Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| UNIVERSITY OF WISCONSIN SYSTEM | $177,086 | Grant | Trans-NIH Recovery Act Research Support: : This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provide | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| HOUSE EAR INSTITUTE INC | $190,759 | Grant | Trans-NIH Recovery Act Research Support: We propose to dramatically revise our research software to fully implement internet capability, improve G?user-friendliness,G? expand the training modules, and address known issues with the current software. Ultimately, we intend to develop a release of t | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HOUSE EAR INSTITUTE INC | $172,481 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an administrative supplement in response to NOT-OD-09-056, title: Accelerating the Science, title code: ACC to the NIDCD. In this supplement, we aim to accelerate the parent grant through: 1) recruiting technical staff that cond | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| FATHER FLANAGAN'S BOY'S HOME INC | $197,642 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to fund two part-time undergraduate research assistants and purchase supplies to conduct studies of neuronal circuitry in the octopus region of the PVCN. Making brain sections and learning the method of inserting dyes into | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $198,093 | Grant | Trans-NIH Recovery Act Research Support: Our senses of hearing and balance depend on the intricate three-dimensional structure of the inner ear. The inner ear has a coiled cochlea for hearing as well as three hollow canals oriented with the three dimensions of space, a system that is used for d | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $142,942 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to add technical staff that will accelerate the pace of research outlined in the parent R01 'Sequencing and Initiation in Speech Production.' The primary aim of the parent grant is to develop and experimentally test a neu | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $480,900 | Grant | Trans-NIH Recovery Act Research Support: We are currently in the second year of a five-year R01 grant (DC007695), titled 'Development of the Calyx of Held'. In this competing revision, we propose to extend the scope of and implement new technologies for our investigation of neural circuit forma | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $145,994 | Grant | Trans-NIH Recovery Act Research Support: Proper perception and behavioral response to the environment by humans is essential for our health and well-being. Our understanding of sensory physiology and sensory-driven behavior has greatly benefited from the surprising conservation of mechanisms bet | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF IOWA, THE | $128,861 | Grant | Trans-NIH Recovery Act Research Support: Speech perception is a process of mapping continuous detail in the acoustic signal onto discrete units of meaning like words. Given the variability in the signal and speed at which it arrives, the system must cope with a great deal of variation in a small | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MARINE BIOLOGICAL LABORATORY, THE | $278,811 | Grant | Trans-NIH Recovery Act Research Support: The ARRA Administrative Supplemental award proposed to hire new staff to accelerate both the morphological and physiological components of the prime award, that of studying the mechanism(s) of synaptic transmission between the type I hair cell and its sur | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $164,960 | Grant | Trans-NIH Recovery Act Research Support: Title: ?Neural Networks for Speech Perception in Noise? Thirty million Americans with hearing loss struggle daily to understand speech in noisy environments. A neuroscientific understanding of this problem could improve diagnosis and treatment, and wil | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MASSACHUSETTS EYE AND EAR INFIRMARY & PHYSICIAN STAFF, INC. | $84,133 | Grant | Trans-NIH Recovery Act Research Support: Vestibular Prosthesis Tested in a Vestibulopathic Model Under this supplement application we propose to purchase and use new equipment to control the motion devices used to assay prosthesis effectiveness. | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| UNIVERSITY OF ARIZONA | $206,981 | Grant | Trans-NIH Recovery Act Research Support: This proposal requested funding for two pieces of equipment, a cryostat and an RT-PCR system. The cryostat is necessary in our exploration of the molecular bases of developmental interactions between axons and glial cells that are critical for the precis | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| FATHER FLANAGAN'S BOY'S HOME INC | $219,340 | Grant | Trans-NIH Recovery Act Research Support: This supplement will validate a novel method developed by us to quantify the matrix potential to calcify. This method uses a Fura-2 calibration kit to G?extractG? Ca2+ from matrix proteins to better test the hypothesis that Oc90 can lead to accumulation o | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| ROCHESTER GENERAL HOSPITAL | $68,800 | Grant | Trans-NIH Recovery Act Research Support: NTHI Immunity in Young Children (Summer supplement): The parent grant seeks to understand the pathogenesis of Nontypable Haemophilus influenzae (NTHi), one of the major etiological agents of acute otitis media (AOM), which has very high morbidity among c | Health and Human Services, Department of / National Institutes of Health | 6/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $247,491 | Grant | Trans-NIH Recovery Act Research Support: Effect of cytokines in chronic rhinosinsusitis on olfactory neuron function: The purpose of the parent grant is to study the mechanism of olfactory loss in patients with chronic rhinosinusitis (CRS). The loss of the sense of smell is a common symptom of C | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CONNECTICUT | $600,880 | Grant | Trans-NIH Recovery Act Research Support: This application is in response to Notice Number NOT-OD-09-058, Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. The parent project investigates the development of bimodal bilingualism by studying | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $249,109 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to support students who will work on determining the physiological properties of the olfactory sensory neurons and to determine aberrant axonal targets in CNGA2 and TRPM5 knockout mice. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $169,894 | Grant | Trans-NIH Recovery Act Research Support: One cognitive function often taken for granted is the ability to maintain a sense of direction and location while moving about in the environment. This awareness is essential for getting around and functioning normally in the world. When our sense of spat | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $52,625 | Grant | Trans-NIH Recovery Act Research Support: We received funds to enable hiring of a University of California (UCSD) and a Harvard undergraduate student (both US citizens) for full time summer research experience. One student has been working part time in my lab, unpaid, for course credit during th | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| HUNTINGTON MEDICAL RESEARCH INSTITUTES | $203,431 | Grant | Trans-NIH Recovery Act Research Support: Manufacture multisite silicon substrate neural probes fabricated by Bosch process deep reactive ion etching. The probes will be used to help wiith reserarch of a neural prosthesis device to restore function of the cochlear nucleus nerve in the ear. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF LOUISVILLE | $520,413 | Grant | Trans-NIH Recovery Act Research Support: We have recently identified a novel protein secretion pathway (proposed to be a Type IX Secretion System; T9SS) employed by periodontopathogens, including Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia to secrete a number of v | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| DUKE UNIVERSITY | $10,920 | Grant | Trans-NIH Recovery Act Research Support: Sensory representations within the thalamocortical loop (TCL) are dynamically modulated constructs that emerge from the asynchronous convergence of multiple ascending and descending afferents. Also, tactile neuronal responses in S1 layers differ profoundl | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| OMNITEC SOLUTIONS, INC. | $367,146 | Contract | : PRINCIPAL ENGINEER/ANALYST TO LEAD EFFORT TO DEFINE NDAR DATA DICTIONARY; TRAIN INVESTIGATORS TAKING OVER THIS FUNCTION; HELP TO STANDARDIZE PROCESS/PROCEDURE FOR QA/QC OF EXPECTED RAPID INCREASE THROUGH ARRA OF DATA COMING INTO NDAR. | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $508,512 | Grant | Trans-NIH Recovery Act Research Support: Function and Form Outcomes in Infant Cleft Lip Surgery-ARRA This application is in response to NOT-OD-09-058, titled ?NIH announces the availability of Recovery Act Funds for Competitive Revision Applications?. The goal of this application, which is rel | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF PITTSBURGH THE | $305,278 | Grant | Trans-NIH Recovery Act Research Support: This grant is an ARRA administrative supplement to 2-R01-DE016148 (Extending the Phenotype of Nonsyndromic Orofacial Clefts). This supplement adds a new collaboration that will add facial movement studies to the project. Through this new collaboration | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| FORSYTH DENTAL INFIRMARY FOR CHILDREN | $127,285 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplemental application is to accelerate the pace and achievement of the goals set forth in the parent grant entitled, Matrix Protein Regulation of Enamel Mineral Formation through 1) the establishment of a new collaboration and 2) by | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $132,416 | Grant | Trans-NIH Recovery Act Research Support: The scope of the original application was to characterize the hemin/iron uptake mechanisms in Porphyromonas gingivalis with an emphasis on the examination of the regulation mechanisms as well as the analysis of the components of the hmu operon. In this re | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $374,067 | Grant | Trans-NIH Recovery Act Research Support: The goal for the parent R01 was to investigate the effect of antiretroviral therapy (ART) on the life cycle of oral HPV infections in different types oral epithelium. Our hypothesis was that ART affects the host tissue and/or the natural history of HPV, i | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $0 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is to purchase a dissecting microscope with imaging functionality. This instrument will be used to obtain consistent high quality preparations to be used in Specific Aim 2 of the parent proposal. The microscope will also be | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TEXAS A&M UNIVERSITY SYSTEM,THE | $362,874 | Grant | Trans-NIH Recovery Act Research Support: The development of dentition involves a complex series of epithelial-mesenchymal signaling interactions. It is not surprising that such a process is prone to disturbances which then manifest as congenital tooth agenesis in up to 10% of the population and | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO | $106,033 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will satisfy the requirements of the program in that the additional personnel and scientific activities performed accelerates the tempo of scientific research in achieving specific aims and advance the objective of the Recov | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $16,687 | Grant | Trans-NIH Recovery Act Research Support: Summer experience for high school science teacher and undergraduate student considering career in research. Worked on studies funded by primary grant. They participated in whole animal research, didactic lectures related to scientific method, project fo | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $98,944 | Grant | Trans-NIH Recovery Act Research Support: Amerindians in Chile likely migrated from Asia thousands of years ago, and East Asian strains of H. pylori produce a more pathogenic CagA motif than European strains. A substantial portion of Amerindians live in isolated, relatively less hygienic rural c | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $73,718 | Grant | Trans-NIH Recovery Act Research Support: The molecular basis for the gene specific effects of butyrate remains poorly defined. Butyrate's major known function involves inhibition of histone deacetylases (HDACs) resulting in increased acetylation. In addition to histone acetylation, it is now kno | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF KENTUCKY | $32,332 | Grant | Trans-NIH Recovery Act Research Support: Normal regulation of insulin gene transcription by glucose is essential for the maintenance of glucose homeostasis, and requires the beta-cell specific transcription factors Pdx-1, MafA and NeuroD1. However the exact mechanism(s) by which glucose increase | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $46,738 | Grant | Trans-NIH Recovery Act Research Support: The IGF-I (Insulin-like Growth Factor) receptor (IGF-IR) activates pathways associated with tumorigenesis including hyperproliferation, survival and invasion. Studies outlined in the parent grant aimed to identify and characterize novel genes critically i | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $54,000 | Grant | Trans-NIH Recovery Act Research Support: Helicobacter pylori is a highly adaptive pathogen that escapes host bacterial defenses (i.e., gastric acid and humoral immunity) leading to chronic infection. The broad, long-term objective of this proposal is to elucidate the factors contributing to the | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $50,760 | Grant | Trans-NIH Recovery Act Research Support: Liver disease is a common cause for morbidity and mortality in the U.S., and understanding the critical pathways during liver development is essential for our knowledge of normal liver function and disease. The zebrafish is an excellent model to study ear | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $109,877 | Grant | Trans-NIH Recovery Act Research Support: Mutations in rhodopsin are the most common causes of hereditary forms of Retinitis Pigmentosa (RP). Many of these mutations lead to misfolding of rhodopsin protein and retention within the endoplasmic reticulum (ER). The molecular pathways that link rhodo | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $50,000 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Thyroid-related eye disease (TED) is an important public health burden that causes loss of productivity and reduces quality of life. TED can lead to chronic debilitating pain and headaches, double vision, corneal expos | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| THE VANDERBILT UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplement is to extend findings and hypotheses from the parent grant which proposed that functional variants in drug efflux transporter genes (MRP2, BSEP and BCRP) contribute to wide interpatient variability in chemotherapy disposition. | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Sepsis is a disease process characterized by a systemic inflammatory response to an underlying infection. In the United States, 750,000 people develop severe sepsis annually and despite recent advances in critical care, over 210,000 people die each year. | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| DUKE UNIVERSITY | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Described below is an administrative supplemental request for an actively funded K08 grant entitled Non Muscle Myosin II Contractility Putatively Regulates Scar Contracture. This proposal has been devised based on the goals of the NIGMS-Specific Requireme | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $105,372 | Grant | Trans-NIH Recovery Act Research Support: The proposed interdisciplinary study allows the candidateto further develop his knowledge of MR physics and expertise in imaging studies of adrenomyeloneuropathy(AMN), a form of adrenoleukodystrophy(AID), while providing rigorous exposureto the clinical a | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| EMORY UNIVERSITY | $301,075 | Grant | Trans-NIH Recovery Act Research Support: INSTITUTIONAL RESEARCH AND ACADEMIC CAREER DEVELOPMENT The Fellowships in Research and Science Teaching (FIRST) program is a consortium of two research- intensive institutions, Emory University and the Morehouse School of Medicine (MSM), and the three mi | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $228,498 | Grant | Trans-NIH Recovery Act Research Support: This supplement is made under the Research Supplement to Promote Re-Entry into Biomedical and Behavioral Research Careers program. The project is designed to provide the mentored individual training and a strong background in current molecular and genomic | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $344,260 | Grant | Trans-NIH Recovery Act Research Support: In this project we seek to pursue as a new and additional specific aim the development of practical synthetic routes to the cortistatin family of alkaloids, broadly defined. Our approach is based on a versatile advanced synthetic template from which a div | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $136,311 | Grant | Trans-NIH Recovery Act Research Support: We have advanced the development of an imaging method for CRAds based upon capsid incorporation of imaging motifs. This capacity allowed assessments of CRAd parameters in vivo related to viral persistence. On the basis of these findings, we sought to exp | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| LOYOLA UNIVERSITY | $83,388 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to provide a student with post-master's training. The minority fellowship plan will provide her with a 2-year translational research experience within the aims and scope of the parent R01 project. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | $290,193 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this research project is to improve the accuracy and reliability of cone-beam computed tomography (CBCT) guidance of radiation treatment in lung and liver. The treatment of inoperable tumors in lung and liver remains a therapeutic chal | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $613,740 | Grant | Trans-NIH Recovery Act Research Support: Quitting smoking adds an average of seven years to a parent's life, improves the health of the spouse, eliminates the majority of secondhand smoke (SHS) exposure of the children, reduces tobacco-related poor pregnancy outcomes, eliminates the greatest cau | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $310,860 | Grant | Trans-NIH Recovery Act Research Support: 15-PGDH is a prostaglandin degrading enzyme that my laboratory, in a recent from the cover PNAS paper, has shown is a new candidate colon cancer suppressor gene that acts as an enzymatic antagonist of the COX-2 prostaglandin synthesizing colon cancer onco | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER | $368,000 | Grant | Trans-NIH Recovery Act Research Support: The long term objective of this proposal is to gain insight into the mechanisms involved in Toll-like receptor (TLR) enhancement of anti-tumor immune therapy and to translate these findings towards practical immunotherapies for patients with metastatic tu | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| MAYO CLINIC | $269,744 | Grant | Trans-NIH Recovery Act Research Support: Increased mammographic breast density is one of the strongest risk factors for breast cancer, is common in the population, and may account for a large proportion of cases of breast cancer. This supplement enhances the overall goal of R01 CA128931 to ident | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $227,316 | Grant | Trans-NIH Recovery Act Research Support: Lung cancer is the leading cause of cancer-related deaths, with the majority of deaths due to failed therapy from tumor drug resistance. As described in the original application, we have developed a microarray screen for identifying differentially express | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| CANCER PREVENTION INSTITUTE OF CALIFORNIA | $255,467 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to conduct a pilot study to assess Vietnamese American social networks and their roles in CRC screening to accelerate the tempo of scientific research. The specific aims are: 1) To qualitatively identify a | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $99,900 | Grant | Trans-NIH Recovery Act Research Support: In our parent grant, we propose a unique academic-industrial partnership between investigators at the University of California San Diego (Academic Partner) and AntiCancer, Inc. (Industrial Partner) to develop and validate color-coded fluorescent imaging s | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $238,605 | Grant | Trans-NIH Recovery Act Research Support: Cardiac remodeling is triggered in response to mechanical stress and various neurohumoral factors. We have recently discovered that protein kinase D (PKD), which has been scarcely studied in cardiomyocytes, plays a significant role to regulate cardiac hyp | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| DUKE UNIVERSITY | $117,744 | Grant | Trans-NIH Recovery Act Research Support: The injured human heart has an extremely limited ability to repair itself through regeneration of cardiomyocytes.By contrast with mammals, we found a few years ago that the teleost zebrafish displays a highly efficient regenerative response to cardiac inj | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $246,322 | Grant | Trans-NIH Recovery Act Research Support: The goal of this administrative supplement is to provide resources to extend the studies outlined in our parent grant R01 on the identification and the biology of miRNAs in the developing lung. A large number of studies now support a major role of miRNA-m | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $237,970 | Grant | Trans-NIH Recovery Act Research Support: Oxidative modification of LDL is an important, if not obligatory, step that mediates the atherogenicity ofLDL. Many pathological conditions and environmental factors promote LDL oxidation, especially formation of early forms of oxidized LDL,termed minimal | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| PALO ALTO INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $58,013 | Grant | Trans-NIH Recovery Act Research Support: This American Recovery and Reinvestment Act Administrative Summer Research Supplement proposes to increase the tempo of research activity in the associated R01 grant (R01 HL082662, An Autoimmune Basis for Pulmonary Hypertension) by hiring a Science Educat | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $150,204 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Molecular machines, such as the ribosome or the nuclear pore, are of critical importance for the smooth functioning of the cell. This proposal deals with two issues that are important for the construction of ANY molecu | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $321,529 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): It would be potentially advantageous if organs could be repopulated from a small number of cells that would remove and replace other cells during growth, preserving tissue dimensions during the replacement. Such a proc | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $166,734 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Kinesins comprise a diverse superfamily of over one hundred different proteins, all containing a highly conserved globular catalytic domain with ATPase and microtubule binding activities. Despite the high degree of hom | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $42,720 | Grant | Trans-NIH Recovery Act Research Support: Our studies will provide important animal models and biochemical data to further understand the function of testis-specific protein, Y-encoded-like 1 (TSPYL1) and fetal gamma inducing factor (FGIF) proteins in up-regulating gamma-globin gene expression du | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| MAYO CLINIC | $99,323 | Grant | Trans-NIH Recovery Act Research Support: We are requesting one year's support to retain a post-doctoral research fellow under the American Recovery and Reinvestment Act (ARRA) Administrative Supplement to parent grant R01-EB002834. This capable young scientist has served one year in the Principa | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF WASHINGTON | $310,192 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of R01 EB2991 is to develop new drug delivery systems for biomolecular drugs that must reach intracellular targets for efficacy. The grant is focused on developing and optimizing pH-responsive carriers for anti-neoplastic siRNA dr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $36,830 | Grant | Trans-NIH Recovery Act Research Support: Antagonists used for positron emission tomographic (PET) studies of dopamine D2/D3 receptors do not distinguish between the high-affinity (HA) and low-affinity (LA) states of the receptors. We and others have now accomplished imaging only the HA-state of | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| CATHOLIC HEALTHCARE WEST | $11,724 | Grant | Trans-NIH Recovery Act Research Support: NOT-OD-09-060 (Crawford, Neil) Admin. Suppl. Notice for Students and Science Educators under the Recovery Act | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF MARYLAND | $217,911 | Grant | Trans-NIH Recovery Act Research Support: The objectives of the parent grant EB 006521 are to use a combination of theory, nanofabrication and spectroscopy to develop defined nanostructures which result in enhanced and/or directional fluorescence from surface-bound fluorophores. These defined str | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| WASHINGTON STATE UNIVERSITY | $234,192 | Grant | Trans-NIH Recovery Act Research Support: Resorbable Calcium Phosphate Ceramics for Bone Graft Abstract Calcium phosphate (CaP) based ceramics are used in hard tissue engineering because of their excellent biocompatibility. There is a need for the development of biodegradable ceramic materials wi | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| WAKE FOREST UNIVERSITY | $38,766 | Grant | Trans-NIH Recovery Act Research Support: Diabetes mellitus is a growing problem worldwide. In the US it affects over 18 million people and results in annual health care costs exceeding $130 billion. Insulin therapy of Type 1 diabetes, and in advanced cases of Type 2 diabetes, does not prevent se | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF ROCHESTER | $31,521 | Grant | Trans-NIH Recovery Act Research Support: The summer research experiences for undergraduates will provide numerous avenues to encourage students to pursue research careers in health-related sciences. Opportunities include project and career mentoring, lab meetings, journal clubs, and seminar prog | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| OAKLAND UNIVERSITY | $154,277 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of this award is to study magnetic forces on electric currents in biological tissue, and to analyze and develop new imaging techniques that use these magneto-acoustic effects. In the last two decades, many researchers have proposed magnet | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF SOUTH ALABAMA | $196,610 | Grant | Trans-NIH Recovery Act Research Support: This application is a supplement for NIEHS R01 ES003456, which has been continuously funded for over 24 years. This grant currently funds work to develop fusion proteins which target DNA repair enzymes to mitochondria in an effort to enhance the yield of | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $294,592 | Grant | Trans-NIH Recovery Act Research Support: Many environmental toxins are oxidants. Proteins, which are major targets of oxidative modification, loose function/activity and must be proteolyticaly degraded or they will aggregate, and form cross-linked cellular inclusion bodies. In previous cycles of | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| MICHIGAN STATE UNIVERSITY | $188,365 | Grant | Trans-NIH Recovery Act Research Support: The capacity of modest inflammation to potentiate hepatotoxic responses to drugs (e.g., ranitidine) and other xenobiotic agents has been characterized in several animal models. A common finding is that both neutrophils (PMNs) and hemostasis with consequen | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| WAYNE STATE UNIVERSITY (INC) | $357,461 | Grant | Trans-NIH Recovery Act Research Support: As a major detoxicating enzyme in human liver, hydroxysteroid sulfotransferase (nomenclature: SULT2A is hydroxysteroid sulfotransferase; SULT2A1 is human SULT2A) catalyzes the sulfonation of biologically important endogenous and xenobiotic substrates, inc | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $15,400 | Grant | Trans-NIH Recovery Act Research Support: The objective of this study is to elucidate the mechanism by which testosterone inhibits spermatogonial differentiation after toxicant exposure of rats. Radiation will be used as a model toxicant in most studies and the relevance to chemical toxicants wil | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $115,178 | Grant | Trans-NIH Recovery Act Research Support: Our working hypothesis in the parent grant was that inorganic arsenic (iAs) disrupts gene activation from steroid hormone-regulated gene promoters by changing patterns of histone modification. Our goal was to identify mechanisms disrupted by iAs that are | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF WASHINGTON | $99,950 | Grant | Trans-NIH Recovery Act Research Support: We propose to elucidate molecular mechanisms underlying paraquat-induced dopamine neuron death in vitro and in vivo. We also propose to identify neuroprotective growth factors and elucidate downstream protective mechanisms against paraquat neurotoxicity. | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF FLORIDA | $15,341 | Grant | Trans-NIH Recovery Act Research Support: The Pharmacoxtoxicology of Treichloroethylene Metabolites Study Specific Aims: For several years we have researched the kinetics, metabolism and human toxicology of dichloroacetate | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $74,880 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement to the ongoing study of developmental pesticide exposure in ADHD is designed to support a minority graduate student, Ms. Ashley Green, that has been working on the project. Ms. Green is performing research on epigenetic changes tha | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $287,050 | Grant | Trans-NIH Recovery Act Research Support: Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), chlorobenzenes and dioxins remain an environmental health threat. New and innovative ways of detoxifying these compounds removing them from the environment are needed. This | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $314,437 | Grant | Trans-NIH Recovery Act Research Support: While the specific aims of this grant have not changed, the experiments during this first year have revealed that the level and method of BPA dose administration should be altered to better simulate the free BPA levels that are now known to occur in human | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF PITTSBURGH THE | $348,069 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies will test specific hypotheses about the mechanism and the role of Rho GTPases in the differential regulation of corneal epithelial cell cycle progression (proliferation) and corneal stromal cell activation that are critical in the nor | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| NEW YORK UNIVERSITY | $239,459 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides project support, both for a postdoctoral scientist and equipment, to accelerate the pace of the research. Disorders of the visual nervous system are a major cause of visual disability, and many disorders affect parts of the brain | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $85,585 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this ARRA-funded project is to understand how ion channels determine the contribution of retinal ganglion cells to vision. Experiments are designed to identify and analyze mechanisms of ion channel regulation and neurotransmitter | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $308,000 | Grant | Trans-NIH Recovery Act Research Support: Glaucoma remains a major blinding disease affecting over 66 million persons worldwide. This project has focused on the molecular mechanism(s) by which laser trabeculoplasty (LTP) ameliorates the elevated intraocular pressure (IOP) associated with most of | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF ILLINOIS | $218,430 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the currently active NEI-funded parent project is to determine the causes and consequences of spatiotemporal contrast processing deficits in individuals with retinitis pigmentosa (RP), a group of night-blinding retinal degenerations th | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $288,108 | Grant | Trans-NIH Recovery Act Research Support: Our purpose in carrying out these studies is to understand the molecular causes of and to improve treatments for recurrent corneal erosions and corneal epithelial stem cell deficiency. Trauma-induced recurrent erosions to the cornea cause pain and sufferi | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA BARBARA | $126,134 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to replace two pieces of equipment and to provide a salary for a laboratory assistant. The equipment includes a cryostat and a freezer, both central components of our research laboratory supporting activiti | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| MICHIGAN STATE UNIVERSITY | $229,578 | Grant | Trans-NIH Recovery Act Research Support: Glaucoma is a disease of the visual system often characterized by pressure-induced damage to the optic nerve. This results not only in a loss of ganglion cells from the retina, but also degeneration of their target neurons in the lateral geniculate nucleu | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $185,209 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of the grant are to determine the role of visual experience in the development of the retinotectal system. We have used in VIVO 2 photon imaging and electrophysiology to address these questions and now propose to significantly enhance th | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF MARYLAND | $44,046 | Grant | Trans-NIH Recovery Act Research Support: Success of corneal transplant is dependent on high corneal endothelial (CE) cell density maintained immediately after surgery and thereafter. CE cells die either by acute necrosis, which initiates detrimental inflammatory responses, or by a slow programme | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF MARYLAND | $148,230 | Grant | Trans-NIH Recovery Act Research Support: Success of corneal transplant is dependent on high corneal endothelial (CE) cell density maintained immediately after surgery and thereafter. CE cells die either by acute necrosis, which initiates detrimental inflammatory responses, or by a slow programme | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF WASHINGTON | $227,070 | Grant | Trans-NIH Recovery Act Research Support: This is a request for an administrative supplement to RO1 EY11733 (NEI/NIH). The goals of the parent grant are to determine the effects of aging and oxidative damage in the development of age-related and x-ray caused cataracts. Under the requested supplem | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF KENTUCKY | $60,215 | Grant | Trans-NIH Recovery Act Research Support: The ocular motor system is arguably the best understood mammalian motor system. However, the extraocular muscles, its effector arms, remain somewhat of a black box. From a peculiar phenotype and extreme functional profile, to a disparate response to some | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| SANOVICH, ELENA | $30,600 | Contract | : Recruit Scientific Reviewers and Prepare Summary Statements for National Institute of Health Grants | Health and Human Services, Department of / National Institutes of Health | 7/08/2009 |
| JAMES F TAYLOR DVM | $48,000 | Contract | : Professional services contract to review NIH grant documents. | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $132,662 | Grant | Trans-NIH Recovery Act Research Support: An award was made though the American Recovery and Reinvestment Act of 2009 to directly address two of the Acts objectives: 1) to accelerate our achieving the IRACDA programs goal to train a next generation of researchers who will increase diversity in b | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| ALBANY MEDICAL COLLEGE | $108,000 | Grant | Trans-NIH Recovery Act Research Support: Overall, this ARRA award will support 1 year of salary for a postdoctoral fellow and a substantial amount of supplies to work on an NIH-funded research project. The overall objective of the parent NIH grant that encompass this supplement is to test the | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| BRADLEY, EMMA PENDLETON HOSPITAL | $203,921 | Grant | Trans-NIH Recovery Act Research Support: Although bipolar disorder (BD) is among the most significant health problems for American adults, causing great morbidity, mortality, and over $40 billion per year in healthcare expenditures, we know far less about BD in children and adolescents 1. Pedia | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF MARYLAND | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The candidate is a promising young investigator with board certifications in Internal Medicine and Infectious Disease, and a Masters of Science degree in Clinical Investigation, who has made a substantial commitment to an academic career in patient-orient | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement for a parent grant Characterization of dendritic cells in psoriasis and the effects of efalizumab, 1K23AR052404. The goals of the parent grant are to study the dendritic cells (DCs) in the skin and blood in normal volu | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $69,120 | Grant | Trans-NIH Recovery Act Research Support: Non-Hodgkin's lymphomas (NHLs) are the 5th most common malignancy in the United States, with an incidence that has increased significantly over the last decade. Preliminary data obtained from Adult Lymphoma clinic at DFCI, as well as from Hodgkin's lympho | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| MAYO CLINIC | $53,783 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement will allow an increase in the recruitment of a general population cohort from 400 participants to 600 participant over the next 2 years. This will translate into a relevant improvement in statistical power for comparing renal | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $109,616 | Grant | Trans-NIH Recovery Act Research Support: Given the plateau in progress made with conventional treatment modalities for many cancers, novel treatment modalities need to be developed. Immunotherapy is an example. Over the past 8 years the Candidate has built an effective infrastructure for conduct | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $332,740 | Grant | Trans-NIH Recovery Act Research Support: The cellular immune system holds much potential for mediating antitumor responses in cancer patients. Melanoma is particularly appealing to study immunotherapy, since several melanoma-specific antigens recognized by T cells have been identified over the p | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $287,571 | Grant | Trans-NIH Recovery Act Research Support: Melanoma RAS/BRAF Mutation: Heterogeneity-Risk-Prognosis (R01CA112243; PI: Thomas) Administrative Supplement. This study is an international population-based, case-only melanoma study nested in the Genes, Environment and Melanoma (GEM) study (U01-CA8318 | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $125,662 | Grant | Trans-NIH Recovery Act Research Support: Mutations in the NF2 tumor suppressor gene underlie Neurofibromatosis type 2 (NF2), a familial cancer syndrome featuring the development of central nervous system tumors. The NF2-encoded protein, Merlin, is closely related to the ERM (Ezrin, Radixin and M | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $294,939 | Grant | Trans-NIH Recovery Act Research Support: This adminstrative supplement is for resequencing and additional genotyping. The supplement will enable the retention of laboratory personnel and enable accelerated progress of the grant, as well as provide preliminary data for other grant funding. | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $162,773 | Grant | Trans-NIH Recovery Act Research Support: Occupational exposure to arylamines used in the manufacturing of industrial dyes was the first known cause of human bladder cancer. These carcinogenic arylamines, specifically, 4-aminobiphenyl (4-ABP), beta-naphthylamine, and benzidine, are also contained | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Pancreatic ductal adenocarcinoma is the fourth most common cause of cancer-related mortality in the United States, accounting for nearly 31,000 deaths each year. The vast majority of patients present with locally advanced or unresectable disease, and curr | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $65,725 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to NCI grant R01CA120185 provided funds to purchase an Applied Biosystems (ABI) 7900HT real-time PCR machine which allows direct measurements of gene expression in cells and tissues. | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| DREXEL UNIVERSITY | $306,072 | Grant | Trans-NIH Recovery Act Research Support: This research grant will attempt to identify all the serum glycoproteins that have increased levels of fucosylation in the sera of patients with hepatocellular carcinoma (HCC). It is acknowledged in the literature that changes in glycosylation occur with | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OKLAHOMA STATE UNIVERSITY | $104,360 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of this project are: 1) to identify new natural product inhibitors of Hsp90, libraries of natural products and their derivatives will be screened for their ability to inhibit the Hsp90- dependent refolding of luciferase and Hsp90's ATPas | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $222,278 | Grant | Trans-NIH Recovery Act Research Support: This work develops and applies new advanced methods of imaging, or 'seeing', the structures of proteins and how they work, very much in the spirit of the development of, for example, magnetic resonance imaging methods developed in the last century. The fr | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF FLORIDA | $64,503 | Grant | Trans-NIH Recovery Act Research Support: This Award supports Fellowship Training for Joseph Dzierzewski. A brief description of Mr. Dzierzewski's training program and the research he is conducting as part of this fellowship are provided (both are taken from his NRSA Application). Mr. Dzierzews | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $111,208 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to identify networks within the brain that are involved in attention and memory and evaluate how these networks may change due to normal aging. Differences in the connectivity and functionality of networks subserving attention | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF CALIFORNIA, LOS ANGELES | $425,000 | Grant | Trans-NIH Recovery Act Research Support: Good, Green, Safe Jobs: Promoting worker health and safety on ARRA and green job projects The award funds three university-based programsG??UCLA-LOSH, UCB-LOHP and the University of WashingtonG??through a supplement to the existing HazMat Training Cooper | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $299,000 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this ARRA Administrative Supplement is to plan for the development of a Minority Biospecimens/Biobanking Geographic Management Program (BMaP) hub for Region 6. First, a project coordinator and a graduate student research assistant will be h | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| WASHINGTON UNIVERSITY, THE | $283,295 | Grant | Trans-NIH Recovery Act Research Support: Understanding regulatory mechanisms that maintain pluripotent embryonic cells and control differentiation has fundamental relevance to scientific areas central to human health and disease, including stem cell, developmental, and cancer biology. The novel | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| IOWA STATE UNIVERSITY | $193,008 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to the existing award # 2 R01 GM067104. All viruses must take over the host's protein synthesis (translation) machinery. Cellular mRNAs require a 5' cap and poly(A) tail to recruit the ribosome and initiate translation in a reg | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $266,900 | Grant | Trans-NIH Recovery Act Research Support: Our specific aims are to 1) Investigate the mechanisms through which viral proteins disrupt the mRNA export machinery; 2) To study regulation of mRNA export by antagonists of viral-mediated mRNA export block; and 3) To determine the role of mRNA export i | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $268,346 | Grant | Trans-NIH Recovery Act Research Support: Cells and tissues establish and maintain their unique architectures in large part through the tight regulation of protein and membrane transport. One key aspect of this process is endocytic recycling, the selective return of internalized macromolecules to | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MASSACHUSETTS | $619,702 | Grant | Trans-NIH Recovery Act Research Support: The response of macrophages to infectious microorganisms is enhanced by interferon (IFN) gamma through gene expression modulation, which results in an increased ability to respond to infection. We have shown that the local production of IFNgamma in the he | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| UNIVERSITY OF MASSACHUSETTS | $235,078 | Grant | Trans-NIH Recovery Act Research Support: In our proposed research we will develop a novel approach for magnetically-driven organization of ordered cellular structures without using microfabricated substrates, potentially harmful electrical fields, or the physical attachment to or uptake of mater | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF ILLINOIS | $145,785 | Grant | Trans-NIH Recovery Act Research Support: These supplementary funds will enable us to resolve quickly two problems relating to Aim 1 of our current grant. This Aim seeks to uncover the mechanisms by which hydrogen peroxide is formed inside aerobic cells, using E. coli as a model system. We hav | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $73,815 | Grant | Trans-NIH Recovery Act Research Support: Our goal during the past thirty years of NIH funding has been to understand the mechanism of chemotaxis in the Gram-positive bacterium Bacillus subtilis. During the past decade, the realization has emerged that the B. subtilis paradigm might be the ideal | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ILLINOIS | $405,967 | Grant | Trans-NIH Recovery Act Research Support: The research program addresses questions of fundamental importance to human health-biological design rules that determine whether cells respond to chemotactic signals by disrupting intercellular contacts in ways that fundamentally impact the organization | Health and Human Services, Department of / National Institutes of Health | 5/18/2009 |
| UNIVERSITY OF DELAWARE | $430,110 | Grant | Trans-NIH Recovery Act Research Support: This was an NCRR ARRA Supplement for Translational Research to the COBRE on Membrane Protein Production and Characterization.-? It supported the establishment of a new research program in neurodegenerative diseases by David Colby, Ph.D. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF DELAWARE | $979,810 | Grant | Trans-NIH Recovery Act Research Support: This project is the Delaware portion of a regional effort from the Northeast IDeA states (VT, NH, ME, RI and DE) to provide the first fiber-optic backbone through northern New England that connects higher education and biomedical research institutions for | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF DELAWARE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The Delaware INBRE, a statewide collaboration among 5 Delaware academic and clinical institutions, was renewed in April 2009 for another five years. The biomedical focus of the Delaware INBRE is on cancer, neurosciences and cardiovascular research. Under | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $1,416,666 | Grant | Trans-NIH Recovery Act Research Support: Our hypothesis is that by expanding our nascent Neuro-Oncology research program, we will form a Core that will lead to a better understanding the biology of pediatric brain tumors. We will use funds from this P30 to recruit and support new assistant prof | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $96,176 | Grant | Trans-NIH Recovery Act Research Support: Grant name: Novel small-molecule therapies for CF (Supplement). The purpose of this project is to develop and apply a high-throughput screening assay to identify small-molecule inhibitors and disrupters of Pseudomonas biofilms. The goal is to develop a | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| NORTHEASTERN UNIVERSITY | $156,000 | Grant | Trans-NIH Recovery Act Research Support: Visual Casual Models in Clinical Explanation | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $182,794 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to make feasible the clinical translation of experimental fetal cardiac surgery, i.e., open-heart surgery in utero, for babies affected with the most severe congenital heart defects. Despite continuing efforts, the m | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $7,500 | Grant | Trans-NIH Recovery Act Research Support: This Recovery Act supplement award supported one undergraduate student to work on part of aim 1 of the parent R21 grant for 10 weeks from May to August 2009. Recruitment of the summer student was done through the highly competitive Cincinnati ChildrenG??s | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| CHILDREN'S HOSPITAL MEDICAL CENTER | $412,501 | Grant | Trans-NIH Recovery Act Research Support: The proposed research focuses on innovative, preclinical therapies for the variants of Gaucher disease, a rare, but not uncommon, inborn error of metabolism. The proposed studies use our unique mouse models of Gaucher disease to address the hypotheses tha | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $346,114 | Grant | Trans-NIH Recovery Act Research Support: This ARRA grant for project titled 'Cervical spinal injury and demyelination in aged rats' will develop a model for cervical spinal stenosis and compression injury in aging using a newly-designed spinal compression device in young versus older rats and wi | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| ARIZONA STATE UNIVERSITY | $366,708 | Grant | Trans-NIH Recovery Act Research Support: Most persons diagnosed with cancer do not report a single symptom; instead they have multiple symptoms associated with the disease and treatment. The interactive and cumulative effect of multiple symptoms adversely affects quality of life. Three or more s | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| ARIZONA STATE UNIVERSITY | $381,898 | Grant | Trans-NIH Recovery Act Research Support: Peers and peer networks are important proximal social influences across the lifespan starting at an early age, and, from a developmental perspective, few other microsystemic contexts are as important to children's healthy development. Indeed, the extent t | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| METAMEDIA TRAINING INTERNATIONAL, INC. | $46,737 | Grant | Trans-NIH Recovery Act Research Support: HazMat IQ Four Step System eLearning | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| PHYLONIX PHARMACEUTICALS, INC. | $49,280 | Grant | Trans-NIH Recovery Act Research Support: NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| APTAMATRIX, INC. | $163,249 | Grant | Trans-NIH Recovery Act Research Support: This Phase II project aims at further advancing and commercializing a microarray-based screening approach, for discovering nucleic acid probes that have high affinity and high specificity for protein and cellular targets. Oligonucleotides discovered in th | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| ELECTRONIC BIOSCIENCES | $198,083 | Grant | Trans-NIH Recovery Act Research Support: The goal of this NIH Phase II SBIR Administrative Supplement program is to further develop and demonstrate the capabilities of Electronic Bio Sciences' low noise ion channel measurement system. The system will be further modified from the version develop | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTHCARE AT TYLER | $347,990 | Grant | Trans-NIH Recovery Act Research Support: Tuberculosis remains a major global public health crisis despite being a curable disease. One characteristic feature of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is its slow growth. Mtb employs multiple regulatory networks for | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $394,857 | Grant | Trans-NIH Recovery Act Research Support: Varicella zoster virus (VZV) is the causative agent of chicken pox and shingles. The overall objective of this proposal is to understand the nature of physical and functional interactions between the complex VZV major transactivator, IE62, and specific co | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| HENRY FORD HEALTH SYSTEM | $744,233 | Grant | Trans-NIH Recovery Act Research Support: The goal of this research was to follow up the families in an established multi-ethnic birth cohort by phone interview when the subject children are turning 3-7 yrs of age to ascertain the incidence of asthma and allergic conditions and longitudinal data | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $42,241 | Grant | Trans-NIH Recovery Act Research Support: In an effort to enhance information and communication technologies for our ongoing ICOHRTA research training program, Training for Evidence-Based Health Care Research, Argentina, we will develop and implement a distance-learning course on the complementar | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $43,200 | Grant | Trans-NIH Recovery Act Research Support: Funds are being used to develop and implement new communication and information technologies to track infectious diseases in communities. We are developing 1) an electronic tracking system to collect, process, file, store and retrieve thousands of clinica | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $43,200 | Grant | Trans-NIH Recovery Act Research Support: This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of Zimbabwe (UZ). The program faculty at both institutions are experienced | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $68,201 | Grant | Trans-NIH Recovery Act Research Support: With the growing number of emerging infectious diseases and global threats such as HIV/AIDS, tuberculosis, malaria and bio-terrorism, a firm understanding of infectious diseases and microbiology is critical for all healthcare professionals. However, gaini | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF TEXAS AT ARLINGTON | $66,200 | Grant | Trans-NIH Recovery Act Research Support: This supplement enables a larger sample to be served allowing a more powerful and sophisticated message to be delivered. The additional fudns will be used to hire a new staff member with a masters degree in Social Work. In addition, the requested funds wi | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| PONCE MEDICAL SCHOOL FOUNDATION INC | $502,318 | Grant | Trans-NIH Recovery Act Research Support: The RCMI program of Ponce School of Medicine (PSM) is in its 18th year of funding. Currently, the program is funded for a period of 3 years to encourage accelerated implementation of some of the programs that were deemed promising. In order to further imp | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF PUERTO RICO-MEDICAL SCIENCES CAMPUS | $599,065 | Grant | Trans-NIH Recovery Act Research Support: ARRA Supplement Rationale. We are currently initiating the second, and in many ways more challenging phase of this project, i.e. to engage and empower investigators who have little or no experience with approaches and methods of neurogenetics Specific A | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| RANGER GROUP LLC, THE | $4,167,996 | Contract | : Recovery Act -- Repair & Upgrade Switchgear -- Building 31B | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $111,851 | Grant | Trans-NIH Recovery Act Research Support: Aim: To evaluate the role of p38 MAPK in subsets of MDS based on epigenomic profiles We had proposed correlating in vitro responses to p38 inhibition with MDS disease characteristics and cytogenetics in the original grant submission. Since then we have d | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $1,632,440 | Grant | Trans-NIH Recovery Act Research Support: Individuals of similar body size may differ widely in their risk of cardiovascular disease (CVD), suggesting that factors other than body mass index or total body adiposity are key determinants of adiposity-associated CVD risk. Deposition of triglyceride | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $105,820 | Grant | Trans-NIH Recovery Act Research Support: Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator found in high levels in the blood. Signaling by S1P through its G protein-coupled receptor S1P1 is critical for the emigration of T cells from lymphoid organs into circulation. FTY720, a drug tha | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $108,000 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application is to use the zebrafish to identify novel pathways that regulate stem cell self- renewal in both normal muscle and embryonal rhabdomyosarcoma (ERMS), a pediatric malignancy of muscle. The zebrafish, with its close synteny to t | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SUTTER WEST BAY HOSPITALS | $35,622 | Grant | Trans-NIH Recovery Act Research Support: Project Summary A) Scope of the overall project and the anticipated contribution of the requested supplement. I requested to increase the hours of our current part-time staff to full-time in 2010. The requested supplement will be used as outlined in Sp | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $97,667 | Grant | Trans-NIH Recovery Act Research Support: Cancer prevention is the most effective strategy to reduce cancer morbidity and mortality. Therefore, it is imperative to develop new investigators in this area of research. Yan Dong, a junior investigator in the field of cancer chemoprevention, has exten | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF ILLINOIS | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the proposed administrative supplement is to bring advanced technology to understand the molecular and functional interaction of ANP and NO signaling , to achieve certain new research objectives within approved scope of the parent KO1 | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF LOUISVILLE | $50,710 | Grant | Trans-NIH Recovery Act Research Support: The candidate's overall career goal is to establish an independent research program devoted to investigating cellular mechanisms of proteinuric nephropathies, with an emphasis on diabetic nephropathy (DN). Currently, DN is the leading cause of end stage r | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $103,474 | Grant | Trans-NIH Recovery Act Research Support: PTSD and Dual Disorders at the Interface of the MH and CJ Systems ARRA The purpose of this ARRA-funded project is to accelerate the tempo of the NIMH-funded intervention study for PTSD and substance use disorders. The additional funding allowed us to hir | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WASHINGTON | $31,048 | Grant | Trans-NIH Recovery Act Research Support: BACKGROUND: Extensive variability has been noted among pathologists in the diagnosis of cancer and the number one reason for medical malpractice in the U.S. is failure to diagnose breast cancer. There is little published information about how pathologis | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $108,000 | Grant | Trans-NIH Recovery Act Research Support: My current research agenda falls into two main areas. The first area is my focus on a population-based approach to examining the quality of care for women with breast cancer. The second area is the evaluation of online communication and service tools to i | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $48,963 | Grant | Trans-NIH Recovery Act Research Support: The objective of this career development award is to provide Dr. Sharon Giordano with the experience and knowledge necessary to become an independent health services researcher in the field of breast cancer. Dr. Giordano, who is a medical oncologist and M | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $95,414 | Grant | Trans-NIH Recovery Act Research Support: This Research Career Award application is intended to provide research experience and career development opportunities to a new investigator whose career aspiration is to advance the understanding of the epidemiology and prevention of blood-related cancer | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| WAYNE STATE UNIVERSITY (INC) | $106,046 | Grant | Trans-NIH Recovery Act Research Support: The parent study for this supplement, Oxidative Stress, Antioxidants and Racial Disparities in Prostate Cancer (1K07 CA119109-01A2) is a mentored career development award sponsored by NCI. The main goals of the parent study are to develop the PIG??s poten | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $90,217 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this K07 application is to build a mentored research and training experience to foster independent professional development in obesity and cancer prevention, specifically focusing on the understudied area of excess weight gain among college | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $85,482 | Grant | Trans-NIH Recovery Act Research Support: This pharmaco-epidemiologic study evaluates the chemopreventive potential of statins in malignant glioma and to assess pharmacogenetics as risk-modifiers. The design is a case-control study that recruits malignant glioma cases and matched controls. At Col | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NEW YORK UNIVERSITY (INC) | $103,968 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement is providing monies to support one part-time (60%) laboratory technician to perform genotyping, bisulfite modification and sequencing to test the hypotheses outlined in the parent grant K07 CA131094. The laboratory technicia | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| GEORGETOWN UNIVERSITY (THE) | $100,957 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this career development application is to provide a mentored training and research experience to become an independent cancer control investigator with a focus on genomic medicine and cancer risk. Genomic information and personalized geneti | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $48,527 | Grant | Trans-NIH Recovery Act Research Support: FOXP3 Structure, Function and Regulatory Activity in T cells -- The transcription factor FOXP3 is required for development of functional CD4+CD25+ regulatory T cells (Treg). Mutations in FOXP3 lead to a severe systemic autoimmune phenotype in both huma | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF CHICAGO, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Dr. Yu's long term goal is to understand how the immune system responds to syngeneic cancerous cells and tissues, and how stronger immune responses can be promoted against the malignancies. The current application is intended to uncover the mechanisms of | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF IOWA, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: This application is to provide support for a supervised research career development experience for Dr. David Stoltz in the field of airway cell biology. Dr. Stoltz has completed a combined M.D./Ph.D. program and is currently in the Pulmonary/Critical Care | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $40,983 | Grant | Trans-NIH Recovery Act Research Support: This proposal focuses on understanding the mechanism of GM-CSF-induced sVEGFR-1 production from mononuclear phagocytes and the resulting anti-tumor activity therein. Our data indicates when normal FVB/N female mice are injected with PyMT tumor cells and f | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF NEW MEXICO | $44,388 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): My long-term career goal is to become a faculty member at an academic center where I will investigate the contribution of microRNAs (miRNAs) to ovarian cancer metastasis. My current career goals are to build an indepen | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $54,000 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement will accelerate research on how single neurons in the frontal cortex and the caudate nucleus reflect visual perceptual decision-making with different reward schedules. This research will identify neural correlates of perceptual dec | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $78,684 | Grant | Trans-NIH Recovery Act Research Support: PROJECT SUMMARY (See instructions): The purpose of this supplement request, under NOT-OD-09-060, is to provide meaningful hands-on research experience to undergraduate students interested in pursuing research careers in health-related sciences, while at t | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $355,465 | Grant | Trans-NIH Recovery Act Research Support: The overarching goal of this Program is to understand the molecular mechanisms that regulate cell activation. Activation of lymphocytes through specific recognition of antigen poses narrowly balanced benefits and risks, and hence is subject to tight regul | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $214,502 | Grant | Trans-NIH Recovery Act Research Support: Biological treatment strategies by growth factor and Cytokine inhibitors -Overall goals are to understand the biological mechanisms of Discogenic back pain in patients and test out biological therapeutics in our rabbit disc degeneration model. | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $215,373 | Grant | Trans-NIH Recovery Act Research Support: The equipment requested will speed up our ability to test eyebrow and tumor tissue for HPV DNA and will insure that tissue cultures needed in project 2 can continue. The additional personnel will help project 1 meet the enrollment deadlines, request tiss | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $396,040 | Grant | Trans-NIH Recovery Act Research Support: The parent Program G?Prospective Studies of Diet and Cancer in Men and WomenG? (2P01CA055075) supports the continued follow-up of 51,529 men who have completed extensive dietary questionnaires every four years since 1986 (the Health Professionals Follow-u | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $165,127 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Program Project Grant (PPG) P01 CA1000730 Supplement Application is to seek support to enhance and expand a currently funded PPG that utilizes integrated retrovirus models to elucidate basic cellular mechanisms that define lymphocyte t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF PITTSBURGH THE | $137,344 | Grant | Trans-NIH Recovery Act Research Support: To allow the researcher to pursue independence as they investigate the hypothesis that NK cells respond to autophagic flux of the tumor microenvironment and that differences between tumors in this aspect may determine NK cell tumor homing. In addition, th | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE VANDERBILT UNIVERSITY | $320,720 | Grant | Trans-NIH Recovery Act Research Support: Chronic kidney disease is a major health problem in the United States today, as more than 20 million people (1 in 9 adults) have abnormalities in kidney function, and over 400,000 are on renal replacement therapy. The incidence of this condition is rising | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $127,463 | Grant | Trans-NIH Recovery Act Research Support: The nuclear factor kappa B (NF-kB) family of transcription factors controls inter- and intracellular signaling, cellular stress responses, cell growth, survival, and apoptosis. In resting cells, NF-kB dimers with transcription activation potential are seq | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $81,142 | Grant | Trans-NIH Recovery Act Research Support: Chronic pain is a serious health problem that has remained largely refractory to therapeutic intervention. The development of new pain therapeutics would be aided by a better understanding of the molecular and cellular mechanisms mediating nociception. T | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $72,844 | Grant | Trans-NIH Recovery Act Research Support: This supplement supports a Mouse Core (Core B) that is part of the parent Program Project grant. The supplement is requiested to provide funds for two main purposes: 1) to support the additional per diem charges that will accrue from the expansion of e | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY | $129,670 | Grant | Trans-NIH Recovery Act Research Support: MBRS Research Initiative for Scientific Enhancement at North Carolina A&T State NCATG??Summer Opportunity for Academic and Research Enhancement (NCAT-SOARE) Program The goal of the NCAT-Summer Opportunity for Academic and Research Enhancement (NCAT-SOARE | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $256,820 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to upgrade the data management and data base components of our Developing Center for Interventions and Service Research in Bipolar Disorders (DCISR) and utilize the data base developed through the several activities of th | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $472,208 | Grant | Trans-NIH Recovery Act Research Support: This funding will directly sopport translational research projects within the Center for Structural and functional Neuroscience (CSFN) that involve the development of technologies and pharmaceutics to address neurodegenerative disorders resulting from gli | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $176,237 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to advance the mission of the COBRE program through funding for recruitment and retention of technical staff. These positions will support a subset of competitively selected pilot research projects in the Center for Structural and Func | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF RHODE ISLAND | $1,281,537 | Grant | Trans-NIH Recovery Act Research Support: The main purpose of this IDeA Network of Biomedical Research Excellence (INBRE) proposal is to continue to enhance institutional capacity for biomedical and behavioral research in the state of Rhode Island. The University of Rhode Island (URI) is the lead | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF OKLAHOMA | $595,235 | Grant | Trans-NIH Recovery Act Research Support: This project seeks to establish the Program in Community Health Research, a research, training, and faculty development program, dedicated to advancing community-based research to improve the health status of low-income communities and their members in Tu | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| THE UNIVERSITY OF SOUTH DAKOTA | $223,598 | Grant | Trans-NIH Recovery Act Research Support: This funding is to support 12 summer undergraduate research fellows from the University of South Dakota, and 6 disadvantaged high school students from South Dakota. The undergraduates will spend 10 weeks conducting research in a laboratory at USD or one | Health and Human Services, Department of / National Institutes of Health | 6/03/2009 |
| UNIVERSITY OF LOUISVILLE | $969,563 | Grant | Trans-NIH Recovery Act Research Support: The Kentucky INBRE serves a statewide mission to build infrastructure and capacity for biomedical and health-related research and training as well as for bioinformatics. In this application, the University of Louisville is partnered with the University of | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $51,018 | Grant | Trans-NIH Recovery Act Research Support: The goals of this project are to understand the concurrent development of the acoustical cues to sound source location and the neural circuits that encode them. All cues for localization can be captured in measurements of head related directional transfer | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF CONNECTICUT | $299,918 | Grant | Trans-NIH Recovery Act Research Support: Language development in typical children follows specific developmental sequences and demonstrates inherent biases at certain stages. It is not known to what degree language development in children with autism follows the same development rules or achiev | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| GEORGETOWN UNIVERSITY (THE) | $22,227 | Grant | Trans-NIH Recovery Act Research Support: This proposal is to continue to develop, maintain, test, and evaluate the Image-Guided Surgical Toolkit (IGSTK). IGSTK is an open source software project that provides the basic components to develop an image-guided system. The initial version of the soft | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| KANSAS STATE UNIVERSITY | $398,600 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This renewal of the COBRE award to the College of Veterinary Medicine (CVM) at Kansas State University (KSU) is requested for the continued support of the Center for Epithelial Function in Health and Disease. This Cent | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $200,000 | Grant | Trans-NIH Recovery Act Research Support: The LSU School of Dentistry is currently completing the Phase I CoBRE and is poised to pursue phase II in a competitive renewal. The renewal application continues with the theme of ?oral infectious diseases.? Two of the six new specific aims include: (1) | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $154,231 | Grant | Trans-NIH Recovery Act Research Support: The John A. Burns School of Medicine (JABSOM) at the University of Hawaii at Manoa (UH Manoa) is submitting this application in response to National Institutes of Health (NIH) PAR-07-229. With a Center of Biomedical Research Excellence (COBRE) award, we s | Health and Human Services, Department of / National Institutes of Health | 8/23/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO ,THE | $31,711 | Grant | Trans-NIH Recovery Act Research Support: The central premise underlying the San Antonio Nathan Shock Aging Center described in this proposal is that identifying the biological mechanisms that lead to senescence can best be achieved by manipulating the whole organism genetically, nutritionally, o | Health and Human Services, Department of / National Institutes of Health | 7/09/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $50,000 | Grant | Trans-NIH Recovery Act Research Support: Dana Farber/Harvard Cancer Center (DF/HCC) is an inter-institutional research enterprise that unites the major clinical, population, and basic cancer research efforts of the Harvard medical and public health community. It was founded in 1998 through a for | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $49,863 | Grant | Trans-NIH Recovery Act Research Support: The USC/Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Core Support Grant since 1973. It has developed into a major regional and national resource for | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $1,182,020 | Grant | Trans-NIH Recovery Act Research Support: The USC/Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Core Support Grant since 1973. It has developed into a major regional and national resource for | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| DUKE UNIVERSITY | $1,518,013 | Grant | Trans-NIH Recovery Act Research Support: Colorectal cancer is the third most common cancer and the second leading cause of cancer related death in the United States. 75% of patients diagnosed with colorectal cancer will have early stage disease and despite surgical resection for curative intent, | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HEALTH RESEARCH, INC. | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The Roswell Park Cancer Institute (RPCI) has been continuously recognized as a Comprehensive Cancer Center since the NCI designation of such centers in 1974 and is now requesting continued federal support for the next five years. A free-standing research, | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $2,674,939 | Grant | Trans-NIH Recovery Act Research Support: The joint recruitment of a Physician Scientist into the Departments of Medicine and Cancer Biology will complement and synergize with the current faculty and research strengths to broaden the ACC expertise in tumor metabolism or tumor immunology. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by: 1) conduct | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| CARL ZEISS MICROIMAGING, INC. | $14,348 | Contract | : Laboratory Equipment | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| PALLADIAN PARTNERS, INC. | $363,760 | Contract | : Develop real life stories that underscore job and infrastructure related to ARRA research findings. | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WELLS JR, WILLIAM G | $19,500 | Contract | : Provision of Grants Management Support to the OGCM/NINR for ARRA grant projects. Includes coordination of ARRA funding and reporting requirements, review ARRA grant applications for compliance with NIH and NINR policy and negotiation and preparation of g | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| NEXCELOM BIOSCIENCE LLC | $9,320 | Contract | : Laboratory equipment and supplies | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| CONTEMPORARIES, INC. | $91,910 | Contract | : WEB DEVELOPMENT SUPPORT SERVICES ON THE COLLABORATIVE PROJECT BETWEEN OCLA & CBI FOR THE NHLBI ARRA WEBSITE WITH VIDEO BLOGGING | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE | $16,872,951 | Contract | : To design and test a method of intervention that has the capacity to promote engagement and adherence to treatment, foster recovery and reduce or prevent disability in patients experiencing a first episode of schizophrenia and related psychotic disorders. | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $46,537 | Grant | Trans-NIH Recovery Act Research Support: We will characterize the structure and function of Vomp adhesins of the human pathogen Bartonella quintana to better understand how this emerging pathogen causes disease in humans and identify novel strategies to combat B. quintana infection. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $48,598 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to a K23 project entitled Impact of HIV on the T cell repertoire. The parent project is a cross-sectional study of the effect of HIV infection on T cell diversity. Loss of T cell diversity is thought to play an important role in the | Health and Human Services, Department of / National Institutes of Health | 8/02/2010 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $54,000 | Grant | Trans-NIH Recovery Act Research Support: This is a supplement to parent grant K23DK077734 to increase the hours of the research coordinator. The increased hours allowed the coordinator to extend clinic sessions, enrolled more patients, etc. All funding was spent as of last quarter. The parent | Health and Human Services, Department of / National Institutes of Health | 8/24/2009 |
| UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | $99,986 | Grant | Trans-NIH Recovery Act Research Support: This project is to enhance research proposed in the original grant by investigating the persistent and on-going injuries in acutely ACL-injured knees using larger cohort of patients and longer follow up after surgeries using MR T1rho mapping techniques. T | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $365,042 | Grant | Trans-NIH Recovery Act Research Support: The University of Colorado Cancer Center (UCCC) is the only NCI-designated comprehensive Cancer Center in the Rocky Mountain region - an area with a population of approximately eight million people. The goals are to reduce the cancer burden by: 1) conduct | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF PITTSBURGH THE | $246,317 | Grant | Trans-NIH Recovery Act Research Support: UPCI has been developing a Small Animal Imaging Facility as an additional component of the In Vivo Imaging Shared Facility, a part of the Cancer Center Support Grant (CCSG). This Administrative Supplement entitled Contrast Enhanced Ultrasound Imaging of V | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $1,299,007 | Grant | Trans-NIH Recovery Act Research Support: The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $145,089 | Grant | Trans-NIH Recovery Act Research Support: Establishment of a two year training program in translational cancer research for High School science teachers (grades 9-12) in New Brunswick School District and others across New Jersey and faculty at regional community colleges in New Jersey. This prog | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF IOWA, THE | $298,623 | Grant | Trans-NIH Recovery Act Research Support: The University of Iowa Holden Comprehensive Cancer Center (HCCC), a matrix cancer center at the University of Iowa, is applying for renewal of its Cancer Center Support grant. This is the first competitive renewal application for the HCCC. The Cancer Cent | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $49,998 | Grant | Trans-NIH Recovery Act Research Support: The Stanford Cancer Center will participate in the planning activities associated with the new initiative entitled ADPOTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT), by providing appropriate clinical and informatics expe | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BAYLOR COLLEGE OF MEDICINE | $50,000 | Grant | Trans-NIH Recovery Act Research Support: ADOPTion of New Technologies for Remote Data Capture and Protocol Authoring (ADOPT) which is intended to improve the efficiency and effectiveness of the clinical process and reduce clinical trial costs. The Dan L. Duncan Cancer Center (DLDCC) will provide | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE HOSPITAL, INC. | $344,103 | Grant | Trans-NIH Recovery Act Research Support: The Moffitt Cancer Center requests an administrative supplement to its Cancer Center Support Grant (5 P30 CA076292-11) to expand the support for the technological platforms offered by the Microarray Core Facility in the area of the genomic evaluation of c | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| BAYLOR COLLEGE OF MEDICINE | $300,000 | Grant | Trans-NIH Recovery Act Research Support: To purchase new equipment to be run by a new-?ly hired technician and provide pilot funds for novel GI-related projects. This AARA Administrative Supplement requests funding to enhance the ability of the Texas Medical Center Digestive Diseases Research Co | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF MARYLAND | $54,360 | Grant | Trans-NIH Recovery Act Research Support: The CNRU of Maryland will focus on the influence of nutrition and exercise on risk for age-related chronic diseases, including obesity, type 2 diabetes, hypertension, cardiovascular disease (CVD), sleep disordered breathing, and osteoporosis. With the obe | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $989,492 | Grant | Trans-NIH Recovery Act Research Support: This supplement is to accelerate Aim 1C in the original application (1C. We will efficiently curate information derived from the literature and user submission) thereby helping achieve Aim 1 (Increase Database Content), and in a new Aim (Aim 3; described | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $495,402 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to 1) accelerate the tempo of the core research and its clinical translation proposed under the parent grant by recruiting additional research personnel and 2) to translate the technologies developed under core research a | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $923,575 | Grant | Trans-NIH Recovery Act Research Support: The aim of this supplement is to support and facilitate a translational application of our ultrahigh magnetic field (7 Tesla) instrumentation and technology. The specific aim is to directly visualize the deep subcortical nuclei and to use this informati | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $340,857 | Grant | Trans-NIH Recovery Act Research Support: Fourier transform ion cyclotron resonance mass spectrometry (FTMS) developments and applications to the analysis of glycans, peptidoglycans, and proteoglycans are an important component of this research resource. There are two specific aims for this core | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $27,854 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for two students: Tiffany Sanchez, an undergraduate student at Columbia University and Larissa Calancie, a college graduate of May'09 from Cornell University. The final progress report was previously sent | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $209,181 | Grant | Trans-NIH Recovery Act Research Support: This Superfund Basic Research and Training Program-Reuse in RI: A State-Based Approach to Complex Exposures-tackles through research and outreach three inter-related thematic challenges: 1) land reuse, 2) a state-based approach, and 3) complex exposures. | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS M D ANDERSON | $117,418 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this University of Texas M. D. Anderson Cancer Center Genitourinary SPORE in Bladder Cancer is to facilitate innovative translational research in the prevention, detection, and treatment of this disease leading to the elimination of bl | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $96,073 | Grant | Trans-NIH Recovery Act Research Support: This is a competing renewal application for the Harvard SPORE in Skin Cancer, originally funded in October of 2001. This SPORE is based at Brigham and Women's Hospital and is part of the Skin Cancer Program of the Dana Farber Harvard Cancer Center. This p | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| BAYLOR COLLEGE OF MEDICINE | $59,392 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for 4 high school students in health-related scientific research. The goal of this program is to expose trainees at the earliest stage of their career to translational research in cell and gene therapy. Thi | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF MIAMI | $231,079 | Grant | Trans-NIH Recovery Act Research Support: The Oceans and Human Health Center at the University of Miami will enhance and accelerate the ongoing research and training at the OHH Center through research focused on harmful algal blooms (HABs) and their toxins, including evaluating the extent of thei | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $224,275 | Grant | Trans-NIH Recovery Act Research Support: We use ELS as a framework to encompass adverse early care conditions: separation/loss, neglect, abuse. We integrate basic developmental behavioral neuroscience using various models to a) increase understanding of the behavioral and neurobiological impacts | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF PITTSBURGH THE | $36,886 | Grant | Trans-NIH Recovery Act Research Support: Neuroprotection and early detection in PD. This core provides services for our Udall center, including ordering, the management of funds, and assistance with the preparation of manuscripts and progress reports. | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MIAMI | $141,930 | Grant | Trans-NIH Recovery Act Research Support: There is overwhelming evidence for a central role of mitochondrial dysfunction in Parkinson's Disease. This project is based upon our report of a significant association of the mitochondrial J and K haplogroups with Parkinson Disease (PD). In the parent g | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF MIAMI | $407,219 | Grant | Trans-NIH Recovery Act Research Support: At different stages of Parkinson's Disease, the pathological changes occur at different critical brain regions. Using genomic convergence approach, gene expression from critical brain region will provide valuable candidate genes for further analysis. As | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| NORTHWESTERN UNIVERSITY | $430,730 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to identify functional variants of environmentally responsive genes that are biologically relevant to motor neuron degeneration of sporadic amyotrophic lateral sclerosis (SALS) and primary lateral sclerosis (PLS). | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $1,372,003 | Grant | Trans-NIH Recovery Act Research Support: This NCRR ARRA supplemental award for the Tulane National Primate Research Center (TNPRC) which was funded in late September 2009 provides funding to support and accelerate translational research efforts at the TNPRC. Funds will be used to hire new empl | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF WASHINGTON | $388,800 | Grant | Trans-NIH Recovery Act Research Support: The Division of Functional Genomics and Infectious Disease at the Washington National Primate Research Center (WaNPRC) seeks supplemental funding to expand the Center's Pilot Project Program in support of innovative research studies. The WaNPRC and Instit | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $598,056 | Grant | Trans-NIH Recovery Act Research Support: Funds are requested to support a post-doc to begin his faculty career as an Instructor at Harvard Medical School to serve at New England Primate Research Center. These funds will be used to pay salary plus fringe for two years, and for 2 research assistan | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $267,433 | Grant | Trans-NIH Recovery Act Research Support: This award enhances the original aims set forth in the NIAMS Multidisciplinary Clinical Research Center proposal entitled, Genetic and Molecular Markers of Methotrexate Efficacy and Toxicity in Early RA (Donna K. Arnett, PhD, Principal Investigator), defi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WASHINGTON UNIVERSITY, THE | $59,408 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to provide funding for summer appointments of undergraduate student researchers to work in laboratories of Washington University Diabetes Research Training Center (DRTC) affiliated investigators. | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $277,045 | Grant | Trans-NIH Recovery Act Research Support: Diabetes Research and Training Center This application is in response to the National Institutes of Health Notice NOT-OD-09-056 (administrative supplement for Research Center Grants). The Baltimore DRTC requests supplemental funding of programs that will | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NEBRASKA | $25,724 | Grant | Trans-NIH Recovery Act Research Support: Interferon regulatory factor 7 (IRF-7) is implicated in the regulation of Epstein-Barr virus (EBV) latency. EBV infection is a leading cause of lymphomas especially in immunocompromised individuals and has been associated with nasopharyngeal carcinoma (N | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $42,902 | Grant | Trans-NIH Recovery Act Research Support: Alcohol consumption during pregnancy is a significant public health problem and may result in a wide range of adverse outcomes for the child. Many of these fetal alcohol exposed children show poor stress tolerance, immune system incompetence, and abnormal | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $169,579 | Grant | Trans-NIH Recovery Act Research Support: This is an application for administrative supplement to my currently active RO1 grant Short-Chain Dehydrogenases (SDRs) in Retinol/Sterol metabolism. The overall goal of this project is to understand the mechanisms that regulate the steady-state levels of | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $90,378 | Grant | Trans-NIH Recovery Act Research Support: The neurosteroid allopregnanolone (ALLO) is a potent positive modulator of GABAA receptors, and evidence suggests that GABAergic neurosteroids are endogenous modulators of GABAA receptors and of selective effects of ethanol (EtOH). The present proposal bu | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $33,638 | Grant | Trans-NIH Recovery Act Research Support: The Fetal Alcohol Effects and Choline Intervention project examines the potential of choline, an essential nutrient, to reduce the severity of neuropathology and behavioral alterations associated with developmental alcohol exposure. Using an animal model | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| ERNEST GALLO CLINIC AND RESEARCH CENTER | $54,072 | Grant | Trans-NIH Recovery Act Research Support: Phosphorylation and the CNS Actions of Ethanol This administrative application is aimed to allow us to purchase a high performing up right microscope that will be used for electrophysiology experiments included in RO1 AA013438 and RO1 AA014366. The micro | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| PACIFIC INSTITUTE FOR RESEARCH AND EVALUATION | $10,461 | Grant | Trans-NIH Recovery Act Research Support: On a typical weekend, more than 7,000 young Americans cross the U.S. border at San Diego into Tijuana, Mexico. PIRE's recent cross-border work reveals that, less than a mile from the border gates, a strip of all night bars caters to young American drinker | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF NEW MEXICO | $252,000 | Grant | Trans-NIH Recovery Act Research Support: In Sioux Falls, two people will be hired to begin working with the Sioux Falls Public Schools to lay the groundwork for eventually in-school screening for developmental disabilities among the general population of first grade children. The hired individua | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $118,846 | Grant | Trans-NIH Recovery Act Research Support: The Scientific Goal of this application is to accelerate the tempo of the affective regulation component of the parent R01 research (Specific Aim 4) by giving us the capability to rapidly test the mechanism underlying our discovery that high amplitude osc | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF ILLINOIS | $252,000 | Grant | Trans-NIH Recovery Act Research Support: Chromatin remodeling occurs due to covalent histone modifications. Two major enzymes, histone acetyltransferases (HATs) and histone deacetylases (HDACs), regulate histone acetylation and deacetylation, respectively. The acetylation of histones leads to a | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $185,689 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this research is to understand the regulation of gene expression during aging using the model organism Drosophila melanogaster. Aging in both flies and humans is found to be associated with a tissue-specific induction of oxidative st | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| RAND CORPORATION. THE | $100,233 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application is for a competing continuation of the currently funded project Internet Interviewing and the HRS. The current project is a joint collaboration between RAND and the University of Michigan. Its broad ob | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $211,302 | Grant | Trans-NIH Recovery Act Research Support: Post-menopausal osteoporosis, a global public health problem, has for decades been attributed solely to declining estrogen levels, and although follicle stimulating hormone (FSH) levels rise sharply in parallel, a direct effect of FSH on the skeleton has | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF WASHINGTON | $91,662 | Grant | Trans-NIH Recovery Act Research Support: This application is for an administrative supplement to Pharmaconeuropathology of Brain Aging and Dementia (R01 AG023810) that exploits the tremendous resources of the Adult Changes in Thought (ACT) study to address the therapeutic imperative for dementia | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $147,547 | Grant | Trans-NIH Recovery Act Research Support: ARRA - Acute Coronary Syndrome Outcomes for Medicare Patients The parent grant for this administrative supplement addresses the comparative effectiveness of alternative revascularization strategies for aged Medicare beneficiaries with acute coronary synd | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $82,543 | Grant | Trans-NIH Recovery Act Research Support: Obesity, insulin resistance, diabetes mellitus, and aging are the leading causes of renal and cardiovascular disease. In addition to the important roles played by hypertension, abnormal carbohydrate metabolism, profibrotic growth factors, proinflammatory | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| UNIVERSITY OF CONNECTICUT | $142,445 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent grant (AG028657) is to define the pathophysiology of detrusor underactivity (DU), a condition present in two-thirds of frail incontinent elderly. Our studies are designed to implicate MIF (macrophage migration inhibitory factor) in | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $31,058 | Grant | Trans-NIH Recovery Act Research Support: University of Alabama at Birmingham (UAB) is one of America's premier research universities, ranking among the top 20 in funding from the NIH and earns more than $610 million per year in contract and grant support from federal agencies. Research enterpri | Health and Human Services, Department of / National Institutes of Health | 8/05/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $366,131 | Grant | Trans-NIH Recovery Act Research Support: All of the pieces of equipment proposed in our application have been purchased and installed (a Veriti 96 Well Thermal Cycler, Alpha Innotech Gel Imaging System and Accuri C6 Flow Cytometer). A Life Science Research Assistant (the position proposed in the | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $32,330 | Grant | Trans-NIH Recovery Act Research Support: An Administrative Supplement is requested to support two undergraduate students. These students will conduct research on the parasite Entamoeba histolytica. They will have project that support the specific aims of the grant: 5 RO1 AI026649-20 Structure an | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $504,000 | Grant | Trans-NIH Recovery Act Research Support: This is an NCRR Competitive Revision Application (NOT-OD-09-058 - 'Enabling RPGs to Leverage NCRR Center and Center-like Programs') submitted as a supplement to R01 AI39480 (Mechanism and function of the regulatory protein LAG-3). The goal of the parent R | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| ALBANY MEDICAL COLLEGE | $400,000 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. The overall objective of this project is to determine the mechanisms required for effe | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $220,740 | Grant | Trans-NIH Recovery Act Research Support: Despite being dependent on the same set of cytokines (IL-+7 and IL-15) for their survival, memory CD4-+ T cells generally display a shorter lifespan than memory coa' T cells. We will test the hypothesis that a reduced competitiveness of memory CD4-+ T cel | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $114,633 | Grant | Trans-NIH Recovery Act Research Support: Malaria continues to expand as a major public health threat throughout the world. The spread of drug resistant malaria and the lack of an effective vaccine make alternative and complementary approaches to malaria control increasingly important. The overal | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC, THE | $555,738 | Grant | Trans-NIH Recovery Act Research Support: The first specific aim of the R01 grant Transmission and Fitness of Drug Resistant HIV-1, AI47033 is to determine the prevalence of transmitted drug resistant variants including those that may be resistant to new antiretroviral targets such as inhibitors | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| PURDUE UNIVERSITY | $98,640 | Grant | Trans-NIH Recovery Act Research Support: The ability to invade non-phagocytic host cells is essential for Salmonella virulence. SipA, SipC, SopB, SopE, and SopE2 are five type III effectors that are known to promote Salmonella invasion by modulating host actin dynamics both directly and indirect | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $18,158 | Grant | Trans-NIH Recovery Act Research Support: The award is a supplement to a NIH-supported project. This fund allows us to provide a research opportunity in the biomedical area for a college student or college graduate. The study will generate novel insights on how Ebolavirus replicates. Ebolavirus i | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SEATTLE BIOMEDICAL RESEARCH INSTITUTE | $17,352 | Grant | Trans-NIH Recovery Act Research Support: This grant provided a summer research experience for one science educator in health-related scientific research. The summer supplement provided salary and supplies for a high school teacher to conduct research related to the parental NIH grant objectives | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $471,000 | Grant | Trans-NIH Recovery Act Research Support: These studies will address the role of therapy-induced immune regulation in the immunology of Multiple Sclerosis. We believe that the results from such an evaluation will provide greater insight into the complex processes that underlie the regulation of | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $21,778 | Grant | Trans-NIH Recovery Act Research Support: Asthma incidence is increasing and warrants investigation of distinct immune mechanisms. Innate, non- antigen-dependent immunity has been shown to play a role in allergic responses. Our data suggest that the innate immune collectin, surfactant (SP-)-D, ca | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| MONTANA STATE UNIVERSITY, INC | $427,500 | Grant | Trans-NIH Recovery Act Research Support: Prion diseases are fatal neurodegenerative diseases of humans and animals. Dissemination in the nervous system occurs by prion agent movement along nerve fibers and transynaptic spread between neurons. The long-term goal of the proposed research is to def | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| FLORIDA STATE UNIVERSITY, THE | $103,450 | Grant | Trans-NIH Recovery Act Research Support: Personnel funds are requested to support an additional half-time compensation for a postdoc (to bring her up to full time support) to process the additional data resulting from our utilization of the electron microscope facility at the University of Texas | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| DUKE UNIVERSITY | $48,060 | Grant | Trans-NIH Recovery Act Research Support: Lipid A (endotoxin) is a glucosamine-based saccharolipid that constitutes the outer monolayer of the outer membrane of Gram-negative bacteria; it is also the active component of lipopolysaccharide that causes life- threatening Gram-negative septic shock. | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE INC | $174,554 | Grant | Trans-NIH Recovery Act Research Support: Campylobacter infections constitute the most common bacterial form of gastroenteritis in the US, however, an effective vaccine against campylobacteriosis is not currently available. In the parent grant, significant progress was made toward the identific | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| KANSAS STATE UNIVERSITY | $49,452 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. DESCRIPTION (provided by applicant): Complement is the first line of defense against i | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $101,667 | Grant | Trans-NIH Recovery Act Research Support: In man, tuberculosis disease is highly associated with increased IL-10 production and the use of murine models has confirmed a critical role for IL-10 in disease progression. In this grant we propose to investigate how IL-10 can influence disease progress | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $389,120 | Grant | Trans-NIH Recovery Act Research Support: Calreticulin is an endoplasmic reticulum (ER) chaperone that promotes folding and assembly of glycoproteins, including major histocompatibility complex (MHC) class I molecules. Calreticulin also has the capacity to direct exogenous antigens onto the MHC c | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF ROCHESTER | $484,594 | Grant | Trans-NIH Recovery Act Research Support: The goals of this administrative supplement are (i) to accelerate the progress of the Parent Grant (AI-068056), (ii) to expand our studies of influenza to the new pandemic H1N1 strain of flu and (iii) to stimulate the economy of upstate NY. These goal | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| THE GEORGE WASHINGTON UNIVERSITY | $38,252 | Grant | Trans-NIH Recovery Act Research Support: We received a Summer Student Research Supplement for the Parent grant entitled G?Role of insulin-like signaling in the hookworm infective processG?. This grant provided a summer research experience(s) for 4 undergraduate students in health-related scienti | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $500,000 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the award is to determine whether pharmacological Inositol (1,4,5)Trisphosphate 3-kinase B (ItpkB)-inhibition could provide an avenue towards cost-effectively reducing detrimental T cell function and cytokine storm in swine influenz | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $56,162 | Grant | Trans-NIH Recovery Act Research Support: West Nile virus (WNV), a vector-borne pathogen, has resulted in annual outbreaks of viral encephalitis in North America since 1999. Severe neurological disease (encephalitis or death) has been observed in over 30% of the confirmed WNV cases with a higher | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $7,212 | Grant | Trans-NIH Recovery Act Research Support: Rational and Combinatorial Engineering of AAV Vectors ARRA PURPOSE OF THE SUPPLEMENT All aims of the parent R01 hinge on molecular cloning. The current supplement request is focused on accelerating research goals outlined specifically in these aims. Cur | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $171,650 | Grant | Trans-NIH Recovery Act Research Support: Chronic bacterial infections cause significant morbidity and mortality worldwide. The World Health Organization estimates that 1.7 million people per year die from Mycobacterium tuberculosis infections, which can lie dormant in a healthy host for years. S | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $35,000 | Grant | Trans-NIH Recovery Act Research Support: The main instrument for our studies at NYU is a Zeiss LSM-710 two photon laser scanning microscope with a Mai Tai HP laser. We have been able to image deep in lymph nodes with this system, but have not been able to reproducibly reach splenic white pulp du | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $310,247 | Grant | Trans-NIH Recovery Act Research Support: The parent R01 for this Administrative Supplement is focused on the regulation of the antiapoptotic BCL2 family member MCL1, and the role that MCL1 dysregulation plays in cancer. These studies utilize MCL1 transgenic mice, which exhibit B and T cell expa | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WAKE FOREST UNIVERSITY | $701,622 | Grant | Trans-NIH Recovery Act Research Support: We have demonstrated that epinephrine at concentrations observed during stress induces PKA-dependent phosphorylation of the pro-apoptotic protein BAD and protects prostate cancer cells from apoptosis (JBC2007 in 'appendix'). Furthermore, recent in vivo ex | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $76,338 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this award was to upgrade the current Quantitative Genetic Epidemiology high performance computing (HPC) cluster. The expected outcome was that we would purchase the necessary equipment to upgrade the HPC cluster, and as a result, | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF | $8,475 | Grant | Trans-NIH Recovery Act Research Support: PUBLIC HEALTH RELEVANCE: The HIV/AIDS pandemic affects over 40 million worldwide and over 1.2 million people in North America. HIV primarily replicates in CD4 helper T cells and can induce adhesive infection-promoting intercellular structures between thes | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| UNIVERSITY OF UTAH, THE | $150,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Graft-versus-host disease (GVHD) is the major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. From a genetic perspective, GVHD is a complex phenotypic trait. Susceptibility for GVH | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $109,003 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement is to increase diversity within the national scientific workforce, and within the scientific population of our institution, by supporting the dissertation research of Mr. Mario Giron, a Hispanic-American student in our Ph.D. | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC, THE | $248,499 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funds supplement our existing R01 (AI081615, 02/15/09-01/31/14) in two ways. First, funds were made available for the purchase of a unique device that only recently has become available (2009). This one-of-a-kind machine, the Cryomill (Retsch), w | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $119,910 | Grant | Trans-NIH Recovery Act Research Support: We propose to leverage the patient cohort with metal onmetal hip replacements that is available in Specific Aim #2 of the parent grant. These patients have been followed for up to four years with serial determinations of serum metal concentrations and met | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| THE HOSPITAL FOR SPECIAL SURGERY FUND INC | $7,875 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this supplement was to provide funds for an undergraduate student to validate a spectroscopic measure of bone acid phosphate composition that could be applied during analyses of bone changes in health and disease. The student obtained or s | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $94,948 | Grant | Trans-NIH Recovery Act Research Support: We seek to understand the contribution of extracellular microfibrils to bone physiology and implicitly, to elucidate the pathological underpinning of skeletal manifestations in Marfan syndrome (MFS) and congenital contractural arachnodactyly (CCA). MFS an | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WASHINGTON UNIVERSITY, THE | $107,040 | Grant | Trans-NIH Recovery Act Research Support: Project Summary/AbstractOsteoarthritis will affect 50 million Americans by 2020. The disease process ischaracterized by the aberrant gene expression and the inability of cartilage chondrocytesto repair the extracellular matrix leading to cartilage degener | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF KENTUCKY | $297,000 | Grant | Trans-NIH Recovery Act Research Support: Several studies have established that signaling through mTOR is necessary for growth of adult skeletal muscle. The general objective of the parent grant (AR45617) is to define the molecular mechanisms whereby mechanical events and growth factors mediate t | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $40,800 | Grant | Trans-NIH Recovery Act Research Support: This is an eight week Minority High School Student Internship with the Department of Biochemistry research faculty working on arthritis research. This began with the 1) basic quantitative skills, 2) OSHA required training in laboratory safety, 3) tissue | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $86,192 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): End-stage organ failure or tissue loss is one of the most devastating and costly problems in medicine. The creation of engineered musculoskeletal tissue with functional myotendinous (MTJ) and neuromuscular (NMJ) juncti | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $646,580 | Grant | Trans-NIH Recovery Act Research Support: We have initiated the award and have begun to investigate the role of calcium regulation in hair follicle stem cell biology. With the ARRA funds we have hired an LRSA I level technician who started November 30. No major equipment purchases were made | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $169,214 | Grant | Trans-NIH Recovery Act Research Support: Our overarching goal is to improve patient safety in surgery for spinal stenosis. We hope to achieve this by better informing surgeons' and patients' treatment decisions with individualized data on operative risks. Spinal stenosis is narrowing of the spin | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $170,000 | Grant | Trans-NIH Recovery Act Research Support: Meniscal tears are frequent sources of disability, especially in persons with concomitant knee osteoarthritis (OA). Observational studies suggest that while arthroscopic partial meniscectomy (APM) consistently relieves symptoms and improves functional sta | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $642,833 | Grant | Trans-NIH Recovery Act Research Support: Our preliminary observations, that formed the basis of this application, indicated that the transcription factor FoxO1, through its expression in osteoblasts, inhibits ?-cell proliferation, insulin secretion and insulin sensitivity. The proposed studies w | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WASHINGTON UNIVERSITY, THE | $512,706 | Grant | Trans-NIH Recovery Act Research Support: Chronic itch or pruritus represents a significant clinical problem for which no effective drugs are available. Molecular and cellular mechanisms of chronic pruritus are not well understood and understudied. Recent identification of the first itch-specific | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| NEW YORK UNIVERSITY (INC) | $798,312 | Grant | Trans-NIH Recovery Act Research Support: Keloids are a common form of hypertrophic scar which can be disfiguring. People who suffer from keloids tend to be African-Americans and South Asians and others with dark skin. We propose two aims in this project: 1. To determine the number and function | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $57,583 | Grant | Trans-NIH Recovery Act Research Support: Sepsis is a serious problem in surgical and trauma patients and the leading cause of death in critically ill patients. Many septic patients die of organ failure caused by microvascular dysfunction. Our long term goal is to elucidate the mechanisms by whic | Health and Human Services, Department of / National Institutes of Health | 6/25/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $75,449 | Grant | Trans-NIH Recovery Act Research Support: We hypothesize that: (i) repeat vaccination with melanoma peptides and adjuvant may cause persistence of LNLA and creation of tertiary lymphoid organs at vaccine sites, (ii) extending immunization may result in a secondary set of immune regulatory influen | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $563,495 | Grant | Trans-NIH Recovery Act Research Support: Glioblastoma is the most common and most malignant of human brain tumors. Recent therapeutic advances have improved control of primary tumors, with a significant fraction of tumors responding to initial therapies. Unfortunately, all glioblastomas recur an | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $3,000,000 | Grant | Trans-NIH Recovery Act Research Support: Smoking is the primary cause of lung cancer in US adults, and an important cause of mortality from other conditions. Alcohol use is also an important cause of gastrointestinal cancers. Onset of smoking and alcohol use occurs during adolescence and young a | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $487,829 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Pancreas cancer kills almost 30,000 Americans each year, due both to local progression and to metastatic disease. We have pioneered the concept of maximizing systemic therapy, while incorporating high dose conformal ra | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $169,439 | Grant | Trans-NIH Recovery Act Research Support: Glucocorticoid hormones are very potent inhibitors of physiological DNA synthesis in keratinocytes in vivo. These hormones are also very effective in preventing carcinogen- and tumor promoter-induced skin hyperplasia, inflamination, and mouse skin tumor f | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $137,758 | Grant | Trans-NIH Recovery Act Research Support: The cell biology pathway of autophagy is emerging as both an important mechanism of tumor suppression and an important mechanism of tumor cell survival. An important controversy in the cancer field is whether autophagy should be turned on or turned off i | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF PITTSBURGH THE | $210,612 | Grant | Trans-NIH Recovery Act Research Support: We previously reported a significant association between HHV-8 infection and prostate cancer risk in the Caribbean island of Tobago. We have also demonstrated HHV-8 protein expression in the non-cancerous prostates of U.S. Caucasian men who are HHV-8 ser | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $53,103 | Grant | Trans-NIH Recovery Act Research Support: The long term goal is to identify molecular mechanisms of cancer initiation and progression and hence to improve cancer prognosis and therapy. Smads are transcription factors initially identified as signaling molecules for the transforming growth factor | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $505,848 | Grant | Trans-NIH Recovery Act Research Support: Prostate cancer is the second leading cause of cancer death in man. It is initially responsive to androgen ablative therapy but thereafter patients relapse and develop castration resistant prostate cancer (CRPC). Emerging data suggests that CRPC has under | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF PITTSBURGH THE | $92,319 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this project is to study Benzene-induced leukemogenesis and its prevention. These studies are predicated on the following knowledge: 1) benzene-induced acute myelogenous leukemia (AML) displays MLL gene translocations; 2) benzene leukemo | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $853,883 | Grant | Trans-NIH Recovery Act Research Support: In the next decade, breast cancer screening will likely be some combination of x-ray, ultrasound (US) and/or optical imaging, if this combination can be performed efficiently. Towards this goal, a proof-of-concept multimodality system is proposed in which | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| MAYO CLINIC | $597,475 | Grant | Trans-NIH Recovery Act Research Support: Non-Hodgkin lymphoma (NHL) is now the 5th most frequently diagnosed cancer among both men and women in the US. There is rapidly accumulating evidence for several candidate susceptibility genes in the etiology of NHL, supporting a polygenic model based on | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $344,934 | Grant | Trans-NIH Recovery Act Research Support: The MRN-ATM pathway is primarily involved in sensing, signaling, and repairing DNA double-strand breaks (DSBs). DSBs arise as a consequence of external insults, such as ionizing radiation and are generated in all cycling cells during DNA replication. If u | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $336,597 | Grant | Trans-NIH Recovery Act Research Support: Upper respiratory tract infection (URTI), influenza like illness (ILI) and acute gastrointestinal infection (AGI) are common in the U.S. and are associated with significant morbidity and economic burden. Accumulating evidence indicates that vitamin D may | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $174,409 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this Supplement application is to expand the medical record review component of our study of determinants of mortality after invasive breast cancer in middle- and older-aged women. Medical record reviews are a central part of the data colle | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $163,923 | Grant | Trans-NIH Recovery Act Research Support: There is an urgent need for cost-effective, non-invasive diagnostic techniques for the evaluation of breast lesions. The primary objective of this project is to develop a multiparametric MRI based tissue model to differentiate benign from malignant tissue | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF LOUISVILLE | $119,591 | Grant | Trans-NIH Recovery Act Research Support: The purpose of funding is to test the hypotheses that MIF is critically important for oncogene-induced cyclin D1 expression, Rb inactivation, malignant transformation and de novo tumorigenesis and that MIF participates in cyclin D1 overexpression in sele | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| UNIVERSITY OF MIAMI | $130,249 | Grant | Trans-NIH Recovery Act Research Support: It has recently been appreciated that the aggressive behavior of malignant tumors is related to their extracellular environment. Laminins are the major extra-cellular components of basement membrane that cover the basal surfaces of epithelia and underlie | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | $62,995 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of this proposal is to understand the molecular mechanisms of prostate tumorigenesis due to deregulation of the P13K and PTEN pathway, and to elucidate the connection of P13K and PTEN downstream signaling components to tumor forma | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| OREGON STATE UNIVERSITY | $13,867 | Grant | Trans-NIH Recovery Act Research Support: Cancer is one of the leading causes of death in the US. Chemotherapy remains an important cancer treatment modality. Traditionally, cytotoxic molecules that activate only a single tumor-killing mechanism are used. Combination chemotherapy is now a common | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MEDICAL COLLEGE OF WISCONSIN, INC., THE | $167,200 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to increase the scope of work that will be accomplished to test the hypothesis of the parent project. One of the aims of the parent project is to determine the mechanisms that regulate the release of the endocannabinoids | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| DUKE UNIVERSITY | $11,156 | Grant | Trans-NIH Recovery Act Research Support: The main goal of the summer student supplement is to provide a undergraduate student an opportunity to participate in our preclinical medication treatment project (5R01-DA012768, Cocaine Withdrawal: A Window of Treatment Opportunity). This project seeks | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| NORTHWESTERN UNIVERSITY | $345,189 | Grant | Trans-NIH Recovery Act Research Support: In our original proposal we sought to demonstrate the expression of chemokine receptors by neural progenitor cells in the adult brain, to examine the effect of SDF1/CXCR4 signaling on adult neural progenitor cells in the dentate gyrus (DG), and to investi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF MARYLAND | $55,008 | Grant | Trans-NIH Recovery Act Research Support: Dual-diagnosis in psychiatry refers to the co-existence of drug abuse with a psychiatric condition. This is quite prevalent in schizophrenia, where more than 50% of the patients abuse some type of drug. There is no agreement in the field regarding whether | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| ASTRAEA THERAPEUTICS LLC | $304,447 | Grant | Trans-NIH Recovery Act Research Support: DISCOVERY OF SMALL-MOLECULE ORPHANIN FQ RECEPTOR LIGANDS The nociceptin receptor (NOP, previously known as the opioid receptor-like receptor ORL1) and its endogenous ligand nociceptin or orphanin FQ (N/OFQ) have been shown to play a role in the regulatio | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $373,750 | Grant | Trans-NIH Recovery Act Research Support: Heroin abuse increases the risk of HIV infection and may exacerbate HIV encephalitis (HIVE). Since a large percentage of newly infected HIV patients abuse opiates, this enhancement of disease process has serious medical and social consequences. Little is | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $205,151 | Grant | Trans-NIH Recovery Act Research Support: Long projection axons regenerate poorly through the damaged central nervous system. One key reason is the environment through which they must re grow contains many biochemical signals that trigger signaling pathways which inhibit axon outgrowth. Some of t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $208,400 | Grant | Trans-NIH Recovery Act Research Support: This grant provides support to use phage evolution of a bacteriophage peptide expression library to identify peptides that can a) bind to the tympanic membrane; b) be internalized by tympanic membrane cells and 3) transit from within the tympanic membrane | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $13,905 | Grant | Trans-NIH Recovery Act Research Support: Our studies have revealed that the spiral ganglion is more than just a collection of axon-like elements that act merely as a simple relay into the central nervous system. Instead, we and others have found that this relatively homogeneous group of neurons | Health and Human Services, Department of / National Institutes of Health | 5/28/2009 |
| UNIVERSITY OF UTAH, THE | $358,527 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The sensation of smell enables us to gain valuable information about a plethora of chemicals in our immediate environment, and to respond appropriately. Olfactory receptor neurons (ORNs) are responsible for detection o | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $214,235 | Grant | Trans-NIH Recovery Act Research Support: Studies conducted under this grant are directed at understanding the second messenger-gated ion channels that mediate the transduction of bitter, sweet and umami taste. These tastes are detected by G-protein-coupled taste receptors that initiate a signali | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HASKINS LABORATORIES, INC. | $97,940 | Grant | Trans-NIH Recovery Act Research Support: Administrative Supplement for Equipment | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $89,622 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of my laboratory is to elucidate the mechanisms that control mechanotransduction in hair cells, and the defects in this process that cause deafness. We propose here to use electrophysiological recordings to determine the extent to which | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $327,480 | Grant | Trans-NIH Recovery Act Research Support: The aim of the proposed research is to assess the sensitivity of the latency of the P1 cortical auditory evoked potential as a marker of the development of the central auditory pathways in hearing impaired children who receive intervention through convent | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $320,100 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision Application is being submitted in response to Notice Number (NOT-OD-09-058) and Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications, with respect to the Parent Grant R01DE1613 | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $75,746 | Grant | Trans-NIH Recovery Act Research Support: About 75% of birth defects involve the head, face, and oral tissues. Although orofacial clefts and other craniofacial malformations have clear environmental and genetic causes, insufficient information exists concerning the mechanisms of craniofacial deve | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $8,150 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of this proposed work is to characterize protein-protein interactions involving the enamel extracellular matrix proteins, as well as proteins integral to the plasma membrane of ameloblast cells, and characterize how these interactions r | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| AMERICAN DENTAL ASSOCIATION FOUNDATION | $11,700 | Grant | Trans-NIH Recovery Act Research Support: The goal of this proposal is to establish the minimum concentration of fluoride needed to prevent enamel and root caries. The lack of knowledge about the target concentration of fluoride required in the oral environment to optimize its potential for carie | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $75,392 | Grant | Trans-NIH Recovery Act Research Support: Periodontitis results in loss of tooth-supporting tissues including bone, cementum, and periodontal ligament (PDL), ultimately leading to tooth loss if left untreated. Dental tissue loss represents the second largest patient population next to blood trans | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| AMERICAN DENTAL ASSOCIATION FOUNDATION | $94,450 | Grant | Trans-NIH Recovery Act Research Support: Nano forms of hydroxyapatite, other calcium phosphate compounds, and additional bioactive inorganic materials will be prepared by a newly developed method, employing either a spray drying or a flame pyrolysis technique in such a way that (1) target partic | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $169,033 | Grant | Trans-NIH Recovery Act Research Support: The supplement is to increase the tempo of research that is embodied withing the aims of the parent grant and to replace aging/failing equipment that is integral to the research activities of the grant. This support will enable the development of new and | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $53,495 | Grant | Trans-NIH Recovery Act Research Support: In order to generate the craniofacial skeleton, neural crest progenitors need to adopt one specific fate verses another. It is the long-term goal of my laboratory to determine the molecular mechanisms that regulate cell fate determination of neural crest | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $99,000 | Grant | Trans-NIH Recovery Act Research Support: This award is a supplement for NIH grant 3R0lDE017732 Diabetes-enhanced experiment periodontisis. To be used for the purchase of equipment. | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $383,198 | Grant | Trans-NIH Recovery Act Research Support: Craniosynostosis, the premature fusion of one or more cranial sutures (most commonly those of the calvaria), is a common malformation occurring in 1 out of every 2500 live births, and shows marked variation of cranial phenotypes. Our aims are to study the | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ILLINOIS | $13,502 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this project was employ two student workers and have them contribute to the success of our parent grant related to ameloblastin function. Much of the resilient properties of the periodontium are facilitated by a non-mineralized period | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| WILLIAM MARSH RICE UNIVERSITY | $148,578 | Grant | Trans-NIH Recovery Act Research Support: Recent advances in confocal microscopy have demonstrated the potential of optical imaging to provide molecular images with sub-cellular resolution. In this proposal, we extend our work in high resolution confocal microscopy, based on a much simpler altern | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $251,186 | Grant | Trans-NIH Recovery Act Research Support: CRCNS: Integrated Empirical and Multiscale Modeling of Human Sleep Spindles. The overall goal of the proposed research is to determine how brain events at the biophysical level in the human brain influence the macroscopic recordings outside the skull. The | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $216,613 | Grant | Trans-NIH Recovery Act Research Support: Chronic kidney disease (CKD) is a major global public health problem. Environmental and occupational exposure to lead and cadmium may increase CKD risk independently and in conjunction with established causes, such as diabetes and hypertension. We are inv | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $381,769 | Grant | Trans-NIH Recovery Act Research Support: This supplement accelerates the tempo of research on the three specific aims of the grant by 1) hiring a new research technician who will help work on all three specific aims to move more quickly; 2) hiring a PhD graduate student whose dissertation projec | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| NEW YORK MEDICAL COLLEGE | $403,767 | Grant | Trans-NIH Recovery Act Research Support: The overall objective set forth in the currently funded project was to study the role of the heme oxygenase (HO) system in regulating the corneal inflammatory and repair response. This was based on preliminary studies showing that the HO system is highly | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $18,333 | Grant | Trans-NIH Recovery Act Research Support: Genetic Determinants of Physiological Responses to Fluoride in Bone The supplement will be used to support undergraduate students during their participation in research related to the active parent grant and to accelerate the accomplishment of the goals o | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| VIRGINIA COMMONWEALTH UNIVERSITY | $99,993 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the parent research project is to employ both biochemical and genetic tools to elucidate basic mechanisms that control development stage-specific expression of the vertebrate B-type globin genes. The focus of this project is on the mec | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $29,900 | Grant | Trans-NIH Recovery Act Research Support: This is a continuation of a project, for which the long-term goal is to define T cell effector mechanisms at the level of the small intestinal epithelium, by characterizing the stimulatory and costimulatory signals that drive intestinal intraepithelial ly | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $99,400 | Grant | Trans-NIH Recovery Act Research Support: The description of the work is as defined in the project abstract. We discovered that a single transcription factor, CP2L1, induces the conversion of metanephric mesenchyme into tubules. We discovered this pathway by analyzing genes that were expressed in | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $84,159 | Grant | Trans-NIH Recovery Act Research Support: The award is entitled TGF-beta regulation of intestinal epithelial cells and is a supplement to and existing R01 grant (R01DK059656). This supplemental ARRA funding layers seamlessly onto our laboratory research project investigating the effects of trans | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $150,993 | Grant | Trans-NIH Recovery Act Research Support: Mast-Cell Renin and Local ANG II Formation The primary objective of this extension to the parent proposal is to determine the pro-fibrotic mechanism by which ANG II leads to tubulointerstitial fibrosis. Founded on the tenet proposed in the parent grant th | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $243,750 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of the parent grant is to determine the structural and functional determinants of paracellular permeation in epithelia. We previously developed a model using inducible overexpression of claudin-2 in MDCK I cells to study the properties | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $59,839 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $1,554,684 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $237,000 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 5/01/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $688,201 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $190,035 | Grant | Trans-NIH Recovery Act Research Support: Our long-term goal is to understand how voltage-gated ion channels regulate hair cell excitability, influence sensory processing in the cochlea, and contribute to normal and abnormal auditory function. Calcium-sensitive potassium (BK) channels are widely | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $85,654 | Grant | Trans-NIH Recovery Act Research Support: Among the five senses, hearing is fundamental for acquiring language, communication, and navigating through our environment. An estimated 28 million Americans are deaf or hearing impaired due to genetic factors, sound-induced trauma, aging or presbycusis, | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $149,432 | Grant | Trans-NIH Recovery Act Research Support: The clinical profiles of several developmental disorders, including autism spectrum disorders (ASD), involve varying degrees of comorbid language impairment (LI). Clinical diagnosis of LI, however, does not itself identify the associated underlying neuron | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $64,139 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of this project are to (A) obtain behavioral estimates of tinnitus induced by salicylate or noise exposure, (B) identify the changes in neural activity associated with salicylate or noise-induced tinnitus using MicroPET imaging and elect | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| HOUSE EAR INSTITUTE INC | $45,658 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the supplement is to modernize current research equipment and to enhance energy efficiency in the conduct of the parent project, Development and Adaptive Behavior in Young Children with Hearing Loss. Specifically, support is requested to: 1 | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| MISSOURI SYSTEM, UNIVERSITY OF | $200,001 | Grant | Trans-NIH Recovery Act Research Support: ARRA administrative supplement to R01 DE007389. Regenerative medicine is the process of generating new functional tissues to repair or replace a damaged organ due to disease or damage. Salivary gland tissue regeneration would represent an important advan | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $200,207 | Grant | Trans-NIH Recovery Act Research Support: Nonsyndromic cleft lip and palate (NSCLP) is a common birth defect affecting approximately 4,000 newborns each year in the US and a million worldwide. Multidisciplinary approaches have improved the care of these children but long-term problems persist and | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $21,210 | Grant | Trans-NIH Recovery Act Research Support: Chronic pain, including chronic orofacial pain, remains unsuccessfully treated in a large number of patients. Furthermore, the loss of analgesic efficacy with chronic administration of frontline analgesic drugs, such as morphine, severely limits their use | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $34,389 | Grant | Trans-NIH Recovery Act Research Support: Peripheral neuropathic pain arises from diverse changes in the peripheral and central nervous systems that include a reciprocal interaction between the immune and nervous systems. We find from a microarray expression profile analysis that immunologic gene | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $91,125 | Grant | Trans-NIH Recovery Act Research Support: Evolution of vertebrates has been intimately linked to the advent of the neural crest, a migratory and multipotent cell population that gives rise to many defining characters of vertebrates, including a well-defined head and peripheral ganglia. These mul | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $99,844 | Grant | Trans-NIH Recovery Act Research Support: This project is being supported with funds from the American Recovery and Reinvestment Act, which may involve a reduction in the research aims and scope. If necessary, a revised abstract will be posted soon and this notice removed. DESCRIPTION (provided | Health and Human Services, Department of / National Institutes of Health | 8/21/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $86,440 | Grant | Trans-NIH Recovery Act Research Support: Studies outlined in the revised competing renewal are aimed at understanding the physiologic and therapeutic effect of activating ADO A3 receptors (Rs) in experimental models of colitis. Three specific aim's are addressed in distal colon, the therapeutic | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $48,352 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to determine the functional adaptation and consequences of salt intake on endothelial cell function in the vasculature and the kidney. By defining the signal transduction pathway in endothelial cells, this application will prov | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $104,159 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement to parent grant, DK 48215, intends to accelerate the pace of the animal studies, murine outlet obstruction experiments, which are major components of Aims 2 and 3 of the parent grant. Funds are sought for the purpose of hiri | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE OF | $12,780 | Grant | Trans-NIH Recovery Act Research Support: EryP are the first differentiated cell type to form in the mammalian embryo and play a vital role in oxygen delivery and in generating shear forces necessary for normal vascular development. Despite their abundance and indispensable functions, the develo | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $55,901 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement request for R01 DK052446-11, being submitted in response to NOT-OD-09-056, in compliance with specific guidelines from NIDDK. The title of the parent grant is ?Mechanisms of Regulation of NHE-1? with a current budget | Health and Human Services, Department of / National Institutes of Health | 8/18/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $99,952 | Grant | Trans-NIH Recovery Act Research Support: The cilium has emerged as a critical cellular organelle in the pathology of kidney cystic disease, retin degeneration, hydrocephalus, and left-right asymmetry defects. Now that a large number of proteins have been identified as part of the cilia proteome, | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| UNIVERSITY OF LOUISVILLE | $64,898 | Grant | Trans-NIH Recovery Act Research Support: Summary narrative of ARRA funded project activity/milestones: Research design and methods and data analysis for the summer research supplement: 1. General Research plan: The summer hs student, undergraduate student, and hs science teacher worked with PI | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $100,753 | Grant | Trans-NIH Recovery Act Research Support: Our long-term objective is ,to understand the pathophysiology of autosomal dominant polycystic kidney disease (ADPKD) as a basis for therapy. Autosomal dominant polycystic kidney disease (ADPKD) is the most common lethal monogenic genetic diseases of man, | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF UTAH, THE | $96,273 | Grant | Trans-NIH Recovery Act Research Support: MORBIDITY AND MORTALITY RELATED TO GASTRIC BYPASS SURGERY This four-year renewal application will test the hypothesis that Roux-en-Y gastric bypass (RY-GBP) surgery reduces long-term (5 1/2-year follow-up) morbidity from severe obesity. This will be the f | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $8,200 | Grant | Trans-NIH Recovery Act Research Support: There were two supplements for this award. The first was to support the addition of an undergraduate student during the past summer. The student was hired and worked effectively on this program. The student's work focused on processing brains from develop | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $86,240 | Grant | Trans-NIH Recovery Act Research Support: In our previous work, we suggested that reductions in peritubular capillary (PTC) density compromised blood supply of post-ischemic kidneys, impairing the ability to deliver oxygen to the renal parenchyma and predisposing the fibrotic process (1, 3). Impo | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| WASHINGTON UNIVERSITY, THE | $38,195 | Grant | Trans-NIH Recovery Act Research Support: The long term goal of this project is to understand the molecular mechanisms responsible for altered glucose homeostasis during highly active antiretroviral therapy (HAART). The metabolic changes that occur in association with the use of HIV protease inhi | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| UNIVERSITY OF UTAH, THE | $104,946 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Iron has an essential role in many biological processes, including DMA synthesis/respiration, the tricarboxylic acid cycle, oxygen transport, heme synthesis and photosynthesis. But iron can also be toxic due to its abi | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $99,000 | Grant | Trans-NIH Recovery Act Research Support: Systemic Lupus Erythematosus (SLE) is a heterogeneous disorder characterized by autoimmunity and the development of progressive immune complex renal disease. The pathogenesis of SLE is complex and multi- factorial; substantial clinical and experimental da | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE | $68,947 | Grant | Trans-NIH Recovery Act Research Support: The goal of the original application is to define and characterize the mechanisms responsible for the intrarenal augmentation of angiotensinogen (AGT) expression by angiotensin II (Ang II). The central hypothesis of the original application is that the a | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $37,975 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request is aimed at accelerating the pace and achievement of research in support of the parent grant PDX-1 Regulation of Intestinal Pattern Formation. The overall project is aimed at addressing the hypothesis that PDX-1 is | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF MIAMI | $99,999 | Grant | Trans-NIH Recovery Act Research Support: In a prospective longitudinal study, it is hypothesized that the built environment's walkability will impact the social environment's collective efficacy, and that these environmental variables together will influence physical activity. Controlling for di | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY OF UTAH, THE | $83,618 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. Although the pancreas is a relatively small organ, tucked away in a corner of the dige | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $33,932 | Grant | Trans-NIH Recovery Act Research Support: The present supplement application seeks support for a 2 summers of paid research experience at The Scripps Research Institute for an undergraduate with very high potential for a biomedical research career, a current junior at the University of San Diego. | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $3,280 | Grant | Trans-NIH Recovery Act Research Support: A part-time undergraduate student that is from an underrepresented population in science (African-American) was hired for work on this project. Her efforts focused on immunohistochemical detection of specific proteins in the hypothalamus that may play a r | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| MAINE MEDICAL CENTER | $469,935 | Grant | Trans-NIH Recovery Act Research Support: Defining the progenitor cell niche of the developing kidney (competitive revision). The purpose of this award is to understand pathways that regulate kidney progenitor cells, to ultimately advance the development of cell based therapies for kidney disease | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON UNIVERSITY, THE | $95,910 | Grant | Trans-NIH Recovery Act Research Support: Kidney disease is huge worldwide health problem that is becoming increasingly prevalent. Primary glomerular disease, both acquired and genetic, represents a significant proportion of these cases, due in part to the incidence of diabetic nephropathy. We ar | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| AGRICULTURAL RESEARCH SERVICE | $582,661 | Grant | Trans-NIH Recovery Act Research Support: Project Narrative. A reduced ability of the pancreatic hormone insulin to trigger tissue uptake of blood sugar is an early event in the course of development of type 2 diabetes mellitus (T2DM). Relatively poor fat combustion by fasting muscle is often cor | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| PURDUE UNIVERSITY | $75,341 | Grant | Trans-NIH Recovery Act Research Support: Obesity has become a major public health problem worldwide such .that in developed countries 10-20% of the adult population is obese. As the rates of obesity rise, so do associated health care costs. Few effective approaches for reducing body weight exist | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| UNIVERSITY OF ROCHESTER | $6,608 | Grant | Trans-NIH Recovery Act Research Support: The supplement is to fund an undergraduate student to spend 8 weeks in my laboratory this summer investigating the terminal differentiation of primitive erythroid cells. The summer research experience is designed to encourage undergraduate students to ser | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TOLEDO, THE | $18,240 | Grant | Trans-NIH Recovery Act Research Support: The majority of patients with polycystic kidney disease (PKD) die due to cardiovascular complications such as hypertension, aneurysm, hemorrhage, etc. Our recent data indicate that the cardiovascular hypertension in PKD is associated with functional defe | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF TOLEDO, THE | $92,304 | Grant | Trans-NIH Recovery Act Research Support: Polycystic kidney disease (PKD) is a systemic nephropathy characterized by progressive bilateral renal cyst formation that results in a gradual decline in renal function. Although it is most commonly categorized as a kidney disease, the majority of patien | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $45,664 | Grant | Trans-NIH Recovery Act Research Support: Gastric bypass surgery (GBS) is an exceptionally successful therapy for morbid obesity and type 2 diabetes. GBS patients typically lose 25-35% of total body weight, demonstrate improvements in medical co- morbidities, and sustained weight loss over fiftee | Health and Human Services, Department of / National Institutes of Health | 7/29/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $410,125 | Grant | Trans-NIH Recovery Act Research Support: This award is a competitive supplement for a previously awarded grant. Our initial grant aims at measuring longitudinally (over more than a 20 year period) biomarkers of endothelial cell dysfunction, inflammation and clotting/fibrinolysis factors in the | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $50,259 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement will provide funds for the purchase of an Applied Biosystems 7500 Real-Time PCR system and salary support for a newly hired technician. The parent grant investigates how mutations in chymotrypsinogen C (CTRC) increase the ri | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $93,730 | Grant | Trans-NIH Recovery Act Research Support: The goal of the supplement fund is to develop a Fourier domain optical coherence tomography (FD-OCT) system that will achieve high resolution and high speed simultaneously. The proposed research will accelerate the translation of this technology to clini | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MIAMI | $152,908 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request seeks to accelerate software development for a system that provides fully-automated processing and analysis of volumetric metabolite images. This aim directly supports all Specific Aims of the parent grant, while add | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $254,544 | Grant | Trans-NIH Recovery Act Research Support: The overall scope of the parent project (5R01 EB 001659) is to develop and evaluate advanced patient-monitoring and clinical decision-support concepts that will improve the efficiency, accuracy, and timeliness of decision-making in critical care. In pursu | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF UTAH, THE | $175,775 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): A biomimetic strategy is proposed to develop a new class of adhesives for orthopedic medicine, particularly joint fractures with multiple bone fragments. The adhesive is modeled after a natural underwater adhesive secr | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CINCINNATI | $98,490 | Grant | Trans-NIH Recovery Act Research Support: This competing renewal application aims at investigating the hypothesis that exposure of human melanocytes to ultraviolet radiation (UV) and/or the physiological agonist 1-melanocyte stimulating hormone (1-MSH) or antagonist agouti signaling protein (ASIP | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| COLORADO STATE UNIVERSITY | $34,274 | Grant | Trans-NIH Recovery Act Research Support: Chronic intoxication with manganese (Mn) is the cause of a degenerative movement disorder, termed manganism, with clinical features that resemble Parkinson`s disease. Recent findings suggest that injury to this region of the brain involves perturbation of | Health and Human Services, Department of / National Institutes of Health | 7/11/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $52,308 | Grant | Trans-NIH Recovery Act Research Support: The proposed supplement to the ongoing study of chilhood asthma is designed to accelerate the rate of recruitment of study subjects. Parents will be administered a standardized asthma questionnaire (ISAAC) to determine presence and frequency of asthma sy | Health and Human Services, Department of / National Institutes of Health | 9/05/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $67,208 | Grant | Trans-NIH Recovery Act Research Support: The ARRA funded a Research Supplement to Promote Diversity in Health-Related Research that was used to provide employment for a recent college graduate. She conducted research on the interaction of genetic and environmental risk factors in autism. Manus | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| NEW YORK UNIVERSITY | $179,556 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides support for one postdoctoral scientist to accelerate the pace of the research. The neural competition underlying perceptual alternations during rivalry is believed to be closely related to the strabismic suppression. Hence, the pr | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| THE VANDERBILT UNIVERSITY | $173,888 | Grant | Trans-NIH Recovery Act Research Support: This supplement request is to support the hiring of an outstanding postdoctoral research associate who will take on a central role in carrying out fMRI studies of motion perception, Aim 2 of this R01 project. The PI has lab members actively working on stu | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SMITH-KETTLEWELL EYE RESEARCH INSTITUTE, THE | $92,207 | Grant | Trans-NIH Recovery Act Research Support: The objective of the parent grant is to develop an eye movement model that can predict task-dependent fixation patterns in human observers, and to apply this same model to study eye movement behavior in patients with macular degeneration and other causes | Health and Human Services, Department of / National Institutes of Health | 8/19/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $151,276 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to elucidate the mechanistic basis of ocular morphogenesis in vertebrates. During ocular morphogenesis, the optic primordia undergo a complex series of morphogenetic movements that ultimately result in a bilayered opt | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CREIGHTON UNIVERSITY | $29,825 | Grant | Trans-NIH Recovery Act Research Support: This supplement will provide summer funding for undergraduates to participate in research. Students will assist in the animal experiments and cell culture exeriments as a part of the parent grant. This award will accelerate the successful completion of th | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $270,363 | Grant | Trans-NIH Recovery Act Research Support: Adverse human health effects due to occupational and environmental exposure to nanomaterials are a major concern and a potential threat to their successful commercialization and biomedical applications. Realization of their commercial potential will requi | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $412,945 | Grant | Trans-NIH Recovery Act Research Support: The developing central nervous system is particularly vulnerable to environmental toxicants such as heavy metals. While lead (Pb) poisoning has been extensively studied, the neurotoxicities and dose-effect relationships associated with other heavy metals, | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| CEDARS-SINAI MEDICAL CENTER | $641,218 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to identify susceptibility genes involved in the pathogenesis of keratoconus (KC). We will achieve our goal by: 1) refining criteria for the early detection of KC using videokeratography and wavefront Zernike variables; 2) com | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF NEW MEXICO | $274,999 | Grant | Trans-NIH Recovery Act Research Support: Retinal neovascularization is the leading cause of blindness in the United States among working-age adults (diabetic retinopathy) and infants (retinopathy of prematurity). An important event of the angiogenesis cascade is the breakdown of the capillary ba | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $74,312 | Grant | Trans-NIH Recovery Act Research Support: The goal of this supplemental award is to accelerate our progress on understanding how the brain takes incoming visual information and constructs a neuronal representation (pattern of brain activity) used to recognize and remember objects, even though eac | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $103,259 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to increase understanding of retinal iron homeostasis through the study of transgenic and knockout mice. These mice are expected to develop retinal degeneration with features of age related macular degeneration, serving both as | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $193,887 | Grant | Trans-NIH Recovery Act Research Support: Successful development of a functional eye requires not only cell-differentiation programs that specify various retina cell types, but also size-control mechanisms that determine the number of cells in the retina. The long-term scientific goal of my labor | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| GEORGETOWN UNIVERSITY (THE) | $8,903 | Grant | Trans-NIH Recovery Act Research Support: By studying the brain in live and behaving subjects, we obtain fundamental insight into the neural basis of natural behaviors. Such basic biology research is essential as the fundamental underpinning for understanding brain function when compromised by di | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $58,458 | Grant | Trans-NIH Recovery Act Research Support: Funds from this administrative supplement are being used to purchase the CFX96 Real-Time PCR Detection System (Bio-Rad Laboratories, Hercules, CA) including a computer, software, and essential SYBR green fluorescence reagents, as proposed in the supplemen | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF WASHINGTON | $266,093 | Grant | Trans-NIH Recovery Act Research Support: This supplement will accelerate progress on all three Aims of my funded NEI grant, Role of cerebellar parallel fibers in saccade accuracy, R01 EY018585, Farrel R Robinson, P.I. Aims 1 and 2 include quantitative analysis of voluntary rapid eye movements, | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $318,487 | Grant | Trans-NIH Recovery Act Research Support: Driving of the personal vehicle is the primary and preferred mode of travel for older adults in the U.S. More than fulfilling the critically important getting around or mobility function, driving in older adults profoundly impacts health status and thus h | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF ROCHESTER | $168,588 | Grant | Trans-NIH Recovery Act Research Support: One major group of general aims of our research is to identify N-terminal acetyltransferases (NATs), their subunit composition, their substrates, their functions and their interactions. In general, much of our research is hampered by the lack of properly | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $143,250 | Grant | Trans-NIH Recovery Act Research Support: The long-term goals are to understand the biochemical mechanisms, physiological regulation, and biological roles of initiation factors that recruit mRNA to the ribosome, a process that determines rate of protein synthesis, spectrum of mRNAs translated, an | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| WILLIAM MARSH RICE UNIVERSITY | $46,118 | Grant | Trans-NIH Recovery Act Research Support: Biological systems universally employ cascades of binding/catalytic events to transmit information regarding environmental and physiological states. This communication network requires that protein function be altered by allosteric mechanisms. The dearth | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MAYO CLINIC | $157,070 | Grant | Trans-NIH Recovery Act Research Support: Sphingolipids (SLs) play roles in a wide variety of cell functions, including cell-cell interactions, cell growth and differentiation, and signal transduction. SLs can interact with cholesterol to form membrane microdomains, and data from many studies sug | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $340,780 | Grant | Trans-NIH Recovery Act Research Support: We will use mass spectrometry to discover proteins or protein modifications on the cell surface that are selective for dividing or dying cells. These will provide biomarkers for understanding how anti-mitotic drugs work or fail in cancer therapy, as well | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $256,994 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): During the previous funding period we discovered the pathogenic role of two proteins in neurological disease. By positional cloning the mouse neurological mutant pale tremor, with neurodegeneration in peripheral gangli | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $109,647 | Grant | Trans-NIH Recovery Act Research Support: The dynamics which contribute to enzyme catalysis are best understood by defining two classes of motion G?? preorganization and reorganziation. Preorganization refers to how enzymes select the proper conformers needed to facilitate the catalytic chemical | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $431,200 | Grant | Trans-NIH Recovery Act Research Support: Our laboratory has been funded for ~30 years by RO1-GM26108 to investigate the mechanisms of replication control in mammalian chromosomes. We identified the first origin of replication, which lies downstream from the DHFR gene in Chinese hamster cells. | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $149,538 | Grant | Trans-NIH Recovery Act Research Support: The presence of organelles, areas of biochemical specialization, separated from one another other by membranes, characterize eukaryotic cells. Such cellular organization necessitates elaborate mechanisms to effectively deliver the correct macromolecules | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| CORNELL UNIVERSITY, INC | $49,950 | Grant | Trans-NIH Recovery Act Research Support: Our research is focused on important aspects of respiratory chain assembly in mitochondria, using yeast as a model organism. We are seeking to understand the regulation of mitochondrial gene expression by proteins encoded in the nucleus that are required | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| EMORY UNIVERSITY | $89,745 | Grant | Trans-NIH Recovery Act Research Support: This funding has purchased a state of the art rapid scan stopped flow spectrometer for use in biochemical research on the structure and function of the human enzymes Monoamine Oxidase A and Monoamine Oxidase B. These enzyme are know to be elevated in the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $294,438 | Grant | Trans-NIH Recovery Act Research Support: The project funded by GM32335 is directed at the study of recombinational DNA repair in bacteria. Specifically, the work focuses on a better understanding of the RecA protein and its regulation. The biochemistry makes use of literally scores of different | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $410,652 | Grant | Trans-NIH Recovery Act Research Support: To fully understand the cell cycle regulatory network as an integrated system that takes into account the 3D organization of the cell, work on grant R01 GM032506 is focused on how and why regulatory and structural proteins are localized to specific cell | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $254,258 | Grant | Trans-NIH Recovery Act Research Support: The supplement has enable the group to retain a highly productive and experienced Research Specialist who otherwise would have her position. Additionally, the extended research proposed here is likely to add substantially to our understanding of subcellul | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CONNECTICUT | $277,650 | Grant | Trans-NIH Recovery Act Research Support: The correct transport of proteins must occur across the membranes of all prokaryotic and eukaryotic cells. The targeting and transport of these proteins requires several proteinaceous components that comprise the cellular transport pathway and a signal pe | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $92,499 | Grant | Trans-NIH Recovery Act Research Support: This application addresses the pathophysiology of sepsis and its complications potentially leading to multiple organ failure and death. This supplement aims to continue the following research: (1) Accelerate the pace of the characterization of organ-speci | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $41,738 | Grant | Trans-NIH Recovery Act Research Support: This supplement request is to continue our ongoing work on the cyt bc1, by pursuing during the next two years the following specific aims, which are the natural extensions of the current work. We propose: 1 To assess the critical role of the Y302 positi | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TENNESSEE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement award provides funding ($100,000) to purchase a new research microscope to facilitate and increase the rate of work on our studies of chromosome pairing in Drosophila. The work was previously approved under NIH grant number | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF IOWA, THE | $31,268 | Grant | Trans-NIH Recovery Act Research Support: Multidrug resistance is an important clinical impediment in the use of chemotherapies of all types. We are using the yeast Saccharomyces cerevisiae as a model eukaryotic system that has a well described set of multidrug resistance loci called pleiotropic | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $84,074 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Myosin II plays fundamental roles in cytokinesis, cell migration, and cell shape changes during development. In all these settings, it is well established that dynamic localized assembly of myosin into the cytoskeleton | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $248,693 | Grant | Trans-NIH Recovery Act Research Support: Integrin-dependent adhesion and signaling are required for cell motility, survival, and responsiveness to mechanical cues. Cells of the respiratory, cardiovascular, musculoskeletal, and urogenital systems are exposed to physical tension as part of their n | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND | $47,019 | Grant | Trans-NIH Recovery Act Research Support: DNA and RNA exhibit an amazing degree of conformational polymorphism that is essential for their wide variety of biological functions, including replication and gene regulation. The importance of this polymorphism in the biological functions of oligonucle | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $75,404 | Grant | Trans-NIH Recovery Act Research Support: Accurate chromosome segregation is essential for the propagation of species and the viability of cells, and is driven by a complex microtubule-based structure called the spindle. Spindle organization and chromosome movement are driven by the concerted act | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $234,053 | Grant | Trans-NIH Recovery Act Research Support: This is a supplemental request to the parent grant, Biochemistry and Regulation of Cadherin Activity, that will not add to the scope or specific aims. Rather it will provide funds for the retention of a key person who was listed without salary on the orig | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $90,817 | Grant | Trans-NIH Recovery Act Research Support: Post-transcriptional regulatory mechanisms play a role in gene expression in probably all organisms. TRAP of Bacillus subtilis regulates tryptophan biosynthesis and transport by transcription attenuation and translational control mechanisms. When activate | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| CORNELL UNIVERSITY, INC | $170,227 | Grant | Trans-NIH Recovery Act Research Support: We propose to determine the first genome-wide estimate of mutation rates in cells that undergo meiosis. These studies will address whether cells in meiosis sustain higher rates of mutagenesis relative to mitotic cells and whether homologous recombination | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| EAST TENNESSEE STATE UNIVERSITY | $114,990 | Grant | Trans-NIH Recovery Act Research Support: The critically ill patient frequently develops a complex disease spectrum that may include adult respiratory distress syndrome (ARDS), systemic inflammatory response syndrome (SIRS), sepsis syndrome and/or septic shock. At present, we do not understand th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $253,744 | Grant | Trans-NIH Recovery Act Research Support: We hope to increase our understanding of how the heart responds to reduced oxygen in terms of gap junction protein regulation. Specifically, our goals are to characterize changes in the gap junction protein connexin43 phosphorylation and function in heart | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $186,745 | Grant | Trans-NIH Recovery Act Research Support: Detection of folding defects in mutant CFTR by ERQC: The purpose of this ARRA award is to develop an assay to be used to identify compounds that can be used as drugs to correct defects in CFTR that cause Cystic Fibrosis. Funds in the award are aimed at | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $115,614 | Grant | Trans-NIH Recovery Act Research Support: Controlling transcription factor activity by regulating nuclear and cytoplasmic localization is an important and evolutionarily conserved mechanism. Members of the nuclear receptor (NR) super-family of ligand-regulated transcription factors undergo cycles | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $203,570 | Grant | Trans-NIH Recovery Act Research Support: The principal activity under this Administrative Supplement is to prepare additional TGF-? and TGF-? receptor variants, so as to increase our understanding of the similarities and differences with which the three TGF-? isoforms bind and assemble their rec | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $132,688 | Grant | Trans-NIH Recovery Act Research Support: In the female mammal, one of two X-chromosomes is inactivated to ensure that males and females have equal X-chromosome dosage. X-chromosome inactivation (XCI) can take place randomly or in an imprinted manner on the paternal X (XP). In the mouse, random X | Health and Human Services, Department of / National Institutes of Health | 9/10/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $77,527 | Grant | Trans-NIH Recovery Act Research Support: Our lab is interested in how the dynamic microtubule (MT) cytoskeleton contributes to the assembly of the mitotic spindle and to chromosome segregation. This is a fundamental problem in cancer cell biology as defects in chromosome segregation are associat | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $108,624 | Grant | Trans-NIH Recovery Act Research Support: The scope of this proposal is to study the function of mammalian lysosomal neuraminidase (NEU1) in normal cell metabolism, and the consequences of its loss in human diseases. NEU1 belongs to the ubiquitous superfamily of sialidases. Mammalian neuraminidas | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $134,681 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this administrative supplement is to develop the genetic tools necessary to determine the mechanism by which PPS (CG6525) contributes to Sex-lethal splicing autoregulation. These studies fall under the auspices of Aim 1 of the parent grant. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $204,740 | Grant | Trans-NIH Recovery Act Research Support: The first aim of the parent project is to study the molecular mechanisms underlying the antagonistic interactions between AP2 and AG. It was already known that AP2 represses the transcription of AG in the outer two whorls, thus limiting the activity of AG | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MARYLAND | $309,971 | Grant | Trans-NIH Recovery Act Research Support: Examine an RNA conformational switch in the related 3 regions of a satellite RNA (satC) of Turnip crinkle virus. This funding provides for a Postdoc and a summer support for a minority undergraduate student and a high school biology teacher to explore re | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| UNIVERSITY OF SOUTH ALABAMA | $58,723 | Grant | Trans-NIH Recovery Act Research Support: THE DIFFERENITIATION OF B-LYMPHOCYTES INTO ANTIBODY-SECRETING PLASMA CELLS IS MARKED BY EXPANSION OF THE ENDOPLASMIC RETICULUM (ER). THE SITE OF ANTIBODY SYNTHESIS AND ASSEMBLY. THE PROCESS OF ER EXPANSION IS CRITICAL FOR ANTIBODY-MEDIATED IMMUNITY. THIS | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| THE VANDERBILT UNIVERSITY | $131,568 | Grant | Trans-NIH Recovery Act Research Support: S100 proteins are a group of calcium sensor proteins found only in humans and other vertebrate animals. They are members of the EF-hand family of calcium binding proteins, uniquely distinguished by their ability to be secreted into the extracellular space | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ROCHESTER | $78,724 | Grant | Trans-NIH Recovery Act Research Support: Approximately 40% of the total energy production of E. coli is consumed to synthesize the large number of ribosomal components: 3 RNAs (comprised of more than 400 nucleotides) and greater than 50 proteins. This observation and the direct correlation betwe | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $433,276 | Grant | Trans-NIH Recovery Act Research Support: X-ray crystallography using synchotron radiation is the dominant source of structural information of biological molecules and their assemblies: The scope and specific aims of this request are: 1) complete the design of the production automounter based | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $111,932 | Grant | Trans-NIH Recovery Act Research Support: The assembly of eukaryotic DNA into chromatin structure is essential for the faithful propagation of both the genetic and epigenetic information contained in our chromosomes. In addition, chromatin structure plays an intimate role in the proper progressio | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| BAYLOR COLLEGE OF MEDICINE | $129,006 | Grant | Trans-NIH Recovery Act Research Support: Discover the switch permitting non-homologous recombination using expression analysis, proteome analysis, cell sorting and biofilm. ABSTRACT - In this extension of our previous Aim 2, Identification of new proteins and role(s) of the starvation/general s | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $91,650 | Grant | Trans-NIH Recovery Act Research Support: The goal of the parent project is to achieve a greater structural and functional understanding of the macromolecular complexes formed by the 5'-untranslated region (5' - UTR) of the HIV-1 genome and the nucleocapsid (NC) domain of the Gag polyprotein. Th | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $130,529 | Grant | Trans-NIH Recovery Act Research Support: A thorough description of the GO-like resting states of eukaryotic cells is essential for a complete understanding of the mechanisms controlling cell proliferation. Towards this end, we have been studying how the Ras/cAMP-dependent protein kinase (PKA) si | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF ROCHESTER | $104,464 | Grant | Trans-NIH Recovery Act Research Support: The iron-sulfur enzyme nitrogenase converts atmospheric nitrogen into ammonia, but the role of iron in the reaction is not understood. This project studies simple iron compounds in an effort to demonstrate the fundamental reactions taking place in the enz | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| GEORGIA TECH RESEARCH CORPORATION | $107,834 | Grant | Trans-NIH Recovery Act Research Support: Integrin-mediated cell adhesion to extracellular matrices regulates the organization, maintenance and repair of numerous tissues, and abnormalities in adhesive interactions are often associated with pathological states. The adhesive process comprises inte | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $269,927 | Grant | Trans-NIH Recovery Act Research Support: We seek an Administrative Supplement for collaborative science to supplement ongoing NIH grant GM065997. The proposed supplement will allow us to investigate in greater detail the objectives of Aim 1 of the parent grant. In particular, we propose to colla | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RHODE ISLAND HOSPITAL | $247,080 | Grant | Trans-NIH Recovery Act Research Support: Inflammation is an essential response to injury or infection as it prevents infections from becoming widespread and begins the process of healing. White blood cells (leukocytes) circulate continuously in the bloodstream but in response to a local site of | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF WASHINGTON | $220,497 | Grant | Trans-NIH Recovery Act Research Support: This application requests a two-year administrative supplemental support to grant 5R01GM066233. The long term goal of the parent grant is to elucidate the molecular and cellular mechanisms of organic cation transport at the CNS barriers. The central hyp | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $687,824 | Grant | Trans-NIH Recovery Act Research Support: Methylamine dehydrogenase (MADH), a metabolic enzyme found in methylotrophic/autotrophic bacteria, contains a quinone cofactor, tryptophan tryptophylquinone (TTQ), derived from the post-translational modification of two Trp residues in the protein. The ma | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |