) Develop, evaluate, and make freely available an end-user natural language processing (NLP) development tool suite to facilitate rapid and effective developme | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| SAINT LOUIS UNIVERSITY | $32,140 | Grant | Trans-NIH Recovery Act Research Support: The study's aim is to develop a bedside assay to detect pulmonary micro-aspirations of gastric contents. Such a test is needed to differentiate between frequent and infrequent aspirators so that interventions can be planned accordingly. A total of 2,200 a | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $10,185 | Grant | Trans-NIH Recovery Act Research Support: Title: Regulation of Synapse Specificity in the Developing CNS. This award supports undergraduate research in the laboratory by providing them with paid employment during the summer and fall. Three undergraduate students will work on this project to gener | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| MIND RESEARCH NETWORK, THE | $507,037 | Grant | Trans-NIH Recovery Act Research Support: The aim of the current project is to utilize empirical electrophysiological data (magnetoencephalography; MEG and functional magnetic resonance imaging; FMRI) to inform a human model of the putative pathology underlying cognitive deficits and subsequent r | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ROCHESTER | $8,932 | Grant | Trans-NIH Recovery Act Research Support: This award is to support Summer Research Experiences for Students and Science Educators. It will focus on further characterizing the expression pattern of IFN- and TNF, by RT-PCR and qPCR. In parallel, we will also generate constructs to express IFN- and | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $249,713 | Grant | Trans-NIH Recovery Act Research Support: Herpesvirus latency and reactivation in macaque models of human disease -- The goal of the parent grant is to characterize the life cycle and biology of the two distinct lineages of macaque rhadinoviruses related to human herpesvirus 8 that are associat | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $150,120 | Grant | Trans-NIH Recovery Act Research Support: This project provides short-term experience and training in biomedical research for undergraduate students from underrepresented and disadvantaged groups. The Principal Investigator, Judith S. Bond, PhD, is an NIDDK funded investigator for more than 30 ye | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: There is a serious gap nationwide in the number of individuals whose training emphasizes global health issues. The number of professionals with firsthand experience in global health issues is critically low. The overall objective of the Case Framework Pro | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF MARYLAND | $113,100 | Grant | Trans-NIH Recovery Act Research Support: Macrophages are central to our innate immune responses to infection and malignancy. Bacterialproducts, such as Gram negative lipopolysaccharide (LPS), and cytokines, such as interferons (IFNs),program the expression of an array of pro- and anti-inflammato | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $22,848 | Grant | Trans-NIH Recovery Act Research Support: We seek to establish mechanisms for quite general processes, such as membrane fusion and perforation, as well as to lay the groundwork for discovering novel classes of antiviral therapeutics and for designing new vaccines. | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $189,000 | Grant | Trans-NIH Recovery Act Research Support: Molecular Genetic Analysis of Colorectal Cancer: Activation due to phospho-peptide binding To fully elucidate the activation mechanism of the oncogenic mutations of PI3K? we designed mutants at the interfaces of the SH2 domains (both nSH2 and cSH2) with t | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $99,435 | Grant | Trans-NIH Recovery Act Research Support: Cigarette smoking causes 30% of all cancer mortality in the developed world. Tobacco-specific nitrosamines, the subject of this proposal, are accepted causes of cancer in people who use tobacco products. The two most carcinogenic of these compounds- 4-(me | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WAKE FOREST UNIVERSITY | $100,001 | Grant | Trans-NIH Recovery Act Research Support: The metallochemistry and molecular biology of iron converge in the study of ferritin structure and function. Ferritin is an iron binding protein whose regulation, once thought to be responsive only to changes in cellular iron content, has | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF WASHINGTON | $95,823 | Grant | Trans-NIH Recovery Act Research Support: Accumulation and switches of laminin isoforms is a feature of glomerulonephropathy ) and aging kidney. In the current R37 funding we developed powerful strategies to study transcriptional expression of laminin genes in their native genomic environment. T | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $100,001 | Grant | Trans-NIH Recovery Act Research Support: The large?conductance Ca2+?sensitive potassium (BK) channel plays an important role in urinary bladder (UB) function, as evidenced by the fact that targeted disruption of the BK pore?forming ??subunit results in detrusor overactivity and urinary incontine | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $99,132 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Mechanisms of Mitotic Spindle Assembly and Function: Supplement Our goal is to discover how protein interactions between kinetochores and spindle microtubules function to achieve accurate chromosome segregation in mitosis and meiosis. Our work is | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $712,495 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the Hemodialysis Fistula Maturation Consortium (HFMC), a U01-funded partnership of NIDDK with six Clinical Centers (CCs) & a Data Coordinating Center (DCC), is to better understand the causes and consequences of arteriovenous fistula ( | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF UTAH, THE | $339,630 | Grant | Trans-NIH Recovery Act Research Support: Many arteriovenous fistulas (AVFs) suffer thrombosis or fail to mature and become usable. The Univ. of Utah will participate as a Clinical Center to conduct a prospective multi-center observational cohort study, investigating factors associated with the f | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MICHIGAN STATE UNIVERSITY | $469,999 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the two proposed Center Collaborative Research Projects is to fill specific gaps in our knowledge of the impact of in utero, early postnatal and pubertal environmental exposures on mammary gland development at the cellular, molecu | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $458,410 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): One critical need for the development of reliable docking and scoring (d/s) is a large dataset containing high quality experimental protein-ligand complex structures, together with accurate binding affinity data. An on | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $6,833,921 | Grant | Trans-NIH Recovery Act Research Support: HIV infection in the US occurs disproportionately among racial/ethnic minority youth in urban areas. The Adolescent Trials Network for HIV/AIDS Interventions (ATN) has developed a community-based primary HIV prevention infrastructure in 13 cities anchored | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $94,400 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Pelvic floor disorders, such as urinary incontinence, pelvic organ prolapse, and fecal incontinence, are common and significant health-related problems for women in the United States. Outcomes following surgical and no | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $1,511,274 | Grant | Trans-NIH Recovery Act Research Support: This Administrative Supplement will enable an extensive collection of valuable medical images obtained during clinical care to be discoverable by the scientific community for research by using the i2b2 framework to support queries for medical images in a | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $586,598 | Grant | Trans-NIH Recovery Act Research Support: The proposed Administrative Supplement for Collaborative Community Engagement Research will provide additional support to the NCRR-funded Indiana CTSI and 10 other collaborating CTSA centers and community partners to develop new resources that will advanc | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CINCINNATI | $559,637 | Grant | Trans-NIH Recovery Act Research Support: The vision of the University of Cincinnati Academic Health Center (AHC) Institutional CTSA is to create an environment to facilitate translating discoveries to clinical application. Our new academic home for clinical and translational research, the Center | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NORTHWESTERN UNIVERSITY | $312,980 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplement brings together three scientist from two institutions to develop new bianalytical tools and methods to understand the molecular changes that signal parasite devel | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $264,617 | Grant | Trans-NIH Recovery Act Research Support: Dosage compensation is a striking example of the interplay between gene-specific regulation and chromosomal architecture. This process has evolved to make X-linked gene expression equivalent in males with one X chromosome and females with two. In species | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF WASHINGTON | $453,434 | Grant | Trans-NIH Recovery Act Research Support: Resolution of the genetic and environmental components of a disease trait is an important step in developing methods for prevention and treatment.Identification of genes through family-based designs has increased understanding of the biology underlying ma | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| STOWERS INSTITUTE FOR MEDICAL RESEARCH | $579,026 | Grant | Trans-NIH Recovery Act Research Support: A protein complex named Saga, is located in every cell of the human body. It is a major regulator of gene transcription and is implicated in the development of several forms of cancers and neurodegenerative diseases. To understand the role of this protei | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $284,087 | Grant | Trans-NIH Recovery Act Research Support: As described in the parent proposal, RNA dynamics and conformational transitions are unbiquitous in RNAmediated cellular events and processes such as pre-mRNA splicing, translation, and RNA catalysis/self-splicing. Within this context, P1 duplex docking i | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CONNECTICUT | $50,084 | Grant | Trans-NIH Recovery Act Research Support: This award will purchase microscope image acquisition and processing equipment that is essential for the studies that use fluorescence image analysis to study bacterial cell cycle events and the structure and function of the bacterial cytoskeleton. This | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $76,284 | Grant | Trans-NIH Recovery Act Research Support: THE DEVELOPMENT OF SUSTAINED ATTENTION IN INFANTS The objectives are to study the development of sustained attention in young infants and to relate development in sustained attention to concurrent heart rate (HR) changes and brain activity (EEG, ERP). The | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| BAYLOR COLLEGE OF MEDICINE | $136,000 | Grant | Trans-NIH Recovery Act Research Support: This application is a request for an administrative supplement from the American Recovery and Reinvestment Act of 2009 (announcement NOT-OD-09-056) for our parent grant, HD33438, G?Analysis of Reproductive Function Using Transgenic MiceG?. Our parent gra | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $77,674 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this work is to understand how the motor cortex constructs movement plans and implements them as actions. Previous work in this project demonstrated that neural population activity in the macaque monkey primary motor cortex (MI) corte | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $229,600 | Grant | Trans-NIH Recovery Act Research Support: Our work addresses the functions and mechanisms of long-range growth factor signaling in vivo and in vitro. The title of our work is: The control of synapse assembly by target-derived Nerve Growth Factor (NGF). The overall purpose of this project is to un | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| INTELLIGENT SUBSTRATES, INC. | $96,755 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to develop new technology that will allow rapid user- defined patterning of proteins on cell culture substrates at dimensions ranging from 50 nanometers to millimeters. Patterned cell culture substrates are emerging a | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HUMMINGBIRD SCIENTIFIC, LLC | $271,908 | Grant | Trans-NIH Recovery Act Research Support: Transmission electron microscope (TEM) tomography provides three-dimensional images at the nanometer scale. It is a mainstream technique in biological electron microscopy, and is rapidly finding applications in the semiconductor and nanotechnology industr | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| OREGON CENTER FOR APPLIED SCIENCE, INC | $139,508 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the AARA funding is to enhance the randomized evaluation of a Internet program to train Nursing Assistants (NAs) in long term care facilities (LTCs). Participants will learn to prevent aggressive behaviors by residents, or if necessa | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FAIRWAY MEDICAL TECHNOLOGIES, INC. | $199,998 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Optoacoustic imaging enhanced by gold nanorods Supplemental funding will accelerate the development and market potential for a laser optoacoustic imaging system with enhanced sensitivity and resolution that uses a novel optoacoustic contras | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| INCOGEN INC | $392,746 | Grant | Trans-NIH Recovery Act Research Support: Title: Visual Programming Tool for Integrated Gene/Protein Networks in Cancer Research. Under the parent award, the team is developing a software tool that will allow multidisciplinary teams of researchers to meaningfully integrate knowledge about genes a | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| COMPENDIA BIOSCIENCE, INC. | $263,987 | Grant | Trans-NIH Recovery Act Research Support: Development of Oncomine Professional as a Platform for Biopharmaceutical Research (Supplement): DNA microarray studies, largely sponsored by the NIH and other granting agencies, have generated a wealth of data uncovering the complex gene expression patter | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ORTHOGEN LLC | $192,278 | Grant | Trans-NIH Recovery Act Research Support: The aim of this research is to develop an improved, synthetic bone graft material for use in dentistry. The loss of teeth is often accompanied by the loss of jaw bone. Restoring this lost bone is often a prerequisite for the installation of dental implant | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| AEROSOL DYNAMICS INC. | $267,616 | Grant | Trans-NIH Recovery Act Research Support: For this research project we developed a new method for concentrating submicrometer and ultrafine airborne particles, which has application to characterization for environmental health studies. The project used PhD and BS scientists and engineers in our f | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| QUANTUMBIO, INC | $99,940 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The current state of the art of in silico drug discovery relies almost exclusively on molecular mechanics force fields, such as AMBER, and empirical potentials. It is well known that while these approaches are excellen | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WISTAR INSTITUTE OF ANATOMY & BIOLOGY (INC) | $418,250 | Grant | Trans-NIH Recovery Act Research Support: Human cytomegalovirus (HCMV) infection has serious consequences for immunocompromised individuals, such as AIDS and organ transplant patients and congenitally infected newborns. Of symptomatic newborns, 12% die and many of the survivors suffer mental reta | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| HEALTH RESEARCH, INC. | $491,634 | Grant | Trans-NIH Recovery Act Research Support: To obtain a detailed understanding of both innate and adaptive immune responses to bacterial pathogens that cause repeated respiratory tract infections in chronic obstructive pulmonary disease (COPD) patients. We are studying how key outer membrane antige | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $300,000 | Grant | Trans-NIH Recovery Act Research Support: Respiratory synctial virus (RSV) is a major cause of often serious, life-threatening lung disease in infants and young children, immunosuppressed organ transplant recipients, patients suffering from cystic fibrosis, congenital heart disease, and the elder | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $374,137 | Grant | Trans-NIH Recovery Act Research Support: Abstract An exciting development in the innate immunity field is the discovery that macrophages enlist autophagy to protect their cytoplasm from infection. Nutrient deprivation has long been known to induce autophagy, but how infection rapidly triggers th | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF ILLINOIS | $500,000 | Grant | Trans-NIH Recovery Act Research Support: In the parent grant, we proposed to 1) Determine the ability of human PTH (hPTH) to mitigate or prevent radiation-induced thrombocytopenia in response to a radiation dose resulting in 30% lethality by 30 days (LD30/30) or 95% lethality by 30 days (LD95/30 | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $186,648 | Grant | Trans-NIH Recovery Act Research Support: As specified in our application, the purpose of the administrative supplement is: 1. Keep our GI radioprotection team together as we continue to submit related proposals, pursue other funding opportunities, and mentor new students. a. Provide research op | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF ROCHESTER | $270,220 | Grant | Trans-NIH Recovery Act Research Support: With the scientific progression, we found that the radiation-induced alteration of electrolyte transportation could be reversed towards normal as evidenced by the Ussing Chamber assay. The supplemental money allowed us to facilitate this part of study by | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WINIFRED MASTERSON BURKE MEDICAL RESEARCH INSTITUTE, INC., THE | $271,827 | Grant | Trans-NIH Recovery Act Research Support: Stroke induces infiltration of peripheral immune cells into infarct territory and thus exposes blood/serum components to the brain. Because CD36, an inflammatory mediator that contributes to stroke-induced injury, is expressed in peripheral organs/cells, | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| FLORIDA INTERNATIONAL UNIVERSITY | $261,618 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of our project funded by the Recovery Act is to structurally and functionally analyze the small nuclear RNA (snRNA) variants in humans. Our supplemental proposal aims to examine the assembly into splicesomes and the splicing capacity | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| UNIVERSITY OF PUERTO RICO | $164,045 | Grant | Trans-NIH Recovery Act Research Support: The capability to regenerate lost or damaged organs is severely limited in humans and most vertebrate animals. Other animals, in contrast, have remarkable regenerating abilities. Among these are the echinoderms, a group of animals closely related to verte | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF TEXAS AT BROWNSVILLE | $222,076 | Grant | Trans-NIH Recovery Act Research Support: This project will provide critical information on the mechanisms leading to different forms of epilepsy, a devastating and very common neurological disorder. This project seeks to tackle problems related to the neurotransmitter release machinery within th | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| BARRY UNIVERSITY, INC. | $49,000 | Grant | Trans-NIH Recovery Act Research Support: Pif1P's Regulation and Role in Telomere End Protection in S. cerevisiae | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS AT EL PASO | $99,225 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to request funding to increase the tempo of research of the parent SCORE SC2 project titled ''Characteristics of Metabolically Obese but Normal-weight Hispanic Women which was funded by NIGMS and NIDDK. The | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| UNIVERSITY CORPORATION, THE | $60,152 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this project is to develop an environmentally friendly method for the preparation of 2-deoxy-C-aryl glycosides, a family of natural products which demonstrate important biological properties such as antitumor, antibiotic and ant | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| RFCUNY - LEHMAN COLLEGE | $134,823 | Grant | Trans-NIH Recovery Act Research Support: Individual investigator-initiated research projects for faculty at MSIs to conduct research of limited scope in environments with limited research infrastructure/facilities. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| BENEDICT COLLEGE, THE | $216,016 | Grant | Trans-NIH Recovery Act Research Support: Project Title: ' Identification of transamidated proteins involved in cell death induction.' 1) Administrative supplements as proposed in this award will accelerate the rate of scientific research.. Employing a new lab technician to purify cross-linked p | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ARIZONA | $101,302 | Grant | Trans-NIH Recovery Act Research Support: The goal of this training grant continues to be the training of pre and post-doctoral students in the discipline of cancer biology research so that they can participate in finding solutions to the problems associated with human cancer. The approach to thi | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $40,743 | Grant | Trans-NIH Recovery Act Research Support: Predoctoral Training in Pharmacological Sciences This predoctoral training program is dedicated to training outstanding scientists in the pharmacological sciences. A highly productive and well-funded faculty provide a broad diversity of research areas fo | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $47,373 | Grant | Trans-NIH Recovery Act Research Support: This competitive grant renewal requests a continuation of support for years 26-30 for some of the predoctoral students in the Brown University Graduate Program in Molecular Biology, Cell Biology and Biochemistry (MCB). Students are admitted to this interd | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $128,084 | Grant | Trans-NIH Recovery Act Research Support: Multidisciplinary research at the Chemistry:Biology interface has expanded so rapidly in the past few decades that such cross-training is now crucial for the development of the next generation of chemists and biologists. The objectives of the proposed tra | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $85,398 | Grant | Trans-NIH Recovery Act Research Support: The goal of the Medical Scientist Training Program (MSTP) is to train students in clinical medicine as biomedical research scientists. Training is offered in a diverse number of medically related scientific areas. This is accomplished by means of a fle | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $41,236 | Grant | Trans-NIH Recovery Act Research Support: We seek one additional training slot for the Biotechnology Training Program (BTP) at UVa. In the first nine (9) years of funding, we built the BTP into a highly interactive community of Ph.D. trainees drawn selectively from an annual spring competition o | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $87,028 | Grant | Trans-NIH Recovery Act Research Support: One student has been appointed to the training grant due to ARRA funds. A second student will be appointed effective July 1, 2010. This will complete the training funded by ARRA. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF IOWA, THE | $205,020 | Grant | Trans-NIH Recovery Act Research Support: The goal of this training program is to train biostatisticians to take a leadership role in developing new interdisciplinary scientific research. This will be achieved by providing rigorous training in the disciplines of statistics and microbiology, and a | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $48,172 | Grant | Trans-NIH Recovery Act Research Support: The goal of the Minority Access to Research Careers Undergraduate Student Training in Academic Research (MARC U*STAR) Program at the University of Maryland, Baltimore County (UMBC) is to increase the number of scientists with terminal degrees from underre | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY | $329,560 | Grant | Trans-NIH Recovery Act Research Support: ARRA Supplement for the NC A & T MARC U STAR Grant. The purpose of this supplement is to intensify our efforts to increase the number of minority students at NC A & T who will pursue research training and careers in biomedical research. Funding Actions: | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF PITTSBURGH THE | $901,232 | Grant | Trans-NIH Recovery Act Research Support: The proportion of persons living with HIV/AIDS who are over 50 rose to 22.5% of all cases in 2004, and with the increasing use of Highly Active Antiretroviral Therapy (HAART), more than nearly three-quarters of HIV-infected individuals over 50 now die fro | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $3,922,722 | Grant | Trans-NIH Recovery Act Research Support: The Centers for Innovative Research to Control AIDS (CIRCA) Clinical Trial Unit (CTU) at Columbia University Mailman School of Public Health (MSPH) was established to conduct HIV prevention studies in New York City and New Jersey and to focus on underrepr | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| FENWAY COMMUNITY HEALTH CENTER, INC. | $2,472,041 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the administrative support supplement is to support the work of HPTN 061 by providing research infrastructure. The purpose of this study is to determine the feasibility and acceptability of a multifaceted intervention among Black men who ha | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| PUBLIC HEALTH FOUNDATION ENTERPRISES, INC. | $2,521,856 | Grant | Trans-NIH Recovery Act Research Support: The San Francisco Vaccine and Prevention Unit (SFVPU) provides scientific leadership, capacity to recruit study volunteers into vaccine and non-vaccine prevention trials, innovative methods for community engagement in research, and mentorship of junior in | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WASHINGTON UNIVERSITY, THE | $977,544 | Grant | Trans-NIH Recovery Act Research Support: This proposal includes two components to increase the pace of discovery in our project titled 'Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation' (1U01AI077810-01), address the economic stimulus priorities, and provide repo | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| WAYNE STATE UNIVERSITY (INC) | $853,019 | Grant | Trans-NIH Recovery Act Research Support: Correlative studies for a Phas I Dose Escalation Study of the Sonic Hedgehog Smoothened Antagonist GDC-0449 (NSC # 747691) Plus Pan-Notch Inhibitor RO4929097 (NCS # 749225) Administered in Patients with Breast Cancer. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $1,095,375 | Grant | Trans-NIH Recovery Act Research Support: This proposal responds to RFA-CA-07-505 'The American College of Radiology Imaging Network' and addresses the needs of ACRIN's Biostatistics and Data Management Center (BDMC). This proposal is submitted in coordination with a proposal from the Headquarter | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $482,434 | Grant | Trans-NIH Recovery Act Research Support: To date, one must conclude that the pace of progress in disease control and preservation of functional integrity and quality of life for pediatric brain tumors remains below that of most other major types of childhood cancers. Recent advances in cellular | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| DREXEL UNIVERSITY | $167,925 | Grant | Trans-NIH Recovery Act Research Support: This is a request to supplement our parent award, which is to discover and develop biomarkers for the early detection of liver cancer and hepatitis, with funds from American Recovery and Reinvestment Act as in NOT-OD-09-056. In the parent grant progress, | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| NATIONAL CHILDHOOD CANCER FOUNDATION | $1,405,307 | Grant | Trans-NIH Recovery Act Research Support: This supplement award supports Accelerating Clinical Trials of Novel Oncologic Path Ways (ACT NOW) program for Protocol ADVL0911, which is a Phase I Dose Escalation Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Relapsed/ | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $297,519 | Grant | Trans-NIH Recovery Act Research Support: Principal Investigator/Program Director (Last, first, middle): Miller, Josef, M. RESEARCH & RELATED Other Project Information 1. * Are Human Subjects Involved? l Yes m No 1.a. If YES to Human Subjects Is the IRB review Pending? l Yes m No IRB Approval Dat | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $107,964 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to an intensi | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| WAKE FOREST UNIVERSITY | $155,882 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is a multi-center randomized clinical trial to determine the long-term impact of weight loss on cardiovascular morbidity and mortality in over 5000 overweight individuals with type 2 diabetes. Participants were randomly assigned to an intensiv | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $235,366 | Grant | Trans-NIH Recovery Act Research Support: Acute liver failure is a rare but devastating disease that has been studied for 11 years by our established consortium of 23 academic centers. We now propose an administrative supplement to support more intensive management of all aspects of the data and | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ILLINOIS | $152,186 | Grant | Trans-NIH Recovery Act Research Support: These supplemental funds are being used to improve both event ascertainment collection and retention efforts at the University of Illinois at Chicago (UIC) Chronic Renal Insufficiency Cohort (CRIC) Study Clinical Center. UIC has enrolled 521 participants | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $329,400 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of this Administrative Supplement proposal is to provide funding for study coordinator salary support at CKiD participating sites. The ability to secure the dedicated time of coordinators well trained in carrying out the CKiD protocol is c | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| THE VANDERBILT UNIVERSITY | $2,595,935 | Grant | Trans-NIH Recovery Act Research Support: The NIDDK provides funding to four different basic science consortia. Each of these groups has established an informatics infrastructure, but has done so independently. This poses major limitations for the NIDDK since there is no direct way for visitors | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| DM-STAT, INC | $82,081 | Grant | Trans-NIH Recovery Act Research Support: DM-STAT serves as the Data Coordinating Center (DCC) for the Collaborative Programs of Excellence in Autism (CPEA)/Studies to Advance Autism Research and Treatment(STAART) Networks. The DCC intends to perform the analysis of the primary S002 (Fluoxetine | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| PORTLAND STATE UNIVERSITY | $301,026 | Grant | Trans-NIH Recovery Act Research Support: Although the prevalence of family-friendly policies in US workplaces has increased dramatically in recent years, few have been studied using scientifically sound designs. To address this critical gap, the NIH and the CDC formed the Work, Family, and Healt | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| BAYLOR COLLEGE OF MEDICINE | $45,117 | Grant | Trans-NIH Recovery Act Research Support: This application is a request for an administrative supplement for our parent grant, U01 HD060496, G?Identification of Small Molecule Contraceptives that Target the Male GermlineG? from the Eunice Kennedy Shriver National Institutes of Child Health and Hu | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $783,397 | Grant | Trans-NIH Recovery Act Research Support: The generation of complete or nearly complete eukaryotic genome sequences has produced an explosion of insights into the coding potential and evolution of genomes. However, we have less information about how key processes involving DMA are regulated, incl | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $166,257 | Grant | Trans-NIH Recovery Act Research Support: Our modENCODE parent grant U01-HG004261 is aimed at annotating the functional short regulatory RNAs of Drosophila melanogaster using deep sequencing methodology. These include known classes of Argonaute-bound RNA such as microRNAs, small interfering RNAs, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $638,051 | Grant | Trans-NIH Recovery Act Research Support: The C. elegans transcriptome group of the modENCODE project has applied second-generation sequencing of cDNAs from a variety of worm stages, sexes and growth conditions to greatly improve the annotation of the C. elegans genome. With supplemental funding | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $1,457,800 | Grant | Trans-NIH Recovery Act Research Support: Scope of the overall project and anticipated contribution of the requested supplement: Scope of parent grant: The discovery of putative causal (genuine) genetic variants associated with complex diseases and traits, such as cardiovascular diseases, cancer, | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| THE VANDERBILT UNIVERSITY | $331,010 | Grant | Trans-NIH Recovery Act Research Support: The parent grant titled Epidemiologic Architecture for Genes Linked to Environment (EAGLE) is funded to use DNA samples from the National Health and Nutrition Examination Surveys for characterizing genetic variations identified through genome-wide associa | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| EMORY UNIVERSITY | $223,748 | Grant | Trans-NIH Recovery Act Research Support: Project iMPPACS provides the first large-scale test of a culturally targeted TV and radio campaign to reduce HIV-associated sexual risk behavior among 1,600 African-American teens in four mid-sized cities in the U.S. Initial findings offer evidence of pro | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $366,250 | Grant | Trans-NIH Recovery Act Research Support: The overarching aims of the REGARDS project are to advance the understanding of the causes for the excess stroke mortality among residents of the Southeastern Stroke Belt (SB) and among African Americans (AA) regardless of residence. To accomplish these a | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $1,050,843 | Grant | Trans-NIH Recovery Act Research Support: Inflammation is a process essential for host defense and tissue repair. However, exuberant defense may cause pathogenic changes leading to vascular diseases such as atherosclerosis. This is because multiple cytokines are involved in the process and each c | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $324,683 | Grant | Trans-NIH Recovery Act Research Support: The main objective of this grant to provide support for the integration, standardization, and coordination of standardized information-technology (IT) tools and operational procedures for the Radiation Therapy Oncology Group (RTOG). Specifically we inten | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| GYNECOLOGIC ONCOLOGY GROUP , THE | $678,418 | Grant | Trans-NIH Recovery Act Research Support: The Gynecologic Oncology Group (GOG) is the foremost multidisciplinary cooperative clinical trial research group devoted to the study of gynecologic malignancies. Since its inception in 1970, the GOG has been a recognized leader in the development of new | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $331,199 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): There has been a long standing research and clinical collaboration between Urology and Reproductive Endocrinology at the University of Michigan. This proposal describes the qualifications and experience of the Reproduc | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $185,839 | Grant | Trans-NIH Recovery Act Research Support: This project represents a Recovery Act Administrative Supplement for parent grant 1U10HD055942-01: ?Letrozole Therapy for IVF/ET: Effects on Multiple Pregnancy and Treatment Burden?. The parent grant established the University of Texas Health Science Cent | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ROCHESTER | $1,290,000 | Grant | Trans-NIH Recovery Act Research Support: This project would entail expanding the current 12-color panels we have in two ways: 1) to create new 12-color panels that in addition to 6-8 anchor markers that recognize the main populations also incorporate markers of activation, inhibition/exhaustion | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MEHARRY MEDICAL COLLEGE | $1,358,297 | Grant | Trans-NIH Recovery Act Research Support: This supplement to Meharry Medical College's cancer research center grant provides support to hire a physician scientist such as a surgical oncologist with experience in breast, prostate, or colon cancer research. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $61,030 | Grant | Trans-NIH Recovery Act Research Support: The Philippine Mollusk Symbiont ICBG (PMS ICBG) project links a biodiversity survey of marine mollusks in one of the world's hotspots of diversity, with drug discovery and enzyme bioprospecting aimed at bacterial symbionts of mollusks. Mollusks constitute | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| FRONTIER SCIENCE & TECHNOLOGY RESEARCH FOUNDATION, INC. | $797,350 | Grant | Trans-NIH Recovery Act Research Support: The E4508 randomized phase II clinical trial will evaluate the combination of chemotherapy with EGFR inhibition, IGF-1R inhibition or both. Although the clinical study accrual rate is estimated at 12 months, there will be an interim toxicity analysis requ | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| GYNECOLOGIC ONCOLOGY GROUP , THE | $143,341 | Grant | Trans-NIH Recovery Act Research Support: The Gynecologic Oncology Group (GOG) is the foremost multidisciplinary cooperative clinical trial research group devoted to the study of gynecologic malignancies. Since its inception in 1970, the GOG has been a recognized leader in the development of new | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $689,999 | Grant | Trans-NIH Recovery Act Research Support: The Southwest Oncology Group is an adult, multi-disease, multi-modality clinical cancer research organization with 35 Member Institutions, 29 Community Clinical Oncology Program (CCOP) institutions, including 7 Minority-Based CCOPs, 27 Urologic Cancer Out | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRINITY HEALTH CORPORATION | $199,900 | Grant | Trans-NIH Recovery Act Research Support: This award is designed to fund a research nurse navigator program with the goal of accelerating the tempo of scientific research by increasing registration and patient recruitment to national cooperative group research trials and allow for job creation f | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $433,381 | Grant | Trans-NIH Recovery Act Research Support: The Studies of the Ocular Complications of AIDS Research Group is dedicated to understanding and improving the outcomes of the ocular complications of AIDS. The Longitudinal Study of the Ocular Complications of AIDS (LSOCA) is a prospective cohort study o | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $67,340 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative Observational Study of Myopia in COMET Children (COSMICC) is a longitudinal study that has followed the cohort of children who participated in the Correction of Myopia Evaluation Trial (COMET. Currently, at an average age of 17 years, my | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF ROCHESTER | $700,000 | Grant | Trans-NIH Recovery Act Research Support: This grant application is a companion to the application submitted by Dr. Mark Kupersmith for the Neuro-Ophthalmology Research Disease Investigator Consortium (NORDIC). This application describes a Data Coordination and Biostatistics Center (DCBC), a Vis | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| DUKE UNIVERSITY | $246,619 | Grant | Trans-NIH Recovery Act Research Support: The North Carolina Collaborative Pediatric Pharmacology Research Unit (NCC-PPRU) will be composed of personnel from Duke University and the University Of North Carolina (UNC). The NCC-PPRU will help develop new medications with pediatric indications and i | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF UTAH, THE | $234,002 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Pelvic floor disorders are common, bothersome, and inadequately treated. The overarching aim of the investigators from the proposed University of Utah Pelvic Floor Disorders Clinical Site is to improve women's health i | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $252,370 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The objectives and aims of this application are for San Diego to become the first western United States clinical site in the Pelvic Floor Disorders Network (PFDN). The San Diego Clinical Site is a collaboration of thr | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| EMORY UNIVERSITY | $1,280,745 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of our current U19 grant is to understand how a successful vaccine, the live yellow fever virus (YFV-17D) vaccine, induces long-term immunological memory and protective immunity in humans. The YFV-17D vaccine is recommended by the Centers | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $770,000 | Grant | Trans-NIH Recovery Act Research Support: Our primary objective is to obtain further information about the mechanisms of acute episodes of asthma both in adults and children. This requires knowing details of the patients, including exhaled nitric oxide (FeNO), exhaled breath pH, eosinophilia, and | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $472,516 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks a renewal of funding for the United States based International Breast Cancer Study Group (IBCSG) Statistical and Data Management Center, a resource that contributes to International-US collaboration in the following areas: Access to t | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BROAD INSTITUTE, INC., THE | $399,902 | Grant | Trans-NIH Recovery Act Research Support: New, sensitive and specific diagnostic and prognostic tests for early detection of cancer are desparately needed. This award aims to significantly expand the number of novel cancer-related assays that our project will develop. A second component of this p | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $363,974 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objectives are to continue to provide outstanding phenotyping services to the scientific community, provide a resource of expertise and knowledge for consulting on research projects, and encourage the collaboration among researchers across t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $95,000 | Grant | Trans-NIH Recovery Act Research Support: National Center for Canine Models of Duchene Muscular Dystrophy ARRA This administrative supplement of $95,000 will allow purchase of equipment to support our grant, 1 U24 NS059696-01A1, which established the National Center for Canine Models of DMD (NC | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $994,984 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We propose establishing the UCSC ENCODE Data Coordination Center to collect, organize, store, and provide access to data from the ENCODE project and other related projects, based on the well-established UCSC Genome Bro | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $3,853,630 | Grant | Trans-NIH Recovery Act Research Support: Pacific-Southwest Regional Center of Excellence for Biodefense and Emerging Diseases (the Center) is a research consortium comprising 28 projects clustered within six programs. The Center also features five core facilities that serve the entire region. Al | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $151,664 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to: 1. To employ a CHE (one of two, based at each partner institution) to increase the LlU/CU U54 Partnership's cancer education and outreach efforts to our communities and to train community health workers (CHWs) about: | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $500,000 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award provides funds to support project 2 and to accelerate the tempo of the parent grant. There are two specific tasks: Task 1: Systematically study and optimize the circulation lifetime of drug delivery motherships and nanoparticle pay | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTHWESTERN UNIVERSITY | $220,679 | Grant | Trans-NIH Recovery Act Research Support: The Goal of this supplement will be to adding both personnel and equipment.It will aid in increasing output by reducing the time spent on complex procedures and increasing experimental yield. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. | $342,766 | Grant | Trans-NIH Recovery Act Research Support: This is a partial award for the consortium with the Hugo W. Moser Research Institute at Kennedy Krieger effective 9/30/09. These supplemental funds are intended to accelerate the pace of biomarker discovery for FSHD therapeutics and will be targeted spec | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MARYLAND | $27,000 | Grant | Trans-NIH Recovery Act Research Support: This is a revised U56 application to the National Cancer Institute to support the planning and development of a Comprehensive Minority Institution and Cancer Center Partnership between the University of Maryland Eastern Shore (UMES--a minority serving ins | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $499,067 | Grant | Trans-NIH Recovery Act Research Support: The goals of this supplemental award are to enhance the research workforce development and dissemination activities of the University of California Davis (UCD) Clinical and Translational Science Center (CTSC) and to enhance use of workforce resources deve | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| MAYO CLINIC | $299,998 | Grant | Trans-NIH Recovery Act Research Support: The CTSA Consortium Strategic Goal #1 seeks to improve clinical and translational research management capability. The administrative and regulatory infrastructure supporting clinical research is often a key determinant of the success of funding applicatio | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $599,968 | Grant | Trans-NIH Recovery Act Research Support: The 'Utilization of Principles of Community-Based Participator Research (CBPR) and Concept Mapping to Foster and Inform Community Engaged Research' project is an important initiative that will further increase awareness about the community based participa | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| THE VANDERBILT UNIVERSITY | $553,019 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative to Build Community Capacity for Research is a joint project of Vanderbilt University Medical Center, Meharry Medical College, and Tennessee State University which proposes to create sustainable mechanisms and processes to develop and enh | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WASHINGTON UNIVERSITY, THE | $594,620 | Grant | Trans-NIH Recovery Act Research Support: This is a collaborative community engagement ARRA supplement request. There are over 80,000 clinical trials conducted each year in the US, and yet, less than 1 percent of the population participates in them. The so-called ?leaky pipe of clinical trial par | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WASHINGTON UNIVERSITY, THE | $998,312 | Grant | Trans-NIH Recovery Act Research Support: While the Washington University Institute of Clinical and Translational Sciences (ICTS) has made significant progress in deploying comprehensive resources to facilitate research, the ICTS is still hampered by inefficient communication and coordination ac | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $594,218 | Grant | Trans-NIH Recovery Act Research Support: TThe Hunter School of Nursing, City University of New York (HCSON) is an active partner of the Weill Cornell Medical Center Clinical and Translational Science Center (CTSC), a cluster of institutions forming a unique and cohesive biomedical complex on Man | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CHICAGO, THE | $282,714 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our community to determine the molecular underpinnings of disease or disease predisposition in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WASHINGTON | $596,069 | Grant | Trans-NIH Recovery Act Research Support: The University of Washington, the ITHS' home institution, serves as the medical school for five states -- Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI), providing the ITHS with enormous potential for collaboration and development of translationa | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $731,588 | Grant | Trans-NIH Recovery Act Research Support: The vitamin D receptor (VDR) is a transcription factor that mediates the actions of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) in the nucleus of target cells. The receptor binds in a cell-specific manner to target genes and regulates their transcriptional out | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $611,100 | Grant | Trans-NIH Recovery Act Research Support: Angiogenesis, the growth of new blood vessels, promotes tumor growth and metastasis. During the previous grant cycle, we found that the fibronectin receptor integrin a4_1 promotes tumor angiogenesis by distinct endothelial cell- and myeloid cell-mediated | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CONNECTICUT | $480,550 | Grant | Trans-NIH Recovery Act Research Support: The proposed research is designed to develop a novel way to engage killer T cells and helper T cells (two important players in the immune system) to work in a collaborative and synergistic manner so as to orchestrate a robust and long-lived cellular immun | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $656,944 | Grant | Trans-NIH Recovery Act Research Support: Cancer is caused by the activation of oncogenes and the inactivation of tumor suppressor genes. The targeted inactivation and repair of these gene products may be a specific and effective therapy for cancer. Previously, we have shown that the inactivation | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $554,976 | Grant | Trans-NIH Recovery Act Research Support: Environmental and endogenous exposure to chemicals that produce DNA-protein and DNA-peptide crosslinks are correlated with an increased risk of several cancers, asthma, and other diseases. Currently many thousands of individuals in the US population are e | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $705,281 | Grant | Trans-NIH Recovery Act Research Support: The psychoactive component of marijuana, ??9-tetrahydrocannabinol, binds to and activates cell surface receptors called cannabinoid receptors. Activation of these receptors produces intense responses in humans, which suggest that endogenous cannabinoid (e | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| JOHN WAYNE CANCER INSTITUTE | $14,359,357 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award was to fund the conduct of an in-progress research study. The purpose of the research study is to find out if melanoma can be treated by removing only a few lymph nodes (called ?sentinel nodes?) from a lymph basin (calle | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| YALE UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Recent progress in podocyte biology suggests that glomerular capsular cell, namely glomerular parietal cells have the potential to contribute to podocyte regeneration/renal repair after kidney development concludes. My results derived from projects suppor | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $107,406 | Grant | Trans-NIH Recovery Act Research Support: Administrative supplement to parent grant: Genome-wide promoter methylation profiling of glioma Since the beginning of the award in 9/1/2008 for the parent K-award entitled Genome-wide promoter methylation profiling of glioma, progress has been substant | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| WHITEHEAD INSTITUTE FOR BIO-MEDICAL RESEARCH | $556,963 | Grant | Trans-NIH Recovery Act Research Support: BRCA1 mutations trigger high penetrance breast carcinogenesis. Most such tumors are triple negative/basal-like. How loss of BRCA1 function elicits breast cancer development and why it does so at markedly high rates and, often, at abnormally young ages is | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $115,500 | Grant | Trans-NIH Recovery Act Research Support: Title: Induced pluripotent stem cell differentiation along neuronal, germ cell, and hematopoietic lineages. This supplemental funding was requested to accelerate the pace of research towards eventual clinical use of stem cell lines by providing additiona | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NEBRASKA | $398,855 | Grant | Trans-NIH Recovery Act Research Support: The Nebraska Research Network in Functional Genomics has two major components, the undergraduate campuses located throughout the State and the research campuses located in Omaha and Lincoln. On the undergraduate campuses, INBRE will support 24 faculty dir | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $45,095 | Grant | Trans-NIH Recovery Act Research Support: This fund is an ARRA administrative supplement to Fund #50437N entitled, 'Behavioral and MRI Evaluation of Prenatal Alcohol Exposure.' The supplement will provide support for an undergraduate college student who will support the research efforts of the pa | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $167,674 | Grant | Trans-NIH Recovery Act Research Support: Mechanisms of GABA-A receptor plasticity in alcoholism Alcohol abuse represents a significant problem in our society. Chronic intermittent ethanol (CIE) treatment of rats (60 doses of intermittent intoxication and withdrawal), encompasses all of the major | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $153,542 | Grant | Trans-NIH Recovery Act Research Support: Supplement-Arkansas Cancer Community Network (AR-CCN) Patient Navigators for the Cancer Care Continuum. The purpose of this application is to expand an existing Patient Navigation Program to address a critical disconnect between incidence and mortality fo | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| YALE UNIVERSITY | $7,565,277 | Grant | Trans-NIH Recovery Act Research Support: On behalf of the Reproductive Medicine Network (RMN), we, as the Data Coordination Center, submit this request in response to NIH announcement NOT-OD-09-056 for a Recovery Act administrative supplement. We will use the supplement to field a comparative ef | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CINCINNATI | $785,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this grant proposal is to use newly developed transgenic mouse models to 1) elucidate the role of keratocan-expressing cell lineage in corneal morphogenesis during development and in the maintenance of corneal stromal homeostasis in adult and | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF LOUISVILLE | $1,193,397 | Grant | Trans-NIH Recovery Act Research Support: Endothelial cells (ECs) are among the first cells to die acutely after contusive spinal cord injury (SCI), triggering secondary degeneration, including axon and myelin loss. We showed that i.v. treatments with the Tie2 ligand angiopoietin-1 (Ang1) plus t | Health and Human Services, Department of / National Institutes of Health | 7/28/2009 |
| UNIVERSITY OF NEW MEXICO | $755,839 | Grant | Trans-NIH Recovery Act Research Support: Ischemic injury to the deep white matter is frequently seen in patients with vascular cognitive impairment (VCI). Brain tissue from patients with VCI has matrix metalloproteinases (MMPs) in regions of myelin loss. VCI patients have increased MMPs in the c | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF KENTUCKY | $428,622 | Grant | Trans-NIH Recovery Act Research Support: When behavior thought to be characteristic of humans alone, is found in other animals using carefully controlled experiments, it may not be necessary to posit complex theories that are difficult to test. In the present proposal we will investigate in pige | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $390,244 | Grant | Trans-NIH Recovery Act Research Support: Alcohol abuse is one of the most common cause of liver fibrosis/cirrhosis in western developed countries. Alcoholic liver fibrosis is caused by the excessive accumulation of extracellular matrix (ECM) in the liver. Type I collagen is the major component o | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $52,735 | Grant | Trans-NIH Recovery Act Research Support: The dimorphic fungus Histoplasma capsulatum var. capsulatum [Hc] is the most prevalent cause of fungal respiratory infections. Hc infects approximately 500,000 individuals in the USA each year. Infection usually results in a mild, often asymptomatic res | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $394,646 | Grant | Trans-NIH Recovery Act Research Support: Coxiella burnetii is an obligate intracellular gram-negative bacterium that causes the worldwide zoonotic disease, Q fever. Natural human infections commonly occur via inhalation of infectious aerosols, manifest clinically as atypical pneumonia, and can d | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $380,842 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Asthma has been increasing in prevalence and severity for unknown reasons. Though our understanding of the pathophysiology remains poor, it is widely accepted that asthma is an inflammatory disease and CD4+ T cells ela | Health and Human Services, Department of / National Institutes of Health | 5/19/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $404,783 | Grant | Trans-NIH Recovery Act Research Support: Yersinia pestis translocate virulence factors from the bacterial cytoplasm into host immune cells during infections through the Type III Secretion System (TTSS). This system allows for rapid activation of injection of Yops, proteins that go on to disable | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| PURDUE UNIVERSITY | $3,946,282 | Grant | Trans-NIH Recovery Act Research Support: Program Director/Principal Investigator (Last, First, Middle): Kuhn, Richard J. 2 P01 AI055672-06A1 ABSTRACT The current understanding of alphavirus and flavivirus life cycles at the molecular level is incomplete because we lack a structural foundation fo | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| ALBANY MEDICAL COLLEGE | $4,640,929 | Grant | Trans-NIH Recovery Act Research Support: Overall Project : Francisella tularensis is considered to be a Category A agent by the NIAID because of its extreme infectivity, ease of dissemination, and substantial capacity to cause illness and death. This Program Project brings together a diverse gro | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $3,407,053 | Grant | Trans-NIH Recovery Act Research Support: The Biodemographic Determinants of Life Span-a collaborative effort between demographers/ biologists to bear on questions that are at the interzone between the biology of aging/formal demography, particularly questions concerned with the evolutionary, ge | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $2,395,610 | Grant | Trans-NIH Recovery Act Research Support: Project 1 aims to identify the brain networks influenced by acupuncture and to explore the interactions among those brain regions in both healthy subjects and in patients with major depressive disorder (MDD). We hypothesize that the limbic system and defa | Health and Human Services, Department of / National Institutes of Health | 5/11/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $7,417,151 | Grant | Trans-NIH Recovery Act Research Support: Pneumonic plague is highly lethal in humans, and the agent of this disease, Y. pestis, is considered a major threat as a biological weapon. Current strategies to prevent pneumonic plague, such as the use of vaccines or antibiotics, are non-effective or co | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $145,922 | Grant | Trans-NIH Recovery Act Research Support: Study of Osteoporotic Fractures Renewal. Data analysis and manuscript preparation. | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| WASHINGTON UNIVERSITY, THE | $860,962 | Grant | Trans-NIH Recovery Act Research Support: Leishmaniasis is a major health problem in humans and is caused by the protozoan parasite Leishmania. Depending on the species, Leishmania-induced pathology ranges from self-healing, cutaneous lesions to fatal, visceral diseases. Our laboratory has focuse | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| DUKE UNIVERSITY | $614,162 | Grant | Trans-NIH Recovery Act Research Support: The murine antibody repertoire experiences a series of expansions and contractions that coincide with specific stages of B-cell development and differentiation. The initial repertoire of antibody specificities generated by V(D)J recombination is reduced d | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $769,676 | Grant | Trans-NIH Recovery Act Research Support: Amalgamating the tools and techniques of molecular biology, genetics, biochemistry, and pharmacology, this competing renewal application offers an experimental paradigm to validate key components of the polyamine pathway of Leishmania and to implement a s | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $698,906 | Grant | Trans-NIH Recovery Act Research Support: Comstock, Laurie E. A10441 93-A2 The Bacteroides are one of the numerically dominant genera of bacteria of the human intestinal microbiota where they are mutualistic symbionts providing beneficial properties to the mammalian host. If Bacteroides fragilis | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF IOWA, THE | $750,000 | Grant | Trans-NIH Recovery Act Research Support: Klebsiella pneumoniae is an opportunistic pathogen frequently implicated in respiratory and urinary tract infections of hospitalized patients. In addition, it is a leading cause of pneumonia in chronic alcoholics and has also been associated with communit | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $787,500 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will not only help elucidate the pathogenic mechanisms of autoimmune encephalomyelitis but also aid in developing specific strategies targeting c Rel for the treatment of multiple sclerosis. | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $845,000 | Grant | Trans-NIH Recovery Act Research Support: A large number of medically important bacterial pathogens utilize a type III protein secretion system (T3SS) to deliver an arsenal of virulence-associated proteins into host cells to cause disease. The T3SS in these bacteria are centered on an intricate n | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $656,534 | Grant | Trans-NIH Recovery Act Research Support: Cryptosporidium parvum and C. homonis are opportunistic protozoan parasites frequently infecting AIDS patients and other immune-compromised individuals. The long-tem objective of this research is to use genetic methods to identify genes controlling specif | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $1,095,766 | Grant | Trans-NIH Recovery Act Research Support: This NIH NIAID RO1 competing continuation grant received ARRA support for years 6 and 7 to investigate how West Nile virus [WNV] persists and amplifies within the varied biomes of California. The project start date was 1 Jun 09. Funding transferred from | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| KANSAS STATE UNIVERSITY | $732,860 | Grant | Trans-NIH Recovery Act Research Support: Abstract: DESCRIPTION (provided by applicant): Hypoxia is a natural state in the lens. In order to prevent hypoxia-driven apoptosis the lens has two stress switch protein kinase C (PKC) isoforms, PKC3 and PKC5. Both of these PKC isoforms have C1B activati | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $1,150,829 | Grant | Trans-NIH Recovery Act Research Support: The major goal of this study is centered on biochemical characterization of molecular mechanisms that regulate thrombin generation and blood clotting pathways with specific aims focused on factor V, HDL and HDL lipids. Once clinical research aim addresse | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $790,203 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA award to support the research of R01 EY013135 entitled, 'Spatiotemporal Maps & Interactions in V1 & V2 Neurons.' The proposed experiments will use physiology to measure single-neuron responses to classical visual illusions, which have been | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $2,355,329 | Grant | Trans-NIH Recovery Act Research Support: Nonviral Gene Medicine for Hemophilia A -- The goal of this study is to develop a safe, efficient, and clinically feasible nonviral gene therapy strategy for the treatment of hemophilia A. Currently hemophilia A patients are treated with repeated infusio | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BAYLOR COLLEGE OF MEDICINE | $855,818 | Grant | Trans-NIH Recovery Act Research Support: 'This project is aimed at developing rational strategies for the prevention and treatment of lung diseases such as BPD and ARDS in humans.. Hyperoxia is frequently used in the treatment of pulmonary insufficiency in premature infants. However, hyperox | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $916,504 | Grant | Trans-NIH Recovery Act Research Support: Elevation of blood triglycerides, primarily as triglyceride-rich lipoproteins (TGRL), is a known risk factor for the development of atherosclerotic cardiovascular disease and increasingly linked to vascular inflammation. TGRL consist of chylomicrons, very | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $1,045,767 | Grant | Trans-NIH Recovery Act Research Support: Title: Dietary Patterns and Risk of Cardiovascular Disease Conventional classifications of saturated, monounsaturated, polyunsaturated, and trans fat incompletely capture the wide heterogeneity across >50 unique fatty acids. In this proposal, we put forth | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $840,000 | Grant | Trans-NIH Recovery Act Research Support: The longterm goal of our research program is to elucidate the complex neural processing of chemical and mechanical respiratory afferent inputs that underlie the control of breathing by brainstem nuclei in health and in cardiopulmonary diseases. In the pas | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NORTH DAKOTA | $695,038 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The dopamine transporter (DAT) is the primary mechanism by which extracellular dopamine (DA) is cleared from the synaptic space. As such it performs a key role in terminating dopaminergic neurotransmission and in regu | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $371,250 | Grant | Trans-NIH Recovery Act Research Support: The relevance of this research is for providing guiding information and principles concerning the understanding of both the normal processes and the drug-induced changes involved in the long-term consequences of drug exposure in the neural circuitry of th | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $879,973 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this project is to identify new, more effective, and less toxic therapies for Head and Neck Squamous Cell Carcinoma (HNSCC) and related cancers, by understanding the function and regulation of the p53 family members p63 and p73. | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $840,126 | Grant | Trans-NIH Recovery Act Research Support: Illuminating the arc of molecular events from chronic hepatic injury and fibrosis through hepatocellular carcinoma (HCC) remains the most fundamental challenge in investigative hepatology The overall goal of this application is to elucidate the role of t | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $732,083 | Grant | Trans-NIH Recovery Act Research Support: During aging, an increasing proportion of total lens proteins becomes water insoluble (WI) either due to aggregation and/or cross-linking. The increased sizes of cross-linked multimers of crystallins become so large that they finally become water insolubl | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $835,037 | Grant | Trans-NIH Recovery Act Research Support: Our long term objectives are to understand the biochemical mechanisms that cause the feedback inhibition of hormonal or drug stimulation of the 22-adrenergic receptor (22AR) that mediates several important components of the 'fight-or-flight' response thro | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WASHINGTON | $609,280 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic modifications modulate gene expression in normal development and in diseases, such as cancer. X chromosome regulation is an example of coordinate epigenetic regulation of gene expression at the level of an entire chromosome. Our goal is to inve | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $510,622 | Grant | Trans-NIH Recovery Act Research Support: Carbohydrates can be used as vaccines if they are covalently conjugated to a carrier protein. However, some carbohydrate antigens remain poor immunogens even when coupled to a protein. To overcome this weakness, chemical alteration of the native carbohydr | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| THE INSTITUTE FOR CANCER RESEARCH | $787,981 | Grant | Trans-NIH Recovery Act Research Support: Abstract: The objective of this proposal is to understand the mechanism for the 5G?? strand-specific end processing of DNA double-strand breaks (DSBs) in eukaryotes. DSBs are among the most deleterious types of DNA damages. If not properly repaired, DSBs | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $658,836 | Grant | Trans-NIH Recovery Act Research Support: The long-range goals of this project are to use polypyrrolebased anion receptors to understand the fundamental factors that regulate anion recognition and transport processes in biology and to develop synthetic systems that are useful in the diagnosis and | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF UTAH, THE | $806,933 | Grant | Trans-NIH Recovery Act Research Support: Dicer is a nuclease involved in processing double-stranded RNA (dsRNA) into small RNAs called siRNA and miRNA. These small RNAs are involved in regulating the expression of numerous genes, in diverse organisms, including humans. The proposal will focus on | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $647,749 | Grant | Trans-NIH Recovery Act Research Support: DExD/H-box proteins are required for virtually every process carried out by structured RNAs, from premRNA splicing and translation to intracellular trafficking of proteins and RNAs. These proteins are thought to use energy from ATP to facilitate RNA confo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON UNIVERSITY, THE | $613,407 | Grant | Trans-NIH Recovery Act Research Support: The encapsulated fungus Cryptococcus neoformans is responsible for life-threatening disease, particularly in the context of compromised immunity, and current therapy is not adequate. Extracellular glycans define the interface between this opportunistic pa | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $1,008,695 | Grant | Trans-NIH Recovery Act Research Support: Albino Deletion Complex and Early Mouse Development - ARRA Cellular differentiation from pluripotency is dependent on global shifts in genomic expression patterns and preservation of inherited transcriptional states throughout development of the mouse em | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| WASHINGTON UNIVERSITY, THE | $4,656,242 | Grant | Trans-NIH Recovery Act Research Support: The prevalence of childhood overweight (CO) has tripled in recent decades, and related health care costs have quadrupled. While lifestyle interventions for CO have produced promising short-term results, a substantial percentage of children regain all or m | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $1,416,180 | Grant | Trans-NIH Recovery Act Research Support: This renewal proposal explores mechanisms that regulate alternative pre-mRNA splicing in differentiating erythroid cells, focusing on cis-regulatory sequences and trans-acting splicing factor proteins that regulate erythroid stage-specific switches in exo | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $1,194,134 | Grant | Trans-NIH Recovery Act Research Support: Atrial fibrillation (AF) is a common arrhythmia and is assuming increased public health importance as the population ages. The overall objective of this project is to identify novel risk factors for the development of incident AF and to evaluate its natu | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| WAKE FOREST UNIVERSITY | $792,106 | Grant | Trans-NIH Recovery Act Research Support: High avidity CD8+ T cells are known to be the most effective mediators of viral clearance. Thus understanding how avidity is controlled following viral infection is of critical importance for designing optimally effective therapeutics and vaccines. Functi | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $1,399,605 | Grant | Trans-NIH Recovery Act Research Support: Light is the most potent stimulus to shift the phase of the endogenous circadian timing system. If properly timed, it is effective in the treatment of circadian phase misalignment as seen in circadian rhythm sleep disorders (e.g., delayed sleep phase synd | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BRANDEIS UNIVERSITY | $685,160 | Grant | Trans-NIH Recovery Act Research Support: Perception and memory are central to the ordinary but important activities of everyday life. When cooperative interactions between the two processes are undermined by genetic or acquired disorder, by drugs of abuse, by inattention, or by age-related chang | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $737,845 | Grant | Trans-NIH Recovery Act Research Support: Two years of support for this project will allow us to perform the experiments proposed in Aims 3 and 4 of the original application. We have been able to complete the bulk of Aims 1 and 2 with support from the American Heart Assoc. This supported our hypo | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| UNIVERSITY OF MARYLAND | $802,606 | Grant | Trans-NIH Recovery Act Research Support: The motor cortex of all mammalian species, including humans, contains a gross somatotopic representation of the major divisions of the body, such as hindlimb, forelimb, and face. Within each body part, there are multiple, non-contiguous, partially overlap | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $894,598 | Grant | Trans-NIH Recovery Act Research Support: Brain function depends critically on the normal operation of synapses and their capacity for modification. An understanding the basic properties of synaptic transmission and plasticity is necessary for illuminating the mechanisms of synaptic dysfunction i | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CINCINNATI | $8,081,413 | Grant | Trans-NIH Recovery Act Research Support: Our primary objective is to identify specific gene variants that are related to the formation and rupture of intracranial aneurysms (IA). Our experienced collaborative and highly productive team of Familial Intracranial Aneurysm (FIA) Investigators at 27 | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF MIAMI | $1,495,230 | Grant | Trans-NIH Recovery Act Research Support: Family Study of Stroke Risk and Carotid Atherosclerosis (2-R01-NS040807-07) Eleventh ARRA Quarterly Report: April 1st, 2012 G?? May 31st, 2012 The goal of the Family Study of Stroke Risk and Carotid Atherosclerosis is to identify genetic determinants of | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |