Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| DUKE UNIVERSITY | $998,996 | Grant | Trans-NIH Recovery Act Research Support: Three major trends in medicine offer a tremendous opportunity for Duke University and Durham County, NC to develop a model for population health that will provide insights applicable to the CTSA program and to create a novel, sustainable source of jobs fo | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $750,638 | Grant | Trans-NIH Recovery Act Research Support: Under the Biostatistics, Evaluation, Research, and Design (BERD) aims of he Rockefeller University CTSA parent grant 'to fine-tune u-scores to the specific challenges of clinical/translational research' and 'to facilitate use of the new statistical method | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $397,963 | Grant | Trans-NIH Recovery Act Research Support: This proposal addresses the following objectives: (1) Assure rapid and rigorous development, evaluation, and selection of pilot studies consistent with the mission of the CTSC; and (2) Maximize the scientific and training impact of pilot investigations. T | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $595,841 | Grant | Trans-NIH Recovery Act Research Support: The optimal treatment of chronic diseases represents a major challenge, including overcoming barriers such as access to health care. This proposal addresses the growing public health issue of diabetes and its complications. The incidence of diabetes is so | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF PITTSBURGH THE | $599,506 | Grant | Trans-NIH Recovery Act Research Support: Our goal is to improve our curriculum in clinical and translational science (CTS) by developing a competency-based educational structure across our CTS coursework. While our training is rigorous and our on-going evaluations of educational outcomes have | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF ROCHESTER | $1,212,610 | Grant | Trans-NIH Recovery Act Research Support: The project is to establish the Healthy Living Research Center at the University of Rochester. The Center will expedite research related to the translation of behavioral science to clinical and community programs and their comparative effectiveness. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| THE VANDERBILT UNIVERSITY | $551,188 | Grant | Trans-NIH Recovery Act Research Support: The Collaborative to Build Community Capacity for Research is a joint project of Vanderbilt University Medical Center, Meharry Medical College, and Tennessee State University which proposes to create sustainable mechanisms and processes to develop and enh | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF CHICAGO, THE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our community to determine the molecular underpinnings of disease or disease predisposition in | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $297,338 | Grant | Trans-NIH Recovery Act Research Support: Creating an Investigator Toolkit to Build a Dental CTSA Nexus The primary goal of this CTSA supplement is to create a web-based, clinical and translational dental research ?toolkit? that will expand the ability of the Dental CTSA programs to participate | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $299,937 | Grant | Trans-NIH Recovery Act Research Support: The goals of this administrative supplement are to use community health priorities to identify curricular needs, create novel teaching materials to address those needs, and effectively improve health science education in public schools. The health priorit | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF ROCHESTER | $764,231 | Grant | Trans-NIH Recovery Act Research Support: The long range goal of this translational-engineering research project is to improve the vision of people who have abnormal corneal conditions such as keratoconus. In the previous grant period, we developed the ability to measure wavefront error in these | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $824,532 | Grant | Trans-NIH Recovery Act Research Support: Through vision, we infer intrinsic properties of objects, including their shapes, sizes, materials, as well as their identities. We also infer their depths and movement relationships to each other and ourselves, as well as determine how to use this infor | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RED HILL STUDIOS | $909,505 | Grant | Trans-NIH Recovery Act Research Support: Red Hill Studios and the University of California, San Francisco (UCSF) School of Nursing propose to develop a computer game-based training program for patients with Parkinson's disease (PD). The program will feature a customizable Physical Gaming Regimen | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $341,095 | Grant | Trans-NIH Recovery Act Research Support: Poliovirus and related human enteroviruses cause a diverse spectrum of human diseases including acuteflaccid paralysis (paralytic poliomyelitis), aseptic meningitis, myocarditis, conjunctivitis and fatal systemicinfections of neonates. Poliovirus (PV), th | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $442,291 | Grant | Trans-NIH Recovery Act Research Support: Lack of a clear understanding of which CD8+ T cell responses and functions mediate control of HIV is substantially hampering development of an HIV vaccine. A major factor limiting CD8 T cell responses is the propensity of HIV to mutate and escape from the | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $322,892 | Grant | Trans-NIH Recovery Act Research Support: This projects seeks to understand the membrane biology of Treponema pallidum through elucidation of the organisms membrane liproproteins. Such structure and function information could be central to the rational design of a future syphillis vaccine. | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $687,550 | Grant | Trans-NIH Recovery Act Research Support: Antisense oligonucleotides (AONs) are important tools for the specific modulation of gene expression. They are applied widely in the research laboratory for gene 'knockdown' studies, and they are being developed clinically as therapeutics for a wide range | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| WAKE FOREST UNIVERSITY | $1,783,650 | Grant | Trans-NIH Recovery Act Research Support: Adequate housing is a fundamental human right. However, the limited research that has been conducted demonstrates that inadequate housing is the most basic of all of the unjust and inequitable conditions that farmworkers in North Carolina and the southeas | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $805,866 | Grant | Trans-NIH Recovery Act Research Support: A rate limiting step in the development of therapeutic agents for treating diabetic retinopathy is retinal drug delivery. Although intravitreal injections allow significant drug delivery to the retina, repeated intravitreal injections can lead to endophth | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $667,544 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to gain a better understanding of the mechanism governing fidelity during protein synthesis and specifically to extend the description of the ribosomal structures responsible for maintaining accuracy. | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| CORNELL UNIVERSITY, INC | $372,293 | Grant | Trans-NIH Recovery Act Research Support: Microtubules play essential roles in a variety of cellular processes, including chromosome segregation and organelle transport. They are dynamic polymers that alternate frequently between phases of growing and shrinking, a property that allows the rapid r | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $635,096 | Grant | Trans-NIH Recovery Act Research Support: Although vision, olfaction and taste are understood, at the level of molecules, we do not understand mechanical senses such as touch, hearing, blood pressure, osmotic balance. Even when ion channels of the TRP superfamily are suspected to transduce mecha | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $555,154 | Grant | Trans-NIH Recovery Act Research Support: Continual dynamic remodeling of the actin cytoskeleton, in response to intrinsic and extrinsic signals, is critical for the execution of many eukaryotic cell functions including cell cycle progression, cell motility, secretion and recovery from cellular/e | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ALBANY MEDICAL COLLEGE | $587,733 | Grant | Trans-NIH Recovery Act Research Support: In normal wound repair connective tissue cells called 'fibroblasts' become activated for several days until the wound has healed and a small scar is deposited. The fibroblasts then go away. However, in diseases in which scarring is excessive, these acti | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NEBRASKA | $627,878 | Grant | Trans-NIH Recovery Act Research Support: Lipid homeostasis is maintained through a complex network of hormonal, neuronal and environmental regulators. Inability to modulate lipid metabolism to maintain homeostasis is a hallmark of many disease states including metabolic syndrome, obesity, diabet | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $484,008 | Grant | Trans-NIH Recovery Act Research Support: Many human diseases arise from errors in the molecular machinery for communication/signaling between and within cells, and a detailed understanding of the molecular events responsible will allow the design and development of therapeutic agents that can co | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF MARYLAND | $570,000 | Grant | Trans-NIH Recovery Act Research Support: Spermatogenesis is regulated by a cascade of regulatory events involving activation of a robust transcription program in spermatocytes. Understanding the mechanisms that control this program is critical for identification of generic defects that disrupt s | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $586,005 | Grant | Trans-NIH Recovery Act Research Support: This research seeks to exploit diastereoselective routes to bicyclic-¿-lactones to access antitumor, antibacterial and anti-inflammatory agents of interest for human health and as tools for studying basic biological processes. In this grant period, w | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WASHINGTON | $603,052 | Grant | Trans-NIH Recovery Act Research Support: RNA-binding proteins perform essential functions in every aspect of RNA biogenesis. These functions are a fundamental aspect of basic cellular physiology, and numerous human diseases arise from defects in the function of these proteins. The biological act | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| DREXEL UNIVERSITY | $1,018,829 | Grant | Trans-NIH Recovery Act Research Support: The objective of our research is to develop therapeutic approaches for hypoxic brain damage in the newborn by elucidating cellular and molecular mechanisms of cerebral injury induced by hypoxia and by assessing the efficacy of selective inhibitors for pre | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,039,836 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to continue a unique microlevel study of the reciprocal relationships between population processes (marriage, fertility, and migration) and the environment (land usefcover, vegetation abundance and species diversity, and consumption of | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $1,484,709 | Grant | Trans-NIH Recovery Act Research Support: The award focuses on 2 schemas to classify LBP: 1) the Treatment-Based Classification (TBC) system, from which clinical prediction rules about who is most likely to benefit from spinal stabilization exercises have been developed, and 2) the Movement Syste | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF WASHINGTON | $767,447 | Grant | Trans-NIH Recovery Act Research Support: A reoccurring observation in the study of genes involved in reproduction is their rapid, adaptive divergence. We have demonstrated the rapid divergence of ten genes involved in reproduction by analyses of rates and patterns of divergence between primates. | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| WASHINGTON UNIVERSITY, THE | $2,267,000 | Grant | Trans-NIH Recovery Act Research Support: This project aims to define the roles of inositol signaling reactions in the pathogenesis of disease. We will study the role of inositol 1,3,4-5/6-kinase in fat cell differentiation. This enzyme catalyzes the first step in formation of inositol hexakispho | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $1,437,673 | Grant | Trans-NIH Recovery Act Research Support: We are investigating the regulation of the enzymatic formation 01 reactive oxygen species (ROS) by NAOPH oxidases (Nox). The current goals address two areas; 1) How Rae GTPase binds to and regulates Nox activity; and 2) The regulation of Nox activity by S | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $1,366,682 | Grant | Trans-NIH Recovery Act Research Support: Neural regulation of immature airways serves to balance airway smooth muscle [ASM] contractile and relaxant pathways. This balance is readily disrupted in early postnatal life and may predispose to later airway hyperreactivity. In the two previous cycles | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WASHINGTON UNIVERSITY, THE | $1,117,955 | Grant | Trans-NIH Recovery Act Research Support: Lung transplant (LTx) is a viable treatment option for a variety of end-stage pulmonary parenchymal and vascular diseases. Advancements in surgery, immunosuppression and recipient selection have significantly improved perioperative survival following LTx. | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| THE VANDERBILT UNIVERSITY | $1,106,413 | Grant | Trans-NIH Recovery Act Research Support: Heart disease continues to be the leading cause of death in the United States and is associated with a variety of clinical abnormalities, including congestive heart failure, ventricular remodeling, ischemia, ion homeostasis, arrhythmias, and sudden cardia | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $980,780 | Grant | Trans-NIH Recovery Act Research Support: Xenotransplantation (Xtr) is of interest because of the insufficient supply of human organs. The pig is considered a likely donor species for humans, but there are major barriers to successful Xtr. The first two barriers, hyperacute rejection (HAR) and ac | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $805,604 | Grant | Trans-NIH Recovery Act Research Support: This award funds the project titled: ?Chronic hypoxia and pulmonary vascular smooth muscle?. The funded activity includes conducting experiments aimed at characterizing the effects of prolonged exposure to hypoxia on pulmonary arterial smooth muscle cells | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $908,401 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of this research project are to provide information on the molecular basis for the heterogeneity of voltage-gated potassium (Kv) channels in normal and in diseased hearts, and the mechanisms/sites of actions of currently available | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| WASHINGTON UNIVERSITY, THE | $1,848,972 | Grant | Trans-NIH Recovery Act Research Support: Hypertension (HTN), a disease that affects over 65 million Americans, is one of the most common chronic diseases in the world. Hypertensive heart disease (HHD) phenotypes, including left ventricular (LV) hypertrophy (LVH), LV diastolic dysfunction (LVDD), | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| BAYLOR COLLEGE OF MEDICINE | $846,385 | Grant | Trans-NIH Recovery Act Research Support: Tobacco related lung diseases, including chronic obstructive pulmonary disease (COPD) with and without emphysema, are among the major causes of lung-related disability and death worldwide. The immediate cause of emphysema is destruction of lung matrix, es | Health and Human Services, Department of / National Institutes of Health | 5/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $1,396,043 | Grant | Trans-NIH Recovery Act Research Support: Peripheral arterial disease (PAD) is characterized by lower limb arterial obstruction due to atherosclerosis that impairs blood flow to the lower limb. PAD is quite common with over 8 million affected individuals in the U.S. Over the past 6 years, our mul | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $1,881,285 | Grant | Trans-NIH Recovery Act Research Support: Genome-wide association studies (GWAS) provide a new and powerful approach to investigate the effect of inherited genetic variation on risks of complex diseases. With recent advances in genotyping technology, genome-wide association studies are now becomi | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $853,071 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Selective Attention and Control Mechanisms in the Brain. Mechanisms of attention are critical for efficiently processing relevant information and avoiding distraction amidst a constant flood of sensory input. If these mechanisms are damaged, cognit | Health and Human Services, Department of / National Institutes of Health | 5/05/2009 |
| NEW YORK UNIVERSITY (INC) | $914,182 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Neurotrophins, such as NGF and BDNF, are prominent regulators of neuronal survival, growth and differentiation during development of the vertebrate nervous system. The actions of neurotrophins are dictated by two class | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $351,903 | Grant | Trans-NIH Recovery Act Research Support: This application seeks a third Competitive Renewal of application T32 AR007605 'Genetic Mechanisms in Skin Diseases' for continued funding of an established training program in Investigative Dermatology at Columbia University, College of Physicians & Surg | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| UNIVERSITY OF MIAMI | $907,120 | Grant | Trans-NIH Recovery Act Research Support: This study can provide usefull knowledge about organizational processes, including processes leading to organizational change, that are involved in the succsful integration of high-quality drug abuse treatment services in the juvenile justice settings and | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $99,140 | Grant | Trans-NIH Recovery Act Research Support: The supplementary funding allowed us to hire two part time research assistants to work on the data that has already collected to enhance our current parent study. The central goal of this supplement is twofold: (1)maximize our targeted subject sample and | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| HOWARD UNIVERSITY, INC. | $58,842 | Grant | Trans-NIH Recovery Act Research Support: The DC- Baltimore Research Center on Child Health Disparities has expanded its research goals to include research on the science of eliminating health disparities with a focuson gene-environment interactions related to child disparities. | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $98,084 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The purpose of the Center for Enhancement of Self-management in Individuals and Families (The Center) at the University of Wisconsin-Milwaukee College of Nursing (CON) is to expand programs of research aimed at enhanci | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $443,199 | Grant | Trans-NIH Recovery Act Research Support: This supplemental proposal is designed to enhance and fully develop the capabilities of the WVU Genomics Core Facility to support translational research studies by both clinical and basic science investigators at West Virginia University. The proposal bu | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $54,000 | Grant | Trans-NIH Recovery Act Research Support: FAK IN STRESS-ACTIVATED SIGNALING AND TUMOR INVASION This new work to be supported by the ARRA supplement to grant 5K08CA104039-5 is sharply focused on human colorectal carcinogenesis specifically and particularly on very early stages of this process, i | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| YALE UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: I am a National Library of Medicine research postdoctoral fellow in the Department of Molecular Biophysics and Biochemistry at Yale University. With this training/research proposal, I am applying to the Career Development Award. I had degreed education in | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $500,660 | Grant | Trans-NIH Recovery Act Research Support: The Arkansas IDeA Network of Biomedical Research Excellence (INBRE) has as its primary goal the expansion of biomedical research capacity in Arkansas in the fields of Cellular Signaling, Growth and Differentiation. A critical component of the Arkansas INB | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF NEBRASKA | $400,000 | Grant | Trans-NIH Recovery Act Research Support: This COBRE application proposes to continue The Nebraska Center for Cellular Signaling that was established to strengthen the research within UNMC and particularly the College of Dentistry. The stated objectives of the Center were 1) to expand the current | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF LOUISVILLE | $599,437 | Grant | Trans-NIH Recovery Act Research Support: Quarterly Activities/Project Description - We will demonstrate mechanisms by which PCBs and OCPs act synergistically with hyperlipidemia in cell culture resulting in (i) decreased adiponectin production from adipocytes, and (ii) increased foam cell format | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THOMAS JEFFERSON UNIVERSITY | $50,002 | Grant | Trans-NIH Recovery Act Research Support: The Kimmel Cancer Center at Jefferson has been selected as an Early Adopter Center of NCIG??s Clinical Trials Reporting Program (CTRP). As such, KCC is required to use the new system beginning with trials initiated in September 2009, and report to NCI on | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| YALE UNIVERSITY | $99,800 | Grant | Trans-NIH Recovery Act Research Support: The Yale PKD Center has established one of the most complete arrays of in vivo models of polycystic kidney disease available. Most of these in vivo models produce cysts by somatic second hit mutations. One of the challenges facing all Center investigator | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $373,168 | Grant | Trans-NIH Recovery Act Research Support: Determinants of Social, Communicative, and Other Core Deficits in Autism. This is a request for an administrative supplement for our Autism Center of excellence, P50HD055784, entitled Determinants of Social, Communicative, and Other Core Deficits in Autis | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF MASSACHUSETTS | $86,000 | Grant | Trans-NIH Recovery Act Research Support: My lab studies the circuitry of cellular signaling pathways and one of our long-term goal is to define which connections are critical in vivo to the progression of human cancer and to use that knowledge to facilitate the development of targeted therapies. | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| YALE UNIVERSITY | $288,433 | Grant | Trans-NIH Recovery Act Research Support: The research program features state-of-the-art computational design, organic synthesis, biological assaying, and crystallography aimed at delivering clinical candidates with striking potential for combating HIV/AIDS. The aims are to (1) develop improved t | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The interleukin 4 receptor alpha chain (IL-4Ra) plays a key role in the evolution of allergic inflammatory responses. However, whereas the function of its dedicated transcription factor Stat6 in promoting allergic inflammation is well established, those o | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NEBRASKA | $197,273 | Grant | Trans-NIH Recovery Act Research Support: Invasive breast cancer in women is a leading cause of cancer deaths in the US each year. Approximately 25% of these malignancies overexpress the tyrosine kinase receptor ErbB2/neu, which serves as a prognostic marker and therapeutic target. The oncoprote | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $756,831 | Grant | Trans-NIH Recovery Act Research Support: Multiple myeloma (MM) is the second most common hematopoietic cancer. MM ultimately becomes refractory to treatment when self-renewing MM cells begin unrestrained proliferation by unknown mechanisms. Our goal is to develop novel and superior therapeutic s | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $158,561 | Grant | Trans-NIH Recovery Act Research Support: This ARRA-funded award is a research supplement to support two students: pre-doctoral trainee Ms. Nafissatou Cisse and post-doctoral student Ms. Claudia Carrizosa. They will be mentored by leaders within the research community -- including the principal | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $289,999 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent grant is to test treatments to improve executive function among stimulant addicts. The purpose of this supplement is to fund hiring of an additional FTE employee in order to extend this approach to individuals who have alcohol depen | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $58,529 | Grant | Trans-NIH Recovery Act Research Support: The parent grant RO1 DC DC007678 ?Molecular mechanisms of vestibular hair cell exocytosis? aims at elucidating the molecular mechanisms underlying exocytosis in type I and type II hair vestibular hair cells in the utricle. The major goal of this administr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| YALE UNIVERSITY | $99,998 | Grant | Trans-NIH Recovery Act Research Support: Cytosolic Ca2+ is a critical second messenger in virtually every type of cell. Ca2+ is novel relative to other messenger molecules because it regulates multiple processes simultaneously within an individual cell. The ongoing theme of this research project | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $429,000 | Grant | Trans-NIH Recovery Act Research Support: Mycobacterium tuberculosis survives and persists for prolonged periods within its host in an asymptomatic, latent state and can reactivate years later when the host's immune system weakens. Accumulating evidence suggests that persistent bacilli are in a | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $460,500 | Grant | Trans-NIH Recovery Act Research Support: CMV infection in solid organ transplant (SOT) recipients strongly impacts the course of recovery and success rate of this therapy. Increased morbidity that reflects the severity of infection, which can lead to graft loss and patient death, is associated w | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $185,039 | Grant | Trans-NIH Recovery Act Research Support: TITLE: Genetics of Programmed Cell Death in Arabidopsis DESCRIPTION: The parent award for this Supplemental request asks two broadly relevant questions with respect to the control of programmed cell death in eukaryotes: 1. Since appropriate localization | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $50,240 | Grant | Trans-NIH Recovery Act Research Support: Understanding what modulates cadherin-mediated adhesion at adherens junctions (AJs) has widespread implications for understanding and treating defects during embryonic development, and for diagnosing and treating metastatic tumors. One key unresolved issu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $160,537 | Grant | Trans-NIH Recovery Act Research Support: The work to be completed using these supplemental funds will extend the aims of the parent grant, which aims to understand how the Distalless (Dll) gene is regulated during appendage development. The approach to be supported here will be to use the cgChIP | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $489,167 | Grant | Trans-NIH Recovery Act Research Support: We are submitting a revision to the parent R01 application (GM058615) in response to an NIH announcement (NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications). The parent grant studies transport vesicl | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CINCINNATI | $102,341 | Grant | Trans-NIH Recovery Act Research Support: Posttranscriptional modifications in ribosomal ribonucleic acids (rRNAs) are difficult to identify and their function is unknown. Our knowledge of the functional role of these posttranscriptional modifications is limited largely by the lack of methods for | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HEALTH RESEARCH, INC. | $117,259 | Grant | Trans-NIH Recovery Act Research Support: The broad objectives of the research proposed here are to elucidate the functions of the centrosome in vertebrate somatic cells, and the molecular mechanisms by which it accomplishes these functions. To achieve these goals we are using a unique approach i | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $410,382 | Grant | Trans-NIH Recovery Act Research Support: The proposed research will investigate the spectrum of changes in gene expression during genotoxic stress. Particular focus will be on genes normally expressed in preparation for DNA replication and repair of DNA damage. This wilt be correlated with the c | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF LOUISVILLE | $135,714 | Grant | Trans-NIH Recovery Act Research Support: Laboratory supplies used by a graduate student is supported by this administrative supplement. Because of a mismatch between the grant term and the academic semester, the student previously supported was moved to a teaching assistant ship, and a request t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $233,737 | Grant | Trans-NIH Recovery Act Research Support: AKAPs had originally been thought of as anchoring the cAMP-dependent protein kinase A (PKA), to downstream targets of cAMP/PKA actions. However, in recent studies we have found that several isoforms of the enzyme that produces cAMP, adenylyl cyclase (AC) | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| BRANDEIS UNIVERSITY | $9,311 | Grant | Trans-NIH Recovery Act Research Support: Bone morphogenetic proteins (BMPs) have been implicated as control factors in many different developmental transitions. During nervous system development BMPs regulate neural induction, formation of the neural crest, and the development of both neurons a | Health and Human Services, Department of / National Institutes of Health | 7/09/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $76,512 | Grant | Trans-NIH Recovery Act Research Support: These studies address the fundamental mechanisms by which SUMO modification regulates gene expression in human cells. Altered SUMOylation is associated with cancer, neurodegeneration and other diseases in humans. Increased understanding of SUMO function | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $25,543 | Grant | Trans-NIH Recovery Act Research Support: Polyploidy resulting from the fertilization of an egg by more than one sperm will be fatal to an embryo. Fertilization of an egg by two sperm will results in a triploid embryo. Triploidy is detected in ~10% of spontaneous abortions and the majority of tri | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $264,944 | Grant | Trans-NIH Recovery Act Research Support: Human reproduction is inefficient with only one-fourth to one-third of fertilized human eggs likely to survive to produce a term delivery. The causes of early reproductive failures are substantially unknown, but a growing body of evidence suggests that th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CONNECTICUT | $78,804 | Grant | Trans-NIH Recovery Act Research Support: Neurological impairment due to oxygen deprivation (hypoxia/ischemia or HI) is a common mechanism of damage to the premature and/or very low birth-weight (VLBW) infant brain. Such injuries contribute to a significant increase in the incidence of long-term | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $155,377 | Grant | Trans-NIH Recovery Act Research Support: Chronic pain is an important public health issue, affecting as many as 15-30% of adolescents. Over half of these adolescents report sleep disturbances, such as insomnia, that have the potential to diminish normal daily function, disturb mood, and reduce q | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ROCHESTER | $9,657 | Grant | Trans-NIH Recovery Act Research Support: The supplement will provide detailed pharmaceutical data to determine if women who receive an epidural during delivery are at higher risk for premature breastfeeding termination or early supplementation with formula. The parent grant will use these findin | Health and Human Services, Department of / National Institutes of Health | 6/24/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $47,848 | Grant | Trans-NIH Recovery Act Research Support: The equipment purchased with this grant will be devoted to the aims of the grant to which this supplement applies. Specifically, in grant 5R01HD056370-02, we propose to study the electrophysiological and circuit alterations in a mouse model of Fragile X | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $141,834 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award is in response to Notice Number NOT-OD-056 announcing the Availability of Recovery Act funds for Administrative Supplements to active grants. The overarching project investigates factors contributing to iron deficiency anemia in in | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $123,200 | Grant | Trans-NIH Recovery Act Research Support: Osteoporosis is a complex disease causing considerable morbidity and mortality from fracture. Bone mineral density (BMD) and bone geometry (BG) vary with sex and race and are both highly heritable. BMD and BG are the main determinants of bone strength, wh | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $945,582 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is associated with the parent grant G?Collectins and Innate Defense against Inhaled Pathogens, Grant # 1-PO1-AI083222-01A2 (B. Seaton, PI). We will use this supplementary funding to extend the parent grantG??s studies on co | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $117,961 | Grant | Trans-NIH Recovery Act Research Support: Atherosclerosis is a chronic inflammatory disease, characterized by neointimal plaque formation due to endothelial dysfunction, the infiltration by T lymphocytes (T cells) and macrophages, and proliferation and migration of vascular smooth muscle cells (V | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THOMAS JEFFERSON UNIVERSITY | $238,964 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that mice lacking arrestin-2 will have defects in thrombus formation in vivo, particularly in models that are selectively thrombin-dependent. Supplementary Aim I is to characterize thrombus formation in arrestin2-/- mice in thrombin-depend | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $289,520 | Grant | Trans-NIH Recovery Act Research Support: Project Title: New Avenues in GPIHBP1 Research 1a. Award Description Testing the hypothesis that GPIHBP1 plays an active role in the entry of Lipoprotein Lipase (LPL) into capillaries. 1b. Quarterly activity/Project Description Specific aim 1: To use | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| YALE UNIVERSITY | $100,124 | Grant | Trans-NIH Recovery Act Research Support: Neurons are the most polarized cells known. Regulated assembly and disassembly of actin filament and microtubule cytoskeletal proteins is fundamental to generation of neuronal polarity and regulation of neuronal growth. Recent developments in imaging tech | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| IRIS AO, INC. | $99,999 | Grant | Trans-NIH Recovery Act Research Support: Funds from this administrative supplement will be used to purchase a white-light interferometer in order to calibrate high-stroke deformable mirrors. At this stage, we have conducted in-depth evaluations of two different instruments from US-based vendors: | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| TRUDEAU INSTITUTE INC | $9,790 | Grant | Trans-NIH Recovery Act Research Support: The undergraduate summer student will assist in the experiments to define the parameters of the generation of CD8 memory T cells of the Tc17 subset, define how well they protect against lethal influenza A challenge when transferred to na+?ve recipients an | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $183,305 | Grant | Trans-NIH Recovery Act Research Support: The development of non-toxic medical countermeasures against gastrointestinal radiation injury is an unmet need. These countermeasures would benefit the population exposed to a radiation disaster or nuclear attack, as well as first-responders who enter a | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| EMORY UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Pro-Apoptotic Therapeutics with Kinase Inhibition in Neuroblastoma Neuroblastoma (NB) is a highly lethal solid tumor of childhood. Most patients eventually die of their disease due in part to the tumor's inability to die by programmed cell death leading t | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Nephronophthisis (NPHP) is an important public health issue because it is the most common genetic cause of end-stage renal disease in the first three decades of life. The kidneys of patients with NPHP demonstrate scarring and cyst formation, features shar | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $112,730 | Grant | Trans-NIH Recovery Act Research Support: This proposal is a for a ARRA administrative supplement, that entails the non viral mediated gene delivery to the retina for retinal degenerative diseases. It focuses on two types of retinal degenerations, RPE65 Leber s Congenital amauriosis, a retinal pi | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $81,510 | Grant | Trans-NIH Recovery Act Research Support: General anesthesia is one of the great advances of medicine but is not without risks. Subtle central nervous toxicity may be one of them. In neonatal animals, several general anesthetic agents have been implicated in neurodegeneration, hippocampal dysfunc | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| YALE UNIVERSITY | $35,766 | Grant | Trans-NIH Recovery Act Research Support: This application requests supplemental funds to enhance progress on the parent grant and to encourage students to pursue careers in health-related sciences. We have found that chronic stimulation through NOD2 in primary peripheral monocyte-derived human | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE INSTITUTE FOR CANCER RESEARCH | $147,525 | Grant | Trans-NIH Recovery Act Research Support: Title G?? The porphobilinogen synthase family. Abstract G?? Porphobilinogen synthase (PBGS) catalyzes the first common step in the biosynthesis of the tetrapyrrole pigments such as heme and is a primary target for the environmental toxin lead (Pb2+). Aim | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $291,223 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA award to R01 EY011379 'Functional Organization of Visual Area MT to enable the hiring of a new research technician and to purchase a 32-channel recording system for chronic multi-electrode recording | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $355,921 | Grant | Trans-NIH Recovery Act Research Support: Our research goals in the parent grant were to identify novel genes, mutations, and pathways associated with the molecular etiology of cataracts. We have genetically evaluated three novel mouse cataract loci: lop11, lop13 and bs2. These three models are | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| YALE UNIVERSITY | $299,240 | Grant | Trans-NIH Recovery Act Research Support: The brain organizes information about the sensory world into maps. Prominent examples are the maps of eye-preference and retinotopy in the lateral geniculate nucleus, superior colliculus and visual cortex. Experiments in this proposal will advance our und | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| YALE UNIVERSITY | $186,778 | Grant | Trans-NIH Recovery Act Research Support: We study the structure and function of group II introns, which are large ribozymes that function as selfsplicing RNAs and mobile genetic elements. Group II introns are important model systems for understanding RNA tertiary structure, RNA folding, and for | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $153,791 | Grant | Trans-NIH Recovery Act Research Support: The ribosome is the catalyst of protein synthesis in all living organisms. The peptidyl transferase center (PTC) is an evolutionarily ancient active site, extensively conserved through all biological kingdoms, with regard to both its sequence and its sub | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NORTH CAROLINA STATE UNIVERSITY | $320,787 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an administrative supplement to enable incorporating a proteomics component in specific aim 2 of grant R01-GM059469 (Molecular genetics of olfaction in Drosophila). This specific aim focuses on assessment of naturally occurring varia | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $560,686 | Grant | Trans-NIH Recovery Act Research Support: The grant supports the Drosophila RNAi Screening Center, a 'technology transfer' center that hosts researchers for Drosophila RNAi screening, an approach useful to study a wide array of cellular events, behaviors and pathways with relevance to human disea | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | $140,910 | Grant | Trans-NIH Recovery Act Research Support: Recently it has it become clear that human mitochondria contain their own unique pathway for synthesizing fatty acids. Initial studies have implicated the pathway in the supply of octanoyl precursors required in the lipoylation of essential mitochondrial | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | $214,856 | Grant | Trans-NIH Recovery Act Research Support: Our parent grant proposal has two aims: (1) To identify the regions in the actomyosin complex involved in transforming the biochemical energy into directed mechanical movement and (2) to determine the structural correlates that contribute to the biochemic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $7,885 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award is a supplement to the parent grant: Children with MR: Family Processes and Dual Diagnosis, funded by NICHD. A sample of 200 families, with or without a child with intellectual disability (ID), has been followed from child age 3 through | Health and Human Services, Department of / National Institutes of Health | 6/23/2009 |
| UTAH STATE UNIVERSITY | $132,173 | Grant | Trans-NIH Recovery Act Research Support: ARRA ? Trophoblast MHC-I: Trigger for Immune-Mediated Rejection of Cloned Bovine Fetuses. Immune-mediated rejection is an important, although poorly understood and often unrecognized, cause of pregnancy failure in women. Both spontaneous rejection and pre | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| YALE UNIVERSITY | $330,265 | Grant | Trans-NIH Recovery Act Research Support: The mechanisms of successful long-term vein graft adaptation to the arterial environment without excessive intimal thickening are still not completely understood. Several members of the Ephrin-Eph pathway have recently been described as developmentally sp | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $154,000 | Grant | Trans-NIH Recovery Act Research Support: Title of parent grant: G?Sex chromosome effects on neural developmentG? The overall goal of the parent project is to determine the effects of sex chromosome complement on sex differences (1) in stress effects on the gastrointestinal system and (2) on noc | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $31,576 | Grant | Trans-NIH Recovery Act Research Support: Studies of Neurogenesis and Progenitor Responses During Neural Repair after Stroke. Stroke is the leading cause of adult disability. One potential mechanism of neural repair is post-stroke neurogenesis. In this process, newly born cells migrate from their | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| UNIVERSITY OF KANSAS CENTER FOR RESEARCH, INC. | $523,386 | Grant | Trans-NIH Recovery Act Research Support: Complex diseases are controlled by a large number of potentially interacting genetic and environmental factors. Each year millions of Americans are diagnosed with complex diseases such as diabetes, heart disease, Alzheimer's, and various forms of cancer. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF WYOMING | $42,900 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the parent grant (R01NS057415) is to understand the mechanisms by which the developing inhibitory networks are able to adapt to sensory inputs and to maintain their balance with the developing excitatory networks. The proposed supple | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF TENNESSEE | $36,600 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent application is to investigate the ability of olfactory input to increase the strength of olfactory nerve (ON) synapses in an activity-dependent fashion. Specifically, we intended to answer the question of whether a brief the | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WYOMING | $45,591 | Grant | Trans-NIH Recovery Act Research Support: The funding supports half of the cost for purchasing an inverted fluorescence microscope (Leica DMI6000 with time-lapse and cell incubation unit), which will be extensively used in our studies, including localization of cell signaling mediators, in vitro | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $338,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this Administrative Supplement to R21 AI078466 is to design and produce HIV-1 immunogens for generating an HIV-1 neutralizing antibody response directed against the membrane-proximal ectodomain region (MPER) of the gp41 transmembrane envelope | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF LOUISVILLE | $16,631 | Grant | Trans-NIH Recovery Act Research Support: Research Training supplement - opportunity for 2 students to learn research design and methods and data analysis for the summer research supplement: General Research plan: The summer high school and undergraduate student worked with the principal researc | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF TENNESSEE | $34,273 | Grant | Trans-NIH Recovery Act Research Support: The neurohypophysial hormones vasopressin (VP) and oxytocin (OT) are synthesized in the magnocellular neurons (MNCs) located within the paraventricular (PVN) and the supraoptic (SON) nuclei of the hypothalamus, and released from the neurohypophysis into t | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| SAN DIEGO STATE UNIVERSTIY FOUNDATION | $166,962 | Grant | Trans-NIH Recovery Act Research Support: The goal of the SDSU Bridges program is to train 18 students a year from the three partnering colleges to complete their bachelors degree training, despite high GPA requirements for transfer and entry into the impacted biology major at SDSU. The outcome o | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| YALE UNIVERSITY | $115,937 | Grant | Trans-NIH Recovery Act Research Support: The recent resurgence of important infectious diseases has led to a need for K-12 school curricula that create a better understanding of disease transmission dynamics and their biological underpinnings. To produce these curricula, Lyme disease and West Ni | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF ARKANSAS SYSTEM | $99,836 | Grant | Trans-NIH Recovery Act Research Support: Aspects of Biotin Nutrition-supplement: The long-term goals of this research project are 1) Determine the biotin requirement of normal individuals and of individuals in specific clinical circumstances in which biotin status may be impaired and 2) Investi | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| YALE UNIVERSITY | $43,892 | Grant | Trans-NIH Recovery Act Research Support: This Training Program was completely restructured in 2002 in response to the evolution of physiology in the post-genomic era. With the sequencing of the genomes of various organisms including the human, significant strides have been made towards understan | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| CHILDREN'S HOSPITAL & RESEARCH CENTER | $1,422,674 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to support the following aims: (1) accelerate the human leucocyte antigen (HLA) genotyping efforts in our case/control study of the role of HLA and killer-cell immunoglobulin-like receptor (KIR) polymorphism in Crohn's Disease (CD) | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $1,970,379 | Grant | Trans-NIH Recovery Act Research Support: UCLA AIDS PREVENTION AND TREATMENT CLINICAL TRIALS UNIT The UCLA AIDS Prevention and Treatment Clinical Trials Unit (UCLA-APT-CTU) is a multidisciplinary research unit composed of a core administrative unit and four clinical research sites in metropolitan | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| YALE UNIVERSITY | $82,750 | Grant | Trans-NIH Recovery Act Research Support: This Research Plan is submitted in response to the Notice of Availability of Recovery Act Funds for Administrative Supplements (NOT-OD-09-056), for the purpose of enhancing our role as a Genetic Research Center (GRC), in the larger NIDDK IBD Genetics Cons | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| YALE UNIVERSITY | $748,112 | Grant | Trans-NIH Recovery Act Research Support: The processes that cause destruction of beta cells that leads to Type 1 and Type 2 diabetes are silent. Their effects can only be appreciated after there has been considerable destruction of cells and the level of glucose rises. However for years before e | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $291,380 | Grant | Trans-NIH Recovery Act Research Support: The parent grant for this supplemental proposal aims to understand the neural organization of auditory language perception/comprehension at the phonological, lexical,and sentence levels. It has two arms, functional imaging (fMRI) in healthy adults and beh | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $163,595 | Grant | Trans-NIH Recovery Act Research Support: Death of auditory hair cells is the primary cause of hearing loss and tinnitus. All mammals, including humans, are unable to form new auditory hair cells, and as a result, hearing loss and tinnitus are permanent conditions. In contrast, many mature anim | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $119,203 | Grant | Trans-NIH Recovery Act Research Support: The focus during the first 10 years of funding for grant R01-DC003732 has been to define the role of the vestibular system in adjusting respiratory muscle activity during movement and changes in posture. The final year of the currently-funded grant propos | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF WASHINGTON | $158,851 | Grant | Trans-NIH Recovery Act Research Support: It is estimated that 10% of the population is affected by sensorineural or nerve deafness that usually arises from sensory hair cell loss or damage. Sensory deficits resulting from hair cell loss have been considered irreversible because the production o | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| HOUSE EAR INSTITUTE INC | $285,086 | Grant | Trans-NIH Recovery Act Research Support: The plan of this supplement is to apply new technology in the form of high-throughput Next Generation sequencing to analyze the entire transcriptome of the embryonic cochlea duct across the temporal and spatial gradient of p27 expression. To do this we wi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $163,548 | Grant | Trans-NIH Recovery Act Research Support: Synaptic mechanisms of inhibition represent some of the greatest gaps in our understanding of the processing of acoustic signals in the brainstem. The subtypes of neurons, with whom they interconnect, the efficacy of those connections, and how the size an | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $109,964 | Grant | Trans-NIH Recovery Act Research Support: Cellular Mechanisms of Auditory Information Processing-ARRA This supplement requests funds to accelerate our research on the inhibitory neural circuits and changes due to hearing loss in the ventral cochlear nucleus of the auditory brainstem by adding an | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $255,060 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Adminstrative Supplement is to accelerate the discovery of novel genes for hereditary hearing impairment (HHI) in four highly informative Middle Eastern kindreds using next-generation sequencing technology. This effort derives directl | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ROCHESTER | $259,562 | Grant | Trans-NIH Recovery Act Research Support: The Administrative Supplement grant will help to accelerate our scientific discovery by ensuring sufficient personnel effort and purchasing urgently needed equipment, thereby accelerating the translation of these basic discoveries into the clinical applic | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| NORTHWESTERN UNIVERSITY | $259,531 | Grant | Trans-NIH Recovery Act Research Support: This project will help stimulate the economy by the hiring of a new researcher who has critical skills important for this research and by payment for testing of additional research subjects. With the payment to these people, we will accelerate the tempo o | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $175,968 | Grant | Trans-NIH Recovery Act Research Support: One of the major challenges in medicine is the rapid and accurate measurement of protein bio- markers, cells and organisms in different biological samples. During the prior funding period we had developed a broadly applicable, novel, point-of-care diagnos | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $21,641 | Grant | Trans-NIH Recovery Act Research Support: Summer undergraduate research experience in studies engineering a carbohydrate-biomaterial interface for control of Wnt signaling | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| UNIVERSITY OF WASHINGTON | $197,214 | Grant | Trans-NIH Recovery Act Research Support: (a) Scope of the overall project and anticipated contribution of the requested supplement. Summarize the activities that were included in the parent grant that encompass those proposed in the supplemental request. This section should include a descriptio | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $544,368 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to develop a radically new Computed Tomography (CT) system design that promises to provide superior dose-efficiency and decreased patient dose, improved spatial and temporal resolution, and artifact-free wide volume c | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS AT ARLINGTON | $130,195 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of both parent and supplemental grant is focused on addressing fibrotic tissue reactions to implanted biomaterials, which involve a series of cascaded events. The parent grant proposed that, by blocking upstream inflammatory responses usi | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| UNIVERSITY OF PITTSBURGH THE | $485,889 | Grant | Trans-NIH Recovery Act Research Support: This application was written in response to the NIH Announcement for the Availability of Recovery Act Funds for Competitive Revision Applications (NOT-OD-09-058). The experiments outlined in this application were designed to expand the scope of the specif | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $173,711 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement provides funding to support the following: (1) The hiring of one new graduate student researcher -- This supplement will fund two years of training for a biomedical engineering student pursuing an advanced degree with a focu | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| OAKLAND UNIVERSITY | $15,700 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this award is to study magnetic forces on electric currents in biological tissue, and to analyze and develop new imaging techniques that use these magneto-acoustic effects. In the last two decades, many researchers have proposed magnet | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| MICHIGAN STATE UNIVERSITY | $52,896 | Grant | Trans-NIH Recovery Act Research Support: Abstract Methylmercury (MeHg) is an environmental neurotoxicant that causes developmental and adult toxicity. Exposure results from eating MeHg-contaminated seafood and fresh water fish. Effects of lifetime exposure to low levels of MeHg as might occur by | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $331,030 | Grant | Trans-NIH Recovery Act Research Support: Exposure to short wave ultraviolet light has been demonstrated to be the causal factor in nonmelanoma skin cancers and a strong risk factor in melanomas. While human cells only use nucleotide excision repair to repair the UV-induced dipyrimidine DNA photo | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $175,767 | Grant | Trans-NIH Recovery Act Research Support: The award supplement (awarded September 19, 2009) is entitled ?Accelerating basic research through job creation and equipment purchase?. The award supports (1) a new postdoctoral fellow or research technician, (2) summer jobs for two experienced undergrad | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is to purchase a Singer RoTorHDA robot equipment specifically designed for high-throughput generic screens in S. cerevisiae. This will accelerate our ability to answer the questions put forth in Aim 3 of the parent grant. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $71,178 | Grant | Trans-NIH Recovery Act Research Support: This supplement stimulated employment and accelerated investigation into the characterization of the bacterial actin-like protein, ParM. ParM-dependent DNA segregation helps us understand how cytoskeletal ploymers organize. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $87,546 | Grant | Trans-NIH Recovery Act Research Support: The DACT1 mouse as a model for OEIS-Purpose: Building on the parent grant, this supplement, which was completed in 2010, supported an additional post-doctoral researcher. Goals: To use a set of specific genetically-engineered mouse lines to explore cross | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $416,397 | Grant | Trans-NIH Recovery Act Research Support: Our laboratory has provided a unique perspective of endothelial health, showing that argininosuccinate synthase (AS) of the citrulline-nitric oxide cycle must be functional to sustain nitric oxide (NO) production and to maintain cell viability. Since virt | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $238,616 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of this proposal is to elucidate the cellular basis for bone marrow failure (BMF) in X-linked Dyskeratosis Congenita (X-DC), an inherited disease characterized by early mortality due to aplastic anemia. X-DC is one of the main inhe | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $164,827 | Grant | Trans-NIH Recovery Act Research Support: Medical decision support tools are increasingly available on the Internet and are being used by lay persons as well as health care professionals. The goal of some of these tools is to provide an individualized prediction of future health care related even | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $125,000 | Grant | Trans-NIH Recovery Act Research Support: Our group specializes in the use of natural plant products as pharmacological probes for exploring nervous system function, especially as this relates to somatosensation (touch and temperature sensation) and pain. The present proposal exploits the use of | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ARIZONA STATE UNIVERSITY | $619,038 | Grant | Trans-NIH Recovery Act Research Support: Neuroscientists have long recognized the significance of using microelectrode arrays for recording extracellular potentials from populations of neurons, for which a number of such devices have been developed so far. However, current implantable microele | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTHEASTERN UNIVERSITY | $78,000 | Grant | Trans-NIH Recovery Act Research Support: Cross Frequency Intergration for Speech Recognition in bimodal hearing | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $107,339 | Grant | Trans-NIH Recovery Act Research Support: A 5-year plan is proposed that consists of career training and a research project to develop skills toward reaching the goal of becoming an independent researcher in cancer prevention and control. The proposed plan includes formal coursework and seminars | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $98,877 | Grant | Trans-NIH Recovery Act Research Support: According to the NIH State of the Science consensus statement, the three most frequently reported and under treated cancer-related symptoms are pain, fatigue, and depression As part of a Mentored Career Development Award (K07CA118576-01), we have design | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Approximately 140,000 Americans develop colorectal cancer and approximately 50,000 individuals die from the disease every year. Thus, prevention of colorectal cancer will save many Americans. Colorectal neoplasia is multifactorial in origin, and exogenous | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF WASHINGTON | $49,551 | Grant | Trans-NIH Recovery Act Research Support: Dendritic cells (DCs) maintain tolerance by disabling autoreactive T helper cells and generating regulatory T cells. In systemic lupus erythematosus (SLE), tolerance is broken through aberrant activation and homeostasis of DCs. In health, DCs discern self | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF WASHINGTON | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Each year, 9 million people are newly infected with Mycobacterium tuberculosis (MTb) and approximately 2 million die from MTb worldwide. MTb is particularly devastating in children, where dissemination and meningitis occur much more readily than in adul | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Pancreatic islet transplantation is a potential cure for Type I diabetes, a disease which afflicts nearly 2 million persons in the United States, making it the second most common chronic disease in young people. A major challenge is the protection of the | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| CONNECTICUT CHILDREN'S MEDICAL CENTER | $39,372 | Grant | Trans-NIH Recovery Act Research Support: The award is for the purchase of a flexiVent complete system with installation and training. Our research efforts described under the parent grant application # 1K08AI071918- 01A1 are designed to characterize the ability of specific components of breast m | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF PITTSBURGH THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this research project is to identify the molecular mechanisms by which estrogen preserves bone mass in order to permit the design of better therapies for osteoporosis. Osteoporosis is a major health problem in the elderly resulting in | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $41,278 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this research is to investigate the hypothesis that dysregulated expression and function of Beta Protein 1 contributes to breast cancer pathogenesis. Dr. Berg cloned a novel homeobox gene called BP 1 based upon its ability to repress h | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $49,628 | Grant | Trans-NIH Recovery Act Research Support: Kaposi's sarcoma (KS) is a multicellular, angiogenic tumor arising in the setting of immunosuppression, including AIDS and solid organ transplantation. Despite advances in AIDS therapy and prevention, KS remains the most common AIDS-associated malignancy | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $192,486 | Grant | Trans-NIH Recovery Act Research Support: Two related pilot projects are proposed to improve the capability of non-linear optical microscopy (NLOM), which has increasing application in biology. The first project will explore strategies to increase the tissue depth at which high quality images ca | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF ALASKA FAIRBANKS | $583,071 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the proposed COBRE-funded Center for Alaska Native Health Research (CANHR) is to achieve a permanent and sustainable research center at the University of Alaska Fairbanks (UAF) with the primary theme of investigating obesity and chroni | Health and Human Services, Department of / National Institutes of Health | 8/30/2009 |
| UNIVERSITY OF IDAHO | $903,503 | Grant | Trans-NIH Recovery Act Research Support: A major challenge for public health officials is predicting the outbreak of diseases. Zoonotic diseases are a particular challenge since little is known about the specific mechanisms behind host switching. For example, what abiotic factors increase the pr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MOUNT DESERT ISLAND BIOLOGICAL LABORATORY (INC) | $1,699,968 | Grant | Trans-NIH Recovery Act Research Support: The goal of the Maine IDeA Network of Biomedical Research Excellence (ME-INBRE) is to exploit the power of comparative functional genomics to discover important information about the genetic properties and function of genes of diverse species, and to expa | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WAKE FOREST UNIVERSITY | $107,904 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION: This is an application for a 2 year administrative supplement to provide technical support for 5 K08 GM083154-02. Funds are requested to retain a technician to maintain the productivity and accelerated pace of the research project. The appli | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $182,624 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Seeding Postdoctoral Innovators in Research and Education (SPIRE): The SPIRE program at the University of North Carolina at Chapel Hill received supplemental support through ARRA in order to develop a summer research program that will provide mento | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $168,970 | Grant | Trans-NIH Recovery Act Research Support: 'We are requesting a Recovery Act Administrative Supplement to augment the activities of our postdoctoral program, Training in Critical Education and Research Skills (TEACRS), which is funded through the Institutional Research and Academic Career Developm | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF ILLINOIS | $9,288 | Grant | Trans-NIH Recovery Act Research Support: This is an application requesting administrative supplement to a K22DE014847 grant entitled G?Genomic Predictors of Oral Premalignancy Progression. To facilitate our studies proposed in the parent grant, we propose to recruit summer student assistants. Th | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| THE VANDERBILT UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: To facilitate the efficient and effective conduct of the parent K23 Mentored Clinical Scientist Development Award that seeks to define the clinical and molecular epidemiology of community-associated methicilin-resistant Staphylococcus aureus (CA-MRSA) in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Project Summary: Impact of Automated Reporting of Kidney Function in the Veterans Affairs Healthcare System Chronic kidney disease (CKD) is a readily treatable but under-recognized condition that is common in the general population. Although easily dete | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ROCHESTER | $138,005 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this administrative supplement (to the Career Development Award) is to hire additional personnel to provide critical support in coordinating, collecting, and analyzing human and cat data, as well as to support the purchase of additiona | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CINCINNATI | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The aim of this NIMH Mentored Patient-Oriented Research Career Development Award application is to support my career objective to become an independent investigator specializing in the relationship between neurobiological mechanisms and clinical features | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $107,239 | Grant | Trans-NIH Recovery Act Research Support: The science of this proposal is well aligned with a focus topic identified by the NIMH; enhancing risk prediction through secondary data analysis. The risk prediction rule developed through K23MH082641 will be derived and internally validated at a single | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $45,714 | Grant | Trans-NIH Recovery Act Research Support: To reduce the burden of disability caused by stroke there is a need for better treatments that are available to more stroke victims. Mechanical thrombectomy is a procedure that is very effective at restoring blood flow in acute stroke patients. It has b | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $47,045 | Grant | Trans-NIH Recovery Act Research Support: This application for a Mentored Patient-Oriented Research Career Development Award (K23) is designed to provide the candidate with advanced skills needed to establish an independent program of research in the cognitive neuroscience of aging and dementia r | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Use of an administrative supplement to support 2 additional research nurses to enroll study subjects in ongoing work exploring neighborhood level characteristics influencing patterns of pneumococcal carriage in children. | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF FLORIDA | $53,765 | Grant | Trans-NIH Recovery Act Research Support: The objective of this Administrative Supplement is to broaden the translational and applied research activities of Dr. Johannes Vieweg and to support his continued service as a mentor for young investigators involved in patient-oriented research. In this | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $107,920 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement request to a parent K25 grant AG027785. I propose to perform imaging and image processing on a large number of postmortem brain samples in order to expand the computational atlas of the human hippocampus that I created | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $75,060 | Grant | Trans-NIH Recovery Act Research Support: Effective treatment of serious mental and cognitive conditions associated with early life and excessive drinking, which afflict growing numbers of humanity. demands greater scientific understanding of the impact that alcohol wields on brain function. The | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| NORTHWESTERN UNIVERSITY | $53,162 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will be used to support a research assistance who will provide assistance and progress to the project. | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF PITTSBURGH THE | $48,535 | Grant | Trans-NIH Recovery Act Research Support: Craniofacial and dental genetic disorders like CL/P constitute a significant public health burden. The parent grant focuses on enhancing our understanding of such complex traits by developing, implementing computationally, and applying in analyses, statis | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NORTHWESTERN UNIVERSITY | $90,000 | Grant | Trans-NIH Recovery Act Research Support: The aim of the K99/R00 award is to assist the grantee in the transition from postdoctoral fellow to independent investigator. The supplemental year of K99 funding will allow Dr. Lear to make additional progress in the scientific aims of the grant and in c | Health and Human Services, Department of / National Institutes of Health | 5/12/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $2,548,679 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to the Hollings Cancer Center's (HCC) recently awarded Cancer Center Support Grant (1 P30CA138313-01) will provide essential funding to support the start up package of a new physician scientist who will be critical to optimi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $288,217 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement for Accelerating the Science (ACC) is linked to a new equipment (EQ_Research Equipment for the Advancement of Science) request which together encompass activities from the aims of three Cores of the parent grant G?? Core A, | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| THE VANDERBILT UNIVERSITY | $294,381 | Grant | Trans-NIH Recovery Act Research Support: This application is for expansion of the Vanderbilt Digestive Disease Research Center (VDDRC) pilot and feasibility program for two years under the American Recovery and Reinvestment Act of 2009. The VDDRC is focused on the study of the molecular and cel | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| COLD SPRING HARBOR LABORATORY | $99,310 | Grant | Trans-NIH Recovery Act Research Support: Real-time PCR, also known as quantitative PCR (qPCR), is a highly sensitive and accurate technique for detection and precise quantitation of nucleic acids. This established technology is heavily used by the members of this Program Project, in application | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $328,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of the Parental NIH/NCI grant # 5P01CA077664-10 entitled? High Throughput Genetic Analysis of Bladder Cancer? proposal are to improve our understanding of the molecular genetic changes that drive bladder cancer progression as we develop | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $1,061,795 | Grant | Trans-NIH Recovery Act Research Support: Germinal center (GC) B-cell lymphomas are clinically and genetically heterogeneous disorders. The incidence of the most common GC B-cell lymphomas has increased dramatically in recent years, with a 50% rise in the last generation. The participants of this | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF ILLINOIS | $142,412 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this supplement is to conduct one additional longitudinal follow-up with an established cohort of participants, first identified and characterized in mid-adolescence, and recruited based on relative risk for cigarette smoking. This rel | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $84,242 | Grant | Trans-NIH Recovery Act Research Support: This laboratory has had a 15 year experience in providing summer fellowships to undergraduate premedical and science majors who has gone onto either medical school or graduate school after this experience. Accordingly, funds for four undergraduate premed | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF MASSACHUSETTS | $600,000 | Grant | Trans-NIH Recovery Act Research Support: As the AIDS pandemic continues, the emergence of HIV variants that are drug resistant is a therapeutic challenge. The nine FDA-approved HIV-1 protease inhibitors are currently the most potent of the anti-viral drugs in the treatment of HIV infected patien | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $1,345,395 | Grant | Trans-NIH Recovery Act Research Support: This proposal for supplementary funding, submitted under ARRA guidelines NOT-OD-09-058 (NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications) extends the scope of the parent Program Project grant. The overall effort c | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $132,126 | Grant | Trans-NIH Recovery Act Research Support: Despite the success of the Back-to-Sleep campaign, the sudden infant death syndrome (SIDS) remains the leading cause of postneonatal infant mortality in the United States today. The major discovery of this program project in the last cycle was that multip | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ALASKA FAIRBANKS | $680,194 | Grant | Trans-NIH Recovery Act Research Support: The Bioinformatics Core applies advanced information technology to help solve biological problems. These technologies are aimed at organizing biological data, analyzing the data, and facilitating its interpretation. Life science research needs information | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $383,801 | Grant | Trans-NIH Recovery Act Research Support: The Kansas IDeA Network of Biomedical Research Excellence (K-INBRE, first known as the K-BRIN) was established in 2001 as a network of 9 Kansas institutions of higher learning. Kansas falls into the bottom half of states receiving research funding from th | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $875,389 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to complete construction of our inhalation Core Facility that has been approved by NCRR and partially funded by NCRR. This includes completing the project construction; furnish the offices; epuip the laboratory to make i | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $927,220 | Grant | Trans-NIH Recovery Act Research Support: The ultimate goals of the stand-alone Center of Lipidomics and Pathobiology at the Medical University of South Carolina (MUSC) are to elucidate unique mechanisms of lipid-mediated pathobiology (e.g., in cancers, diabetes, fungal infections, neurodegenerat | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF LOUISVILLE | $192,104 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to provide 8-week summer research internship positions for local/regional high school and college undergraduate students. The recipients of the internships work with cancer investigators to obtain hands-on bench research expe | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF KENTUCKY | $445,313 | Grant | Trans-NIH Recovery Act Research Support: We propose to establish a viral synthesis core administered through our COBRE on the Molecular Basis of Human Disease. Viral vectors are increasingly being used in biomedical research for expression of genes in cells difficult to transfect, for the long-t | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| MONTANA STATE UNIVERSITY, INC | $988,856 | Grant | Trans-NIH Recovery Act Research Support: Coxiella burnetii is an obligate intracellular bacterial pathogen that causes a debilitating disease known as Q fever. To date there is no approved vaccine for Q fever in the US and there is a major need for new therapeutic approaches to this disease. Thu | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $499,999 | Grant | Trans-NIH Recovery Act Research Support: Science in a Culture of Mentoring Translational Supplement. This supplement provides funds to expand on a discovery made in part by a previous COBRE investigator to generate fully human monoclonal antibodies after vaccination. Our goals for the production | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| FOX CHASE CANCER CENTER | $49,999 | Grant | Trans-NIH Recovery Act Research Support: For the 100 years of its history, Fox Chase Cancer Center (FCCC) has been guided by a singular mission to reduce the burden of human cancer. Its 1904 hospital charter called for 'the study of the cause, treatment and prevention of cancer and for the disse | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| WAKE FOREST UNIVERSITY | $47,689 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award provides funding to support the Adoption of New Technologies for Remote Data Capture & Protocol Authoring (ADOPT) ARRA Program. ADOPT is an NCI initiative funded through ARRA. ADOPT is intended to improve the efficiency and effec | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $266,990 | Grant | Trans-NIH Recovery Act Research Support: The project description remains as defined in the project abstract. As of the starting date we have hired a full-time Senior Project Analyst, and a part-time Graduate Research Assistant. In addition, we are nearing completion of the optimization for two | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| HEALTH RESEARCH, INC. | $1,300,294 | Grant | Trans-NIH Recovery Act Research Support: The Roswell Park Cancer Institute (RPCI) has been continuously recognized as a Comprehensive Cancer Center since the NCI designation of such centers in 1974 and is now requesting continued federal support for the next five years. A free-standing research, | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The Ohio State University Comprehensive Cancer Center (OSUCCC) is currently in its 29th year as an NCI-designated CCC and is now requesting continued federal support for the next five years. The OSUCCC named its 4th Director, Michael A. Caligiuri, M.D. in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $301,637 | Grant | Trans-NIH Recovery Act Research Support: This supplement addresses the development and implementation of a new support service within the Biomedical imaging core of our comprehensive cancer center. It will allow us to implement support of novel imaging and physiologic modeling within translatio | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $50,001 | Grant | Trans-NIH Recovery Act Research Support: The University of Texas M. D. Anderson Cancer Center (MDACC) is a free-standing comprehensive cancer center within the University of Texas system. The mission of the MDACC is to eliminate cancer in Texas, the nation and the world through outstanding integ | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF ARIZONA | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement will fund the Associate Director of Clinical Research Shared Service, who will oversee day-to-day clinical trials operations at the Arizona Cancer Center, and a Computer Database Specialist Principal of Clinical Trails, who will be the pri | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $1,519,725 | Grant | Trans-NIH Recovery Act Research Support: This is an Adminstrative Supplement Award for the recruitment of new faculty in NCI Designated Cancer Center (P30) at the Moores UCSD Cancer Center, Universtiy of California San Diego. The fund is a two-year support to recruit a physician scientist who h | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $1,475,182 | Grant | Trans-NIH Recovery Act Research Support: This application is in response to the NCI ARRA RFA 'Request for New Faculty Supplemental Award.' The parent grant for this award is P30 CA44579. The University of Virginia Cancer Center seeks to recruit physician-scientists who can link its strengths in | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $1,363,286 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The University of Michigan Comprehensive Cancer Center (UMCCC) requests renewal of its core grant in support of Senior Leadership, Programs, and Shared Core Facilities. A core grant to support the UMCCC was initially a | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NORTHWESTERN UNIVERSITY | $1,485,341 | Grant | Trans-NIH Recovery Act Research Support: This supplement is for the recruitment of new faculty in NCI Designated Cancer Center (P30) and in Minority Serving Institutions funded through the U54 Comprehensive Minority Institution/ Cancer Center Partnership | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $1,507,208 | Grant | Trans-NIH Recovery Act Research Support: The Chao Family Comprehensive Cancer Center received a total award of $1,507,208 in supplemental ARRA funds to recruit one new FTE. We leveraged this award with commitments from our University and permission from HHS Office of Grants Administration to pro | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $1,367,974 | Grant | Trans-NIH Recovery Act Research Support: The University of Minnesota Cancer Center (UMCC) is a NCI-designated Comprehensive Cancer Center dedicated to cancer research, education, and patient care for the citizens of the state of Minnesota and surrounding region. Since the time of the first award | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NEW MEXICO | $1,264,145 | Grant | Trans-NIH Recovery Act Research Support: The Cancer Epidemiology and Prevention Program was formally established in 1973 when the New Mexico Tumor Registry joined with 6 other population-based tumor registries to form the NCI-SEER (Surveillance, Epidemiology and End Results) program. The NM SEER | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| BAYLOR COLLEGE OF MEDICINE | $160,358 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement: The intent of this supplemental request is to enhance the ability of the Dan L. Duncan Cancer Center (DLDCC) clinical investigators to enroll patients in clinical trials at an additional venue and provide support to a post-doct | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $625,561 | Grant | Trans-NIH Recovery Act Research Support: The Columbia University Diabetes & Endocrinology Research Center integrates basic and translational diabetes research with existing institutional centers of excellence in obesity, atherosclerosis and cardiovascular biology to advance NIDDK?s core mission | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| THE VANDERBILT UNIVERSITY | $347,442 | Grant | Trans-NIH Recovery Act Research Support: The Vanderbilt OG??Brien Center was funded to establish the Vanderbilt Mouse Kidney Physiology and Disease Center (MKPDC). By bringing together nephrologists, pathologists, histologists, cell and molecular biologists together with experts in renal cell-sp | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | $99,999 | Grant | Trans-NIH Recovery Act Research Support: The proposed Mental Retardation and Developmental Disabilities Research Center (MRDDRC) was established in 1990 and renewed in 1995 and 1999. It represents the collaboration of the Children's Hospital of Philadelphia and the University of Pennsylvania (Pe | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $199,997 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA competitive revision of P30-NR005043 Center for Nursing Outcomes Research. We seek to extend the scope of the parent grant to create a new interdisciplinary collaboration with the Cartographic Modeling Laboratory (CML) and investigators i | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF OREGON | $827,898 | Grant | Trans-NIH Recovery Act Research Support: Expansion and enhancement of database support required for the Zebrafish International Resource Center (ZIRC) to provide resources to the research community. Zebrafish is a premiere organism to study vertebrate development, physiology, behavior, genetics | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $927,630 | Grant | Trans-NIH Recovery Act Research Support: This application under the American Re-investment and Recovery Act is for an administrative supplement to Gene Library Resource for the Sea Urchin S. purpuratus, 5P40 RR015044. The proposed work is an extension of the original grant goals which include | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF MASSACHUSETTS | $216,123 | Grant | Trans-NIH Recovery Act Research Support: Microtubules are dynamic cytoskeletal polymers that are required for mitosis, organelle motility and the establishment and maintenance of cell form. The microtubule cytoskeleton is dramatically reorganized each cell cycle: the extensive interphase microtu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BOSTON BIOMEDICAL RESEARCH INSTITUTE, INC. | $339,011 | Grant | Trans-NIH Recovery Act Research Support: To investigate the role of the molecular motor, Myo1c, in hearing. The broad, long-range goal of this study is to determine the molecular mechanism of hearing and balance. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $45,692 | Grant | Trans-NIH Recovery Act Research Support: The pathways of iron acquisition in Mycobacterium tuberculsosis are being studied by first determining molecular interactions that are critical for the function of the iron transporter IrtAB, in transporting siderophores, including an understanding the e | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $176,824 | Grant | Trans-NIH Recovery Act Research Support: The main focus of the parent grant application is to understand the immunologic interactions that mediate the modulatory effects of this FDA-approved therapy, thereby uncovering important aspects of intrinsic immune regulation. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $83,640 | Grant | Trans-NIH Recovery Act Research Support: Maturation functions of the HSV-1 tegument. Herpes simplex virus (HSV) assembles an icosahedral capsid and packages this structure with the viral genome in the nucleus. It then has to exit the nucleus using a complex envelopment/de-envelopment pathway tha | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| KANSAS STATE UNIVERSITY | $83,415 | Grant | Trans-NIH Recovery Act Research Support: Ischemia/reperfusion (IR) induced intestinal damage occurs in wildtype mice but is surprisingly absent in Cr2-/- mice. This administrative supplement will examine the differential cytokine expression in the 2 strains of mice by Luminex analysis. Additiona | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| MESA TECH INTERNATIONAL, INC. | $82,460 | Grant | Trans-NIH Recovery Act Research Support: We are funded by NIAID to develop a hand-held, affordable and instrumentation-free nucleic acid dipstick device for rapid avian flu diagnosis that is capable of differentiating avian flu and flu-like diseases (e.g. Avian flu H5N1, Type A human flu, RSV an | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| EMORY UNIVERSITY | $178,250 | Grant | Trans-NIH Recovery Act Research Support: Determinants of T cell fate in transplantation tolerance The project supported by these ARRA funds is investigating new methods of inhibiting the immune-mediated rejection of transplanted organs. Transplantation is a cure for many end-stage organ disease | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $395,724 | Grant | Trans-NIH Recovery Act Research Support: Allergic asthma is the most common chronic disease of childhood in the United States. Asthma is also the number one cause of school absences in America. The role of indoor allergen exposure in homes and asthma development and morbidity has been extensivel | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $128,610 | Grant | Trans-NIH Recovery Act Research Support: The long-range goal of the parent grant is to elucidate the molecular mechanisms involved in the pathogenesis of S. Typhimurium-induced enteritis and the innate immune response of the intestinal mucosa to enteric pathogens. The objectives of the parent gr | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF MARYLAND | $200,000 | Grant | Trans-NIH Recovery Act Research Support: This is a student administrative supplement to provide support for an undergraduate to wok in the laboratory. This will provide the undergraduate student an opportunity to gain valuable research experience and training. The Bmi-1 Polycomb Group (PcG) ge | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| ILLINOIS INSTITUTE OF TECHNOLOGY | $15,000 | Grant | Trans-NIH Recovery Act Research Support: Summer undergraduate student supplement for muscular dystrophy research. | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $606,241 | Grant | Trans-NIH Recovery Act Research Support: The leading cause of disability in the U.S.is arthritis, affecting approximately 60% of those over 65 years of age. Biomedical treatments are limited in their ability to curb osteoarthritis (OA) disease progression and to eliminate pain and functional imp | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $347,760 | Grant | Trans-NIH Recovery Act Research Support: This project is currently in the process of seeking compettive bids for services on this grant, to begin ordering samples. This supplemental funding is to be used for deep sequencing of candidate genomic intervals that we have identified by GWAS in alopec | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| THOMAS JEFFERSON UNIVERSITY | $145,075 | Grant | Trans-NIH Recovery Act Research Support: Acccording with the AIMs of the Recovery Act Administrative Supplement, we will expand employment opportunities for postdoc fellows and predoc students which sorely missing, especially in the area of research focused on tumor microenviroment. Moreover, w | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF KENTUCKY | $318,752 | Grant | Trans-NIH Recovery Act Research Support: Prostate apoptosis response-4 protein (Par-4; also known as PAWR) is a leucine zipper domain protein that is conserved in vertebrates. During the previous funding period, we showed the core effector domain of Par-4 (amino acids 137-195, designated the SAC | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $4,316,803 | Grant | Trans-NIH Recovery Act Research Support: Premenopausal Hormone Levels and Risk of Breast Cancer ABSTRACT: This applications is a Competitive Revision to R01 CA67262, entitled 'Premenopausal Hormone Levels and Risk of Breast Cancer'. The parent grant funds the assessment of a range of premenopaus | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| WAKE FOREST UNIVERSITY | $135,601 | Grant | Trans-NIH Recovery Act Research Support: Oncolytic ElB-55K-mutant adenoviruses have entered phase III clinical trials. However, the basis for their selective replication in tumor cells is poorly understood. Work of this lab has shown that ElB-55K-mutant viruses selectively replicate in and kill | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $100,047 | Grant | Trans-NIH Recovery Act Research Support: Mutations in the alpha-actinin-4 gene ACTN4 cause an autosomal dominant form of focal and segmental glomerulosclerosis (FSGS). ACTN4-mediated FSGS is dominant, adult onset, and slowly progressive, suggesting subtle time and stress dependent alterations in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $510,182 | Grant | Trans-NIH Recovery Act Research Support: Acyl CoA: Synthetase Structure, Function and Regulation: AARA In response to NOT-OD-09-058: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications, we propose a Competitive Revision to the Parent Grant DK 59935: Acyl-Co | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHILDREN'S HOSPITAL | $39,625 | Grant | Trans-NIH Recovery Act Research Support: The diffuse neuroendocrine system includes pancreatic islets, gastrointestinal and respiratory neuroendocrine cells, thyroid C cells, adrenal medulla cells, and pituitary cells. They share common phenotypes and signaling pathways with neuronal cells. A se | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $93,563 | Grant | Trans-NIH Recovery Act Research Support: In chronic inflammation, the affected tissue undergoes an oxidative stress that exacerbates inflammation and contributes to tissue damage including DNA damage and cancer. One of the molecules regulating the cellular responses to oxidative stress is APE-1 | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | $19,656 | Grant | Trans-NIH Recovery Act Research Support: NIDDK Summer Research Experience Supplement to DK063070: Undergraduate Student Exiperiential Learning in Adipocyte Biology and Nutrition Research provides additional funding to support 1 summer undergraduate student for two summers to help accelerate the | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| WASHINGTON UNIVERSITY, THE | $30,865 | Grant | Trans-NIH Recovery Act Research Support: The mucosal immune system is a complex network of lymphoid compartments whose function is to protect against invading pathogens. The immune responses generated by the mucosal immune system must be tightly controlled, as inappropriate responses can damage | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| UNIVERSITY OF PITTSBURGH THE | $55,385 | Grant | Trans-NIH Recovery Act Research Support: This award is supplemental funding to enable the maintenance of a colony of musk shrews that are used in nausea/emesis research. Musk shrews (mouse-sized animals) are used for this line of work because common laboratory animals, including mice and rats, | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $31,872 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal for supplementary funding to support student summer research positions. This proposal is directed towards characterizing the proliferation and cell-cell adhesion effects of Cdx2 and will test the following hypothesis: Cdx2 inhibits co | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $101,640 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement to the parent R01 DK069769 grant Autoimmunity and Pathogenesis of Glomerulonephritis (GN). The project investigates factors responsible for progressive renal disease in Systemic Lupus Erythematosus (SLE) with special e | Health and Human Services, Department of / National Institutes of Health | 8/29/2009 |
| UNIVERSITY OF MASSACHUSETTS | $152,098 | Grant | Trans-NIH Recovery Act Research Support: One of the most important interventions for osteoporosis is prevention of bone loss. The main emphasis of prevention strategies has been on dietary calcium intake, however calcium by itself has limited efficacy.Thus, any component that can improve calcium | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| WOODS HOLE OCEANOGRAPHIC INSTITUTION | $296,928 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application is to establish an NIEHS/NSF Center for Oceans and Human Health in Woods Hole Massachusetts. This will be a multi-institutional Center, with a mission to be a focal point for research and communication on issues at the interse | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| THE VANDERBILT UNIVERSITY | $426,250 | Grant | Trans-NIH Recovery Act Research Support: Mechanisms of immunity to rotavirus, the major cause of dehydrating diarrhea in children, have proven elusive. Despite the fact the live attenuated vaccines induce protection against severe disease, we still donG??t understand fully how immunity to rotavi | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $401,781 | Grant | Trans-NIH Recovery Act Research Support: Gram-negative pathogens cause a variety of diseases and present a significant strain to the US health care system. Many Gram-negatives rely on a molecular syringe to inject toxic proteins into host cells; therefore blocking the syringe could be an effecti | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $365,699 | Grant | Trans-NIH Recovery Act Research Support: Although there are significant and longstanding racial disparities in sexually transmitted infections (STI) among young women, their causal mechanisms are unidentified. Unprotected sex, concurrency, and partner choice are well established risk factors, bu | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TENNESSEE | $365,000 | Grant | Trans-NIH Recovery Act Research Support: Antimicrobial peptide resistance in Campylobacter. Campylobacter jejuni is the leading bacterial cause of human enteritis in the United States. Contaminated poultry meats are considered a significant source for human Campylobacter infections. Increasing | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF TOLEDO, THE | $360,565 | Grant | Trans-NIH Recovery Act Research Support: Interferons (IFNs) are multifunctional cytokines that play a critical role in innate immunity. Type I IFNs exhibit immunomodulatory, antiproliferative and antiviral activities, although gene knockout experiments have suggested that, among these effects, | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| CEDARS-SINAI MEDICAL CENTER | $377,850 | Grant | Trans-NIH Recovery Act Research Support: This exploratory proposal by a new investigator aims to develop a novel multiphoton fluorescence lifetime imaging system with a focus on non-invasive, early detection of primary tumors invivo in mouse models. These findings will pave a way for monitoring | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $365,200 | Grant | Trans-NIH Recovery Act Research Support: Malignant gliomas are among the most fatal cancers. Microglia (MG) and macrophages (MP) represent a significant component of the brain response to malignant brain tumors.Although the exact contribution of these cells to the tumor microenvironment is uncle | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $371,635 | Grant | Trans-NIH Recovery Act Research Support: Pancreatic cancer is a serious health problem. In the United States alone, nearly 35,000 new cases are diagnosed annually and about same number of patients die of the disease. Difficulty in early diagnosis, rapid metastasis and intrinsic resistance to kno | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| NEW YORK UNIVERSITY (INC) | $599,672 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to the parent grant of the NYU Center for the Study of Asian American Health (CSAAH) will provide support to establish an innovative and national scientific partnership with CSAAH, the Asian & Pacific Islander American Heal | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $261,904 | Grant | Trans-NIH Recovery Act Research Support: Tumor cells hijack long-silenced developmental programs that allow growth, invasion, and metastasis. The Hedgehog pathway is one such developmental pathway that is damaged in a variety of cancers. We strive to obtain a detailed biochemical understandin | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $60,235 | Grant | Trans-NIH Recovery Act Research Support: Taste transduction begins when sapid stimuli interact with the apical membrane of receptor cells, causing an increase in intracellular Ca 2+. This ultimately results in release of transmitter and activation of gustatory afferent fibers. Several G protein- | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| NORTHEASTERN OHIO UNIVERSITY COLLEGE OF MEDICINE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to provide needed equipment to support NIH-funded research. The awarded equipment will advance the quality and pace of scientific discovery under the parent award. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| HOUSE RESEARCH INSTITUTE | $193,269 | Grant | Trans-NIH Recovery Act Research Support: The major purpose of this supplement project is to accelerate our scientific findings by increasing our capability to test subjects from rare patient groups when they become available. With the current staffing level and potentially eight referring physi | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| GEORGETOWN UNIVERSITY (THE) | $10,131 | Grant | Trans-NIH Recovery Act Research Support: This supplement will support an summer intern who will carry out experiments related to Aim #3: Test the hypothesis that RAG1 ubiquitin ligase activity/ubiquitylation promotes V(D)J recombination in cells and that ubiquitylation modulates RAG1?s other bi | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $26,650 | Grant | Trans-NIH Recovery Act Research Support: There is a crucial need for the development of new strategies that would achieve transplantation tolerance without the deleterious side effects of drug-mediated immunosuppression. Assessing potential alternatives, we have established that the transfer of | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF IOWA, THE | $38,962 | Grant | Trans-NIH Recovery Act Research Support: Respiratory syncytial virus (RSV) is the leading cause of viral lower respiratory tract infection in infants and young children. In addition, RSV causes serious disease in elderly and immune compromised individuals. Immunization against RSV is associated | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| HEALTH RESEARCH, INC. | $52,190 | Grant | Trans-NIH Recovery Act Research Support: To date, no single vaccine strategy is capable of eliciting the entire spectrum of immune responses deemed necessary for an effective HIV vaccine. The long-term goal of this study is to develop a new platform for creating recombinant vaccines, using a tar | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON | $422,566 | Grant | Trans-NIH Recovery Act Research Support: In work supported by the parent grant, we have identified the Th1-associated transcription factor T-bet as a key controller of the proliferation and surivival of Foxp3+ regulatory T cells during type-1 inflammation. The proposed supplement will support o | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DUKE UNIVERSITY | $75,435 | Grant | Trans-NIH Recovery Act Research Support: Since this application was submitted in 2006, the 2D-PAGE proteomic methodologies proposed to define the biology of Lipid Droplets have been surpassed by far more sensitive and comprehensive tandem MS/MS approaches. These new machines and technologies are | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | $794,775 | Grant | Trans-NIH Recovery Act Research Support: It is now clear that SLE, like other autoimmune diseases, develops in the genetically predisposed host and begins with a lengthy period during which autoreactivity is apparent, but there is no evident tissue damage. The period can continue for years and | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $109,145 | Grant | Trans-NIH Recovery Act Research Support: The Role of Dendritic Cells and Macrophages in Systemic Lupus Erythematosus - AR-Minority Supplement for Shannon Jones on grant 5 R01 AI070984. Abstract of 5 R01 AI070984 Defects in the regulation of innate immune responses are implicated in autoimmune di | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $345,879 | Grant | Trans-NIH Recovery Act Research Support: Mechanism/predictors of gential/rectal HIV shedding during ART w/plasma <50c/mL -- Antiretroviral drugs have radically modified the course of HIV-1 disease among individuals with access to these chemotherapeutics. The selection of drug-resistant | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $420,454 | Grant | Trans-NIH Recovery Act Research Support: Pathogenic eukaryotes in the phylum Apicomplexa include some of the most notorious protozoan parasites, such as Plasmodium (malaria), Cryptosporidium (diarrheal disease), and Toxoplasma (toxoplasmic encephalitis). The latter two parasites have recently be | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $729,029 | Grant | Trans-NIH Recovery Act Research Support: Award Name: New Approaches to Dementia Heterogeneity. This revision to the UCSF Alzheimers Disease Research Center (ADRC) Data Management and Statistics (DMS) core proposes accelerated development of comprehensive data management for the neuropathology c | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $184,000 | Grant | Trans-NIH Recovery Act Research Support: The requested supplement is to further address selected Hypotheses and Aims of the parent grant. This will be done by analyzing in more detail samples of bovine and equine SF that have already been procured and that have been, or are being, analyzed under | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF CONNECTICUT | $266,726 | Grant | Trans-NIH Recovery Act Research Support: Muscle injury stimulates normally quiescent muscle satellite cells to re-enter the cell cycle and execute the myogenic program, resulting in the restoration of muscle structure and function. While the essential function of satellite cells in muscle repair | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF IOWA, THE | $893,569 | Grant | Trans-NIH Recovery Act Research Support: Rheumatoid arthritis (RA) remains a major unmet medical need despite recent advances in therapy. The pain and loss of function resulting from chronic synovitis are due to a variety of influences, including activated adaptive and innate immune responses. I | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $143,372 | Grant | Trans-NIH Recovery Act Research Support: Myotonic muscular dystrophy type 1 (DM1) and type 2 (DM2) are caused by a toxic gain of function by expanded repeating RNAs. Both expanded repeats reside in noncoding regions and bind to the splicing regulator muscleblind (MBNL1); the formation of the RNA | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $242,176 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to elucidate the genetic networks that direct cell invasion through basement membranes, the dense, sheet-like extracellular matrix that surrounds most tissues. The mechanisms that cells employ to cross basement membranes in vivo rema | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| J.DAVID GLADSTONE INSTITUTES, THE | $370,985 | Grant | Trans-NIH Recovery Act Research Support: Pathway-oriented visualization of genomic information enables biologists to interpret data in the context of biological processes and systems. We developed GenMAPP (Gene Map Annotator and Pathway Profiler) as a free, open-source, stand-alone computer prog | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| HEALTH RESEARCH, INC. | $355,540 | Grant | Trans-NIH Recovery Act Research Support: Ricin is an extremely poisonous plant-derived toxin that is considered a potential biothreat agent. The Centers for Disease Control has classified ricin as a Category B agent and the National Institutes of Health has deemed the development of countermeas | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $504,400 | Grant | Trans-NIH Recovery Act Research Support: Most of our successes in controlling viral disease in the human population have been based upon live, replicating viruses. Live vaccinia virus (the original vaccine) was used to end smallpox epidemics. Poliomyelitis, mumps, measles, rubella, and chickenpo | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| INFECTIOUS DISEASE RESEARCH INSTITUTE | $432,300 | Grant | Trans-NIH Recovery Act Research Support: Mycobacterium tuberculosis is a major human pathogen causing significant human suffering worldwide. As the leading cause of death from a single bacterial infection, it is imperative to understand the biology, physiology and pathogenicity of the organism. | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $405,580 | Grant | Trans-NIH Recovery Act Research Support: The Rev-RRE interaction and the subsequent transport of intron-containing viral mRNA mediated by the cellular export receptor CRM1 are essential to the replication of the HIV-1 retrovirus. The current model for oligomeric Rev binding to its cognate RRE is | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $388,851 | Grant | Trans-NIH Recovery Act Research Support: Brain metastases are an important limiting factor in the successful treatment of patients with non-small cell lung cancer (NSCLC). Despite the standard use of whole brain radiotherapy (WBRT), the prognosis of patients with brain metastases remains dismal. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $356,950 | Grant | Trans-NIH Recovery Act Research Support: This proposal is to isolate T cell clones bearing high affinity T cells receptors (TCR) reactive with prostate specific membrane antigen (PSMA) and prostate stem cell antigen (PSCA) and to characterize their efficacy after engineering them on normal perip | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $377,520 | Grant | Trans-NIH Recovery Act Research Support: Anorexia-cachexia occurs because detection of energy deficit by the brain becomes impaired due to cytokine excess. The arcuate neuropeptide Y (NPY) neurons normally activate anabolic processes during energy deficit in order to restore energy homeostasis. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $351,964 | Grant | Trans-NIH Recovery Act Research Support: Proton radiotherapy is growing in the US and around the world. This growth is due to the commercial availability of protons and the physical advantages of the improved ability to deposit most of the radiation dose in the tumor, as opposed to x-rays where | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| NEW YORK UNIVERSITY (INC) | $220,835 | Grant | Trans-NIH Recovery Act Research Support: P-type ATPases constitute a large family of ATP-dependent ion transporters present in all kingdoms of life. Members of this family are generally responsible for maintaining ionic homeostasis and for priming cells for essential activities such as muscle c | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $193,633 | Grant | Trans-NIH Recovery Act Research Support: Cyclin-dependent kinases (CDKs) control cell division and transcription by RNA polymerase II (Pol II), and are themselves stringently regulated. An activator common to both cell-cycle and transcription pathways in metazoans is the CDK-activating kinase (C | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $238,719 | Grant | Trans-NIH Recovery Act Research Support: The proposed research will focus on a broad set of aims that center around the development and application of the nickel-catalyzed, silane-promoted reductive coupling of aldehydes and alkynes to generate allylic alcohols. Allylic alcohols are a common str | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $224,769 | Grant | Trans-NIH Recovery Act Research Support: Increases in cytoplasmic Ca2+ evoked by inositol(1,4,5)-trisphosphate receptors (IP3Rs) regulate many physiological events. Dysfunction of the IP3-stimulated Ca2+ release pathway is involved in neurodegenerative and neurological disease, as well as exocri | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $178,291 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent grant is to identify factors involved in the increase in food intake and negative energy balance and determine their functional role in the suppression of GnRH/LH secretion during lactation. However, this research has broade | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $107,020 | Grant | Trans-NIH Recovery Act Research Support: The broad aim of this research plan is to investigate developmental mechanisms involved in the early diversification of motoneurons within or originating from the lumbosacral (LS) spinal cord. Specific aims call for an investigation of the roles of Hox tr | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $426,375 | Grant | Trans-NIH Recovery Act Research Support: Our long-range goal is to understand the pathogenesis of infections with Non-typhoidal Salmonella serotypes (NTS) in HIV patients. The objectives of this application are to investigate mechanisms resulting in a synergy between these pathogens during co-in | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $453,750 | Grant | Trans-NIH Recovery Act Research Support: Bacillus anthracis is a Gram-positive, endospore-forming pathogen, which causes lethal inhalation anthrax in humans. It has also gained recent notoriety as a potential biothreat weapon. A hallmark of B. anthracis is the presence of two large plasmids pXO1 | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| SAN DIEGO STATE UNIVERSTIY FOUNDATION | $406,175 | Grant | Trans-NIH Recovery Act Research Support: Activation of thymus-derived (T) lymphocytes is critical in the immune response to pathogens, autoimmunity, and in allergic responses. Activation of T cells through their anitgen receptors (TCR) involves a complex process of biochemical events critically | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $412,500 | Grant | Trans-NIH Recovery Act Research Support: In this R21 application, we propose to test our hypothesis with the following specific aims using a murine model of allergic asthma: In Aim 1, we determine whether mice deficient in Muc1 expression fail to develop the type-2 immune response associated wit | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $412,500 | Grant | Trans-NIH Recovery Act Research Support: Cats are uniquely poised to serve as reservoirs and potential `mixing vessels' for influenza viruses given their interaction within the environment of humans, wildlife, birds, and farm animals. However, cats have been overlooked as a potential reservoir b | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ROCHESTER | $422,250 | Grant | Trans-NIH Recovery Act Research Support: Influenza is a globally important respiratory pathogen that causes nearly annual epidemics and occasional pandemics. Recent spread of highly pathogenic avian influenza H5N1 viruses is a new threat that may lead to a deadly influenza pandemic. Influenza an | Health and Human Services, Department of / National Institutes of Health | 5/04/2009 |
| NORTHWESTERN UNIVERSITY | $264,191 | Grant | Trans-NIH Recovery Act Research Support: Ikaros is a nuclear protein and key regulator of T lymphopoiesis. Ikaros deficiency in mice results in abnormal T cell development and, with 100% penetrance, T cell leukemogenesis. However, the mechanistic role of Ikaros in these events is not yet known. | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| STEVENS INSTITUTE OF TECHNOLOGY (INC) | $423,643 | Grant | Trans-NIH Recovery Act Research Support: Bacteria in biofilm show unique physiological characteristics that are much different from planktonic cultured phenotypes. One of the most important features of bacterial biofilms is their resistance to antimicrobial agents and the host immune system atta | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF KENTUCKY | $379,470 | Grant | Trans-NIH Recovery Act Research Support: Emergence of new viruses is a continuing threat to our society. Evolution of plus- stranded RNA viruses is frequently driven by RNA recombination, a process that joins noncontiguous RNA segments together, creating novel combinations of genes or regulatory | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $522,225 | Grant | Trans-NIH Recovery Act Research Support: Pseudomonas aeruginosa is a common environmental microorganism; most prominent is the role of P. aeruginosa in patients suffering from cystic fibrosis, as lung defense functions are impaired. Importantly, a molecular mechanism underlies P. aeruginosa path | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| SALK INSTITUTE FOR BLOGICAL STUDIES | $526,625 | Grant | Trans-NIH Recovery Act Research Support: Host cell pathways are harnessed and inactivated by viruses during productive infection. In vitro replication systems have been useful for studying viral DNA replication mechanisms, but they fail to capture the full complexity of the cellular environment | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $385,000 | Grant | Trans-NIH Recovery Act Research Support: Cholera is an acute water-borne diarrheal disease caused by Vibrio cholerae of serogroups O1 and O139. The bacterium is transmitted person-to-person by the fecal oral route. Infecting Vibrios that overcome the gastric acid barrier swim toward and adhere t | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $485,756 | Grant | Trans-NIH Recovery Act Research Support: Substance Abuse Treatment for Chronic Pain Patients on Opioid Therapy Project Summary Prescription opioids are believed to be the most commonly abused drugs in the United States, and misuse of prescription opioids is prominent among the chronic pain popul | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| NEW YORK UNIVERSITY | $1,125,680 | Grant | Trans-NIH Recovery Act Research Support: The abuse of illicit drugs such as cocaine and MDMA inflicts tremendous damage on society. The proposed research plan is aimed at characterizing the neural correlates of the engagement level and effectiveness of different substance abuse prevention messag | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| BAYLOR COLLEGE OF MEDICINE | $421,982 | Grant | Trans-NIH Recovery Act Research Support: 'Medication development for MA dependence. abstract:N-acetyl-l-cysteine (NAC) treatment is associated with reduced susceptibility to reinstatement of cocaine-seeking behavior in rats (Baker et al 2002) and with reduced cue-induced craving in cocaine-depen | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| THE CHILDRENS HOSPITAL LOS ANGELES | $286,398 | Grant | Trans-NIH Recovery Act Research Support: Despite recent literature demonstrating the clinical efficacy of immersive virtual reality (VR) for pain reduction in pediatric and adult research settings, the neurobiological mechanisms underlying VRG??s action remain enigmatic. This study aims to furth | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF NEW MEXICO | $403,810 | Grant | Trans-NIH Recovery Act Research Support: Motivational Interviewing (MI) is a directive, client-centered therapeutic method employed in the treatment of substance abuse. Despite strong empirical support for MI in substance abuse treatment, it has been difficult to determine why MI is effective. O | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $420,750 | Grant | Trans-NIH Recovery Act Research Support: The offspring of smokers display attentional and cognitive deficits and impaired learning and memory, but little is known about the potential mechanisms of these effects. During early postnatal development, GABAergic interneurons play a critical role in n | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| KENNESAW STATE UNIVERSITY | $367,820 | Grant | Trans-NIH Recovery Act Research Support: Although drug use and HIV rates among older drug users are increasing at alarming rates, knowledge on drug use patterns and risk behaviors among this cohort as older adults is limited. National trend data show that adults who are 45 or older comprise the | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| BROAD INSTITUTE, INC., THE | $657,600 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic modifications have been recognized as important factors in modification of gene expression levels, specification of cellular state and developmental potential, and etiology of cancer. In particular, post- translational modifications to histone | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF WASHINGTON | $423,436 | Grant | Trans-NIH Recovery Act Research Support: For the last several years my laboratory has studied the neurochemical changes that take place in the neonatal rat spinal cord following repeated opiate administration as a cellular model of opiate analgesic tolerance. We have reported increases in NMDA | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UTAH STATE UNIVERSITY | $374,944 | Grant | Trans-NIH Recovery Act Research Support: Title: Behavioral Momentum of Cocaine Self-Administration (1R21DA026497-01) The persistent nature of drug seeking and the tendency to relapse are defining features of drug abuse. Cues associated with using drugs are thought to play a critical role in the | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $467,500 | Grant | Trans-NIH Recovery Act Research Support: Patients with chronic liver disease frequently progress to fibrosis and finally cirrhosis. Cirrhosis is the most important determinant of liver-related mortality. At present there exists no proven therapy to halt fibrosis progression or to reverse cirrhos | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $413,535 | Grant | Trans-NIH Recovery Act Research Support: This research project involves studying naturally occurring IgM autoantibodies that bind to leucocytes (IgM-ALA). Hypothesis: We propose that IgM-ALA provide an innate mechanism to inhibit inflammatory processes as for example that observed in many kidney | Health and Human Services, Department of / National Institutes of Health | 6/22/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $402,268 | Grant | Trans-NIH Recovery Act Research Support: Our aim is to exploit newly developed device and material technologies to build drug delivery devices for urological indications. We will demonstrate devices to replace intravesical therapies that require frequent instillations of drug solutions into the | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $400,883 | Grant | Trans-NIH Recovery Act Research Support: Our goal in this proposal is to identify and understand the cellular components that internalize and transport endocytic cargo from the apical plasma membrane to the lysosomes of intestinal epithelial cells (enterocytes). Many epithelial cell surface rece | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| MICHIGAN STATE UNIVERSITY | $400,568 | Grant | Trans-NIH Recovery Act Research Support: Electrochemical methods with diamond microelectrodes will be used to investigate neuronal signaling pathways in the gut wall. These methods provide a direct measure of local concentration changes of electroactive neurotransmitters near the sites of releas | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| ILLINOIS STATE UNIVERSITY | $376,081 | Grant | Trans-NIH Recovery Act Research Support: The sodium-potassium adenosine triphosphatase (i.e. Na,K-ATPase) is responsible for controlling cellular fluid and electrolyte balance in higher eukaryotes. The An,K-ATPase is a heterodimeric integral membrane protein consisting a catalytic a-subunit (~1 | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $411,228 | Grant | Trans-NIH Recovery Act Research Support: Title: 'Microfabricated Biosensor Platform for Monitoring of Cell Metabolism' Liver is the metabolic center of human body and is largely responsible for detoxification and energy regulation functions. Energy regulation refers to the program of consumptio | Health and Human Services, Department of / National Institutes of Health | 5/08/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $412,139 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project is to develop new modalities of functional imaging in living tissues. To reach this goal we will use a new concept of Variable Field (VF) and Variable Radio Frequency (VRF) proton electron double resonance imaging (PEDRI) | Health and Human Services, Department of / National Institutes of Health | 5/06/2009 |
| UNIVERSITY OF TEXAS AT DALLAS | $394,049 | Grant | Trans-NIH Recovery Act Research Support: Intracellular imaging and targeted delivery demand new nanomaterials that can directly cross cell membranes and enter the cytosol without being encapsulated by membrane bound vesicles. We recently found that highly luminescent, gold nanoparticles about 2 | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $377,960 | Grant | Trans-NIH Recovery Act Research Support: MECHANISMS OF XENOESTROGEN STRESS: A PROTEOMIC AND FUNCTIONAL GENOMIC APPROACH Xenoestrogens interfere with normal endocrine functioning and have been linked to reproductive and developmental abnormalities in wildlife species and causally associated with | Health and Human Services, Department of / National Institutes of Health | 5/19/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $159,819 | Grant | Trans-NIH Recovery Act Research Support: Bioinorganic Copper Coordination Chemistry - (i) obtain an advanced piece of equipment and to (ii) (ii) obtain salary support for a currently advanced postdoctoral associate who will carry out research using this equipment. Thus, the requests are integral | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| DUKE UNIVERSITY | $221,402 | Grant | Trans-NIH Recovery Act Research Support: The biological functions of DNA, including replication, transcription, recombination and repair, require unwinding and rewinding of the intertwined duplex. DNA topoisomerases are the essential enzymes to facilitate these processes. Besides their ubiquitou | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $94,387 | Grant | Trans-NIH Recovery Act Research Support: The proposed research is a continued study of the involvement of proteins in splicing group I and II introns. These introns use RNA-catalyzed splicing mechanisms, but require proteins to help fold the intrpn RNA into the catalyti- cally active structure. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF UTAH, THE | $108,992 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Studies of the yeast HO gene have identified many important transcriptional regulators and also identified regulatory paradigms that are conserved in metazoans. Activation at HO involves the sequential recruitment of t | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $99,964 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to replace an aging (~20 yrs old) circular dichroism (CD) spectropolarimeter, an integral component of a larger magnetic (M) CD instrument. The instrument is heavily used by students and postdocs to study non-heme iron si | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF WASHINGTON | $154,481 | Grant | Trans-NIH Recovery Act Research Support: This a supplemental request to develop the second phase of a database program that provides easy access to 500,000 image files in a convenient format on our web page for scientists studying pattern recognition. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $242,327 | Grant | Trans-NIH Recovery Act Research Support: This project is designed to explore a novel approach to seeking new classes of antibiotics against the tuberculosis bacterium, Mycobacterium tuberculosis, and new classes of blood thinners for humans that could be more effective than the most common antic | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF ARIZONA | $49,533 | Grant | Trans-NIH Recovery Act Research Support: Protein aggregation resulting from stress, disease or mutation poses a major threat to all cells. Consequently, cells have developed mechanisms of protein quality control involving specific proteases and molecular chaperones that prevent or resolve prote | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $347,112 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of the parent grant is to understand the regulation of telomerase in baker's yeast. We wish to extend the original aims of this grant to the analysis of telomerase in a second model system, the fission yeast, S. pombe. Thus, we are requ | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| BRANDEIS UNIVERSITY | $77,184 | Grant | Trans-NIH Recovery Act Research Support: The chemistry catalyzed by cytochromes P450 (activation of molecular oxygen to react with organic molecules) is inherently hazardous to the organism, and must be tightly regulated or take place in a controlled environment. Structural and dynamic changes t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HEALTH RESEARCH, INC. | $276,990 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Homing endonucleases are rare-cutting DNA cleavage enzymes that are most often encoded by introns and inteins. Intron endonucleases and inteins attract considerable attention for their molecular mechanisms, phylogeneti | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $74,037 | Grant | Trans-NIH Recovery Act Research Support: This submission is in response to Notice Number NOT-OD-09-058 entitled: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. Control of gene expression is essential for normal development, and many diseases can be at | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $117,773 | Grant | Trans-NIH Recovery Act Research Support: The proposed project for this administrative supplement is aimed at retaining and hiring expert individuals to drive progress on three specific projects approved in the parent grant. The three projects are 1) determination of the function of separase in | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $182,339 | Grant | Trans-NIH Recovery Act Research Support: Heterotrimeric G proteins are activated by membrane receptors that respond to a diverse set of agonists ranging from hormones, ions, light and neurotransmitters. Activated G proteins in turn can activate a host of intracellular effector proteins, one of w | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF UTAH, THE | $65,451 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The basic molecular machinery controlling mitochondrial fission is conserved from yeast to humans. We are using genetic, biochemical and structural approaches to understand the mechanism of mitochondrial fission in bud | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF OKLAHOMA | $121,159 | Grant | Trans-NIH Recovery Act Research Support: The siderophore ferric enterobactin (FeEnt) enters Escherichia coli through the FepA protein of the outer membrane. The FeEnt transport process is a high affinity, multi-component, energy dependent reaction that is prototypic of iron uptake systems in Gra | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $87,314 | Grant | Trans-NIH Recovery Act Research Support: This subaward to the R01 entitled Dynamics and Mechanics of Mitosis in Drosophila is aimed at characterizing the homotetramer domain of the kinesin5, KLP61F, a motor protein playing a central role in mitosis. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $186,197 | Grant | Trans-NIH Recovery Act Research Support: This funding supplement will create one new full-time job; allow retention of an existing employee at a fulltime level; provide training for a Doctor of Science student; and allow purchase of lab supplies to support this new research. The long-term goal o | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $209,342 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this ARRA supplement to grant GM056890 is to accelerate progress on Aims 1 and 2 of GM056890 (April 1, 2008-March 31, 2012). The Aims of the parent grant, GM056890, are to define the principles by which distinct protein-protein and DNA-pro | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $30,386 | Grant | Trans-NIH Recovery Act Research Support: The funds requested will be used to purchase a Tecan Infinite M200 Fluorescence plate reader with shaking platform and temperature control. This highly versatile instrument will enhance our abilities to fulfill all three aims of our current NIH R01 grant | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $125,161 | Grant | Trans-NIH Recovery Act Research Support: FtsZ, a homolog of tubulin, is the major cytoskeletal protein in bacterial cell division. It assembles into protofilaments that are ~30 subunits (120 nm) long. In vivo these protofilaments are further assembled into a Z ring, which encircles the cell at m | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| NEW YORK UNIVERSITY (INC) | $219,700 | Grant | Trans-NIH Recovery Act Research Support: Research during the past two decades has suggested that the retinoblastoma tumor suppressor (pRB) and two related proteins (p107 and p130; collectively referred to as pocket proteins) play a fundamental role in regulating the cell cycle, and pRB has been | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. | $150,053 | Grant | Trans-NIH Recovery Act Research Support: The dorsoventral axis of the Drosophila embryo is established by ventral activation of the Toll signaling pathway, resulting in the graded nuclear uptake of the Dorsal transcription factor. Pathway activation relies on a ventral cue synthesized during oog | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $165,402 | Grant | Trans-NIH Recovery Act Research Support: Comparisons of the genomes from humans and lower organisms reveal that the complexity in humans is achieved not by a dramatic increase in the number of genes but by alternative splicing events that stitch together different portions of genes to generate d | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $216,178 | Grant | Trans-NIH Recovery Act Research Support: FtsZ is an essential tubulin-like GTPase that assembles into a ring structure at the site of cell division and recruits other essential division proteins to form the septal ring critical for bacterial cytokinesis. FtsZ is widely conserved in the Bacterial | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $131,060 | Grant | Trans-NIH Recovery Act Research Support: The broad goal of the parent grants research is to learn how the Hsp70 chaperone modifies the intrinsic solution conformation of its substrates thereby gaining insights into how Hsp70 promotes protein folding and prevents protein aggregation. U | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $210,600 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to accelerate and strengthen the studies described in the parent grant, which are directed towards the understanding of the metabolism and function of the amyloid-? precursor protein (APP), a protein highly relevant to the pat | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $356,200 | Grant | Trans-NIH Recovery Act Research Support: This application is for an administrative supplement to parent grant RO1 GM068636. The supplement requests funds for a post-doctoral fellow (Savithamani Kulandaivel (100%), and part time support for a Research Associate (Grace Enfield) (40%), and for equ | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $229,035 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The long-term goal of our studies is to understand how prostaglandin (PG) synthesis is regulated. There are two PGH synthases (PGHS-1 and -2) each able to catalyze the committed step in PG formation-oxygenation of the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE WASHINGTON UNIVERSITY | $70,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to enable the investigation of the salvation and electrostatic properties of macromolecules in biomedical research by supporting the maintenance and continued development of the open-source Adaptive Poisson- Boltzmann Solver an | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MICHIGAN STATE UNIVERSITY | $70,000 | Grant | Trans-NIH Recovery Act Research Support: We request funding to purchase a surface plasmon resonance (SPR) instrument in support of our ongoing mechanistic studies of catalytic RNA molecules including the hairpin ribozyme. A key step in the reaction mechanism of the hairpin is the docking transi | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE WASHINGTON UNIVERSITY | $101,171 | Grant | Trans-NIH Recovery Act Research Support: Septins were discovered as mutants defective in cell division in budding yeast. Septins form filaments and compose a ring at the neck between mother and bud. Septins function as a diffusion barrier for mother / bud polarity and as a scaffold for regulator | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $75,937 | Grant | Trans-NIH Recovery Act Research Support: The proposed research is focused on the structure and function of the Na+-pumping NADH:quinone oxidoreductase (Na+-NQR) from Vibrio cholerae. This enzyme is the primary gateway for electrons into the aerobic respiratory chain of many marine and pathogenic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NORTHWESTERN UNIVERSITY | $51,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement will be used for equipment that will accelerate the pace of research pn particulate methane monooxygenase(pMMO). | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $77,559 | Grant | Trans-NIH Recovery Act Research Support: There are two expected outcomes. First, we expect to attain a greater understanding of the molecular mechanism of the nicotinic acetylcholine receptor. Second, we expect to learn about the mechanism of the thioredoxin reductase from Plasmodium falcipar | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MAYO CLINIC | $182,831 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent proposal Mechanisms of aggregation in light chain Amyloidosis is to dissect the molecular mechanisms that cause light chain amyloidosis (AL) deposits to form. AL is a devastating disease caused by the abnormal proliferation of plasm | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | $54,574 | Grant | Trans-NIH Recovery Act Research Support: Type IV pill (Tfp) are important determinants of bacterial virulence and biofilm formation which is the cause of many opportunistic and chronic bacterial infections. Tfp also mediate a form of bacterial surface motility known as social (S) gliding in Myxo | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $388,306 | Grant | Trans-NIH Recovery Act Research Support: With this administrative supplement we will create one full time research position and to maintain a full time research staff position within our research at Northwestern Univerisity both positions will have full benefits. With the relocation to Northwest | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MIAMI | $208,589 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the parent and proposed research is to investigate the biogenesis of mitochondrial cytochrome c oxidase (COX) in wild type cells and in cells with mutations in evolutionary conserved COX assembly factors. COX deficiency is the most f | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $164,429 | Grant | Trans-NIH Recovery Act Research Support: This ARRA award is an administrative supplement to the parent grant NIH R01GM072080-03 to provide bridge support for the parent project that is in No Cost Extension. The ARRA supplement is to achieve the research goal of applying methods developed in the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | $192,685 | Grant | Trans-NIH Recovery Act Research Support: All cells surround themselves with an extracellular matrix that provides both physical support and protection for the cell. In multicellular organisms the extracellular matrices from individual cells combine to form much larger structures that provide the | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| NORTHWESTERN UNIVERSITY | $128,958 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement will greatly increase the value of the originally proposed project by enabling us to determine the effects of potential regulators on both the tail-microtubule interaction and on tail-mediated regulation of the heads. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CHICAGO, THE | $287,615 | Grant | Trans-NIH Recovery Act Research Support: We are developing our Chaperone-Assisted Crystallography (CAC) technology to solve the structure of protein systems of critical biomedical importance that have been recalcitrant to crystallization by traditional methods. A key innovation is our ability to | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND | $183,024 | Grant | Trans-NIH Recovery Act Research Support: The integrity of the genetic information encoded by DNA is essential to all organisms, yet the reactive bases of DNA are continuously subjected to chemical modification from endogenous and exogenous sources. To counteract this inevitable damage, the cellu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $80,440 | Grant | Trans-NIH Recovery Act Research Support: An Interdisciplinary Approach to PKD2 Function:The long-term goal of this application is to achieve a better understanding of the normal cellular function of TRPP channels. TRPP proteins are a family of calcium permeant channels that are evolutionarily co | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $127,663 | Grant | Trans-NIH Recovery Act Research Support: The experiments in this proposal focus on the optimization and adaptation of the yeast SPP system for expression and isolation of properly folded eukaryotic proteins and membrane proteins for structural, functional and therapeutic applications. The propos | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $111,375 | Grant | Trans-NIH Recovery Act Research Support: The goal of the work described in this proposal is to construct a quantitative and clinically useful assay to measure activity of multiple tyrosine kinases from cellular extracts of chronic myelogenous leukemia (CML) and acute myelogenous leukemia (AML) p | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $120,518 | Grant | Trans-NIH Recovery Act Research Support: This award is funded under the American Recovery and Reinvestment Act of 2009. This project will allow exploration and invention of new synthetic methodology based on key observations made in the context of the parent grant. This support will allow us t | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $159,567 | Grant | Trans-NIH Recovery Act Research Support: This award, 3R01GM075310-04S1, is a competitive Supplement to R01 GM075310 ``Group-Theoretic Methods in Protein Structure Determination'', in which the PI (G. Chirikjian) of the main grant is doing work to match theoretical models of protein loo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE VANDERBILT UNIVERSITY | $141,084 | Grant | Trans-NIH Recovery Act Research Support: MicroRNAs miRNAs?? are a recently discovered family of small ??22 nucleotide?? RNAs that function to regulate gene expression at the post?transcriptional level, mostly by inhibition of translation. Target specificity is due to base pairing interactions be | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF FLORIDA | $260,214 | Grant | Trans-NIH Recovery Act Research Support: Mycoplasmosis is usually subtle, but Mycoplasma alligatoris causes acute lethal primary infection of susceptible hosts. The goal of this work is to explain the mechanisms and evolutionary origins of that virulence. A genome survey indicated that M. alliga | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| WASHINGTON STATE UNIVERSITY | $61,808 | Grant | Trans-NIH Recovery Act Research Support: I will use a combination of experimental and theoretical methods to define the conformational changes at the nucleotide site of myosin associated with the interactions with nucleotides and with actin, along with the relationship of these conformational ch | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON UNIVERSITY, THE | $308,959 | Grant | Trans-NIH Recovery Act Research Support: This request for supplementary funds for R01-GM-077231 is to fund a collaboration between the lab of Professor Kathleen Hall at Washington University School of Medicine, St Louis, MO (parent grant) and that of Associate Professor Alan Van Orden at Colorad | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $342,592 | Grant | Trans-NIH Recovery Act Research Support: Mechanisms Underlying Drug-Diet Interactions - Administrative Supplement Milk thistle is a top 10 selling dietary supplement used to self-treat hepatic disorders and for chemoprevention. The two most common commercial preparations are termed ?silymarin? a | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $144,323 | Grant | Trans-NIH Recovery Act Research Support: The major objective of this supplemental application is to identify genes essential for cell viability in the context of Myc overexpression. To this goal, we propose to document genetic synthetic lethal interactions with moderate Myc overexpression. We wi | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF CONNECTICUT | $200,451 | Grant | Trans-NIH Recovery Act Research Support: This proposal focuses on the application of a chemical approach to understanding and controlling the pathways and machinery of cell motility, processes for which small-molecule inhibitors are presently limited, with the goal of discovering new probes and | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $205,056 | Grant | Trans-NIH Recovery Act Research Support: Sense/Antisense Genetic Coding and the Origins of Translation ARRA (The award title is unchanged, I believe) GM078227-04S1 Principal Investigator: Carter, Charles W. Project Title: Sense/Antisense Genetic Coding and the Origins of Translation Institution: | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $453,600 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic mechanisms make gene expression patterns stable by maintaining gene regulatory information through cell divisions. Proteins encoded by the Drosophila Polycomb Group (PcG) genes maintain key patterns of gene expression during development, likely | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| EMORY UNIVERSITY | $247,488 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Structure/function analysis of the Na/bicarbonate cotransporters. Funding Purpose: The electrogenic sodium/bicarbonate transporter NBCe1 plays an essential role in bicarbonate reabsorption in the kidney that regulates systemic pH in the bo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $143,203 | Grant | Trans-NIH Recovery Act Research Support: Cell migration is essential for many aspects of normal embryonic development as well as in wound healing in the adult. Failure of cells to migrate contributes to birth defects and difficulties in wound healing, whereas unregulated cell migration triggers | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $73,189 | Grant | Trans-NIH Recovery Act Research Support: In striated muscle (skeletal fibers or heart myocytes), ryanodine receptors (RyRs) calcium-release channels play a crucial functional role as they mediate the massive calcium mobilization that produces the twitch contraction of muscles and the beating of | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $230,290 | Grant | Trans-NIH Recovery Act Research Support: Postoperative pain remains a significant problem in up to 30% of postoperative patients. Pain due to related types of inflammatory lesions and trauma affects a large number of additional individuals. Understanding the mediators present near incisional w | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $195,435 | Grant | Trans-NIH Recovery Act Research Support: The mesodermal progenitors are an essential group of embryonic cells required for the formation of the vertebrate body during the process of somitogenesis. Using the many advantages of zebrafish, including optical transparency and the ability to analyze | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $57,290 | Grant | Trans-NIH Recovery Act Research Support: In response to RFA Notice # NOT-OD-09-056, an administrative supplement is being requested to accelerate research studies proposed in NIH/NIGMS funded R01 GM081054 titled Norepinephrine Transport Regulation By Phosphorylation. The major goal of the parent | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $100,760 | Grant | Trans-NIH Recovery Act Research Support: Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms and provide the monomeric precursors required for DNA replication and DNA repair. 1,2 The class I RNRs are composed of two subunits: the alpha-n | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| BRANDEIS UNIVERSITY | $91,268 | Grant | Trans-NIH Recovery Act Research Support: The mechanisms by which animals respond to environmental temperature is not fully understood. C. elegans responds to ambient temperature in a complex, experience-dependent manner. The behavior of C. elegans on a thermal gradient is dependent on its prior | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $108,600 | Grant | Trans-NIH Recovery Act Research Support: Embryonic stem (ES) cells , when cultured as small aggregates in suspension, can differentiate into cystic embryoid bodies (EBs) consisting of an outer endoderm layer, an underlying basement membrane (BM) and the epiblast epithelium that encompasses a ce | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF FLORIDA | $253,916 | Grant | Trans-NIH Recovery Act Research Support: The data obtained to date in the parent grant have shown that A. phagocytophilum strains causing clinical disease in dogs and humans are indistinguishable by current methods. Similarly, horse and squirrel strains appear similar. However, strains infectin | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $68,000 | Grant | Trans-NIH Recovery Act Research Support: How cells regulate and execute cytokinesis, the final step in cell division, remains one of the major unsolved questions in basic biology. Our long-term goal is the systematic dissection of temporal and spatial control during cytokinesis. It has been chal | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $354,165 | Grant | Trans-NIH Recovery Act Research Support: This proposal is an application for a competitive revision to grant 5 R01 GM082834-02 Small molecule probes of cytokinesis in response to Notice Number NOT-OD-09-058 NIH Announces the Availability of Recovery Act Funds for Competitive Revision Application | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $273,992 | Grant | Trans-NIH Recovery Act Research Support: About 2% of proteins in the human genome are predicted to be modified by prenylation. These include a broad range of substrates, but prominent among them are many key proteins involved in cell signaling, growth regulation, cell progression and differentia | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $223,416 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision proposes to expand the scopeof work in the project R01GM083272 entitled Mechanical control of cell growth and differentiation that isdirected at understanding cellular mechanosensing. Aim 1 of this revision builds on preliminary | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $134,431 | Grant | Trans-NIH Recovery Act Research Support: We found that genes expressed in embryonic tissues tend to use different poly(A) sites than those expressed in adult tissues. We then carried out a systematic analysis using all available EST, DNA microarray, and Serial Analysis of Gene Expression (SAGE) | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $86,632 | Grant | Trans-NIH Recovery Act Research Support: Much of the recent progress in protein trafficking is due to new technical advances in live cell microscopy. We are requesting an equipment administrative supplement to upgrade an outmoded 1980's era microscope to a state of the art automated fluorescence | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $60,060 | Grant | Trans-NIH Recovery Act Research Support: Sulfur metabolic pathways are essential for the virulence and survival of human pathogens. In microbial cysteine biosynthesis, sulfonucleotide reductases (SRs) catalyze the reduction of 5'-phosphosulfoadenosine (APS) or 3'-phospho-5'phosphosulfoadenosine | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ROCHESTER | $70,754 | Grant | Trans-NIH Recovery Act Research Support: Studies of language learning in normal infants and children. Detailed measures of eye tracking to assess language processing and detailed measures of language input to infants by mothers. | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $64,856 | Grant | Trans-NIH Recovery Act Research Support: Acquiring a language is among the most daunting feats uniformly accomplished by our species. Explorations of the language learning process present the opportunity to address central issues pertaining to human cognition and its development. The proposed re | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $156,072 | Grant | Trans-NIH Recovery Act Research Support: During my current grant period, we showed that sex determination depends on the antagonism between two opposing signaling pathways, FGF9 and WNT4. Genetic background affects the phenotype of both Fgf9 and Wnt4 mutants, indicating that the balance between | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $34,417 | Grant | Trans-NIH Recovery Act Research Support: Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in MECP2, encoding methyl CpG binding protein 2 (MeCP2). RTT is the only autism-spectrum disorder with a known genetic cause and MECP2 mutations or expression defects are o | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $19,931 | Grant | Trans-NIH Recovery Act Research Support: This summer supplement award provided financial support for a graduate student during the summer months of June, July, and August of 2009. The parent grant, HIV Prevalence, Sexual Behavior, and Attitudes toward Circumcision among MSM (HD 057785), examine | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $34,757 | Grant | Trans-NIH Recovery Act Research Support: Through R01HD057841-01, Assessing and Preventing Obesity Among New Immigrants, we are currently funded to study new immigrants in Somerville and similar surrounding commuities in Massachusetts. The central hypothesis is that an appropriately timed interv | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $169,977 | Grant | Trans-NIH Recovery Act Research Support: The supplement provides funding to allow enrollment of more infants in the current NIH funded series of clinical trials of the impact of probiotics and prebiotics on the intestinal microbiota of premature infants. It includes funds for laboratory equipme | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $255,411 | Grant | Trans-NIH Recovery Act Research Support: This proposal is in response to NIH NOT-OD-09-056, ?Recovery Act Funds for Administrative Supplements.? This administrative supplement will support research aims that are within the scope of the currently funded parent grant, ?Interventions in Mathematica | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $117,876 | Grant | Trans-NIH Recovery Act Research Support: Adrenomedullin Signaling At the Maternal-Fetal Interface-ARRA Plasma levels of the angiogenic peptide adrenomedullin (AM) rise dramatically during a normal pregnancy and are often blunted during complications of pregnancy, like preeclampsia. Using genet | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MARYLAND | $71,250 | Grant | Trans-NIH Recovery Act Research Support: We propose to utilize the additional funds provided by this ARRA supplement to extend our efforts to producing assemblies of large genomes from data obtained from the novel short-read sequencing technologies that is currently being produced with technique | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $51,373 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this request for administrative supplements is to allow for Summer Research Experiences for Science Educators, which will accelerate our research project in determining the role and mechanisms of issue kallikrein in cardiac protection after | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $8,200 | Grant | Trans-NIH Recovery Act Research Support: Since the original budget period this application, the PI has offered summer college students an opportunity to work on projects related to the physiological questions proposed in the grant proposal. This gives the students the opportunity to learn labora | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $7,200 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research experience is to provide an undergraduate student an opportunity to gain hands-on knowledge of a clinically significant disease process and a better understanding of how changes at the level of a cell can translate to an alterati | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| J.DAVID GLADSTONE INSTITUTES, THE | $26,243 | Grant | Trans-NIH Recovery Act Research Support: We propose to create a flexible polycistronic system for expressing multiple engineered receptors to facilitate the engineering of tissues, such as cardiac cells, brain, and bone. We developed new class of G-protein- coupled receptors (GPCRs) that are cal | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $22,272 | Grant | Trans-NIH Recovery Act Research Support: To engineer and implant autologously-derived tissue constructs to act as an electrical conduit from the atria to the ventricles of the heart for use in pediatric patients that have complete heart block. Ultimately, our studies are designed to provide a re | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $205,200 | Grant | Trans-NIH Recovery Act Research Support: Mast cells and their products are known participants in the progression of atherosclerosis. Histamine is a major vasoactive amine present in the cytoplasmic granules of mast cells. A direct relationship between histamine and vascular inflammation is evi | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| DUKE UNIVERSITY | $27,453 | Grant | Trans-NIH Recovery Act Research Support: The objective of this proposal is to determine how changes in intracellular Ca2+, the ultimate signal of electrical activity, regulate cardiac membrane excitability. Dysregulation of Ca2+, however, contributes to cardiac arrhythmias. Given the potential p | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF NEVADA, RENO | $135,439 | Grant | Trans-NIH Recovery Act Research Support: Dr. Normand Leblanc, Professor in the Department of Pharmacology at the University of Nevada School of Medicine is the Principal Investigator on an R01 project supported by the NHLBI (5R01 HL075477) entitled ?Properties of ClCa Channels in Vascular Myocyt | Health and Human Services, Department of / National Institutes of Health | 7/01/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $219,888 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Recent studies indicate that platelet activation plays an important role in all stages of atherosclerotic lesion formation: initiation, progression, stability and thrombosis triggered by plaque rupture. Another event t | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $170,374 | Grant | Trans-NIH Recovery Act Research Support: The goal of the supplement is to increase and extend our progress on the specific aims described in HL 078726. Specifically, additional labor is needed to speed the animal work examining the in vivo atherosclerotic properties of Platelet Factor 4 (PF4) d | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $291,465 | Grant | Trans-NIH Recovery Act Research Support: Surgical vein bypass grafts fail principally due to development of neointimal hyperplasia, especially in the setting of low flow within the conduit. Inflammation stands as a pathologic feature of this process. While cytokines have been implicated in vein | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $263,810 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent grant (R01 HL79235) is to understand how depression leads to heart failure (HF) in older adults. Depression is an important risk factor for the development of HF and for adverse outcomes in patients with existing HF. However, the me | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $291,756 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request under ARRA is to support additional research assistants for the REasons for Geographic And Racial Differences in Stroke-Myocardial Infarction Study, R01HL080477. The R01 will end April 30, 2011, and is thus eligible | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $223,568 | Grant | Trans-NIH Recovery Act Research Support: Chronic inflammation is a debilitating and potentially life threatening condition that occurs in a number of diseases. Cells of the blood vessel walls control chronic inflammation by allowing the recruitment the immune cells from the blood into tissues. T | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MAYO CLINIC | $241,867 | Grant | Trans-NIH Recovery Act Research Support: This Recovery Act Administrative Supplement request to R01 HL-81753 is designed to support a postdoctoral fellow, Dr. Yonghe Ding, and accelerate the collection of data associated with the parent award. Dr. Ding will replace Mr. Ruilin Zhang, a graduate s | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $324,161 | Grant | Trans-NIH Recovery Act Research Support: We have recently demonstrated that Related Transcription Enhance Factor-1 (RTEF-1) is a transcription factor in endothelial cells. We have also determined that angiogenic factors such as Vascular Endothelial Growth Factor (VEGF) is a transcriptional targe | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $291,116 | Grant | Trans-NIH Recovery Act Research Support: Atrial fibrillation (AF) is the most common heart rhythm disorder, affecting 2.2 million individuals in the United States alone, and is a major cause of morbidity and mortality. Current methods to eliminate AF with anti-arrhythmic drugs and ablation remai | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $261,772 | Grant | Trans-NIH Recovery Act Research Support: HIV infected persons have an increased incidence of emphysema compared to those without HIV infection, and it has been hypothesized that this accelerated disease progression is the result of one or more latent infectious agents that amplify the fulmonary | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $332,423 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement has supported the development of the MADCaP consortium, an international multicenter group of prostate cancer studies. This project is highly efficient and will be able to respond quickly to the important question of geneti | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $347,600 | Grant | Trans-NIH Recovery Act Research Support: The best-understood function of the Kip family of cdk inhibitors is to inhibit cdk2 and induce cell cycle exit. Our laboratory also showed that p21 also has roles in differentiation, proliferation and tumor development. Furthermore, p21 accumulation is as | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| THE VANDERBILT UNIVERSITY | $4,721,145 | Grant | Trans-NIH Recovery Act Research Support: Supplemental funds are requested to enable the collection of additional information and biospecimens to enhance the Southern Community Cohort Study (SCCS) as a unique national resource for investigating cancer disparities. Nearly 90,000 adults age 40-79, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $275,116 | Grant | Trans-NIH Recovery Act Research Support: NOT-OD-09-056 NIH Announces the Availability of Recovery Act Funds for Administrative Supplements: Creating the Encyclopedia of DNA Elements (ENCODE) in the Human Genome U54 The primary focus of our ENCODE group is to generate an open chromatin atlas tha | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $203,723 | Grant | Trans-NIH Recovery Act Research Support: This project will study the optimization of speeded decisions, and the control and monitoring mechanisms that serve this optimization by balancing performance costs and benefits. These lines of work will be pursued under two specific aims. First, we will | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $207,456 | Grant | Trans-NIH Recovery Act Research Support: Prospective Studies of the Pathogenesis of Schizophrenia - ARRA- We will determine whether the repellent axon guidance cues ephrinA5 and ephrinB1 disrupt inhibitory synaptic development and maturation or pruning of interneuron arbors in novel ex vivo orga | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| UNIVERSITY OF PITTSBURGH THE | $181,049 | Grant | Trans-NIH Recovery Act Research Support: Parkinsons disease (PD) poses a serious threat to the health of a large segment of our society. The present project focuses on strategies for inducing endogenous neuroprotective mechanisms in animal models of the dopamine (DA) deficiency associated with P | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $616,130 | Grant | Trans-NIH Recovery Act Research Support: Generalized vitiligo is the most common pigmentation disorder, autoimmune death of melanocytes resulting in white patches of skin and hair, and patients are at high risk of other autoimmune diseases such as thyroid disease, adult type 1 diabetes, rheumato | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $56,550 | Grant | Trans-NIH Recovery Act Research Support: This grant provides a summer research experience for three undergraduate students in health-related scientific research. The goal of the overall project is elucidation of the program of gene expression regulated by PI 3-kinase/Akt/GSK-3 signaling, which i | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF CHICAGO, THE | $90,240 | Grant | Trans-NIH Recovery Act Research Support: The broad goal of the proposal is to understand the functional organization of the early thalamocortical stages of processing in the auditory system. This involves a better functional understanding of the various pathways connecting the inferior colliculu | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $180,175 | Grant | Trans-NIH Recovery Act Research Support: One of the few accepted treatments for severe non-fluent aphasia is Melodic Intonation Therapy (MIT). Inspired by the common clinical observation that patients can actually sing the lyrics of a song better than they can speak the same words, MIT emphasize | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $319,593 | Grant | Trans-NIH Recovery Act Research Support: The supplement proposes highly translational activities that will implement unique signal processing algorithms learned from the parent grant in an advanced hearing aid platform. The unique features include pitch enhancement, frequency transposition and | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF WASHINGTON | $147,522 | Grant | Trans-NIH Recovery Act Research Support: Obstructive sleep apnea occurs in 2-4% of middle age adults and results in significant morbidity and mortality. The first line therapy is provision of continuous positive airway pressure (CPAP) via a nasal mask chronically. Nasal resistance related to nas | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| EAST TENNESSEE STATE UNIVERSITY | $205,920 | Grant | Trans-NIH Recovery Act Research Support: The mechanisms that allow cells to sense and respond to [O2] are of fundamental importance in understanding a number of pathological processes. Recently the cellular [O2]-sensing mechanism has been identified as a family of [O2]-dependent prolyl hydroxyla | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| THE JACKSON LABORATORY | $1,003,508 | Grant | Trans-NIH Recovery Act Research Support: Many common inherited human diseases - such as diabetes, cardiovascular disease, obesity, and cancer - are genetically complex; that is, they result from the interaction of more than one gene. Additionally, research has shown that susceptibility or resist | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $250,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to allow BMRB to address the needs of its user community and to make the archive fully accessible to the scientific community through the internet. BMRB users are demanding more comprehensive tools for querying and retriev | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| GENETIC INFORMATION RESEARCH INSTITUTE | $250,000 | Grant | Trans-NIH Recovery Act Research Support: This funding was devoted to the accelerated development of Repbase, an internationally recognized database of repetitive DNA. It helped us to significantly increase our computer power, and we could retain one highly trained Ph.D. scientist on this project | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $163,453 | Grant | Trans-NIH Recovery Act Research Support: Title: Biophotonics Summer Undergraduate Research Program (BSURP). This administrative supplement to the Laser Microbeam and Medical Program (LAMMP P41RR01192) supports a two year Biophotonics Summer Undergraduate Research Program (B-SURP) for the summers | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | $1,944,069 | Grant | Trans-NIH Recovery Act Research Support: Carbohydrate structures attached to glycoproteins, glycolipids, and proteoglycans play numerous roles in biological recognition events in animal systems. A full understanding of the biochemistry of mammalian glycosylation enzymes, including their use in c | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| HUGO W. MOSER RESEARCH INSTITUTE AT KENNEDY KRIEGER, INC. | $894,666 | Grant | Trans-NIH Recovery Act Research Support: This is a proposal to extend our image analysis technologies developed in the parent grant to translational researches. In the parent grant, we developed cutting-edge atlas-based automated brain segmentation and user-interface software for dissemination. | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $888,977 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to disseminate the Appion Processing Pipeline to the scientific research community. Appion is a software infrastructure that enables and streamlines the complex set of tasks that are required for reconstructing a 3D density map | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $97,304 | Grant | Trans-NIH Recovery Act Research Support: The goal of this ARRA funding request was to identify a deserving and promising minority Graduate Student Researcher (GSR) and provide this GSR with mentoring and the opportunity to develop scientific research skills. The overall goal of the parent grant | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| WISTAR INSTITUTE OF ANATOMY & BIOLOGY (INC) | $175,825 | Grant | Trans-NIH Recovery Act Research Support: The intent of the Wistar/Penn SPORE in Skin Cancer is to decrease the morbidity and mortality of skin cancers through improved understanding of the pathogenesis of these diseases using novel, validated molecular biomarkers of risk, progression and prognos | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| WASHINGTON UNIVERSITY, THE | $1,592,888 | Grant | Trans-NIH Recovery Act Research Support: This supplement funds two projects under the parent grant. The first project will accelerate progress in meeting the research aims of Ozioma in CECCR-II by creating a fully automated online system OziomaOnline to customize cancer news, data, and resour | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $301,352 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent Center for Childhood Asthma in the Urban Environment (CCAUE) grant (5P50ES015903) RFA is to increase understanding of the ways exposure to indoor and outdoor airborne particulate matter and allergens result in airway inflammation an | Health and Human Services, Department of / National Institutes of Health | 9/19/2009 |
| UNIVERSITY OF UTAH, THE | $467,025 | Grant | Trans-NIH Recovery Act Research Support: Our Center for the Structural Biology of Cellular Host Elements in Egress, Trafficking, and Assembly of HIV CHEETAH studies the structural biology of HIV/Host interactions involved in viral trafficking and assembly. Here, we request funds that will enabl | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $46,350 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This proposal seeks to improve care for the women who suffer the priority health conditions of pelvic floor dysfunction; problems that arise due to women's unique role in giving birth. It addresses the sex disparities | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $600,000 | Grant | Trans-NIH Recovery Act Research Support: Under the support of the parent grant, the development of each experimental tool has advanced to the point that they have been validated. This supplement requests support for the final steps in refining these technologies, through the support of three ke | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $176,830 | Grant | Trans-NIH Recovery Act Research Support: The MGH/MIT Morris Udall Center of Excellence in PD Research is taking a broad, collaborative and interactive approach to the study of Parkinson's disease. The Projects address critical questions concerning the selective vulnerability of dopamine neurons, | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $8,528 | Grant | Trans-NIH Recovery Act Research Support: ARRA Summer Research Experience: StudentParent Project-50NS038377, The Morris K Udall Parkinson's Disease Research Center for Excellence, Project 3: LRRK2 Biology in PD. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $107,444 | Grant | Trans-NIH Recovery Act Research Support: The goal of this ARRA application is to accelerate the pace of the current scope of the PENN Udall Center while adding retaining jobs. Briefly, the goals of this Udall Center are to elucidate mechanisms of brain degeneration in patients with Parkinson s d | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $280,416 | Grant | Trans-NIH Recovery Act Research Support: Nonhuman primate (NHP) models are essential tot the conduct of translational research and the advancement of biomedical science. Because of their close phylogenetic relationships, nonhuman primates are the closest physiological, genetic, and anatomical mo | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $328,081 | Grant | Trans-NIH Recovery Act Research Support: A. Specific Aims Despite extensive knowledge of the basic blueprint of cortical circuits, detailed knowledge about local cortical circuits, the connectivity of specific cell types and how they function is still limited. The studies originally proposed in | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $80,484 | Grant | Trans-NIH Recovery Act Research Support: The mechanism underlying G protein-coupled receptor (GPCR)-mediated signaling systems is still unresolved despite the intense focus these systems have received over the past century. This is due in part to the difficulties in studying membrane proteins in | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $232,184 | Grant | Trans-NIH Recovery Act Research Support: The long-term goals of our laboratory remain as they have been for over 15 years: to gain an increased understanding of the pathogenic mechanisms operative in otitis media (OM), with a focus on disease caused by nontypeable Haemophilus influenzae (NTHI). | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $112,437 | Grant | Trans-NIH Recovery Act Research Support: This grant provided summer research experiences for three high school students and three college students. The purpose of this award is to educate the students in an area of research that they may not otherwise be exposed to, specifically, alcohol epidemi | Health and Human Services, Department of / National Institutes of Health | 6/09/2009 |
| WASHINGTON UNIVERSITY, THE | $202,231 | Grant | Trans-NIH Recovery Act Research Support: The supplemental request under NOT-OD-09-056 supports the science of the parent project AA12640 Alcoholism: epidemiologic high risk family study and the aims of the Recovery Act through its dual objectives. The first is to retain project staff to enable | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $37,414 | Grant | Trans-NIH Recovery Act Research Support: Continuation of R01 Grant AA013745. The initial grant was to investigate the role of alcohol-induced intestinal permeability in alcholic liver disease (ALD). Goal of continuation; Aim 1: Complete statistical analysis of patient demographic and contrib | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $154,000 | Grant | Trans-NIH Recovery Act Research Support: This proposal is the third submission of application number R01 AA013806-01 which was originally submitted in response to Request for Application Number AA02.002 (Research on Alcohol Health Disparities) and most recently reviewed February 13, 2003 by the | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| SOUTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION | $35,852 | Grant | Trans-NIH Recovery Act Research Support: This study is aimed at directly addressing the possible involvement of survivin in protection to the stomach against alcohol-induced damage and in promoting healing of alcohol-induced injury. We also wish to assess whether survivin is involved or require | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| GEORGETOWN UNIVERSITY (THE) | $12,894 | Grant | Trans-NIH Recovery Act Research Support: Once women enter menopause, they lose their protection from hypertension, cardiovascular disease and progressive renal disease when compared to age-matched premenopausal women and age-matched men. In the first funding period, we found that experimentally | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| SOUTHERN ILLINOIS UNIVERSITY | $60,952 | Grant | Trans-NIH Recovery Act Research Support: Project Title: Interaction of caloric restriction with longevity genes Calorie restriction (CR) and longevity genes related to growth hormone signaling prevent age-related disease, extend healthspan and increase life expectancy. Studies of mice in our la | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $205,096 | Grant | Trans-NIH Recovery Act Research Support: In a parent grant entitled Quantitative Analysis of Cerebral Cortex in Aging Monkeys (R01AG021133-4) we have proposed to study alterations in microcolumns throughout the entire cerebral cortex of monkeys of both sexes and ages that cover the entire adult | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS AT DALLAS | $290,712 | Grant | Trans-NIH Recovery Act Research Support: There is a considerable amount of social and behavioral data that is correlational in nature suggesting that individuals who are deeply engaged in social and intellectual activities in mid and late adulthood show delays in normal age-related cognitive dec | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $119,903 | Grant | Trans-NIH Recovery Act Research Support: This supplement to our parent grant G?Racial Discrimination and Risk of Chronic DiseaseG? (5R01AG027122-03), has two specific aims: --Aim 1: Hire an additional research assistant (RA) to assist with recruiting and obtaining the survey, anthropometric, and | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $186,330 | Grant | Trans-NIH Recovery Act Research Support: Combining brain imaging with learning measures and high-density EEG recordings of human sleep, this award will determine the impact of age-associated sleep loss, and recovery, on the ability to form new human memories. We aim to examine the relationship | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $152,880 | Grant | Trans-NIH Recovery Act Research Support: This opportunity for supplmental funding is timely and scientifically needed given new technologies and rat-specific molecular tools which can accelerate Parent grant Aims 1 and 2 significantly over the next two years. With additional personnel and acquis | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF FLORIDA | $712,744 | Grant | Trans-NIH Recovery Act Research Support: In our currently funded project (R01 AG033906), we propose to: 1) characterize ethnic differences in experimental pain sensitivity, endogenous pain inhibition, clinical pain and pain-related disability among older African Americans and non-Hispanic whites | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF CHICAGO, THE | $120,000 | Grant | Trans-NIH Recovery Act Research Support: The longitudinal study of the CHASRS sample began in 2002 with a population-based sample of 229 adults 50 to 67 years old. We have been accumulating broad and richly deep data to optimally address how psychosocial factors, especially objective and perceiv | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $450,856 | Grant | Trans-NIH Recovery Act Research Support: During the last funding interval as a merit award, this grant focused on the T cell receptor (TCR) complex composed of an heterodimer and non-covalently associated CD3 signaling components. We continued crystallographic analysis with TCRs, providing the | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $52,396 | Grant | Trans-NIH Recovery Act Research Support: Purchase of three items of equipment necessary to studies pertaining to the mechanism of action of PspA and related pneumococcal virulence proteins currently funded by NIH project AI21548. The equipment will not only enhance our ability to reach the goal | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $377,770 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement was to bring a very experienced scientist, Dr. Jihong Dai, back to our laboratory to conduct studies related to our parent grant. Dr. Dai was formerly a post-doctoral fellow in the laboratory and returned to t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $171,651 | Grant | Trans-NIH Recovery Act Research Support: The research supplement will be used to support the training of a Latino/Hispanic American (Mexican Descent) postdoctoral scholar who is currently working in an Infectious Diseases Laboratory at School of Public Health, University of California at Berkele | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| WASHINGTON UNIVERSITY, THE | $184,340 | Grant | Trans-NIH Recovery Act Research Support: We are currently conducting what we believe is the first large-scale study to address the effectiveness of auditory training longitudinally, to compare training methods, and to identify patient variables that predict benefit. The purpose of this applicati | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ROCHESTER | $144,284 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of our research program is to understand the functional role(s) of the vestibular efferent system. The current objective is to close the gap between the synaptic actions of vestibular efferent stimulation and the functional, physiolog | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |