Listing all stimulus spending by amount, in descending order. Return to National Institutes of Health page
Amount refers to both the amount of stimulus funding going toward the project and the face value of the loan.
| Recipient | Amount | Type | Description | Federal Dept./Agency | Date |
|---|---|---|---|---|---|
| NEW YORK UNIVERSITY | $234,230 | Grant | Trans-NIH Recovery Act Research Support: This supplement increases project support, both for personnel and other costs, to accelerate the pace of the research. As a unique aspect of developing cognitive competence with a well-defined neurobiological basis, Executive function (EF) has been shown | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND | $175,652 | Grant | Trans-NIH Recovery Act Research Support: National Assessment of Educational Progress statistics show that 68% of young adolescents in Grade 8 were at or below Basic, and more than 50% have very low motivation for school reading. To study this crisis of low literacy in middle school students, we | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $27,640 | Grant | Trans-NIH Recovery Act Research Support: Supplemental request for funds to purchase equipment (an environmental chamber) and to pay for user fees on the new state-of-the-art two-photon microscope in the Johns Hopkins University School of Medicine?s core imaging facility. These purchases will gre | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $222,039 | Grant | Trans-NIH Recovery Act Research Support: The aim overall of this application is to enhance capacity to perform early developmental interventions and neurodevelopmental assessments in order to conduct collaborative research that will evaluate a program of early developmental intervention to reduc | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CHICAGO, THE | $45,476 | Grant | Trans-NIH Recovery Act Research Support: The goal of the research is to elucidate Ca2+ signaling mechanisms underlying the pubertal increase in GnRH secretion. The requested supplement will pay for equipment and personnel to accelerate the tempo of the research and allow for retention and incre | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $326,024 | Grant | Trans-NIH Recovery Act Research Support: The microbes that inhabit human bodies outnumber the human cells by an order of magnitude, and impact many aspects of health and disease including obesity, vaginosis, and Crohn's disease. Understanding this endogenous microbiota is emerging as a key exten | Health and Human Services, Department of / National Institutes of Health | 8/06/2009 |
| UNIVERSITY OF NOTRE DAME DU LAC | $34,800 | Grant | Trans-NIH Recovery Act Research Support: The overall goals of this research program during a more than a 30-year period of continual funding are to define structure-function relationships of vitamin K-dependent coagulation proteins, both in vitro and in vivo, with specific attention paid to inte | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $292,784 | Grant | Trans-NIH Recovery Act Research Support: The parent grant of this supplement focuses on identifying the molecular pathways that mediate the response of the heart to heart attack. We have previously shown that two highly similar enzymes present in the heart called delta and epsilon protein kinase | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| WAYNE STATE UNIVERSITY (INC) | $17,705 | Grant | Trans-NIH Recovery Act Research Support: The research area is focused on the mechanisms mediating the altered cardiovascular responses to dynamic exercise in subjects with congestive heart failure. Specifically, we will determine the role of coronary vasoconstriction in mediating the inability | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| GEORGETOWN UNIVERSITY (THE) | $19,034 | Grant | Trans-NIH Recovery Act Research Support: In the rat,two distinct angiotensin type la receptor (AT]aR) mRNAs are synthesized from a single ATlaR gene. These transcripts are comprised of exons 1 and 3 (El,3) and exons 1, 2 and 3 (El,2,3). These 2 transcripts code for identical receptor proteins an | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| KENNESAW STATE UNIVERSITY | $89,487 | Grant | Trans-NIH Recovery Act Research Support: Funds will be used to purchase a GE Healthcare AKTA Purifier 100 fast protein liquid chromatography system with necessary add-on kits to allow automated, unattended protein purification on a scale necessary to conduct the proposed experiments, thus bypass | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF NEW ENGLAND | $222,798 | Grant | Trans-NIH Recovery Act Research Support: To increase the progress on the parent grant Ecdysone modulation of sexual behavior in Drosophila melanogaster. Funds have allowed the creation of a new full time research position (post doctoral associate) and a part time teaching position to relieve th | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| REED INSTITUTE, THE | $74,222 | Grant | Trans-NIH Recovery Act Research Support: This ARRA grant provides funds to purchase a fluorescent microscope to be used by student and faculty researchers at Reed College for the purpose of localizing gene expression in the brain. It also provides funds to construct a database of gene expression | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SANTA CLARA COLLEGE | $38,548 | Grant | Trans-NIH Recovery Act Research Support: This supplement was requested to accelerate the progress toward selection of novel aptamers for peptide variants of vascular endothelial growth factor (VEGF). In particular, we aimed to develop aptamers that specifically bind peptides with unique glycosy | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| THE TRUSTEES OF MOUNT HOLYOKE COLLEGE | $48,250 | Grant | Trans-NIH Recovery Act Research Support: DNA damage, repair (or the lack of repair), and mutation are often critical events in the processes of aging and carcinogenesis. Thus we must understand how damage to the DNA is detected and repaired in order to meaningfully assess the long-term effects | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MIAMI UNIVERSITY | $30,000 | Grant | Trans-NIH Recovery Act Research Support: Project Summary: The Na,K-ATPase alpha4 isoform has been found only in the membrane of male germ cells of rats and is most abundant in mature sperm. Specific pharmacological inhibition of this Na,K-ATPase isoform using the cardiac glycoside ouabain has be | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| SAINT LOUIS UNIVERSITY | $117,830 | Grant | Trans-NIH Recovery Act Research Support: This request for a research employment opportunity for a postdoctoral student (fellow) will aid investigation of lower extremity movement impairments in individuals with chronic patellofemoral pain. The proposal would help achieve the goals of the ARRA by | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NEVADA SYSTEM OF HIGHER EDUCATION | $26,640 | Grant | Trans-NIH Recovery Act Research Support: Specific Aims for the Supplement: Supplemental funding to the parent R15 grant will enable us to pursue the following two specific aims: Specific Aim 1: Characterize the effects of BFA and GABA on the release of IL-6 from, and the intracellular accum | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $111,749 | Grant | Trans-NIH Recovery Act Research Support: This ARRA Administrative Supplement to provides a significant portion of support for a research assistant. Adding a new research assistant will accelerate the tempo of the research who will further develop genotyping assays for identified functional allel | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SAINT LOUIS UNIVERSITY | $33,126 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this grant application is to establish highly efficient HCV 1a replication and growth in immortalized human hepatocytes. For this, we plan to generate a high titer HCV 1a by characterizing virus growth in IHH following different approa | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $99,660 | Grant | Trans-NIH Recovery Act Research Support: Brucella melitensis is a human and animal bacterial pathogen of global significance. Although bacterial factors mediating the host-pathogen interaction have been revealed, host factors that are important for B. melitensis entry and replication in mammalia | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $174,056 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): A training program is proposed to increase the participation of biostatisticians in key application areas of the biosciences. Students in this program will be educated not only in the powerful methods of modern statist | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $174,056 | Grant | Trans-NIH Recovery Act Research Support: ARRA funds will enable the support of two new graduate students in the Chemistry/Biology interface training program (CBiTP) at MIT. The CBiTP brings together approximately 30 faculty members from the Departments of Chemistry, Biology, and Biological Engin | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $104,134 | Grant | Trans-NIH Recovery Act Research Support: Despite scientific advances, there is an acute need for sophisticated, socially-relevant, multidisciplinary collaborative research to build our capacity to promote all youngsters' mental health, to prevent the problems that jeopardize their social and aca | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| SAN JOSE STATE UNIVERSITY FOUNDATION INC | $63,266 | Grant | Trans-NIH Recovery Act Research Support: We are seeking to continue to expand the numbers of underrepresented minority students graduating and seeking careers in the biomedical sciences from the tenth largest producer of minority undergraduate degrees in the Nation. Over the previous four years | Health and Human Services, Department of / National Institutes of Health | 8/07/2009 |
| UNIVERSITY OF NEW MEXICO | $272,031 | Grant | Trans-NIH Recovery Act Research Support: The aims of this supplemental application are threefold; each aim supports the current MARC Program in different ways. Aim 1: Our top priority is to add some much-needed laboratory space to our communal Molecular Biology Facility. This facility is used b | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| WINSTON-SALEM STATE UNIVERSITY FOUNDATION, INCORPORATED | $309,231 | Grant | Trans-NIH Recovery Act Research Support: WSSU seeks to establish a Minority Access to Research Careers Student Training in Academic Research (MARC U*STAR) program to promote advancement of minorities who pursue advanced research careers in biomedical science. WSSU proposes to accomplish the foll | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $423,500 | Grant | Trans-NIH Recovery Act Research Support: Ocular toxoplasmosis is an inflammatory eye disease caused by infection with the parasite, Toxoplasma gondii. In the US alone, this condition is estimated to affect over 1.25 million individuals. In otherwise healthy adults, who constitute the largest gro | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF UTAH, THE | $599,559 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): A prominent cause of deafness is loss of hair cells due to age, noise or antibiotic treatments. In contrast to mammalian hair cells, fish, bird and amphibian hair cells are constantly turning over and regenerate follow | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $992,972 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational Science and specific Challenge Topic, 15-DK-103: 'Translate discovery of new molecules/pathways in pathogenesis of NIDDK diseases in potential therapies.' We have assembled a team of exper | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF WASHINGTON | $977,615 | Grant | Trans-NIH Recovery Act Research Support: Lithotripsy still accounts for more than half of all treatments for kidney stone disease, it is gradually being replaced by minimally-invasive procedures, such as ureteroscopy and percutaneous nephrolithotomy. These more invasive procedures are likely the | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WASHINGTON UNIVERSITY, THE | $904,845 | Grant | Trans-NIH Recovery Act Research Support: The urinary tract (UT) is a common site of infection in humans, with an estimated 8 million outpatient visits in the U.S. and an estimated cost exceeding $2.5 billion annually. The most frequent sufferers are women, with a 50% lifetime chance of developin | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $723,920 | Grant | Trans-NIH Recovery Act Research Support: 1R21HL092814-01 Biomimetic Approach to the Fabrication of Red Blood Cell Mimics for Therapeutic Applications We propose to take a biomimetic approach to the design of long circulating particles which resemble red blood cells (RBC) using a nano-molding t | Health and Human Services, Department of / National Institutes of Health | 5/18/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $402,500 | Grant | Trans-NIH Recovery Act Research Support: A computer simulation of lung disease will be created to be a tool for virtual experimentation. It will incorporate what is known about the complex biological processes involved in lung injury and repair and apply it to the analysis of acute and chronic, | Health and Human Services, Department of / National Institutes of Health | 5/13/2009 |
| WASHINGTON UNIVERSITY, THE | $303,463 | Grant | Trans-NIH Recovery Act Research Support: Genetic dissection of hypertension (HTN) and co-morbidities, carried out largely through traditional linkage analysis, has mostly been unsuccessful to date in identifying specific genetic variants. Motivated by existing evidence that some of the genetic e | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| WAKE FOREST UNIVERSITY | $362,622 | Grant | Trans-NIH Recovery Act Research Support: Recommendations for more effective long-term weight loss strategies may need to consider the role of gender differences. If, as shown in female vs. male animal models, negative energy balance resulting in weight loss results in greater compensatory reduct | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $418,590 | Grant | Trans-NIH Recovery Act Research Support: This application's long-term goal is to elucidate the genetic regulation of the ' fibrinogen isoform as a foundation for understanding its role in cardiovascular disease. The specific hypothesis behind the proposed research is that elevated ?' fibrinogen | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| NEW YORK BLOOD CENTER, INC., THE | $442,175 | Grant | Trans-NIH Recovery Act Research Support: Overall purpose: Identification of molecular signatures of antibody responders in transfused recipients through analysis of phenotypic and functional characteristics of regulatory T cells and effector T-cells during red cell transfusions. | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $409,326 | Grant | Trans-NIH Recovery Act Research Support: Many clinical applications, including reporting tools and electronic health records, subscribe to a paradigm of forms-based interfaces, where the software prompts the user with a sequence of forms for data entry. In this paradigm. the user interface is th | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $424,876 | Grant | Trans-NIH Recovery Act Research Support: This revised proposal, Developing Locally-Tailored Prevention Programming for Children of Incarcerated Mothers, uses a community-based participatory research (CBPR) approach to tailor and deliver an existing selective prevention program (Kumpfer's Strengt | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF ILLINOIS | $414,663 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this grant is to develop technology to allow for the control of the neurochemical microenvironment in brain slice physiology experiments.The brain slice preparation has provided amazing access to details of cellular and circuit level brain | Health and Human Services, Department of / National Institutes of Health | 5/07/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $309,000 | Grant | Trans-NIH Recovery Act Research Support: The human DISC1 gene has been proposed to be one of the most compelling susceptibility genes for schizophrenia, a chronic, severe mental disorder imposing a high financial burden on the quality of life of the patients, their families and communities. Rece | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $412,500 | Grant | Trans-NIH Recovery Act Research Support: A major contribution of this research is that the project will generate rich and in-depth data/evidence from a culturally diverse sample of urban-dwelling individuals with mental illness based on their lived experiences and perspectives to better conceptu | Health and Human Services, Department of / National Institutes of Health | 4/30/2009 |
| FOX CHASE CANCER CENTER | $499,252 | Grant | Trans-NIH Recovery Act Research Support: Title: Symptom Cluster Assessment and Intervention Trial Description: This research addresses multiple cancer symptoms (fatigue, insomnia, pain, and depression) during chemotherapy using a specific symptom management protocol. The aims of the study are | Health and Human Services, Department of / National Institutes of Health | 4/29/2009 |
| UNIVERSITY OF WASHINGTON | $452,896 | Grant | Trans-NIH Recovery Act Research Support: Poor quality patient-provider communication contributes significantly to disparities at end of life, particularly among individuals from ethnically diverse or underserved populations. The Aims of this study are to 1) Modify and evaluate the usability of t | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| NATIONAL BUREAU OF ECONOMIC RESEARCH, INC. | $427,839 | Grant | Trans-NIH Recovery Act Research Support: This project will investigate racial and ethnic differences in physical activity (PA). This is important since PA has been shown to have a positive impact on health. Physical activity occurs during leisure-time, household work and market work. Prior studi | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $466,125 | Grant | Trans-NIH Recovery Act Research Support: NPC1 disease is a severe lysosomal lipidosis in which the egress of cholesterol and other lipids from the endosomal/lysosomal (E/L) system is impeded, leading to severe neurodegeneration and premature demise. At present there are no treatment options for | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| UNIVERSITY OF RHODE ISLAND | $397,234 | Grant | Trans-NIH Recovery Act Research Support: Epilepsy, characterized by recurring seizures, is one of the most prevalent neurological disorders in the U.S. Despite decades of research, new anticonvulsant drugs, and advances in surgical therapy, a large number of patients suffer from intractable epil | Health and Human Services, Department of / National Institutes of Health | 5/15/2009 |
| NORTHWESTERN UNIVERSITY | $419,375 | Grant | Trans-NIH Recovery Act Research Support: In this project we will test the hypothesis that pharmacological targeting of kainate receptors, a family of ionotropic glutamate receptors, represents a viable therapeutic strategy in an animal model of multiple sclerosis (MS). Glutamate receptor activat | Health and Human Services, Department of / National Institutes of Health | 5/14/2009 |
| CEREMED, INC. | $99,788 | Grant | Trans-NIH Recovery Act Research Support: With the demand for bone and dental grafts on the rise, demineralized bone matrix (DBM) has been a popular candidate for providing osteoinductive bone repair to defect sites. However, DBM itself has sand like consistencies making it difficult to handle an | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $363,716 | Grant | Trans-NIH Recovery Act Research Support: Francisella tularensis tularensis is a category A select agent for Biodefense Research. It is a highly efficient zoonotic pathogen that has an infectious dose of 10 organisms or less. To accomplish this feat the bacterium has clearly devised efficient m | Health and Human Services, Department of / National Institutes of Health | 5/21/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $390,000 | Grant | Trans-NIH Recovery Act Research Support: A successful cellular immune response to Toxoplasma gondii and many other intracellular pathogens involves a delicate balance between the actions of IL-12, a pro-inflammatory innate cytokine triggered by the parasite and IL-10, a regulatory cytokine produ | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $320,611 | Grant | Trans-NIH Recovery Act Research Support: Energy expenditure is an important neutrally regulated component of energy homeostasis. Alterations in energy homeostasis (imbalance between energy intake and energy expenditure) can result in body weight gain and contribute to the growing epidemic of ob | Health and Human Services, Department of / National Institutes of Health | 6/11/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $994,778 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research and specific Challenge Topic, 04- AA-103: Novel Models of Service Delivery. Nearly 1 in 20 adult women in the U.S. are married to or living with an alcoholic or problem drinking partne | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $493,625 | Grant | Trans-NIH Recovery Act Research Support: The project uses secondary data analyses and simulation studies to investigate the performance of methods for selection of optimal adaptive treatment strategies in alcoholism. We consider Bayesian and causal approaches, and consider up to four treatment s | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| PACIFIC INSTITUTE FOR RESEARCH AND EVALUATION | $996,685 | Grant | Trans-NIH Recovery Act Research Support: Using an innovative technique to assess drinking patterns (oral assays), the purpose of this project is to examine the club as a specific ecological context to assess drinking patterns and related risky behaviors. The club setting attracts young adults wh | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $980,018 | Grant | Trans-NIH Recovery Act Research Support: The main objective of this project is to achieve a better understanding of how alcohol addiction and withdrawal affects neuronal communication in the central nervous system at levels of single neurons and neural circuits. Specifically, the collaborating s | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $671,415 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (05): Comparative Effectiveness Research and specific Challenge Topic: 05-AA-102 Adaptive Designs and Person-Centered Data Analysis for Alcohol Treatment Research. As the challenge topic implies, statistical | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $667,628 | Grant | Trans-NIH Recovery Act Research Support: The study's goal is to compare the effectiveness of a city level policy in New Orleans to control problem alcohol outlets that contribute to health inequalities among poor and minority populations. In 1997 the City of New Orleans adopted a series of polic | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| REDWOOD BIOSCIENCE, INC. | $999,824 | Grant | Trans-NIH Recovery Act Research Support: Low molecular weight small molecules and peptides often have limited therapeutic utility because of poor pharmacokinetic profile and rapid clearance. As a result, there has been a large effort focused on the development of drug delivery systems, including | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WASHINGTON | $999,529 | Grant | Trans-NIH Recovery Act Research Support: The primary goal of the Tracking Disparities in the Effective Delivery of Health Services project is to develop, apply and refine methods that enhance health agencies, policy-makers, researchers, and analysts' ability to track disparities in the effective | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF WASHINGTON | $993,030 | Grant | Trans-NIH Recovery Act Research Support: This application addresses Broad Challenge Area (08) Genomics and Specific Challenge Topic 08-AG-106 Cross-disease research to identify commonly targeted pathways or mechanisms between low incidence, neurogenetic disorders with high incidence, population- | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $900,354 | Grant | Trans-NIH Recovery Act Research Support: Very recently channelrhodopsins, light-gated ion channels we found in 2002 to be phototaxis receptors that mediate light-induced membrane depolarization in Chlamydomonas algae, have been intensively used for non-invasive, highly temporally and spatially r | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF TEXAS AT DALLAS | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: A significant potential exists to modify the structure and function of the aging human brain given intensive mental stimulation and physical activity. Age-related cognitive decline has consistently been identified on frontal lobe measures of executive con | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| NORTHWESTERN UNIVERSITY | $998,464 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06) Enabling Technologies, and specific Challenge Topics, 06-AG-108 Technologies for obtaining genomic, proteomic, and metabolomic data from individual viable cells in complex tissues, and 06-DK-105 Enablin | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| GEORGETOWN UNIVERSITY (THE) | $674,502 | Grant | Trans-NIH Recovery Act Research Support: Brain changes in tinnitus Tinnitus, a mostly whistling, buzzing, or hissing phantom sound perceived in the absence of a corresponding external stimulus, is perceived by about 15% of the adult population, and about 75% of all patients with hearing loss. It | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF SOUTH FLORIDA | $958,517 | Grant | Trans-NIH Recovery Act Research Support: Adapting a web-based eating disorder program for oral health training Abstract This application addresses broad Challenge Area (01): Behavior, Behavioral Change, and Prevention, and specific Challenge Topic, 01-DE-102: Behavioral and Social Intervention R | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $797,374 | Grant | Trans-NIH Recovery Act Research Support: It is known that half of all dental restorations fail within 10 years and replacing them consumes 60% of the average dentist's practice time. Secondary caries and fracture of the restoration are found to be the main reasons for restoration failure. To fac | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| WASHINGTON UNIVERSITY, THE | $994,872 | Grant | Trans-NIH Recovery Act Research Support: Free radicals, or more specifically, reactive oxygen species (ROS), have been proposed as critical mediators of dysfunction and disease for a large number of disorders, including many in the brain related to Alzheimer's disease, accelerated aging, other n | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| PORTLAND STATE UNIVERSITY | $934,196 | Grant | Trans-NIH Recovery Act Research Support: Malaria remains one of the world's deadliest diseases, destroying lives by the millions and staggering families, communities and even nations with a burden that crushes hope. The demoralizing impact of the disease extends beyond the annual body count to e | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THOMAS JEFFERSON UNIVERSITY | $470,424 | Grant | Trans-NIH Recovery Act Research Support: HS chains regulate key physiologic processes and do so by various mechanisms and most notably by restricting the topographical distribution of signaling factors within tissues, but it is not known whether defects in such signal-restriction mechanisms sub | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| SEATTLE CHILDREN'S HOSPITAL | $994,839 | Grant | Trans-NIH Recovery Act Research Support: Comparative Effectivenss Research in Pediatric Rheumatic Diseases: Leveraging CA -- The study of childhood rheumatic conditions has been challenged by disease heterogeneity, poor understanding of underlying pathophysiology, small sample sizes, and limit | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| HENRY FORD HEALTH SYSTEM | $988,103 | Grant | Trans-NIH Recovery Act Research Support: We propose to characterize miRNAs in the serum and joint tissues in a mouse model of osteroarthritis (OA) and in the serum of patients developing osteoarthritis (OA) after ACL injury to identify biomarkers of OA development. Validation of tis panel of mi | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $980,186 | Grant | Trans-NIH Recovery Act Research Support: Challenge Area (11): Regenerative Medicine, and specific Challenge Topic 11-AR-101 Musculoskeletal and Skin Regeneration Every year, over a million Americans are hospitalized for bone fractures at a cumulative cost of over $100 billion when considerations | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $754,311 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks to investigate the degree of institutional variation in the surgical treatment of breast cancer in community hospitals. The majority of surgery for breast cancer is performed in community hospitals yet the majority of research is perfo | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| WASHINGTON UNIVERSITY, THE | $999,078 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic, 08-CA-09-003: Micro-RNAs in Cancer. The objective of this challenge grant is to define the contribution of microRNAs (miRNAs) to transformation in acute myelogenou | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $831,921 | Grant | Trans-NIH Recovery Act Research Support: This application addresses Broad Challenge Area (08) Genomics and Specific Challenge Topic 08-CA-103: Micro-RNAs in Cancer. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by reducing stability and/or translation of fully or par | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CHICAGO, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: The goals of this proposal are (i) to establish a technology platform for generating high-quality, well- validated synthetic antibodies and (ii) to produce the initial set of synthetic antibodies to high-value antigens useful for epigenetic research. Synt | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UTAH STATE UNIVERSITY | $657,816 | Grant | Trans-NIH Recovery Act Research Support: Neurophysiologically-based sound separation for auditory prostheses.' The purpose is to develop methods for improving the performance of hearing aids by incorporating principles derived from studying the processing of sound mixtures by the brain. | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| NATIONAL CHILDHOOD CANCER FOUNDATION | $1,708,950 | Grant | Trans-NIH Recovery Act Research Support: This award supports the therapeutic work for childhood Acute Lymphoblastic Leukemia (ALL), which is the most common childhood cancer and is a leading cause of cancer-related death. This project is designed to 1) validate the key TARGET (Therapeutically A | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $980,096 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (06): Enabling Technologies and specific Challenge Topic, 06-EB-101: Development of minimally invasive image-guided systems. The primary goal of this program is to couple already existing technologies into a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| EMORY UNIVERSITY | $497,082 | Grant | Trans-NIH Recovery Act Research Support: Validation & Pilot Testing of Methods for Assessing Infants' Dietary Pesticide Exposure Despite evidence of widespread dietary exposure among children and adults, little is currently known about dietary exposure of neonates and infants to pesticides. Thi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $976,772 | Grant | Trans-NIH Recovery Act Research Support: Investigating gene x environment interaction using human exposures to O3 & LPS - ARRA This NIEHS challenge grant is written in response to challenge topic 04-ES-102: Investigating gene x environment interaction using controlled human exposures. As stated | Health and Human Services, Department of / National Institutes of Health | 9/26/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $997,628 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge area (15) Translational Science and specific Challenge Topic, 15-CA-101: The Role of Cellular Architecture in Normal and Tumor Cell Biology. New blood vessels are formed throughout life by either vasculogenic or | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| KAISER FOUNDATION HOSPITALS | $996,603 | Grant | Trans-NIH Recovery Act Research Support: The biggest challenge in fighting the obesity epidemic is developing better ways to help individuals that have lost weight maintain their weight loss over many years. This challenge grant provides funding to analyze follow-up data collected 2 -+ years fo | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $4,818 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to elucidate the mechanistic basis of ocular morphogenesis in vertebrates. During ocular morphogenesis, the optic primordia undergo a complex series of morphogenetic movements that ultimately result in a bilayered opt | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| SMITH-KETTLEWELL EYE RESEARCH INSTITUTE, THE | $277,097 | Grant | Trans-NIH Recovery Act Research Support: Using a variety of techniques including functional brain imaging, EEG and psychophysics to study how color signals are processed and represented in the early human visual system. | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| PENNSYLVANIA STATE UNIVERSITY, THE | $107,609 | Grant | Trans-NIH Recovery Act Research Support: Helicases are enzymes whose activities are essential to DNA replication, homologous recombination, D-loop strand invasion and replication for restart. In so far as these events are central to cell division in how helicases in particular function in normal | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $452,013 | Grant | Trans-NIH Recovery Act Research Support: The approach of this highly collaborative grant is to combine the chemistry program of William Fenical at the Scripps Institution of Oceanography with the antibiotics pharmacology and discovery program of Victor NizetG??s laboratory at the UCSD School of | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $91,041 | Grant | Trans-NIH Recovery Act Research Support: Over the past granting period we have for the first time obtained crystal structures of holoenzyme complexes of PKA. These complexes of the catalytic subunit bound to RI1, RII1 and RII have not only allowed us to understand how the catalytic subunit is in | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $241,277 | Grant | Trans-NIH Recovery Act Research Support: This supplement builds directly on, and significantly extends the translational impact of Specific Aim 1 in the parent R01 grant: investigating the functional importance of the PX domain of p47phox and PI 3-kinase signaling in NADPH oxidase priming and ac | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $269,381 | Grant | Trans-NIH Recovery Act Research Support: Programmed cell death plays a central role in development and in many diseases. The long term goal of our research is to understand the mechanisms of programmed cell death in the Drosophila ovary, a model system with unique advantages in genetics and cell | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| CALIFORNIA INSTITUTE OF TECHNOLOGY | $426,627 | Grant | Trans-NIH Recovery Act Research Support: The request is to fund additional research that promises to accelerate progress in this grant by a totally novel approach in two of the key Specific Aims of the parent grant. These Aims are, briefly, to generate and test the logical sufficiency of spatia | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $239,747 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the parent grant is to determine the role of the TraI protein in the transfer of the F plasmid between bacteria. In addition to chromosomes, bacteria can possess pieces of DNA called plasmids. Some plasmids, such as the F plasmid we study, | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| UNIVERSITY OF UTAH, THE | $735,382 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): This application addresses the broad Challenge Area (15): Translational Science and the specific Challenge Topic 15-DK-102: Develop improved animal models of NIDDK diseases. Metabolic homeostasis plays a central role i | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| CHILDREN'S HOSPITAL CORPORATION, THE | $995,737 | Grant | Trans-NIH Recovery Act Research Support: This proposal will evaluate a new test, the serum hepcidin, as a screen for ID in infants. Furthermore, using the same dataset, we will address the possibility that variants in the gene encoding TMPRSS6, a protein that modulates hepcidin production, could | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BROAD INSTITUTE, INC., THE | $998,425 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (08) Genomics and specific Challenge Topic 08-DK-106 : Genomics of complex diseases. The innate immune system is the first-line of defense against harmful bacteria and viruses. It senses foreign invaders th | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $878,055 | Grant | Trans-NIH Recovery Act Research Support: The biochemistry of iron transport is not thoroughly understood. Although iron deficiency is the most prevalent nutritional problem in the U.S., 1 in 20 Caucasians carry genetic variants of HFE alleles that promote susceptibility to iron overload. Thus, t | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $475,105 | Grant | Trans-NIH Recovery Act Research Support: The application addresses broad challenge area Model organisms for social behavior studies: Identification and development of model organisms that allow for integrative analyses of the genetic, biochemical, physiological, and environmental components of s | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $994,690 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational science and specific Challenge Topic, 15-DK-102: Develop improved animal models of NIDDK diseases. Hepatitis C virus (HCV) is an agent of chronic liver disease, and affects an estimated 3% | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $499,384 | Grant | Trans-NIH Recovery Act Research Support: We now hypothesize that kidney fibrosis is a state of functional pericyte deficiency and we further hypothesize that pericyte loss explains peritubular capillary rarefaction in fibrosis. In AIM 1 we will establish the function of kidney pericytes in vivo | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF NEW MEXICO | $967,042 | Grant | Trans-NIH Recovery Act Research Support: This project is in direct response to '06-EB-104 - Fast MR Imaging for Routine Clinical Examinations'. We will develop a novel ultra high-speed 3D MR spectroscopic imaging (MRSI) exam to map total Choline (tCho), a sensitive biomarker of breast tumor stat | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| SCRIPPS RESEARCH INSTITUTE, THE | $999,998 | Grant | Trans-NIH Recovery Act Research Support: Multimeric, polyspecific protein therapeutics are difficult to design and produce. The ability to link binding, effector, and imaging components together in a single molecule would be a significant advantage. We propose to develop unnatural amino acid-oli | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| TEXAS HEART INSTITUTE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Adult stem cell based therapies (using a patient's own cells, not embryonic cells) have emerged as a promising approach in regenerative medicine. The ability to track transplanted stem cells after they are injected into the body is a crucial tool because | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $844,027 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Heparan sulfates (HS) are abundant and molecularly complex sugars of the extracellular space. They are involved in regulating cell-cell interactions, for example by modulating growth factor signaling or regulating the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TEXAS TECH UNIVERSITY SYSTEM | $809,695 | Grant | Trans-NIH Recovery Act Research Support: At this point, we continue mostly with the analysis. We are teaching one section of PHYS 2401 with interactive engagement and lecture/lab integration and are continuing the administration of one of the conceptual inventories as a pre- and post- test in bo | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $767,805 | Grant | Trans-NIH Recovery Act Research Support: The origins of human diseases, such as cancer, can be generally attributed to loss-of-function of important genes (tumor suppressor genes) and/or gain-of-function of pathological genes (oncogenes). We are interested in understanding how animal cells use s | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $903,718 | Grant | Trans-NIH Recovery Act Research Support: The project of this grant is for the development of a quantum mechanics-based force field for simulations of biomolecular systems. The current generation of force fields used in essentially all atomistic molecular dynamics simulations of proteins and nuc | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OKLAHOMA MEDICAL RESEARCH FOUNDATION | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: The objectives of this proposal are: (1) to validate extracellular histones as important biomarkers that mediate of tissue damage, ultimately leading to organ failure, and (ii) characterize the therapeutic potential of two histone blocking strategies. Aim | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $610,295 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15) Translational science and Specific Challenge Topic: (15-TW-101) Models to predict health effects of climate change. We propose to develop Bayesian hierarchical statistical methods and software that will | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CORNELL UNIVERSITY, INC | $999,891 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area 01: Behavior, Behavioral Change, and Prevention, and specific Challenge Topic 01-OD-101: Test default options to promote healthier behaviors. We propose a set of three related studies that target two critica | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OHIO STATE UNIVERSITY, THE | $998,715 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (04) Clinical Research, and the specific Challenge Topic, 04- DA-102: 'A New Look at Longitudinal Data'. This effort will not only jumpstart entirely new lines of research by substantially expanding the brea | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $939,401 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (08) Genomics, and specific Challenge Topic, 08-OD-101, Computational approaches for epigenomic analysis. While the primary DNA sequence of the human genome is ultimately responsible for the encoding and fun | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF IOWA, THE | $847,690 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic, 01-GM-104: Mechanisms of Behavior Change Research. Disclosing the prospect or discovery of genomic IFs to clinical patients or p | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $850,201 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision is submitted in response to Notice Number NOT-OD-09-058, 'Enabling RPGs to Leverage NCRR Center and Center-like Programs' and 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications.' Infants b | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NATIONAL JEWISH HEALTH | $999,999 | Grant | Trans-NIH Recovery Act Research Support: We propose to build a new paradigm for advancing and transforming patient care through development of cell-based therapies for human lung disease. Analysis of acute lung injury in mice indicates that epithelial damage can precede loss of alveolar structur | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $719,328 | Grant | Trans-NIH Recovery Act Research Support: In work to understand how blood is patterned in early mesoderm, we have discovered that a cocktail of transcription factors interacts synergistically to cause cells that do not have the potential to become blood to convert to blood at high efficiency. W | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| VIRTUAL REALTY AIDS INC | $999,929 | Grant | Trans-NIH Recovery Act Research Support: Autism is a complex neurological disorder that affects 1.5 million individuals in this country. While services for children with Autism Spectrum Disorders (ASD) are supported by federal mandates, as these children transition into adulthood and independent | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| EMORY UNIVERSITY | $797,069 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (01) Behavior, Behavioral Change, and Prevention and specific Challenge Topic 03-MH-101* Biomarkers in mental disorders. The major hypothesis is that post-traumatic stress disorder (PTSD) leads to a reductio | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $999,499 | Grant | Trans-NIH Recovery Act Research Support: This application addresses the broad Challenge Area 03: Biomarker Discrimination and Validation, and the specific challenge topic: 03-MG-101, Biomarkers of mental disorders. Schizophrenia, a devastating psychiatric disorder, is chiefly characterized by po | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE, INC. | $877,075 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this study is to increase our understanding of the determinants of daily functioning in bipolar disorder. We plan to recruit 48 subjects with bipolar disorder, 36 subjects with schizophrenia, and 36 normal controls. All subjects will par | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| WASHINGTON UNIVERSITY, THE | $762,134 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (03) Biomarker Discovery and Validation, and specific Challenge Topic, 03-MH-101 Biomarkers in mental disorders. The variability of treatment outcome in PTSD, the high risk of relapse and the fact that only | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $996,692 | Grant | Trans-NIH Recovery Act Research Support: This application entitled 'Development of a Brief Screener for Research in Autism Spectrum Disorders' addresses broad challenge area (04) Clinical Research, 04-MH-101* Autism: Addressing the challenge. The proposal aims to develop a research screening ins | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $999,377 | Grant | Trans-NIH Recovery Act Research Support: This project titled 'Validating resting state fMRI derived brain connectivity' represents a large scale effort to establish rigorously the reliability of brain connectivity measures derived from resting state fMRI (fcMRI). This method of studying the spat | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO | $962,011 | Grant | Trans-NIH Recovery Act Research Support: Exposure to trauma, especially when it manifests as Post-Traumatic Stress Disorder, results in numerous negative consequences for patients, families, and society. Some of the most frequent, disturbing, and treatment resistant symptoms of PTSD are nightmar | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $996,035 | Grant | Trans-NIH Recovery Act Research Support: This application addresses broad Challenge Area (15): 15-NS-103, 'Demonstration of 'proof-of-concept' for a new therapeutic approach in a neurological disease.' Children with inherited lysosomal storage disorders (LSDs) affecting the central nervous syste | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF PRINCETON UNIVERSITY, THE | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: Virtual reality (VR) is widely used in human behavior and neuro-imaging experiments. We propose to bring this technology to bear on diverse areas in the study of neural circuits at cellular resolution in rodents. We'll develop VR instrumentation and softw | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CINCINNATI | $278,729 | Grant | Trans-NIH Recovery Act Research Support: This competitive revision will stringently adhere to the ARRA by retaining the position of a Research Associate and creating one position for a Research Assistant and a part-time position for an undergraduate student and stimulating the economy through th | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $180,084 | Grant | Trans-NIH Recovery Act Research Support: A research assistant, Ingrid Rosario, has been hired as of mid-October to assist with study coordination and ongoing research efforts. She has completed training in human subjects research as well as our own study protocols and has taken over responsibili | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $345,244 | Grant | Trans-NIH Recovery Act Research Support: Some environmental toxicants are alkylating agents that can damage DNA. If left un-repaired, DNA alkylation damage can lead to mutation, cell death, and can promote carcinogenesis. Fortunately, most cells can prevent the detrimental effects of alkylating | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF PITTSBURGH THE | $218,268 | Grant | Trans-NIH Recovery Act Research Support: The requested administrative supplement will be used to support the full time employment of a senior level research scientist (Level IV) and to procure new equipment needed for the specialized PCR based assay that is required for the project. The purpose | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $539,132 | Grant | Trans-NIH Recovery Act Research Support: Most complex diseases have genetic causes, but observations from families and especially from twins indicate that other factors are almost always necessary for the actual appearance of disease. One such factor appears to be the proportion of DNA units tha | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $405,700 | Grant | Trans-NIH Recovery Act Research Support: The proposed project will supplement an ongoing comprehensive, population-based case-control investigation of underlying causes for autism and triggers of regression. This project, known as the CHARGE (Childhood Autism Risks from Genetics and Environment | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $480,980 | Grant | Trans-NIH Recovery Act Research Support: This Competitive Revision aims to greatly enhance our ability to estimate lifetime and age-specific solar ultraviolet (UV) exposures obtained retrospectively from self-report and enhance the novel UV exposure metric that we developed for, and are using in | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $295,200 | Grant | Trans-NIH Recovery Act Research Support: The goals of our research program are to determine which interventions are most effective at reducing the burden of mortality and morbidity among women and children in high-risk populations in developing countries. At our field site in southern Nepal, acu | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $392,059 | Grant | Trans-NIH Recovery Act Research Support: The proposed project will add new equipment and new staff to a currently funded research study (1 R01 ES015579-01A2) that aims to assess the effects of pre- and postnatal exposure to the organophosphorus pesticide chlorpyrifos on brain development and pat | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| UNIVERSITY OF NEW MEXICO | $629,143 | Grant | Trans-NIH Recovery Act Research Support: This project is in response to NOT-OD-09-058 'NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications' and represents an extension of R01 ES015826 (K.J. Liu, PI; L.G. Hudson, co-investigator) 'Arsenic-enhanced skin carci | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF RHODE ISLAND | $236,235 | Grant | Trans-NIH Recovery Act Research Support: Hepatic biliary excretion is an essential process that exists to aid the in the elimination of foreign chemicals, and protects the body from accumulating chemicals and toxicants. Understanding the underlying processes by which specific transporters that a | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF CALIFORNIA MERCED | $219,459 | Grant | Trans-NIH Recovery Act Research Support: This ARRA request is for an administrative supplement to an existing R01 project grant that is intended to accelerate the pace of research of a 3-YR project currently in progress. The overall aim of this project is basic research into the use of reactive | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF MONTANA SYSTEM | $266,467 | Grant | Trans-NIH Recovery Act Research Support: This supplement project will afford us the opportunity to address our biggest needs in the following two aims: 1) increase our subject recruiting, data collection,and data analysis capacity by hiring additional staff, including a postdoctoral fellow and | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $99,999 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA equipment supplement to R01 EY005911 entitled, Visual Processing in the Cerebral Cortex. It covers the purchase of 4 video-based eye position monitors for use in neurophysiological research on how attention affect the way that the cerebra | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $167,204 | Grant | Trans-NIH Recovery Act Research Support: To understand the computations that take place in the human visual system and ultimately palliate disorders, it is essential to know how the system works in natural situations. Despite the immense success of neurophysiological research over the past forty | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | $63,561 | Grant | Trans-NIH Recovery Act Research Support: The proposed equipment is a cost-effective approach that takes advantage of existing equipment (largely NEI-funded) and our experience with it. It has been custom-designed with specific features that recognize the needs of the several experimental lines | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| WASHINGTON UNIVERSITY, THE | $639,681 | Grant | Trans-NIH Recovery Act Research Support: This ARRA-supported project (3R01 EY012543-10S1) investigates the role of the retinal transcription factor CRX in photoreceptor development, maintenance and diseases. CRX is a key member of the photoreceptor transcription factor network that regulates the | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FORDHAM UNIVERSITY | $99,074 | Grant | Trans-NIH Recovery Act Research Support: It is the long-term goal of this research project to identify molecular mechanisms used by the retinal pigment epithelium (RPE) to phagocytose photoreceptor outer segment fragments (POS) shed in a circadian rhythm in the mammalian eye and to understand ho | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| WICAB, INC | $139,183 | Grant | Trans-NIH Recovery Act Research Support: VISION SUBSTITUTION THROUGH THE TONGUE | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $323,623 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The broad, long-term objective of this proposal is to define in molecular terms the linkage between the oxidative modifications of proteins in the outer retina, their recognition by the immune system and the vulnerabil | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $230,418 | Grant | Trans-NIH Recovery Act Research Support: How do thalamic neurons integrate their various feedforward and feedback inputs? Most of the inputs and synapses in the mammalian lateral geniculate nucleus (LGN) are extra-retinal, but the way in which these diverse inputs are integrated to control the f | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $484,544 | Grant | Trans-NIH Recovery Act Research Support: This is a competitive revision in response to notice NOT-OD-09-058 entitled NIH announces the availability of recovery act funds for competitive revision applications The long-term objective of this grant is to identify cell-matrix signaling mechanisms th | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $667,195 | Grant | Trans-NIH Recovery Act Research Support: A major stated research priority of the National Eye Institute is 'to identify the genes involved in retinal degenerative diseases'. Although numerous genes causing retinal degeneration have been discovered, many remain to be identified, and novel approac | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $408,692 | Grant | Trans-NIH Recovery Act Research Support: A major contribution to ocular morbidity is lacrimal dysfunction, affecting over 10 million Americans. The principal cell of the lacrimal gland and primary contributor of proteins into ocular surface fluid is the lacrimal acinar cell, which is the target | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $176,760 | Grant | Trans-NIH Recovery Act Research Support: The long-term goals of this project are to develop spectroscopic methods for probing electric fields in proteins and to apply these methods to obtain quantitative information on fields and their effects on function at the active sites of several enzymes a | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $191,868 | Grant | Trans-NIH Recovery Act Research Support: Retrotransposons constitute a large percentage of eukaryotic genomes, but their replication and impact on host cells is not well understood. Ty3 offers a unique model system with which to understand how these elements replicate and transpose within cells. | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF KENTUCKY | $112,602 | Grant | Trans-NIH Recovery Act Research Support: The co-translational N-glycosylation of many important cell surface receptors, ion channels and lysosomal enzymes is essential for their correct folding, intracellular routing and function in the CNS and other mammalian cells. The vital importance of prot | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $137,492 | Grant | Trans-NIH Recovery Act Research Support: We are requesting supplemental funds to our parent grant, focused on the estimation of the mutation rate and the full molecular spectrum of mutations in several model species, to support two key personel: a laboratory technician to ensure the proper prepa | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $122,765 | Grant | Trans-NIH Recovery Act Research Support: The motility of eukaryotic cilia and flagella is known to depend on dynein ATPase motors that move along doublet microtubules. Flagellar dyneins must be regulated to coordinate their activity during normal bend formation and propagation, and additionally | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MICHIGAN STATE UNIVERSITY | $259,165 | Grant | Trans-NIH Recovery Act Research Support: The long-term objective of the proposed work is the elucidation of the mechanism of DNA replication in animal mitochondria, and its relationship to mitochondrial mutagenesis and human disease. A combined approach of current methods in biochemistry and mol | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $270,364 | Grant | Trans-NIH Recovery Act Research Support: The broad long term objectives of the grant are to use NMR to provide insight into how variations in amino acid sequence affect conformation, dynamics, and folding of the collagen (Gly-X-Y)n triple helix motif. These studies will be applied to understand | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $247,190 | Grant | Trans-NIH Recovery Act Research Support: Award title: The Ribonucleic acid polymerase II transcription complex - The purpose of this award is to support the lab(s) research into the basic mechanisms of gene expression. This project focuses on the Ribonucleic acid polymerase transcription machine | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $95,000 | Grant | Trans-NIH Recovery Act Research Support: As described in the previous reported, this supplement is focused on the CtIP protein. This supplemental application outlined a request for an upgrade to one of our two light microscopes for work covered under Aims 2 and 3. During the past two years of t | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $123,892 | Grant | Trans-NIH Recovery Act Research Support: Cell migration is essential for normal embryonic development, tissue repair and immune surveillance, but is also a contributing factor in mental retardation, developmental defects, tumor cell invasion and tissue fibrosis. It is a highly dynamic process re | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WAKE FOREST UNIVERSITY | $207,458 | Grant | Trans-NIH Recovery Act Research Support: The long term goals of this grant are to test mechanisms of pain transmission in the spinal cord of humans and to test whether experimental pain models in animals and humans predict efficacy of spinal analgesics in clinical pain states. We focus on the sp | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $113,134 | Grant | Trans-NIH Recovery Act Research Support: Calcineurin, the Ca2+/calmodulin dependent protein phosphatase, is a critical component of Ca2+ dependent signal transduction that promotes survival during environmental stress conditions in yeast. We identified a novel substrate of calcineurin, Aly1, whi | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $113,259 | Grant | Trans-NIH Recovery Act Research Support: This is an Administrative Supplement Award for our collaborative project with Dr. Pei Tang at University of Pittsburgh School of Medicine to add Nuclear Magnetic Resonance (NMR) approach into our study. In this project, we will systematically investigate | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MISSOURI SYSTEM | $327,700 | Grant | Trans-NIH Recovery Act Research Support: During the past funding on this award, we have generated strong data to support the conclusion that the macrophage ubiquitination-proteasome pathway functions as a key regulator of LPS-induced signaling through Toll-like receptor 4 (TLR4). In addition, we | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $215,522 | Grant | Trans-NIH Recovery Act Research Support: The primary purpose of this supplemental award is to allow us to purchase a fluorescence microscope. We plan to use the microscope to visualize gene transfer between individual bacterial cells. It will also support a postdoctoral researcher (for 1.5 yea | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $214,057 | Grant | Trans-NIH Recovery Act Research Support: The objectives of the proposed research are to identify proteins that play general and important roles in transcription by RNA polymerase II (pol II) and to elucidate the mechanisms by which these proteins act. This grant focuses on the highly regulated | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $65,981 | Grant | Trans-NIH Recovery Act Research Support: Relevance Cells show extraordinary diversity in size and shape. Generation of diverse sizes and shapes requires regulation of the amount and location of growth, as well as coordination of growth with the cell cycle. The mechanisms by which cells regulate | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| MONTANA STATE UNIVERSITY, INC | $335,598 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this project is to delineate the detailed chemical mechanism of radical generation by the Fe/S-S-adenosylmethionine (the so-called radical SAM) superfamily of enzymes. These enzymes span a remarkably diverse range of reactions and | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $199,364 | Grant | Trans-NIH Recovery Act Research Support: Project Aims: Central to the design of site-specific inhibitors and modulators of aminoacyl-tRNA synthetases is the question of whether these-? enzymes employ a relatively limited number of different catalytic strategies, or if unique catalytic strategies | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $43,060 | Grant | Trans-NIH Recovery Act Research Support: Interleukin-2 (IL-2) is a cytokine that functions in the mammalian immune response to infection. During an immune response, production of IL-2 is upregulated at the level of transcription by activators such as NFAT1 and cJun. The main goal of this researc | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $81,616 | Grant | Trans-NIH Recovery Act Research Support: This project focuses on protein phosphatase-1 (PP1) and inhibitor-2 (Inh2) that localize to centrosomes and have essential and critical roles in mitosis. Understanding the role of these proteins in mitosis will impact the use of mitotic kinase inhibitors | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $213,912 | Grant | Trans-NIH Recovery Act Research Support: Aneuploidy is the leading cause of miscarriages in humans and a hallmark of cancer. Determining the origins and effects of aneuploidy is thus vital for understanding the principles underlying tumor formation and infertility. We had previously examined the | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| MICHIGAN STATE UNIVERSITY | $211,028 | Grant | Trans-NIH Recovery Act Research Support: Transcriptional repression plays a key role in regulation of gene expression in development and in disease processes. To understand conserved regulatory processes in animals, we have determined both the molecular workings and physiological relevance of tr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| WASHINGTON UNIVERSITY, THE | $253,425 | Grant | Trans-NIH Recovery Act Research Support: Perhaps one half of disease gene alleles are the result of mutations in non-coding sequence, rather than in protein coding sequences. Understanding the nature of disease, developing reliable diagnostics for disease, and relating different alleles to diff | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $115,068 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): We propose to study two major mechanisms that regulate the structure and function of the plasma membrane: ER quality control and lipid rafts. We have used mutants of PMA1 encoding the yeast plasma membrane H+ATPase as | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SANTA CRUZ | $151,756 | Grant | Trans-NIH Recovery Act Research Support: Over the past five years, our laboratory has developed numerous approaches to study the regulation of pre-mRNA splicing using C. elegans as a model system. Alternative splicing is a key mechanism for controlling gene expression and creating diversity in t | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $44,080 | Grant | Trans-NIH Recovery Act Research Support: G?? This is the final report for this award. The project is complete and all awarded funds have been exhausted. | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $49,814 | Grant | Trans-NIH Recovery Act Research Support: The ability of stem cells to develop into a large variety of different cell types holds great promise for treatment of many human diseases. Furthermore, the control of the growth of stem cells and other unspecified cells is critical to prevent the develop | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $119,967 | Grant | Trans-NIH Recovery Act Research Support: YidC is an evolutionarily conserved protein involved in the membrane biogenesis of respiratory proteins, energy transduction proteins, ATPases, signaling molecules and transporters. YidC can function as a membrane insertase either independently or cooper | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $230,934 | Grant | Trans-NIH Recovery Act Research Support: The project involves the set-up of a two-photon microscope for axial-drift compensated cell measurements. Once the instrument is set-up the performance will be characterized using axial z-scan fluorescence fluctuation measurements. A method that determine | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $181,674 | Grant | Trans-NIH Recovery Act Research Support: Glutamate transporters (EAATs) play an important role in the regulation of extracellular levels of glutamate, a major excitatory neurotransmitter in the central nervous system. Current data show that glutamate transporter type 3 (EAAT3) in the hippocampus | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| FLORIDA STATE UNIVERSITY, THE | $78,340 | Grant | Trans-NIH Recovery Act Research Support: Purpose of the supplement: The purpose of the supplement award is to upgrade the main X-band EPR instrumentation supporting the parent grant. It is possible to make the upgrade at modest cost because an X-band magnet and power supply exist in my lab as b | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| LOYOLA UNIVERSITY | $317,688 | Grant | Trans-NIH Recovery Act Research Support: The purpose of this award is to test the hypothesis that acetylation of RNA polymerase impacts the ability of bacterial cells to control transcription. The outcome is expected to be a dramatic alteration of our understanding of bacterial gene expression. | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $114,702 | Grant | Trans-NIH Recovery Act Research Support: Activation of the stress pathway and engagement of the apoptotic program represent two fundamental cellular responses to damage. Coordination of the cellular stress response is mediated by the transcriptional activity of heat shock factor-1 (HSF-1), the p | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $76,314 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to understand the mechanism by which calcium alters the size and shape of ciliary and flagellar bends to control motility. In mammals, motile cilia / flagella are required for sperm propulsion, removal of debris from the respir | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF RHODE ISLAND | $24,939 | Grant | Trans-NIH Recovery Act Research Support: In this summer supplement, a unique sample of 213 preterm infants, grouped by perinatal morbidity, are seen at age 23. This is the eighth wave of the project, with participants seen at birth, 18 months, 30 months, ages 4, 8, 12, 17, and now, at age 23. U | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| TEXAS A & M RESEARCH FOUNDATION | $18,415 | Grant | Trans-NIH Recovery Act Research Support: This supplement was issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators, supporting NIH/NIDDKD parent grant 3R21DK078571, Biochemical and Molecular Analys | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $16,068 | Grant | Trans-NIH Recovery Act Research Support: The broad, long-term objective of this research is to develop an implantable construct for peripheral nerve regeneration following nerve trauma. Peripheral neurons can regenerate their axons after nerve injury and reinnervate peripheral targets. Despite t | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| RFCUNY - BARUCH COLLEGE | $29,927 | Grant | Trans-NIH Recovery Act Research Support: As the developing world continues to urbanize, and Africa and Asia approach the point at which they will become more urban than rural, new investments in demographic data and research methods will be required to understand and address the public health an | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| UNIVERSITY OF PITTSBURGH THE | $297,513 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of this competitive revision is to extend the scope of the currently funded Pocket PATH project beyond patient behaviors to also support the clinician behaviors known to promote better health outcomes through collaboration and partners | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $189,440 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this proposal is to investigate the role of adenosine (ADO) in cerebral blood flow (CBF) regulation. ADO is a purine nucleoside and breakdown product of ATP via AMP. In our most recent grant, we (1) defined the ADO receptor subtype inv | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $86,565 | Grant | Trans-NIH Recovery Act Research Support: Specific Aims 1A: Identify additional nuclear DNA pathogenic complex I gene mutations. Specific Aim 2A: Isolate additional deleterious mtDNA mutations in mouse cells and introduce those most similar to human pathogenic mutations into the mouse. Specific | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF ILLINOIS | $157,000 | Grant | Trans-NIH Recovery Act Research Support: Exceptional progress has been made during the previous three years of funding under the parent grant entitled G?Molecular Mechanisms of Axonal TransportG? in identifying functional domains on the kinesin heavy and light chains important for regulation of | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $246,513 | Grant | Trans-NIH Recovery Act Research Support: The awarded project intends to create a new technician position for my existing RO1 award (HL088243) supported by NIH/NHLBI to accelerate the tempo of the research. The parent grant aims to elucidate the role of excessive Ca influx through the L-type calc | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $118,657 | Grant | Trans-NIH Recovery Act Research Support: The major goal of HD038075 G?Environmental Influences on Early Reading: A Twin StudyG? is to examine the genetic and environmental influences on the developmental trajectory of reading decoding and comprehension and its correlates from early elementary sc | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF PITTSBURGH THE | $91,163 | Grant | Trans-NIH Recovery Act Research Support: Our team developed a theory-based 'Reproductive-health Education and Awareness of Diabetes in Youth for Girls' (READY-Girls) program tailored specifically for teen women with T1D as a CD and book. This Supplement will provide funding for a student to work | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| KENT STATE UNIVERSITY | $108,339 | Grant | Trans-NIH Recovery Act Research Support: Remarkably little is known about factors related to parenting and child outcomes among Latina adolescent mothers. Understanding these factors is critical in light of the fact that the birth rate for Latino youth is substantially larger than that for any o | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $72,682 | Grant | Trans-NIH Recovery Act Research Support: The supplementation of vitamin D (vitD) during lactation has been poorly investigated: An expert panel convened by the CDC released a report stating that there are insufficient data to evaluate vitD supplementation requirements during lactation. A CDC stu | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CORNELL UNIVERSITY, INC | $26,000 | Grant | Trans-NIH Recovery Act Research Support: The mesodermal germ layer gives rise to a variety of functionally important cell types, including different muscle and non-muscle cells. Elucidating how different mesodermal cell fates are specified is not only important to the understanding of early stag | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $145,316 | Grant | Trans-NIH Recovery Act Research Support: Genome duplication is an important speciation mechanism for all eukaryotes, especially animals and plants. On one hand, genome duplication provides additional genetic material for adaptive evolution and natural variation; on the other, genome duplication | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $251,582 | Grant | Trans-NIH Recovery Act Research Support: The broad, long-term objective of this work is to gain insight into how proteins modulate the structure, dynamics and function of RNA in ribonucleoprotein (RNP) complexes in general, and into the mechanism of the RNA-based tRNA processing enzyme, RNase P, | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MARQUETTE UNIVERSITY | $71,092 | Grant | Trans-NIH Recovery Act Research Support: This application is a response to the solicitation with notice number NOT-OD-09-058 and notice title G?NIH Announces the Availability of Recovery Act Funds for Administration SupplementG?. The goal is to advance a versatile universal docking principle eme | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WASHINGTON UNIVERSITY, THE | $201,488 | Grant | Trans-NIH Recovery Act Research Support: The alternative packaging of DNA into euchromatic and heterochromatic forms can be stably maintained in differentiated cells, and represnts an important form of epigenetic inheritance. Heterochromatin packaging is dependent on an interacting set of struct | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $27,000 | Grant | Trans-NIH Recovery Act Research Support: The Gly380?Arg mutation in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) is linked to achondroplasia, the most common form of human dwarfism in more than 97% of all studied cases. We are seeking the physical basis behind the diso | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $109,447 | Grant | Trans-NIH Recovery Act Research Support: Regulation of mRNA stability plays a critical role in the control of gene expression. Dysregulated mRNA turnover has been implicated in various pathological processes. Understanding the regulation of mRNA decay should provide insights into the pathogenesi | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF WASHINGTON | $97,013 | Grant | Trans-NIH Recovery Act Research Support: We are requesting an administrative supplement to expand our parent R01 entitled microtubule dynamics and chromosome segregation (GM 069429) to take advantage of echinoderms in order to study the role of regulators of microtubule dynamics in the process o | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $196,423 | Grant | Trans-NIH Recovery Act Research Support: The supplement seeks to accelerate the achievement of Aim 1 of the parent grant, whose overall goal was to analyze the conformational changes occurring upon substrate binding in the hetero-octameric phosphofructokinase (Pfk) from S. cerevisiae by 3D cryo- | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $94,049 | Grant | Trans-NIH Recovery Act Research Support: This proposal is a supplement to GM069783 RO1, entitled ?pH-Triggered Membrane Insertion of Proteins?, which is focused on deciphering the molecular mechanism of refolding and membrane insertion of the diphtheria toxin T-domain (DTT) and of annexin B12 (A | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| DUKE UNIVERSITY | $98,012 | Grant | Trans-NIH Recovery Act Research Support: The broad long-term goal of this administrative supplement funded project is: We will improve our understanding of the emergence of S. cerevisiae as an opportunistic pathogen via analysis of a novel genetically complex virulence trait, the ability to grow | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| RFCUNY - CITY COLLEGE | $84,010 | Grant | Trans-NIH Recovery Act Research Support: Research Project: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in a n area representing his specific interest and competencies. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $93,577 | Grant | Trans-NIH Recovery Act Research Support: p38-mediated defense pathway against pore-forming toxins. The purpose of the award is to determine which genes are involved in immune protection against pore-forming toxins. Pore-forming toxins (PFTs) are the largest class of protein toxins secreted by | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF SOUTHERN CALIFORNIA | $232,255 | Grant | Trans-NIH Recovery Act Research Support: Interactions between the human genome and the environment have shaped the evolution of complex human phenotypes. Since the emergence of the genus Homo, there have been many significant changes in the interactions of humans and their ancestors with their e | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $78,152 | Grant | Trans-NIH Recovery Act Research Support: In the post-genome era, it is critical to organize genes and proteins into functional biological networks. Our long-term goal is to dissect the transcriptional regulatory networks that regulate every biological process in the cell, understand the regulato | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $111,192 | Grant | Trans-NIH Recovery Act Research Support: Among the myriad protein interaction domains, PDZ domains, (structural domain of 80-90 amino-acids) are one of the most frequently encountered. They are often found in combination with other interaction modules and play a role in establishing cell polarit | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $155,913 | Grant | Trans-NIH Recovery Act Research Support: The goals of the parent project are to design, synthesize and characterize a novel series of expanded purine and extended pyrimidine nucleosides and to incorporate them into DNA helices. Once incorporated, they will be spectroscopically, thermodynamically | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $71,870 | Grant | Trans-NIH Recovery Act Research Support: The biochemical and structural work proposed here will provide the bases to understanding the nucleation mechanism of Lmod, a novel actin filament nucleator discovered with support from R01 GM073791. Thespecific isoform of Lmod studied here (cardiac Lmod2 | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $76,527 | Grant | Trans-NIH Recovery Act Research Support: There are two major goals for this project: 1) confirm the role of Msr1 during inflammation. 2) Map additional genes that regulate the inflammatory process in a more clinically relevant murine model of sepsis: cecal ligation and puncture. In addition, | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF UTAH, THE | $278,208 | Grant | Trans-NIH Recovery Act Research Support: PoROvVTIDi?ED. In eukaryotes, the 'multivesicular body' (MVB) pathway delivers transmembrane proteins and lipids into the lumen of the lysosome for degradation. As a consequence, MVBs are essential for regulating cell surface protein composition and maint | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $54,263 | Grant | Trans-NIH Recovery Act Research Support: We are focused on two general areas of chemical synthesis: 1) regioselective and stereospecific metal-mediated nucleophilic addition reactions and 2) regioselective cycloaddition reactions. The purpose of the AFFA funds was to purchase two pieces of chrom | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $94,198 | Grant | Trans-NIH Recovery Act Research Support: During Xenopus gastrulation, the modulation of adhesive properties within and between the germ layers controls cell-cell and cell-extracellular matrix interactions to regulate morphogenesis. Cell adhesion molecules such as cadherins, protocadherins and in | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF ARIZONA | $96,386 | Grant | Trans-NIH Recovery Act Research Support: The proposed Administrative Supplement will accelerate the tempo of scientific research and the achievement of additional research objectives by retaining existing and hiring new personnel to work within the scope of the parent grant's Aim 1a: to develop | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $136,466 | Grant | Trans-NIH Recovery Act Research Support: The staggering functional and anatomical complexity of the vertebrate brain arises gradually during embryonic development from an initially uniform field of cells. We would like to understand the early steps of brain development, in particular, formation | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $242,875 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Gene targeting is a procedure in which an existing chromosomal segment is replaced with a corresponding segment that has been altered in the laboratory. This allows introduction of designed mutations into genes of mode | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF ROCHESTER | $206,888 | Grant | Trans-NIH Recovery Act Research Support: The administrative supplement will be used to hire a postdoctoral associate, who will work on Aim #3 of the original award. The postdoctoral researcher is essential to the project, as the graduate students working on the grant are in the first half of th | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF CINCINNATI | $246,973 | Grant | Trans-NIH Recovery Act Research Support: Transplantation of tissue-engineered skin grafts has delivered new medical benefits to patients with acute skin wounds arising from extensive, full-thickness burns, but applications of these devices to elective surgery (i.e., burn scars) is compromised by | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| HEALTH RESEARCH, INC. | $49,358 | Grant | Trans-NIH Recovery Act Research Support: The award is an administrative supplement to NIH grant # R01GM080573, entitled Structural and Mechanistic Studies of Error-Prone Polymerases. The award is designated for the purchase of a multi-mode plate reader, which will greatly accelerate the tempo o | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF IOWA, THE | $200,683 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal of our research is to understand the replication of damaged DNA in eukaryotes at the thermodynamic, kinetic, and structural levels. DNA damage in the template strand blocks replication by classical DNA polymerases. Consequently cells po | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $203,863 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Genetic information is usually represented as linear arrays on chromosomes, yet nuclear DNA exists in a highly compacted form in which access to individual genes must be considered as a three-dimensional problem. Cytol | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BRANDEIS UNIVERSITY | $59,345 | Grant | Trans-NIH Recovery Act Research Support: Dyneins are microtubule-based motor enzymes that convert chemical energy into mechanical work. The dynein motors occur either in the cytoplasm, where they mediate retrograde transport, or within the integral structure of cilia and flagella, where they gen | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| FLORIDA STATE UNIVERSITY, THE | $110,250 | Grant | Trans-NIH Recovery Act Research Support: All cells contain the same genetic information (DNA) but package it with proteins into G?chromatinG? in characteristic ways that define each cell type, with unnecessary information packaged tightly out of the way and relevant information available to main | Health and Human Services, Department of / National Institutes of Health | 8/31/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $226,376 | Grant | Trans-NIH Recovery Act Research Support: This application is to request funds to purchase an inverted fluorescence microscope and to employ a postdoctoral associate for 18 months. Both Specific Aims require the extensive use of a fluorescence microscope. Currently, our access to a fluorescence m | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| UNIVERSITY OF MARYLAND | $173,887 | Grant | Trans-NIH Recovery Act Research Support: Pyrrolobenzodiazepines (PBDs) are compounds naturally produced by bacteria with potent antitumor properties. PBDs' remarkable broad spectrum of activities and effectiveness against a wide variety of cancers encourages the development of new PBDs. We are p | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK INC | $58,786 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement funded under the American Recovery and Reinvestment Act is directed towards the purchase of equipment to enhance the tempo of research in the parent R01 grant entitled The Chemistry and Biology of Resveratrol-based Oligomers | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| EMORY UNIVERSITY | $635,483 | Grant | Trans-NIH Recovery Act Research Support: Metadata analysis of Glycan Structure (MAGS) is essential for defining the human glycome and will contribute to diagnosing altered glycosylation associated with many human diseases. There are two specific aims that we are adding to this competitive revisi | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF UTAH, THE | $315,083 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Progressive mitochondrial oxidative damage and dysfunction is fundamental to the pathogenesis of many human diseases. Using a yeast model system, we have shown that the novel protein Lifespan-associated Mitochondrial S | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF WASHINGTON | $198,342 | Grant | Trans-NIH Recovery Act Research Support: We seek to accelerate the pace of research proposed in parent grant 'Structural & Functional Characterization of BRCA1/BARD1' by 1) acquiring equipment that will overcome bottlenecks and 2) hiring an additional research technician to increase the rate of | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $41,283 | Grant | Trans-NIH Recovery Act Research Support: The onset of puberty at the normal age is very important, as any deviation from peer age can result in psychological perturbation. Moreover, disorders associated with precocious and delayed puberty, and many diseases such as polycystic ovarian syndrome, e | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BAYLOR COLLEGE OF MEDICINE | $89,119 | Grant | Trans-NIH Recovery Act Research Support: Congenital diaphragmatic hernia (CDH), a life-threatening birth defect, is a major cause of pediatric mortality and mobility. The pathological anomalies are characterized by the inappropriate protrusion of the abdominal contents, possibly including the st | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF MASSACHUSETTS | $74,570 | Grant | Trans-NIH Recovery Act Research Support: The proposed research examines how English readers and listeners use their knowledge of the semantic structure of their language to comprehend sentences and discourse. It builds on earlier research examining how they use syntactic structure, extending it | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| WASHINGTON STATE UNIVERSITY | $74,750 | Grant | Trans-NIH Recovery Act Research Support: Despite the importance of maternal meiotic errors to the genesis of human chromosome abnormalities, we know very little about chromosome dynamics during human female meiosis, and remain ignorant of the reasons why the process is so error-prone. Under the | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| CARNEGIE INSTITUTION OF WASHINGTON | $75,722 | Grant | Trans-NIH Recovery Act Research Support: The project aims to futher elucidate these two observations of the hormone - expressing PVN and SON neurons in order to better understand both hypothalamic development and fuction. | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $36,416 | Grant | Trans-NIH Recovery Act Research Support: The National Survey of Adolescent Males (NSAM) Center for Adolescent Health, Johns Hopkins Bloomberg School of Public Health. The main impetus of the original (parent) grant, NSAM: Wave 4: HIV/STD Risk Trajectories is to gain a more comprehensive and deve | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $287,235 | Grant | Trans-NIH Recovery Act Research Support: NSAM Fourth Wave: Respondent tracing and in-person interviewing. In September 2009 we received an administrative supplement from Recovery Act funds ($287,235) to continue our in-person efforts to interview NSAM respondents. These funds supplemented an NIH | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $257,532 | Grant | Trans-NIH Recovery Act Research Support: Epigenetic inheritance is defined as cellular information, other than the DNA sequence itself, which is heritable during cell division. Epigenetic aberrations can lead to diseases such as childhood cancer and developmental defects and because heritable na | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| MEDICAL UNIVERSITY OF SOUTH CAROLINA | $366,378 | Grant | Trans-NIH Recovery Act Research Support: The outcome from this supplemental application is to not only to enhance the existing specific aims through the training and hiring of a targeted faculty member, but to update and enhance this targeted faculty members??? research capabilities. Through pro | Health and Human Services, Department of / National Institutes of Health | 7/30/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $235,573 | Grant | Trans-NIH Recovery Act Research Support: Chronic beryllium disease (CBD) is a granulomatous lung disorder caused by beryllium exposure in the workplace and is characterized by the accumulation of beryllium-specific CD4+ T cells in the lung. Due to its unique chemical and physical properties, ber | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF NEVADA, RENO | $561,378 | Grant | Trans-NIH Recovery Act Research Support: This supplemental project will recruit an additional 240 college freshmen to serve as a non-equivalent assessment only control group to the parent project, which is evaluating through a randomized controlled trial (N = 720) a classroom-based intervention | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| NEW YORK UNIVERSITY (INC) | $271,870 | Grant | Trans-NIH Recovery Act Research Support: Na?-dependent neurotransmitter transporters of the presynaptic plasma membrane function in the reuptake of neurotransmitters from the synaptic cleft. These proteins include the serotonin transporter (SERT), norepinephrine transporter (NET) and dopamine tr | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| TEXAS ENGINEERING EXPERIMENT STATION | $90,830 | Grant | Trans-NIH Recovery Act Research Support: Tissue engineered vascular grafts (TEVGs) may provide vessel replacements when conventional prostheses are unavailable or fail. Researchers are taking multiple approaches toward fabricating viable TEVGs, including the development of designer scaffolds. A | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $277,707 | Grant | Trans-NIH Recovery Act Research Support: The specific aims of our Administrative Supplement grant will be in parallel with the original R21 grant. In Aim 1, we propose that a combination of novel molecular imaging technology and traditional immunohistochemistry will prove effective for understan | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $93,602 | Grant | Trans-NIH Recovery Act Research Support: Huntington's Disease (HD) is an autosomal dominant neurological disorder caused by the inheritance of a CAG repeat greater than 36 in length in exon 1 of a gene of unknown function, huntingting. There is no known cure for this lethal neurological disorde | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| CATHOLIC HEALTHCARE WEST | $109,870 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to determine if Allelic Expression Imbalance of the TSC genes (TSC1 and TSC2) plays an important role in variability of phenotype in familial cases of tuberous sclerosis complex. This ARRA Administrative Supplement will allow | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $16,344 | Grant | Trans-NIH Recovery Act Research Support: Supplement to fund a high school student to work in a basic research lab for the summer. The goal was to provide a training experience for the student and to advance the aims of the parent grant which are to improve cardiovascular health. | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $166,273 | Grant | Trans-NIH Recovery Act Research Support: New treatments are needed to decrease the complications of atherosclerosis, which include death, disability, heart attack, and amputation. Notably, collateral artery formation that naturally bypasses arterial obstructions occurs in all patients, but to a | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF ILLINOIS | $271,141 | Grant | Trans-NIH Recovery Act Research Support: This is an Administrative Supplement grant for parent grant entitled Reactive oxygen species and endothelial migration funded from March 15/2006 to February 28/2011. The parent grant proposes to study the molecular mechanisms by which reactive oxygen spe | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $182,965 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Humans that inherit mutations in the Mre11 gene suffer from extreme sensitivity to ionizing radiation, develop cerebellar degeneration, and have frequent chromosomal translocations in circulating lymphocytes. In additi | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $25,392 | Grant | Trans-NIH Recovery Act Research Support: This project occurred at a subcontract site, Gustavus University. The goal of this project is to give undergraduate students research experience to attract them into science. The ability to engage students in thinking about solving problems of real biome | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $182,814 | Grant | Trans-NIH Recovery Act Research Support: The Cardiovascular Effects of Obstructive Sleep Apnea (COSA) study is a randomized trial funded by NHLBI through grant 5R01HL80076 , in which 195 adults with obesity (BMI30 kg m2), moderate to severe obstructive sleep apnea (apnea hypopnea index 15), and | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MOUNT SINAI SCHOOL OF MEDICINE | $155,377 | Grant | Trans-NIH Recovery Act Research Support: Pressure overload-induced cardiac hypertrophy is one of the most common causes of heart failure. Many intracellular signal transduction pathways have been implicated in the development of cardiac hypertrophy and the progression of hypertrophy to heart fai | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF FLORIDA | $167,359 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the parent proposal (HL081577) has been to investigate the hypothesis that transcription factor Nkx2.5 actively regulates a critical set of genes in postnatal cardiomyocytes to maintain proper cardiac function. Specifically, we ha | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $126,900 | Grant | Trans-NIH Recovery Act Research Support: Nitric oxide (NO) has been shown in vitro to play an important role in the regulation of oxygen consumption on the mitochondrial respiratory chain. Our preliminary data demonstrated that oxygen consumption in the postischemic in vivo mouse heart was suppr | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| EAST CAROLINA UNIVERSITY | $228,326 | Grant | Trans-NIH Recovery Act Research Support: This ARRA-sponsored administrative supplement under NIH notice NOT-OD-09-056 is designed to accelerate the tempo and achievement of scientific research through the promotion of job creation and economic development while at the same time making inroads in | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LOUISIANA STATE UNIVERSITY SYSTEM | $214,625 | Grant | Trans-NIH Recovery Act Research Support: Cardiovascular disease is now considered a major complication in the treatment of HIV. While a large number of clinical trials have examined the relationship between atherosclerosis and either the HIV infection or the antiretroviral treatment of HIV, no d | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $303,388 | Grant | Trans-NIH Recovery Act Research Support: This funding will allow us to create a new position within our parent R01 grant to hire a post-doctoral fellow to perform additional experiments to accelerate the pace of our research in morphogenesis of alveolar epithelial type I cells. The objective of | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CHILDRENS HOSPITAL OF PHILADELPHIA | $20,661 | Grant | Trans-NIH Recovery Act Research Support: Heparin-induced thrombocytopenia (HIT) is an iatrogenic cause of thrombocytopenia and thrombosis due to antibodies to complexes between Platelet Factor 4 (PF4) and heparin. Around half of heparinized patients develop such antibodies after cardiopulmonary | Health and Human Services, Department of / National Institutes of Health | 6/08/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $253,186 | Grant | Trans-NIH Recovery Act Research Support: The results on coronary endothelial function on the parent RO1 are very promising. Different degrees of coronary atherosclerosis can be identified non-invasively using MRI. However, the related quantitative analysis of coronary artery endothelial function | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE | $183,286 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement was submitted in association with a previously funded R01, HL084200, G?Reciprocal regulation of SDF-1 between marrow and lung during acute lung injury.G? The supplement will be used to accelerate progress on this project by | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $218,973 | Grant | Trans-NIH Recovery Act Research Support: Stroke mortality is the 3rd leading cause of death in the U.S. and a leading cause of long-term disability. Several stroke risk factors have been identified, but the role of psychosocial factors in stroke risk is poorly understood. Depressive symptoms, ho | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| UNIVERSITY CORPORATION, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: The goals of this program are to improve California State University's (CSUN) research capacity and infrastructure and to increase minority participation in basic biomedical research. The majority of the students who attend California State University, No | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF MARYLAND | $112,830 | Grant | Trans-NIH Recovery Act Research Support: Quality sleep is imperative for the maintenance of good health. Persons suffering from sleep disturbances are not only fatigued but have impaired memory and learning, increased stress and anxiety and decreased quality of daily life. Sleep disturbances are | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| DUKE UNIVERSITY | $154,850 | Grant | Trans-NIH Recovery Act Research Support: Our lab studies genotype by sex interaction in the etiology of metabolic traits, including dsylipidemia and diabetes. Through our work on the high density lipoprotein receptor, scavenger receptor class B type 1 (SR-BI), we have identified two distinct pol | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $12,560 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the award was two fold: first, to facilitate the goals of the parent grant, R01 HL085218 and second, to provide funding to support summer research by a high school or undergraduate student. | Health and Human Services, Department of / National Institutes of Health | 6/02/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $263,763 | Grant | Trans-NIH Recovery Act Research Support: In our parent grant, we hypothesize that DUOX2, a dual oxidase/peroxidase enzyme, is a central component for host defense against rhinovirus (RV) infection in respiratory tract epithelium. The goals of the experiments outlined in the parent grant are to e | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| NORTHWESTERN UNIVERSITY | $251,573 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement is to fund a fulltime post doctoral fellow to support the completion of the in vitro experiments and to train more investigators in the field of valvular heart disease. | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERISTY OF MISSISSIPPI MEDICAL CENTER | $200,910 | Grant | Trans-NIH Recovery Act Research Support: Obesity and insulin resistance are major risk factors for hypertension, vascular, and renal disease; however, the mechanisms contributing to this have not been fully elucidated. Increased visceral adiposity seems to impart a significant cardiovascular ri | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $300,187 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests supplemental funding to hire additional scientific staff and accelerate the pace of discovery related to a Parent R01 project entitled G?FGF-10 Expression in a Fetal Mouse Lung Model of Bronchopulmonary Dysplasia.G? Novel, unexpecte | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CHICAGO, THE | $132,374 | Grant | Trans-NIH Recovery Act Research Support: Epidemiologic data have shown associations between short sleep duration and elevated body mass index (BMI). So far, the major evidence in support of a causal mechanism comes from our laboratory studies of healthy young adults submitted to sleep restrictio | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $151,500 | Grant | Trans-NIH Recovery Act Research Support: The central goals of this project are to develop reliable non-invasive methods using echocardiography to identify recovery of left ventricular (LV) function in heart failure patients supported by LV assist device (LVAD) and to develop novel bioengineering | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $180,457 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Atrial fibrillation (AF) is the most common adult cardiac tachyarrhythmia affecting more than 2,200,000 people in the US. AF also accounts for 15% of all strokes. Ectopic electrical impulses originating in the pulmona | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $252,791 | Grant | Trans-NIH Recovery Act Research Support: Cardiovascular disease is the number one killer in the US. The incidence and severity of inflammatory heart disease (myocarditis) is higher among men. Proinflammatory cytokines are critical for the development of myocarditis. Recent evidence suggests a li | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF KENTUCKY | $150,223 | Grant | Trans-NIH Recovery Act Research Support: Every year, sudden cardiac death claims up to 25,000 people that do not have structural heart disease. Genetic and acquired causes for these cases of sudden cardiac death are increasingly being sought, and hundreds of mutations have been linked to the pro | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| WAYNE STATE UNIVERSITY (INC) | $121,345 | Grant | Trans-NIH Recovery Act Research Support: Reward funds were used to support the postdoctoral fellow in administering interviews to youth with asthma and their parents to better understand the impact of beliefs about asthma and asthma management on care choices. Data collection was completed (24 y | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF CINCINNATI | $267,314 | Grant | Trans-NIH Recovery Act Research Support: Heart disease is a leading cause of death worldwide. Increasing evidence indicates that apoptosis, associated with detrimental structural and functional alterations, is a major contributor in the progression of cardiac remodeling and heart failure. Thus, | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| NEVADA CANCER INSTITUTE | $60,835 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies are based on our innovative and productive nature of the ongoing work (see our recent publications) and the value to this work that the new employee, a postdoc is being brought in. Our hypothesis, which is supported by our unique mode | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF MARYLAND | $273,614 | Grant | Trans-NIH Recovery Act Research Support: Graft-versus-host disease (GVHD) is caused by orchestrated host-reactive donor T cell responses and remains a major complication of allogeneic bone marrow transplantation (BMT) or hematopoietic stem cell transplantation. Although GVHD can be attenuated by | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $219,040 | Grant | Trans-NIH Recovery Act Research Support: Determinants of AAV Lung Tropism ARRA PURPOSE OF THE SUPPLEMENT Aim 1 of the parent R01 hinges on highthroughput molecular cloning, while Aim 2 exploits traditional biochemical assays to elucidate molecular aspects of AAV lung tropism. The current supp | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| MAYO CLINIC | $145,913 | Grant | Trans-NIH Recovery Act Research Support: This proposal seeks ARRA supplemental administrative funding for the hiring of a recent college graduate. The parent grant (HL-89331) is currently in year two out of five, and was awarded to Dr. Eisenach as a New Investigator. The scientific activities pr | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| RUSH UNIVERSITY MEDICAL CENTER | $264,924 | Grant | Trans-NIH Recovery Act Research Support: The goal of this application is to support a research employment opportunity for a postdoctoral fellow with strong molecular biology expertise needed to accomplish several studies within the peer-reviewed and approved parental grant HL089462. These studie | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| THE VANDERBILT UNIVERSITY | $18,755 | Grant | Trans-NIH Recovery Act Research Support: The period immediately following hospitalization is a vulnerable time for patients. After hospital discharge, approximately 40% of patients experience at least 1 serious medication error, a term that includes adverse drug events as well as potentially har | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF WASHINGTON | $249,136 | Grant | Trans-NIH Recovery Act Research Support: Work on this R01 study has progressed rapidly and has revealed significant new information regarding the role for genetics in determining innate immune-mediated inflammatory cytokine production and gene expression. These studies have been performed usi | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE/CWRU | $250,814 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Atrial fibrillation (AF) is a complex arrhythmia that afflicts more than 2.3 million Americans. Most prevalent in the elderly, AF is associated with a 2-fold higher risk for mortality. AF is the most potent risk factor | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $384,866 | Grant | Trans-NIH Recovery Act Research Support: The incidence of sudden cardiac death (SCD) after myocardial infarction (MI) has remained unchanged and is most significant in the first year after MI. The marked cellular anisotropy observed in the peri-infarct zone has reported to be a potential cause o | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $246,371 | Grant | Trans-NIH Recovery Act Research Support: Respiratory infection has been associated with various lung diseases such as pneumonia, cystic fibrosis, and tuberculosis. Annual economic costs of respiratory tract infections in the United States are conservatively estimated to exceed 15 billion dollar | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| REGENTS OF THE UNIVERSITY OF COLORADO, THE | $320,525 | Grant | Trans-NIH Recovery Act Research Support: Extracellular nucleotides liberated at inflammatory tissue sites are metabolized to adenosine by surface expressed ecto-nucleotidases (CD73 and CD39). Ongoing studies indicate that adenosine liberated by this process is available to activate surface adeno | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LOYOLA UNIVERSITY | $265,512 | Grant | Trans-NIH Recovery Act Research Support: The applicant proposes a 2-AIM strategy to explore molecular mechanisms of SERCA calcium pump regulation by its major binding partner PLB. AIM1 describes the use of fluorescence resonance energy transfer (FRET) to quantify the AFFINITY of PLB binding inte | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $15,700 | Grant | Trans-NIH Recovery Act Research Support: Mutations in three different genes (TERT, TERC, and SFTPA2) cause human pulmonary fibrosis. Recuritment of talented students to work alongside laboratory personnel will expedite the research in this field and encourage them to pursue a career in the heal | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $228,568 | Grant | Trans-NIH Recovery Act Research Support: Telomere lengths of human chromosomes shorten with age. Accelerated telomere shortening is associated with multiple different diseases of older adults such as pulmonary fibrosis, atherosclerosis and osteoporosis. Measurement of telomere lengths in a la | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| OREGON HEALTH & SCIENCE UNIVERSITY | $153,745 | Grant | Trans-NIH Recovery Act Research Support: Non-invasive techniques for imaging blood flow - down to capillary-level resolution - are of paramount importance in order to research and diagnose diseases that have vascular etiology or involvement. Current optical imaging techniques are able to achieve | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS | $15,700 | Grant | Trans-NIH Recovery Act Research Support: Mutation in the gene for the ABCA3 transporter cause a variety of lung diseases that result in either death in the immediate newborn period or chronic lung disease in children and into adulthood. We have created mouse models of the human ABCA3 mutations | Health and Human Services, Department of / National Institutes of Health | 6/19/2009 |
| UNIVERSITY OF ARIZONA | $176,598 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement request seeks to accelerate the identification of inflammatory and auto-immune predictors of COPD development and mortality and, in turn, addresses the 2009 America Recovery and Reinvestments Act by enhancing the tempo of th | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| NEW YORK UNIVERSITY (INC) | $165,263 | Grant | Trans-NIH Recovery Act Research Support: In our current active grant, Diabetic Foot and Pressure Ulcer Databank [R01LM008443], we aimed to determine if use of the Wound Electronic Medical Record (WEMR) as an intervention could decrease progression of diabetic foot ulcers to amputation and early | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| NEW JERSEY INSTITUTE OF TECHNOLOGY | $118,960 | Grant | Trans-NIH Recovery Act Research Support: Award title: Taxonomies Supporting Orientation, Navigation and Auditing of Terminologies/Admin Supplement. The proposed research supports our original grant concerning utilizing taxonomies for the SNOMED terminology. These taxonomies have been found help | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $134,801 | Grant | Trans-NIH Recovery Act Research Support: Susceptibility to sporadic forms of cancer is determined by numerous genetic factors that interact in a nonlinear manner in the context of an individual's age and environmental exposure. This complex genetic architecture has important implications for the | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $98,339 | Grant | Trans-NIH Recovery Act Research Support: Susceptibility to sporadic forms of cancer is determined by numerous genetic factors that interact in a nonlinear manner in the context of an individual's age and environmental exposure. This complex genetic architecture has important implications for the | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF WASHINGTON | $54,450 | Grant | Trans-NIH Recovery Act Research Support: This project will enhance our ability to ensure that our personal health information management tool can connect with the existing personal health record system for Microsoft's HealthVault and increase the value and efficiency with which we can conduct ou | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| RENSSELAER POLYTECHNIC INSTITUTE | $170,861 | Grant | Trans-NIH Recovery Act Research Support: The principal objective of this project is to develop methods that combine pathogen genotyping and patient epidemiology data that can be used in the control, understanding, and tracking of infectious diseases | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $25,597 | Grant | Trans-NIH Recovery Act Research Support: This application is a competitive renewal of an R01 that is nearing the end of its 10th year of funding. Previously the focus of research was on gray matter abnormalities in schizophrenia. In the current five-year application, we now turn to the investiga | Health and Human Services, Department of / National Institutes of Health | 6/10/2009 |
| NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION, INC. | $92,025 | Grant | Trans-NIH Recovery Act Research Support: We are requesting a 2-year administrative supplement to our R01 (MH058262 Corollary Discharge Dysfunction in Schizophrenia: ERP's and EEG) and the linked K02 (MH067967: Neurobiology of response failure in schizophrenia) grants, which were funded last year | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| THE VANDERBILT UNIVERSITY | $318,677 | Grant | Trans-NIH Recovery Act Research Support: The proposed administrative supplement is structured to accelerate the pace of discovery for one of the key aims of the parent R01 - specifically to describe the timeline for the appearance and maturation of cortical multisensory circuits. The expanded sc | Health and Human Services, Department of / National Institutes of Health | 7/28/2009 |
| BAYLOR COLLEGE OF MEDICINE | $160,514 | Grant | Trans-NIH Recovery Act Research Support: Two-photon confocal microscopy to study in vivo the biophysical implementation of multiplication and invariance. We propose to construct a two-photon confocal microscope to study synaptic integration in vivo in a visual neuron that detects impending colli | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF PITTSBURGH THE | $249,954 | Grant | Trans-NIH Recovery Act Research Support: In this administrative supplement, consistent with the NIH-wide emphasis on personalized medicine, we will develop methods for creating comprehensive profiles of treatment outcomes in major depression with the goal of simultaneously capturing multiple asp | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $349,389 | Grant | Trans-NIH Recovery Act Research Support: This is an application for an R01 grant entitled, 'Novel DT-MRI Analyses of White Matter in Schizophrenia'. The goal of this five-year award is to apply new approaches for evaluating white matter abnormalities in schizophrenia using Diffusion Tensor Magne | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $116,861 | Grant | Trans-NIH Recovery Act Research Support: This diversity administrative supplement is being requested to support the continued research and career development of my graduate student, Alissa Richmond. Alissa is a fourth-year African-American graduate student pursuing a Ph.D. degree in the Biology | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NEW YORK UNIVERSITY (INC) | $253,500 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The goal of this research program is to identify the mechanisms by which axons drive Schwann cell myelination. We had previously reported that type III NRG1 is the long sought instructive signal that determines the ens | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| NEW YORK UNIVERSITY (INC) | $101,338 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal is to understand the biophysics of substance diffusion in brain extracellular space (ECS). Biomedically, this proposal will enhance understanding of impediments to drug delivery in brain and factors that affect chemical signaling in the | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $423,104 | Grant | Trans-NIH Recovery Act Research Support: This is an ARRA award to support supplementary research of the project entitled Electrical Stimulation of Immediate Early Genes, which involves basic research to establish the role of neuronal activity-induced gene expression in nervous system function. S | Health and Human Services, Department of / National Institutes of Health | 9/20/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $168,113 | Grant | Trans-NIH Recovery Act Research Support: We have spent the last two to three years developing a system by which specific cell types can be eliminated in the developing or adult CNS with close spatial and temporal control in the absence of any local insults to the tissue. In the original grant | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $175,414 | Grant | Trans-NIH Recovery Act Research Support: RAF/MEK/ERK Regulation of Axon Growth and Differentiation (ARRA) Funds were requested to accelerate Aims 1 and 4 of the parent proposal. Funds were requested to provide stipend support and associated expenses for two individuals. In addition a request | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $7,800 | Grant | Trans-NIH Recovery Act Research Support: The project was designed to support two undergraduate students to participate in a supervised research project as part of an established summer program. One student worked in the laboratory in summer, 2009 and another student worked in the laboratory in | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| WAKE FOREST UNIVERSITY | $164,585 | Grant | Trans-NIH Recovery Act Research Support: Although several popular theories postulate that the capacity to engage in multisensory integration is already present at birth, and is largely insensitive to experience, observations from the past grant period suggest quite the opposite. Using midbrain a | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| THE WASHINGTON UNIVERSITY | $76,141 | Grant | Trans-NIH Recovery Act Research Support: Egr2 is a zinc finger transcription factor that, along with the Nab family of corepressors, is an important regulator of the Schwann cell (SC) myelination program. Egr2-deficient mice as well as mice deficient in both Nab1 and Nab2 manifest defects in per | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $173,609 | Grant | Trans-NIH Recovery Act Research Support: This project is intended to be the critical test of the role of growth factors in modifying neuropathic and inflammatory pain in the mouse. We now have available genetically engineered lines of knock-in mice in which a small molecule inhibitor can abruptl | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $27,947 | Grant | Trans-NIH Recovery Act Research Support: Estradiol plays a critical role in sexual maturation and receptivity. These effects are well characterized: primarily mediated through intracellular estrogen receptors, estradiol initiates changes in gene expression, leading to alterations in cell excitab | Health and Human Services, Department of / National Institutes of Health | 7/21/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $635,419 | Grant | Trans-NIH Recovery Act Research Support: Mechanisms of Increasing Apoptosis Regulation in Developing and Mature Neurons Post-mitotic cells such as neurons must strictly regulate the pathway of apoptosis because these cells have limited regenerative potential and must survive for the lifetime of | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | $23,175 | Grant | Trans-NIH Recovery Act Research Support: Many previous studies have shown that patients with Parkinson's disease (PD) suffer from a variety of cognitive deficits. Although early studies of these deficits focused primarily on executive or working memory tasks sensitive to frontal lobe impairment, | Health and Human Services, Department of / National Institutes of Health | 7/26/2009 |
| TRUSTEES OF TUFTS COLLEGE INC | $22,096 | Grant | Trans-NIH Recovery Act Research Support: This award is intended to provide a summer research experience for an undergraduate student with an interest in pursuing a career in neuroscience and to accelerate the tempo of work on the parent grant. The hypothesis of the parent grant is that GABA(A) | Health and Human Services, Department of / National Institutes of Health | 7/19/2009 |
| NORTHWESTERN UNIVERSITY | $266,540 | Grant | Trans-NIH Recovery Act Research Support: A request for administrative supplement is being made to carry out additional studies on the role of mast Cells in EAE (Experimental Autoimmune/Allergic Encephalomyelitis). We have made outstanding discoveries regarding the role of a population of mast ce | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATIO | $136,699 | Grant | Trans-NIH Recovery Act Research Support: Alzheimer's disease (AD) is the most prevalent neurological disease among the elderly. Considerable data links vasopeptidases, including enothelin-converting enzymes (ECE)-1, ECE-2, neprilysin (NEP), and angiotensin-converting enzyme (ACE), to the degrada | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $198,180 | Grant | Trans-NIH Recovery Act Research Support: Almost two million people sustain traumatic brain injury each year in the United States alone, with most reporting deficits in working memory. Working memory involves the 'online' storage of information necessary for performing cognitive operations. The p | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| BROWN UNIVERSITY IN PROVIDENCE IN STATE OF RI AND PROVIDENCE PLANTATIONS | $99,539 | Grant | Trans-NIH Recovery Act Research Support: Electrical synapses are specialized connections, comprising gap junctions,that allow ionic current and small organic molecules to pass from one neuron to another. Only in the past few years has it become clear that electrical synapses are a major feature | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $318,525 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to elucidate the function of huntingtin protein, mutation of which underlies Huntingtin's disease (HD). These mutations are expansions of a polyglutamine repeat motif (coded by CAG trinucleotide repeats in the mRNA) within the | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF ROCHESTER | $46,125 | Grant | Trans-NIH Recovery Act Research Support: This supplement-?is intended to accelerate the development of an AAV4-BDNF and noggin-based HD treatment strategy, by expanding our assessment of this approach to the non-human primate brain. We intend to assess the efficacy of AAV4-mediated BDNF/Noggin i | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| LELAND STANFORD JUNIOR UNIVERSITY, THE | $137,293 | Grant | Trans-NIH Recovery Act Research Support: The purpose of the research is to examine the function of a new receptor (G-protein coupled receptor) that controls the process of blood vessel formation, termed angiogenesis, in the brain. We will use genetically engineered mice lacking this receptor to | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $126,226 | Grant | Trans-NIH Recovery Act Research Support: A considerable body of evidence has demonstrated an important role for cholinergic transmission in cognition, memory and behavioral state control. Like other amnestic or dementia-related disorders, diencephalic amnesia is accompanied by cholinergic dysfun | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| J.DAVID GLADSTONE INSTITUTES, THE | $15,796 | Grant | Trans-NIH Recovery Act Research Support: Frontotemporal dementia (FTD), the second most common form of age-dependent dementia, is associated with focal degeneration of the frontal and temporal lobes. This insidious disorder is distinct from Alzheimer's disease (AD). For instance, recent studies | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| NORTHWESTERN UNIVERSITY | $37,308 | Grant | Trans-NIH Recovery Act Research Support: Kainate receptors are a functionally unique sub-family of glutamate-gated ion channels that mediate synaptic transmission, modulate neurotransmitter release and regulate cellular excitability in the central nervous system (CNS). Because of the critical ro | Health and Human Services, Department of / National Institutes of Health | 7/24/2009 |
| UNIVERSITY OF WASHINGTON | $173,099 | Grant | Trans-NIH Recovery Act Research Support: This supplementary grant will fund the development of a 32-channel single cell analyzer for sphingolipid metabolism studies. We will employ micrfabrication technology to manufacture an interface with a set f 32 capillaries to automatically transfer the ce | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $192,168 | Grant | Trans-NIH Recovery Act Research Support: Parkinson's disease (PD) is a progressive neurodegenerative disease. By 2030 the number of individuals with PD will double to 9.3 million because of aging populations, but medications to prevent, or delay the disease may not become available in time. Whil | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| ECOHEALTH ALLIANCE INC. | $204,688 | Grant | Trans-NIH Recovery Act Research Support: This ARRA supplementary award will provide two years of funding for a U.S. Global Health Postdoctoral Scientist. Funding will help us conduct additional work that will 1) substantially accelerate the rate of scientific discovery in our project; 2) use nov | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| GEORGETOWN UNIVERSITY (THE) | $7,675 | Grant | Trans-NIH Recovery Act Research Support: Candida albicans is an opportunistic fungal pathogen and the major cause of human fungal infections. It resides commensally on the mucosal tissues of the human body in immunocompetent individuals. However, it is also responsible for causing superficial mu | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER | $87,912 | Grant | Trans-NIH Recovery Act Research Support: This grant is for summer salary for four full-time undergraduate students to work on the NIH parent grant 17 weeks during the summer. The students are all attending the University of Texas at El Paso and they have been associated with the TTUHSC PI's lab | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $74,743 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of the proposed experiments is to examine the behavioral abilities of mice to hear in several listening situations. We will test the detection of simple sounds in quiet, the monaural temporal resolution acuity, and binaural sound loc | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, THE | $20,020 | Grant | Trans-NIH Recovery Act Research Support: Lung cancer is the leading cause of death in the United States. About 213,380 new cases of lung cancer will be diagnosed in 2008 accounting for over 160,390 deaths annually. Despite recent advances in treatment strategies, the overall 5-year survival rate | Health and Human Services, Department of / National Institutes of Health | 6/16/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $25,265 | Grant | Trans-NIH Recovery Act Research Support: Stroke is a leading cause of long-term disability in the United States and Canada and the third leading cause of death after heart disease and cancer. Many epidemiologic studies have found an association between short-term increases in particulate air pol | Health and Human Services, Department of / National Institutes of Health | 7/10/2009 |
| NORTH DAKOTA STATE UNIVERSITY | $16,910 | Grant | Trans-NIH Recovery Act Research Support: Recent genetic characterization of bacterial heme uptake and transport systems in Pseudomonas aerugenosa and Shigella dysenteriae have raised interesting questions regarding the functional details of heme binding, translocation, and release by the protein | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| NORTH DAKOTA STATE UNIVERSITY | $38,000 | Grant | Trans-NIH Recovery Act Research Support: Recent genetic characterization of bacterial heme uptake and transport systems in Pseudomonas aerugenosa and Shigella dysenteriae have raised interesting questions regarding the functional details of heme binding, translocation, and release by the protei | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (INC) | $55,214 | Grant | Trans-NIH Recovery Act Research Support: To support small scale research projects conducted by faculty in primarily baccalaureate degree-granting domestic institutions. Awards are for up to $75,000 for direct costs (plus applicable indirect costs) for periods not to exceed 36 months. The purpose | Health and Human Services, Department of / National Institutes of Health | 6/01/2009 |
| FLORIDA ATLANTIC UNIVERSITY | $160,250 | Grant | Trans-NIH Recovery Act Research Support: Award Title G?? Interfering with CCL2 and CCR2 to limit tumor growth. Tumor progression and metastasis is linked to immune suppression and tumor growth due to production of angiogenic (e.g. CCL2, CCR2) and matrix degrading molecules (e.g. MMP-9). Ther | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| OLD DOMINION UNIVERSITY RESEARCH FOUNDATION | $34,587 | Grant | Trans-NIH Recovery Act Research Support: Thousands of individuals each year suffer a stroke affecting the left hemisphere of the brain and develop aphasia, an acquired language disability. One of the most sommon symptoms of aphasia is word retrieval impairment, which can disrupt the ability to | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| KENYON COLLEGE | $25,000 | Grant | Trans-NIH Recovery Act Research Support: This request for an administrative supplement to R15tES011130 sough support for the purchase of equipment to perform microinjection experiments with Xenopus laevis embryos, knocking down expression of individual aryl hydrocarbon receptor (AHR) paralogs wi | Health and Human Services, Department of / National Institutes of Health | 8/15/2009 |
| THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK INC | $96,895 | Grant | Trans-NIH Recovery Act Research Support: Gump, B. B. (PI) A number of studies have found that increasing lead (Pb) exposure is associated with increases in cardiovascular disease (CVD; e.g., hypertension) in humans. A mechanism to explain this association remains unclear. A number of studies hav | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF ALABAMA IN HUNTSVILLE | $55,138 | Grant | Trans-NIH Recovery Act Research Support: Ubiquitin is a small protein of only 76 amino acids that functions as a post-translational modification for other proteins. Ubiquitin is one of the most highly conserved proteins known. The past decade has seen an upsurge in knowledge about the ubiquitin | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF TOLEDO, THE | $81,840 | Grant | Trans-NIH Recovery Act Research Support: NF-?B is a sequence-specific transcription factor that plays an important role in the regulation of immune and inflammatory responses, cell proliferation, and cell survival. The activity of NF-?B is very tightly regulated at several different levels incl | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| DUQUESNE UNIVERSITY OF THE HOLY SPIRIT | $124,035 | Grant | Trans-NIH Recovery Act Research Support: Fragile X mental retardation syndrome is the most common form of inherited mental retardation, affecting ~1 in 4000 males and ~ 1 in 8000 females. The syndrome is caused by the loss of a normal cellular protein, named the fragile X mental retardation prot | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| WAYNE STATE UNIVERSITY (INC) | $7,468 | Grant | Trans-NIH Recovery Act Research Support: This project will provide the student with training in basic DNA cloning techniques and bacterial mutant construction, as well as in vivo virulence assays. The student will be able to take the project from initial hypothesis all the way to testing the hyp | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT RIVERSIDE | $39,590 | Grant | Trans-NIH Recovery Act Research Support: Inflammation is a key process in normal wound repair. Upon wounding, cytokines are activated and chemoattract leukocytes, including macrophages, to the wound site. Macrophages are key for the proper formation of granulation tissue because they clean up de | Health and Human Services, Department of / National Institutes of Health | 6/18/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $39,535 | Grant | Trans-NIH Recovery Act Research Support: Recent cases of infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) strains in healthy individuals have raised concerns worldwide. CA-MRSA strains differ from hospital-acquired MRSAs (HA-MRSA) by virtue of their g | Health and Human Services, Department of / National Institutes of Health | 6/04/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $338,521 | Grant | Trans-NIH Recovery Act Research Support: This is an application for a continuation of the Population-Research Infrastructure Award to the Center for Social and Demographic Analysis (CSDA) at the University at Albany, SUNY. CSDA was founded in 1981 and began its period of infrastructural support | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $30,000 | Grant | Trans-NIH Recovery Act Research Support: This is a request under the American Recovery and Reinvestment Act (ARRA) of 2009 for an Administrative Supplement for the R24 grant NICHD R24 HD044964 to the Population Studies Center of the University of Pennsylvania. The current award was last reviewe | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $600,000 | Grant | Trans-NIH Recovery Act Research Support: ARRA A Participatory Intervention to Reduce HIV/STIs in African American Youth-Partnership Supplement This project is a supplement to Project GRACE. Project GRACE is an academic-community collaboration between partners that share the common goal of eli | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $79,923 | Grant | Trans-NIH Recovery Act Research Support: Nonhuman primates are instrumental in research involving Category A-C biodefense pathogens. Cynomolgus macaques (M. Fascicularis) are particularly desirable because they are comparatively inexpensive and widely available. However, little is known about th | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | $93,803 | Grant | Trans-NIH Recovery Act Research Support: The primary aim of this innovative psycho-oncology educational initiative is to improve the delivery of palliative care by chaplains, psychologists and social workers through an intensive advocacy training program. Competitively selected participants will | Health and Human Services, Department of / National Institutes of Health | 9/14/2009 |
| UNIVERSITY OF MARYLAND BALTIMORE COUNTY | $150,120 | Grant | Trans-NIH Recovery Act Research Support: The BSURE Program at UMBC will provide the ten-week residential research program over five years for undergraduates with at least 30 college credits recruited from UMBC and institutions with few opportunities for undergraduate research. Recruitment will | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| UNIVERSITY OF NORTH DAKOTA | $43,200 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant) The University of North Dakota STEER is designed to support undergraduate training in the environmental health sciences within the University of North Dakota. The STEER training program will expand and compliment the o | Health and Human Services, Department of / National Institutes of Health | 6/17/2009 |
| VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY | $86,400 | Grant | Trans-NIH Recovery Act Research Support: Virginia Tech, the largest research university in the Commonwealth of Virginia, proposes to continue its successful Virginia Tech Post-baccalaureate Research and Education program (VT-PREP) for another four years by recruiting and preparing a total of 29- | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| MAYO CLINIC | $151,992 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of our program remains the same: to increase the number of individuals from underrepresented groups who choose biomedical research careers, especially disease-oriented research. Our hypothesis is that more students from underrepresented g | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |
| GEORGETOWN UNIVERSITY (THE) | $301,192 | Grant | Trans-NIH Recovery Act Research Support: Improving Communication between Primary Care Providers and their Trauma Patients Abstract Trauma, especially interpersonal violence, is associated with a variety of emotional complaints, anxiety and depressive disorders, and interpersonal problems, as wel | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| TRUSTEES OF INDIANA UNIVERSITY | $34,504 | Grant | Trans-NIH Recovery Act Research Support: The long term goals of this research are to understand the mechanisms that regulate humanalcohol dehydrogenase (ADH) gene expression, and the physiological and pathological consequences of alterations in ADH expression. We hypothesize that differences in | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| ERNEST GALLO CLINIC AND RESEARCH CENTER | $44,032 | Grant | Trans-NIH Recovery Act Research Support: Award Description: Three of the 5 current specific aims of this MERIT award require patch clamp electrophysiology. These supplemental funds were awarded to purchase components for an electrophysiology set-up to complete these aims. | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF CALIFORNIA, DAVIS | $64,134 | Grant | Trans-NIH Recovery Act Research Support: Institutional training grant supplement for pre-doctoral students. This supplement was given to keep NIH committment of 6 fellows for award period (5 fellows on 5T32GM008799). | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF CALIFORNIA, SAN DIEGO | $199,200 | Grant | Trans-NIH Recovery Act Research Support: Biology is increasingly becoming an information-driven science. There is an enormous demand for biologists who are trained in mathematics and computer science and can think quantitatively. However, current disciplinary graduate training programs are not d | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| UNIVERSITY OF WISCONSIN SYSTEM | $95,982 | Grant | Trans-NIH Recovery Act Research Support: Advances throughout the medical and biological sciences rely to an increasing degree on the principles and methods of statistical analysis. A lab's ability to generate data often outpaces its ability to fully analyze that data; and this can negatively aff | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $92,892 | Grant | Trans-NIH Recovery Act Research Support: Biostatistics plays a fundamental role in medical, biomedical and public health research. Advances in medical technology alone have substantially increased the demand for trained biostatisticians to demonstrate basic scientific knowledge, effectiveness an | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $261,084 | Grant | Trans-NIH Recovery Act Research Support: Goals: The JHU Department of Biostatistics proposes a joint MHS-PhD built upon the existing Bioinformatics MHS and Biostatistics PhD programs. The program's goal is to produce graduates that will be full scientific partners on interdisciplinary biome | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| MASSACHUSETTS GENERAL HOSPITAL, THE | $135,258 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is randomized clinical trial examining the long-term health effects of an intensive weight loss intervention in approximately 5,145 overweight volunteers with type 2 diabetes. Participants are randomized to an intensive lifestyle intervention d | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $120,034 | Grant | Trans-NIH Recovery Act Research Support: This supplement will enable an increase in the scientific impact of Look AHEAD (a multi-center radomized clinical trial to determine the long-term impact of weight loss on cardiovascular mobidity and mortality on over 5,000 overweight individuals with typ | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF MINNESOTA | $146,373 | Grant | Trans-NIH Recovery Act Research Support: Look AHEAD is randomized clinical trial examining the long-term health effects of an intensive weight loss intervention in approximately 5,145 overweight volunteers with type 2 diabetes. Participants are randomized to an intensive lifestyle intervention d | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NEW ENGLAND RESEARCH INSTITUTES, INC. | $627,705 | Grant | Trans-NIH Recovery Act Research Support: The Urinary Incontinence Treatment Network (UITN) is a clinical research network, including nine clinical centers (CCs) and a data coordinating center (DCC), established by the NIH in 2000 to bring quality investigation to incontinence research. The prima | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $445,911 | Grant | Trans-NIH Recovery Act Research Support: Socioemotional functioning plays a central role throughout the life-span and is a major factor in successful aging. Whereas losses are seen in many psychological and physical domains in old age, emotion appears to be an area of functioning that is relativ | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| BIOLOG, INC. | $923,041 | Grant | Trans-NIH Recovery Act Research Support: Phenotype MicroArray Analysis of Fastidious Pathogens: Mycobacterium tuberculosis and other Mycobacterium species are major pathogens around the world. They are part of a larger group of so-called fastidious pathogens that are difficult to study because, | Health and Human Services, Department of / National Institutes of Health | 9/30/2006 |
| MICROBIOTIX INC | $10,360 | Grant | Trans-NIH Recovery Act Research Support: In the parent grant we discussed screening of 100,000 discrete compounds. Microbiotix has recently acquired two new libraries of 50 thousand compounds. The supplemental request is for hiring a summer student for screening the newly acquired libraries as d | Health and Human Services, Department of / National Institutes of Health | 7/14/2009 |
| INNOVATIVE BIOTHERAPIES, INC. | $75,775 | Grant | Trans-NIH Recovery Act Research Support: Award Title: Selective Cytopheresis Therapy in Systemic Inflammatory Response Syndrome. The awarded funds are to be used for the purchase of a specialized microscope and camera documentation system, along with salary support for a technician to run the | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| ADVANCED MICROLABS, LLC | $32,240 | Grant | Trans-NIH Recovery Act Research Support: This grant provided research experience for a total of four people to work as interns in health-related scientific research. | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| CALIFORNIA STATE UNIVERSITY, FULLERTON | $44,135 | Grant | Trans-NIH Recovery Act Research Support: Pacific Islanders high school and college student summer research Internship in cancer and cancer-related health disparities. Overall purpose is to support 20 young Pacific Islanders to enter into health professions education and/or training programs to p | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| UNIVERSITY OF TEXAS AT EL PASO | $170,960 | Grant | Trans-NIH Recovery Act Research Support: The SCORE Program has been in existence at the University of Texas at El Paso for thirty-nine years and has been a major contributor to the growth of Biomedical research on this campus. In our recent SCORE Program renewal application, we requested funding | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF UTAH, THE | $226,106 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): The University of Utah is applying for the second renewal of its training grant with the National Library of Medicine (NLM). Our long term objective is to continue a program of research informatics excellence, carrying | Health and Human Services, Department of / National Institutes of Health | 8/20/2009 |
| THE VANDERBILT UNIVERSITY | $528,108 | Grant | Trans-NIH Recovery Act Research Support: Vanderbilt University requests an Administrative Supplement for T-15 Restoration Slots for 4 Council-approved full-time training positions that were requested but not awarded in the 2006 Vanderbilt University Biomedical Informatics Program training grant | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC. | $199,031 | Grant | Trans-NIH Recovery Act Research Support: The goal of the SEPA: Camp PathOlogical Dissemination to Kansas City, Kansas Public Libraries is to accelerate the dissemination of the family seminar series and the information to increase science literacy, knowledge about clinical trials and insight int | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $108,000 | Grant | Trans-NIH Recovery Act Research Support: This extension of the Framework Program in Global Health at the University of Virginia is designed (1) to develop courses and research experiences that enhance students' and faculty members' abilities to participate in global health research across discip | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON | $108,000 | Grant | Trans-NIH Recovery Act Research Support: As global commerce and immigration have increased, there is an acute need for training programs focused on global health. Galveston is a natural site for such as training program. Galveston is a major port and international trade was the main impetus for | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | $37,775 | Grant | Trans-NIH Recovery Act Research Support: Entry of HIV-1 into target cells involves the interaction of viral envelope proteins with specific cell surface receptors, leading ultimately to fusion of viral and host cell membranes. This multi-step process offers a number of potential targets for drug | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $393,600 | Grant | Trans-NIH Recovery Act Research Support: Sjogren?s syndrome is a systemic autoimmune disease with significant associated morbidity. Defining pathways of therapeutic potential will enable the development of rational therapy for the treatment of Sjogren?s syndrome. The overall goal of this project | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF CHICAGO, THE | $100,000 | Grant | Trans-NIH Recovery Act Research Support: Intestinal homeostasis is the essential and dynamic equilibrium of factors that maintain normalmucosal function, integrity, self-renewal, and host defense. In acute diseases, the pathogenic insult is self-limited and intestinal homeostasis is restored. In | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| BETH ISRAEL DEACONESS MEDICAL CENTER INC | $361,129 | Grant | Trans-NIH Recovery Act Research Support: Uncoupling protein-2 (UCP2) is a mitochondrial protein that negatively regulates ATP production. In pancreatic ?-cells, UCP2 affects glucose-stimulated insulin secretion. UCP2 is also expressed in the brain. In glucose-excited neurons (specifically, POMC | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $98,866 | Grant | Trans-NIH Recovery Act Research Support: The long-term goal is to elucidate structure/function relationships in the microbial sensory rhodopsins, a family of visual pigment-like heptahelical photoreceptors, to elucidate principles of membrane receptor photoactivation and receptor interactions wi | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $253,828 | Grant | Trans-NIH Recovery Act Research Support: ARRA funds are being used for the computational and experimental identification and characterization of key regulatory DNAs in the Drosophila genome. In particular, during the preceding funding period we purchased a research grade compound microscope, wh | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ST. JUDE CHILDREN'S RESEARCH HOSPITAL | $99,252 | Grant | Trans-NIH Recovery Act Research Support: This grant involves exploration of the function of p53 proteins in apoptosis, and in particular, the transcription-independent function of cytosolic p53 and its relationship to transcriptional effects in apoptosis. A major component of this work is based | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF CALIFORNIA, IRVINE | $153,628 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative supplement to an active grant which focuses on a model of childhood Prolonged Febrile Seizures and the mechanisms by which these seizures provoke Temporal Lobe Epilepsy (TLE; R37 NS35439, in effect through 2013).The purpose of th | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| ADVANCED GENETIC SYSTEMS INC | $262,313 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): There is a significant need for novel HIV therapies given the emergence of viruses resistant to existing drug regimens. The Rev-RRE protein-RNA interaction in HIV plays an essential role in the transport of viral mRNA | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| SIALIX, INC. | $34,344 | Grant | Trans-NIH Recovery Act Research Support: Gc-Free, Inc. is currently funded under STTR, 1R41GM080959-01A1, has obtained a 2-year no cost extension, and has received a supplement grant funded under the NIH American Recovery and Reinvestment Act appropriation. The research funded under this supple | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| IMMUNOTOPE INC | $151,800 | Grant | Trans-NIH Recovery Act Research Support: Our over-all goal has been to develop a diagnostic test for the early detection of liver cancer (hepatocellular carcinoma (HCC)) that is more specific and sensitive than existing, approved diagnostic tests and procedures. Using glycoproteomic discovery me | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| INTEGRATED DNA TECHNOLOGIES INC | $99,750 | Grant | Trans-NIH Recovery Act Research Support: The National Institutes of Health awarded IDT a Phase 1 SBIR grant (GM085863-01) effective Aug 15, 2008. The project relates to development of U1 Adaptors, a new class of synthetic nucleic acids that are capable of specific down regulation of gene expres | Health and Human Services, Department of / National Institutes of Health | 8/17/2009 |
| ADVANCED MEDICAL ELECTRONICS CORPORATION | $118,409 | Grant | Trans-NIH Recovery Act Research Support: This administrative supplement award provided funding for a mechanical engineer to accelerate the tempo of the research | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| SYNTRIX BIOCHIP, INC. | $200,000 | Grant | Trans-NIH Recovery Act Research Support: Project title - Snap-To-It probes. The award is an NIH/NCI workforce enhancement for an existing SBIR phase II grant to develop ultra-specific DNA microarrays for breast cancer gene analysis. | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| OPTIMUM THERAPEUTICS LLC | $400,000 | Grant | Trans-NIH Recovery Act Research Support: Non-muscle invading bladder cancer, due to its extra-systemic and easily accessible location (i.e., surface of the bladder cavity) and its early diagnosis, is one of the least lethal cancers. However, recurrence is common and is sometimes accompanied by p | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| TECHSHOT, INC. | $68,251 | Grant | Trans-NIH Recovery Act Research Support: The parent grant is 2R44DK 072647-03 G?Magnetic Flow Sorter for Pancreatic Islet IsolationG?. The three stated specific aims of the parent grant are (1) Develop a magnetically activated isolation system (Quadrupole Magnetic Sorting G?? QMS) for purifying | Health and Human Services, Department of / National Institutes of Health | 7/13/2009 |
| CELLONIX CORP. | $82,295 | Grant | Trans-NIH Recovery Act Research Support: The main objective of the Phase II proposal is to commercialize the SBS standard format microfluidic bioreactor array developed in Phase I for high throughput physiologic cell-based screening in the pharmaceutical and biotechnology industry, with special | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| LYNNTECH INC. | $405,605 | Grant | Trans-NIH Recovery Act Research Support: A Novel Nanocomposite Photocatalyst for Water Treatment; The availability of safe drinking water is an important health concern. The introduction of water chlorination as a standard water treatment has resulted in a significant decrease in the number of w | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| PHYLONIX PHARMACEUTICALS, INC. | $49,280 | Grant | Trans-NIH Recovery Act Research Support: NIH Notice NOT-OD-09-060. Administrative Supplement providing summer research experiences for students and science educators. Hire 2 summer students in 2009 and 2010 to speed up the tempo of research on an existing funded grant. Students provide general l | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| INTEGRAL MOLECULAR, INC | $171,804 | Grant | Trans-NIH Recovery Act Research Support: Understanding the precise molecular interactions between drugs and their targets, their structure-activity relationship (SAR), is a highly desirable goal during drug development. GPCRs are the single largest family of drug targets in the pharmaceutical in | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF MIAMI | $382,500 | Grant | Trans-NIH Recovery Act Research Support: The processes by which activated T cells develop into armed effector cells or ultimately persist as long-lived memory cells are becoming better understood. Signal transduction through the IL-2R prominently contributes to these processes. IL-2 promotes opt | Health and Human Services, Department of / National Institutes of Health | 8/28/2009 |
| UNIVERSITY OF TEXAS AT AUSTIN | $370,999 | Grant | Trans-NIH Recovery Act Research Support: Vibrio cholerae, a major human pathogen responsible for both endemic and epidemic cholera, has an absolute requirement for iron.Because V.cholerae must be able to obtain iron in a variety of different environments in and outside of host organisms,it has e | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $367,801 | Grant | Trans-NIH Recovery Act Research Support: Francisella tularensis Interactions with Airway Epithelial Cells (ARRA) This award supports a research project to determine the mechanisms by which the highly virulent bacterial pathogen Francisella tularensis interacts with lung epithelial cells, and ho | Health and Human Services, Department of / National Institutes of Health | 5/29/2009 |
| AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC, THE | $456,250 | Grant | Trans-NIH Recovery Act Research Support: The overall purpose of the award is to discover how glycolipids activate Natural Killer T (NKT) cells, a key component of the innate immune system. In learning about the mechanisms of how glycolipids function, we hope to determine whether or not this clas | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| RXBIO INC | $231,011 | Grant | Trans-NIH Recovery Act Research Support: The Gastrointestinal (GI) mucosa is one of the most radiosensitive tissues, and radiation-associated GI injury could be fatal. Supported by grant 1RC1AI078512-01, we have demonstrated that Rx100 is a potent radiomitigator in the GI tract with a dose-modif | Health and Human Services, Department of / National Institutes of Health | 7/27/2009 |
| CAL POLY POMONA FOUNDATION INC | $122,313 | Grant | Trans-NIH Recovery Act Research Support: Clostridium botulinum is an anaerobic spore-forming bacterium that produces botulinum neurotoxin, the most potent protein toxin, which is known to cause botulism in humans and animals. There are seven serotypes of botulinum neurotoxins (A - G), produced f | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| UNIVERSITY OF TEXAS AT SAN ANTONIO | $124,117 | Grant | Trans-NIH Recovery Act Research Support: A complex system such as the cell can be modeled by a network, whose nodes represent components in the system (e.g., genes) and edges represent relationships between components (e.g., interactions). An interesting property that seems to be ubiquitous amon | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UMDNJ-ROBERT WOOD JOHNSON MEDICAL SCHOOL | $318,667 | Grant | Trans-NIH Recovery Act Research Support: We have demonstrated previously that inactivation of eEF2 kinase can protect mice from the lethal effect of gamma radiation and can protect intestinal stem cells from radiation-induced apoptosis. The goal of our project is to identify eEF2 kinase inhibito | Health and Human Services, Department of / National Institutes of Health | 8/13/2009 |
| UNIVERSITY OF MARYLAND | $221,941 | Grant | Trans-NIH Recovery Act Research Support: The gastrointestinal tract is unique because of its highly proliferative stem cell population and therefore, is second only to the hematopoeitic system in sensitivity to radiation-induced injury. One of the most deleterious effects of radiation injury is | Health and Human Services, Department of / National Institutes of Health | 7/22/2009 |
| CELLERANT THERAPEUTICS, INC. | $500,000 | Grant | Trans-NIH Recovery Act Research Support: Cellerant Therapeutic's goal is to develop an universal off-the shelf cellular therapeutic of megakaryocyte progenitors (MKP) for the mitigation of irradiation induced thrombocytopenia. These progenitors will be derived and expanded ex vivo from hematopoi | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $106,428 | Grant | Trans-NIH Recovery Act Research Support: The plan for this administrative supplement is to recruit undergraduate students from Temple University and faculty members in computer science from a local community college that are interested in enhancing their graphical programming skills. They will b | Health and Human Services, Department of / National Institutes of Health | 8/04/2009 |
| TUFTS MEDICAL CENTER PARENT, INC. | $267,727 | Grant | Trans-NIH Recovery Act Research Support: The proposed studies elucidate a novel biochemical pathway that contributes to blinding retinal degenerations. A better understanding of this pathway may reveal new targets for the development of effective therapies for treatment of retinal degenerations | Health and Human Services, Department of / National Institutes of Health | 9/01/2009 |
| UNIVERSITY OF WASHINGTON | $272,541 | Grant | Trans-NIH Recovery Act Research Support: This proposal is a response to NOT-OD-09-058 Notice of Availability of Recovery Act Funds for Competing Revision Applications. The transmission of genetic material in each cell division requires its accurate duplication and distribution to the daughter | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| GEISINGER CLINIC | $81,054 | Grant | Trans-NIH Recovery Act Research Support: CALCIUM SENSING RECEPTOR AND SCAFFOLDS - The calcium sensing receptor (CaR) transduces local changes in extracellular calcium and metabolites (anrtino acids, polyamines) into intracellular signals, which include acute alterations in cell metabolism and se | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA | $350,890 | Grant | Trans-NIH Recovery Act Research Support: We are requesting an administrative supplement to our parent training program, 'A Systems Engineering Focus on Clinical Informatics' to support two predoctoral and one postdoctoral training fellowships for 2 years each, including stipend, tuition, travel | Health and Human Services, Department of / National Institutes of Health | 7/23/2009 |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | $88,108 | Grant | Trans-NIH Recovery Act Research Support: This award is to add one slot in each of two years of the Cancer Biostatistics training grant. The objective of this program is to trainindividuals to be rigorous and independent academic investigators able to use the range of approaches in biostatistics | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF OREGON | $250,128 | Grant | Trans-NIH Recovery Act Research Support: The basic aspect of the training is laboratory research carried out under the direction of a faculty member in the molecular biology and biophysics training program. Through this experience, the trainee becomes skilled at posing questions about fundamenta | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| NORTHWESTERN UNIVERSITY | $93,930 | Grant | Trans-NIH Recovery Act Research Support: This proposal requests renewal funding for the Predoctoral Biotechnology Training Program at Northwestern University. This interdisciplinary and interdepartmental Program offers biotechnology training opportunities for a select group of PhD students from | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| BAYLOR COLLEGE OF MEDICINE | $136,816 | Grant | Trans-NIH Recovery Act Research Support: This award supports stipends of two graduate students while they pursue their graduate studies in Neuroscience. This application requests continuing support for Predoctoral Training in Systems and Integrative Biology with specific emphasis on Graduate Tr | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| TRUSTEES OF DARTMOUTH COLLEGE | $174,056 | Grant | Trans-NIH Recovery Act Research Support: The goals of the proposed training program are to recruit and train outstanding graduate students and to prepare them for productive careers in science. The trainers in the Molecular and Cellular Biology at Dartmouth Training Program (MCBD) include 53 of | Health and Human Services, Department of / National Institutes of Health | 8/10/2009 |
| UNIVERSITY OF CHICAGO, THE | $87,028 | Grant | Trans-NIH Recovery Act Research Support: The Department of Biochemistry & Molecular Biology (BMB)and the Department of Chemistry (Chem) atThe University of Chicago propose continuation and expansion of an interdisciplinary, predoctoral trainingprogram directed at the interface of the chemical an | Health and Human Services, Department of / National Institutes of Health | 8/03/2009 |
| SAN DIEGO STATE UNIVERSITY FOUNDATION | $305,875 | Grant | Trans-NIH Recovery Act Research Support: This is an administrative ARRA supplement. The parent grant for this supplement is part of the Collaborative Initative on Fetal Alcohol Spectrum Disorders (CIFASD). The primary aim of the parent project is to determine whether a neurobehavioral phenotyp | Health and Human Services, Department of / National Institutes of Health | 7/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $316,208 | Grant | Trans-NIH Recovery Act Research Support: The Women's Interagency HIV Study (WINS) is a large, comprehensive cohort study designed to investigate a spectrum of questions relating to the pathogenesis and natural history of HIV infection among women in the era of highly active antiretroviral t | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $216,153 | Grant | Trans-NIH Recovery Act Research Support: The Duet is a cervical barrier device that, unlike a diaphragm, delivers gel on both its upper and lower surfaces to protect the vagina as well as the cervix. This application proposes 3 related projects: 1) BufferGel-Duet, a single-use product for protec | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| HARVARD COLLEGE, PRESIDENT & FELLOWS OF | $487,798 | Grant | Trans-NIH Recovery Act Research Support: Statistical and Data Management Center - Pediatric, Adolescent and Maternal Clinical Trials Group (CTG) - Exploration, Validity and Predictive Modeling of Host Genetic Factors in HIV Disease Progression in Children | Health and Human Services, Department of / National Institutes of Health | 9/22/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $637,185 | Grant | Trans-NIH Recovery Act Research Support: We are discovering the changes in the genetic code that allow a person?s immune system to tell the difference from another person?s immune system. We hope that this information will help people who need a blood stem cell transplant to treat their cancer l | Health and Human Services, Department of / National Institutes of Health | 8/14/2009 |
| UNIVERSITY OF PITTSBURGH THE | $631,756 | Grant | Trans-NIH Recovery Act Research Support: There are many obstacles to cure of HIV-1 infection especially inadequate knowledge of the reservoirs of HIV-1 persistence. The co-existence of lymphoma requiring treatment in some patients with HIV-1 offers the opportunity to study the impact of cytoabla | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $737,205 | Grant | Trans-NIH Recovery Act Research Support: Three randomized trials, including one which is the basis for this proposal, and numerous observational studies demonstrate that male circumcision reduces male HIV acquisition. We conducted an NIH-funded trial of male circumcision for HIV prevention in ru | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL | $687,693 | Grant | Trans-NIH Recovery Act Research Support: The Cooperative Human Tissue Network (CHTN) was initiated by the Cancer Diagnosis Program of the National Cancer Institute (NCI) in 1987 to provide increased access to human cancer specimens for basic and applied research to accelerate the advancement of | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $748,484 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this U01 application from the Dana-Farber/Harvard Cancer Center (DF/HCC) is to provide clinical and scientific experience and patient resources to perform Phase I single agent clinical trials* Phase I agent combination clinical tr | Health and Human Services, Department of / National Institutes of Health | 7/31/2009 |
| DANA-FARBER CANCER INSTITUTE, INC. | $657,112 | Grant | Trans-NIH Recovery Act Research Support: The overall objective of this U01 application from the Dana-Farber/Harvard Cancer Center (DF/HCC) is to provide clinical and scientific experience and patient resources to perform Phase I single agent clinical trials* Phase I agent combination clinical tr | Health and Human Services, Department of / National Institutes of Health | 8/12/2009 |
| AMERICAN COLLEGE OF RADIOLOGY, THE | $100,001 | Grant | Trans-NIH Recovery Act Research Support: In support of ACRIN's initiative to enhance remote data capture (RDC) systems used to conduct clinical trials; the ADOPT funds will be utilized to develop an Implementation and Integration Plan, User Requirements Specifications, and Platform Requiremen | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| NATIONAL CHILDHOOD CANCER FOUNDATION | $4,023,579 | Grant | Trans-NIH Recovery Act Research Support: This supplemental award provides support to Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Supplements including: 1) High Risk Acute Lymphoblastic Leukemia (HR-ALL) - Our results establish that we can use comprehensive genom | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $163,998 | Grant | Trans-NIH Recovery Act Research Support: IBD Gene Mapping By Clinical and Population Subsets. Inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis, is a complex genetic disorder. The distribution of disease genes varies by ethnic ancestry. Despite the large African Ameri | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| DUKE UNIVERSITY | $110,401 | Grant | Trans-NIH Recovery Act Research Support: In humans with diabetes, abnormal angiogenesis contributes to the development of end-organ damage. In this regard, excessive angiogenesis and increased activity of the vascular endothelial growth factor (VEGF) signaling pathway have been associated with d | Health and Human Services, Department of / National Institutes of Health | 9/04/2009 |
| RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | $79,494 | Grant | Trans-NIH Recovery Act Research Support: Diabetic Uropathy is a term for a range of debilitating urologic complications such as bladder dysfunction, urinary incontinence, urinary tract infection and sexual dysfunction, that are among the most common and costly, yet understudied complications of | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| WASHINGTON UNIVERSITY, THE | $200,640 | Grant | Trans-NIH Recovery Act Research Support: Our understanding of (UCPPS) such as interstitial cystitis/painful bladder syndrome (IC/PBS) and chronic prostatitis/chronic pelvic pain syndrome, (CP/CPPS) is poor. The objective of our proposal is to investigate the etiology, pathophysiology, and epidem | Health and Human Services, Department of / National Institutes of Health | 9/28/2009 |
| NORTHWESTERN UNIVERSITY | $165,059 | Grant | Trans-NIH Recovery Act Research Support: This project examines mechanisms of chronic pelvic pain through a combination of clinical and mouse model studies, and these studies are being conducted at Northwestern University through our participation in the NIDDK Multi-Disciplinary Approaches to Chr | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| UNIVERSITY OF IOWA, THE | $198,000 | Grant | Trans-NIH Recovery Act Research Support: Despite years of research and a considerable monetary expenditure the pathophysiology of the Urologic Chronic Pelvic Pain Syndrome (UCPPS) known as Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) remains elusive. This University of Iowa MAPP grant | Health and Human Services, Department of / National Institutes of Health | 9/27/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $302,915 | Grant | Trans-NIH Recovery Act Research Support: Cigarette smoking is known to contribute to the development of chronic obstructive pulmonary disease (COPD) and lung cancer, with 10-20% of smokers developing these diseases. Previously, our lab has used genome-wide mRNA and microRNA profiling to develop | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $649,313 | Grant | Trans-NIH Recovery Act Research Support: Identification of DNA Elements Governing Chromatin Function C. elegans - 4U01HG004270-03S1 The modENCODE project was established by the NHGRI as an open consortium with the purpose of using computational and experimental approaches to identify all of the | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| NEW YORK UNIVERSITY | $1,000,000 | Grant | Trans-NIH Recovery Act Research Support: This supplement provides project support, for both personnel and other costs, to extend the cloning experiements. To use genome data in medicine we need to build a map of the DNA elements that could affect every gene's activity. We are proposing to bui | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| NORTHWESTERN UNIVERSITY | $65,044 | Grant | Trans-NIH Recovery Act Research Support: This award is issued in response to Notice OD-09-060, Recovery Act Administrative Supplements Providing Summer Research Experiences for Students and Science Educators. This funds will ensure continued employment of fulltime Computer Programmer and allow a | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| UNIVERSITY OF WASHINGTON | $110,730 | Grant | Trans-NIH Recovery Act Research Support: The Gene-Environment Initiative Whole Genome Association project (GENEVA) is generating large amounts of genetic and phenotypic data on large numbers of individuals. The Department of Biostatistics at the University of Washington houses the Coordinating | Health and Human Services, Department of / National Institutes of Health | 6/05/2009 |
| UNIVERSITY OF HAWAII SYSTEMS | $1,018,523 | Grant | Trans-NIH Recovery Act Research Support: In response to RFA-HG-07-014, we propose to use the Multiethnic Cohort (MEC) study to characterize the 'epidemiologic architecture' of putative causal variants identified in large-scale genomic association studies for a wide range of complex traits (chron | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | $477,709 | Grant | Trans-NIH Recovery Act Research Support: The 1000 Genomes Project aims to achieve a nearly complete catalog of common human genetic variants by generating high-quality sequence data surveying the genomes of >1000 individuals. This catalog will include SNPs, copy number variants, and short insert | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| SOUTH CAROLINA RESEARCH FOUNDATION | $209,598 | Grant | Trans-NIH Recovery Act Research Support: A MULTILEVEL HIV PREVENTION STRATEGY FOR HIGH-RISK YOUTH This study continues a program of research that identifies effective safe-sex media messages for African American adolescents at high-rick for sexually transmitted infections (including HIV). Our re | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| CHRISTIANA CARE HEALTH SERVICES, INC. | $239,776 | Grant | Trans-NIH Recovery Act Research Support: To provide services to eligible cancer patients through the Delaware / Christiana Care CCOP. | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| MEHARRY MEDICAL COLLEGE | $261,808 | Grant | Trans-NIH Recovery Act Research Support: The Minority Based Community Clinical Oncology Program at Meharry Medical College supplement will strengthen clinical care and research in hematology and oncology at Meharry Medical College. | Health and Human Services, Department of / National Institutes of Health | 8/27/2009 |
| SALUS UNIVERSITY | $66,402 | Grant | Trans-NIH Recovery Act Research Support: To conduct preliminary comparisons of measurements of macular thickness, optic disc parameters, intraocular pressure (IOP) and central corneal thickness (CCT) between non-myopic young adults and COSMICC subjects. The study is designed to test 2 hypothese | Health and Human Services, Department of / National Institutes of Health | 8/11/2009 |
| CASE WESTERN RESERVE UNIVERSITY | $273,420 | Grant | Trans-NIH Recovery Act Research Support: This continuation of funding for the Cleveland Pediatric Pharmacology Research Unit (PPRU) which was first funded in 1994, one year after the establishment of the PPRU and has been funded since then at a level one-half to two thirds that of the other unit | Health and Human Services, Department of / National Institutes of Health | 7/16/2009 |
| LIUNA TRAINING & EDUCATION FUND | $800,000 | Grant | Trans-NIH Recovery Act Research Support: LIUNA Training & Education Fund (LIUNA Training) (formerly known as Laborers-AGC Education and Training Fund (Laborers-AGC)) is applying for the Hazardous Materials Worker Health and Safety Training cooperative agreement, RFA-ES-04-005 to conduct a Hazard | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| UNIVERSITY OF MEDICINE AND DENTISTRY OF NJ (INC) | $400,000 | Grant | Trans-NIH Recovery Act Research Support: The New Jersey/New York Hazardous Materials Worker Training Center expanded the reach of the HWWT training program to provide knowledge and skills to workers who are unemployed or are less than fully employed. The scope of work includes hazardous waste c | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| OAI, INC. | $482,000 | Grant | Trans-NIH Recovery Act Research Support: OAI, Inc. and its HWWT consortium will provide critical health and safety training for 1,335 newly hired and/or retrained weatherization, construction, environmental remediation and debris removal workers and contractors in Illinois, Louisiana, Maine and | Health and Human Services, Department of / National Institutes of Health | 9/06/2009 |
| UNIVERSITY OF CHICAGO, THE | $911,792 | Grant | Trans-NIH Recovery Act Research Support: Perhaps the greatest current challenge in the treatment of microbial infection is the development of new classes of antibiotics to combat the ever-increasing number of resistant pathogens. However, there are select bacteria that, due to their intracellul | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $1,462,023 | Grant | Trans-NIH Recovery Act Research Support: The Southeast Regional Center of Excellence for Emerging Infections and Biodefense (SERCEB) is an NIH/NIAID-funded consortium of institutions across the southeast established in 2003. SERCEBG??s mission is to assist the nation in developing and deploying | Health and Human Services, Department of / National Institutes of Health | 9/11/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $2,286,398 | Grant | Trans-NIH Recovery Act Research Support: The American Recovery and Reinvestment Act administrative supplement to the Northeast Biodefense Center will support selected research projects for a two-year period. Two projects were chosen based on the level of novelty and their potential to break new | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| COLORADO STATE UNIVERSITY | $1,710,939 | Grant | Trans-NIH Recovery Act Research Support: This application proposes to continue the Rocky Mountain Regional Center of Excellence (RMRCE) for Biodefense and Emerging Infectious Diseases Research located in Region VIII. The RMRCE consists of a highly integrated consortium of universities and federa | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | $52,295 | Grant | Trans-NIH Recovery Act Research Support: The NIH Senator Paul B. Wellstone Centers are the centerpiece of the nation's effort to reduce morbidity and mortality from muscular disorders and are a major source of discovery and development of more effective approaches to prevention, diagnosis, and t | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | $293,000 | Grant | Trans-NIH Recovery Act Research Support: The Transdisciplinary Geographic Management Program (GMaP) for Region 3, henceforth to be known as the GMaP-3 is designed to develop a systematic and comprehensive strategy for building a state-of-the-art network for the support and efficient management o | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| FRED HUTCHINSON CANCER RESEARCH CENTER | $347,116 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of this supplement is to create a hub in Region 6 that connects cancer health disparities researchers and programs. Specifically, we will develop a network of such programs in Region 6, provide an infrastructure for the hub, conduct a nee | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| NEW MEXICO STATE UNIVERSITY | $288,047 | Grant | Trans-NIH Recovery Act Research Support: The BMaP supplemental request for Region 4 (AZ, CO, NM, OK, TX), is submitted on behalf of the region by the NCI MI/CCP U54 award to NMSU (5U54CA132383) funded through August 2012. This supplemental award will fund efforts by NCI supported researchers in | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| CHILDREN'S RESEARCH INSTITUTE | $299,998 | Grant | Trans-NIH Recovery Act Research Support: This proposal for an administrative supplement responds to the NlCHD Recovery Act priority scientific area of Maternal and Child Health. It focuses on effectiveness of pharmaceuticals and applied research in psychological development in children with a co | Health and Human Services, Department of / National Institutes of Health | 9/29/2009 |
| BAYLOR COLLEGE OF MEDICINE | $6,000,000 | Grant | Trans-NIH Recovery Act Research Support: Statement of Purpose: The Human Genome Sequencing Center (HGSC) will perform three levels of tumor/normal analysis. Abstract: This supplement will support tumor profiling at three levels: (a) Basic Cancer Profiling: to detect copy number variation, mea | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MOREHOUSE SCHOOL OF MEDICINE, INC., THE | $599,016 | Grant | Trans-NIH Recovery Act Research Support: The overall goal of the Morehouse/Rochester RIC(Research in Comparative Effectiveness) Network is to establish, in collaboration with the University of Rochester, a practice-based research network that focuses on comparative effectiveness. The developmen | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| UNIVERSITY OF MASSACHUSETTS | $154,000 | Grant | Trans-NIH Recovery Act Research Support: This application describes our plans to develop a comprehensive partnership between the University of Massachusetts Boston (UMB) and the Dana Farber/Harvard Cancer Center (DFHCC). The goal of our partnership is to address health disparities in minority po | Health and Human Services, Department of / National Institutes of Health | 9/15/2009 |
| ROCKEFELLER UNIVERSITY FACULTY AND STUDENTS CLUB INC, THE | $618,491 | Grant | Trans-NIH Recovery Act Research Support: Using the Bleeding History Phenotyping System as a prototype of a comprehensive patient phenotyping instrument, this submission proposes the creation of a comprehensive, ontology-driven phenotyping system and database for Fanconi anemia (FA). FA is a dis | Health and Human Services, Department of / National Institutes of Health | 9/02/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | $396,000 | Grant | Trans-NIH Recovery Act Research Support: The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include | Health and Human Services, Department of / National Institutes of Health | 9/24/2009 |
| UNIVERSITY OF PITTSBURGH THE | $999,999 | Grant | Trans-NIH Recovery Act Research Support: Aim of the Supplement Project: To develop a state of the art Clinical and Translational Vascular Unit (CTVU) to provide a comprehensive assessment of pulmonary and peripheral endothelial function, blood flow, subclinical atherosclerotic disease, and righ | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $983,319 | Grant | Trans-NIH Recovery Act Research Support: Project 1: Synthesis of Neuraminidase Inhibitor (Alice Prince). The goal of this project is the synthesis of neuraminidase inhibitors to prevent the development of pneumonia. Two hits were investigated and SAR profiles were established. Of the compounds p | Health and Human Services, Department of / National Institutes of Health | 9/08/2009 |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | $400,000 | Grant | Trans-NIH Recovery Act Research Support: A call for applications was made on July 30, 2009, for Phase I: Planning Grants for Collaborative & Multidisciplinary Research (CaMPR) Award, the due date was September 14, 2009, and the award announcement was made on November 16, 2009. We received a tot | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| JOHNS HOPKINS UNIVERSITY, THE | $838,278 | Grant | Trans-NIH Recovery Act Research Support: Abstract The purpose of this application is to enhance both the process and benefits of clinical and translational research by bringing together the diverse resources of the Johns Hopkins Medical Institutions (JHMI) and creating a new model for carrying o | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| NORTHWESTERN UNIVERSITY | $992,675 | Grant | Trans-NIH Recovery Act Research Support: This CTSA supplemental award is to advance the pace of development of a centralized informatics support infrastructure for clinical studies, to include a participant enrollment database, electronic data capture, electronic case reporting and clinical tria | Health and Human Services, Department of / National Institutes of Health | 9/07/2009 |
| OHIO STATE UNIVERSITY RESEARCH FOUNDATION | $300,000 | Grant | Trans-NIH Recovery Act Research Support: Engagement of the basic or T1 scientist in the translational science mission is impeded in part by the barriers in rapidly gaining familiarity and expertise in characterizing the physiologic and anatomic relevance of animal models to human disease. These | Health and Human Services, Department of / National Institutes of Health | 9/09/2009 |
| UNIVERSITY OF UTAH, THE | $985,772 | Grant | Trans-NIH Recovery Act Research Support: This amended application, in response to RFA-RM-07-007: 'Institutional Clinical and Translational Science Award', requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS will build upon the University's | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $759,108 | Grant | Trans-NIH Recovery Act Research Support: One of the distinguishing features of our CSTA funded Institute for the Integration of Medicine and Science is the use of Practice?Based Research Networks (PBRNs) to engage community clinicians in meaningful research. We are building on our 17 year histor | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO | $396,496 | Grant | Trans-NIH Recovery Act Research Support: This request for an administrative supplement to our CTSA represents an exciting opportunity to accelerate the pace of translational research through the funding of highly selected competitive pilot projects. The objectives and purposes of this request fa | Health and Human Services, Department of / National Institutes of Health | 9/17/2009 |
| TRUSTEES OF BOSTON UNIVERSITY | $584,994 | Grant | Trans-NIH Recovery Act Research Support: We propose to develop and disseminate a research workforce program for Informatics Education for Behavioral and Social Scientists Engaged in Clinical and Translational Research. The long term objective of this program is to train a cadre of behavioral and | Health and Human Services, Department of / National Institutes of Health | 9/03/2009 |
| SOCIAL & SCIENTIFIC SYSTEMS, INC. | $1,130,883 | Grant | Trans-NIH Recovery Act Research Support: The goal of this project is to increase recruitment and retention of underrepresented and underserved populations into ACTG clinical trials. The ACTG is committed to enrollment of domestic clinical trial participants in proportions that are representative | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | $148,527 | Grant | Trans-NIH Recovery Act Research Support: The Gastroparesis Clinical Research Consortium (GpCRC) is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to focus on the etiology, natural history, and therapy of gastroparesis. The goal of this consortium is to | Health and Human Services, Department of / National Institutes of Health | 9/18/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $650,967 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Prelich, Gregory Project Summary: This application addresses Broad Challenge Area 06 (Enabling Technologies) and Specific Challenge Topic 06-DA-103 (Identification of chemical modulators of epigenetic regulators). Post | Health and Human Services, Department of / National Institutes of Health | 9/21/2009 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $97,684 | Grant | Trans-NIH Recovery Act Research Support: The long-term objectives of this proposal are to understand how the host elicits a pathogen-specific immunological response and generates protective immunity. Listeria monocytogenes is an intracellular bacterium that activates two distinct sets of transc | Health and Human Services, Department of / National Institutes of Health | 7/17/2009 |
| RESEARCH FOUNDATION FOR MENTAL HYGIENE INC | $1,080,698 | Grant | Trans-NIH Recovery Act Research Support: To support research and other projects that will support fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments while also providing economic stimulus to the nation. | Health and Human Services, Department of / National Institutes of Health | 8/01/2009 |
| TUFTS MEDICAL CENTER, INC. | $1,699,448 | Grant | Trans-NIH Recovery Act Research Support: In the most recent data supplied by the American Heart Assocation, cardiovascular disease remained the major underlying cause of death in the United States with the majority of these deaths being due to coronary heart disease and stroke. Given the high pr | Health and Human Services, Department of / National Institutes of Health | 9/23/2009 |
| UNIVERSITY OF IOWA, THE | $2,536,301 | Grant | Trans-NIH Recovery Act Research Support: Dystroglycan is a widely expressed transmembrane glycoprotein that acts as a high- affinity receptor for both extracellular matrix proteins containing laminin-G domains and certain arenaviruses. Secondary dystroglycanopathies encompass a collection of mus | Health and Human Services, Department of / National Institutes of Health | 9/25/2009 |
| WAYNE STATE UNIVERSITY | $441,460 | Grant | Trans-NIH Recovery Act Research Support: The aim of our study is to compare the effectiveness of three complementary and alternative medicine therapies in reducing the level of stress and anxiety in pediatric patients, ages 1-12 years, undergoing sedation for imaging studies and importantly redu | Health and Human Services, Department of / National Institutes of Health | 9/16/2009 |
| UNIVERSITY OF UTAH, THE | $784,738 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION (provided by applicant): Abstract Current estimates place the number of personal variants at approximately 4 million per genome. Given the rapid advances in genome sequencing technologies and the future democratization of human genome sequenci | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY | $2,922,996 | Grant | Trans-NIH Recovery Act Research Support: Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, with an incidence of about 1 in 8,000 adults. The most common form of the disease, DM1, is caused by an expanded CTG repeat in the 3' UTR of the DMPK gene, and CUG repeat R | Health and Human Services, Department of / National Institutes of Health | 9/30/2009 |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | $292,489 | Grant | Trans-NIH Recovery Act Research Support: DESCRIPTION, OVERALL (provided by applicant): An interdisciplinary Liver Research Center was established at the Albert Einstein College of Medicine in 1974 with support from NIDDK. At present, 38 faculty investigators and 3 provisional investigators in 12 | Health and Human Services, Department of / National Institutes of Health | 7/20/2009 |